-- dump date 20140620_084901 -- class Genbank::CDS -- table cds_note -- id note YP_002737247.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002737248.1 binds the polymerase to DNA and acts as a sliding clamp YP_002737249.1 identified by match to protein family HMM PF06107 YP_002737250.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002737251.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002737252.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002737253.1 identified by match to protein family HMM PF01479 YP_002737254.1 identified by match to protein family HMM PF04977 YP_002737257.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433 YP_002737258.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002737259.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241 YP_002737261.1 identified by match to protein family HMM PF01710 YP_002737262.1 identified by glimmer; putative YP_002737264.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002737265.1 identified by match to protein family HMM PF00589 YP_002737266.1 identified by glimmer; putative YP_002737267.1 identified by glimmer; putative YP_002737268.1 identified by glimmer; putative YP_002737269.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002737271.1 identified by match to protein family HMM PF01381 YP_002737276.1 identified by match to protein family HMM PF02498 YP_002737280.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; match to protein family HMM TIGR01714 YP_002737283.1 identified by glimmer; putative YP_002737285.1 identified by glimmer; putative YP_002737287.1 identified by match to protein family HMM PF07852 YP_002737288.1 identified by match to protein family HMM TIGR01671 YP_002737290.1 identified by glimmer; putative YP_002737291.1 identified by match to protein family HMM PF00589 YP_002737292.1 identified by glimmer; putative YP_002737295.1 identified by match to protein family HMM PF03354 YP_002737296.1 identified by glimmer; putative YP_002737297.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537 YP_002737298.1 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543 YP_002737299.1 identified by match to protein family HMM PF05065; match to protein family HMM TIGR01554 YP_002737302.1 identified by match to protein family HMM TIGR01563 YP_002737305.1 identified by match to protein family HMM TIGR01603 YP_002737307.1 identified by match to protein family HMM PF05017 YP_002737309.1 identified by match to protein family HMM TIGR01665 YP_002737311.1 identified by glimmer; putative YP_002737312.1 identified by glimmer; putative YP_002737314.1 identified by glimmer; putative YP_002737315.1 identified by glimmer; putative YP_002737316.1 identified by match to protein family HMM PF05105; match to protein family HMM TIGR01593 YP_002737317.1 identified by match to protein family HMM TIGR01673 YP_002737318.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510 YP_002737320.1 identified by match to protein family HMM PF00383 YP_002737321.1 catalyzes the formation of dUMP from dUTP YP_002737322.1 identified by match to protein family HMM PF00300 YP_002737323.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002737324.1 identified by match to protein family HMM PF00484 YP_002737325.1 identified by glimmer; putative YP_002737327.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002737330.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002737331.1 identified by match to protein family HMM PF02629 YP_002737332.1 identified by glimmer; putative YP_002737333.1 identified by match to protein family HMM PF03601 YP_002737334.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci YP_002737335.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002737336.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002737339.1 identified by match to protein family HMM TIGR01847 YP_002737341.1 identified by glimmer; putative YP_002737342.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_002737343.1 identified by match to protein family HMM TIGR01000 YP_002737344.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002737345.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857 YP_002737346.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002737347.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002737348.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002737349.1 identified by match to protein family HMM PF04892 YP_002737350.1 involved in de novo purine biosynthesis YP_002737351.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002737353.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002737354.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002737356.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002737357.1 identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002737358.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002737359.1 identified by match to protein family HMM PF01301; match to protein family HMM PF02449 YP_002737360.1 identified by match to protein family HMM PF03830 YP_002737361.1 identified by match to protein family HMM PF03609 YP_002737362.1 identified by match to protein family HMM PF03613 YP_002737363.1 identified by match to protein family HMM PF03610 YP_002737364.1 identified by match to protein family HMM PF01380 YP_002737365.1 identified by match to protein family HMM PF01263 YP_002737366.1 identified by match to protein family HMM PF00903 YP_002737367.1 identified by glimmer; putative YP_002737369.1 identified by match to protein family HMM PF00581 YP_002737371.1 identified by match to protein family HMM PF01048 YP_002737372.1 identified by glimmer; putative YP_002737373.1 identified by match to protein family HMM PF02386 YP_002737374.1 identified by match to protein family HMM PF02254 YP_002737375.1 identified by glimmer; putative YP_002737376.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002737377.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002737378.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002737379.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002737380.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737382.1 identified by glimmer; putative YP_002737383.1 identified by match to protein family HMM PF00528 YP_002737384.1 identified by match to protein family HMM PF00528 YP_002737385.1 identified by match to protein family HMM PF01547 YP_002737386.1 identified by match to protein family HMM PF00581 YP_002737391.1 identified by match to protein family HMM PF03551 YP_002737392.1 identified by match to protein family HMM PF07690 YP_002737393.1 identified by match to protein family HMM PF00535 YP_002737394.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002737395.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002737396.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718 YP_002737397.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719 YP_002737398.1 identified by match to protein family HMM PF01476 YP_002737399.1 identified by match to protein family HMM TIGR01653 YP_002737400.1 identified by match to protein family HMM TIGR01654 YP_002737401.1 identified by match to protein family HMM PF00005 YP_002737402.1 identified by match to protein family HMM PF00497 YP_002737403.1 identified by match to protein family HMM PF00764 YP_002737407.1 identified by glimmer; putative YP_002737408.1 identified by glimmer; putative YP_002737415.1 identified by glimmer; putative YP_002737416.1 identified by match to protein family HMM PF01473 YP_002737417.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002737418.1 identified by match to protein family HMM PF00293 YP_002737419.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002737420.1 identified by glimmer; putative YP_002737421.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649 YP_002737422.1 identified by match to protein family HMM PF07288 YP_002737423.1 identified by glimmer; putative YP_002737424.1 identified by match to protein family HMM TIGR01847 YP_002737426.1 identified by match to protein family HMM PF00814 YP_002737427.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_002737428.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002737430.1 identified by match to protein family HMM PF00005 YP_002737432.1 identified by glimmer; putative YP_002737434.1 identified by match to protein family HMM PF02585 YP_002737435.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002737436.1 identified by match to protein family HMM TIGR01716 YP_002737438.1 identified by match to protein family HMM PF02517 YP_002737439.1 identified by match to protein family HMM PF02517 YP_002737441.1 identified by match to protein family HMM PF03591 YP_002737442.1 identified by match to protein family HMM PF00497 YP_002737443.1 identified by match to protein family HMM PF03180 YP_002737444.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687 YP_002737445.1 identified by match to protein family HMM PF00005 YP_002737446.1 identified by match to protein family HMM PF00528 YP_002737447.1 identified by match to protein family HMM TIGR02185 YP_002737448.1 identified by match to protein family HMM PF04854 YP_002737449.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580 YP_002737450.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_002737452.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002737455.1 identified by match to protein family HMM PF04397 YP_002737456.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002737457.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002737458.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506 YP_002737459.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002737460.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326 YP_002737461.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002737462.1 identified by match to protein family HMM PF03352 YP_002737463.1 identified by match to protein family HMM PF02517 YP_002737464.1 identified by match to protein family HMM PF02016 YP_002737465.1 identified by match to protein family HMM PF06570 YP_002737466.1 identified by match to protein family HMM PF01544 YP_002737467.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_002737468.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002737469.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002737471.1 identified by match to protein family HMM PF06135 YP_002737472.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002737473.1 identified by match to protein family HMM PF06949 YP_002737474.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002737476.1 identified by match to protein family HMM PF00614 YP_002737479.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002737481.1 identified by match to protein family HMM PF00583 YP_002737482.1 identified by match to protein family HMM TIGR02491 YP_002737483.1 identified by match to protein family HMM PF00485 YP_002737484.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002737485.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002737486.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002737487.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002737488.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002737489.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002737490.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002737491.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002737492.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002737493.1 one of the stabilizing components for the large ribosomal subunit YP_002737494.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002737495.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002737496.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002737497.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002737498.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002737499.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002737500.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002737501.1 binds 5S rRNA along with protein L5 and L25 YP_002737502.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002737503.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002737504.1 late assembly protein YP_002737505.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002737506.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002737507.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002737508.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002737509.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002737510.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002737511.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002737512.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002737513.1 ACT domain-containing protein YP_002737514.1 identified by match to protein family HMM PF05167 YP_002737515.1 identified by match to protein family HMM PF00300 YP_002737516.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002737517.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002737518.1 identified by match to protein family HMM PF04198 YP_002737519.1 identified by match to protein family HMM PF02255 YP_002737520.1 identified by match to protein family HMM PF02302 YP_002737521.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002737522.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_002737523.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002737524.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002737525.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002737526.1 identified by match to protein family HMM PF00583 YP_002737527.1 identified by match to protein family HMM PF00583 YP_002737528.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002737529.1 identified by match to protein family HMM PF06042 YP_002737530.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_002737531.1 identified by match to protein family HMM PF01148 YP_002737532.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054 YP_002737533.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002737534.1 identified by match to protein family HMM PF00232 YP_002737535.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002737537.1 identified by match to protein family HMM PF00296 YP_002737538.1 identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102 YP_002737539.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002737540.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002737541.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002737542.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_002737543.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_002737544.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002737546.1 identified by match to protein family HMM PF02073 YP_002737547.1 identified by match to protein family HMM PF04226 YP_002737548.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002737549.1 identified by match to protein family HMM PF03051 YP_002737550.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828 YP_002737551.1 identified by match to protein family HMM PF03609 YP_002737552.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830 YP_002737553.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002737554.1 identified by glimmer; putative YP_002737555.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002737556.1 identified by match to protein family HMM PF00860 YP_002737557.1 identified by match to protein family HMM PF02517 YP_002737558.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_002737559.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002737560.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002737561.1 identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498 YP_002737563.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002737564.1 forms a direct contact with the tRNA during translation YP_002737565.1 identified by match to protein family HMM PF00589 YP_002737567.1 identified by match to protein family HMM PF01055 YP_002737568.1 identified by match to protein family HMM PF00255 YP_002737569.1 identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167 YP_002737570.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002737572.1 identified by match to protein family HMM PF02502 YP_002737573.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_002737574.1 identified by match to protein family HMM PF03610 YP_002737575.1 identified by match to protein family HMM PF07470 YP_002737576.1 identified by match to protein family HMM PF03830 YP_002737577.1 identified by match to protein family HMM PF03609 YP_002737578.1 identified by match to protein family HMM PF03613 YP_002737580.1 identified by match to protein family HMM PF07940 YP_002737581.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002737582.1 identified by glimmer; putative YP_002737583.1 identified by glimmer; putative YP_002737585.1 identified by match to protein family HMM PF01381 YP_002737586.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002737587.1 identified by match to protein family HMM TIGR02209 YP_002737588.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793 YP_002737589.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002737590.1 identified by glimmer; putative YP_002737591.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002737592.1 identified by match to protein family HMM PF08388 YP_002737593.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002737594.1 identified by match to protein family HMM PF08903 YP_002737595.1 identified by match to protein family HMM PF00128 YP_002737597.1 identified by glimmer; putative YP_002737598.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002737599.1 identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002737600.1 identified by match to protein family HMM PF02811 YP_002737601.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006 YP_002737602.1 identified by match to protein family HMM TIGR01007 YP_002737603.1 identified by match to protein family HMM PF00534 YP_002737605.1 identified by match to protein family HMM PF00534 YP_002737607.1 identified by match to protein family HMM PF01943 YP_002737608.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002737609.1 identified by match to protein family HMM PF00984; match to protein family HMM PF01210; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002737610.1 identified by glimmer; putative YP_002737611.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002737612.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_002737613.1 identified by match to protein family HMM PF00908 YP_002737614.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_002737615.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002737616.1 identified by match to protein family HMM PF00496 YP_002737617.1 identified by match to protein family HMM PF00754; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002737618.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002737619.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_002737620.1 identified by match to protein family HMM PF06908 YP_002737621.1 identified by match to protein family HMM PF05103 YP_002737622.1 identified by match to protein family HMM PF01170 YP_002737624.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002737625.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002737626.1 identified by match to protein family HMM PF01473 YP_002737627.1 identified by match to protein family HMM PF07690 YP_002737628.1 identified by match to protein family HMM PF01473 YP_002737629.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549 YP_002737630.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240 YP_002737631.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220 YP_002737632.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_002737634.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002737635.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002737638.1 identified by match to protein family HMM PF00089 YP_002737640.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002737641.1 identified by match to protein family HMM TIGR01448 YP_002737642.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227 YP_002737643.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002737645.1 identified by match to protein family HMM PF02674 YP_002737646.1 identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069 YP_002737647.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002737648.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002737649.1 identified by match to protein family HMM PF03595 YP_002737650.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002737651.1 identified by match to protein family HMM PF06115 YP_002737652.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive YP_002737654.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002737655.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965 YP_002737656.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002737657.1 carries the fatty acid chain in fatty acid biosynthesis YP_002737658.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151 YP_002737659.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002737660.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002737661.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002737662.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002737663.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002737664.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002737665.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002737666.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus YP_002737669.1 identified by glimmer; putative YP_002737670.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002737671.1 identified by match to protein family HMM PF03780 YP_002737672.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002737674.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002737675.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002737676.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002737677.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_002737678.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002737679.1 identified by match to protein family HMM PF01501 YP_002737680.1 required for 70S ribosome assembly YP_002737681.1 identified by match to protein family HMM PF03780 YP_002737682.1 identified by match to protein family HMM PF02734 YP_002737683.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002737684.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002737685.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002737688.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_002737691.1 identified by match to protein family HMM PF00005 YP_002737692.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002737695.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02371 YP_002737696.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737697.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002737699.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002737700.1 identified by glimmer; putative YP_002737701.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002737704.1 identified by glimmer; putative YP_002737705.1 identified by glimmer; putative YP_002737706.1 identified by match to protein family HMM PF00480 YP_002737707.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002737709.1 identified by match to protein family HMM PF02255 YP_002737710.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_002737711.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378 YP_002737712.1 identified by match to protein family HMM PF02386 YP_002737713.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002737714.1 identified by match to protein family HMM PF01887 YP_002737715.1 identified by match to protein family HMM PF07155 YP_002737717.1 identified by match to protein family HMM PF00005 YP_002737718.1 identified by match to protein family HMM PF02361 YP_002737719.1 identified by match to protein family HMM PF00588 YP_002737721.1 identified by match to protein family HMM PF01569 YP_002737724.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_002737725.1 identified by glimmer; putative YP_002737726.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002737727.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704 YP_002737728.1 identified by match to protein family HMM PF00746; match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF07501; match to protein family HMM PF07523; match to protein family HMM PF07554; match to protein family HMM TIGR01167 YP_002737729.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002737731.1 identified by match to protein family HMM PF00376 YP_002737732.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653 YP_002737733.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609 YP_002737735.1 identified by match to protein family HMM PF01420 YP_002737736.1 identified by match to protein family HMM PF00589 YP_002737738.1 identified by match to protein family HMM PF01420 YP_002737739.1 identified by match to protein family HMM PF02384; match to protein family HMM PF05175 YP_002737742.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_002737743.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002737744.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002737745.1 identified by glimmer; putative YP_002737746.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002737749.1 identified by match to protein family HMM PF01230 YP_002737750.1 identified by match to protein family HMM PF00005 YP_002737751.1 identified by match to protein family HMM PF05975 YP_002737753.1 identified by match to protein family HMM PF04397 YP_002737754.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002737756.1 identified by match to protein family HMM PF08128; match to protein family HMM TIGR01847 YP_002737757.1 identified by match to protein family HMM TIGR01000 YP_002737758.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193 YP_002737759.1 identified by match to protein family HMM TIGR01847 YP_002737761.1 identified by match to protein family HMM TIGR01847 YP_002737769.1 identified by match to protein family HMM PF02517 YP_002737770.1 identified by match to protein family HMM PF02517 YP_002737771.1 identified by match to protein family HMM PF01636 YP_002737772.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002737773.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002737774.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002737775.1 identified by match to protein family HMM PF04296 YP_002737776.1 identified by match to protein family HMM PF01248 YP_002737777.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002737778.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002737781.1 identified by glimmer; putative YP_002737782.1 identified by match to protein family HMM PF08984 YP_002737783.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282 YP_002737784.1 identified by match to protein family HMM PF08930 YP_002737786.1 identified by glimmer; putative YP_002737787.1 identified by match to protein family HMM PF00583 YP_002737789.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002737791.1 identified by match to protein family HMM PF02661 YP_002737792.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737793.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_002737794.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00830; match to protein family HMM TIGR01995 YP_002737795.1 identified by match to protein family HMM PF00232 YP_002737796.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002737797.1 identified by match to protein family HMM PF00583 YP_002737798.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002737799.1 identified by match to protein family HMM PF03372 YP_002737800.1 identified by match to protein family HMM PF01381 YP_002737801.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002737802.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676 YP_002737803.1 identified by match to protein family HMM TIGR01172 YP_002737804.1 identified by match to protein family HMM PF00583 YP_002737805.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002737806.1 identified by match to protein family HMM PF00636 YP_002737808.1 identified by glimmer; putative YP_002737809.1 identified by glimmer; putative YP_002737810.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002737811.1 identified by match to protein family HMM PF02687 YP_002737812.1 identified by match to protein family HMM PF00005 YP_002737813.1 identified by match to protein family HMM PF02687 YP_002737814.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002737815.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002737816.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_002737817.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002737818.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002737819.1 identified by match to protein family HMM PF00497 YP_002737820.1 identified by match to protein family HMM PF00005 YP_002737821.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644 YP_002737822.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521 YP_002737823.1 identified by match to protein family HMM PF00756 YP_002737824.1 identified by match to protein family HMM PF02388 YP_002737825.1 identified by match to protein family HMM PF02388 YP_002737826.1 identified by match to protein family HMM PF00413 YP_002737827.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002737828.1 identified by match to protein family HMM PF00149 YP_002737829.1 identified by match to protein family HMM PF00497 YP_002737831.1 identified by match to protein family HMM PF00881 YP_002737832.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_002737833.1 identified by match to protein family HMM PF03167 YP_002737834.1 identified by glimmer; putative YP_002737835.1 identified by glimmer; putative YP_002737836.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002737837.1 identified by match to protein family HMM PF05343 YP_002737838.1 identified by match to protein family HMM PF01230 YP_002737839.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737840.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002737841.1 identified by match to protein family HMM PF02557 YP_002737842.1 identified by glimmer; putative YP_002737843.1 binds directly to 23S ribosomal RNA YP_002737844.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002737846.1 identified by match to protein family HMM PF00005 YP_002737847.1 identified by match to protein family HMM PF06182 YP_002737848.1 identified by match to protein family HMM PF06182 YP_002737850.1 identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF06280; match to protein family HMM TIGR01167 YP_002737851.1 identified by match to protein family HMM PF00359 YP_002737853.1 identified by match to protein family HMM PF03611 YP_002737855.1 identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002737856.1 identified by glimmer; putative YP_002737857.1 identified by glimmer; putative YP_002737860.1 identified by match to protein family HMM PF00999 YP_002737861.1 identified by glimmer; putative YP_002737862.1 identified by match to protein family HMM PF03631 YP_002737863.1 identified by match to protein family HMM PF02683 YP_002737864.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002737865.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_002737866.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165 YP_002737867.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580 YP_002737868.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440 YP_002737869.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167 YP_002737870.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553 YP_002737872.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744 YP_002737873.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002737875.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002737876.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156 YP_002737878.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002737879.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002737880.1 identified by match to protein family HMM PF00126 YP_002737881.1 identified by match to protein family HMM PF06014 YP_002737882.1 identified by match to protein family HMM PF00581 YP_002737884.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002737885.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002737887.1 identified by match to protein family HMM TIGR01653 YP_002737888.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_002737889.1 identified by match to protein family HMM PF00005 YP_002737890.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002737891.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002737892.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478 YP_002737893.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002737894.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002737895.1 identified by glimmer; putative YP_002737899.1 identified by match to protein family HMM PF00005 YP_002737900.1 identified by match to protein family HMM PF00497 YP_002737901.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002737903.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002737904.1 identified by match to protein family HMM PF01070; match to protein family HMM TIGR02708 YP_002737905.1 identified by glimmer; putative YP_002737906.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002737907.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693 YP_002737909.1 identified by match to protein family HMM PF00005 YP_002737911.1 identified by match to protein family HMM PF03070 YP_002737912.1 identified by match to protein family HMM TIGR02359 YP_002737913.1 identified by match to protein family HMM PF02110 YP_002737914.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_002737915.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002737916.1 identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698 YP_002737918.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002737919.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720 YP_002737920.1 identified by match to protein family HMM PF00903 YP_002737921.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737922.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737925.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_002737926.1 identified by match to protein family HMM PF00376; match to protein family HMM PF07739; match to protein family HMM PF09278 YP_002737927.1 identified by match to protein family HMM PF00293 YP_002737928.1 identified by match to protein family HMM PF03486; match to protein family HMM TIGR00275 YP_002737929.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002737930.1 identified by match to protein family HMM PF00440 YP_002737931.1 identified by match to protein family HMM PF00383 YP_002737932.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002737933.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002737935.1 identified by match to protein family HMM PF01094 YP_002737936.1 identified by glimmer; putative YP_002737937.1 identified by match to protein family HMM PF02653 YP_002737938.1 identified by match to protein family HMM PF02653 YP_002737939.1 identified by match to protein family HMM PF00005 YP_002737940.1 identified by match to protein family HMM PF00005 YP_002737941.1 identified by match to protein family HMM PF00571 YP_002737942.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_002737943.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673 YP_002737944.1 identified by match to protein family HMM PF02687 YP_002737945.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02003 YP_002737946.1 identified by match to protein family HMM PF03372 YP_002737947.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002737948.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002737949.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group YP_002737950.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002737951.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777 YP_002737952.1 identified by match to protein family HMM PF06265 YP_002737953.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002737954.1 identified by match to protein family HMM PF04892 YP_002737955.1 identified by match to protein family HMM PF00005 YP_002737956.1 identified by match to protein family HMM PF00160 YP_002737958.1 identified by glimmer; putative YP_002737959.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002737961.1 identified by match to protein family HMM PF00561 YP_002737962.1 Essential for efficient processing of 16S rRNA YP_002737963.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002737964.1 identified by match to protein family HMM PF03477 YP_002737968.1 identified by match to protein family HMM PF02632 YP_002737969.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002737970.1 identified by match to protein family HMM TIGR01730 YP_002737971.1 identified by match to protein family HMM PF00005 YP_002737972.1 identified by match to protein family HMM PF02687 YP_002737973.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002737974.1 identified by match to protein family HMM PF03551 YP_002737976.1 identified by match to protein family HMM PF00248 YP_002737978.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002737979.1 identified by match to protein family HMM PF00293 YP_002737980.1 identified by match to protein family HMM PF02896 YP_002737981.1 identified by match to protein family HMM PF06171 YP_002737982.1 identified by match to protein family HMM PF01433 YP_002737983.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002737984.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002737986.1 identified by match to protein family HMM PF01136 YP_002737987.1 unwinds DNA YP_002737988.1 identified by match to protein family HMM PF01098 YP_002737989.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_002737990.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002737991.1 negatively supercoils closed circular double-stranded DNA YP_002737992.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_002737994.1 identified by match to protein family HMM PF05717 YP_002737995.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002737996.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665 YP_002737997.1 identified by match to protein family HMM PF08860 YP_002737998.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002737999.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002738000.1 identified by match to protein family HMM PF08796 YP_002738001.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002738002.1 identified by match to protein family HMM PF00005 YP_002738003.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002738004.1 identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196 YP_002738005.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002738006.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002738007.1 identified by match to protein family HMM PF08002 YP_002738008.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_002738010.1 identified by glimmer; putative YP_002738012.1 identified by glimmer; putative YP_002738013.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002738015.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002738016.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002738017.1 identified by glimmer; putative YP_002738018.1 identified by match to protein family HMM PF05175 YP_002738019.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_002738020.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002738021.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002738022.1 identified by match to protein family HMM PF02608 YP_002738023.1 identified by match to protein family HMM PF00005 YP_002738024.1 identified by match to protein family HMM PF02653 YP_002738025.1 identified by match to protein family HMM PF02653 YP_002738026.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002738027.1 identified by glimmer; putative YP_002738028.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738029.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00665 YP_002738030.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002738031.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002738032.1 identified by glimmer; putative YP_002738033.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002738034.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002738036.1 identified by match to protein family HMM PF06149 YP_002738037.1 identified by match to protein family HMM PF06166 YP_002738038.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_002738040.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002738042.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002738044.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978 YP_002738045.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981 YP_002738046.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979 YP_002738047.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994 YP_002738048.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980 YP_002738049.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943 YP_002738050.1 identified by match to protein family HMM PF01594 YP_002738051.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002738052.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002738053.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427 YP_002738054.1 identified by match to protein family HMM PF01580 YP_002738056.1 identified by match to protein family HMM PF00266 YP_002738057.1 Required for the synthesis of the thiazole moiety YP_002738058.1 identified by match to protein family HMM PF00756 YP_002738060.1 identified by glimmer; putative YP_002738061.1 identified by match to protein family HMM PF02384 YP_002738062.1 identified by match to protein family HMM PF01420 YP_002738064.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550 YP_002738065.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_002738066.1 identified by match to protein family HMM PF01420 YP_002738067.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851 YP_002738069.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_002738070.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue YP_002738071.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. YP_002738072.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_002738073.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002738075.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002738076.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002738077.1 identified by glimmer; putative YP_002738079.1 identified by match to protein family HMM PF09323 YP_002738080.1 identified by match to protein family HMM PF03773 YP_002738081.1 identified by glimmer; putative YP_002738082.1 identified by match to protein family HMM PF00575 YP_002738083.1 identified by match to protein family HMM PF03926 YP_002738084.1 identified by match to protein family HMM PF04024 YP_002738085.1 identified by match to protein family HMM PF00005 YP_002738086.1 identified by match to protein family HMM PF02687 YP_002738087.1 identified by match to protein family HMM PF01988 YP_002738088.1 identified by match to protein family HMM PF00665 YP_002738090.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711 YP_002738091.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738092.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738093.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002738094.1 identified by match to protein family HMM PF03435 YP_002738095.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047 YP_002738096.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_002738097.1 identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381 YP_002738098.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002738099.1 identified by match to protein family HMM PF02517 YP_002738101.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002738102.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002738103.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005 YP_002738104.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473 YP_002738105.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002738106.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002738107.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00112 YP_002738108.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002738109.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA. YP_002738110.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_002738111.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002738112.1 identified by match to protein family HMM PF08020 YP_002738113.1 identified by match to protein family HMM PF06970 YP_002738114.1 identified by match to protein family HMM PF01609 YP_002738115.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_002738116.1 Catalyzes the phosphorylation of UMP to UDP YP_002738117.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002738119.1 identified by match to protein family HMM PF06855 YP_002738120.1 identified by match to protein family HMM PF02562 YP_002738121.1 identified by match to protein family HMM PF00583 YP_002738122.1 identified by glimmer; putative YP_002738123.1 identified by match to protein family HMM PF00583 YP_002738124.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259 YP_002738125.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002738126.1 identified by match to protein family HMM PF00005 YP_002738128.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002738129.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002738130.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002738131.1 identified by match to protein family HMM PF00903 YP_002738132.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) YP_002738133.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits YP_002738134.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01832 YP_002738135.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833 YP_002738136.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002738137.1 identified by match to protein family HMM PF01219 YP_002738138.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002738139.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002738140.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002738141.1 identified by match to protein family HMM PF07690 YP_002738142.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002738143.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002738144.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063 YP_002738145.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002738146.1 with TehA confers resistance to tellurite YP_002738147.1 identified by match to protein family HMM PF06054 YP_002738148.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002738149.1 identified by match to protein family HMM PF01596; match to protein family HMM PF08241 YP_002738150.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein YP_002738153.1 identified by match to protein family HMM PF00300 YP_002738154.1 identified by match to protein family HMM PF04073 YP_002738155.1 identified by match to protein family HMM PF04018 YP_002738156.1 identified by match to protein family HMM PF01183 YP_002738157.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002738158.1 identified by match to protein family HMM PF00293 YP_002738160.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002738161.1 identified by match to protein family HMM PF04394 YP_002738162.1 3'-5' exonuclease of DNA polymerase III YP_002738163.1 identified by match to protein family HMM PF03009 YP_002738164.1 identified by match to protein family HMM PF01710 YP_002738168.1 identified by match to protein family HMM PF02683 YP_002738169.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002738170.1 identified by match to protein family HMM PF00324 YP_002738171.1 identified by match to protein family HMM PF01297 YP_002738172.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002738173.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002738174.1 identified by match to protein family HMM PF04270 YP_002738176.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002738177.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220 YP_002738178.1 identified by match to protein family HMM PF04138 YP_002738179.1 identified by match to protein family HMM PF06177 YP_002738180.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002738181.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002738182.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002738183.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002738184.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002738185.1 identified by match to protein family HMM PF00583 YP_002738186.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002738187.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387 YP_002738188.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_002738189.1 identified by match to protein family HMM PF00583 YP_002738190.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002738193.1 identified by match to protein family HMM PF06207 YP_002738194.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002738196.1 identified by match to protein family HMM PF01497 YP_002738197.1 identified by match to protein family HMM PF01032 YP_002738198.1 identified by match to protein family HMM PF01032 YP_002738199.1 identified by match to protein family HMM PF00005 YP_002738204.1 identified by glimmer; putative YP_002738205.1 identified by match to protein family HMM PF03747 YP_002738206.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147 YP_002738207.1 identified by glimmer; putative YP_002738209.1 identified by match to protein family HMM PF01381 YP_002738210.1 identified by match to protein family HMM PF06414 YP_002738213.1 identified by match to protein family HMM PF03446 YP_002738214.1 identified by glimmer; putative YP_002738216.1 identified by glimmer; putative YP_002738217.1 identified by glimmer; putative YP_002738218.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002738220.1 identified by match to protein family HMM PF01381 YP_002738221.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002738222.1 identified by match to protein family HMM PF01098 YP_002738223.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002738224.1 identified by match to protein family HMM PF04392 YP_002738225.1 identified by match to protein family HMM PF02653 YP_002738226.1 identified by match to protein family HMM PF00005 YP_002738227.1 synthesizes RNA primers at the replication forks YP_002738228.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_002738229.1 identified by match to protein family HMM PF01883 YP_002738230.1 identified by match to protein family HMM PF00534 YP_002738231.1 identified by match to protein family HMM PF00534 YP_002738232.1 identified by match to protein family HMM PF04024 YP_002738234.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002738236.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002738237.1 identified by match to protein family HMM PF00583 YP_002738238.1 identified by match to protein family HMM PF00571; match to protein family HMM PF07085; match to protein family HMM PF08279 YP_002738239.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides YP_002738240.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738241.1 identified by match to protein family HMM PF01609 YP_002738242.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073 YP_002738243.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002738244.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722 YP_002738245.1 modulates transcription in response to the NADH/NAD(+) redox state YP_002738247.1 identified by match to protein family HMM PF08866 YP_002738248.1 identified by match to protein family HMM PF00266 YP_002738249.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002738250.1 identified by match to protein family HMM PF01928 YP_002738251.1 identified by match to protein family HMM PF04607 YP_002738252.1 catalyzes the phosphorylation of NAD to NADP YP_002738253.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005 YP_002738254.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002738255.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002738256.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002738257.1 identified by match to protein family HMM PF04327 YP_002738258.1 involved in the peptidyltransferase reaction during translation YP_002738259.1 identified by glimmer; putative YP_002738261.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002738262.1 identified by match to protein family HMM PF02588 YP_002738263.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002738264.1 identified by match to protein family HMM PF00216 YP_002738265.1 identified by match to protein family HMM PF00005 YP_002738266.1 identified by match to protein family HMM TIGR01716 YP_002738267.1 identified by match to protein family HMM PF07690 YP_002738268.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002738269.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104 YP_002738271.1 identified by match to protein family HMM PF00171 YP_002738272.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_002738273.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002738274.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092 YP_002738275.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_002738276.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002738277.1 identified by match to protein family HMM PF07997 YP_002738278.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002738279.1 identified by match to protein family HMM PF00589 YP_002738280.1 identified by glimmer; putative YP_002738281.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002738282.1 identified by match to protein family HMM TIGR02774 YP_002738283.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785 YP_002738285.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168 YP_002738286.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167 YP_002738287.1 identified by glimmer; putative YP_002738289.1 identified by match to protein family HMM PF06970 YP_002738290.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002738294.1 identified by match to protein family HMM PF02517 YP_002738295.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02920 YP_002738296.1 identified by match to protein family HMM PF09035 YP_002738297.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281 YP_002738298.1 identified by glimmer; putative YP_002738299.1 identified by match to protein family HMM PF01381 YP_002738300.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231 YP_002738301.1 regulates the transcription of tet(M) by attenuation YP_002738303.1 identified by match to protein family HMM PF00877 YP_002738307.1 identified by match to protein family HMM PF07275 YP_002738309.1 identified by match to protein family HMM PF01381; match to protein family HMM PF02486 YP_002738310.1 identified by match to protein family HMM PF01580 YP_002738311.1 identified by match to protein family HMM PF06125 YP_002738312.1 identified by match to protein family HMM PF06125 YP_002738316.1 identified by match to protein family HMM PF02534 YP_002738321.1 identified by match to protein family HMM PF01551; match to protein family HMM PF05257 YP_002738324.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF02384; match to protein family HMM PF04851 YP_002738327.1 identified by glimmer; putative YP_002738333.1 identified by match to protein family HMM PF01381 YP_002738334.1 identified by match to protein family HMM PF06414 YP_002738335.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_002738336.1 identified by match to protein family HMM PF00817 YP_002738339.1 identified by glimmer; putative YP_002738340.1 identified by match to protein family HMM PF05713 YP_002738341.1 identified by match to protein family HMM PF03432 YP_002738342.1 identified by match to protein family HMM PF01381 YP_002738343.1 identified by match to protein family HMM PF00589 YP_002738344.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_002738345.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002738346.1 identified by match to protein family HMM PF00654; match to protein family HMM PF02080 YP_002738347.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS YP_002738348.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545 YP_002738349.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350 YP_002738350.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain YP_002738351.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002738352.1 identified by match to protein family HMM PF00676 YP_002738353.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002738354.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002738355.1 identified by match to protein family HMM PF00293 YP_002738356.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002738358.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254 YP_002738359.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609 YP_002738360.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002738361.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363 YP_002738362.1 identified by glimmer; putative YP_002738363.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_002738364.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002738365.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_002738366.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002738367.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002738368.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002738369.1 identified by glimmer; putative YP_002738370.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_002738371.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853 YP_002738372.1 identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823 YP_002738373.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123 YP_002738374.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_002738375.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP YP_002738376.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate YP_002738377.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization YP_002738378.1 identified by glimmer; putative YP_002738379.1 identified by match to protein family HMM PF01609 YP_002738380.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738382.1 identified by match to protein family HMM PF00359 YP_002738384.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002738385.1 identified by match to protein family HMM PF00149 YP_002738386.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002738387.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_002738388.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478 YP_002738389.1 identified by match to protein family HMM PF00348 YP_002738390.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002738391.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002738392.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002738394.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002738396.1 identified by match to protein family HMM PF01226 YP_002738397.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076 YP_002738398.1 negatively supercoils closed circular double-stranded DNA YP_002738399.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH YP_002738400.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885 YP_002738401.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002738403.1 identified by match to protein family HMM PF00753 YP_002738404.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229 YP_002738405.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002738406.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002738407.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_002738408.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114 YP_002738409.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine. YP_002738412.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279 YP_002738413.1 identified by match to protein family HMM PF00293 YP_002738414.1 identified by match to protein family HMM PF00583 YP_002738416.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002738417.1 identified by match to protein family HMM PF02517 YP_002738418.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002738419.1 identified by match to protein family HMM PF00005 YP_002738420.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002738421.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064 YP_002738422.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002738423.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002738424.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168 YP_002738425.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002738426.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306 YP_002738430.1 identified by match to protein family HMM PF06961 YP_002738431.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002738432.1 identified by match to protein family HMM PF04237 YP_002738433.1 identified by match to protein family HMM PF03932 YP_002738434.1 identified by match to protein family HMM PF04304 YP_002738435.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_002738436.1 identified by match to protein family HMM PF04087 YP_002738438.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002738439.1 identified by match to protein family HMM PF00483 YP_002738440.1 identified by match to protein family HMM PF00892 YP_002738441.1 identified by match to protein family HMM PF01633; match to protein family HMM PF01636 YP_002738442.1 identified by match to protein family HMM PF08240 YP_002738443.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002738444.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002738445.1 required for phosphorylcholine incorporation in teichoic and lipoteichoic acids; identified by match to protein family HMM PF04991 YP_002738446.1 identified by match to protein family HMM PF04991 YP_002738447.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002738448.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002738449.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002738450.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_002738451.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083 YP_002738452.1 identified by match to protein family HMM PF02620 YP_002738453.1 identified by glimmer; putative YP_002738454.1 identified by glimmer; putative YP_002738455.1 identified by match to protein family HMM PF00005 YP_002738456.1 putative metalloprotease YP_002738457.1 identified by match to protein family HMM PF04011 YP_002738458.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002738459.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002738460.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959 YP_002738461.1 identified by match to protein family HMM PF04297; match to protein family HMM PF04967; match to protein family HMM PF08281 YP_002738463.1 identified by match to protein family HMM PF01966 YP_002738464.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002738465.1 identified by match to protein family HMM PF02037 YP_002738466.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002738467.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002738468.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002738469.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805 YP_002738470.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_002738471.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002738472.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002738475.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002738477.1 identified by match to protein family HMM PF00005 YP_002738478.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609 YP_002738479.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738481.1 identified by match to protein family HMM PF00701 YP_002738482.1 identified by match to protein family HMM PF00383; match to protein family HMM TIGR01354 YP_002738483.1 identified by match to protein family HMM PF04608 YP_002738485.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002738486.1 identified by match to protein family HMM PF00528 YP_002738487.1 identified by match to protein family HMM PF00528 YP_002738488.1 identified by match to protein family HMM PF00496 YP_002738490.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002738493.1 identified by match to protein family HMM PF08843 YP_002738495.1 identified by match to protein family HMM PF02517 YP_002738496.1 identified by glimmer; putative YP_002738500.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002738501.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002738502.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002738503.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002738504.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002738505.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401 YP_002738507.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002738508.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002738509.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_002738512.1 identified by match to protein family HMM PF00535 YP_002738513.1 identified by match to protein family HMM PF00534 YP_002738514.1 identified by match to protein family HMM PF04991 YP_002738515.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002738516.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002738517.1 identified by match to protein family HMM PF01202 YP_002738518.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002738519.1 identified by match to protein family HMM PF06133 YP_002738520.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_002738521.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002738522.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002738523.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002738524.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_002738527.1 identified by match to protein family HMM PF00005 YP_002738528.1 converts 1,4-alpha-D-glucans to maltodextrin YP_002738529.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002738530.1 identified by match to protein family HMM PF04525 YP_002738532.1 identified by match to protein family HMM PF01547 YP_002738533.1 identified by match to protein family HMM PF00528 YP_002738534.1 identified by match to protein family HMM PF00528 YP_002738535.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_002738536.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002738538.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252 YP_002738539.1 identified by match to protein family HMM PF00392 YP_002738540.1 identified by match to protein family HMM PF00497 YP_002738541.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_002738542.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002738543.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002738544.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002738545.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002738546.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136 YP_002738548.1 identified by match to protein family HMM PF01189 YP_002738549.1 identified by match to protein family HMM PF00459 YP_002738550.1 identified by match to protein family HMM PF05256 YP_002738551.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_002738552.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906 YP_002738553.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460 YP_002738554.1 identified by match to protein family HMM PF01643 YP_002738555.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002738557.1 identified by match to protein family HMM PF06103 YP_002738558.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002738559.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_002738560.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002738561.1 identified by match to protein family HMM PF01182 YP_002738562.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002738563.1 identified by match to protein family HMM PF01473 YP_002738564.1 identified by match to protein family HMM PF00583 YP_002738565.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002738566.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_002738568.1 identified by match to protein family HMM PF01381 YP_002738569.1 identified by glimmer; putative YP_002738570.1 identified by glimmer; putative YP_002738571.1 identified by glimmer; putative YP_002738572.1 identified by match to protein family HMM PF01136 YP_002738573.1 identified by match to protein family HMM PF01555 YP_002738575.1 identified by match to protein family HMM PF00165 YP_002738576.1 identified by match to protein family HMM PF00005 YP_002738577.1 identified by match to protein family HMM PF00005 YP_002738578.1 identified by match to protein family HMM TIGR02185 YP_002738579.1 identified by match to protein family HMM PF02361 YP_002738580.1 identified by match to protein family HMM PF00005 YP_002738581.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002738582.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop YP_002738583.1 identified by glimmer; putative YP_002738584.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF05717 YP_002738586.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002738587.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002738588.1 identified by match to protein family HMM PF00892 YP_002738589.1 identified by match to protein family HMM PF00144 YP_002738591.1 identified by match to protein family HMM PF00657 YP_002738592.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002738593.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002738594.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186 YP_002738595.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292 YP_002738597.1 identified by match to protein family HMM PF00005 YP_002738598.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002738599.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002738600.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_002738601.1 identified by match to protein family HMM PF00583 YP_002738602.1 identified by match to protein family HMM PF08876 YP_002738603.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002738604.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_002738605.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_002738606.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992 YP_002738608.1 identified by match to protein family HMM PF02424 YP_002738609.1 identified by match to protein family HMM PF03358 YP_002738610.1 identified by match to protein family HMM PF03358 YP_002738611.1 identified by match to protein family HMM PF05979 YP_002738612.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002738613.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002738614.1 identified by glimmer; putative YP_002738615.1 identified by glimmer; putative YP_002738616.1 identified by match to protein family HMM PF00248 YP_002738617.1 identified by match to protein family HMM PF01522 YP_002738619.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408 YP_002738620.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002738621.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738623.1 identified by glimmer; putative YP_002738624.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002738626.1 identified by match to protein family HMM PF00230 YP_002738627.1 identified by glimmer; putative YP_002738628.1 identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167 YP_002738630.1 identified by glimmer; putative YP_002738633.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738634.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738635.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002738636.1 identified by match to protein family HMM TIGR01295 YP_002738637.1 identified by match to protein family HMM PF00497 YP_002738638.1 identified by match to protein family HMM PF00005 YP_002738639.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002738640.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_002738641.1 identified by match to protein family HMM PF01594 YP_002738643.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002738644.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002738645.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002738646.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002738647.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002738648.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002738649.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002738650.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0 YP_002738651.1 identified by match to protein family HMM PF00665 YP_002738653.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002738654.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002738655.1 identified by match to protein family HMM PF00583 YP_002738656.1 identified by match to protein family HMM PF00583 YP_002738657.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002738659.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455 YP_002738660.1 identified by match to protein family HMM PF00155 YP_002738661.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002738662.1 identified by match to protein family HMM PF00005 YP_002738663.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609 YP_002738664.1 identified by match to protein family HMM PF00496 YP_002738665.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023 YP_002738666.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine YP_002738667.1 identified by match to protein family HMM PF05532 YP_002738668.1 identified by glimmer; putative YP_002738669.1 identified by glimmer; putative YP_002738671.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002738672.1 identified by match to protein family HMM PF01541 YP_002738673.1 identified by match to protein family HMM PF05175 YP_002738674.1 identified by match to protein family HMM PF00575 YP_002738675.1 identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002738676.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002738677.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002738678.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002738679.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002738680.1 identified by match to protein family HMM PF00903 YP_002738681.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002738682.1 identified by match to protein family HMM PF03413 YP_002738683.1 identified by glimmer; putative YP_002738684.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_002738685.1 identified by match to protein family HMM PF03883 YP_002738688.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002738689.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_002738690.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002738691.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002738692.1 identified by match to protein family HMM PF00005 YP_002738693.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_002738694.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002738695.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762 YP_002738696.1 identified by match to protein family HMM PF06619 YP_002738697.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002738698.1 identified by match to protein family HMM PF07949 YP_002738699.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159 YP_002738700.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_002738701.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647 YP_002738702.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002738703.1 identified by match to protein family HMM PF03668 YP_002738704.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002738705.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002738706.1 binds and unfolds substrates as part of the ClpXP protease YP_002738708.1 identified by match to protein family HMM PF00186 YP_002738709.1 identified by match to protein family HMM PF00210 YP_002738710.1 identified by match to protein family HMM PF01183; match to protein family HMM PF01473 YP_002738711.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002738712.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446 YP_002738713.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002738714.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002738715.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002738717.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002738718.1 identified by match to protein family HMM PF00857 YP_002738719.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_002738720.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002738721.1 identified by match to protein family HMM PF07690 YP_002738722.1 Involved in disulfide oxidoreductase activity and electron transport YP_002738723.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353 YP_002738724.1 identified by match to protein family HMM PF07685 YP_002738725.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321 YP_002738728.1 identified by glimmer; putative YP_002738730.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002738731.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002738732.1 identified by match to protein family HMM PF07690 YP_002738733.1 identified by glimmer; putative YP_002738735.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002738736.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002738739.1 identified by match to protein family HMM PF00535 YP_002738740.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002738741.1 identified by glimmer; putative YP_002738742.1 identified by match to protein family HMM PF01266 YP_002738743.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002738744.1 identified by match to protein family HMM PF04816 YP_002738746.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738747.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002738748.1 identified by match to protein family HMM PF00834 YP_002738749.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_002738750.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848 YP_002738751.1 identified by match to protein family HMM PF00359 YP_002738752.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002738753.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494 YP_002738754.1 identified by match to protein family HMM PF01553 YP_002738755.1 identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779 YP_002738756.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002738759.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002738760.1 identified by match to protein family HMM PF02518 YP_002738761.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002738764.1 identified by match to protein family HMM PF02082 YP_002738765.1 identified by match to protein family HMM PF00149 YP_002738766.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023 YP_002738771.1 identified by glimmer; putative YP_002738772.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002738773.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002738774.1 identified by match to protein family HMM PF00753 YP_002738775.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649 YP_002738776.1 identified by match to protein family HMM PF00005 YP_002738777.1 identified by match to protein family HMM PF00950 YP_002738778.1 identified by match to protein family HMM PF01297 YP_002738779.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002738780.1 identified by match to protein family HMM PF02687 YP_002738781.1 identified by match to protein family HMM PF00005 YP_002738783.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002738786.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002738788.1 identified by match to protein family HMM PF05103 YP_002738789.1 identified by match to protein family HMM PF01479 YP_002738790.1 identified by match to protein family HMM PF02325 YP_002738791.1 identified by match to protein family HMM PF04472 YP_002738792.1 identified by match to protein family HMM TIGR00044 YP_002738793.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002738794.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174 YP_002738795.1 identified by match to protein family HMM TIGR02206 YP_002738796.1 identified by match to protein family HMM PF00293 YP_002738797.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002738798.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002738799.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002738800.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002738801.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002738802.1 identified by match to protein family HMM PF00480 YP_002738803.1 identified by match to protein family HMM PF00701 YP_002738804.1 identified by match to protein family HMM PF04854 YP_002738805.1 identified by glimmer; putative YP_002738806.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002738807.1 identified by match to protein family HMM PF00528 YP_002738808.1 identified by match to protein family HMM PF00528 YP_002738809.1 identified by match to protein family HMM PF01547 YP_002738810.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826 YP_002738811.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002738812.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447 YP_002738813.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973 YP_002738814.1 identified by match to protein family HMM PF00528 YP_002738815.1 identified by match to protein family HMM PF00528 YP_002738816.1 identified by match to protein family HMM PF01547 YP_002738817.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002738818.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167 YP_002738820.1 identified by match to protein family HMM PF05448 YP_002738821.1 catalyzes branch migration in Holliday junction intermediates YP_002738822.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002738823.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002738824.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002738825.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002738826.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002738827.1 identified by glimmer; putative YP_002738828.1 identified by match to protein family HMM PF00005 YP_002738833.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002738834.1 identified by match to protein family HMM PF00881 YP_002738835.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_002738836.1 identified by match to protein family HMM PF07261 YP_002738837.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002738838.1 identified by match to protein family HMM PF00392 YP_002738839.1 identified by match to protein family HMM PF00005 YP_002738842.1 identified by match to protein family HMM PF00005 YP_002738844.1 identified by match to protein family HMM PF09335 YP_002738845.1 identified by match to protein family HMM PF00480 YP_002738846.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996 YP_002738848.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_002738849.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002738850.1 identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835 YP_002738852.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01609 YP_002738853.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002738855.1 identified by match to protein family HMM PF06738 YP_002738856.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793 YP_002738857.1 identified by match to protein family HMM PF00481 YP_002738858.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563 YP_002738859.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002738860.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002738861.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002738862.1 Essential for recycling GMP and indirectly, cGMP YP_002738863.1 identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319 YP_002738865.1 identified by match to protein family HMM PF05636 YP_002738866.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002738867.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002738868.1 identified by match to protein family HMM PF00857 YP_002738869.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488 YP_002738870.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002738871.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253 YP_002738872.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_002738873.1 identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668 YP_002738874.1 identified by match to protein family HMM PF01544 YP_002738875.1 identified by match to protein family HMM PF00924 YP_002738876.1 identified by match to protein family HMM PF06081 YP_002738877.1 identified by match to protein family HMM PF01047 YP_002738879.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002738880.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_002738881.1 identified by match to protein family HMM PF00230 YP_002738883.1 identified by match to protein family HMM PF01061 YP_002738884.1 identified by match to protein family HMM PF00005 YP_002738885.1 identified by match to protein family HMM PF01022 YP_002738886.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181 YP_002738887.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002738888.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002738889.1 identified by match to protein family HMM PF00293 YP_002738890.1 identified by match to protein family HMM PF02163 YP_002738892.1 identified by match to protein family HMM PF03681 YP_002738895.1 identified by match to protein family HMM PF00004 YP_002738896.1 identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322 YP_002738897.1 identified by match to protein family HMM PF00528 YP_002738898.1 identified by match to protein family HMM PF00528 YP_002738899.1 identified by match to protein family HMM PF01547 YP_002738900.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002738901.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280 YP_002738902.1 identified by match to protein family HMM PF04226 YP_002738905.1 identified by match to protein family HMM PF03780 YP_002738906.1 identified by match to protein family HMM PF05532 YP_002738907.1 identified by glimmer; putative YP_002738908.1 identified by match to protein family HMM PF01925 YP_002738909.1 identified by match to protein family HMM PF03781 YP_002738911.1 identified by match to protein family HMM PF02302 YP_002738913.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002738914.1 identified by match to protein family HMM PF00480 YP_002738915.1 identified by match to protein family HMM PF00583 YP_002738916.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750 YP_002738917.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114 YP_002738918.1 identified by glimmer; putative YP_002738919.1 identified by glimmer; putative YP_002738920.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002738921.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002738922.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_002738923.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_002738924.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002738925.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002738926.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002738928.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002738929.1 identified by match to protein family HMM PF02308 YP_002738930.1 identified by match to protein family HMM PF00528 YP_002738931.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_002738933.1 identified by match to protein family HMM PF08975 YP_002738935.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168 YP_002738936.1 identified by match to protein family HMM PF01041 YP_002738937.1 identified by match to protein family HMM PF02397 YP_002738938.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002738939.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002738940.1 identified by glimmer; putative YP_002738941.1 identified by glimmer; putative YP_002738942.1 identified by glimmer; putative YP_002738943.1 identified by glimmer; putative YP_002738944.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633 YP_002738945.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_002738946.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_002738947.1 identified by match to protein family HMM PF04556 YP_002738948.1 identified by match to protein family HMM PF01555 YP_002738949.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_002738950.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002738951.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism YP_002738952.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002738953.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002738954.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002738955.1 identified by match to protein family HMM PF00376 YP_002738956.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297 YP_002738957.1 identified by match to protein family HMM PF00440 YP_002738958.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002738959.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF01609 YP_002738960.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069 YP_002738961.1 identified by match to protein family HMM PF00005 YP_002738962.1 identified by match to protein family HMM PF07366 YP_002738963.1 identified by match to protein family HMM PF01047 YP_002738964.1 identified by match to protein family HMM PF08957 YP_002738965.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107 YP_002738966.1 identified by glimmer; putative YP_002738967.1 identified by match to protein family HMM PF01032 YP_002738968.1 identified by match to protein family HMM PF01032 YP_002738969.1 identified by match to protein family HMM PF00005 YP_002738970.1 identified by match to protein family HMM PF01497 YP_002738971.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278 YP_002738972.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093 YP_002738973.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer YP_002738974.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB YP_002738975.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002738976.1 identified by match to protein family HMM PF00571 YP_002738977.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002738978.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002738979.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002738980.1 identified by match to protein family HMM PF03672 YP_002738981.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002738982.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992 YP_002738983.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404 YP_002738984.1 identified by match to protein family HMM PF00005 YP_002738985.1 identified by glimmer; putative YP_002738986.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002738987.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002738988.1 identified by match to protein family HMM PF00528 YP_002738989.1 identified by match to protein family HMM PF00528 YP_002738990.1 identified by match to protein family HMM PF00496 YP_002738992.1 identified by match to protein family HMM PF04932 YP_002738993.1 identified by match to protein family HMM PF00128 YP_002738995.1 identified by match to protein family HMM PF00528 YP_002738996.1 identified by match to protein family HMM PF00528 YP_002738997.1 identified by match to protein family HMM PF01547 YP_002738998.1 identified by match to protein family HMM PF02065 YP_002738999.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311 YP_002739000.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002739001.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479 YP_002739002.1 identified by match to protein family HMM PF01636 YP_002739003.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002739004.1 identified by match to protein family HMM PF04167 YP_002739005.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002739006.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002739007.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002739008.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002739009.1 identified by match to protein family HMM PF01588 YP_002739010.1 identified by match to protein family HMM PF00085 YP_002739012.1 identified by match to protein family HMM PF01473 YP_002739014.1 identified by match to protein family HMM PF04397 YP_002739015.1 identified by match to protein family HMM PF01569 YP_002739017.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002739018.1 identified by match to protein family HMM PF01289 YP_002739031.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510 YP_002739032.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002739033.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002739034.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200 YP_002739035.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350 YP_002739036.1 identified by match to protein family HMM PF00583 YP_002739037.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150 YP_002739039.1 identified by match to protein family HMM PF01381 YP_002739041.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654 YP_002739042.1 identified by match to protein family HMM PF00005 YP_002739044.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002739045.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002739046.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002739047.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002739048.1 identified by match to protein family HMM PF01223 YP_002739050.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002739053.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002739054.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095 YP_002739055.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002739056.1 identified by glimmer; putative YP_002739057.1 identified by match to protein family HMM PF01027 YP_002739058.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002739059.1 catalyzes the hydrolysis of acylphosphate YP_002739060.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site YP_002739061.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493 YP_002739062.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784 YP_002739063.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743 YP_002739064.1 identified by match to protein family HMM PF01336; match to protein family HMM PF01966 YP_002739065.1 identified by match to protein family HMM PF02646 YP_002739066.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378 YP_002739067.1 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163 YP_002739068.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002739069.1 identified by glimmer; putative YP_002739070.1 identified by glimmer; putative YP_002739071.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002739072.1 identified by glimmer; putative YP_002739073.1 identified by match to protein family HMM PF00005 YP_002739075.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334 YP_002739076.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002739077.1 identified by match to protein family HMM PF00746; match to protein family HMM PF07564; match to protein family HMM TIGR01167 YP_002739078.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002739079.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002739081.1 identified by match to protein family HMM PF00582 YP_002739082.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002739083.1 identified by match to protein family HMM PF00710 YP_002739085.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481 YP_002739086.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002739087.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002739088.1 identified by match to protein family HMM PF01061 YP_002739089.1 identified by match to protein family HMM PF00005 YP_002739093.1 Modulates Rho-dependent transcription termination YP_002739094.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002739095.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_002739096.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074 YP_002739097.1 identified by match to protein family HMM PF00849 YP_002739098.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002739099.1 identified by match to protein family HMM PF02687 YP_002739100.1 identified by glimmer; putative YP_002739101.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01710 YP_002739102.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002739103.1 identified by match to protein family HMM PF03600; match to protein family HMM PF07158 YP_002739105.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002739106.1 identified by match to protein family HMM PF00232 YP_002739107.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_002739108.1 identified by match to protein family HMM PF02302 YP_002739109.1 identified by match to protein family HMM PF02255 YP_002739110.1 identified by match to protein family HMM PF00465 YP_002739111.1 identified by match to protein family HMM PF02493 YP_002739112.1 identified by match to protein family HMM PF01451 YP_002739113.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002739114.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002739116.1 identified by match to protein family HMM PF00874; match to protein family HMM PF08279 YP_002739117.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways YP_002739118.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_002739119.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002739120.1 identified by match to protein family HMM PF00359 YP_002739121.1 identified by match to protein family HMM PF02302 YP_002739122.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002739124.1 identified by match to protein family HMM PF01424 YP_002739125.1 identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592 YP_002739126.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002739128.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002739130.1 identified by glimmer; putative YP_002739131.1 identified by glimmer; putative YP_002739135.1 identified by match to protein family HMM TIGR02532 YP_002739136.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002739137.1 identified by match to protein family HMM PF00482 YP_002739138.1 identified by match to protein family HMM PF00437 YP_002739139.1 identified by match to protein family HMM PF06279 YP_002739140.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002739141.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_002739142.1 identified by match to protein family HMM PF01757 YP_002739143.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_002739144.1 identified by match to protein family HMM PF06161 YP_002739145.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_002739146.1 identified by match to protein family HMM PF06993 YP_002739147.1 identified by glimmer; putative YP_002739148.1 identified by match to protein family HMM PF01476 YP_002739149.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549 YP_002739150.1 identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR00797 YP_002739151.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002739154.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002739155.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002739157.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722 YP_002739158.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002739160.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002739161.1 This protein performs the mismatch recognition step during the DNA repair process YP_002739162.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529 YP_002739163.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002739164.1 identified by match to protein family HMM PF01609 YP_002739165.1 identified by match to protein family HMM PF06172 YP_002739166.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002739167.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002739169.1 identified by glimmer; putative YP_002739170.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138 YP_002739171.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974 YP_002739172.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002739173.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135 YP_002739175.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002739176.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099 YP_002739177.1 identified by glimmer; putative YP_002739178.1 identified by match to protein family HMM PF01694 YP_002739179.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727 YP_002739180.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_002739181.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503 YP_002739182.1 identified by match to protein family HMM PF00892 YP_002739183.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912 YP_002739184.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002739185.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525 YP_002739187.1 identified by match to protein family HMM PF08241 YP_002739189.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002739190.1 amylomaltase; acts to release glucose from maltodextrins YP_002739191.1 identified by match to protein family HMM PF01547 YP_002739192.1 identified by match to protein family HMM PF00528; match to protein family HMM PF05154 YP_002739193.1 identified by match to protein family HMM PF00528 YP_002739195.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002739197.1 identified by match to protein family HMM PF02588 YP_002739198.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002739200.1 identified by match to protein family HMM PF02517 YP_002739203.1 identified by match to protein family HMM PF01381 YP_002739206.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002739207.1 identified by match to protein family HMM PF07690 YP_002739208.1 identified by match to protein family HMM TIGR01716 YP_002739209.1 identified by match to protein family HMM PF01883 YP_002739210.1 identified by glimmer; putative YP_002739211.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002739212.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002739213.1 identified by match to protein family HMM PF00456 YP_002739214.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002739215.1 identified by match to protein family HMM PF02302 YP_002739216.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874 YP_002739217.1 identified by match to protein family HMM PF01145 YP_002739219.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002739220.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002739221.1 identified by match to protein family HMM PF00728 YP_002739222.1 identified by match to protein family HMM PF00480 YP_002739223.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748 YP_002739224.1 identified by match to protein family HMM PF06824 YP_002739225.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180 YP_002739227.1 identified by glimmer; putative YP_002739228.1 catalyzes the degradation of arginine to citruline and ammonia YP_002739229.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_002739230.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002739231.1 identified by match to protein family HMM PF03606 YP_002739232.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887 YP_002739234.1 identified by match to protein family HMM PF01145 YP_002739235.1 identified by match to protein family HMM PF00465 YP_002739236.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_002739237.1 identified by match to protein family HMM PF00754; match to protein family HMM PF08306; match to protein family HMM PF08307 YP_002739239.1 identified by match to protein family HMM PF03613 YP_002739240.1 identified by match to protein family HMM PF03609 YP_002739241.1 identified by match to protein family HMM PF03830 YP_002739242.1 identified by match to protein family HMM PF03610 YP_002739243.1 identified by match to protein family HMM PF05025 YP_002739244.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002739245.1 identified by match to protein family HMM PF00370 YP_002739246.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002739247.1 identified by match to protein family HMM PF01297; match to protein family HMM PF09223 YP_002739248.1 identified by match to protein family HMM PF00950 YP_002739249.1 identified by match to protein family HMM PF00005 YP_002739250.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279 YP_002739252.1 identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918 YP_002739253.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_002739254.1 identified by match to protein family HMM PF03062 YP_002739255.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_002739257.1 identified by match to protein family HMM PF07690 YP_002739258.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_002739259.1 identified by glimmer; putative YP_002739260.1 identified by glimmer; putative YP_002739261.1 identified by glimmer; putative YP_002739262.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002739263.1 identified by match to protein family HMM PF01266 YP_002739264.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002739265.1 identified by match to protein family HMM PF05043 YP_002739266.1 identified by glimmer; putative YP_002739267.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_002739268.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002739269.1 identified by match to protein family HMM PF01473; match to protein family HMM PF04650; match to protein family HMM PF05062; match to protein family HMM TIGR01168 YP_002739270.1 identified by match to protein family HMM PF04140 YP_002739271.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002739272.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002739273.1 identified by glimmer; putative YP_002739275.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_002739276.1 identified by match to protein family HMM PF05848 YP_002739277.1 identified by match to protein family HMM PF00005 YP_002739278.1 identified by match to protein family HMM PF09084 YP_002739279.1 identified by match to protein family HMM PF00528 YP_002739281.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460 YP_002739282.1 identified by match to protein family HMM PF06257 YP_002739283.1 unwinds double stranded DNA YP_002739284.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002739285.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272 YP_002739286.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741 YP_002739288.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002739289.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002739290.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139 YP_002739291.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift YP_002739292.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; identified by match to protein family HMM PF05717 YP_002739293.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002739294.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002739295.1 identified by match to protein family HMM PF05257 YP_002739296.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426 YP_002739297.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002739298.1 identified by match to protein family HMM PF02361 YP_002739299.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene YP_002739300.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene YP_002739301.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002739303.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002739304.1 identified by match to protein family HMM PF05193 YP_002739305.1 identified by match to protein family HMM TIGR02988 YP_002739306.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002739307.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002739308.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002739309.1 identified by match to protein family HMM PF00005 YP_002739313.1 identified by match to protein family HMM PF00440 YP_002739314.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_002739315.1 identified by match to protein family HMM PF02518 YP_002739316.1 identified by match to protein family HMM PF03047 YP_002739317.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002739318.1 identified by match to protein family HMM PF00089 YP_002739319.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180