-- dump date 20140620_085321 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002741522.1 225860013 7686582 197..1558 1 NC_012469.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1558 dnaA 7686582 dnaA Streptococcus pneumoniae Taiwan19F-14 chromosomal replication initiation protein YP_002741522.1 197 D 487213 CDS YP_002741523.1 225860014 7686368 1717..2853 1 NC_012469.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2853 dnaN 7686368 dnaN Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III subunit beta YP_002741523.1 1717 D 487213 CDS YP_002741524.1 225860015 7685742 2918..3112 1 NC_012469.1 identified by match to protein family HMM PF06107; hypothetical protein 3112 7685742 SPT_0003 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741524.1 2918 D 487213 CDS YP_002741525.1 225860016 7687256 complement(3563..3982) 1 NC_012469.1 phage protein 3982 7687256 SPT_0004 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741525.1 3563 R 487213 CDS YP_002741526.1 225860017 7686281 4106..4297 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 4297 7686281 SPT_0005 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741526.1 4106 D 487213 CDS YP_002741527.1 225860018 7687346 complement(4601..4852) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 4852 7687346 SPT_0006 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741527.1 4601 R 487213 CDS YP_002741528.1 225860019 7686026 complement(4839..5180) 1 NC_012469.1 phage replication protein 5180 7686026 SPT_0007 Streptococcus pneumoniae Taiwan19F-14 phage replication protein YP_002741528.1 4839 R 487213 CDS YP_002741529.1 225860020 7686106 complement(5231..5356) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 5356 7686106 SPT_0008 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741529.1 5231 R 487213 CDS YP_002741530.1 225860021 7687142 complement(5560..6084) 1 NC_012469.1 phage protein 6084 7687142 SPT_0009 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741530.1 5560 R 487213 CDS YP_002741531.1 225860022 7686735 complement(6177..6374) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 6374 7686735 SPT_0010 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741531.1 6177 R 487213 CDS YP_002741532.1 225860023 7687305 complement(6694..8259) 1 NC_012469.1 identified by match to protein family HMM PF08706; match to protein family HMM TIGR01613; DNA primase 8259 7687305 SPT_0011 Streptococcus pneumoniae Taiwan19F-14 DNA primase YP_002741532.1 6694 R 487213 CDS YP_002741533.1 225860024 7686857 complement(8228..9088) 1 NC_012469.1 identified by match to protein family HMM PF08708; phage protein 9088 7686857 SPT_0012 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741533.1 8228 R 487213 CDS YP_002741534.1 225860025 7686247 complement(9085..9357) 1 NC_012469.1 identified by similarity to GB:AAV62370.1; hypothetical protein 9357 7686247 SPT_0013 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741534.1 9085 R 487213 CDS YP_002741535.1 225860026 7685649 complement(9350..9691) 1 NC_012469.1 phage protein 9691 7685649 SPT_0014 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741535.1 9350 R 487213 CDS YP_002741536.1 225860027 7686127 complement(9672..9848) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 9848 7686127 SPT_0015 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741536.1 9672 R 487213 CDS YP_002741537.1 225860028 7685964 complement(9962..10177) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 10177 7685964 SPT_0016 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741537.1 9962 R 487213 CDS YP_002741538.1 225860029 7685811 complement(10170..10436) 1 NC_012469.1 hypothetical protein 10436 7685811 SPT_0017 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741538.1 10170 R 487213 CDS YP_002741539.1 225860030 7686404 complement(10454..10594) 1 NC_012469.1 hypothetical protein 10594 7686404 SPT_0018 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741539.1 10454 R 487213 CDS YP_002741540.1 225860031 7685863 complement(10606..11106) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 11106 7685863 SPT_0019 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741540.1 10606 R 487213 CDS YP_002741541.1 225860032 7686712 complement(11103..11243) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 11243 7686712 SPT_0020 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741541.1 11103 R 487213 CDS YP_002741542.1 225860033 7687308 complement(11644..11790) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 11790 7687308 SPT_0021 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741542.1 11644 R 487213 CDS YP_002741543.1 225860034 7687368 complement(11794..12222) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 12222 7687368 SPT_0022 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741543.1 11794 R 487213 CDS YP_002741544.1 225860035 7685799 complement(12376..12549) 1 NC_012469.1 hypothetical protein 12549 7685799 SPT_0023 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741544.1 12376 R 487213 CDS YP_002741545.1 225860036 7687298 complement(12788..13036) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 13036 7687298 SPT_0024 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741545.1 12788 R 487213 CDS YP_002741546.1 225860037 7686744 complement(13048..13653) 1 NC_012469.1 hypothetical protein 13653 7686744 SPT_0025 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741546.1 13048 R 487213 CDS YP_002741547.1 225860038 7685243 complement(13675..13983) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 13983 7685243 SPT_0026 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741547.1 13675 R 487213 CDS YP_002741548.1 225860039 7687199 14245..15591 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 15591 7687199 SPT_0027 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002741548.1 14245 D 487213 CDS YP_002741549.1 225860040 7685269 complement(15835..15987) 1 NC_012469.1 transcription regulator 15987 7685269 SPT_0028 Streptococcus pneumoniae Taiwan19F-14 transcription regulator YP_002741549.1 15835 R 487213 CDS YP_002741550.1 225860041 7685509 16230..16946 1 NC_012469.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381; cI repressor 16946 7685509 SPT_0029 Streptococcus pneumoniae Taiwan19F-14 cI repressor YP_002741550.1 16230 D 487213 CDS YP_002741551.1 225860042 7686202 16965..17633 1 NC_012469.1 LIM domain protein 17633 7686202 SPT_0030 Streptococcus pneumoniae Taiwan19F-14 LIM domain protein YP_002741551.1 16965 D 487213 CDS YP_002741552.1 225860043 7687146 17772..18440 1 NC_012469.1 identified by match to protein family HMM PF02661; Fic protein family 18440 7687146 SPT_0031 Streptococcus pneumoniae Taiwan19F-14 Fic protein family YP_002741552.1 17772 D 487213 CDS YP_002741553.1 225860044 7686722 complement(18904..19362) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 19362 7686722 SPT_0032 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741553.1 18904 R 487213 CDS YP_002741554.1 225860045 7685218 19720..19842 1 NC_012469.1 hypothetical protein 19842 7685218 SPT_0033 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741554.1 19720 D 487213 CDS YP_002741555.1 225860046 7687058 20266..20502 1 NC_012469.1 identified by similarity to GB:CAG39798.1; hypothetical protein 20502 7687058 SPT_0034 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741555.1 20266 D 487213 CDS YP_002741556.1 225860047 7686452 20785..21090 1 NC_012469.1 replication protein 21090 7686452 SPT_0035 Streptococcus pneumoniae Taiwan19F-14 replication protein YP_002741556.1 20785 D 487213 CDS YP_002741557.1 225860048 7686229 21195..21755 1 NC_012469.1 putative DNA damage inducible protein 21755 7686229 SPT_0036 Streptococcus pneumoniae Taiwan19F-14 putative DNA damage inducible protein YP_002741557.1 21195 D 487213 CDS YP_002741558.1 225860049 7686635 22191..23357 1 NC_012469.1 identified by match to protein family HMM PF00589; integrase 23357 7686635 SPT_0037 Streptococcus pneumoniae Taiwan19F-14 integrase YP_002741558.1 22191 D 487213 CDS YP_002741559.1 225860050 7686449 23477..24592 1 NC_012469.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 24592 ychF 7686449 ychF Streptococcus pneumoniae Taiwan19F-14 GTP-dependent nucleic acid-binding protein EngD YP_002741559.1 23477 D 487213 CDS YP_002741560.1 225860051 7686018 24663..25232 1 NC_012469.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 25232 pth 7686018 pth Streptococcus pneumoniae Taiwan19F-14 peptidyl-tRNA hydrolase YP_002741560.1 24663 D 487213 CDS YP_002741561.1 225860052 7686609 25233..28742 1 NC_012469.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 28742 mfd 7686609 mfd Streptococcus pneumoniae Taiwan19F-14 transcription-repair coupling factor YP_002741561.1 25233 D 487213 CDS YP_002741562.1 225860053 7687103 28800..29066 1 NC_012469.1 identified by match to protein family HMM PF01479; ribosome-associated heat shock protein implicated in the recycling of the 50S subunit 29066 7687103 SPT_0041 Streptococcus pneumoniae Taiwan19F-14 ribosome-associated heat shock protein implicated in the recycling of the 50S subunit YP_002741562.1 28800 D 487213 CDS YP_002741563.1 225860054 7686137 29059..29427 1 NC_012469.1 identified by match to protein family HMM PF04977; septum formation initiator 29427 7686137 SPT_0042 Streptococcus pneumoniae Taiwan19F-14 septum formation initiator YP_002741563.1 29059 D 487213 CDS YP_002741564.1 225860055 7685652 29432..29554 1 NC_012469.1 hypothetical protein 29554 7685652 SPT_0043 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741564.1 29432 D 487213 CDS YP_002741565.1 225860056 7687007 29547..30815 1 NC_012469.1 beta-lactamase class A 30815 7687007 SPT_0044 Streptococcus pneumoniae Taiwan19F-14 beta-lactamase class A YP_002741565.1 29547 D 487213 CDS YP_002741566.1 225860057 7687387 30812..32089 1 NC_012469.1 identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) 32089 7687387 SPT_0045 Streptococcus pneumoniae Taiwan19F-14 tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) YP_002741566.1 30812 D 487213 CDS YP_002741567.1 225860058 7685907 32093..32635 1 NC_012469.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 32635 hpt 7685907 hpt Streptococcus pneumoniae Taiwan19F-14 hypoxanthine phosphoribosyltransferase YP_002741567.1 32093 D 487213 CDS YP_002741568.1 225860059 7687010 32651..34609 1 NC_012469.1 identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; putative Cell division protease FtsH homolog 34609 7687010 SPT_0047 Streptococcus pneumoniae Taiwan19F-14 putative Cell division protease FtsH homolog YP_002741568.1 32651 D 487213 CDS YP_002741569.1 225860060 7686461 34731..35210 1 NC_012469.1 competence-specific global transcription modulator 35210 7686461 SPT_0048 Streptococcus pneumoniae Taiwan19F-14 competence-specific global transcription modulator YP_002741569.1 34731 D 487213 CDS YP_002741570.1 225860061 7687118 42067..42303 1 NC_012469.1 hypothetical protein 42303 7687118 SPT_0058 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741570.1 42067 D 487213 CDS YP_002741571.1 225860062 7685482 42492..43820 1 NC_012469.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 43820 purA 7685482 purA Streptococcus pneumoniae Taiwan19F-14 adenylosuccinate synthetase YP_002741571.1 42492 D 487213 CDS YP_002741572.1 225860063 7685516 44021..44488 1 NC_012469.1 identified by match to protein family HMM PF00383; tRNA-specific adenosine deaminase 44488 7685516 SPT_0060 Streptococcus pneumoniae Taiwan19F-14 tRNA-specific adenosine deaminase YP_002741572.1 44021 D 487213 CDS YP_002741573.1 225860064 7685543 44675..45118 1 NC_012469.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 45118 dut 7685543 dut Streptococcus pneumoniae Taiwan19F-14 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002741573.1 44675 D 487213 CDS YP_002741574.1 225860065 7686375 45078..45635 1 NC_012469.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 45635 7686375 SPT_0062 Streptococcus pneumoniae Taiwan19F-14 phosphoglycerate mutase family protein YP_002741574.1 45078 D 487213 CDS YP_002741575.1 225860066 7686982 45748..47010 1 NC_012469.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 47010 radA 7686982 radA Streptococcus pneumoniae Taiwan19F-14 DNA repair protein RadA YP_002741575.1 45748 D 487213 CDS YP_002741576.1 225860067 7685506 47083..47580 1 NC_012469.1 identified by match to protein family HMM PF00484; carbonate dehydratase 47580 7685506 SPT_0064 Streptococcus pneumoniae Taiwan19F-14 carbonate dehydratase YP_002741576.1 47083 D 487213 CDS YP_002741577.1 225860068 7686314 47605..48420 1 NC_012469.1 hypothetical protein 48420 7686314 SPT_0065 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741577.1 47605 D 487213 CDS YP_002741578.1 225860069 7687035 48565..49533 1 NC_012469.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 49533 7687035 SPT_0066 Streptococcus pneumoniae Taiwan19F-14 ribose-phosphate pyrophosphokinase YP_002741578.1 48565 D 487213 CDS YP_002741579.1 225860070 7686214 complement(50077..50310) 1 NC_012469.1 hypothetical protein 50310 7686214 SPT_0067 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741579.1 50077 R 487213 CDS YP_002741580.1 225860071 7686932 complement(50268..50594) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 50594 7686932 SPT_0068 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741580.1 50268 R 487213 CDS YP_002741581.1 225860072 7686640 complement(50634..50948) 1 NC_012469.1 hypothetical protein 50948 7686640 SPT_0069 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741581.1 50634 R 487213 CDS YP_002741582.1 225860073 7687123 51240..53873 1 NC_012469.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 53873 7687123 SPT_0070 Streptococcus pneumoniae Taiwan19F-14 DNA polymerase I YP_002741582.1 51240 D 487213 CDS YP_002741583.1 225860074 7685535 53958..54395 1 NC_012469.1 identified by match to protein family HMM PF02629; CoA binding protein 54395 7685535 SPT_0071 Streptococcus pneumoniae Taiwan19F-14 CoA binding protein YP_002741583.1 53958 D 487213 CDS YP_002741584.1 225860075 7686024 complement(54578..55588) 1 NC_012469.1 identified by match to protein family HMM PF03601; hypothetical protein 55588 7686024 SPT_0072 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741584.1 54578 R 487213 CDS YP_002741585.1 225860076 7686532 55737..56906 1 NC_012469.1 catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 56906 7686532 SPT_0073 Streptococcus pneumoniae Taiwan19F-14 aromatic amino acid aminotransferase YP_002741585.1 55737 D 487213 CDS YP_002741586.1 225860077 7685958 56903..57673 1 NC_012469.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 57673 recO 7685958 recO Streptococcus pneumoniae Taiwan19F-14 DNA repair protein RecO YP_002741586.1 56903 D 487213 CDS YP_002741587.1 225860078 7685340 57670..58662 1 NC_012469.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 58662 plsX 7685340 plsX Streptococcus pneumoniae Taiwan19F-14 putative glycerol-3-phosphate acyltransferase PlsX YP_002741587.1 57670 D 487213 CDS YP_002741588.1 225860079 7687227 58668..58901 1 NC_012469.1 hypothetical protein 58901 7687227 SPT_0076 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741588.1 58668 D 487213 CDS YP_002741589.1 225860080 7685436 58944..59237 1 NC_012469.1 mobile genetic element 59237 7685436 SPT_0077 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002741589.1 58944 D 487213 CDS YP_002741590.1 225860081 7685407 59440..59670 1 NC_012469.1 identified by match to protein family HMM TIGR01847; hypothetical protein 59670 7685407 SPT_0078 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741590.1 59440 D 487213 CDS YP_002741591.1 225860082 7687245 59673..59798 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 59798 7687245 SPT_0079 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741591.1 59673 D 487213 CDS YP_002741592.1 225860083 7687293 60385..62538 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193; transport/processing ATP-binding protein ComA 62538 7687293 SPT_0080 Streptococcus pneumoniae Taiwan19F-14 transport/processing ATP-binding protein ComA YP_002741592.1 60385 D 487213 CDS YP_002741593.1 225860084 7686484 62551..63900 1 NC_012469.1 identified by match to protein family HMM TIGR01000; transport protein ComB 63900 7686484 SPT_0081 Streptococcus pneumoniae Taiwan19F-14 transport protein ComB YP_002741593.1 62551 D 487213 CDS YP_002741594.1 225860085 7685246 64070..64777 1 NC_012469.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 64777 purC 7685246 purC Streptococcus pneumoniae Taiwan19F-14 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002741594.1 64070 D 487213 CDS YP_002741595.1 225860086 7686710 64788..64922 1 NC_012469.1 phosphoribosylaminoimidazole-succinocarboxamide synthase (saicar synthetase) 64922 7686710 SPT_0083 Streptococcus pneumoniae Taiwan19F-14 phosphoribosylaminoimidazole-succinocarboxamide synthase (saicar synthetase) YP_002741595.1 64788 D 487213 CDS YP_002741596.1 225860087 7686001 64979..68704 1 NC_012469.1 identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857; phosphoribosylformylglycinamidine synthase 68704 7686001 SPT_0084 Streptococcus pneumoniae Taiwan19F-14 phosphoribosylformylglycinamidine synthase YP_002741596.1 64979 D 487213 CDS YP_002741597.1 225860088 7686585 68797..70239 1 NC_012469.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 70239 purF 7686585 purF Streptococcus pneumoniae Taiwan19F-14 amidophosphoribosyltransferase YP_002741597.1 68797 D 487213 CDS YP_002741598.1 225860089 7685670 70276..71298 1 NC_012469.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 71298 purM 7685670 purM Streptococcus pneumoniae Taiwan19F-14 phosphoribosylaminoimidazole synthetase YP_002741598.1 70276 D 487213 CDS YP_002741599.1 225860090 7686775 71295..71840 1 NC_012469.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 71840 purN 7686775 purN Streptococcus pneumoniae Taiwan19F-14 phosphoribosylglycinamide formyltransferase YP_002741599.1 71295 D 487213 CDS YP_002741600.1 225860091 7685852 71924..72433 1 NC_012469.1 identified by match to protein family HMM PF04892; teicoplanin resistance protein 72433 7685852 SPT_0088 Streptococcus pneumoniae Taiwan19F-14 teicoplanin resistance protein YP_002741600.1 71924 D 487213 CDS YP_002741601.1 225860092 7687172 72458..74005 1 NC_012469.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 74005 purH 7687172 purH Streptococcus pneumoniae Taiwan19F-14 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002741601.1 72458 D 487213 CDS YP_002741602.1 225860093 7686186 74127..75389 1 NC_012469.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 75389 purD 7686186 purD Streptococcus pneumoniae Taiwan19F-14 phosphoribosylamine--glycine ligase YP_002741602.1 74127 D 487213 CDS YP_002741603.1 225860094 7685489 75792..76280 1 NC_012469.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 76280 purE 7685489 purE Streptococcus pneumoniae Taiwan19F-14 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_002741603.1 75792 D 487213 CDS YP_002741604.1 225860095 7686297 76267..77358 1 NC_012469.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 77358 purK 7686297 purK Streptococcus pneumoniae Taiwan19F-14 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002741604.1 76267 D 487213 CDS YP_002741605.1 225860096 7685889 77368..77595 1 NC_012469.1 hypothetical protein 77595 7685889 SPT_0093 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741605.1 77368 D 487213 CDS YP_002741606.1 225860097 7685878 77658..78956 1 NC_012469.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 78956 purB 7685878 purB Streptococcus pneumoniae Taiwan19F-14 adenylosuccinate lyase YP_002741606.1 77658 D 487213 CDS YP_002741607.1 225860098 7686763 complement(79011..82949) 1 NC_012469.1 identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-N-acetylhexosaminidase 82949 7686763 SPT_0095 Streptococcus pneumoniae Taiwan19F-14 beta-N-acetylhexosaminidase YP_002741607.1 79011 R 487213 CDS YP_002741608.1 225860099 7686832 complement(83265..84008) 1 NC_012469.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 84008 7686832 SPT_0096 Streptococcus pneumoniae Taiwan19F-14 GntR family transcriptional regulator YP_002741608.1 83265 R 487213 CDS YP_002741609.1 225860100 7685731 84329..86116 1 NC_012469.1 identified by match to protein family HMM PF01301; match to protein family HMM PF02449; beta-galactosidase (Lactase) 86116 7685731 SPT_0097 Streptococcus pneumoniae Taiwan19F-14 beta-galactosidase (Lactase) YP_002741609.1 84329 D 487213 CDS YP_002741610.1 225860101 7685415 86113..86589 1 NC_012469.1 identified by match to protein family HMM PF03830; phosphotransferase system sugar-specific eiib component 86589 7685415 SPT_0098 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific eiib component YP_002741610.1 86113 D 487213 CDS YP_002741611.1 225860102 7686413 86617..87522 1 NC_012469.1 identified by match to protein family HMM PF03609; PTS system, IIC component 87522 7686413 SPT_0099 Streptococcus pneumoniae Taiwan19F-14 PTS system, IIC component YP_002741611.1 86617 D 487213 CDS YP_002741612.1 225860103 7685697 87509..88324 1 NC_012469.1 identified by match to protein family HMM PF03613; PTS system, IID component 88324 7685697 SPT_0100 Streptococcus pneumoniae Taiwan19F-14 PTS system, IID component YP_002741612.1 87509 D 487213 CDS YP_002741613.1 225860104 7686509 88331..88735 1 NC_012469.1 identified by match to protein family HMM PF03610; phosphotransferase system sugar-specific EII component 88735 7686509 SPT_0101 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002741613.1 88331 D 487213 CDS YP_002741614.1 225860105 7686294 89029..90195 1 NC_012469.1 identified by match to protein family HMM PF01380; putative tagatose-6-phosphate ketose/aldose isomerase 90195 7686294 SPT_0102 Streptococcus pneumoniae Taiwan19F-14 putative tagatose-6-phosphate ketose/aldose isomerase YP_002741614.1 89029 D 487213 CDS YP_002741615.1 225860106 7685477 90311..91348 1 NC_012469.1 identified by match to protein family HMM PF01263; aldose 1-epimerase 91348 7685477 SPT_0103 Streptococcus pneumoniae Taiwan19F-14 aldose 1-epimerase YP_002741615.1 90311 D 487213 CDS YP_002741616.1 225860107 7686114 91555..92409 1 NC_012469.1 identified by match to protein family HMM PF00903; glyoxalase family protein 92409 7686114 SPT_0104 Streptococcus pneumoniae Taiwan19F-14 glyoxalase family protein YP_002741616.1 91555 D 487213 CDS YP_002741617.1 225860108 7686249 92559..92816 1 NC_012469.1 identified by match to protein family HMM PF02583; hypothetical protein 92816 7686249 SPT_0105 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741617.1 92559 D 487213 CDS YP_002741618.1 225860109 7685532 complement(92858..93220) 1 NC_012469.1 chlorohydrolase 93220 7685532 SPT_0106 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002741618.1 92858 R 487213 CDS YP_002741619.1 225860110 7686038 complement(93274..93570) 1 NC_012469.1 identified by match to protein family HMM PF00581; hypothetical protein 93570 7686038 SPT_0107 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741619.1 93274 R 487213 CDS YP_002741620.1 225860111 7687379 complement(93560..93679) 1 NC_012469.1 coenzyme A disulfide reductase 93679 7687379 SPT_0108 Streptococcus pneumoniae Taiwan19F-14 coenzyme A disulfide reductase YP_002741620.1 93560 R 487213 CDS YP_002741621.1 225860112 7686468 93791..94555 1 NC_012469.1 identified by match to protein family HMM PF01048; phosphorylase, Pnp/Udp family 94555 7686468 SPT_0109 Streptococcus pneumoniae Taiwan19F-14 phosphorylase, Pnp/Udp family YP_002741621.1 93791 D 487213 CDS YP_002741622.1 225860113 7685687 complement(94795..94947) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 94947 7685687 SPT_0110 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741622.1 94795 R 487213 CDS YP_002741623.1 225860114 7686826 95165..96544 1 NC_012469.1 identified by match to protein family HMM PF02386; Trk transporter membrane-spanning protein - K+ transport 96544 7686826 SPT_0111 Streptococcus pneumoniae Taiwan19F-14 Trk transporter membrane-spanning protein - K+ transport YP_002741623.1 95165 D 487213 CDS YP_002741624.1 225860115 7686003 96558..97223 1 NC_012469.1 identified by match to protein family HMM PF02254; potassium uptake protein, Trk family 97223 7686003 SPT_0112 Streptococcus pneumoniae Taiwan19F-14 potassium uptake protein, Trk family YP_002741624.1 96558 D 487213 CDS YP_002741625.1 225860116 7686602 97358..97516 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 97516 7686602 SPT_0113 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741625.1 97358 D 487213 CDS YP_002741626.1 225860117 7685211 98710..101739 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 101739 7685211 SPT_0116 Streptococcus pneumoniae Taiwan19F-14 cell wall surface anchor family protein YP_002741626.1 98710 D 487213 CDS YP_002741627.1 225860118 7686566 101906..102604 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator SaeR 102604 7686566 SPT_0117 Streptococcus pneumoniae Taiwan19F-14 response regulator SaeR YP_002741627.1 101906 D 487213 CDS YP_002741628.1 225860119 7685748 102601..103653 1 NC_012469.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 103653 7685748 SPT_0118 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002741628.1 102601 D 487213 CDS YP_002741629.1 225860120 7685951 103848..104459 1 NC_012469.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 104459 rpsD 7685951 rpsD Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S4 YP_002741629.1 103848 D 487213 CDS YP_002741630.1 225860121 7685770 105225..105485 1 NC_012469.1 hypothetical protein 105485 7685770 SPT_0120 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741630.1 105225 D 487213 CDS YP_002741631.1 225860122 7687207 105439..105660 1 NC_012469.1 hypothetical protein 105660 7687207 SPT_0121 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741631.1 105439 D 487213 CDS YP_002741632.1 225860123 7686279 105949..106908 1 NC_012469.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 106908 7686279 SPT_0122 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter permease YP_002741632.1 105949 D 487213 CDS YP_002741633.1 225860124 7685911 106922..107845 1 NC_012469.1 identified by match to protein family HMM PF00528; protein LplC 107845 7685911 SPT_0123 Streptococcus pneumoniae Taiwan19F-14 protein LplC YP_002741633.1 106922 D 487213 CDS YP_002741634.1 225860125 7687280 108103..109578 1 NC_012469.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 109578 7687280 SPT_0124 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002741634.1 108103 D 487213 CDS YP_002741635.1 225860126 7686267 109850..110836 1 NC_012469.1 identified by match to protein family HMM PF00581; hypothetical protein 110836 7686267 SPT_0125 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741635.1 109850 D 487213 CDS YP_002741636.1 225860127 7687340 111111..111971 1 NC_012469.1 hypothetical protein 111971 7687340 SPT_0126 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741636.1 111111 D 487213 CDS YP_002741637.1 225860128 7685669 112358..112522 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 112522 7685669 SPT_0127 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741637.1 112358 D 487213 CDS YP_002741638.1 225860129 7686798 113248..114594 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 114594 7686798 SPT_0128 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002741638.1 113248 D 487213 CDS YP_002741639.1 225860130 7687094 115516..115641 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 115641 7687094 SPT_0129 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741639.1 115516 D 487213 CDS YP_002741640.1 225860131 7686481 115666..115863 1 NC_012469.1 macrolide export ATP-binding/permease protein MacB 115863 7686481 SPT_0130 Streptococcus pneumoniae Taiwan19F-14 macrolide export ATP-binding/permease protein MacB YP_002741640.1 115666 D 487213 CDS YP_002741641.1 225860132 7686780 complement(116100..117164) 1 NC_012469.1 hypothetical protein 117164 7686780 SPT_0131 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741641.1 116100 R 487213 CDS YP_002741642.1 225860133 7686035 complement(117227..118138) 1 NC_012469.1 hypothetical protein 118138 7686035 SPT_0132 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741642.1 117227 R 487213 CDS YP_002741643.1 225860134 7685205 complement(118131..118724) 1 NC_012469.1 hypothetical protein 118724 7685205 SPT_0133 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741643.1 118131 R 487213 CDS YP_002741644.1 225860135 7687049 complement(118711..119037) 1 NC_012469.1 identified by match to protein family HMM PF03551; transcriptional regulator, PadR family 119037 7687049 SPT_0134 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, PadR family YP_002741644.1 118711 R 487213 CDS YP_002741645.1 225860136 7687270 complement(119176..120342) 1 NC_012469.1 identified by match to protein family HMM PF07690; cyanate permease 120342 7687270 SPT_0135 Streptococcus pneumoniae Taiwan19F-14 cyanate permease YP_002741645.1 119176 R 487213 CDS YP_002741646.1 225860137 7686691 120493..121557 1 NC_012469.1 identified by match to protein family HMM PF00535; glycosyl transferase 121557 7686691 SPT_0136 Streptococcus pneumoniae Taiwan19F-14 glycosyl transferase YP_002741646.1 120493 D 487213 CDS YP_002741647.1 225860138 7685864 121599..123449 1 NC_012469.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; CapD protein, required for the biosynthesis of type 1 capsular polysaccharide 123449 7685864 SPT_0137 Streptococcus pneumoniae Taiwan19F-14 CapD protein, required for the biosynthesis of type 1 capsular polysaccharide YP_002741647.1 121599 D 487213 CDS YP_002741648.1 225860139 7686633 complement(123799..124431) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphoglycolate phosphatase 124431 7686633 SPT_0138 Streptococcus pneumoniae Taiwan19F-14 phosphoglycolate phosphatase YP_002741648.1 123799 R 487213 CDS YP_002741649.1 225860140 7685203 complement(124453..125325) 1 NC_012469.1 identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase, iron-sulfur-dependent, alpha subunit 125325 sdaAA 7685203 sdaAA Streptococcus pneumoniae Taiwan19F-14 L-serine dehydratase, iron-sulfur-dependent, alpha subunit YP_002741649.1 124453 R 487213 CDS YP_002741650.1 225860141 7686118 complement(125334..126005) 1 NC_012469.1 identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase, iron-sulfur-dependent, beta subunit 126005 sdaAB 7686118 sdaAB Streptococcus pneumoniae Taiwan19F-14 L-serine dehydratase, iron-sulfur-dependent, beta subunit YP_002741650.1 125334 R 487213 CDS YP_002741651.1 225860142 7686193 126247..126834 1 NC_012469.1 identified by match to protein family HMM PF01476; LysM domain protein 126834 7686193 SPT_0141 Streptococcus pneumoniae Taiwan19F-14 LysM domain protein YP_002741651.1 126247 D 487213 CDS YP_002741652.1 225860143 7686860 complement(126886..127206) 1 NC_012469.1 hypothetical protein 127206 7686860 SPT_0142 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741652.1 126886 R 487213 CDS YP_002741653.1 225860144 7686852 127658..127906 1 NC_012469.1 identified by match to protein family HMM TIGR01653; bacteriocin, lactococcin 972 family 127906 7686852 SPT_0143 Streptococcus pneumoniae Taiwan19F-14 bacteriocin, lactococcin 972 family YP_002741653.1 127658 D 487213 CDS YP_002741654.1 225860145 7686039 127961..130069 1 NC_012469.1 identified by match to protein family HMM TIGR01654; amino acid ABC transporter permease 130069 7686039 SPT_0144 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter permease YP_002741654.1 127961 D 487213 CDS YP_002741655.1 225860146 7686946 130066..130707 1 NC_012469.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 130707 7686946 SPT_0145 Streptococcus pneumoniae Taiwan19F-14 macrolide export ATP-binding/permease protein MacB YP_002741655.1 130066 D 487213 CDS YP_002741656.1 225860147 7686573 130914..131720 1 NC_012469.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 131720 7686573 SPT_0146 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter substrate-binding protein YP_002741656.1 130914 D 487213 CDS YP_002741657.1 225860148 7687194 131737..132156 1 NC_012469.1 identified by match to protein family HMM PF00764; argininosuccinate synthase (Citrulline--aspartateligase) 132156 7687194 SPT_0147 Streptococcus pneumoniae Taiwan19F-14 argininosuccinate synthase (Citrulline--aspartateligase) YP_002741657.1 131737 D 487213 CDS YP_002741658.1 225860149 7686275 complement(132446..132766) 1 NC_012469.1 hypothetical protein 132766 7686275 SPT_0148 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741658.1 132446 R 487213 CDS YP_002741659.1 225860150 7685713 133525..133893 1 NC_012469.1 hypothetical protein 133893 7685713 SPT_0149 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741659.1 133525 D 487213 CDS YP_002741660.1 225860151 7685842 complement(134293..135156) 1 NC_012469.1 identified by match to protein family HMM PF01381; helix-turn-helix domain protein 135156 7685842 SPT_0150 Streptococcus pneumoniae Taiwan19F-14 helix-turn-helix domain protein YP_002741660.1 134293 R 487213 CDS YP_002741661.1 225860152 7686765 135724..135960 1 NC_012469.1 hypothetical protein 135960 7686765 SPT_0151 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741661.1 135724 D 487213 CDS YP_002741662.1 225860153 7685880 136258..136434 1 NC_012469.1 hypothetical protein 136434 7685880 SPT_0152 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741662.1 136258 D 487213 CDS YP_002741663.1 225860154 7686648 136588..136800 1 NC_012469.1 hypothetical protein 136800 7686648 SPT_0153 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741663.1 136588 D 487213 CDS YP_002741664.1 225860155 7685798 137216..137578 1 NC_012469.1 hypothetical protein 137578 7685798 SPT_0154 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741664.1 137216 D 487213 CDS YP_002741665.1 225860156 7685665 137961..139019 1 NC_012469.1 hypothetical protein 139019 7685665 SPT_0155 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741665.1 137961 D 487213 CDS YP_002741666.1 225860157 7685313 139335..140312 1 NC_012469.1 hypothetical protein 140312 7685313 SPT_0156 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741666.1 139335 D 487213 CDS YP_002741667.1 225860158 7687398 140689..141063 1 NC_012469.1 hypothetical protein 141063 7687398 SPT_0157 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741667.1 140689 D 487213 CDS YP_002741668.1 225860159 7685376 141070..141252 1 NC_012469.1 hypothetical protein 141252 7685376 SPT_0158 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741668.1 141070 D 487213 CDS YP_002741669.1 225860160 7686486 141271..142173 1 NC_012469.1 hypothetical protein 142173 7686486 SPT_0159 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741669.1 141271 D 487213 CDS YP_002741670.1 225860161 7686964 142229..142582 1 NC_012469.1 hypothetical protein 142582 7686964 SPT_0160 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741670.1 142229 D 487213 CDS YP_002741671.1 225860162 7686340 142579..143307 1 NC_012469.1 hypothetical protein 143307 7686340 SPT_0161 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741671.1 142579 D 487213 CDS YP_002741672.1 225860163 7686747 144442..144681 1 NC_012469.1 hypothetical protein 144681 7686747 SPT_0162 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741672.1 144442 D 487213 CDS YP_002741673.1 225860164 7687400 145231..147405 1 NC_012469.1 identified by match to protein family HMM PF01473; pneumococcal surface protein A 147405 7687400 SPT_0163 Streptococcus pneumoniae Taiwan19F-14 pneumococcal surface protein A YP_002741673.1 145231 D 487213 CDS YP_002741674.1 225860165 7686972 147658..147783 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 147783 7686972 SPT_0164 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741674.1 147658 D 487213 CDS YP_002741675.1 225860166 7686674 147806..148927 1 NC_012469.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 148927 mnmA 7686674 mnmA Streptococcus pneumoniae Taiwan19F-14 tRNA-specific 2-thiouridylase MnmA YP_002741675.1 147806 D 487213 CDS YP_002741676.1 225860167 7686169 149068..149523 1 NC_012469.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 149523 7686169 SPT_0166 Streptococcus pneumoniae Taiwan19F-14 MutT/nudix family protein YP_002741676.1 149068 D 487213 CDS YP_002741677.1 225860168 7686637 149533..151446 1 NC_012469.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 151446 gidA 7686637 gidA Streptococcus pneumoniae Taiwan19F-14 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_002741677.1 149533 D 487213 CDS YP_002741678.1 225860169 7686232 complement(151578..151727) 1 NC_012469.1 chlorohydrolase 151727 7686232 SPT_0168 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002741678.1 151578 R 487213 CDS YP_002741679.1 225860170 7686082 complement(151799..153478) 1 NC_012469.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; metallo-beta-lactamase superfamily protein domain protein 153478 7686082 SPT_0169 Streptococcus pneumoniae Taiwan19F-14 metallo-beta-lactamase superfamily protein domain protein YP_002741679.1 151799 R 487213 CDS YP_002741680.1 225860171 7685658 complement(153480..153713) 1 NC_012469.1 identified by match to protein family HMM PF07288; hypothetical protein 153713 7685658 SPT_0170 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741680.1 153480 R 487213 CDS YP_002741681.1 225860172 7687001 complement(154039..154284) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 154284 7687001 SPT_0171 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741681.1 154039 R 487213 CDS YP_002741682.1 225860173 7686617 complement(154531..154683) 1 NC_012469.1 identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein 154683 7686617 SPT_0172 Streptococcus pneumoniae Taiwan19F-14 bacteriocin-type signal sequence domain protein YP_002741682.1 154531 R 487213 CDS YP_002741683.1 225860174 7686259 complement(154685..154870) 1 NC_012469.1 hypothetical protein 154870 7686259 SPT_0173 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741683.1 154685 R 487213 CDS YP_002741684.1 225860175 7686125 155048..155731 1 NC_012469.1 identified by match to protein family HMM PF00814; glycoprotein endopeptidase 155731 7686125 SPT_0174 Streptococcus pneumoniae Taiwan19F-14 glycoprotein endopeptidase YP_002741684.1 155048 D 487213 CDS YP_002741685.1 225860176 7686316 155728..156165 1 NC_012469.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 156165 rimI 7686316 rimI Streptococcus pneumoniae Taiwan19F-14 ribosomal-protein-alanine acetyltransferase YP_002741685.1 155728 D 487213 CDS YP_002741686.1 225860177 7686986 156155..157165 1 NC_012469.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 157165 7686986 SPT_0176 Streptococcus pneumoniae Taiwan19F-14 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002741686.1 156155 D 487213 CDS YP_002741687.1 225860178 7687209 160948..161823 1 NC_012469.1 identified by match to protein family HMM PF00535; glycosyl transferase, family 2 161823 7687209 SPT_0181 Streptococcus pneumoniae Taiwan19F-14 glycosyl transferase, family 2 YP_002741687.1 160948 D 487213 CDS YP_002741688.1 225860179 7685463 161910..163526 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 163526 7685463 SPT_0182 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002741688.1 161910 D 487213 CDS YP_002741689.1 225860180 7686463 163546..163701 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 163701 7686463 SPT_0183 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741689.1 163546 D 487213 CDS YP_002741690.1 225860181 7687020 164078..164302 1 NC_012469.1 hypothetical protein 164302 7687020 SPT_0184 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741690.1 164078 D 487213 CDS YP_002741691.1 225860182 7687391 164853..165053 1 NC_012469.1 hypothetical protein 165053 7687391 SPT_0185 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741691.1 164853 D 487213 CDS YP_002741692.1 225860183 7686331 166632..167495 1 NC_012469.1 identified by match to protein family HMM TIGR01716; MutR 167495 7686331 SPT_0188 Streptococcus pneumoniae Taiwan19F-14 MutR YP_002741692.1 166632 D 487213 CDS YP_002741693.1 225860184 7687165 167786..167983 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 167983 7687165 SPT_0189 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741693.1 167786 D 487213 CDS YP_002741694.1 225860185 7686292 168051..168716 1 NC_012469.1 identified by match to protein family HMM PF02517; caax amino protease family 168716 7686292 SPT_0190 Streptococcus pneumoniae Taiwan19F-14 caax amino protease family YP_002741694.1 168051 D 487213 CDS YP_002741695.1 225860186 7687393 168788..170014 1 NC_012469.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 170014 7687393 SPT_0191 Streptococcus pneumoniae Taiwan19F-14 transporter, major facilitator family protein YP_002741695.1 168788 D 487213 CDS YP_002741696.1 225860187 7686248 complement(170290..170487) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 170487 7686248 SPT_0192 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741696.1 170290 R 487213 CDS YP_002741697.1 225860188 7685894 170558..171214 1 NC_012469.1 identified by match to protein family HMM PF03591; branched-chain amino acid permease 171214 7685894 SPT_0193 Streptococcus pneumoniae Taiwan19F-14 branched-chain amino acid permease YP_002741697.1 170558 D 487213 CDS YP_002741698.1 225860189 7686816 171204..171527 1 NC_012469.1 identified by match to protein family HMM PF05437; branched-chain amino acid transport protein AzlD 171527 7686816 SPT_0194 Streptococcus pneumoniae Taiwan19F-14 branched-chain amino acid transport protein AzlD YP_002741698.1 171204 D 487213 CDS YP_002741699.1 225860190 7685834 171631..172461 1 NC_012469.1 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 172461 7685834 SPT_0195 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter substrate-binding protein YP_002741699.1 171631 D 487213 CDS YP_002741700.1 225860191 7686524 172615..173469 1 NC_012469.1 identified by match to protein family HMM PF03180; lipoprotein 173469 7686524 SPT_0196 Streptococcus pneumoniae Taiwan19F-14 lipoprotein YP_002741700.1 172615 D 487213 CDS YP_002741701.1 225860192 7685704 173569..174942 1 NC_012469.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase 174942 7685704 SPT_0197 Streptococcus pneumoniae Taiwan19F-14 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase YP_002741701.1 173569 D 487213 CDS YP_002741702.1 225860193 7687262 174935..175996 1 NC_012469.1 identified by match to protein family HMM PF00005; methionine import ATP-binding protein MetN 175996 7687262 SPT_0198 Streptococcus pneumoniae Taiwan19F-14 methionine import ATP-binding protein MetN YP_002741702.1 174935 D 487213 CDS YP_002741703.1 225860194 7685542 175998..176690 1 NC_012469.1 identified by match to protein family HMM PF00528; ABC transporter permease 176690 7685542 SPT_0199 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002741703.1 175998 D 487213 CDS YP_002741704.1 225860195 7686339 complement(176720..177289) 1 NC_012469.1 identified by match to protein family HMM TIGR02185; membrane-bound protein 177289 7686339 SPT_0200 Streptococcus pneumoniae Taiwan19F-14 membrane-bound protein YP_002741704.1 176720 R 487213 CDS YP_002741705.1 225860196 7685773 177424..178038 1 NC_012469.1 identified by match to protein family HMM PF04854; hypothetical protein 178038 7685773 SPT_0201 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741705.1 177424 D 487213 CDS YP_002741706.1 225860197 7686235 178088..179686 1 NC_012469.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580; sensor histidine kinase, putative 179686 7686235 SPT_0202 Streptococcus pneumoniae Taiwan19F-14 sensor histidine kinase, putative YP_002741706.1 178088 D 487213 CDS YP_002741707.1 225860198 7686675 179698..180984 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 180984 7686675 SPT_0203 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002741707.1 179698 D 487213 CDS YP_002741708.1 225860199 7686659 181036..181569 1 NC_012469.1 hypothetical protein 181569 7686659 SPT_0204 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741708.1 181036 D 487213 CDS YP_002741709.1 225860200 7687243 181647..182117 1 NC_012469.1 has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 182117 7687243 SPT_0205 Streptococcus pneumoniae Taiwan19F-14 flavoprotein NrdI YP_002741709.1 181647 D 487213 CDS YP_002741710.1 225860201 7686155 complement(182423..183769) 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 183769 7686155 SPT_0206 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002741710.1 182423 R 487213 CDS YP_002741711.1 225860202 7686399 complement(184118..185380) 1 NC_012469.1 mn2+ and fe2+ transporter of the nramp family 185380 7686399 SPT_0207 Streptococcus pneumoniae Taiwan19F-14 mn2+ and fe2+ transporter of the nramp family YP_002741711.1 184118 R 487213 CDS YP_002741712.1 225860203 7685446 complement(185690..186148) 1 NC_012469.1 hypothetical protein 186148 7685446 SPT_0208 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741712.1 185690 R 487213 CDS YP_002741713.1 225860204 7686757 complement(186145..186585) 1 NC_012469.1 identified by match to protein family HMM PF04397; response regulator of the LytR/AlgR family 186585 7686757 SPT_0209 Streptococcus pneumoniae Taiwan19F-14 response regulator of the LytR/AlgR family YP_002741713.1 186145 R 487213 CDS YP_002741714.1 225860205 7686148 complement(186673..186798) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 186798 7686148 SPT_0210 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741714.1 186673 R 487213 CDS YP_002741715.1 225860206 7687029 186941..188890 1 NC_012469.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 188890 mutL 7687029 mutL Streptococcus pneumoniae Taiwan19F-14 DNA mismatch repair protein YP_002741715.1 186941 D 487213 CDS YP_002741716.1 225860207 7686005 complement(189215..189682) 1 NC_012469.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 189682 ribH 7686005 ribH Streptococcus pneumoniae Taiwan19F-14 6,7-dimethyl-8-ribityllumazine synthase YP_002741716.1 189215 R 487213 CDS YP_002741717.1 225860208 7686924 complement(189683..190888) 1 NC_012469.1 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; riboflavin biosynthesis protein ribAB 190888 7686924 SPT_0213 Streptococcus pneumoniae Taiwan19F-14 riboflavin biosynthesis protein ribAB YP_002741717.1 189683 R 487213 CDS YP_002741718.1 225860209 7685646 complement(190908..191543) 1 NC_012469.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 191543 ribE 7685646 ribE Streptococcus pneumoniae Taiwan19F-14 riboflavin synthase subunit alpha YP_002741718.1 190908 R 487213 CDS YP_002741719.1 225860210 7687181 complement(191528..192628) 1 NC_012469.1 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 192628 ribD 7687181 ribD Streptococcus pneumoniae Taiwan19F-14 riboflavin biosynthesis protein RibD YP_002741719.1 191528 R 487213 CDS YP_002741720.1 225860211 7685296 193033..193626 1 NC_012469.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 193626 ruvA 7685296 ruvA Streptococcus pneumoniae Taiwan19F-14 Holliday junction DNA helicase RuvA YP_002741720.1 193033 D 487213 CDS YP_002741721.1 225860212 7685466 193636..194199 1 NC_012469.1 identified by match to protein family HMM PF03352; DNA-3-methyladenine glycosylase 1 194199 7685466 SPT_0217 Streptococcus pneumoniae Taiwan19F-14 DNA-3-methyladenine glycosylase 1 YP_002741721.1 193636 D 487213 CDS YP_002741722.1 225860213 7687030 194196..194873 1 NC_012469.1 identified by match to protein family HMM PF02517; caax amino protease family 194873 7687030 SPT_0218 Streptococcus pneumoniae Taiwan19F-14 caax amino protease family YP_002741722.1 194196 D 487213 CDS YP_002741723.1 225860214 7686014 complement(195010..196041) 1 NC_012469.1 identified by match to protein family HMM PF02016; MccC family protein 196041 7686014 SPT_0219 Streptococcus pneumoniae Taiwan19F-14 MccC family protein YP_002741723.1 195010 R 487213 CDS YP_002741724.1 225860215 7687215 complement(196296..196979) 1 NC_012469.1 identified by match to protein family HMM PF06570; hypothetical protein 196979 7687215 SPT_0220 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741724.1 196296 R 487213 CDS YP_002741725.1 225860216 7686682 complement(196991..197935) 1 NC_012469.1 identified by match to protein family HMM PF01544; magnesium and cobalt transporter 197935 7686682 SPT_0221 Streptococcus pneumoniae Taiwan19F-14 magnesium and cobalt transporter YP_002741725.1 196991 R 487213 CDS YP_002741726.1 225860217 7685946 complement(198096..199262) 1 NC_012469.1 identified by match to protein family HMM PF00589; prophage Sa05, site-specific recombinase, phage integrase family 199262 7685946 SPT_0222 Streptococcus pneumoniae Taiwan19F-14 prophage Sa05, site-specific recombinase, phage integrase family YP_002741726.1 198096 R 487213 CDS YP_002741727.1 225860218 7687016 complement(199347..200861) 1 NC_012469.1 identified by match to protein family HMM PF04326; divergent AAA domain family 200861 7687016 SPT_0223 Streptococcus pneumoniae Taiwan19F-14 divergent AAA domain family YP_002741727.1 199347 R 487213 CDS YP_002741728.1 225860219 7687271 complement(201022..201735) 1 NC_012469.1 identified by match to protein family HMM PF01381; putative DNA-binding phage protein 201735 7687271 SPT_0224 Streptococcus pneumoniae Taiwan19F-14 putative DNA-binding phage protein YP_002741728.1 201022 R 487213 CDS YP_002741729.1 225860220 7686974 201936..202118 1 NC_012469.1 putative DNA-binding phage protein 202118 7686974 SPT_0225 Streptococcus pneumoniae Taiwan19F-14 putative DNA-binding phage protein YP_002741729.1 201936 D 487213 CDS YP_002741730.1 225860221 7686363 202134..202760 1 NC_012469.1 hypothetical protein 202760 7686363 SPT_0226 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741730.1 202134 D 487213 CDS YP_002741731.1 225860222 7686779 203189..203584 1 NC_012469.1 hypothetical protein 203584 7686779 SPT_0227 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741731.1 203189 D 487213 CDS YP_002741732.1 225860223 7685289 203581..203781 1 NC_012469.1 hypothetical protein 203781 7685289 SPT_0228 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741732.1 203581 D 487213 CDS YP_002741733.1 225860224 7686782 203783..203998 1 NC_012469.1 hypothetical protein 203998 7686782 SPT_0229 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741733.1 203783 D 487213 CDS YP_002741734.1 225860225 7686223 203995..204336 1 NC_012469.1 phage protein 204336 7686223 SPT_0230 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741734.1 203995 D 487213 CDS YP_002741735.1 225860226 7686517 204329..204610 1 NC_012469.1 phage protein 204610 7686517 SPT_0231 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741735.1 204329 D 487213 CDS YP_002741736.1 225860227 7686451 204745..205611 1 NC_012469.1 identified by match to protein family HMM PF08708; phage protein 205611 7686451 SPT_0232 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741736.1 204745 D 487213 CDS YP_002741737.1 225860228 7685890 205664..207133 1 NC_012469.1 identified by match to protein family HMM PF08706; match to protein family HMM TIGR01613; prophage Sa05, DNA primase, P4 family 207133 7685890 SPT_0233 Streptococcus pneumoniae Taiwan19F-14 prophage Sa05, DNA primase, P4 family YP_002741737.1 205664 D 487213 CDS YP_002741738.1 225860229 7686546 207486..207653 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 207653 7686546 SPT_0234 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741738.1 207486 D 487213 CDS YP_002741739.1 225860230 7685858 207737..208267 1 NC_012469.1 phage protein 208267 7685858 SPT_0235 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741739.1 207737 D 487213 CDS YP_002741740.1 225860231 7686720 208716..208847 1 NC_012469.1 phage protein 208847 7686720 SPT_0236 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741740.1 208716 D 487213 CDS YP_002741741.1 225860232 7685527 210043..210462 1 NC_012469.1 identified by match to protein family HMM PF08281; phage protein 210462 7685527 SPT_0237 Streptococcus pneumoniae Taiwan19F-14 phage protein YP_002741741.1 210043 D 487213 CDS YP_002741742.1 225860233 7685760 210951..213782 1 NC_012469.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 213782 uvrA 7685760 uvrA Streptococcus pneumoniae Taiwan19F-14 excinuclease ABC subunit A YP_002741742.1 210951 D 487213 CDS YP_002741743.1 225860234 7686419 213775..214836 1 NC_012469.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase 214836 7686419 SPT_0239 Streptococcus pneumoniae Taiwan19F-14 Xaa-Pro dipeptidase YP_002741743.1 213775 D 487213 CDS YP_002741744.1 225860235 7685442 214968..215366 1 NC_012469.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 215366 spxA 7685442 spxA Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator Spx YP_002741744.1 214968 D 487213 CDS YP_002741745.1 225860236 7685288 215432..216001 1 NC_012469.1 lipoprotein, putative 216001 7685288 SPT_0241 Streptococcus pneumoniae Taiwan19F-14 lipoprotein, putative YP_002741745.1 215432 D 487213 CDS YP_002741746.1 225860237 7686618 216088..216354 1 NC_012469.1 identified by match to protein family HMM PF06135; hypothetical protein 216354 7686618 SPT_0242 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741746.1 216088 D 487213 CDS YP_002741747.1 225860238 7685839 216358..216777 1 NC_012469.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 216777 7685839 SPT_0243 Streptococcus pneumoniae Taiwan19F-14 Holliday junction resolvase-like protein YP_002741747.1 216358 D 487213 CDS YP_002741748.1 225860239 7687197 216793..217098 1 NC_012469.1 identified by match to protein family HMM PF06949; hypothetical protein 217098 7687197 SPT_0244 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741748.1 216793 D 487213 CDS YP_002741749.1 225860240 7685841 217406..218656 1 NC_012469.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; dihydrofolate:folylpolyglutamate synthetase 218656 7685841 SPT_0245 Streptococcus pneumoniae Taiwan19F-14 dihydrofolate:folylpolyglutamate synthetase YP_002741749.1 217406 D 487213 CDS YP_002741750.1 225860241 7686516 218740..219195 1 NC_012469.1 lipoprotein, putative 219195 7686516 SPT_0246 Streptococcus pneumoniae Taiwan19F-14 lipoprotein, putative YP_002741750.1 218740 D 487213 CDS YP_002741751.1 225860242 7685741 219341..220873 1 NC_012469.1 identified by match to protein family HMM PF00614; cardiolipin synthase 220873 7685741 SPT_0247 Streptococcus pneumoniae Taiwan19F-14 cardiolipin synthase YP_002741751.1 219341 D 487213 CDS YP_002741752.1 225860243 7687282 221131..222669 1 NC_012469.1 competence-induced protein Ccs4 222669 7687282 SPT_0248 Streptococcus pneumoniae Taiwan19F-14 competence-induced protein Ccs4 YP_002741752.1 221131 D 487213 CDS YP_002741753.1 225860244 7685533 222789..224996 1 NC_012469.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 224996 nrdD 7685533 nrdD Streptococcus pneumoniae Taiwan19F-14 anaerobic ribonucleoside triphosphate reductase YP_002741753.1 222789 D 487213 CDS YP_002741754.1 225860245 7687087 225028..225168 1 NC_012469.1 anaerobic ribonucleoside-triphosphate reductase 225168 7687087 SPT_0250 Streptococcus pneumoniae Taiwan19F-14 anaerobic ribonucleoside-triphosphate reductase YP_002741754.1 225028 D 487213 CDS YP_002741755.1 225860246 7686593 225180..225320 1 NC_012469.1 hypothetical protein 225320 7686593 SPT_0251 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741755.1 225180 D 487213 CDS YP_002741756.1 225860247 7685518 225364..225870 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 225870 7685518 SPT_0252 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002741756.1 225364 D 487213 CDS YP_002741757.1 225860248 7685331 225863..226453 1 NC_012469.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02491; anaerobic ribonucleoside-triphosphate reductase activating protein 226453 nrdG 7685331 nrdG Streptococcus pneumoniae Taiwan19F-14 anaerobic ribonucleoside-triphosphate reductase activating protein YP_002741757.1 225863 D 487213 CDS YP_002741758.1 225860249 7686105 226450..227067 1 NC_012469.1 identified by match to protein family HMM PF00485; phosphoribulokinase / Uridine kinase family 227067 7686105 SPT_0254 Streptococcus pneumoniae Taiwan19F-14 phosphoribulokinase / Uridine kinase family YP_002741758.1 226450 D 487213 CDS YP_002741759.1 225860250 7685805 227333..227641 1 NC_012469.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 227641 rpsJ 7685805 rpsJ Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S10 YP_002741759.1 227333 D 487213 CDS YP_002741760.1 225860251 7687330 227858..228484 1 NC_012469.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 228484 rplC 7687330 rplC Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L3 YP_002741760.1 227858 D 487213 CDS YP_002741761.1 225860252 7687312 228509..229132 1 NC_012469.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 229132 rplD 7687312 rplD Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L4 YP_002741761.1 228509 D 487213 CDS YP_002741762.1 225860253 7686477 229132..229428 1 NC_012469.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 229428 rplW 7686477 rplW Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L23 YP_002741762.1 229132 D 487213 CDS YP_002741763.1 225860254 7685222 229446..230279 1 NC_012469.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 230279 rplB 7685222 rplB Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L2 YP_002741763.1 229446 D 487213 CDS YP_002741764.1 225860255 7687195 230383..230664 1 NC_012469.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 230664 rpsS 7687195 rpsS Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S19 YP_002741764.1 230383 D 487213 CDS YP_002741765.1 225860256 7687163 230676..231020 1 NC_012469.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 231020 rplV 7687163 rplV Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L22 YP_002741765.1 230676 D 487213 CDS YP_002741766.1 225860257 7685281 231033..231686 1 NC_012469.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 231686 rpsC 7685281 rpsC Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S3 YP_002741766.1 231033 D 487213 CDS YP_002741767.1 225860258 7687018 231690..232103 1 NC_012469.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 232103 rplP 7687018 rplP Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L16 YP_002741767.1 231690 D 487213 CDS YP_002741768.1 225860259 7686688 232113..232319 1 NC_012469.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 232319 rpmC 7686688 rpmC Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L29 YP_002741768.1 232113 D 487213 CDS YP_002741769.1 225860260 7686000 232344..232604 1 NC_012469.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 232604 rpsQ 7686000 rpsQ Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S17 YP_002741769.1 232344 D 487213 CDS YP_002741770.1 225860261 7686998 232630..232998 1 NC_012469.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 232998 rplN 7686998 rplN Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L14 YP_002741770.1 232630 D 487213 CDS YP_002741771.1 225860262 7685682 233076..233381 1 NC_012469.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 233381 rplX 7685682 rplX Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L24 YP_002741771.1 233076 D 487213 CDS YP_002741772.1 225860263 7685869 233405..233947 1 NC_012469.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 233947 rplE 7685869 rplE Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L5 YP_002741772.1 233405 D 487213 CDS YP_002741773.1 225860264 7686227 233965..234234 1 NC_012469.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 234234 rpsN 7686227 rpsN Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S14 YP_002741773.1 233965 D 487213 CDS YP_002741774.1 225860265 7686289 234519..234917 1 NC_012469.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 234917 rpsH 7686289 rpsH Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S8 YP_002741774.1 234519 D 487213 CDS YP_002741775.1 225860266 7686364 235109..235645 1 NC_012469.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 235645 rplF 7686364 rplF Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L6 YP_002741775.1 235109 D 487213 CDS YP_002741776.1 225860267 7685719 235729..236085 1 NC_012469.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 236085 rplR 7685719 rplR Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L18 YP_002741776.1 235729 D 487213 CDS YP_002741777.1 225860268 7685750 236103..236597 1 NC_012469.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 236597 rpsE 7685750 rpsE Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S5 YP_002741777.1 236103 D 487213 CDS YP_002741778.1 225860269 7687264 236611..236793 1 NC_012469.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 236793 rpmD 7687264 rpmD Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L30 YP_002741778.1 236611 D 487213 CDS YP_002741779.1 225860270 7687381 236938..237378 1 NC_012469.1 late assembly protein; 50S ribosomal protein L15 237378 rplO 7687381 rplO Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L15 YP_002741779.1 236938 D 487213 CDS YP_002741780.1 225860271 7685910 237391..238701 1 NC_012469.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 238701 secY 7685910 secY Streptococcus pneumoniae Taiwan19F-14 preprotein translocase subunit SecY YP_002741780.1 237391 D 487213 CDS YP_002741781.1 225860272 7686320 238852..239490 1 NC_012469.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 239490 adk 7686320 adk Streptococcus pneumoniae Taiwan19F-14 adenylate kinase YP_002741781.1 238852 D 487213 CDS YP_002741782.1 225860273 7687211 239607..239825 1 NC_012469.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 239825 infA 7687211 infA Streptococcus pneumoniae Taiwan19F-14 translation initiation factor IF-1 YP_002741782.1 239607 D 487213 CDS YP_002741783.1 225860274 7686183 239850..239966 1 NC_012469.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 239966 rpmJ 7686183 rpmJ Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L36 YP_002741783.1 239850 D 487213 CDS YP_002741784.2 408843743 7687403 239984..>240298 1 NC_012469.1 truncated; an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00416; ribosomal protein S13p/S18e, unverified frameshift >240298 7687403 SPT_0280 Streptococcus pneumoniae Taiwan19F-14 ribosomal protein S13p/S18e, unverified frameshift YP_002741784.2 239984 D 487213 CDS YP_002741785.1 225860276 7686228 240368..240751 1 NC_012469.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 240751 rpsK 7686228 rpsK Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S11 YP_002741785.1 240368 D 487213 CDS YP_002741786.1 225860277 7686834 240794..241729 1 NC_012469.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 241729 rpoA 7686834 rpoA Streptococcus pneumoniae Taiwan19F-14 DNA-directed RNA polymerase subunit alpha YP_002741786.1 240794 D 487213 CDS YP_002741787.1 225860278 7687303 241741..242127 1 NC_012469.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 242127 rplQ 7687303 rplQ Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L17 YP_002741787.1 241741 D 487213 CDS YP_002741788.1 225860279 7686952 242392..242658 1 NC_012469.1 ACT domain-containing protein; hypothetical protein 242658 7686952 SPT_0284 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741788.1 242392 D 487213 CDS YP_002741789.1 225860280 7685219 242668..244005 1 NC_012469.1 identified by match to protein family HMM PF05167; hypothetical protein 244005 7685219 SPT_0285 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741789.1 242668 D 487213 CDS YP_002741790.1 225860281 7686037 244192..244941 1 NC_012469.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 244941 7686037 SPT_0286 Streptococcus pneumoniae Taiwan19F-14 phosphoglycerate mutase YP_002741790.1 244192 D 487213 CDS YP_002741791.1 225860282 7685935 complement(246679..247770) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; Fe(3+) ions import ATP-binding protein FbpC 247770 7685935 SPT_0289 Streptococcus pneumoniae Taiwan19F-14 Fe(3+) ions import ATP-binding protein FbpC YP_002741791.1 246679 R 487213 CDS YP_002741792.1 225860283 7686953 complement(249121..249318) 1 NC_012469.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 249318 7686953 SPT_0292 Streptococcus pneumoniae Taiwan19F-14 AraC family transcriptional regulator YP_002741792.1 249121 R 487213 CDS YP_002741793.1 225860284 7685480 complement(249393..250169) 1 NC_012469.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate-lyase 3 250169 7685480 SPT_0293 Streptococcus pneumoniae Taiwan19F-14 pyruvate formate-lyase 3 YP_002741793.1 249393 R 487213 CDS YP_002741794.1 225860285 7687220 250291..251037 1 NC_012469.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; putative HTH-type transcriptional regulator YciT 251037 7687220 SPT_0294 Streptococcus pneumoniae Taiwan19F-14 putative HTH-type transcriptional regulator YciT YP_002741794.1 250291 D 487213 CDS YP_002741795.1 225860286 7685925 251050..252030 1 NC_012469.1 identified by match to protein family HMM PF04198; transcriptional regulator 252030 7685925 SPT_0295 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator YP_002741795.1 251050 D 487213 CDS YP_002741796.1 225860287 7685486 252225..252545 1 NC_012469.1 identified by match to protein family HMM PF02255; phosphotransferase system sugar-specific eiia component 252545 7685486 SPT_0296 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific eiia component YP_002741796.1 252225 D 487213 CDS YP_002741797.1 225860288 7685797 252591..252899 1 NC_012469.1 identified by match to protein family HMM PF02302; PTS system, IIB component 252899 7685797 SPT_0297 Streptococcus pneumoniae Taiwan19F-14 PTS system, IIB component YP_002741797.1 252591 D 487213 CDS YP_002741798.1 225860289 7686737 252916..254214 1 NC_012469.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 254214 7686737 SPT_0298 Streptococcus pneumoniae Taiwan19F-14 lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) YP_002741798.1 252916 D 487213 CDS YP_002741799.1 225860290 7687317 254365..256803 1 NC_012469.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; pyruvate formate-lyase 256803 7687317 SPT_0299 Streptococcus pneumoniae Taiwan19F-14 pyruvate formate-lyase YP_002741799.1 254365 D 487213 CDS YP_002741800.1 225860291 7685370 256822..257490 1 NC_012469.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 257490 7685370 SPT_0300 Streptococcus pneumoniae Taiwan19F-14 fructose-6-phosphate aldolase YP_002741800.1 256822 D 487213 CDS YP_002741801.1 225860292 7686510 257508..258596 1 NC_012469.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 258596 gldA 7686510 gldA Streptococcus pneumoniae Taiwan19F-14 glycerol dehydrogenase YP_002741801.1 257508 D 487213 CDS YP_002741802.1 225860293 7685870 259051..261552 1 NC_012469.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 261552 leuS 7685870 leuS Streptococcus pneumoniae Taiwan19F-14 leucyl-tRNA synthetase YP_002741802.1 259051 D 487213 CDS YP_002741803.1 225860294 7685979 261691..262533 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 262533 7685979 SPT_0303 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741803.1 261691 D 487213 CDS YP_002741804.1 225860295 7686886 262589..263284 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 263284 7686886 SPT_0304 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002741804.1 262589 D 487213 CDS YP_002741805.1 225860296 7686502 263296..263712 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 263712 7686502 SPT_0305 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002741805.1 263296 D 487213 CDS YP_002741806.1 225860297 7686959 264753..265751 1 NC_012469.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 265751 ruvB 7686959 ruvB Streptococcus pneumoniae Taiwan19F-14 Holliday junction DNA helicase RuvB YP_002741806.1 264753 D 487213 CDS YP_002741807.1 225860298 7687166 266535..267293 1 NC_012469.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 267293 uppS 7687166 uppS Streptococcus pneumoniae Taiwan19F-14 UDP pyrophosphate synthase YP_002741807.1 266535 D 487213 CDS YP_002741808.1 225860299 7686390 267302..268105 1 NC_012469.1 identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 268105 cdsA 7686390 cdsA Streptococcus pneumoniae Taiwan19F-14 phosphatidate cytidylyltransferase YP_002741808.1 267302 D 487213 CDS YP_002741809.1 225860300 7686149 268127..269386 1 NC_012469.1 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; RIP metalloprotease RseP 269386 rseP 7686149 rseP Streptococcus pneumoniae Taiwan19F-14 RIP metalloprotease RseP YP_002741809.1 268127 D 487213 CDS YP_002741810.1 225860301 7686880 269399..271252 1 NC_012469.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 271252 proS 7686880 proS Streptococcus pneumoniae Taiwan19F-14 prolyl-tRNA synthetase YP_002741810.1 269399 D 487213 CDS YP_002741811.1 225860302 7686732 271352..272731 1 NC_012469.1 identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase 272731 7686732 SPT_0312 Streptococcus pneumoniae Taiwan19F-14 6-phospho-beta-glucosidase YP_002741811.1 271352 D 487213 CDS YP_002741812.1 225860303 7687324 272923..274731 1 NC_012469.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 274731 glmS 7687324 glmS Streptococcus pneumoniae Taiwan19F-14 glucosamine--fructose-6-phosphate aminotransferase YP_002741812.1 272923 D 487213 CDS YP_002741813.1 225860304 7685791 274850..275899 1 NC_012469.1 identified by match to protein family HMM PF00296; oxidoreductase 275899 7685791 SPT_0314 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase YP_002741813.1 274850 D 487213 CDS YP_002741814.1 225860305 7686814 complement(275999..279796) 1 NC_012469.1 identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102; pullulanase, extracellular 279796 7686814 SPT_0315 Streptococcus pneumoniae Taiwan19F-14 pullulanase, extracellular YP_002741814.1 275999 R 487213 CDS YP_002741815.1 225860306 7687185 280213..280626 1 NC_012469.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 280626 rpsL 7687185 rpsL Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S12 YP_002741815.1 280213 D 487213 CDS YP_002741816.1 225860307 7685233 280646..281116 1 NC_012469.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 281116 rpsG 7685233 rpsG Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S7 YP_002741816.1 280646 D 487213 CDS YP_002741817.1 225860308 7685367 281541..283622 1 NC_012469.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 283622 fusA 7685367 fusA Streptococcus pneumoniae Taiwan19F-14 elongation factor G YP_002741817.1 281541 D 487213 CDS YP_002741818.1 225860309 7687304 283726..288117 1 NC_012469.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 288117 polC 7687304 polC Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III PolC YP_002741818.1 283726 D 487213 CDS YP_002741819.1 225860310 7687133 288219..288482 1 NC_012469.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin, RelB/DinJ family 288482 7687133 SPT_0320 Streptococcus pneumoniae Taiwan19F-14 addiction module antitoxin, RelB/DinJ family YP_002741819.1 288219 D 487213 CDS YP_002741820.1 225860311 7685225 288475..288753 1 NC_012469.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; DNA damage inducible protein 288753 7685225 SPT_0321 Streptococcus pneumoniae Taiwan19F-14 DNA damage inducible protein YP_002741820.1 288475 D 487213 CDS YP_002741821.1 225860312 7685216 288774..288926 1 NC_012469.1 hypothetical protein 288926 7685216 SPT_0322 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741821.1 288774 D 487213 CDS YP_002741822.1 225860313 7687066 288948..290189 1 NC_012469.1 identified by match to protein family HMM PF02073; aminopeptidase PepS 290189 7687066 SPT_0323 Streptococcus pneumoniae Taiwan19F-14 aminopeptidase PepS YP_002741822.1 288948 D 487213 CDS YP_002741823.1 225860314 7685989 290199..290429 1 NC_012469.1 identified by match to protein family HMM PF04226; integral membrane protein 290429 7685989 SPT_0324 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002741823.1 290199 D 487213 CDS YP_002741824.1 225860315 7686679 290652..291374 1 NC_012469.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A, putative 291374 7686679 SPT_0325 Streptococcus pneumoniae Taiwan19F-14 ribosomal small subunit pseudouridine synthase A, putative YP_002741824.1 290652 D 487213 CDS YP_002741825.1 225860316 7685806 291591..292925 1 NC_012469.1 identified by match to protein family HMM PF03051; aminopeptidase C (Bleomycin hydrolase) 292925 7685806 SPT_0326 Streptococcus pneumoniae Taiwan19F-14 aminopeptidase C (Bleomycin hydrolase) YP_002741825.1 291591 D 487213 CDS YP_002741826.1 225860317 7685756 complement(292981..293892) 1 NC_012469.1 identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system, mannose/fructose/sorbose family, IID component 293892 7685756 SPT_0327 Streptococcus pneumoniae Taiwan19F-14 PTS system, mannose/fructose/sorbose family, IID component YP_002741826.1 292981 R 487213 CDS YP_002741827.1 225860318 7685202 complement(293916..294719) 1 NC_012469.1 identified by match to protein family HMM PF03609; PTS system sorbose-specific IIc component 294719 7685202 SPT_0328 Streptococcus pneumoniae Taiwan19F-14 PTS system sorbose-specific IIc component YP_002741827.1 293916 R 487213 CDS YP_002741828.1 225860319 7685368 complement(294747..295736) 1 NC_012469.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; mannose-specific phosphotransferase system component iiab 295736 7685368 SPT_0329 Streptococcus pneumoniae Taiwan19F-14 mannose-specific phosphotransferase system component iiab YP_002741828.1 294747 R 487213 CDS YP_002741829.1 225860320 7687071 complement(295969..296988) 1 NC_012469.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 296988 7687071 SPT_0330 Streptococcus pneumoniae Taiwan19F-14 alcohol dehydrogenase YP_002741829.1 295969 R 487213 CDS YP_002741830.1 225860321 7686849 complement(297097..297243) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 297243 7686849 SPT_0331 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741830.1 297097 R 487213 CDS YP_002741831.1 225860322 7686426 complement(297327..298139) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 298139 7686426 SPT_0332 Streptococcus pneumoniae Taiwan19F-14 Cof family protein YP_002741831.1 297327 R 487213 CDS YP_002741832.1 225860323 7686079 298275..299747 1 NC_012469.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inner membrane protein YicO 299747 7686079 SPT_0333 Streptococcus pneumoniae Taiwan19F-14 inner membrane protein YicO YP_002741832.1 298275 D 487213 CDS YP_002741833.1 225860324 7686254 299800..300507 1 NC_012469.1 identified by match to protein family HMM PF02517; caax amino protease family protein 300507 7686254 SPT_0334 Streptococcus pneumoniae Taiwan19F-14 caax amino protease family protein YP_002741833.1 299800 D 487213 CDS YP_002741834.1 225860325 7686560 300601..301578 1 NC_012469.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 301578 folP 7686560 folP Streptococcus pneumoniae Taiwan19F-14 dihydropteroate synthase YP_002741834.1 300601 D 487213 CDS YP_002741835.1 225860326 7686831 301580..302902 1 NC_012469.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; folylpolyglutamate synthase (folylpoly-gamma-glutamatesynthetase) (fpgs) (tetrahydrofolate synthase)(tetrahydrofolylpolyglutamate synthase) 302902 7686831 SPT_0336 Streptococcus pneumoniae Taiwan19F-14 folylpolyglutamate synthase (folylpoly-gamma-glutamatesynthetase) (fpgs) (tetrahydrofolate synthase)(tetrahydrofolylpolyglutamate synthase) YP_002741835.1 301580 D 487213 CDS YP_002741836.1 225860327 7686731 302883..303437 1 NC_012469.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 303437 folE 7686731 folE Streptococcus pneumoniae Taiwan19F-14 GTP cyclohydrolase I YP_002741836.1 302883 D 487213 CDS YP_002741837.1 225860328 7686359 303480..304292 1 NC_012469.1 identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498; bifunctional folate synthesis protein 304292 7686359 SPT_0338 Streptococcus pneumoniae Taiwan19F-14 bifunctional folate synthesis protein YP_002741837.1 303480 D 487213 CDS YP_002741838.1 225860329 7685420 complement(304337..304654) 1 NC_012469.1 hypothetical protein 304654 7685420 SPT_0339 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741838.1 304337 R 487213 CDS YP_002741839.1 225860330 7686367 305010..305456 1 NC_012469.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 305456 rplM 7686367 rplM Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L13 YP_002741839.1 305010 D 487213 CDS YP_002741840.1 225860331 7686605 305475..305867 1 NC_012469.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 305867 rpsI 7686605 rpsI Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S9 YP_002741840.1 305475 D 487213 CDS YP_002741841.1 225860332 7686716 complement(305976..307196) 1 NC_012469.1 identified by match to protein family HMM PF00589; integrase/recombinase, phage integrase family 307196 7686716 SPT_0342 Streptococcus pneumoniae Taiwan19F-14 integrase/recombinase, phage integrase family YP_002741841.1 305976 R 487213 CDS YP_002741842.1 225860333 7687100 complement(307238..307507) 1 NC_012469.1 identified by match to protein family HMM PF05930; match to protein family HMM TIGR01764; transcriptional regulator, AlpA family 307507 7687100 SPT_0343 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, AlpA family YP_002741842.1 307238 R 487213 CDS YP_002741843.1 225860334 7686883 complement(307515..308309) 1 NC_012469.1 Rep protein 308309 7686883 SPT_0344 Streptococcus pneumoniae Taiwan19F-14 Rep protein YP_002741843.1 307515 R 487213 CDS YP_002741844.1 225860335 7685494 complement(308481..309254) 1 NC_012469.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 309254 7685494 SPT_0345 Streptococcus pneumoniae Taiwan19F-14 Ser/Thr protein phosphatase family protein YP_002741844.1 308481 R 487213 CDS YP_002741845.1 225860336 7686940 complement(309329..310057) 1 NC_012469.1 identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein 310057 7686940 SPT_0346 Streptococcus pneumoniae Taiwan19F-14 Ser/Thr protein phosphatase family protein YP_002741845.1 309329 R 487213 CDS YP_002741846.1 225860337 7687144 complement(310484..311803) 1 NC_012469.1 identified by match to protein family HMM PF01580; putative otitis media-associated H10 311803 7687144 SPT_0347 Streptococcus pneumoniae Taiwan19F-14 putative otitis media-associated H10 YP_002741846.1 310484 R 487213 CDS YP_002741847.1 225860338 7686787 complement(311880..312350) 1 NC_012469.1 hypothetical protein 312350 7686787 SPT_0348 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741847.1 311880 R 487213 CDS YP_002741848.1 225860339 7685302 complement(312363..312950) 1 NC_012469.1 hypothetical protein 312950 7685302 SPT_0349 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741848.1 312363 R 487213 CDS YP_002741849.1 225860340 7686110 complement(313508..314119) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 314119 7686110 SPT_0350 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741849.1 313508 R 487213 CDS YP_002741850.1 225860341 7685706 complement(314166..314561) 1 NC_012469.1 hypothetical protein 314561 7685706 SPT_0351 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741850.1 314166 R 487213 CDS YP_002741851.1 225860342 7685515 315334..315516 1 NC_012469.1 Spn1, transposase Orf2 315516 7685515 SPT_0352 Streptococcus pneumoniae Taiwan19F-14 Spn1, transposase Orf2 YP_002741851.1 315334 D 487213 CDS YP_002741852.1 225860343 7685538 315672..316010 1 NC_012469.1 identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase 316010 7685538 SPT_0353 Streptococcus pneumoniae Taiwan19F-14 antibiotic biosynthesis monooxygenase YP_002741852.1 315672 D 487213 CDS YP_002741853.1 225860344 7686269 316200..317636 1 NC_012469.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 317636 celA 7686269 celA Streptococcus pneumoniae Taiwan19F-14 6-phospho-beta-glucosidase YP_002741853.1 316200 D 487213 CDS YP_002741854.1 225860345 7687191 317688..317927 1 NC_012469.1 identified by match to protein family HMM PF03083; glutathione synthetase 317927 7687191 SPT_0355 Streptococcus pneumoniae Taiwan19F-14 glutathione synthetase YP_002741854.1 317688 D 487213 CDS YP_002741855.1 225860346 7685822 318057..318371 1 NC_012469.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIB component 318371 celB 7685822 celB Streptococcus pneumoniae Taiwan19F-14 cellobiose phosphotransferase system IIB component YP_002741855.1 318057 D 487213 CDS YP_002741856.1 225860347 7687217 318495..320468 1 NC_012469.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; transcription antiterminator BglG family 320468 7687217 SPT_0357 Streptococcus pneumoniae Taiwan19F-14 transcription antiterminator BglG family YP_002741856.1 318495 D 487213 CDS YP_002741857.1 225860348 7685708 320478..320792 1 NC_012469.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIA component 320792 celC 7685708 celC Streptococcus pneumoniae Taiwan19F-14 cellobiose phosphotransferase system IIA component YP_002741857.1 320478 D 487213 CDS YP_002741858.1 225860349 7685505 320823..321329 1 NC_012469.1 hypothetical protein 321329 7685505 SPT_0359 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741858.1 320823 D 487213 CDS YP_002741859.1 225860350 7685409 321409..322755 1 NC_012469.1 required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIC component 322755 celD 7685409 celD Streptococcus pneumoniae Taiwan19F-14 cellobiose phosphotransferase system IIC component YP_002741859.1 321409 D 487213 CDS YP_002741860.1 225860351 7687365 323136..323312 1 NC_012469.1 hypothetical protein 323312 7687365 SPT_0361 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741860.1 323136 D 487213 CDS YP_002741861.1 225860352 7687050 323713..325926 1 NC_012469.1 identified by match to protein family HMM PF01055; glycosyl hydrolase, family 31 325926 7687050 SPT_0362 Streptococcus pneumoniae Taiwan19F-14 glycosyl hydrolase, family 31 YP_002741861.1 323713 D 487213 CDS YP_002741862.1 225860353 7687399 complement(326148..326624) 1 NC_012469.1 identified by match to protein family HMM PF00255; peroxiredoxin Hyr1 (hydrogen peroxide resistanceprotein 1) (oxidant receptor peroxidase 1) (glutathione peroxidase 3)(phospholipid hydroperoxide glutathione peroxidase 3) (phgpx3) 326624 7687399 SPT_0363 Streptococcus pneumoniae Taiwan19F-14 peroxiredoxin Hyr1 (hydrogen peroxide resistanceprotein 1) (oxidant receptor peroxidase 1) (glutathione peroxidase 3)(phospholipid hydroperoxide glutathione peroxidase 3) (phgpx3) YP_002741862.1 326148 R 487213 CDS YP_002741863.1 225860354 7686987 326847..330050 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167; hyaluronate lyase 330050 7686987 SPT_0364 Streptococcus pneumoniae Taiwan19F-14 hyaluronate lyase YP_002741863.1 326847 D 487213 CDS YP_002741864.1 225860355 7686608 complement(331151..331780) 1 NC_012469.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 331780 7686608 SPT_0366 Streptococcus pneumoniae Taiwan19F-14 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002741864.1 331151 R 487213 CDS YP_002741865.1 225860356 7685693 complement(331790..332791) 1 NC_012469.1 identified by match to protein family HMM PF00294; 2-keto-3-deoxygluconate kinase 332791 7685693 SPT_0367 Streptococcus pneumoniae Taiwan19F-14 2-keto-3-deoxygluconate kinase YP_002741865.1 331790 R 487213 CDS YP_002741866.1 225860357 7686455 complement(332822..333463) 1 NC_012469.1 identified by match to protein family HMM PF02502; hypothetical protein 333463 7686455 SPT_0368 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741866.1 332822 R 487213 CDS YP_002741867.1 225860358 7687327 complement(333482..334297) 1 NC_012469.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 334297 7687327 SPT_0369 Streptococcus pneumoniae Taiwan19F-14 gluconate 5-dehydrogenase YP_002741867.1 333482 R 487213 CDS YP_002741868.1 225860359 7686670 334569..335003 1 NC_012469.1 identified by match to protein family HMM PF03610; phosphotransferase system sugar-specific EII component 335003 7686670 SPT_0370 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002741868.1 334569 D 487213 CDS YP_002741869.1 225860360 7687266 335015..336205 1 NC_012469.1 identified by match to protein family HMM PF07470; unsaturated glucuronyl hydrolase (UGL) (Glycuronidase)(Unsaturated uronic acid hydrolase) (Glycosaminoglycan hydrolase) 336205 7687266 SPT_0371 Streptococcus pneumoniae Taiwan19F-14 unsaturated glucuronyl hydrolase (UGL) (Glycuronidase)(Unsaturated uronic acid hydrolase) (Glycosaminoglycan hydrolase) YP_002741869.1 335015 D 487213 CDS YP_002741870.1 225860361 7685437 336216..336707 1 NC_012469.1 identified by match to protein family HMM PF03830; N-acetylgalactosamine-specific phosphotransferase enzyme iib component2 (pts system n-acetylgalactosamine-specific eiibcomponent 2) (eiib-aga') 336707 7685437 SPT_0372 Streptococcus pneumoniae Taiwan19F-14 N-acetylgalactosamine-specific phosphotransferase enzyme iib component2 (pts system n-acetylgalactosamine-specific eiibcomponent 2) (eiib-aga') YP_002741870.1 336216 D 487213 CDS YP_002741871.1 225860362 7685338 336722..337501 1 NC_012469.1 identified by match to protein family HMM PF03609; phosphotransferase system sugar-specific EII component 337501 7685338 SPT_0373 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002741871.1 336722 D 487213 CDS YP_002741872.1 225860363 7685737 337488..338306 1 NC_012469.1 identified by match to protein family HMM PF03613; PTS system, IID component 338306 7685737 SPT_0374 Streptococcus pneumoniae Taiwan19F-14 PTS system, IID component YP_002741872.1 337488 D 487213 CDS YP_002741873.1 225860364 7686391 338306..338599 1 NC_012469.1 preprotein translocase, YajC subunit 338599 7686391 SPT_0375 Streptococcus pneumoniae Taiwan19F-14 preprotein translocase, YajC subunit YP_002741873.1 338306 D 487213 CDS YP_002741874.1 225860365 7685485 338621..340522 1 NC_012469.1 identified by match to protein family HMM PF07940; oligohyaluronate lyase 340522 7685485 SPT_0376 Streptococcus pneumoniae Taiwan19F-14 oligohyaluronate lyase YP_002741874.1 338621 D 487213 CDS YP_002741875.1 225860366 7686725 340582..341583 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar binding transcriptional regulator RegR 341583 7686725 SPT_0377 Streptococcus pneumoniae Taiwan19F-14 sugar binding transcriptional regulator RegR YP_002741875.1 340582 D 487213 CDS YP_002741876.1 225860367 7687235 341640..341762 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 341762 7687235 SPT_0378 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741876.1 341640 D 487213 CDS YP_002741877.1 225860368 7686470 complement(341854..342432) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 342432 7686470 SPT_0379 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741877.1 341854 R 487213 CDS YP_002741878.1 225860369 7686069 complement(342459..342590) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 342590 7686069 SPT_0380 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741878.1 342459 R 487213 CDS YP_002741879.1 225860370 7686690 complement(342658..342792) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 342792 7686690 SPT_0381 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741879.1 342658 R 487213 CDS YP_002741880.1 225860371 7687392 complement(342796..343338) 1 NC_012469.1 hypothetical protein 343338 7687392 SPT_0382 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741880.1 342796 R 487213 CDS YP_002741881.1 225860372 7686572 complement(343354..343548) 1 NC_012469.1 identified by match to protein family HMM PF01381; hypothetical protein 343548 7686572 SPT_0383 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741881.1 343354 R 487213 CDS YP_002741882.1 225860373 7685685 343714..344664 1 NC_012469.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 344664 mraW 7685685 mraW Streptococcus pneumoniae Taiwan19F-14 S-adenosyl-methyltransferase MraW YP_002741882.1 343714 D 487213 CDS YP_002741883.1 225860374 7685723 344677..344994 1 NC_012469.1 identified by match to protein family HMM TIGR02209; cell division protein FtsL 344994 ftsL 7685723 ftsL Streptococcus pneumoniae Taiwan19F-14 cell division protein FtsL YP_002741883.1 344677 D 487213 CDS YP_002741884.1 225860375 7687161 344998..347250 1 NC_012469.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; penicillin-binding protein 2x 347250 7687161 SPT_0386 Streptococcus pneumoniae Taiwan19F-14 penicillin-binding protein 2x YP_002741884.1 344998 D 487213 CDS YP_002741885.1 225860376 7685541 347252..348232 1 NC_012469.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 348232 mraY 7685541 mraY Streptococcus pneumoniae Taiwan19F-14 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002741885.1 347252 D 487213 CDS YP_002741886.1 225860377 7685957 348796..350901 1 NC_012469.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; ATP-dependent Clp protease ATP-binding subunit ClpL 350901 7685957 SPT_0388 Streptococcus pneumoniae Taiwan19F-14 ATP-dependent Clp protease ATP-binding subunit ClpL YP_002741886.1 348796 D 487213 CDS YP_002741887.1 225860378 7685557 complement(351196..351678) 1 NC_012469.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 351678 luxS 7685557 luxS Streptococcus pneumoniae Taiwan19F-14 S-ribosylhomocysteinase YP_002741887.1 351196 R 487213 CDS YP_002741888.1 225860379 7686207 complement(351773..353257) 1 NC_012469.1 identified by match to protein family HMM PF08903; hypothetical protein 353257 7686207 SPT_0390 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741888.1 351773 R 487213 CDS YP_002741889.1 225860380 7686271 353410..355017 1 NC_012469.1 identified by match to protein family HMM PF00128; trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase) 355017 7686271 SPT_0391 Streptococcus pneumoniae Taiwan19F-14 trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase) YP_002741889.1 353410 D 487213 CDS YP_002741890.1 225860381 7686312 356437..357882 1 NC_012469.1 identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350; integral membrane regulatory protein Wzg 357882 7686312 SPT_0392 Streptococcus pneumoniae Taiwan19F-14 integral membrane regulatory protein Wzg YP_002741890.1 356437 D 487213 CDS YP_002741891.1 225860382 7685512 357884..358615 1 NC_012469.1 identified by match to protein family HMM PF02811; tyrosine-protein phosphatase CpsB 358615 7685512 SPT_0393 Streptococcus pneumoniae Taiwan19F-14 tyrosine-protein phosphatase CpsB YP_002741891.1 357884 D 487213 CDS YP_002741892.1 225860383 7686211 358624..359316 1 NC_012469.1 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006; capsular polysaccharide biosynthesis protein CpsC 359316 7686211 SPT_0394 Streptococcus pneumoniae Taiwan19F-14 capsular polysaccharide biosynthesis protein CpsC YP_002741892.1 358624 D 487213 CDS YP_002741893.1 225860384 7686356 359326..360009 1 NC_012469.1 identified by match to protein family HMM TIGR01007; tyrosine-protein kinase CpsD 360009 7686356 SPT_0395 Streptococcus pneumoniae Taiwan19F-14 tyrosine-protein kinase CpsD YP_002741893.1 359326 D 487213 CDS YP_002741894.1 225860385 7687156 360394..361392 1 NC_012469.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03025; galactosyl transferase CpsE 361392 7687156 SPT_0396 Streptococcus pneumoniae Taiwan19F-14 galactosyl transferase CpsE YP_002741894.1 360394 D 487213 CDS YP_002741895.1 225860386 7686890 361396..362139 1 NC_012469.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosamine transferase 362139 7686890 SPT_0397 Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetyl-D-mannosamine transferase YP_002741895.1 361396 D 487213 CDS YP_002741896.1 225860387 7685904 362136..362960 1 NC_012469.1 identified by match to protein family HMM PF04991; 31.6 kDa cps19fG gene product 362960 7685904 SPT_0398 Streptococcus pneumoniae Taiwan19F-14 31.6 kDa cps19fG gene product YP_002741896.1 362136 D 487213 CDS YP_002741897.1 225860388 7686937 362962..363840 1 NC_012469.1 identified by match to protein family HMM PF00535; putative rhamnosyl transferase 363840 7686937 SPT_0399 Streptococcus pneumoniae Taiwan19F-14 putative rhamnosyl transferase YP_002741897.1 362962 D 487213 CDS YP_002741898.1 225860389 7685947 363841..365178 1 NC_012469.1 polysaccharide polymerase Cps19aI 365178 7685947 SPT_0400 Streptococcus pneumoniae Taiwan19F-14 polysaccharide polymerase Cps19aI YP_002741898.1 363841 D 487213 CDS YP_002741899.1 225860390 7685648 365201..366622 1 NC_012469.1 flippase Wzx 366622 7685648 SPT_0401 Streptococcus pneumoniae Taiwan19F-14 flippase Wzx YP_002741899.1 365201 D 487213 CDS YP_002741900.1 225860391 7686401 366686..367774 1 NC_012469.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 367774 7686401 SPT_0402 Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylglucosamine 2-epimerase YP_002741900.1 366686 D 487213 CDS YP_002741901.1 225860392 7686865 367813..368682 1 NC_012469.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 368682 rfbA 7686865 rfbA Streptococcus pneumoniae Taiwan19F-14 glucose-1-phosphate thymidylyltransferase YP_002741901.1 367813 D 487213 CDS YP_002741902.1 225860393 7687296 368683..369279 1 NC_012469.1 identified by match to protein family HMM PF00908; dTDP-4-dehydrorhamnose 3,5-epimerase 369279 7687296 SPT_0404 Streptococcus pneumoniae Taiwan19F-14 dTDP-4-dehydrorhamnose 3,5-epimerase YP_002741902.1 368683 D 487213 CDS YP_002741903.1 225860394 7686116 369289..370338 1 NC_012469.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 370338 rfbB 7686116 rfbB Streptococcus pneumoniae Taiwan19F-14 dTDP-glucose 4,6-dehydratase YP_002741903.1 369289 D 487213 CDS YP_002741904.1 225860395 7686156 370404..371255 1 NC_012469.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase 371255 rfbD 7686156 rfbD Streptococcus pneumoniae Taiwan19F-14 dTDP-4-dehydrorhamnose reductase YP_002741904.1 370404 D 487213 CDS YP_002741905.1 225860396 7686070 complement(372400..372522) 1 NC_012469.1 hypothetical protein 372522 7686070 SPT_0408 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741905.1 372400 R 487213 CDS YP_002741906.1 225860397 7686066 372724..374706 1 NC_012469.1 identified by match to protein family HMM PF00496; oligopeptide binding protein 374706 7686066 SPT_0410 Streptococcus pneumoniae Taiwan19F-14 oligopeptide binding protein YP_002741906.1 372724 D 487213 CDS YP_002741907.1 225860398 7685213 375007..380310 1 NC_012469.1 identified by match to protein family HMM PF00754; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; endo-alpha-N-acetylgalactosaminidase 380310 7685213 SPT_0411 Streptococcus pneumoniae Taiwan19F-14 endo-alpha-N-acetylgalactosaminidase YP_002741907.1 375007 D 487213 CDS YP_002741908.1 225860399 7686147 complement(380476..382635) 1 NC_012469.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1a 382635 7686147 SPT_0412 Streptococcus pneumoniae Taiwan19F-14 penicillin-binding protein 1a YP_002741908.1 380476 R 487213 CDS YP_002741909.1 225860400 7686341 complement(382632..383228) 1 NC_012469.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 383228 recU 7686341 recU Streptococcus pneumoniae Taiwan19F-14 Holliday junction-specific endonuclease YP_002741909.1 382632 R 487213 CDS YP_002741910.1 225860401 7685999 383295..383822 1 NC_012469.1 identified by match to protein family HMM PF06908; hypothetical protein 383822 7685999 SPT_0414 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741910.1 383295 D 487213 CDS YP_002741911.1 225860402 7687034 383892..384233 1 NC_012469.1 identified by match to protein family HMM PF05103; cell division initiation protein 384233 7687034 SPT_0415 Streptococcus pneumoniae Taiwan19F-14 cell division initiation protein YP_002741911.1 383892 D 487213 CDS YP_002741912.1 225860403 7685560 384719..385876 1 NC_012469.1 identified by match to protein family HMM PF01170; methyltransferase 385876 7685560 SPT_0416 Streptococcus pneumoniae Taiwan19F-14 methyltransferase YP_002741912.1 384719 D 487213 CDS YP_002741913.1 225860404 7687255 385889..387283 1 NC_012469.1 hypothetical protein 387283 7687255 SPT_0417 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741913.1 385889 D 487213 CDS YP_002741914.1 225860405 7685671 387359..388783 1 NC_012469.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 388783 gnd 7685671 gnd Streptococcus pneumoniae Taiwan19F-14 6-phosphogluconate dehydrogenase YP_002741914.1 387359 D 487213 CDS YP_002741915.1 225860406 7687055 388795..389484 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 389484 7687055 SPT_0419 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002741915.1 388795 D 487213 CDS YP_002741916.1 225860407 7685317 389582..390544 1 NC_012469.1 identified by match to protein family HMM PF01473; choline-binding protein F 390544 7685317 SPT_0420 Streptococcus pneumoniae Taiwan19F-14 choline-binding protein F YP_002741916.1 389582 D 487213 CDS YP_002741917.1 225860408 7686568 390563..391561 1 NC_012469.1 identified by match to protein family HMM PF01473; choline binding protein J 391561 7686568 SPT_0421 Streptococcus pneumoniae Taiwan19F-14 choline binding protein J YP_002741917.1 390563 D 487213 CDS YP_002741918.1 225860409 7685425 complement(391679..392911) 1 NC_012469.1 identified by match to protein family HMM PF07690; transporter, major facilitator family protein 392911 7685425 SPT_0422 Streptococcus pneumoniae Taiwan19F-14 transporter, major facilitator family protein YP_002741918.1 391679 R 487213 CDS YP_002741919.1 225860410 7685528 complement(392954..393373) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 393373 7685528 SPT_0423 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741919.1 392954 R 487213 CDS YP_002741920.1 225860411 7686760 complement(393441..393779) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 393779 7686760 SPT_0424 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741920.1 393441 R 487213 CDS YP_002741921.1 225860412 7685896 394649..394771 1 NC_012469.1 identified by match to protein family HMM PF01473; choline-binding protein F 394771 7685896 SPT_0425 Streptococcus pneumoniae Taiwan19F-14 choline-binding protein F YP_002741921.1 394649 D 487213 CDS YP_002741922.1 225860413 7686527 394893..395771 1 NC_012469.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549; mevalonate kinase 395771 mvk 7686527 mvk Streptococcus pneumoniae Taiwan19F-14 mevalonate kinase YP_002741922.1 394893 D 487213 CDS YP_002741923.1 225860414 7685832 395753..396706 1 NC_012469.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240; diphosphomevalonate decarboxylase 396706 mvaD 7685832 mvaD Streptococcus pneumoniae Taiwan19F-14 diphosphomevalonate decarboxylase YP_002741923.1 395753 D 487213 CDS YP_002741924.1 225860415 7686057 396693..397700 1 NC_012469.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220; phosphomevalonate kinase 397700 7686057 SPT_0428 Streptococcus pneumoniae Taiwan19F-14 phosphomevalonate kinase YP_002741924.1 396693 D 487213 CDS YP_002741925.1 225860416 7686941 397684..398694 1 NC_012469.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 398694 fni 7686941 fni Streptococcus pneumoniae Taiwan19F-14 isopentenyl pyrophosphate isomerase YP_002741925.1 397684 D 487213 CDS YP_002741926.1 225860417 7685915 398772..399470 1 NC_012469.1 hypothetical protein 399470 7685915 SPT_0430 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741926.1 398772 D 487213 CDS YP_002741927.1 225860418 7686013 399467..400462 1 NC_012469.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 400462 7686013 SPT_0431 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002741927.1 399467 D 487213 CDS YP_002741928.1 225860419 7686672 400476..401108 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281; response regulator 401108 7686672 SPT_0432 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002741928.1 400476 D 487213 CDS YP_002741929.1 225860420 7686153 401109..401255 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 401255 7686153 SPT_0433 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741929.1 401109 D 487213 CDS YP_002741930.1 225860421 7685667 401702..401878 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 401878 7685667 SPT_0435 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741930.1 401702 D 487213 CDS YP_002741931.1 225860422 7686607 402028..402942 1 NC_012469.1 identified by match to protein family HMM PF00089; choline binding protein G 402942 7686607 SPT_0436 Streptococcus pneumoniae Taiwan19F-14 choline binding protein G YP_002741931.1 402028 D 487213 CDS YP_002741932.1 225860423 7686049 403235..403600 1 NC_012469.1 integrase 403600 7686049 SPT_0437 Streptococcus pneumoniae Taiwan19F-14 integrase YP_002741932.1 403235 D 487213 CDS YP_002741933.1 225860424 7686809 403794..405077 1 NC_012469.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 405077 tig 7686809 tig Streptococcus pneumoniae Taiwan19F-14 trigger factor YP_002741933.1 403794 D 487213 CDS YP_002741934.1 225860425 7687061 complement(405125..407491) 1 NC_012469.1 identified by match to protein family HMM TIGR01448; helicase, RecD/TraA family 407491 7687061 SPT_0439 Streptococcus pneumoniae Taiwan19F-14 helicase, RecD/TraA family YP_002741934.1 405125 R 487213 CDS YP_002741935.1 225860426 7687128 complement(407619..408233) 1 NC_012469.1 identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I 408233 lepB1 7687128 lepB1 Streptococcus pneumoniae Taiwan19F-14 signal peptidase I YP_002741935.1 407619 R 487213 CDS YP_002741936.1 225860427 7685523 complement(408237..409118) 1 NC_012469.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 409118 rnhC 7685523 rnhC Streptococcus pneumoniae Taiwan19F-14 ribonuclease HIII YP_002741936.1 408237 R 487213 CDS YP_002741937.1 225860428 7685711 409283..409507 1 NC_012469.1 hypothetical protein 409507 7685711 SPT_0442 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741937.1 409283 D 487213 CDS YP_002741938.1 225860429 7685888 409504..410052 1 NC_012469.1 identified by match to protein family HMM PF02674; CvpA family protein 410052 cvpA 7685888 cvpA Streptococcus pneumoniae Taiwan19F-14 CvpA family protein YP_002741938.1 409504 D 487213 CDS YP_002741939.1 225860430 7686544 410156..412492 1 NC_012469.1 identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069; MutS2 family protein 412492 7686544 SPT_0444 Streptococcus pneumoniae Taiwan19F-14 MutS2 family protein YP_002741939.1 410156 D 487213 CDS YP_002741940.1 225860431 7685410 412835..414151 1 NC_012469.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 414151 7685410 SPT_0445 Streptococcus pneumoniae Taiwan19F-14 sodium:alanine symporter family protein YP_002741940.1 412835 D 487213 CDS YP_002741941.1 225860432 7685953 414369..414917 1 NC_012469.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; macrophage infectivity potentiator protein 414917 7685953 SPT_0446 Streptococcus pneumoniae Taiwan19F-14 macrophage infectivity potentiator protein YP_002741941.1 414369 D 487213 CDS YP_002741942.1 225860433 7686981 415027..415926 1 NC_012469.1 identified by match to protein family HMM PF03595; exfoliative toxin A 415926 7686981 SPT_0447 Streptococcus pneumoniae Taiwan19F-14 exfoliative toxin A YP_002741942.1 415027 D 487213 CDS YP_002741943.1 225860434 7687154 complement(415951..417225) 1 NC_012469.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 417225 serS 7687154 serS Streptococcus pneumoniae Taiwan19F-14 seryl-tRNA synthetase YP_002741943.1 415951 R 487213 CDS YP_002741944.1 225860435 7685837 complement(417439..417810) 1 NC_012469.1 identified by match to protein family HMM PF06115; ManO 417810 7685837 SPT_0449 Streptococcus pneumoniae Taiwan19F-14 ManO YP_002741944.1 417439 R 487213 CDS YP_002741945.1 225860436 7686871 complement(417813..419177) 1 NC_012469.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 419177 7686871 SPT_0450 Streptococcus pneumoniae Taiwan19F-14 aspartate kinase YP_002741945.1 417813 R 487213 CDS YP_002741946.1 225860437 7686840 complement(419355..419510) 1 NC_012469.1 hypothetical protein 419510 7686840 SPT_0451 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741946.1 419355 R 487213 CDS YP_002741947.1 225860438 7687160 419502..420287 1 NC_012469.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 420287 7687160 SPT_0452 Streptococcus pneumoniae Taiwan19F-14 enoyl-CoA hydratase YP_002741947.1 419502 D 487213 CDS YP_002741948.1 225860439 7685346 420381..420815 1 NC_012469.1 identified by match to protein family HMM PF01047; match to protein family HMM PF03965; transcriptional regulator 420815 7685346 SPT_0453 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator YP_002741948.1 420381 D 487213 CDS YP_002741949.1 225860440 7686936 420815..421789 1 NC_012469.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 421789 7686936 SPT_0454 Streptococcus pneumoniae Taiwan19F-14 3-oxoacyl-(acyl carrier protein) synthase III YP_002741949.1 420815 D 487213 CDS YP_002741950.1 225860441 7685443 421849..422073 1 NC_012469.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 422073 acpP 7685443 acpP Streptococcus pneumoniae Taiwan19F-14 acyl carrier protein YP_002741950.1 421849 D 487213 CDS YP_002741951.1 225860442 7686012 422192..423166 1 NC_012469.1 identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151; enoyl-ACP reductase II 423166 7686012 SPT_0456 Streptococcus pneumoniae Taiwan19F-14 enoyl-ACP reductase II YP_002741951.1 422192 D 487213 CDS YP_002741952.1 225860443 7686236 423159..424079 1 NC_012469.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 424079 fabD 7686236 fabD Streptococcus pneumoniae Taiwan19F-14 malonyl CoA-acyl carrier protein transacylase YP_002741952.1 423159 D 487213 CDS YP_002741953.1 225860444 7686124 424113..424844 1 NC_012469.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 424844 fabG 7686124 fabG Streptococcus pneumoniae Taiwan19F-14 3-ketoacyl-ACP reductase YP_002741953.1 424113 D 487213 CDS YP_002741954.1 225860445 7686131 424866..426101 1 NC_012469.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 426101 fabF 7686131 fabF Streptococcus pneumoniae Taiwan19F-14 3-oxoacyl-(acyl carrier protein) synthase II YP_002741954.1 424866 D 487213 CDS YP_002741955.1 225860446 7687024 426104..426589 1 NC_012469.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 426589 accB 7687024 accB Streptococcus pneumoniae Taiwan19F-14 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002741955.1 426104 D 487213 CDS YP_002741956.1 225860447 7685782 426586..427008 1 NC_012469.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 427008 fabZ 7685782 fabZ Streptococcus pneumoniae Taiwan19F-14 (3R)-hydroxymyristoyl-ACP dehydratase YP_002741956.1 426586 D 487213 CDS YP_002741957.1 225860448 7687212 427020..428387 1 NC_012469.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 428387 accC 7687212 accC Streptococcus pneumoniae Taiwan19F-14 acetyl-CoA carboxylase biotin carboxylase subunit YP_002741957.1 427020 D 487213 CDS YP_002741958.1 225860449 7686590 428424..429290 1 NC_012469.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 429290 accD 7686590 accD Streptococcus pneumoniae Taiwan19F-14 acetyl-CoA carboxylase subunit beta YP_002741958.1 428424 D 487213 CDS YP_002741959.1 225860450 7685666 429287..430054 1 NC_012469.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 430054 accA 7685666 accA Streptococcus pneumoniae Taiwan19F-14 acetyl-CoA carboxylase subunit alpha YP_002741959.1 429287 D 487213 CDS YP_002741960.1 225860451 7685686 430317..430502 1 NC_012469.1 hypothetical protein 430502 7685686 SPT_0465 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741960.1 430317 D 487213 CDS YP_002741961.1 225860452 7687040 430559..430693 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 430693 7687040 SPT_0466 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741961.1 430559 D 487213 CDS YP_002741962.1 225860453 7687079 430843..430971 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 430971 7687079 SPT_0467 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741962.1 430843 D 487213 CDS YP_002741963.1 225860454 7685497 complement(431270..431692) 1 NC_012469.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 431692 nusB 7685497 nusB Streptococcus pneumoniae Taiwan19F-14 transcription antitermination protein NusB YP_002741963.1 431270 R 487213 CDS YP_002741964.1 225860455 7686815 complement(431685..432074) 1 NC_012469.1 identified by match to protein family HMM PF03780; general stress protein, Gls24 family 432074 7686815 SPT_0469 Streptococcus pneumoniae Taiwan19F-14 general stress protein, Gls24 family YP_002741964.1 431685 R 487213 CDS YP_002741965.1 225860456 7686480 complement(432096..432656) 1 NC_012469.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 432656 efp 7686480 efp Streptococcus pneumoniae Taiwan19F-14 elongation factor P YP_002741965.1 432096 R 487213 CDS YP_002741966.1 225860457 7686554 432824..433009 1 NC_012469.1 chlorohydrolase 433009 7686554 SPT_0471 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002741966.1 432824 D 487213 CDS YP_002741967.1 225860458 7685721 complement(433034..434077) 1 NC_012469.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-iditol 2-dehydrogenase 434077 7685721 SPT_0472 Streptococcus pneumoniae Taiwan19F-14 L-iditol 2-dehydrogenase YP_002741967.1 433034 R 487213 CDS YP_002741968.1 225860459 7686771 complement(434201..435643) 1 NC_012469.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 435643 gatB 7686771 gatB Streptococcus pneumoniae Taiwan19F-14 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_002741968.1 434201 R 487213 CDS YP_002741969.1 225860460 7686830 complement(435643..437109) 1 NC_012469.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 437109 gatA 7686830 gatA Streptococcus pneumoniae Taiwan19F-14 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_002741969.1 435643 R 487213 CDS YP_002741970.1 225860461 7685380 complement(437109..437411) 1 NC_012469.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 437411 gatC 7685380 gatC Streptococcus pneumoniae Taiwan19F-14 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_002741970.1 437109 R 487213 CDS YP_002741971.1 225860462 7685897 437624..439168 1 NC_012469.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 439168 prfC 7685897 prfC Streptococcus pneumoniae Taiwan19F-14 peptide chain release factor 3 YP_002741971.1 437624 D 487213 CDS YP_002741972.1 225860463 7686071 440196..440384 1 NC_012469.1 required for 70S ribosome assembly; 50S ribosomal protein L28 440384 rpmB 7686071 rpmB Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L28 YP_002741972.1 440196 D 487213 CDS YP_002741973.1 225860464 7685328 440541..440906 1 NC_012469.1 identified by match to protein family HMM PF03780; alkaline shock protein 440906 7685328 SPT_0479 Streptococcus pneumoniae Taiwan19F-14 alkaline shock protein YP_002741973.1 440541 D 487213 CDS YP_002741974.1 225860465 7685488 440909..442576 1 NC_012469.1 identified by match to protein family HMM PF02734; dihydroxyacetone kinase family protein 442576 7685488 SPT_0480 Streptococcus pneumoniae Taiwan19F-14 dihydroxyacetone kinase family protein YP_002741974.1 440909 D 487213 CDS YP_002741975.1 225860466 7686182 442776..444476 1 NC_012469.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 444476 ilvB 7686182 ilvB Streptococcus pneumoniae Taiwan19F-14 acetolactate synthase catalytic subunit YP_002741975.1 442776 D 487213 CDS YP_002741976.1 225860467 7685508 444469..444945 1 NC_012469.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 444945 ilvH 7685508 ilvH Streptococcus pneumoniae Taiwan19F-14 acetolactate synthase 3 regulatory subunit YP_002741976.1 444469 D 487213 CDS YP_002741977.1 225860468 7685793 445011..446033 1 NC_012469.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 446033 ilvC 7685793 ilvC Streptococcus pneumoniae Taiwan19F-14 ketol-acid reductoisomerase YP_002741977.1 445011 D 487213 CDS YP_002741978.1 225860469 7686643 446140..446376 1 NC_012469.1 hypothetical protein 446376 7686643 SPT_0484 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741978.1 446140 D 487213 CDS YP_002741979.1 225860470 7686642 446614..446970 1 NC_012469.1 hypothetical protein 446970 7686642 SPT_0485 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741979.1 446614 D 487213 CDS YP_002741980.1 225860471 7686058 447020..448270 1 NC_012469.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 448270 ilvA 7686058 ilvA Streptococcus pneumoniae Taiwan19F-14 threonine dehydratase YP_002741980.1 447020 D 487213 CDS YP_002741981.1 225860472 7685429 448412..448600 1 NC_012469.1 hypothetical protein 448600 7685429 SPT_0487 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741981.1 448412 D 487213 CDS YP_002741982.1 225860473 7687388 449141..449356 1 NC_012469.1 hypothetical protein 449356 7687388 SPT_0488 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741982.1 449141 D 487213 CDS YP_002741983.1 225860474 7686424 complement(449465..450205) 1 NC_012469.1 identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter, ATP-binding protein 450205 gltL 7686424 gltL Streptococcus pneumoniae Taiwan19F-14 glutamate/aspartate ABC transporter, ATP-binding protein YP_002741983.1 449465 R 487213 CDS YP_002741984.1 225860475 7687037 complement(450205..451770) 1 NC_012469.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein 451770 7687037 SPT_0490 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter permease/substrate-binding protein YP_002741984.1 450205 R 487213 CDS YP_002741985.1 225860476 7687183 451908..453797 1 NC_012469.1 hypothetical protein 453797 7687183 SPT_0492 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741985.1 451908 D 487213 CDS YP_002741986.1 225860477 7686984 complement(453794..453964) 1 NC_012469.1 hypothetical protein 453964 7686984 SPT_0491 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741986.1 453794 R 487213 CDS YP_002741987.1 225860478 7685996 complement(454844..454966) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 454966 7685996 SPT_0494 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741987.1 454844 R 487213 CDS YP_002741988.1 225860479 7687027 455222..456067 1 NC_012469.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 456067 7687027 SPT_0495 Streptococcus pneumoniae Taiwan19F-14 UDP pyrophosphate phosphatase YP_002741988.1 455222 D 487213 CDS YP_002741989.1 225860480 7686145 456060..456188 1 NC_012469.1 hypothetical protein 456188 7686145 SPT_0496 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741989.1 456060 D 487213 CDS YP_002741990.1 225860481 7686242 complement(456214..457275) 1 NC_012469.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 457275 7686242 SPT_0497 Streptococcus pneumoniae Taiwan19F-14 DNA polymerase IV YP_002741990.1 456214 R 487213 CDS YP_002741991.1 225860482 7686660 457623..459947 1 NC_012469.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 459947 pflB 7686660 pflB Streptococcus pneumoniae Taiwan19F-14 formate acetyltransferase YP_002741991.1 457623 D 487213 CDS YP_002741992.1 225860483 7685293 complement(460005..461267) 1 NC_012469.1 identified by match to protein family HMM PF01610; transposase 461267 7685293 SPT_0499 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002741992.1 460005 R 487213 CDS YP_002741993.1 225860484 7687341 complement(461532..463061) 1 NC_012469.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08280; transcriptional regulator, putative 463061 7687341 SPT_0500 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, putative YP_002741993.1 461532 R 487213 CDS YP_002741994.1 225860485 7686189 463577..466237 1 NC_012469.1 identified by match to protein family HMM PF00092; match to protein family HMM PF05738; cell wall surface anchor family protein 466237 7686189 SPT_0501 Streptococcus pneumoniae Taiwan19F-14 cell wall surface anchor family protein YP_002741994.1 463577 D 487213 CDS YP_002741995.1 225860486 7685492 466460..468457 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167; cell wall surface anchor family protein 468457 7685492 SPT_0503 Streptococcus pneumoniae Taiwan19F-14 cell wall surface anchor family protein YP_002741995.1 466460 D 487213 CDS YP_002741996.1 225860487 7687221 complement(468423..468725) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 468725 7687221 SPT_0502 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002741996.1 468423 R 487213 CDS YP_002741997.1 225860488 7686321 468774..469685 1 NC_012469.1 identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167; cell wall surface anchor family protein 469685 7686321 SPT_0504 Streptococcus pneumoniae Taiwan19F-14 cell wall surface anchor family protein YP_002741997.1 468774 D 487213 CDS YP_002741998.1 225860489 7685998 470024..470920 1 NC_012469.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase family protein 470920 7685998 SPT_0505 Streptococcus pneumoniae Taiwan19F-14 sortase family protein YP_002741998.1 470024 D 487213 CDS YP_002741999.1 225860490 7686624 470989..471807 1 NC_012469.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase family protein 471807 7686624 SPT_0506 Streptococcus pneumoniae Taiwan19F-14 sortase family protein YP_002741999.1 470989 D 487213 CDS YP_002742000.1 225860491 7686119 471836..472645 1 NC_012469.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase, putative 472645 7686119 SPT_0507 Streptococcus pneumoniae Taiwan19F-14 sortase, putative YP_002742000.1 471836 D 487213 CDS YP_002742001.1 225860492 7685484 complement(474158..474307) 1 NC_012469.1 hypothetical protein 474307 7685484 SPT_0511 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742001.1 474158 R 487213 CDS YP_002742002.1 225860493 7687335 complement(474300..474584) 1 NC_012469.1 hypothetical protein 474584 7687335 SPT_0512 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742002.1 474300 R 487213 CDS YP_002742003.1 225860494 7685308 complement(475181..475351) 1 NC_012469.1 hypothetical protein 475351 7685308 SPT_0513 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742003.1 475181 R 487213 CDS YP_002742004.1 225860495 7686740 complement(476005..477228) 1 NC_012469.1 identified by match to protein family HMM PF00480; ROK family protein 477228 7686740 SPT_0514 Streptococcus pneumoniae Taiwan19F-14 ROK family protein YP_002742004.1 476005 R 487213 CDS YP_002742005.1 225860496 7685621 477395..478717 1 NC_012469.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 478717 7685621 SPT_0515 Streptococcus pneumoniae Taiwan19F-14 lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) YP_002742005.1 477395 D 487213 CDS YP_002742006.1 225860497 7685381 478719..480605 1 NC_012469.1 hypothetical protein 480605 7685381 SPT_0516 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742006.1 478719 D 487213 CDS YP_002742007.1 225860498 7685224 480773..481117 1 NC_012469.1 identified by match to protein family HMM PF02255; lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) 481117 7685224 SPT_0517 Streptococcus pneumoniae Taiwan19F-14 lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) YP_002742007.1 480773 D 487213 CDS YP_002742008.1 225860499 7685343 481127..482539 1 NC_012469.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 482539 lacG1 7685343 lacG1 Streptococcus pneumoniae Taiwan19F-14 6-phospho-beta-galactosidase YP_002742008.1 481127 D 487213 CDS YP_002742009.1 225860500 7686104 482608..484287 1 NC_012469.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) 484287 7686104 SPT_0519 Streptococcus pneumoniae Taiwan19F-14 pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) YP_002742009.1 482608 D 487213 CDS YP_002742010.1 225860501 7686916 complement(484413..485852) 1 NC_012469.1 identified by match to protein family HMM PF02386; potassium uptake protein, Trk family 485852 7686916 SPT_0520 Streptococcus pneumoniae Taiwan19F-14 potassium uptake protein, Trk family YP_002742010.1 484413 R 487213 CDS YP_002742011.1 225860502 7686302 complement(485856..487205) 1 NC_012469.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 487205 trkA 7686302 trkA Streptococcus pneumoniae Taiwan19F-14 potassium transporter peripheral membrane component YP_002742011.1 485856 R 487213 CDS YP_002742012.1 225860503 7685908 487393..488241 1 NC_012469.1 identified by match to protein family HMM PF01887; hypothetical protein 488241 7685908 SPT_0522 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742012.1 487393 D 487213 CDS YP_002742013.1 225860504 7687159 488256..488804 1 NC_012469.1 identified by match to protein family HMM PF07155; hypothetical protein 488804 7687159 SPT_0523 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742013.1 488256 D 487213 CDS YP_002742014.1 225860505 7686867 488811..489068 1 NC_012469.1 hypothetical protein 489068 7686867 SPT_0524 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742014.1 488811 D 487213 CDS YP_002742015.1 225860506 7686143 489170..490852 1 NC_012469.1 identified by match to protein family HMM PF00005; putative ABC transporter ATP-binding protein 490852 7686143 SPT_0525 Streptococcus pneumoniae Taiwan19F-14 putative ABC transporter ATP-binding protein YP_002742015.1 489170 D 487213 CDS YP_002742016.1 225860507 7687130 490837..491667 1 NC_012469.1 identified by match to protein family HMM PF02361; cobalt transport family protein 491667 7687130 SPT_0526 Streptococcus pneumoniae Taiwan19F-14 cobalt transport family protein YP_002742016.1 490837 D 487213 CDS YP_002742017.1 225860508 7686898 491860..492363 1 NC_012469.1 identified by match to protein family HMM PF00588; RNA methyltransferase, TrmH family, group 2 492363 7686898 SPT_0527 Streptococcus pneumoniae Taiwan19F-14 RNA methyltransferase, TrmH family, group 2 YP_002742017.1 491860 D 487213 CDS YP_002742018.1 225860509 7686064 492816..493379 1 NC_012469.1 hypothetical protein 493379 7686064 SPT_0528 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742018.1 492816 D 487213 CDS YP_002742019.1 225860510 7686968 493393..494019 1 NC_012469.1 identified by match to protein family HMM PF01569; PAP2 family protein 494019 7686968 SPT_0529 Streptococcus pneumoniae Taiwan19F-14 PAP2 family protein YP_002742019.1 493393 D 487213 CDS YP_002742020.1 225860511 7687150 494046..494435 1 NC_012469.1 hypothetical protein 494435 7687150 SPT_0530 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742020.1 494046 D 487213 CDS YP_002742021.1 225860512 7686016 494440..494889 1 NC_012469.1 hypothetical protein 494889 7686016 SPT_0531 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742021.1 494440 D 487213 CDS YP_002742022.1 225860513 7686606 495017..495604 1 NC_012469.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 495604 rpoE 7686606 rpoE Streptococcus pneumoniae Taiwan19F-14 DNA-directed RNA polymerase subunit delta YP_002742022.1 495017 D 487213 CDS YP_002742023.1 225860514 7686004 495994..497601 1 NC_012469.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 497601 pyrG 7686004 pyrG Streptococcus pneumoniae Taiwan19F-14 CTP synthetase YP_002742023.1 495994 D 487213 CDS YP_002742024.1 225860515 7687053 complement(498160..499791) 1 NC_012469.1 identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704; sodium-dependent phosphate transporter 499791 7687053 SPT_0534 Streptococcus pneumoniae Taiwan19F-14 sodium-dependent phosphate transporter YP_002742024.1 498160 R 487213 CDS YP_002742025.1 225860516 7686194 500152..505020 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF07501; match to protein family HMM PF07523; match to protein family HMM PF07554; match to protein family HMM TIGR01167; endo-beta-N-acetylglucosaminidase D 505020 7686194 SPT_0535 Streptococcus pneumoniae Taiwan19F-14 endo-beta-N-acetylglucosaminidase D YP_002742025.1 500152 D 487213 CDS YP_002742026.1 225860517 7687347 505110..506306 1 NC_012469.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 506306 pgk 7687347 pgk Streptococcus pneumoniae Taiwan19F-14 phosphoglycerate kinase YP_002742026.1 505110 D 487213 CDS YP_002742027.1 225860518 7686438 506442..506969 1 NC_012469.1 hypothetical protein 506969 7686438 SPT_0537 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742027.1 506442 D 487213 CDS YP_002742028.1 225860519 7686785 507046..507402 1 NC_012469.1 identified by match to protein family HMM PF00376; HTH-type transcriptional regulator GlnR 507402 7686785 SPT_0538 Streptococcus pneumoniae Taiwan19F-14 HTH-type transcriptional regulator GlnR YP_002742028.1 507046 D 487213 CDS YP_002742029.1 225860520 7686610 507439..508785 1 NC_012469.1 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 508785 glnA 7686610 glnA Streptococcus pneumoniae Taiwan19F-14 glutamine synthetase, type I YP_002742029.1 507439 D 487213 CDS YP_002742030.1 225860521 7686662 complement(508881..509000) 1 NC_012469.1 hypothetical protein 509000 7686662 SPT_0540 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742030.1 508881 R 487213 CDS YP_002742031.1 225860522 7685778 508965..509114 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 509114 7685778 SPT_0541 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742031.1 508965 D 487213 CDS YP_002742032.1 225860523 7686650 509567..510847 1 NC_012469.1 identified by match to protein family HMM PF01420; type I restriction enzyme specificity protein 510847 7686650 SPT_0543 Streptococcus pneumoniae Taiwan19F-14 type I restriction enzyme specificity protein YP_002742032.1 509567 D 487213 CDS YP_002742033.1 225860524 7686429 complement(510795..512360) 1 NC_012469.1 identified by match to protein family HMM PF01420; type I site-specific deoxyribonuclease chain S 512360 7686429 SPT_0542 Streptococcus pneumoniae Taiwan19F-14 type I site-specific deoxyribonuclease chain S YP_002742033.1 510795 R 487213 CDS YP_002742034.1 225860525 7685210 complement(512360..513823) 1 NC_012469.1 identified by match to protein family HMM PF02384; type I restriction enzyme 513823 7685210 SPT_0544 Streptococcus pneumoniae Taiwan19F-14 type I restriction enzyme YP_002742034.1 512360 R 487213 CDS YP_002742035.1 225860526 7686914 complement(513836..516169) 1 NC_012469.1 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463; type I restriction-modification system, R subunit 516169 7686914 SPT_0545 Streptococcus pneumoniae Taiwan19F-14 type I restriction-modification system, R subunit YP_002742035.1 513836 R 487213 CDS YP_002742036.1 225860527 7687254 complement(516520..516648) 1 NC_012469.1 hypothetical protein 516648 7687254 SPT_0546 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742036.1 516520 R 487213 CDS YP_002742037.1 225860528 7685825 516777..517286 1 NC_012469.1 hypothetical protein 517286 7685825 SPT_0547 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742037.1 516777 D 487213 CDS YP_002742038.1 225860529 7686547 517450..518484 1 NC_012469.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 518484 hrcA 7686547 hrcA Streptococcus pneumoniae Taiwan19F-14 heat-inducible transcription repressor YP_002742038.1 517450 D 487213 CDS YP_002742039.1 225860530 7685906 518511..519035 1 NC_012469.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 519035 grpE 7685906 grpE Streptococcus pneumoniae Taiwan19F-14 heat shock protein GrpE YP_002742039.1 518511 D 487213 CDS YP_002742040.1 225860531 7685969 519515..521338 1 NC_012469.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 521338 dnaK 7685969 dnaK Streptococcus pneumoniae Taiwan19F-14 molecular chaperone DnaK YP_002742040.1 519515 D 487213 CDS YP_002742041.1 225860532 7686007 521351..521704 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 521704 7686007 SPT_0551 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742041.1 521351 D 487213 CDS YP_002742042.1 225860533 7685453 521909..523045 1 NC_012469.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 523045 dnaJ 7685453 dnaJ Streptococcus pneumoniae Taiwan19F-14 chaperone protein DnaJ YP_002742042.1 521909 D 487213 CDS YP_002742043.1 225860534 7686268 complement(523367..523561) 1 NC_012469.1 chlorohydrolase 523561 7686268 SPT_0553 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742043.1 523367 R 487213 CDS YP_002742044.1 225860535 7687202 complement(523723..524010) 1 NC_012469.1 hypothetical protein 524010 7687202 SPT_0554 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742044.1 523723 R 487213 CDS YP_002742045.1 225860536 7685912 complement(524020..524430) 1 NC_012469.1 identified by match to protein family HMM PF01230; histidine triad domain protein 524430 7685912 SPT_0555 Streptococcus pneumoniae Taiwan19F-14 histidine triad domain protein YP_002742045.1 524020 R 487213 CDS YP_002742046.1 225860537 7686175 524498..525229 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 525229 7686175 SPT_0556 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742046.1 524498 D 487213 CDS YP_002742047.1 225860538 7687090 525226..526275 1 NC_012469.1 identified by match to protein family HMM PF05975; ABC transporter permease 526275 7687090 SPT_0557 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002742047.1 525226 D 487213 CDS YP_002742048.1 225860539 7686746 complement(526443..526772) 1 NC_012469.1 BlpT protein, fusion 526772 7686746 SPT_0558 Streptococcus pneumoniae Taiwan19F-14 BlpT protein, fusion YP_002742048.1 526443 R 487213 CDS YP_002742049.1 225860540 7685662 complement(527068..528414) 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 528414 7685662 SPT_0559 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742049.1 527068 R 487213 CDS YP_002742050.1 225860541 7686336 528756..529094 1 NC_012469.1 identified by match to protein family HMM PF04397; BlpS protein 529094 7686336 SPT_0560 Streptococcus pneumoniae Taiwan19F-14 BlpS protein YP_002742050.1 528756 D 487213 CDS YP_002742051.1 225860542 7686639 529099..529836 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 529836 7686639 SPT_0561 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002742051.1 529099 D 487213 CDS YP_002742052.1 225860543 7686631 529849..531189 1 NC_012469.1 histidine kinase 531189 7686631 SPT_0562 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002742052.1 529849 D 487213 CDS YP_002742053.1 225860544 7685318 complement(531429..532775) 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 532775 7685318 SPT_0563 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742053.1 531429 R 487213 CDS YP_002742054.1 225860545 7687178 complement(532942..533097) 1 NC_012469.1 identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein 533097 7687178 SPT_0564 Streptococcus pneumoniae Taiwan19F-14 bacteriocin-type signal sequence domain protein YP_002742054.1 532942 R 487213 CDS YP_002742055.1 225860546 7685454 complement(533154..534515) 1 NC_012469.1 identified by match to protein family HMM TIGR01000; BlpC ABC transporter 534515 7685454 SPT_0565 Streptococcus pneumoniae Taiwan19F-14 BlpC ABC transporter YP_002742055.1 533154 R 487213 CDS YP_002742056.1 225860547 7685414 536059..536307 1 NC_012469.1 identified by match to protein family HMM TIGR01847; hypothetical protein 536307 7685414 SPT_0568 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742056.1 536059 D 487213 CDS YP_002742057.1 225860548 7687373 536323..536532 1 NC_012469.1 identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein 536532 7687373 SPT_0569 Streptococcus pneumoniae Taiwan19F-14 bacteriocin-type signal sequence domain protein YP_002742057.1 536323 D 487213 CDS YP_002742058.1 225860549 7687073 537734..538309 1 NC_012469.1 identified by match to protein family HMM PF02517; ABC transporter ATP-binding protein 538309 7687073 SPT_0570 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742058.1 537734 D 487213 CDS YP_002742059.1 225860550 7687307 538536..538724 1 NC_012469.1 hypothetical protein 538724 7687307 SPT_0571 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742059.1 538536 D 487213 CDS YP_002742060.1 225860551 7687224 538820..539158 1 NC_012469.1 immunity protein BlpL 539158 7687224 SPT_0572 Streptococcus pneumoniae Taiwan19F-14 immunity protein BlpL YP_002742060.1 538820 D 487213 CDS YP_002742061.1 225860552 7686500 540314..540547 1 NC_012469.1 identified by match to protein family HMM TIGR01847; bacteriocin BlpM 540547 7686500 SPT_0576 Streptococcus pneumoniae Taiwan19F-14 bacteriocin BlpM YP_002742061.1 540314 D 487213 CDS YP_002742062.1 225860553 7685473 541056..541745 1 NC_012469.1 BlpY protein 541745 7685473 SPT_0577 Streptococcus pneumoniae Taiwan19F-14 BlpY protein YP_002742062.1 541056 D 487213 CDS YP_002742063.1 225860554 7685995 542171..542782 1 NC_012469.1 identified by match to protein family HMM PF02517; ABC transporter ATP-binding protein 542782 7685995 SPT_0579 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742063.1 542171 D 487213 CDS YP_002742064.1 225860555 7686583 542943..543737 1 NC_012469.1 identified by match to protein family HMM PF01636; phosphotransferase enzyme family 543737 7686583 SPT_0580 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase enzyme family YP_002742064.1 542943 D 487213 CDS YP_002742065.1 225860556 7685638 543734..544369 1 NC_012469.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 544369 trmB 7685638 trmB Streptococcus pneumoniae Taiwan19F-14 tRNA (guanine-N(7)-)-methyltransferase YP_002742065.1 543734 D 487213 CDS YP_002742066.1 225860557 7686085 544495..544974 1 NC_012469.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 544974 7686085 SPT_0582 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742066.1 544495 D 487213 CDS YP_002742067.1 225860558 7685714 545018..546154 1 NC_012469.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 546154 nusA 7685714 nusA Streptococcus pneumoniae Taiwan19F-14 transcription elongation factor NusA YP_002742067.1 545018 D 487213 CDS YP_002742068.1 225860559 7686503 546176..546469 1 NC_012469.1 identified by match to protein family HMM PF04296; putative chain a, hypothetical cytosolic protein coded by gene from nusainfb, ylxr homologue 546469 7686503 SPT_0584 Streptococcus pneumoniae Taiwan19F-14 putative chain a, hypothetical cytosolic protein coded by gene from nusainfb, ylxr homologue YP_002742068.1 546176 D 487213 CDS YP_002742069.1 225860560 7687096 546462..546761 1 NC_012469.1 identified by match to protein family HMM PF01248; hypothetical protein 546761 7687096 SPT_0585 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742069.1 546462 D 487213 CDS YP_002742070.1 225860561 7687047 546778..549570 1 NC_012469.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 549570 infB 7687047 infB Streptococcus pneumoniae Taiwan19F-14 translation initiation factor IF-2 YP_002742070.1 546778 D 487213 CDS YP_002742071.1 225860562 7686021 549821..550171 1 NC_012469.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 550171 rbfA 7686021 rbfA Streptococcus pneumoniae Taiwan19F-14 ribosome-binding factor A YP_002742071.1 549821 D 487213 CDS YP_002742072.1 225860563 7686420 550450..551229 1 NC_012469.1 hypothetical protein 551229 7686420 SPT_0588 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742072.1 550450 D 487213 CDS YP_002742073.1 225860564 7685441 551231..551413 1 NC_012469.1 hypothetical protein 551413 7685441 SPT_0589 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742073.1 551231 D 487213 CDS YP_002742074.1 225860565 7686792 551410..551562 1 NC_012469.1 hypothetical protein 551562 7686792 SPT_0590 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742074.1 551410 D 487213 CDS YP_002742075.1 225860566 7685933 complement(551692..551844) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 551844 7685933 SPT_0591 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742075.1 551692 R 487213 CDS YP_002742076.1 225860567 7685940 551875..552108 1 NC_012469.1 identified by match to protein family HMM PF08984; hypothetical protein 552108 7685940 SPT_0592 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742076.1 551875 D 487213 CDS YP_002742077.1 225860568 7687249 552108..553442 1 NC_012469.1 identified by match to protein family HMM PF01814; match to protein family HMM PF04282; hemerythrin HHE cation binding domain subfamily, putative 553442 7687249 SPT_0593 Streptococcus pneumoniae Taiwan19F-14 hemerythrin HHE cation binding domain subfamily, putative YP_002742077.1 552108 D 487213 CDS YP_002742078.1 225860569 7685298 553452..553706 1 NC_012469.1 identified by match to protein family HMM PF08930; hypothetical protein 553706 7685298 SPT_0594 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742078.1 553452 D 487213 CDS YP_002742079.1 225860570 7686813 553802..554197 1 NC_012469.1 superfamily II helicase 554197 7686813 SPT_0595 Streptococcus pneumoniae Taiwan19F-14 superfamily II helicase YP_002742079.1 553802 D 487213 CDS YP_002742080.1 225860571 7685371 554610..555059 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 555059 7685371 SPT_0596 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742080.1 554610 D 487213 CDS YP_002742081.1 225860572 7685249 555046..555606 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 555606 7685249 SPT_0597 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742081.1 555046 D 487213 CDS YP_002742082.1 225860573 7686091 555606..556184 1 NC_012469.1 shikimate kinase 556184 7686091 SPT_0598 Streptococcus pneumoniae Taiwan19F-14 shikimate kinase YP_002742082.1 555606 D 487213 CDS YP_002742083.1 225860574 7686882 556177..558828 1 NC_012469.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 558828 valS 7686882 valS Streptococcus pneumoniae Taiwan19F-14 valyl-tRNA synthetase YP_002742083.1 556177 D 487213 CDS YP_002742084.1 225860575 7686483 558909..559073 1 NC_012469.1 hypothetical protein 559073 7686483 SPT_0600 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742084.1 558909 D 487213 CDS YP_002742085.1 225860576 7686947 561106..561909 1 NC_012469.1 identified by match to protein family HMM PF02661; Fic protein family 561909 7686947 SPT_0602 Streptococcus pneumoniae Taiwan19F-14 Fic protein family YP_002742085.1 561106 D 487213 CDS YP_002742086.1 225860577 7686133 complement(562025..562858) 1 NC_012469.1 identified by match to protein family HMM PF00665; integrase core domain protein 562858 7686133 SPT_0603 Streptococcus pneumoniae Taiwan19F-14 integrase core domain protein YP_002742086.1 562025 R 487213 CDS YP_002742087.1 225860578 7686790 563356..563538 1 NC_012469.1 hypothetical protein 563538 7686790 SPT_0605 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742087.1 563356 D 487213 CDS YP_002742088.1 225860579 7685803 563838..564677 1 NC_012469.1 transcription antiterminator LicT 564677 7685803 SPT_0606 Streptococcus pneumoniae Taiwan19F-14 transcription antiterminator LicT YP_002742088.1 563838 D 487213 CDS YP_002742089.1 225860580 7687374 564695..566533 1 NC_012469.1 pts system beta-glucoside-specific eiibca component (eiibca-bgl) (eii-bgl) 566533 7687374 SPT_0607 Streptococcus pneumoniae Taiwan19F-14 pts system beta-glucoside-specific eiibca component (eiibca-bgl) (eii-bgl) YP_002742089.1 564695 D 487213 CDS YP_002742090.1 225860581 7686713 566546..567961 1 NC_012469.1 identified by match to protein family HMM PF00232; beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase) 567961 7686713 SPT_0608 Streptococcus pneumoniae Taiwan19F-14 beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase) YP_002742090.1 566546 D 487213 CDS YP_002742091.1 225860582 7685802 568511..569599 1 NC_012469.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 569599 pheS 7685802 pheS Streptococcus pneumoniae Taiwan19F-14 phenylalanyl-tRNA synthetase subunit alpha YP_002742091.1 568511 D 487213 CDS YP_002742092.1 225860583 7687075 569599..570108 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 570108 7687075 SPT_0610 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742092.1 569599 D 487213 CDS YP_002742093.1 225860584 7685221 570185..572590 1 NC_012469.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 572590 pheT 7685221 pheT Streptococcus pneumoniae Taiwan19F-14 phenylalanyl-tRNA synthetase subunit beta YP_002742093.1 570185 D 487213 CDS YP_002742094.1 225860585 7686374 complement(572658..573659) 1 NC_012469.1 identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family 573659 7686374 SPT_0612 Streptococcus pneumoniae Taiwan19F-14 endonuclease/exonuclease/phosphatase family YP_002742094.1 572658 R 487213 CDS YP_002742095.1 225860586 7686954 574335..574601 1 NC_012469.1 identified by match to protein family HMM PF01381; helix-turn-helix domain protein 574601 7686954 SPT_0614 Streptococcus pneumoniae Taiwan19F-14 helix-turn-helix domain protein YP_002742095.1 574335 D 487213 CDS YP_002742096.1 225860587 7686738 574862..577111 1 NC_012469.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 577111 metE 7686738 metE Streptococcus pneumoniae Taiwan19F-14 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase YP_002742096.1 574862 D 487213 CDS YP_002742097.1 225860588 7686258 577175..578041 1 NC_012469.1 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 578041 metF 7686258 metF Streptococcus pneumoniae Taiwan19F-14 5,10-methylenetetrahydrofolate reductase YP_002742097.1 577175 D 487213 CDS YP_002742098.1 225860589 7687318 578726..580939 1 NC_012469.1 identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase/polyadenylase 580939 7687318 SPT_0617 Streptococcus pneumoniae Taiwan19F-14 polynucleotide phosphorylase/polyadenylase YP_002742098.1 578726 D 487213 CDS YP_002742099.1 225860590 7685396 580955..581572 1 NC_012469.1 identified by match to protein family HMM TIGR01172; serine O-acetyltransferase 581572 cysE 7685396 cysE Streptococcus pneumoniae Taiwan19F-14 serine O-acetyltransferase YP_002742099.1 580955 D 487213 CDS YP_002742100.1 225860591 7685363 581584..582468 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 582468 7685363 SPT_0619 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742100.1 581584 D 487213 CDS YP_002742101.1 225860592 7686819 582555..583898 1 NC_012469.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 583898 cysS 7686819 cysS Streptococcus pneumoniae Taiwan19F-14 cysteinyl-tRNA synthetase YP_002742101.1 582555 D 487213 CDS YP_002742102.1 225860593 7685372 583891..584277 1 NC_012469.1 identified by match to protein family HMM PF00636; ribonuclease III family protein 584277 7685372 SPT_0621 Streptococcus pneumoniae Taiwan19F-14 ribonuclease III family protein YP_002742102.1 583891 D 487213 CDS YP_002742103.1 225860594 7685235 584281..585165 1 NC_012469.1 leucine-rich protein 585165 7685235 SPT_0622 Streptococcus pneumoniae Taiwan19F-14 leucine-rich protein YP_002742103.1 584281 D 487213 CDS YP_002742104.1 225860595 7685937 585213..585329 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 585329 7685937 SPT_0623 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742104.1 585213 D 487213 CDS YP_002742105.1 225860596 7686794 585302..585901 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 585901 7686794 SPT_0624 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742105.1 585302 D 487213 CDS YP_002742106.1 225860597 7685278 586047..586220 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 586220 7685278 SPT_0625 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742106.1 586047 D 487213 CDS YP_002742107.1 225860598 7685559 586571..587848 1 NC_012469.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 587848 7685559 SPT_0626 Streptococcus pneumoniae Taiwan19F-14 peptide ABC transporter permease YP_002742107.1 586571 D 487213 CDS YP_002742108.1 225860599 7685922 587861..588508 1 NC_012469.1 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 588508 7685922 SPT_0627 Streptococcus pneumoniae Taiwan19F-14 peptide ABC transporter ATP-binding protein YP_002742108.1 587861 D 487213 CDS YP_002742109.1 225860600 7685498 588560..589939 1 NC_012469.1 identified by match to protein family HMM PF02687; peptide ABC transporter permease 589939 7685498 SPT_0628 Streptococcus pneumoniae Taiwan19F-14 peptide ABC transporter permease YP_002742109.1 588560 D 487213 CDS YP_002742110.1 225860601 7687316 590250..590906 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; VncR, response regulator 590906 7687316 SPT_0629 Streptococcus pneumoniae Taiwan19F-14 VncR, response regulator YP_002742110.1 590250 D 487213 CDS YP_002742111.1 225860602 7685369 590903..592231 1 NC_012469.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; VncS, histidine kinase 592231 7685369 SPT_0630 Streptococcus pneumoniae Taiwan19F-14 VncS, histidine kinase YP_002742111.1 590903 D 487213 CDS YP_002742112.1 225860603 7686286 592372..593253 1 NC_012469.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 593253 7686286 SPT_0631 Streptococcus pneumoniae Taiwan19F-14 fructose-bisphosphate aldolase YP_002742112.1 592372 D 487213 CDS YP_002742113.1 225860604 7686499 complement(593574..594764) 1 NC_012469.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF01794; oxidoreductase, NAD-binding 594764 7686499 SPT_0632 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase, NAD-binding YP_002742113.1 593574 R 487213 CDS YP_002742114.1 225860605 7686976 complement(594908..595567) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 595567 7686976 SPT_0633 Streptococcus pneumoniae Taiwan19F-14 glutamine ABC transporter permease YP_002742114.1 594908 R 487213 CDS YP_002742115.1 225860606 7686369 complement(595577..596254) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 596254 7686369 SPT_0634 Streptococcus pneumoniae Taiwan19F-14 glutamine ABC transporter permease YP_002742115.1 595577 R 487213 CDS YP_002742116.1 225860607 7685286 complement(596267..597061) 1 NC_012469.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor 597061 7685286 SPT_0635 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor YP_002742116.1 596267 R 487213 CDS YP_002742117.1 225860608 7685716 complement(597072..597830) 1 NC_012469.1 identified by match to protein family HMM PF00005; ATP-binding protein 597830 7685716 SPT_0636 Streptococcus pneumoniae Taiwan19F-14 ATP-binding protein YP_002742117.1 597072 R 487213 CDS YP_002742118.1 225860609 7685997 598107..600329 1 NC_012469.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 600329 recJ 7685997 recJ Streptococcus pneumoniae Taiwan19F-14 single-stranded-DNA-specific exonuclease RecJ YP_002742118.1 598107 D 487213 CDS YP_002742119.1 225860610 7685816 600504..602165 1 NC_012469.1 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; metallo-beta-lactamase family protein 602165 7685816 SPT_0638 Streptococcus pneumoniae Taiwan19F-14 metallo-beta-lactamase family protein YP_002742119.1 600504 D 487213 CDS YP_002742120.1 225860611 7686288 602234..603013 1 NC_012469.1 identified by match to protein family HMM PF00756; tributyrin esterase 603013 7686288 SPT_0639 Streptococcus pneumoniae Taiwan19F-14 tributyrin esterase YP_002742120.1 602234 D 487213 CDS YP_002742121.1 225860612 7686100 603125..604345 1 NC_012469.1 identified by match to protein family HMM PF02388; serine/alanine-adding enzyme MurM 604345 7686100 SPT_0640 Streptococcus pneumoniae Taiwan19F-14 serine/alanine-adding enzyme MurM YP_002742121.1 603125 D 487213 CDS YP_002742122.1 225860613 7685651 604350..605582 1 NC_012469.1 identified by match to protein family HMM PF02388; alanine-adding enzyme MurN 605582 7685651 SPT_0641 Streptococcus pneumoniae Taiwan19F-14 alanine-adding enzyme MurN YP_002742122.1 604350 D 487213 CDS YP_002742123.1 225860614 7686629 605661..606362 1 NC_012469.1 identified by match to protein family HMM PF00413; matrixin family 606362 7686629 SPT_0642 Streptococcus pneumoniae Taiwan19F-14 matrixin family YP_002742123.1 605661 D 487213 CDS YP_002742124.1 225860615 7687072 606402..608246 1 NC_012469.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 608246 uvrC 7687072 uvrC Streptococcus pneumoniae Taiwan19F-14 excinuclease ABC subunit C YP_002742124.1 606402 D 487213 CDS YP_002742125.1 225860616 7687306 608278..609069 1 NC_012469.1 hypothetical protein 609069 7687306 SPT_0644 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742125.1 608278 D 487213 CDS YP_002742126.1 225860617 7686308 complement(609251..610051) 1 NC_012469.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor 610051 7686308 SPT_0645 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor YP_002742126.1 609251 R 487213 CDS YP_002742127.1 225860618 7685504 610222..610827 1 NC_012469.1 identified by match to protein family HMM PF00881; oxidoreductase 610827 7685504 SPT_0646 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase YP_002742127.1 610222 D 487213 CDS YP_002742128.1 225860619 7686240 610840..612240 1 NC_012469.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 612240 pepV 7686240 pepV Streptococcus pneumoniae Taiwan19F-14 dipeptidase PepV YP_002742128.1 610840 D 487213 CDS YP_002742129.1 225860620 7686652 612294..612872 1 NC_012469.1 identified by match to protein family HMM PF03167; uracil DNA glycosylase family protein 612872 7686652 SPT_0648 Streptococcus pneumoniae Taiwan19F-14 uracil DNA glycosylase family protein YP_002742129.1 612294 D 487213 CDS YP_002742130.1 225860621 7685622 613032..613184 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 613184 7685622 SPT_0649 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742130.1 613032 D 487213 CDS YP_002742131.1 225860622 7686209 613200..613319 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 613319 7686209 SPT_0650 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742131.1 613200 D 487213 CDS YP_002742132.1 225860623 7687389 613490..614815 1 NC_012469.1 branched-chain amino acid transport system II carrier protein 614815 7687389 SPT_0651 Streptococcus pneumoniae Taiwan19F-14 branched-chain amino acid transport system II carrier protein YP_002742132.1 613490 D 487213 CDS YP_002742133.1 225860624 7685392 614913..615950 1 NC_012469.1 identified by match to protein family HMM PF05343; peptidase, M42 615950 7685392 SPT_0652 Streptococcus pneumoniae Taiwan19F-14 peptidase, M42 YP_002742133.1 614913 D 487213 CDS YP_002742134.1 225860625 7686586 615952..616413 1 NC_012469.1 identified by match to protein family HMM PF01230; HIT family protein 616413 7686586 SPT_0653 Streptococcus pneumoniae Taiwan19F-14 HIT family protein YP_002742134.1 615952 D 487213 CDS YP_002742135.1 225860626 7685277 616431..617147 1 NC_012469.1 D-alanyl-D-alanine carboxypeptidase 617147 7685277 SPT_0654 Streptococcus pneumoniae Taiwan19F-14 D-alanyl-D-alanine carboxypeptidase YP_002742135.1 616431 D 487213 CDS YP_002742136.1 225860627 7686165 complement(617187..617324) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 617324 7686165 SPT_0655 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742136.1 617187 R 487213 CDS YP_002742137.1 225860628 7686473 617456..617881 1 NC_012469.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 617881 rplK 7686473 rplK Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L11 YP_002742137.1 617456 D 487213 CDS YP_002742138.1 225860629 7686386 618089..618778 1 NC_012469.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 618778 rplA 7686386 rplA Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L1 YP_002742138.1 618089 D 487213 CDS YP_002742139.1 225860630 7685556 complement(619370..619516) 1 NC_012469.1 chlorohydrolase 619516 7685556 SPT_0658 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742139.1 619370 R 487213 CDS YP_002742140.1 225860631 7686276 619674..619892 1 NC_012469.1 hypothetical protein 619892 7686276 SPT_0659 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742140.1 619674 D 487213 CDS YP_002742141.1 225860632 7685405 620291..620527 1 NC_012469.1 hypothetical protein 620527 7685405 SPT_0660 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742141.1 620291 D 487213 CDS YP_002742142.1 225860633 7686260 620937..621929 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 621929 7686260 SPT_0661 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742142.1 620937 D 487213 CDS YP_002742143.1 225860634 7686162 621931..622749 1 NC_012469.1 identified by match to protein family HMM PF06182; membrane protein 622749 7686162 SPT_0662 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002742143.1 621931 D 487213 CDS YP_002742144.1 225860635 7686557 622751..623536 1 NC_012469.1 identified by match to protein family HMM PF06182; ABC transporter permease 623536 7686557 SPT_0663 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002742144.1 622751 D 487213 CDS YP_002742145.1 225860636 7686274 624768..631199 1 NC_012469.1 identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF05922; match to protein family HMM PF06280; match to protein family HMM TIGR01167; serine protease 631199 7686274 SPT_0666 Streptococcus pneumoniae Taiwan19F-14 serine protease YP_002742145.1 624768 D 487213 CDS YP_002742146.1 225860637 7686600 631831..632307 1 NC_012469.1 identified by match to protein family HMM PF00359; phosphotransferase system sugar-specific EII component 632307 7686600 SPT_0667 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002742146.1 631831 D 487213 CDS YP_002742147.1 225860638 7685684 632345..632650 1 NC_012469.1 PTS system, galactose-specific IIB component 632650 7685684 SPT_0668 Streptococcus pneumoniae Taiwan19F-14 PTS system, galactose-specific IIB component YP_002742147.1 632345 D 487213 CDS YP_002742148.1 225860639 7686956 632698..634173 1 NC_012469.1 phosphotransferase system sugar-specific EII component 634173 7686956 SPT_0669 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002742148.1 632698 D 487213 CDS YP_002742149.1 225860640 7686051 634568..641269 1 NC_012469.1 identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-galactosidase 641269 7686051 SPT_0670 Streptococcus pneumoniae Taiwan19F-14 beta-galactosidase YP_002742149.1 634568 D 487213 CDS YP_002742150.1 225860641 7686854 complement(641517..641747) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 641747 7686854 SPT_0671 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742150.1 641517 R 487213 CDS YP_002742151.1 225860642 7687131 complement(641716..642129) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 642129 7687131 SPT_0672 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742151.1 641716 R 487213 CDS YP_002742152.1 225860643 7685262 complement(642129..642374) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 642374 7685262 SPT_0673 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742152.1 642129 R 487213 CDS YP_002742153.1 225860644 7686769 complement(642585..642944) 1 NC_012469.1 integral membrane protein 642944 7686769 SPT_0674 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002742153.1 642585 R 487213 CDS YP_002742154.1 225860645 7686995 643977..644534 1 NC_012469.1 identified by match to protein family HMM PF06962; SAM-dependent methyltransferase 644534 7686995 SPT_0677 Streptococcus pneumoniae Taiwan19F-14 SAM-dependent methyltransferase YP_002742154.1 643977 D 487213 CDS YP_002742155.1 225860646 7685712 644527..644781 1 NC_012469.1 hypothetical protein 644781 7685712 SPT_0678 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742155.1 644527 D 487213 CDS YP_002742156.1 225860647 7686934 644793..646847 1 NC_012469.1 identified by match to protein family HMM PF00999; sodium/hydrogen exchanger family protein 646847 7686934 SPT_0679 Streptococcus pneumoniae Taiwan19F-14 sodium/hydrogen exchanger family protein YP_002742156.1 644793 D 487213 CDS YP_002742157.1 225860648 7687106 647026..647886 1 NC_012469.1 identified by match to protein family HMM PF03631; ribonuclease BN 647886 7687106 SPT_0680 Streptococcus pneumoniae Taiwan19F-14 ribonuclease BN YP_002742157.1 647026 D 487213 CDS YP_002742158.1 225860649 7686655 648097..648807 1 NC_012469.1 identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein 648807 7686655 SPT_0682 Streptococcus pneumoniae Taiwan19F-14 cytochrome c-type biogenesis protein YP_002742158.1 648097 D 487213 CDS YP_002742159.1 225860650 7686215 648827..649393 1 NC_012469.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 649393 7686215 SPT_0683 Streptococcus pneumoniae Taiwan19F-14 thioredoxin family protein YP_002742159.1 648827 D 487213 CDS YP_002742160.1 225860651 7687360 649404..650516 1 NC_012469.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 650516 7687360 SPT_0684 Streptococcus pneumoniae Taiwan19F-14 peptide methionine sulfoxide reductase MsrA/msrB YP_002742160.1 649404 D 487213 CDS YP_002742161.1 225860652 7685959 650739..651476 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 651476 7685959 SPT_0685 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002742161.1 650739 D 487213 CDS YP_002742162.1 225860653 7686220 651473..653164 1 NC_012469.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580; histidine kinase 653164 7686220 SPT_0686 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002742162.1 651473 D 487213 CDS YP_002742163.1 225860654 7685241 653280..653843 1 NC_012469.1 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440; hypothetical protein 653843 7685241 SPT_0687 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742163.1 653280 D 487213 CDS YP_002742164.1 225860655 7686335 653865..659573 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; zinc metalloprotease ZmpB 659573 zmpB 7686335 zmpB Streptococcus pneumoniae Taiwan19F-14 zinc metalloprotease ZmpB YP_002742164.1 653865 D 487213 CDS YP_002742165.1 225860656 7685694 659634..661355 1 NC_012469.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553; chorismate binding enzyme 661355 7685694 SPT_0689 Streptococcus pneumoniae Taiwan19F-14 chorismate binding enzyme YP_002742165.1 659634 D 487213 CDS YP_002742166.1 225860657 7685260 661356..661973 1 NC_012469.1 hypothetical protein 661973 7685260 SPT_0690 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742166.1 661356 D 487213 CDS YP_002742167.1 225860658 7687359 662023..663021 1 NC_012469.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05901; match to protein family HMM PF07553; hypothetical protein 663021 7687359 SPT_0691 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742167.1 662023 D 487213 CDS YP_002742168.1 225860659 7685801 663148..664107 1 NC_012469.1 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744; glucokinase (Glucose kinase) 664107 7685801 SPT_0692 Streptococcus pneumoniae Taiwan19F-14 glucokinase (Glucose kinase) YP_002742168.1 663148 D 487213 CDS YP_002742169.1 225860660 7686588 664204..665043 1 NC_012469.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 665043 thyA 7686588 thyA Streptococcus pneumoniae Taiwan19F-14 thymidylate synthase YP_002742169.1 664204 D 487213 CDS YP_002742170.1 225860661 7685654 complement(665090..665260) 1 NC_012469.1 hypothetical protein 665260 7685654 SPT_0694 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742170.1 665090 R 487213 CDS YP_002742171.1 225860662 7687000 665381..666265 1 NC_012469.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 666265 miaA 7687000 miaA Streptococcus pneumoniae Taiwan19F-14 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002742171.1 665381 D 487213 CDS YP_002742172.1 225860663 7686508 666258..667496 1 NC_012469.1 identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156; GTP-binding proten HflX 667496 hflX 7686508 hflX Streptococcus pneumoniae Taiwan19F-14 GTP-binding proten HflX YP_002742172.1 666258 D 487213 CDS YP_002742173.1 225860664 7686251 667489..668112 1 NC_012469.1 cystathionine beta-lyase 668112 7686251 SPT_0697 Streptococcus pneumoniae Taiwan19F-14 cystathionine beta-lyase YP_002742173.1 667489 D 487213 CDS YP_002742174.1 225860665 7685963 668127..669056 1 NC_012469.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 669056 rnz 7685963 rnz Streptococcus pneumoniae Taiwan19F-14 ribonuclease Z YP_002742174.1 668127 D 487213 CDS YP_002742175.1 225860666 7686494 669077..669832 1 NC_012469.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; oxidoreductase 669832 7686494 SPT_0699 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase YP_002742175.1 669077 D 487213 CDS YP_002742176.1 225860667 7685254 complement(669886..670854) 1 NC_012469.1 identified by match to protein family HMM PF00126; regulatory function on capsule expression 670854 7685254 SPT_0700 Streptococcus pneumoniae Taiwan19F-14 regulatory function on capsule expression YP_002742176.1 669886 R 487213 CDS YP_002742177.1 225860668 7685695 670858..671127 1 NC_012469.1 identified by match to protein family HMM PF06014; hypothetical protein 671127 7685695 SPT_0701 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742177.1 670858 D 487213 CDS YP_002742178.1 225860669 7686992 671127..671507 1 NC_012469.1 identified by match to protein family HMM PF00581; rhodanese family protein 671507 7686992 SPT_0702 Streptococcus pneumoniae Taiwan19F-14 rhodanese family protein YP_002742178.1 671127 D 487213 CDS YP_002742179.1 225860670 7686017 671596..671823 1 NC_012469.1 hypothetical protein 671823 7686017 SPT_0703 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742179.1 671596 D 487213 CDS YP_002742180.1 225860671 7687054 complement(671863..672588) 1 NC_012469.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A, putative 672588 7687054 SPT_0704 Streptococcus pneumoniae Taiwan19F-14 ribosomal small subunit pseudouridine synthase A, putative YP_002742180.1 671863 R 487213 CDS YP_002742181.1 225860672 7686905 672750..674591 1 NC_012469.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA/BipA 674591 typA 7686905 typA Streptococcus pneumoniae Taiwan19F-14 GTP-binding protein TypA/BipA YP_002742181.1 672750 D 487213 CDS YP_002742182.1 225860673 7686357 674611..674865 1 NC_012469.1 hypothetical protein 674865 7686357 SPT_0706 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742182.1 674611 D 487213 CDS YP_002742183.1 225860674 7686136 675230..675529 1 NC_012469.1 identified by match to protein family HMM TIGR01653; bacteriocin, lactococcin 972 family 675529 7686136 SPT_0707 Streptococcus pneumoniae Taiwan19F-14 bacteriocin, lactococcin 972 family YP_002742183.1 675230 D 487213 CDS YP_002742184.1 225860675 7685838 675600..677621 1 NC_012469.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 677621 7685838 SPT_0708 Streptococcus pneumoniae Taiwan19F-14 bacteriocin-associated integral membrane protein YP_002742184.1 675600 D 487213 CDS YP_002742185.1 225860676 7685321 677623..678264 1 NC_012469.1 identified by match to protein family HMM PF00005; Na+ ABC transporter ATP-binding protein 678264 7685321 SPT_0709 Streptococcus pneumoniae Taiwan19F-14 Na+ ABC transporter ATP-binding protein YP_002742185.1 677623 D 487213 CDS YP_002742186.1 225860677 7686078 678368..679720 1 NC_012469.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 679720 murD 7686078 murD Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002742186.1 678368 D 487213 CDS YP_002742187.1 225860678 7687006 679722..680780 1 NC_012469.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 680780 murG 7687006 murG Streptococcus pneumoniae Taiwan19F-14 UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase YP_002742187.1 679722 D 487213 CDS YP_002742188.1 225860679 7687382 680790..682010 1 NC_012469.1 identified by match to protein family HMM PF03799; match to protein family HMM PF08478; cell division protein DivIB 682010 7687382 SPT_0712 Streptococcus pneumoniae Taiwan19F-14 cell division protein DivIB YP_002742188.1 680790 D 487213 CDS YP_002742189.1 225860680 7686876 682243..682944 1 NC_012469.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 682944 pyrF 7686876 pyrF Streptococcus pneumoniae Taiwan19F-14 orotidine 5'-phosphate decarboxylase YP_002742189.1 682243 D 487213 CDS YP_002742190.1 225860681 7685283 682978..683610 1 NC_012469.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 683610 pyrE 7685283 pyrE Streptococcus pneumoniae Taiwan19F-14 orotate phosphoribosyltransferase YP_002742190.1 682978 D 487213 CDS YP_002742191.1 225860682 7686938 684071..684193 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 684193 7686938 SPT_0715 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742191.1 684071 D 487213 CDS YP_002742192.1 225860683 7687177 684289..685053 1 NC_012469.1 hypothetical protein 685053 7687177 SPT_0716 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742192.1 684289 D 487213 CDS YP_002742193.1 225860684 7685850 685002..685535 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 685535 7685850 SPT_0717 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742193.1 685002 D 487213 CDS YP_002742194.1 225860685 7686190 685808..686512 1 NC_012469.1 hypothetical protein 686512 7686190 SPT_0718 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742194.1 685808 D 487213 CDS YP_002742195.1 225860686 7685470 686509..687156 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 687156 7685470 SPT_0719 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742195.1 686509 D 487213 CDS YP_002742196.1 225860687 7685375 complement(688871..689062) 1 NC_012469.1 glutamine ABC transporter permease 689062 7685375 SPT_0723 Streptococcus pneumoniae Taiwan19F-14 glutamine ABC transporter permease YP_002742196.1 688871 R 487213 CDS YP_002742197.1 225860688 7686666 complement(690634..691257) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 691257 7686666 SPT_0726 Streptococcus pneumoniae Taiwan19F-14 glutamine ABC transporter permease YP_002742197.1 690634 R 487213 CDS YP_002742198.1 225860689 7686990 complement(691217..691897) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease 691897 7686990 SPT_0727 Streptococcus pneumoniae Taiwan19F-14 glutamine ABC transporter permease YP_002742198.1 691217 R 487213 CDS YP_002742199.1 225860690 7686107 692112..692258 1 NC_012469.1 hypothetical protein 692258 7686107 SPT_0728 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742199.1 692112 D 487213 CDS YP_002742200.1 225860691 7685201 692386..693876 1 NC_012469.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 693876 lysS 7685201 lysS Streptococcus pneumoniae Taiwan19F-14 lysyl-tRNA synthetase YP_002742200.1 692386 D 487213 CDS YP_002742201.1 225860692 7686704 694296..695642 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 695642 7686704 SPT_0730 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742201.1 694296 D 487213 CDS YP_002742202.1 225860693 7687291 696209..697345 1 NC_012469.1 identified by match to protein family HMM PF01070; match to protein family HMM TIGR02708; L-lactate oxidase 697345 lctO 7687291 lctO Streptococcus pneumoniae Taiwan19F-14 L-lactate oxidase YP_002742202.1 696209 D 487213 CDS YP_002742203.1 225860694 7685818 697901..698569 1 NC_012469.1 identified by match to protein family HMM PF03070; tena/thi-4 family 698569 7685818 SPT_0732 Streptococcus pneumoniae Taiwan19F-14 tena/thi-4 family YP_002742203.1 697901 D 487213 CDS YP_002742204.1 225860695 7686535 698806..699588 1 NC_012469.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 699588 thiM 7686535 thiM Streptococcus pneumoniae Taiwan19F-14 hydroxyethylthiazole kinase YP_002742204.1 698806 D 487213 CDS YP_002742205.1 225860696 7686789 699590..700219 1 NC_012469.1 identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693; thiamine-phosphate pyrophosphorylase 700219 thiE1 7686789 thiE1 Streptococcus pneumoniae Taiwan19F-14 thiamine-phosphate pyrophosphorylase YP_002742205.1 699590 D 487213 CDS YP_002742206.1 225860697 7686252 700778..701338 1 NC_012469.1 cobalt ABC transporter permease 701338 7686252 SPT_0735 Streptococcus pneumoniae Taiwan19F-14 cobalt ABC transporter permease YP_002742206.1 700778 D 487213 CDS YP_002742207.1 225860698 7685540 701339..702724 1 NC_012469.1 identified by match to protein family HMM PF00005; cobalt ABC transporter ATP-binding protein 702724 7685540 SPT_0736 Streptococcus pneumoniae Taiwan19F-14 cobalt ABC transporter ATP-binding protein YP_002742207.1 701339 D 487213 CDS YP_002742208.1 225860699 7686315 702726..703376 1 NC_012469.1 hypothetical protein 703376 7686315 SPT_0737 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742208.1 702726 D 487213 CDS YP_002742209.1 225860700 7685829 703387..704079 1 NC_012469.1 identified by match to protein family HMM PF03070; tena/thi-4 family 704079 7685829 SPT_0738 Streptococcus pneumoniae Taiwan19F-14 tena/thi-4 family YP_002742209.1 703387 D 487213 CDS YP_002742210.1 225860701 7686515 704084..704608 1 NC_012469.1 identified by match to protein family HMM TIGR02359; ThiW protein 704608 thiW 7686515 thiW Streptococcus pneumoniae Taiwan19F-14 ThiW protein YP_002742210.1 704084 D 487213 CDS YP_002742211.1 225860702 7685749 704608..705411 1 NC_012469.1 identified by match to protein family HMM PF02110; hydroxyethylthiazole kinase 705411 7685749 SPT_0740 Streptococcus pneumoniae Taiwan19F-14 hydroxyethylthiazole kinase YP_002742211.1 704608 D 487213 CDS YP_002742212.1 225860703 7687268 705404..706036 1 NC_012469.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 706036 thiE 7687268 thiE Streptococcus pneumoniae Taiwan19F-14 thiamine-phosphate pyrophosphorylase YP_002742212.1 705404 D 487213 CDS YP_002742213.1 225860704 7686029 complement(706245..707036) 1 NC_012469.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 707036 thiD 7686029 thiD Streptococcus pneumoniae Taiwan19F-14 phosphomethylpyrimidine kinase YP_002742213.1 706245 R 487213 CDS YP_002742214.1 225860705 7687004 707402..707797 1 NC_012469.1 identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698; copper transport repressor, CopY/TcrY family 707797 7687004 SPT_0743 Streptococcus pneumoniae Taiwan19F-14 copper transport repressor, CopY/TcrY family YP_002742214.1 707402 D 487213 CDS YP_002742215.1 225860706 7686140 707808..708179 1 NC_012469.1 hypothetical protein 708179 7686140 SPT_0744 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742215.1 707808 D 487213 CDS YP_002742216.1 225860707 7686325 708189..710432 1 NC_012469.1 cation-transporting ATPase PacS 710432 7686325 SPT_0745 Streptococcus pneumoniae Taiwan19F-14 cation-transporting ATPase PacS YP_002742216.1 708189 D 487213 CDS YP_002742217.1 225860708 7687021 710639..712414 1 NC_012469.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720; pyruvate oxidase 712414 spxB 7687021 spxB Streptococcus pneumoniae Taiwan19F-14 pyruvate oxidase YP_002742217.1 710639 D 487213 CDS YP_002742218.1 225860709 7687397 712525..712872 1 NC_012469.1 identified by match to protein family HMM PF00903; glyoxalase family protein 712872 7687397 SPT_0747 Streptococcus pneumoniae Taiwan19F-14 glyoxalase family protein YP_002742218.1 712525 D 487213 CDS YP_002742219.1 225860710 7686168 complement(712989..713642) 1 NC_012469.1 transposase family protein 713642 7686168 SPT_0748 Streptococcus pneumoniae Taiwan19F-14 transposase family protein YP_002742219.1 712989 R 487213 CDS YP_002742220.1 225860711 7687065 complement(713530..713796) 1 NC_012469.1 transposase 713796 7687065 SPT_0749 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742220.1 713530 R 487213 CDS YP_002742221.1 225860712 7685294 complement(713793..714035) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 714035 7685294 SPT_0750 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742221.1 713793 R 487213 CDS YP_002742222.1 225860713 7686099 714100..714396 1 NC_012469.1 6-phospho-beta-glucosidase AscB 714396 7686099 SPT_0751 Streptococcus pneumoniae Taiwan19F-14 6-phospho-beta-glucosidase AscB YP_002742222.1 714100 D 487213 CDS YP_002742223.1 225860714 7685790 714517..715461 1 NC_012469.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase, class I 715461 manA 7685790 manA Streptococcus pneumoniae Taiwan19F-14 mannose-6-phosphate isomerase, class I YP_002742223.1 714517 D 487213 CDS YP_002742224.1 225860715 7687348 complement(715482..716813) 1 NC_012469.1 identified by match to protein family HMM PF00209; sodium-dependent transporter 716813 7687348 SPT_0753 Streptococcus pneumoniae Taiwan19F-14 sodium-dependent transporter YP_002742224.1 715482 R 487213 CDS YP_002742225.1 225860716 7685866 complement(718145..719320) 1 NC_012469.1 identified by match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein 719320 7685866 SPT_0756 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742225.1 718145 R 487213 CDS YP_002742226.1 225860717 7685312 complement(719379..720224) 1 NC_012469.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 720224 7685312 SPT_0757 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742226.1 719379 R 487213 CDS YP_002742227.1 225860718 7686285 720349..720906 1 NC_012469.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 720906 7686285 SPT_0758 Streptococcus pneumoniae Taiwan19F-14 TetR family transcriptional regulator YP_002742227.1 720349 D 487213 CDS YP_002742228.1 225860719 7687201 720925..721392 1 NC_012469.1 identified by match to protein family HMM PF00383; ComE operon protein 2 721392 7687201 SPT_0759 Streptococcus pneumoniae Taiwan19F-14 ComE operon protein 2 YP_002742228.1 720925 D 487213 CDS YP_002742229.1 225860720 7686392 721460..722110 1 NC_012469.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 722110 upp 7686392 upp Streptococcus pneumoniae Taiwan19F-14 uracil phosphoribosyltransferase YP_002742229.1 721460 D 487213 CDS YP_002742230.1 225860721 7686613 722284..722874 1 NC_012469.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 722874 clpP 7686613 clpP Streptococcus pneumoniae Taiwan19F-14 ATP-dependent Clp protease proteolytic subunit YP_002742230.1 722284 D 487213 CDS YP_002742231.1 225860722 7685764 722953..723201 1 NC_012469.1 hypothetical protein 723201 7685764 SPT_0762 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742231.1 722953 D 487213 CDS YP_002742232.1 225860723 7686144 723303..724463 1 NC_012469.1 identified by match to protein family HMM PF01094; ABC transporter substrate-binding protein - branched chain amino acid transport 724463 7686144 SPT_0763 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - branched chain amino acid transport YP_002742232.1 723303 D 487213 CDS YP_002742233.1 225860724 7686833 724731..725600 1 NC_012469.1 identified by match to protein family HMM PF02653; high-affinity branched-chain amino acid transport system permeaseprotein LivH (LIV-I protein H) 725600 7686833 SPT_0764 Streptococcus pneumoniae Taiwan19F-14 high-affinity branched-chain amino acid transport system permeaseprotein LivH (LIV-I protein H) YP_002742233.1 724731 D 487213 CDS YP_002742234.1 225860725 7686571 725604..726560 1 NC_012469.1 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 726560 7686571 SPT_0765 Streptococcus pneumoniae Taiwan19F-14 branched-chain amino acid ABC transporter permease YP_002742234.1 725604 D 487213 CDS YP_002742235.1 225860726 7687369 726560..727324 1 NC_012469.1 identified by match to protein family HMM PF00005; high-affinity branched-chain amino acid transport ATP-binding proteinlivG (LIV-I protein G) 727324 7687369 SPT_0766 Streptococcus pneumoniae Taiwan19F-14 high-affinity branched-chain amino acid transport ATP-binding proteinlivG (LIV-I protein G) YP_002742235.1 726560 D 487213 CDS YP_002742236.1 225860727 7685332 727324..728034 1 NC_012469.1 identified by match to protein family HMM PF00005; high-affinity branched-chain amino acid transport ATP-binding proteinlivF (LIV-I protein F) 728034 7685332 SPT_0767 Streptococcus pneumoniae Taiwan19F-14 high-affinity branched-chain amino acid transport ATP-binding proteinlivF (LIV-I protein F) YP_002742236.1 727324 D 487213 CDS YP_002742237.1 225860728 7685674 728448..729104 1 NC_012469.1 identified by match to protein family HMM PF00571; AcuB family protein 729104 7685674 SPT_0768 Streptococcus pneumoniae Taiwan19F-14 AcuB family protein YP_002742237.1 728448 D 487213 CDS YP_002742238.1 225860729 7686440 729318..730307 1 NC_012469.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 730307 prfB 7686440 prfB Streptococcus pneumoniae Taiwan19F-14 peptide chain release factor 2 YP_002742238.1 729318 D 487213 CDS YP_002742239.1 225860730 7686591 730325..731017 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673; cell division ATP-binding protein FtsE 731017 ftsE 7686591 ftsE Streptococcus pneumoniae Taiwan19F-14 cell division ATP-binding protein FtsE YP_002742239.1 730325 D 487213 CDS YP_002742240.1 225860731 7685683 731010..731936 1 NC_012469.1 cell division ABC transporter, permease protein FtsX 731936 7685683 SPT_0771 Streptococcus pneumoniae Taiwan19F-14 cell division ABC transporter, permease protein FtsX YP_002742240.1 731010 D 487213 CDS YP_002742241.1 225860732 7687038 732222..734402 1 NC_012469.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02003; pts system, iibc component 734402 7687038 SPT_0772 Streptococcus pneumoniae Taiwan19F-14 pts system, iibc component YP_002742241.1 732222 D 487213 CDS YP_002742242.1 225860733 7686006 734454..735269 1 NC_012469.1 identified by match to protein family HMM PF03372; metal-dependent hydrolase 735269 7686006 SPT_0773 Streptococcus pneumoniae Taiwan19F-14 metal-dependent hydrolase YP_002742242.1 734454 D 487213 CDS YP_002742243.1 225860734 7686161 735409..736752 1 NC_012469.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; superfamily II DNA and RNA helicase 736752 7686161 SPT_0774 Streptococcus pneumoniae Taiwan19F-14 superfamily II DNA and RNA helicase YP_002742243.1 735409 D 487213 CDS YP_002742244.1 225860735 7686243 737129..738319 1 NC_012469.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 738319 metK 7686243 metK Streptococcus pneumoniae Taiwan19F-14 S-adenosylmethionine synthetase YP_002742244.1 737129 D 487213 CDS YP_002742245.1 225860736 7686634 complement(738409..738573) 1 NC_012469.1 hypothetical protein 738573 7686634 SPT_0776 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742245.1 738409 R 487213 CDS YP_002742246.1 225860737 7686324 738872..739807 1 NC_012469.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 739807 7686324 SPT_0777 Streptococcus pneumoniae Taiwan19F-14 dihydroorotate dehydrogenase 1A YP_002742246.1 738872 D 487213 CDS YP_002742247.1 225860738 7687394 739841..740878 1 NC_012469.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 740878 holA 7687394 holA Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III subunit delta YP_002742247.1 739841 D 487213 CDS YP_002742248.1 225860739 7686877 741051..741656 1 NC_012469.1 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase [Mn] (General stress protein 24)(GSP24) 741656 7686877 SPT_0779 Streptococcus pneumoniae Taiwan19F-14 superoxide dismutase [Mn] (General stress protein 24)(GSP24) YP_002742248.1 741051 D 487213 CDS YP_002742249.1 225860740 7686154 741813..742343 1 NC_012469.1 identified by match to protein family HMM PF06265; transcriptional regulator 742343 7686154 SPT_0780 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator YP_002742249.1 741813 D 487213 CDS YP_002742250.1 225860741 7685919 742364..743266 1 NC_012469.1 identified by match to protein family HMM TIGR00048; radical SAM enzyme, Cfr family 743266 7685919 SPT_0781 Streptococcus pneumoniae Taiwan19F-14 radical SAM enzyme, Cfr family YP_002742250.1 742364 D 487213 CDS YP_002742251.1 225860742 7685271 743266..743748 1 NC_012469.1 identified by match to protein family HMM PF04892; VanZ family protein 743748 7685271 SPT_0782 Streptococcus pneumoniae Taiwan19F-14 VanZ family protein YP_002742251.1 743266 D 487213 CDS YP_002742252.1 225860743 7686150 743750..745291 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 745291 7686150 SPT_0783 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742252.1 743750 D 487213 CDS YP_002742253.1 225860744 7687158 complement(745347..746150) 1 NC_012469.1 identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase, cyclophilin-type 746150 7687158 SPT_0784 Streptococcus pneumoniae Taiwan19F-14 peptidyl-prolyl cis-trans isomerase, cyclophilin-type YP_002742253.1 745347 R 487213 CDS YP_002742254.1 225860745 7685469 complement(746234..746446) 1 NC_012469.1 hypothetical protein 746446 7685469 SPT_0785 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742254.1 746234 R 487213 CDS YP_002742255.1 225860746 7686086 complement(746925..747125) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 747125 7686086 SPT_0786 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742255.1 746925 R 487213 CDS YP_002742256.1 225860747 7686965 747304..747576 1 NC_012469.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 747576 rpsP 7686965 rpsP Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S16 YP_002742256.1 747304 D 487213 CDS YP_002742257.1 225860748 7687200 747596..747835 1 NC_012469.1 hypothetical protein 747835 7687200 SPT_0788 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742257.1 747596 D 487213 CDS YP_002742258.1 225860749 7686264 complement(748227..749573) 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 749573 7686264 SPT_0789 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742258.1 748227 R 487213 CDS YP_002742259.1 225860750 7687233 749858..750208 1 NC_012469.1 transposase family protein 750208 7687233 SPT_0792 Streptococcus pneumoniae Taiwan19F-14 transposase family protein YP_002742259.1 749858 D 487213 CDS YP_002742260.1 225860751 7686430 complement(752031..753008) 1 NC_012469.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; oxidoreductase 753008 7686430 SPT_0795 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase YP_002742260.1 752031 R 487213 CDS YP_002742261.1 225860752 7685943 753223..753600 1 NC_012469.1 hypothetical protein 753600 7685943 SPT_0796 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742261.1 753223 D 487213 CDS YP_002742262.1 225860753 7686623 753784..755226 1 NC_012469.1 identified by match to protein family HMM PF01522; peptidoglycan GlcNAc deacetylase 755226 7686623 SPT_0797 Streptococcus pneumoniae Taiwan19F-14 peptidoglycan GlcNAc deacetylase YP_002742262.1 753784 D 487213 CDS YP_002742263.1 225860754 7685679 755340..756182 1 NC_012469.1 identified by match to protein family HMM PF00248; 2,5-diketo-d-gluconic acid reductase a (2,5-dkgreductase a) (2,5-dkgr a) (25dkgr-a) (akr5c) 756182 7685679 SPT_0798 Streptococcus pneumoniae Taiwan19F-14 2,5-diketo-d-gluconic acid reductase a (2,5-dkgreductase a) (2,5-dkgr a) (25dkgr-a) (akr5c) YP_002742263.1 755340 D 487213 CDS YP_002742264.1 225860755 7687039 756455..757216 1 NC_012469.1 hypothetical protein 757216 7687039 SPT_0799 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742264.1 756455 D 487213 CDS YP_002742265.1 225860756 7686246 757409..758326 1 NC_012469.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 758326 glyQ 7686246 glyQ Streptococcus pneumoniae Taiwan19F-14 glycyl-tRNA synthetase subunit alpha YP_002742265.1 757409 D 487213 CDS YP_002742266.1 225860757 7686174 758586..760622 1 NC_012469.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 760622 glyS 7686174 glyS Streptococcus pneumoniae Taiwan19F-14 glycyl-tRNA synthetase subunit beta YP_002742266.1 758586 D 487213 CDS YP_002742267.1 225860758 7686458 760664..760921 1 NC_012469.1 identified by match to protein family HMM PF05979; hypothetical protein 760921 7686458 SPT_0802 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742267.1 760664 D 487213 CDS YP_002742268.1 225860759 7686406 complement(761038..762282) 1 NC_012469.1 identified by match to protein family HMM PF03358; NADPH-dependent fmn reductase domain protein 762282 7686406 SPT_0803 Streptococcus pneumoniae Taiwan19F-14 NADPH-dependent fmn reductase domain protein YP_002742268.1 761038 R 487213 CDS YP_002742269.1 225860760 7686506 complement(762301..762906) 1 NC_012469.1 NADPH-dependent fmn reductase domain protein 762906 7686506 SPT_0804 Streptococcus pneumoniae Taiwan19F-14 NADPH-dependent fmn reductase domain protein YP_002742269.1 762301 R 487213 CDS YP_002742270.1 225860761 7685698 complement(762966..763889) 1 NC_012469.1 identified by match to protein family HMM PF02424; thiamine biosynthesis lipoprotein 763889 7685698 SPT_0805 Streptococcus pneumoniae Taiwan19F-14 thiamine biosynthesis lipoprotein YP_002742270.1 762966 R 487213 CDS YP_002742271.1 225860762 7686061 764183..765562 1 NC_012469.1 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; NADH oxidase (noxase) 765562 7686061 SPT_0806 Streptococcus pneumoniae Taiwan19F-14 NADH oxidase (noxase) YP_002742271.1 764183 D 487213 CDS YP_002742272.1 225860763 7687069 765714..766589 1 NC_012469.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 766589 7687069 SPT_0807 Streptococcus pneumoniae Taiwan19F-14 pyridoxal biosynthesis lyase PdxS YP_002742272.1 765714 D 487213 CDS YP_002742273.1 225860764 7686460 766590..767171 1 NC_012469.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 767171 7686460 SPT_0808 Streptococcus pneumoniae Taiwan19F-14 glutamine amidotransferase subunit PdxT YP_002742273.1 766590 D 487213 CDS YP_002742274.1 225860765 7687167 complement(767192..767839) 1 NC_012469.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin-3 (Hemolysin III) (Hly-III) 767839 7687167 SPT_0809 Streptococcus pneumoniae Taiwan19F-14 hemolysin-3 (Hemolysin III) (Hly-III) YP_002742274.1 767192 R 487213 CDS YP_002742275.1 225860766 7686233 complement(767836..768282) 1 NC_012469.1 identified by match to protein family HMM PF08876; hypothetical protein 768282 7686233 SPT_0810 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742275.1 767836 R 487213 CDS YP_002742276.1 225860767 7686113 768417..768911 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 768911 7686113 SPT_0811 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742276.1 768417 D 487213 CDS YP_002742277.1 225860768 7687074 768911..769441 1 NC_012469.1 O6-methylguanine-DNA methyltransferase 769441 7687074 SPT_0812 Streptococcus pneumoniae Taiwan19F-14 O6-methylguanine-DNA methyltransferase YP_002742277.1 768911 D 487213 CDS YP_002742278.1 225860769 7685244 769435..769791 1 NC_012469.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; arsenate reductase 769791 7685244 SPT_0813 Streptococcus pneumoniae Taiwan19F-14 arsenate reductase YP_002742278.1 769435 D 487213 CDS YP_002742279.1 225860770 7686944 769949..770749 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; aspartate/glutamate ABC transporter permease 770749 7686944 SPT_0814 Streptococcus pneumoniae Taiwan19F-14 aspartate/glutamate ABC transporter permease YP_002742279.1 769949 D 487213 CDS YP_002742280.1 225860771 7687077 770749..771492 1 NC_012469.1 identified by match to protein family HMM PF00005; L-cystine import ATP-binding protein TcyN 771492 7687077 SPT_0815 Streptococcus pneumoniae Taiwan19F-14 L-cystine import ATP-binding protein TcyN YP_002742280.1 770749 D 487213 CDS YP_002742281.1 225860772 7686649 771570..771794 1 NC_012469.1 hypothetical protein 771794 7686649 SPT_0816 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742281.1 771570 D 487213 CDS YP_002742282.1 225860773 7685675 771860..772771 1 NC_012469.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin-disulfide reductase 772771 trxB 7685675 trxB Streptococcus pneumoniae Taiwan19F-14 thioredoxin-disulfide reductase YP_002742282.1 771860 D 487213 CDS YP_002742283.1 225860774 7686170 complement(772809..773537) 1 NC_012469.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; RNA methyltransferase, TrmH family, group 3 773537 7686170 SPT_0818 Streptococcus pneumoniae Taiwan19F-14 RNA methyltransferase, TrmH family, group 3 YP_002742283.1 772809 R 487213 CDS YP_002742284.1 225860775 7686098 complement(773582..774193) 1 NC_012469.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 774193 def 7686098 def Streptococcus pneumoniae Taiwan19F-14 peptide deformylase YP_002742284.1 773582 R 487213 CDS YP_002742285.1 225860776 7686352 complement(774517..774630) 1 NC_012469.1 hypothetical protein 774630 7686352 SPT_0820 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742285.1 774517 R 487213 CDS YP_002742286.1 225860777 7686903 775780..776607 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein 776607 7686903 SPT_0823 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742286.1 775780 D 487213 CDS YP_002742287.1 225860778 7687232 776609..777244 1 NC_012469.1 identified by match to protein family HMM PF00657; hypothetical protein 777244 7687232 SPT_0824 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742287.1 776609 D 487213 CDS YP_002742288.1 225860779 7686396 777328..778053 1 NC_012469.1 CppA protein 778053 7686396 SPT_0825 Streptococcus pneumoniae Taiwan19F-14 CppA protein YP_002742288.1 777328 D 487213 CDS YP_002742289.1 225860780 7686178 778050..778985 1 NC_012469.1 identified by match to protein family HMM PF00144; beta-lactamase 778985 7686178 SPT_0826 Streptococcus pneumoniae Taiwan19F-14 beta-lactamase YP_002742289.1 778050 D 487213 CDS YP_002742290.1 225860781 7685329 778994..779890 1 NC_012469.1 identified by match to protein family HMM PF00892; membrane protein 779890 7685329 SPT_0827 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002742290.1 778994 D 487213 CDS YP_002742291.1 225860782 7686389 complement(779933..780631) 1 NC_012469.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 780631 7686389 SPT_0828 Streptococcus pneumoniae Taiwan19F-14 GntR family transcriptional regulator YP_002742291.1 779933 R 487213 CDS YP_002742292.1 225860783 7685432 780773..782335 1 NC_012469.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 782335 guaA 7685432 guaA Streptococcus pneumoniae Taiwan19F-14 GMP synthase YP_002742292.1 780773 D 487213 CDS YP_002742293.1 225860784 7686284 784177..784323 1 NC_012469.1 hypothetical protein 784323 7686284 SPT_0833 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742293.1 784177 D 487213 CDS YP_002742294.1 225860785 7685435 complement(784445..785437) 1 NC_012469.1 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 785437 7685435 SPT_0834 Streptococcus pneumoniae Taiwan19F-14 AraC family transcriptional regulator YP_002742294.1 784445 R 487213 CDS YP_002742295.1 225860786 7685660 785597..787351 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein/permease 787351 7685660 SPT_0835 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein/permease YP_002742295.1 785597 D 487213 CDS YP_002742296.1 225860787 7685717 787335..789056 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 789056 7685717 SPT_0836 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742296.1 787335 D 487213 CDS YP_002742297.1 225860788 7687353 789067..789651 1 NC_012469.1 identified by match to protein family HMM TIGR02185; hypothetical protein 789651 7687353 SPT_0837 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742297.1 789067 D 487213 CDS YP_002742298.1 225860789 7685245 789651..790346 1 NC_012469.1 hypothetical protein 790346 7685245 SPT_0838 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742298.1 789651 D 487213 CDS YP_002742299.1 225860790 7685944 790334..791698 1 NC_012469.1 identified by match to protein family HMM PF00005; cobalt ABC transporter, ATPase component, CbiO 791698 7685944 SPT_0839 Streptococcus pneumoniae Taiwan19F-14 cobalt ABC transporter, ATPase component, CbiO YP_002742299.1 790334 D 487213 CDS YP_002742300.1 225860791 7686015 complement(792986..794176) 1 NC_012469.1 identified by match to protein family HMM PF01555; DNA modification methyltransferase M.XbaI 794176 7686015 SPT_0843 Streptococcus pneumoniae Taiwan19F-14 DNA modification methyltransferase M.XbaI YP_002742300.1 792986 R 487213 CDS YP_002742301.1 225860792 7686752 795354..796640 1 NC_012469.1 identified by match to protein family HMM PF01136; peptidase, U32 family protein 796640 7686752 SPT_0846 Streptococcus pneumoniae Taiwan19F-14 peptidase, U32 family protein YP_002742301.1 795354 D 487213 CDS YP_002742302.1 225860793 7685645 complement(796895..797044) 1 NC_012469.1 hypothetical protein 797044 7685645 SPT_0847 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742302.1 796895 R 487213 CDS YP_002742303.1 225860794 7687005 797229..797954 1 NC_012469.1 identified by match to protein family HMM PF01136; peptidase, U32 family 797954 7687005 SPT_0848 Streptococcus pneumoniae Taiwan19F-14 peptidase, U32 family YP_002742303.1 797229 D 487213 CDS YP_002742304.1 225860795 7686345 798459..799181 1 NC_012469.1 identified by match to protein family HMM PF00005; multidrug ABC transporter ATP-binding protein 799181 7686345 SPT_0849 Streptococcus pneumoniae Taiwan19F-14 multidrug ABC transporter ATP-binding protein YP_002742304.1 798459 D 487213 CDS YP_002742305.1 225860796 7686671 799197..799925 1 NC_012469.1 hypothetical protein 799925 7686671 SPT_0850 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742305.1 799197 D 487213 CDS YP_002742306.1 225860797 7686172 800311..800520 1 NC_012469.1 identified by match to protein family HMM PF01381; hypothetical protein 800520 7686172 SPT_0851 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742306.1 800311 D 487213 CDS YP_002742307.1 225860798 7685920 800510..800998 1 NC_012469.1 identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM PF03328; match to protein family HMM TIGR01064; hypothetical protein 800998 7685920 SPT_0852 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742307.1 800510 D 487213 CDS YP_002742308.1 225860799 7686755 801114..802574 1 NC_012469.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 802574 pncB 7686755 pncB Streptococcus pneumoniae Taiwan19F-14 nicotinate phosphoribosyltransferase YP_002742308.1 801114 D 487213 CDS YP_002742309.1 225860800 7686065 802571..803395 1 NC_012469.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 803395 nadE 7686065 nadE Streptococcus pneumoniae Taiwan19F-14 NAD synthetase YP_002742309.1 802571 D 487213 CDS YP_002742310.1 225860801 7686844 803745..804296 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 804296 7686844 SPT_0855 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742310.1 803745 D 487213 CDS YP_002742311.1 225860802 7686423 805758..806147 1 NC_012469.1 identified by match to protein family HMM PF01473; choline binding protein 806147 7686423 SPT_0856 Streptococcus pneumoniae Taiwan19F-14 choline binding protein YP_002742311.1 805758 D 487213 CDS YP_002742312.1 225860803 7685874 806371..807717 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 807717 7685874 SPT_0857 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742312.1 806371 D 487213 CDS YP_002742313.1 225860804 7685936 complement(808516..809544) 1 NC_012469.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 809544 queA 7685936 queA Streptococcus pneumoniae Taiwan19F-14 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002742313.1 808516 R 487213 CDS YP_002742314.1 225860805 7685472 809695..810402 1 NC_012469.1 identified by match to protein family HMM PF01182; glucosamine-6-phosphate deaminase (glucosamine-6-phosphate isomerase) (gnpda) (glcn6p deaminase) 810402 7685472 SPT_0859 Streptococcus pneumoniae Taiwan19F-14 glucosamine-6-phosphate deaminase (glucosamine-6-phosphate isomerase) (gnpda) (glcn6p deaminase) YP_002742314.1 809695 D 487213 CDS YP_002742315.1 225860806 7686278 810542..810718 1 NC_012469.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 810718 rpsU 7686278 rpsU Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S21 YP_002742315.1 810542 D 487213 CDS YP_002742316.1 225860807 7687231 810848..811783 1 NC_012469.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 811783 hprK 7687231 hprK Streptococcus pneumoniae Taiwan19F-14 HPr kinase/phosphorylase YP_002742316.1 810848 D 487213 CDS YP_002742317.1 225860808 7685539 811776..812564 1 NC_012469.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 812564 lgt 7685539 lgt Streptococcus pneumoniae Taiwan19F-14 prolipoprotein diacylglyceryl transferase YP_002742317.1 811776 D 487213 CDS YP_002742318.1 225860809 7686350 812565..812948 1 NC_012469.1 identified by match to protein family HMM PF06103; hypothetical protein 812948 7686350 SPT_0863 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742318.1 812565 D 487213 CDS YP_002742319.1 225860810 7686326 812964..813353 1 NC_012469.1 hypothetical protein 813353 7686326 SPT_0864 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742319.1 812964 D 487213 CDS YP_002742320.1 225860811 7685284 813437..814567 1 NC_012469.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 814567 7685284 SPT_0865 Streptococcus pneumoniae Taiwan19F-14 coproporphyrinogen III oxidase YP_002742320.1 813437 D 487213 CDS YP_002742321.1 225860812 7686221 814572..815309 1 NC_012469.1 identified by match to protein family HMM PF01643; acyl-ACP thioesterase 815309 7686221 SPT_0866 Streptococcus pneumoniae Taiwan19F-14 acyl-ACP thioesterase YP_002742321.1 814572 D 487213 CDS YP_002742322.1 225860813 7686632 815320..816093 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460; HAD-superfamily subfamily IIA hydrolase 816093 7686632 SPT_0867 Streptococcus pneumoniae Taiwan19F-14 HAD-superfamily subfamily IIA hydrolase YP_002742322.1 815320 D 487213 CDS YP_002742323.1 225860814 7686741 816083..816700 1 NC_012469.1 identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906; integral membrane protein 816700 7686741 SPT_0868 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002742323.1 816083 D 487213 CDS YP_002742324.1 225860815 7686521 816910..817311 1 NC_012469.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 817311 spxA 7686521 spxA Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator Spx YP_002742324.1 816910 D 487213 CDS YP_002742325.1 225860816 7685379 817311..817589 1 NC_012469.1 identified by match to protein family HMM PF05256; hypothetical protein 817589 7685379 SPT_0870 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742325.1 817311 D 487213 CDS YP_002742326.1 225860817 7685632 817579..818352 1 NC_012469.1 identified by match to protein family HMM PF00459; inositol monophosphatase family protein 818352 7685632 SPT_0871 Streptococcus pneumoniae Taiwan19F-14 inositol monophosphatase family protein YP_002742326.1 817579 D 487213 CDS YP_002742327.1 225860818 7686081 818353..819657 1 NC_012469.1 identified by match to protein family HMM PF01189; NOL1/NOP2/sun family protein 819657 7686081 SPT_0872 Streptococcus pneumoniae Taiwan19F-14 NOL1/NOP2/sun family protein YP_002742327.1 818353 D 487213 CDS YP_002742328.1 225860819 7686978 complement(819888..820001) 1 NC_012469.1 hypothetical protein 820001 7686978 SPT_0873 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742328.1 819888 R 487213 CDS YP_002742329.1 225860820 7685796 820231..821109 1 NC_012469.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate-binding protein PstS 1 (PBP 1) 821109 7685796 SPT_0874 Streptococcus pneumoniae Taiwan19F-14 phosphate-binding protein PstS 1 (PBP 1) YP_002742329.1 820231 D 487213 CDS YP_002742330.1 225860821 7687363 821109..822026 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 822026 pstC1 7687363 pstC1 Streptococcus pneumoniae Taiwan19F-14 phosphate ABC transporter permease YP_002742330.1 821109 D 487213 CDS YP_002742331.1 225860822 7686733 822016..822900 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 822900 pstA1 7686733 pstA1 Streptococcus pneumoniae Taiwan19F-14 phosphate ABC transporter permease YP_002742331.1 822016 D 487213 CDS YP_002742332.1 225860823 7685613 822911..823714 1 NC_012469.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 823714 pstB1 7685613 pstB1 Streptococcus pneumoniae Taiwan19F-14 phosphate transporter ATP-binding protein YP_002742332.1 822911 D 487213 CDS YP_002742333.1 225860824 7685307 823727..824485 1 NC_012469.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 824485 pstB2 7685307 pstB2 Streptococcus pneumoniae Taiwan19F-14 phosphate transporter ATP-binding protein YP_002742333.1 823727 D 487213 CDS YP_002742334.1 225860825 7687219 824497..825150 1 NC_012469.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 825150 phoU1 7687219 phoU1 Streptococcus pneumoniae Taiwan19F-14 phosphate transport system regulatory protein PhoU YP_002742334.1 824497 D 487213 CDS YP_002742335.1 225860826 7685657 825307..826122 1 NC_012469.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine-binding protein 826122 7685657 SPT_0880 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - glutamine-binding protein YP_002742335.1 825307 D 487213 CDS YP_002742336.1 225860827 7686596 complement(826142..827413) 1 NC_012469.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 827413 7686596 SPT_0881 Streptococcus pneumoniae Taiwan19F-14 GntR family transcriptional regulator YP_002742336.1 826142 R 487213 CDS YP_002742337.1 225860828 7686159 827555..828286 1 NC_012469.1 identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252; alpha-acetolactate decarboxylase 828286 7686159 SPT_0882 Streptococcus pneumoniae Taiwan19F-14 alpha-acetolactate decarboxylase YP_002742337.1 827555 D 487213 CDS YP_002742338.1 225860829 7686428 828296..829048 1 NC_012469.1 hypothetical protein 829048 7686428 SPT_0884 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742338.1 828296 D 487213 CDS YP_002742339.1 225860830 7687334 829160..830110 1 NC_012469.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 830110 murB 7687334 murB Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002742339.1 829160 D 487213 CDS YP_002742340.1 225860831 7687138 830169..831326 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; spermidine/putrescine import ATP-binding protein PotA 831326 7687138 SPT_0886 Streptococcus pneumoniae Taiwan19F-14 spermidine/putrescine import ATP-binding protein PotA YP_002742340.1 830169 D 487213 CDS YP_002742341.1 225860832 7686943 831307..832113 1 NC_012469.1 identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 832113 7686943 SPT_0887 Streptococcus pneumoniae Taiwan19F-14 spermidine/putrescine ABC transporter permease YP_002742341.1 831307 D 487213 CDS YP_002742342.1 225860833 7685404 832110..832883 1 NC_012469.1 identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 832883 7685404 SPT_0888 Streptococcus pneumoniae Taiwan19F-14 spermidine/putrescine ABC transporter permease YP_002742342.1 832110 D 487213 CDS YP_002742343.1 225860834 7685265 832880..833950 1 NC_012469.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein - spermidine/putrescine transport 833950 7685265 SPT_0889 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - spermidine/putrescine transport YP_002742343.1 832880 D 487213 CDS YP_002742344.1 225860835 7685310 834709..835194 1 NC_012469.1 identified by match to protein family HMM PF04525; hypothetical protein 835194 7685310 SPT_0890 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742344.1 834709 D 487213 CDS YP_002742345.1 225860836 7686141 835216..837834 1 NC_012469.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 837834 alaS 7686141 alaS Streptococcus pneumoniae Taiwan19F-14 alanyl-tRNA synthetase YP_002742345.1 835216 D 487213 CDS YP_002742346.1 225860837 7686694 complement(837924..839378) 1 NC_012469.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 839378 7686694 SPT_0892 Streptococcus pneumoniae Taiwan19F-14 cytoplasmic alpha-amylase YP_002742346.1 837924 R 487213 CDS YP_002742347.1 225860838 7687295 839557..840306 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 840306 7687295 SPT_0893 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742347.1 839557 D 487213 CDS YP_002742348.1 225860839 7686909 840287..841921 1 NC_012469.1 hypothetical protein 841921 7686909 SPT_0894 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742348.1 840287 D 487213 CDS YP_002742349.1 225860840 7686042 842606..843769 1 NC_012469.1 methyltransferase 843769 7686042 SPT_0895 Streptococcus pneumoniae Taiwan19F-14 methyltransferase YP_002742349.1 842606 D 487213 CDS YP_002742350.1 225860841 7686889 843766..844443 1 NC_012469.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 844443 aroD 7686889 aroD Streptococcus pneumoniae Taiwan19F-14 3-dehydroquinate dehydratase YP_002742350.1 843766 D 487213 CDS YP_002742351.1 225860842 7687115 844433..845287 1 NC_012469.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 845287 aroE 7687115 aroE Streptococcus pneumoniae Taiwan19F-14 shikimate 5-dehydrogenase YP_002742351.1 844433 D 487213 CDS YP_002742352.1 225860843 7685867 845306..846373 1 NC_012469.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 846373 aroB 7685867 aroB Streptococcus pneumoniae Taiwan19F-14 3-dehydroquinate synthase YP_002742352.1 845306 D 487213 CDS YP_002742353.1 225860844 7686138 846383..847549 1 NC_012469.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 847549 aroC 7686138 aroC Streptococcus pneumoniae Taiwan19F-14 chorismate synthase YP_002742353.1 846383 D 487213 CDS YP_002742354.1 225860845 7685255 847559..848662 1 NC_012469.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 848662 7685255 SPT_0900 Streptococcus pneumoniae Taiwan19F-14 prephenate dehydrogenase YP_002742354.1 847559 D 487213 CDS YP_002742355.1 225860846 7687171 848673..849011 1 NC_012469.1 identified by match to protein family HMM PF06133; hypothetical protein 849011 7687171 SPT_0901 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742355.1 848673 D 487213 CDS YP_002742356.1 225860847 7685626 849103..850386 1 NC_012469.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 850386 aroA 7685626 aroA Streptococcus pneumoniae Taiwan19F-14 3-phosphoshikimate 1-carboxyvinyltransferase YP_002742356.1 849103 D 487213 CDS YP_002742357.1 225860848 7685387 850379..850855 1 NC_012469.1 identified by match to protein family HMM PF01202; shikimate kinase 850855 aroK 7685387 aroK Streptococcus pneumoniae Taiwan19F-14 shikimate kinase YP_002742357.1 850379 D 487213 CDS YP_002742358.1 225860849 7687110 850852..851700 1 NC_012469.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 851700 7687110 SPT_0904 Streptococcus pneumoniae Taiwan19F-14 prephenate dehydratase YP_002742358.1 850852 D 487213 CDS YP_002742359.1 225860850 7686839 851697..852971 1 NC_012469.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator, LytR family 852971 7686839 SPT_0905 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, LytR family YP_002742359.1 851697 D 487213 CDS YP_002742360.1 225860851 7685681 853250..854095 1 NC_012469.1 identified by match to protein family HMM PF04991; LicD1 protein 854095 7685681 SPT_0906 Streptococcus pneumoniae Taiwan19F-14 LicD1 protein YP_002742360.1 853250 D 487213 CDS YP_002742361.1 225860852 7685771 854085..855188 1 NC_012469.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 855188 7685771 SPT_0907 Streptococcus pneumoniae Taiwan19F-14 glycosyl transferase, group 1 YP_002742361.1 854085 D 487213 CDS YP_002742362.1 225860853 7686919 855190..856176 1 NC_012469.1 identified by match to protein family HMM PF00535; glycosyl transferase, family 2 856176 7686919 SPT_0908 Streptococcus pneumoniae Taiwan19F-14 glycosyl transferase, family 2 YP_002742362.1 855190 D 487213 CDS YP_002742363.1 225860854 7685208 856192..857625 1 NC_012469.1 hypothetical protein 857625 7685208 SPT_0909 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742363.1 856192 D 487213 CDS YP_002742364.1 225860855 7685984 857654..858688 1 NC_012469.1 hypothetical protein 858688 7685984 SPT_0910 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742364.1 857654 D 487213 CDS YP_002742365.1 225860856 7685860 858888..859625 1 NC_012469.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 859625 7685860 SPT_0911 Streptococcus pneumoniae Taiwan19F-14 adaptor protein YP_002742365.1 858888 D 487213 CDS YP_002742366.1 225860857 7686644 861065..861934 1 NC_012469.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 861934 thrB 7686644 thrB Streptococcus pneumoniae Taiwan19F-14 homoserine kinase YP_002742366.1 861065 D 487213 CDS YP_002742367.1 225860858 7685898 861950..862246 1 NC_012469.1 hypothetical protein 862246 7685898 SPT_0915 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742367.1 861950 D 487213 CDS YP_002742368.1 225860859 7687337 862275..863213 1 NC_012469.1 identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 863213 7687337 SPT_0916 Streptococcus pneumoniae Taiwan19F-14 peptide methionine sulfoxide reductase MsrA/msrB YP_002742368.1 862275 D 487213 CDS YP_002742369.1 225860860 7687175 863271..864995 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 864995 7687175 SPT_0917 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein/permease YP_002742369.1 863271 D 487213 CDS YP_002742370.1 225860861 7686448 864997..866745 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 866745 7686448 SPT_0918 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein/permease YP_002742370.1 864997 D 487213 CDS YP_002742371.1 225860862 7686920 867002..868261 1 NC_012469.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; chlorohydrolase 868261 7686920 SPT_0919 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742371.1 867002 D 487213 CDS YP_002742372.1 225860863 7685259 868511..869011 1 NC_012469.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 869011 rplJ 7685259 rplJ Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L10 YP_002742372.1 868511 D 487213 CDS YP_002742373.1 225860864 7686945 869087..869455 1 NC_012469.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 869455 rplL 7686945 rplL Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L7/L12 YP_002742373.1 869087 D 487213 CDS YP_002742374.1 225860865 7686094 869702..873280 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 873280 7686094 SPT_0922 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742374.1 869702 D 487213 CDS YP_002742375.1 225860866 7687351 complement(873569..874915) 1 NC_012469.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 874915 7687351 SPT_0923 Streptococcus pneumoniae Taiwan19F-14 glutamate dehydrogenase YP_002742375.1 873569 R 487213 CDS YP_002742376.1 225860867 7686023 875752..875937 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 875937 7686023 SPT_0924 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742376.1 875752 D 487213 CDS YP_002742377.1 225860868 7685913 875969..876478 1 NC_012469.1 transposase family protein 876478 7685913 SPT_0925 Streptococcus pneumoniae Taiwan19F-14 transposase family protein YP_002742377.1 875969 D 487213 CDS YP_002742378.1 225860869 7687325 876475..876693 1 NC_012469.1 high-affinity Fe2+/Pb2+ permease 876693 7687325 SPT_0926 Streptococcus pneumoniae Taiwan19F-14 high-affinity Fe2+/Pb2+ permease YP_002742378.1 876475 D 487213 CDS YP_002742379.1 225860870 7687082 complement(876751..876993) 1 NC_012469.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 876993 rpmE2 7687082 rpmE2 Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L31 type B YP_002742379.1 876751 R 487213 CDS YP_002742380.1 225860871 7687017 complement(877089..878024) 1 NC_012469.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein 878024 7687017 SPT_0928 Streptococcus pneumoniae Taiwan19F-14 DHH subfamily 1 protein YP_002742380.1 877089 R 487213 CDS YP_002742381.1 225860872 7687263 878128..878571 1 NC_012469.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 878571 7687263 SPT_0929 Streptococcus pneumoniae Taiwan19F-14 flavodoxin YP_002742381.1 878128 D 487213 CDS YP_002742382.1 225860873 7686927 878687..878953 1 NC_012469.1 identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805; hypothetical protein 878953 7686927 SPT_0930 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742382.1 878687 D 487213 CDS YP_002742383.1 225860874 7686034 878950..879324 1 NC_012469.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 879324 7686034 SPT_0931 Streptococcus pneumoniae Taiwan19F-14 camphor resistance protein CrcB YP_002742383.1 878950 D 487213 CDS YP_002742384.1 225860875 7686922 879318..879647 1 NC_012469.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 879647 7686922 SPT_0932 Streptococcus pneumoniae Taiwan19F-14 camphor resistance protein CrcB YP_002742384.1 879318 D 487213 CDS YP_002742385.1 225860876 7687213 879766..880113 1 NC_012469.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 880113 rplS 7687213 rplS Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L19 YP_002742385.1 879766 D 487213 CDS YP_002742386.1 225860877 7686580 complement(880398..881396) 1 NC_012469.1 identified by match to protein family HMM PF02037; SAP domain protein 881396 7686580 SPT_0935 Streptococcus pneumoniae Taiwan19F-14 SAP domain protein YP_002742386.1 880398 R 487213 CDS YP_002742387.1 225860878 7685242 complement(881439..882245) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YidA 882245 7685242 SPT_0936 Streptococcus pneumoniae Taiwan19F-14 phosphatase YidA YP_002742387.1 881439 R 487213 CDS YP_002742388.1 225860879 7686892 complement(882258..883562) 1 NC_012469.1 identified by match to protein family HMM PF01966; HD superfamily phosphohydrolase 883562 7686892 SPT_0937 Streptococcus pneumoniae Taiwan19F-14 HD superfamily phosphohydrolase YP_002742388.1 882258 R 487213 CDS YP_002742389.1 225860880 7685993 883634..884011 1 NC_012469.1 identified by match to protein family HMM PF09148; hypothetical protein 884011 7685993 SPT_0938 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742389.1 883634 D 487213 CDS YP_002742390.1 225860881 7685360 884102..884434 1 NC_012469.1 identified by match to protein family HMM PF04297; match to protein family HMM PF04967; match to protein family HMM PF08281; putative DNA-binding protein 884434 7685360 SPT_0939 Streptococcus pneumoniae Taiwan19F-14 putative DNA-binding protein YP_002742390.1 884102 D 487213 CDS YP_002742391.1 225860882 7686382 884446..886017 1 NC_012469.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 886017 ffh 7686382 ffh Streptococcus pneumoniae Taiwan19F-14 signal recognition particle protein YP_002742391.1 884446 D 487213 CDS YP_002742392.1 225860883 7685424 complement(886212..887495) 1 NC_012469.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease (Uracil transporter) 887495 7685424 SPT_0941 Streptococcus pneumoniae Taiwan19F-14 uracil permease (Uracil transporter) YP_002742392.1 886212 R 487213 CDS YP_002742393.1 225860884 7685438 complement(887749..888462) 1 NC_012469.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 888462 gidB 7685438 gidB Streptococcus pneumoniae Taiwan19F-14 16S rRNA methyltransferase GidB YP_002742393.1 887749 R 487213 CDS YP_002742394.1 225860885 7685877 888556..889116 1 NC_012469.1 identified by match to protein family HMM PF04011; cytoplasmic membrane protein 889116 7685877 SPT_0943 Streptococcus pneumoniae Taiwan19F-14 cytoplasmic membrane protein YP_002742394.1 888556 D 487213 CDS YP_002742395.1 225860886 7685948 889118..890017 1 NC_012469.1 putative metalloprotease; heat shock protein HtpX 890017 7685948 SPT_0944 Streptococcus pneumoniae Taiwan19F-14 heat shock protein HtpX YP_002742395.1 889118 D 487213 CDS YP_002742396.1 225860887 7687060 complement(890061..891587) 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 891587 7687060 SPT_0945 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742396.1 890061 R 487213 CDS YP_002742397.1 225860888 7685214 complement(892036..892224) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 892224 7685214 SPT_0946 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742397.1 892036 R 487213 CDS YP_002742398.1 225860889 7686711 892346..892888 1 NC_012469.1 identified by match to protein family HMM PF02620; hypothetical protein 892888 7686711 SPT_0947 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742398.1 892346 D 487213 CDS YP_002742399.1 225860890 7685707 892888..893517 1 NC_012469.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 893517 nth 7685707 nth Streptococcus pneumoniae Taiwan19F-14 endonuclease III YP_002742399.1 892888 D 487213 CDS YP_002742400.1 225860891 7685521 893728..894249 1 NC_012469.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 894249 7685521 SPT_0949 Streptococcus pneumoniae Taiwan19F-14 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_002742400.1 893728 D 487213 CDS YP_002742401.1 225860892 7685431 894268..895191 1 NC_012469.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 895191 pyrB 7685431 pyrB Streptococcus pneumoniae Taiwan19F-14 aspartate carbamoyltransferase catalytic subunit YP_002742401.1 894268 D 487213 CDS YP_002742402.1 225860893 7686433 895241..896320 1 NC_012469.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 896320 carA 7686433 carA Streptococcus pneumoniae Taiwan19F-14 carbamoyl phosphate synthase small subunit YP_002742402.1 895241 D 487213 CDS YP_002742403.1 225860894 7686673 896633..899809 1 NC_012469.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 899809 carB 7686673 carB Streptococcus pneumoniae Taiwan19F-14 carbamoyl phosphate synthase large subunit YP_002742403.1 896633 D 487213 CDS YP_002742404.1 225860895 7686801 complement(900084..900893) 1 NC_012469.1 identified by match to protein family HMM PF04991; LicD Protein 900893 7686801 SPT_0953 Streptococcus pneumoniae Taiwan19F-14 LicD Protein YP_002742404.1 900084 R 487213 CDS YP_002742405.1 225860896 7687045 complement(900895..901698) 1 NC_012469.1 required for phosphorylcholine incorporation in teichoic and lipoteichoic acids; identified by match to protein family HMM PF04991; phosphotransferase 901698 7687045 SPT_0954 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase YP_002742405.1 900895 R 487213 CDS YP_002742406.1 225860897 7687114 complement(901708..903195) 1 NC_012469.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide biosynthesis protein 903195 7687114 SPT_0956 Streptococcus pneumoniae Taiwan19F-14 polysaccharide biosynthesis protein YP_002742406.1 901708 R 487213 CDS YP_002742407.1 225860898 7685828 903531..904238 1 NC_012469.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 904238 ispD 7685828 ispD Streptococcus pneumoniae Taiwan19F-14 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002742407.1 903531 D 487213 CDS YP_002742408.1 225860899 7687265 904243..905265 1 NC_012469.1 identified by match to protein family HMM PF08240; xylitol dehydrogenase 905265 7687265 SPT_0958 Streptococcus pneumoniae Taiwan19F-14 xylitol dehydrogenase YP_002742408.1 904243 D 487213 CDS YP_002742409.1 225860900 7685767 905282..906151 1 NC_012469.1 identified by match to protein family HMM PF01633; match to protein family HMM PF01636; choline kinase 906151 7685767 SPT_0959 Streptococcus pneumoniae Taiwan19F-14 choline kinase YP_002742409.1 905282 D 487213 CDS YP_002742410.1 225860901 7686379 906141..907019 1 NC_012469.1 identified by match to protein family HMM PF00892; LPS epitope expression regulatory protein 907019 7686379 SPT_0960 Streptococcus pneumoniae Taiwan19F-14 LPS epitope expression regulatory protein YP_002742410.1 906141 D 487213 CDS YP_002742411.1 225860902 7685411 907031..907720 1 NC_012469.1 identified by match to protein family HMM PF00483; LPS epitope expression regulatory protein 907720 7685411 SPT_0961 Streptococcus pneumoniae Taiwan19F-14 LPS epitope expression regulatory protein YP_002742411.1 907031 D 487213 CDS YP_002742412.1 225860903 7686261 907816..908664 1 NC_012469.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 908664 dprA 7686261 dprA Streptococcus pneumoniae Taiwan19F-14 DNA protecting protein DprA YP_002742412.1 907816 D 487213 CDS YP_002742413.1 225860904 7687342 complement(908847..908969) 1 NC_012469.1 chlorohydrolase 908969 7687342 SPT_0963 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742413.1 908847 R 487213 CDS YP_002742414.1 225860905 7687279 909546..910589 1 NC_012469.1 identified by match to protein family HMM PF04087; hypothetical protein 910589 7687279 SPT_0964 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742414.1 909546 D 487213 CDS YP_002742415.1 225860906 7687311 910756..912843 1 NC_012469.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 912843 topA 7687311 topA Streptococcus pneumoniae Taiwan19F-14 DNA topoisomerase I YP_002742415.1 910756 D 487213 CDS YP_002742416.1 225860907 7686507 912949..913308 1 NC_012469.1 identified by match to protein family HMM PF04304; hypothetical protein 913308 7686507 SPT_0966 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742416.1 912949 D 487213 CDS YP_002742417.1 225860908 7686222 913401..914033 1 NC_012469.1 identified by match to protein family HMM PF03932; copper sensitivity 914033 7686222 SPT_0967 Streptococcus pneumoniae Taiwan19F-14 copper sensitivity YP_002742417.1 913401 D 487213 CDS YP_002742418.1 225860909 7685344 914077..914733 1 NC_012469.1 identified by match to protein family HMM PF04237; hypothetical protein 914733 7685344 SPT_0968 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742418.1 914077 D 487213 CDS YP_002742419.1 225860910 7685229 915858..916895 1 NC_012469.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 916895 leuB 7685229 leuB Streptococcus pneumoniae Taiwan19F-14 3-isopropylmalate dehydrogenase YP_002742419.1 915858 D 487213 CDS YP_002742420.1 225860911 7685780 916892..917161 1 NC_012469.1 identified by match to protein family HMM PF06961; hypothetical protein 917161 7685780 SPT_0972 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742420.1 916892 D 487213 CDS YP_002742421.1 225860912 7687361 917165..917524 1 NC_012469.1 hypothetical protein 917524 7687361 SPT_0973 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742421.1 917165 D 487213 CDS YP_002742422.1 225860913 7685335 917743..917886 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 917886 7685335 SPT_0974 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742422.1 917743 D 487213 CDS YP_002742423.1 225860914 7686179 917892..918158 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 918158 7686179 SPT_0975 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742423.1 917892 D 487213 CDS YP_002742424.1 225860915 7685765 918139..918309 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 918309 7685765 SPT_0976 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742424.1 918139 D 487213 CDS YP_002742425.1 225860916 7685868 918475..920406 1 NC_012469.1 hypothetical protein 920406 7685868 SPT_0977 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742425.1 918475 D 487213 CDS YP_002742426.1 225860917 7686930 920390..921709 1 NC_012469.1 hypothetical protein 921709 7686930 SPT_0978 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742426.1 920390 D 487213 CDS YP_002742427.1 225860918 7687204 921884..922870 1 NC_012469.1 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306; guanosine 5'-monophosphate oxidoreductase 922870 guaC 7687204 guaC Streptococcus pneumoniae Taiwan19F-14 guanosine 5'-monophosphate oxidoreductase YP_002742427.1 921884 D 487213 CDS YP_002742428.1 225860919 7685605 923188..923886 1 NC_012469.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 923886 rnc 7685605 rnc Streptococcus pneumoniae Taiwan19F-14 ribonuclease III YP_002742428.1 923188 D 487213 CDS YP_002742429.1 225860920 7685468 923877..927416 1 NC_012469.1 identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168; chromosome segregation protein SMC 927416 smc 7685468 smc Streptococcus pneumoniae Taiwan19F-14 chromosome segregation protein SMC YP_002742429.1 923877 D 487213 CDS YP_002742430.1 225860921 7687091 927413..928207 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 928207 7687091 SPT_0983 Streptococcus pneumoniae Taiwan19F-14 Cof family protein YP_002742430.1 927413 D 487213 CDS YP_002742431.1 225860922 7687052 928207..929025 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 929025 7687052 SPT_0984 Streptococcus pneumoniae Taiwan19F-14 Cof family protein YP_002742431.1 928207 D 487213 CDS YP_002742432.1 225860923 7685642 929029..930318 1 NC_012469.1 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; cell division protein FtsY 930318 7685642 SPT_0985 Streptococcus pneumoniae Taiwan19F-14 cell division protein FtsY YP_002742432.1 929029 D 487213 CDS YP_002742433.1 225860924 7686823 complement(930362..931849) 1 NC_012469.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 931849 zwf 7686823 zwf Streptococcus pneumoniae Taiwan19F-14 glucose-6-phosphate 1-dehydrogenase YP_002742433.1 930362 R 487213 CDS YP_002742434.1 225860925 7687116 complement(931998..932738) 1 NC_012469.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 932738 7687116 SPT_0987 Streptococcus pneumoniae Taiwan19F-14 glutamine transport ATP-binding protein GlnQ YP_002742434.1 931998 R 487213 CDS YP_002742435.1 225860926 7686628 complement(932738..934903) 1 NC_012469.1 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein 934903 7686628 SPT_0988 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter permease/substrate-binding protein YP_002742435.1 932738 R 487213 CDS YP_002742436.1 225860927 7686361 935073..936026 1 NC_012469.1 identified by match to protein family HMM PF02517; caax amino protease family 936026 7686361 SPT_0989 Streptococcus pneumoniae Taiwan19F-14 caax amino protease family YP_002742436.1 935073 D 487213 CDS YP_002742437.1 225860928 7686977 936103..938091 1 NC_012469.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 938091 uvrB 7686977 uvrB Streptococcus pneumoniae Taiwan19F-14 excinuclease ABC subunit B YP_002742437.1 936103 D 487213 CDS YP_002742438.1 225860929 7685961 938101..938664 1 NC_012469.1 acetyltransferase, gnat family 938664 7685961 SPT_0991 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742438.1 938101 D 487213 CDS YP_002742439.1 225860930 7686327 938630..939118 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 939118 7686327 SPT_0992 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742439.1 938630 D 487213 CDS YP_002742440.1 225860931 7686530 939191..939658 1 NC_012469.1 identified by match to protein family HMM PF00293; NTP pyrophosphohydrolase including oxidative damage repair enzymes 939658 7686530 SPT_0994 Streptococcus pneumoniae Taiwan19F-14 NTP pyrophosphohydrolase including oxidative damage repair enzymes YP_002742440.1 939191 D 487213 CDS YP_002742441.1 225860932 7686862 complement(939655..940170) 1 NC_012469.1 identified by match to protein family HMM PF02829; match to protein family HMM PF08279; transcriptional regulator, biotin repressor family 940170 7686862 SPT_0993 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, biotin repressor family YP_002742441.1 939655 R 487213 CDS YP_002742442.1 225860933 7686219 complement(940182..940709) 1 NC_012469.1 hypothetical protein 940709 7686219 SPT_0995 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742442.1 940182 R 487213 CDS YP_002742443.1 225860934 7686845 complement(941005..941568) 1 NC_012469.1 integral membrane protein 941568 7686845 SPT_0996 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002742443.1 941005 R 487213 CDS YP_002742444.1 225860935 7686797 complement(941552..942103) 1 NC_012469.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 942103 coaC 7686797 coaC Streptococcus pneumoniae Taiwan19F-14 phosphopantothenoylcysteine decarboxylase YP_002742444.1 941552 R 487213 CDS YP_002742445.1 225860936 7685885 complement(942115..942804) 1 NC_012469.1 identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114; phosphopantothenate--cysteine ligase 942804 coaB 7685885 coaB Streptococcus pneumoniae Taiwan19F-14 phosphopantothenate--cysteine ligase YP_002742445.1 942115 R 487213 CDS YP_002742446.1 225860937 7685206 943034..944704 1 NC_012469.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 944704 fhs 7685206 fhs Streptococcus pneumoniae Taiwan19F-14 formate--tetrahydrofolate ligase YP_002742446.1 943034 D 487213 CDS YP_002742447.1 225860938 7685956 945033..946208 1 NC_012469.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 946208 mutY 7685956 mutY Streptococcus pneumoniae Taiwan19F-14 A/G-specific adenine glycosylase YP_002742447.1 945033 D 487213 CDS YP_002742448.1 225860939 7685629 946263..946967 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 946967 7685629 SPT_1001 Streptococcus pneumoniae Taiwan19F-14 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_002742448.1 946263 D 487213 CDS YP_002742449.1 225860940 7685736 946960..948309 1 NC_012469.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensor protein YycG 948309 7685736 SPT_1002 Streptococcus pneumoniae Taiwan19F-14 sensor protein YycG YP_002742449.1 946960 D 487213 CDS YP_002742450.1 225860941 7685857 948311..949120 1 NC_012469.1 identified by match to protein family HMM PF00753; VicX protein 949120 7685857 SPT_1003 Streptococcus pneumoniae Taiwan19F-14 VicX protein YP_002742450.1 948311 D 487213 CDS YP_002742451.1 225860942 7687276 949211..949453 1 NC_012469.1 hypothetical protein 949453 7687276 SPT_1004 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742451.1 949211 D 487213 CDS YP_002742452.1 225860943 7685883 949455..949709 1 NC_012469.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; cytotoxic translational repressor of toxin-antitoxin stability system 949709 7685883 SPT_1005 Streptococcus pneumoniae Taiwan19F-14 cytotoxic translational repressor of toxin-antitoxin stability system YP_002742452.1 949455 D 487213 CDS YP_002742453.1 225860944 7685417 949756..950529 1 NC_012469.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885; potassium/ion channel protein 950529 7685417 SPT_1006 Streptococcus pneumoniae Taiwan19F-14 potassium/ion channel protein YP_002742453.1 949756 D 487213 CDS YP_002742454.1 225860945 7686469 complement(950845..952191) 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 952191 7686469 SPT_1007 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742454.1 950845 R 487213 CDS YP_002742455.1 225860946 7686761 complement(952500..953486) 1 NC_012469.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 953486 ldh 7686761 ldh Streptococcus pneumoniae Taiwan19F-14 L-lactate dehydrogenase YP_002742455.1 952500 R 487213 CDS YP_002742456.1 225860947 7686721 953680..956148 1 NC_012469.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 956148 gyrA 7686721 gyrA Streptococcus pneumoniae Taiwan19F-14 DNA gyrase subunit A YP_002742456.1 953680 D 487213 CDS YP_002742457.1 225860948 7687068 956148..956891 1 NC_012469.1 identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase 956891 7687068 SPT_1011 Streptococcus pneumoniae Taiwan19F-14 sortase YP_002742457.1 956148 D 487213 CDS YP_002742458.1 225860949 7686205 957135..957932 1 NC_012469.1 identified by match to protein family HMM PF01226; formate-nitrate transporter 957932 7686205 SPT_1012 Streptococcus pneumoniae Taiwan19F-14 formate-nitrate transporter YP_002742458.1 957135 D 487213 CDS YP_002742459.1 225860950 7686513 959435..960709 1 NC_012469.1 hypothetical protein 960709 7686513 SPT_1015 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742459.1 959435 D 487213 CDS YP_002742460.1 225860951 7687196 960719..961597 1 NC_012469.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 961597 truB 7687196 truB Streptococcus pneumoniae Taiwan19F-14 tRNA pseudouridine synthase B YP_002742460.1 960719 D 487213 CDS YP_002742461.1 225860952 7686929 961838..962179 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 962179 7686929 SPT_1017 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742461.1 961838 D 487213 CDS YP_002742462.1 225860953 7686055 962244..962882 1 NC_012469.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 962882 udk 7686055 udk Streptococcus pneumoniae Taiwan19F-14 uridine kinase YP_002742462.1 962244 D 487213 CDS YP_002742463.1 225860954 7685491 963010..964350 1 NC_012469.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 964350 xseA 7685491 xseA Streptococcus pneumoniae Taiwan19F-14 exodeoxyribonuclease VII large subunit YP_002742463.1 963010 D 487213 CDS YP_002742464.1 225860955 7686010 964328..964540 1 NC_012469.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 964540 7686010 SPT_1020 Streptococcus pneumoniae Taiwan19F-14 exodeoxyribonuclease VII small subunit YP_002742464.1 964328 D 487213 CDS YP_002742465.1 225860956 7686031 964537..965412 1 NC_012469.1 identified by match to protein family HMM PF00348; geranyltranstransferase (Farnesyl-diphosphate synthase)(FPP synthase) 965412 7686031 SPT_1021 Streptococcus pneumoniae Taiwan19F-14 geranyltranstransferase (Farnesyl-diphosphate synthase)(FPP synthase) YP_002742465.1 964537 D 487213 CDS YP_002742466.1 225860957 7685267 965405..966220 1 NC_012469.1 identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 966220 tylA 7685267 tylA Streptococcus pneumoniae Taiwan19F-14 hemolysin A YP_002742466.1 965405 D 487213 CDS YP_002742467.1 225860958 7686008 966213..966644 1 NC_012469.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; transcriptional regulator of arginine metabolism expression 966644 7686008 SPT_1023 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator of arginine metabolism expression YP_002742467.1 966213 D 487213 CDS YP_002742468.1 225860959 7685732 966651..968318 1 NC_012469.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein RecN 968318 recN 7685732 recN Streptococcus pneumoniae Taiwan19F-14 DNA repair protein RecN YP_002742468.1 966651 D 487213 CDS YP_002742469.1 225860960 7686204 968320..969048 1 NC_012469.1 identified by match to protein family HMM PF00149; serine/threonine protein phosphatase 969048 7686204 SPT_1025 Streptococcus pneumoniae Taiwan19F-14 serine/threonine protein phosphatase YP_002742469.1 968320 D 487213 CDS YP_002742470.1 225860961 7686739 969127..970950 1 NC_012469.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 970950 lepA 7686739 lepA Streptococcus pneumoniae Taiwan19F-14 GTP-binding protein LepA YP_002742470.1 969127 D 487213 CDS YP_002742471.1 225860962 7686836 complement(971031..971183) 1 NC_012469.1 chlorohydrolase 971183 7686836 SPT_1027 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742471.1 971031 R 487213 CDS YP_002742472.1 225860963 7686778 971363..971839 1 NC_012469.1 identified by match to protein family HMM PF00359; phosphotransferase system sugar-specific EII component 971839 7686778 SPT_1028 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002742472.1 971363 D 487213 CDS YP_002742473.1 225860964 7686788 971877..972179 1 NC_012469.1 PTS system, galactose-specific IIB component 972179 7686788 SPT_1029 Streptococcus pneumoniae Taiwan19F-14 PTS system, galactose-specific IIB component YP_002742473.1 971877 D 487213 CDS YP_002742474.1 225860965 7685234 972523..972990 1 NC_012469.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 972990 7685234 SPT_1031 Streptococcus pneumoniae Taiwan19F-14 transposase (IS4 family) YP_002742474.1 972523 D 487213 CDS YP_002742475.1 225860966 7685400 973027..973503 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 973503 7685400 SPT_1032 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742475.1 973027 D 487213 CDS YP_002742476.1 225860967 7685628 973660..974085 1 NC_012469.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 974085 lacA 7685628 lacA Streptococcus pneumoniae Taiwan19F-14 galactose-6-phosphate isomerase subunit LacA YP_002742476.1 973660 D 487213 CDS YP_002742477.1 225860968 7686601 974116..974631 1 NC_012469.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 974631 lacB 7686601 lacB Streptococcus pneumoniae Taiwan19F-14 galactose-6-phosphate isomerase subunit LacB YP_002742477.1 974116 D 487213 CDS YP_002742478.1 225860969 7685228 974642..975571 1 NC_012469.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 975571 lacC 7685228 lacC Streptococcus pneumoniae Taiwan19F-14 tagatose-6-phosphate kinase YP_002742478.1 974642 D 487213 CDS YP_002742479.1 225860970 7686698 975573..976553 1 NC_012469.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 976553 lacD 7686698 lacD Streptococcus pneumoniae Taiwan19F-14 tagatose 1,6-diphosphate aldolase YP_002742479.1 975573 D 487213 CDS YP_002742480.1 225860971 7686858 976786..977622 1 NC_012469.1 identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LacT 977622 7686858 SPT_1037 Streptococcus pneumoniae Taiwan19F-14 transcription antiterminator LacT YP_002742480.1 976786 D 487213 CDS YP_002742481.1 225860972 7685461 977658..977975 1 NC_012469.1 identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823; lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) 977975 7685461 SPT_1038 Streptococcus pneumoniae Taiwan19F-14 lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) YP_002742481.1 977658 D 487213 CDS YP_002742482.1 225860973 7685881 977975..979666 1 NC_012469.1 pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) 979666 7685881 SPT_1039 Streptococcus pneumoniae Taiwan19F-14 pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) YP_002742482.1 977975 D 487213 CDS YP_002742483.1 225860974 7686658 979881..981287 1 NC_012469.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 981287 lacG2 7686658 lacG2 Streptococcus pneumoniae Taiwan19F-14 6-phospho-beta-galactosidase YP_002742483.1 979881 D 487213 CDS YP_002742484.1 225860975 7687323 981408..981587 1 NC_012469.1 hypothetical protein 981587 7687323 SPT_1041 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742484.1 981408 D 487213 CDS YP_002742485.1 225860976 7686466 complement(981866..982627) 1 NC_012469.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; lactose phosphotransferase system repressor 982627 7686466 SPT_1042 Streptococcus pneumoniae Taiwan19F-14 lactose phosphotransferase system repressor YP_002742485.1 981866 R 487213 CDS YP_002742486.1 225860977 7685416 complement(982809..983771) 1 NC_012469.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 983771 nrdF 7685416 nrdF Streptococcus pneumoniae Taiwan19F-14 ribonucleotide-diphosphate reductase subunit beta YP_002742486.1 982809 R 487213 CDS YP_002742487.1 225860978 7686273 complement(983959..986118) 1 NC_012469.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 986118 7686273 SPT_1044 Streptococcus pneumoniae Taiwan19F-14 ribonucleotide-diphosphate reductase subunit alpha YP_002742487.1 983959 R 487213 CDS YP_002742488.1 225860979 7685256 complement(986199..986417) 1 NC_012469.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194; glutaredoxin 986417 7685256 SPT_1045 Streptococcus pneumoniae Taiwan19F-14 glutaredoxin YP_002742488.1 986199 R 487213 CDS YP_002742489.1 225860980 7686444 986768..987031 1 NC_012469.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 987031 7686444 SPT_1046 Streptococcus pneumoniae Taiwan19F-14 phosphocarrier protein HPr YP_002742489.1 986768 D 487213 CDS YP_002742490.1 225860981 7686518 987037..988770 1 NC_012469.1 identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 988770 ptsP 7686518 ptsP Streptococcus pneumoniae Taiwan19F-14 phosphoenolpyruvate-protein phosphotransferase YP_002742490.1 987037 D 487213 CDS YP_002742491.1 225860982 7686612 complement(988789..988902) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 988902 7686612 SPT_1048 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742491.1 988789 R 487213 CDS YP_002742492.1 225860983 7685983 989023..991581 1 NC_012469.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 991581 7685983 SPT_1049 Streptococcus pneumoniae Taiwan19F-14 pneumococcal histidine triad protein B YP_002742492.1 989023 D 487213 CDS YP_002742493.1 225860984 7686846 991791..994910 1 NC_012469.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein E 994910 7686846 SPT_1050 Streptococcus pneumoniae Taiwan19F-14 pneumococcal histidine triad protein E YP_002742493.1 991791 D 487213 CDS YP_002742494.1 225860985 7685753 997214..997783 1 NC_012469.1 identified by match to protein family HMM PF04270; pneumococcal histidine triad protein E 997783 7685753 SPT_1053 Streptococcus pneumoniae Taiwan19F-14 pneumococcal histidine triad protein E YP_002742494.1 997214 D 487213 CDS YP_002742495.1 225860986 7687186 998078..998707 1 NC_012469.1 hypothetical protein 998707 7687186 SPT_1054 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742495.1 998078 D 487213 CDS YP_002742496.1 225860987 7687067 complement(998743..999966) 1 NC_012469.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 999966 pepT 7687067 pepT Streptococcus pneumoniae Taiwan19F-14 peptidase T YP_002742496.1 998743 R 487213 CDS YP_002742497.1 225860988 7685309 1000325..1000828 1 NC_012469.1 collagen adhesion protein 1000828 7685309 SPT_1056 Streptococcus pneumoniae Taiwan19F-14 collagen adhesion protein YP_002742497.1 1000325 D 487213 CDS YP_002742498.1 225860989 7686781 1001150..1002910 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1002910 7686781 SPT_1057 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742498.1 1001150 D 487213 CDS YP_002742499.1 225860990 7687137 1002910..1003461 1 NC_012469.1 identified by match to protein family HMM TIGR02227; signal peptidase I 1003461 lepB2 7687137 lepB2 Streptococcus pneumoniae Taiwan19F-14 signal peptidase I YP_002742499.1 1002910 D 487213 CDS YP_002742500.1 225860991 7686587 1003461..1004702 1 NC_012469.1 hypothetical protein 1004702 7686587 SPT_1059 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742500.1 1003461 D 487213 CDS YP_002742501.1 225860992 7685755 1004720..1005718 1 NC_012469.1 identified by match to protein family HMM PF07170; match to protein family HMM TIGR03064; sortase, SrtB family 1005718 srtB 7685755 srtB Streptococcus pneumoniae Taiwan19F-14 sortase, SrtB family YP_002742501.1 1004720 D 487213 CDS YP_002742502.1 225860993 7686033 1005959..1006594 1 NC_012469.1 identified by match to protein family HMM PF07170; surface protein cell wall anchor, sortase_B family 1006594 7686033 SPT_1061 Streptococcus pneumoniae Taiwan19F-14 surface protein cell wall anchor, sortase_B family YP_002742502.1 1005959 D 487213 CDS YP_002742503.1 225860994 7686838 1006697..1007791 1 NC_012469.1 identified by match to protein family HMM PF00762; match to protein family HMM TIGR00109; ferrochelatase 1007791 hemH 7686838 hemH Streptococcus pneumoniae Taiwan19F-14 ferrochelatase YP_002742503.1 1006697 D 487213 CDS YP_002742504.1 225860995 7686561 complement(1007833..1008210) 1 NC_012469.1 identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220; large conductance mechanosensitive channel protein 1008210 mscL 7686561 mscL Streptococcus pneumoniae Taiwan19F-14 large conductance mechanosensitive channel protein YP_002742504.1 1007833 R 487213 CDS YP_002742505.1 225860996 7687168 complement(1008292..1008723) 1 NC_012469.1 identified by match to protein family HMM PF04138; MesH protein 1008723 7687168 SPT_1064 Streptococcus pneumoniae Taiwan19F-14 MesH protein YP_002742505.1 1008292 R 487213 CDS YP_002742506.1 225860997 7686685 1008846..1009355 1 NC_012469.1 identified by match to protein family HMM PF06177; citrulline cluster-linked protein 1009355 7686685 SPT_1065 Streptococcus pneumoniae Taiwan19F-14 citrulline cluster-linked protein YP_002742506.1 1008846 D 487213 CDS YP_002742507.1 225860998 7685570 1009870..1010946 1 NC_012469.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1010946 asd 7685570 asd Streptococcus pneumoniae Taiwan19F-14 aspartate-semialdehyde dehydrogenase YP_002742507.1 1009870 D 487213 CDS YP_002742508.1 225860999 7686948 1011002..1011937 1 NC_012469.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1011937 dapA 7686948 dapA Streptococcus pneumoniae Taiwan19F-14 dihydrodipicolinate synthase YP_002742508.1 1011002 D 487213 CDS YP_002742509.1 225861000 7687390 complement(1011984..1013357) 1 NC_012469.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1013357 trmE 7687390 trmE Streptococcus pneumoniae Taiwan19F-14 tRNA modification GTPase TrmE YP_002742509.1 1011984 R 487213 CDS YP_002742510.1 225861001 7686567 complement(1013493..1013675) 1 NC_012469.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1013675 7686567 SPT_1070 Streptococcus pneumoniae Taiwan19F-14 4-oxalocrotonate tautomerase YP_002742510.1 1013493 R 487213 CDS YP_002742511.1 225861002 7685854 1013799..1014389 1 NC_012469.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1014389 tdk 7685854 tdk Streptococcus pneumoniae Taiwan19F-14 thymidine kinase YP_002742511.1 1013799 D 487213 CDS YP_002742512.1 225861003 7685985 1014386..1015465 1 NC_012469.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1015465 prfA 7685985 prfA Streptococcus pneumoniae Taiwan19F-14 peptide chain release factor 1 YP_002742512.1 1014386 D 487213 CDS YP_002742513.1 225861004 7685873 1015465..1016304 1 NC_012469.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387; protein-(glutamine-N5) methyltransferase, release factor-specific 1016304 hemK 7685873 hemK Streptococcus pneumoniae Taiwan19F-14 protein-(glutamine-N5) methyltransferase, release factor-specific YP_002742513.1 1015465 D 487213 CDS YP_002742514.1 225861005 7685247 1016288..1016890 1 NC_012469.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 1016890 7685247 SPT_1074 Streptococcus pneumoniae Taiwan19F-14 Sua5/YciO/YrdC/YwlC family protein YP_002742514.1 1016288 D 487213 CDS YP_002742515.1 225861006 7687019 1016892..1017323 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 1017323 7687019 SPT_1075 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family protein YP_002742515.1 1016892 D 487213 CDS YP_002742516.1 225861007 7687250 1017385..1018641 1 NC_012469.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1018641 glyA 7687250 glyA Streptococcus pneumoniae Taiwan19F-14 serine hydroxymethyltransferase YP_002742516.1 1017385 D 487213 CDS YP_002742517.1 225861008 7687059 1018649..1019623 1 NC_012469.1 hypothetical protein 1019623 7687059 SPT_1077 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742517.1 1018649 D 487213 CDS YP_002742518.1 225861009 7687081 1019623..1020237 1 NC_012469.1 pneumococcal vaccine antigen A 1020237 7687081 SPT_1078 Streptococcus pneumoniae Taiwan19F-14 pneumococcal vaccine antigen A YP_002742518.1 1019623 D 487213 CDS YP_002742519.1 225861010 7686667 1020311..1021285 1 NC_012469.1 identified by match to protein family HMM PF06207; hypothetical protein 1021285 7686667 SPT_1079 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742519.1 1020311 D 487213 CDS YP_002742520.1 225861011 7687031 1021359..1022990 1 NC_012469.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 1022990 rumA1 7687031 rumA1 Streptococcus pneumoniae Taiwan19F-14 23S rRNA (uracil-5-)-methyltransferase RumA YP_002742520.1 1021359 D 487213 CDS YP_002742521.1 225861012 7685655 1023728..1023946 1 NC_012469.1 hypothetical protein 1023946 7685655 SPT_1081 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742521.1 1023728 D 487213 CDS YP_002742522.1 225861013 7686592 1024339..1025364 1 NC_012469.1 identified by match to protein family HMM PF01497; ABC transporter substrate-binding protein - iron transport 1025364 7686592 SPT_1082 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - iron transport YP_002742522.1 1024339 D 487213 CDS YP_002742523.1 225861014 7686434 1025354..1026361 1 NC_012469.1 identified by match to protein family HMM PF01032; iron-compound ABC transporter, permease protein 1026361 7686434 SPT_1083 Streptococcus pneumoniae Taiwan19F-14 iron-compound ABC transporter, permease protein YP_002742523.1 1025354 D 487213 CDS YP_002742524.1 225861015 7686166 1026361..1027368 1 NC_012469.1 identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 1027368 7686166 SPT_1084 Streptococcus pneumoniae Taiwan19F-14 Fe3+ ABC transporter permease YP_002742524.1 1026361 D 487213 CDS YP_002742525.1 225861016 7686245 1027368..1028162 1 NC_012469.1 identified by match to protein family HMM PF00005; ferric enterobactin transport ATP-binding protein FepC 1028162 7686245 SPT_1085 Streptococcus pneumoniae Taiwan19F-14 ferric enterobactin transport ATP-binding protein FepC YP_002742525.1 1027368 D 487213 CDS YP_002742526.1 225861017 7686525 1028850..1029164 1 NC_012469.1 hypothetical protein 1029164 7686525 SPT_1086 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742526.1 1028850 D 487213 CDS YP_002742527.1 225861018 7686195 1029478..1031118 1 NC_012469.1 identified by match to protein family HMM PF03389; MobA/MobL family protein 1031118 7686195 SPT_1087 Streptococcus pneumoniae Taiwan19F-14 MobA/MobL family protein YP_002742527.1 1029478 D 487213 CDS YP_002742528.1 225861019 7686626 1031192..1031365 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1031365 7686626 SPT_1088 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742528.1 1031192 D 487213 CDS YP_002742529.1 225861020 7685641 1033259..1033792 1 NC_012469.1 hypothetical protein 1033792 7685641 SPT_1091 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742529.1 1033259 D 487213 CDS YP_002742530.1 225861021 7687085 1033919..1034641 1 NC_012469.1 identified by match to protein family HMM TIGR01714; putative phage-associated protein 1034641 7687085 SPT_1092 Streptococcus pneumoniae Taiwan19F-14 putative phage-associated protein YP_002742530.1 1033919 D 487213 CDS YP_002742531.1 225861022 7687008 1035325..1035486 1 NC_012469.1 hypothetical protein 1035486 7687008 SPT_1093 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742531.1 1035325 D 487213 CDS YP_002742532.1 225861023 7685220 1037525..1038091 1 NC_012469.1 hypothetical protein 1038091 7685220 SPT_1096 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742532.1 1037525 D 487213 CDS YP_002742533.1 225861024 7685827 1038412..1038600 1 NC_012469.1 hypothetical protein 1038600 7685827 SPT_1097 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742533.1 1038412 D 487213 CDS YP_002742534.1 225861025 7687310 1038662..1039420 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1039420 7687310 SPT_1098 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742534.1 1038662 D 487213 CDS YP_002742535.1 225861026 7686703 1039478..1040332 1 NC_012469.1 identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase superfamily 1040332 7686703 SPT_1099 Streptococcus pneumoniae Taiwan19F-14 ADP-ribosylglycohydrolase superfamily YP_002742535.1 1039478 D 487213 CDS YP_002742536.1 225861027 7685237 1040444..1041328 1 NC_012469.1 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147; hypothetical protein 1041328 7685237 SPT_1100 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742536.1 1040444 D 487213 CDS YP_002742537.1 225861028 7686884 1043505..1043807 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1043807 7686884 SPT_1104 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742537.1 1043505 D 487213 CDS YP_002742538.1 225861029 7685616 1043863..1044291 1 NC_012469.1 identified by match to protein family HMM PF00583; aminoglycoside 6'-N-acetyltransferase 1044291 7685616 SPT_1105 Streptococcus pneumoniae Taiwan19F-14 aminoglycoside 6'-N-acetyltransferase YP_002742538.1 1043863 D 487213 CDS YP_002742539.1 225861030 7686467 1044388..1044645 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1044645 7686467 SPT_1106 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742539.1 1044388 D 487213 CDS YP_002742540.1 225861031 7686786 1044674..1044958 1 NC_012469.1 hypothetical ABC transporter ATP-binding protein 1044958 7686786 SPT_1107 Streptococcus pneumoniae Taiwan19F-14 hypothetical ABC transporter ATP-binding protein YP_002742540.1 1044674 D 487213 CDS YP_002742541.1 225861032 7686569 1045592..1045786 1 NC_012469.1 transposase 1045786 7686569 SPT_1109 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742541.1 1045592 D 487213 CDS YP_002742542.1 225861033 7685479 1046050..1047279 1 NC_012469.1 identified by match to protein family HMM PF01098; cell division protein FtsW 1047279 7685479 SPT_1110 Streptococcus pneumoniae Taiwan19F-14 cell division protein FtsW YP_002742542.1 1046050 D 487213 CDS YP_002742543.1 225861034 7685939 1047299..1049995 1 NC_012469.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1049995 ppc 7685939 ppc Streptococcus pneumoniae Taiwan19F-14 phosphoenolpyruvate carboxylase YP_002742543.1 1047299 D 487213 CDS YP_002742544.1 225861035 7687120 1050408..1051412 1 NC_012469.1 identified by match to protein family HMM PF04392; ABC transporter substrate-binding protein 1051412 7687120 SPT_1112 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002742544.1 1050408 D 487213 CDS YP_002742545.1 225861036 7686869 1051481..1052347 1 NC_012469.1 identified by match to protein family HMM PF02653; ABC transporter 1052347 7686869 SPT_1113 Streptococcus pneumoniae Taiwan19F-14 ABC transporter YP_002742545.1 1051481 D 487213 CDS YP_002742546.1 225861037 7685703 1052344..1053102 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1053102 7685703 SPT_1114 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742546.1 1052344 D 487213 CDS YP_002742547.1 225861038 7686421 1053192..1054952 1 NC_012469.1 synthesizes RNA primers at the replication forks; DNA primase 1054952 dnaG 7686421 dnaG Streptococcus pneumoniae Taiwan19F-14 DNA primase YP_002742547.1 1053192 D 487213 CDS YP_002742548.1 225861039 7687229 1054955..1056064 1 NC_012469.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1056064 7687229 SPT_1116 Streptococcus pneumoniae Taiwan19F-14 RNA polymerase sigma factor RpoD YP_002742548.1 1054955 D 487213 CDS YP_002742549.1 225861040 7685833 1056078..1056407 1 NC_012469.1 identified by match to protein family HMM PF01883; N-6 Adenine-specific DNA methylase YitW 1056407 7685833 SPT_1117 Streptococcus pneumoniae Taiwan19F-14 N-6 Adenine-specific DNA methylase YitW YP_002742549.1 1056078 D 487213 CDS YP_002742550.1 225861041 7686135 1056522..1057565 1 NC_012469.1 identified by match to protein family HMM PF00534; glycosyl transferase CpoA 1057565 7686135 SPT_1118 Streptococcus pneumoniae Taiwan19F-14 glycosyl transferase CpoA YP_002742550.1 1056522 D 487213 CDS YP_002742551.1 225861042 7685325 1057581..1058906 1 NC_012469.1 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 1058906 7685325 SPT_1119 Streptococcus pneumoniae Taiwan19F-14 glycosyl transferase, group 1 YP_002742551.1 1057581 D 487213 CDS YP_002742552.1 225861043 7687372 1058937..1059113 1 NC_012469.1 identified by match to protein family HMM PF04024; hypothetical protein 1059113 7687372 SPT_1120 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742552.1 1058937 D 487213 CDS YP_002742553.1 225861044 7686054 1059172..1059306 1 NC_012469.1 hypothetical protein 1059306 7686054 SPT_1121 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742553.1 1059172 D 487213 CDS YP_002742554.1 225861045 7686933 1059376..1060680 1 NC_012469.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1060680 obgE 7686933 obgE Streptococcus pneumoniae Taiwan19F-14 GTPase ObgE YP_002742554.1 1059376 D 487213 CDS YP_002742555.1 225861046 7686866 1060690..1060848 1 NC_012469.1 hypothetical protein 1060848 7686866 SPT_1123 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742555.1 1060690 D 487213 CDS YP_002742556.1 225861047 7686935 1063402..1064661 1 NC_012469.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1064661 7686935 SPT_1127 Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002742556.1 1063402 D 487213 CDS YP_002742557.1 225861048 7686040 1064677..1065228 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 1065228 7686040 SPT_1128 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family protein YP_002742557.1 1064677 D 487213 CDS YP_002742558.1 225861049 7686270 1065221..1066498 1 NC_012469.1 identified by match to protein family HMM PF00571; match to protein family HMM PF07085; match to protein family HMM PF08279; cytosolic protein containing multiple CBS domains 1066498 7686270 SPT_1129 Streptococcus pneumoniae Taiwan19F-14 cytosolic protein containing multiple CBS domains YP_002742558.1 1065221 D 487213 CDS YP_002742559.1 225861050 7687225 1066514..1067374 1 NC_012469.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1067374 map 7687225 map Streptococcus pneumoniae Taiwan19F-14 methionine aminopeptidase YP_002742559.1 1066514 D 487213 CDS YP_002742560.1 225861051 7687371 1067473..1068153 1 NC_012469.1 mobile genetic element 1068153 7687371 SPT_1131 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002742560.1 1067473 D 487213 CDS YP_002742561.1 225861052 7686328 1068170..1068559 1 NC_012469.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 1068559 7686328 SPT_1132 Streptococcus pneumoniae Taiwan19F-14 transposase (IS4 family) YP_002742561.1 1068170 D 487213 CDS YP_002742562.1 225861053 7685627 1068751..1071042 1 NC_012469.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073; ATP-dependent DNA helicase PcrA 1071042 pcrA 7685627 pcrA Streptococcus pneumoniae Taiwan19F-14 ATP-dependent DNA helicase PcrA YP_002742562.1 1068751 D 487213 CDS YP_002742563.1 225861054 7685934 1071085..1071765 1 NC_012469.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1071765 radC 7685934 radC Streptococcus pneumoniae Taiwan19F-14 DNA repair protein RadC YP_002742563.1 1071085 D 487213 CDS YP_002742564.1 225861055 7686446 complement(1071762..1072451) 1 NC_012469.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase, class I 1072451 7686446 SPT_1134 Streptococcus pneumoniae Taiwan19F-14 glutamine amidotransferase, class I YP_002742564.1 1071762 R 487213 CDS YP_002742565.1 225861056 7686985 complement(1072469..1073110) 1 NC_012469.1 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1073110 7686985 SPT_1136 Streptococcus pneumoniae Taiwan19F-14 redox-sensing transcriptional repressor Rex YP_002742565.1 1072469 R 487213 CDS YP_002742566.1 225861057 7687383 complement(1073193..1073336) 1 NC_012469.1 hypothetical protein 1073336 7687383 SPT_1137 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742566.1 1073193 R 487213 CDS YP_002742567.1 225861058 7685738 complement(1073416..1073763) 1 NC_012469.1 identified by match to protein family HMM PF08866; hypothetical protein 1073763 7685738 SPT_1138 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742567.1 1073416 R 487213 CDS YP_002742568.1 225861059 7685917 complement(1073768..1074883) 1 NC_012469.1 identified by match to protein family HMM PF00266; cysteine desulfurase 1074883 7685917 SPT_1139 Streptococcus pneumoniae Taiwan19F-14 cysteine desulfurase YP_002742568.1 1073768 R 487213 CDS YP_002742569.1 225861060 7685507 complement(1074893..1075852) 1 NC_012469.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1075852 7685507 SPT_1140 Streptococcus pneumoniae Taiwan19F-14 ribose-phosphate pyrophosphokinase YP_002742569.1 1074893 R 487213 CDS YP_002742570.1 225861061 7686318 complement(1075965..1076534) 1 NC_012469.1 identified by match to protein family HMM PF01928; adenylate cyclase 1076534 7686318 SPT_1141 Streptococcus pneumoniae Taiwan19F-14 adenylate cyclase YP_002742570.1 1075965 R 487213 CDS YP_002742571.1 225861062 7687184 1076662..1077333 1 NC_012469.1 identified by match to protein family HMM PF04607; GTP pyrophosphokinase 1077333 7687184 SPT_1142 Streptococcus pneumoniae Taiwan19F-14 GTP pyrophosphokinase YP_002742571.1 1076662 D 487213 CDS YP_002742572.1 225861063 7685762 1077317..1078135 1 NC_012469.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1078135 ppnK 7685762 ppnK Streptococcus pneumoniae Taiwan19F-14 inorganic polyphosphate/ATP-NAD kinase YP_002742572.1 1077317 D 487213 CDS YP_002742573.1 225861064 7687288 1078132..1079028 1 NC_012469.1 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase, RluD subfamily 1079028 7687288 SPT_1144 Streptococcus pneumoniae Taiwan19F-14 ribosomal large subunit pseudouridine synthase, RluD subfamily YP_002742573.1 1078132 D 487213 CDS YP_002742574.1 225861065 7685383 1079072..1080046 1 NC_012469.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1080046 eutD 7685383 eutD Streptococcus pneumoniae Taiwan19F-14 phosphotransacetylase YP_002742574.1 1079072 D 487213 CDS YP_002742575.1 225861066 7686256 complement(1081939..1082238) 1 NC_012469.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 1082238 7686256 SPT_1149 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742575.1 1081939 R 487213 CDS YP_002742576.1 225861067 7687153 1082640..1083338 1 NC_012469.1 identified by match to protein family HMM PF06912; hypothetical protein 1083338 7687153 SPT_1150 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742576.1 1082640 D 487213 CDS YP_002742577.1 225861068 7685895 1083526..1083840 1 NC_012469.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1083840 rplU 7685895 rplU Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L21 YP_002742577.1 1083526 D 487213 CDS YP_002742578.1 225861069 7686519 1083856..1084200 1 NC_012469.1 identified by match to protein family HMM PF04327; hypothetical protein 1084200 7686519 SPT_1152 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742578.1 1083856 D 487213 CDS YP_002742579.1 225861070 7687117 1084217..1084510 1 NC_012469.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1084510 rpmA 7687117 rpmA Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L27 YP_002742579.1 1084217 D 487213 CDS YP_002742580.1 225861071 7686894 complement(1084750..1084920) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1084920 7686894 SPT_1154 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742580.1 1084750 R 487213 CDS YP_002742581.1 225861072 7686696 complement(1084892..1085020) 1 NC_012469.1 hypothetical protein 1085020 7686696 SPT_1155 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742581.1 1084892 R 487213 CDS YP_002742582.1 225861073 7686384 1085358..1086275 1 NC_012469.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1086275 ribF 7686384 ribF Streptococcus pneumoniae Taiwan19F-14 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002742582.1 1085358 D 487213 CDS YP_002742583.1 225861074 7687147 complement(1086368..1087216) 1 NC_012469.1 identified by match to protein family HMM PF02588; hypothetical protein 1087216 7687147 SPT_1157 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742583.1 1086368 R 487213 CDS YP_002742584.1 225861075 7686899 1087358..1088197 1 NC_012469.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 1088197 7686899 SPT_1158 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742584.1 1087358 D 487213 CDS YP_002742585.1 225861076 7686173 1088304..1088579 1 NC_012469.1 identified by match to protein family HMM PF00216; DNA-binding protein HU 1 (DNA-binding protein II) (HB) 1088579 7686173 SPT_1159 Streptococcus pneumoniae Taiwan19F-14 DNA-binding protein HU 1 (DNA-binding protein II) (HB) YP_002742585.1 1088304 D 487213 CDS YP_002742586.1 225861077 7686208 1089006..1090907 1 NC_012469.1 identified by match to protein family HMM PF00005; ATPase component of ABC transporter with duplicated ATPase domains 1090907 7686208 SPT_1160 Streptococcus pneumoniae Taiwan19F-14 ATPase component of ABC transporter with duplicated ATPase domains YP_002742586.1 1089006 D 487213 CDS YP_002742587.1 225861078 7686501 1090910..1091773 1 NC_012469.1 identified by match to protein family HMM TIGR01716; transcriptional regulator 1091773 7686501 SPT_1161 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator YP_002742587.1 1090910 D 487213 CDS YP_002742588.1 225861079 7686319 1091853..1093031 1 NC_012469.1 identified by match to protein family HMM PF07690; macrolide ABC transporter permease 1093031 7686319 SPT_1162 Streptococcus pneumoniae Taiwan19F-14 macrolide ABC transporter permease YP_002742588.1 1091853 D 487213 CDS YP_002742589.1 225861080 7685448 1093124..1095082 1 NC_012469.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1095082 ligA 7685448 ligA Streptococcus pneumoniae Taiwan19F-14 NAD-dependent DNA ligase LigA YP_002742589.1 1093124 D 487213 CDS YP_002742590.1 225861081 7685924 1095194..1097473 1 NC_012469.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; pullulanase, type I 1097473 pulA 7685924 pulA Streptococcus pneumoniae Taiwan19F-14 pullulanase, type I YP_002742590.1 1095194 D 487213 CDS YP_002742591.1 225861082 7686495 1098017..1099441 1 NC_012469.1 identified by match to protein family HMM PF00171; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1099441 7686495 SPT_1165 Streptococcus pneumoniae Taiwan19F-14 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase YP_002742591.1 1098017 D 487213 CDS YP_002742592.1 225861083 7686266 1099925..1101853 1 NC_012469.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1101853 glgB 7686266 glgB Streptococcus pneumoniae Taiwan19F-14 glycogen branching enzyme YP_002742592.1 1099925 D 487213 CDS YP_002742593.1 225861084 7685399 1101843..1102985 1 NC_012469.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1102985 glgC 7685399 glgC Streptococcus pneumoniae Taiwan19F-14 glucose-1-phosphate adenylyltransferase YP_002742593.1 1101843 D 487213 CDS YP_002742594.1 225861085 7686075 1102975..1104114 1 NC_012469.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092; glucose-1-phosphate adenylyltransferase, GlgD subunit 1104114 glgD 7686075 glgD Streptococcus pneumoniae Taiwan19F-14 glucose-1-phosphate adenylyltransferase, GlgD subunit YP_002742594.1 1102975 D 487213 CDS YP_002742595.1 225861086 7686743 1104111..1105544 1 NC_012469.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1105544 glgA 7686743 glgA Streptococcus pneumoniae Taiwan19F-14 glycogen synthase YP_002742595.1 1104111 D 487213 CDS YP_002742596.1 225861087 7685900 1106257..1107372 1 NC_012469.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 1107372 7685900 SPT_1172 Streptococcus pneumoniae Taiwan19F-14 glycerate kinase YP_002742596.1 1106257 D 487213 CDS YP_002742597.1 225861088 7686875 complement(1107369..1107815) 1 NC_012469.1 identified by match to protein family HMM PF07997; hypothetical protein 1107815 7686875 SPT_1171 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742597.1 1107369 R 487213 CDS YP_002742598.1 225861089 7686663 1107979..1109283 1 NC_012469.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1109283 eno 7686663 eno Streptococcus pneumoniae Taiwan19F-14 phosphopyruvate hydratase YP_002742598.1 1107979 D 487213 CDS YP_002742599.1 225861090 7686693 complement(1110970..1111221) 1 NC_012469.1 transposase 1111221 7686693 SPT_1176 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742599.1 1110970 R 487213 CDS YP_002742600.1 225861091 7685444 complement(1111400..1111729) 1 NC_012469.1 identified by match to protein family HMM PF01710; transposase 1111729 7685444 SPT_1177 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742600.1 1111400 R 487213 CDS YP_002742601.1 225861092 7686373 1112231..1115530 1 NC_012469.1 identified by match to protein family HMM TIGR02774; ATP-dependent nuclease subunit B 1115530 rexB 7686373 rexB Streptococcus pneumoniae Taiwan19F-14 ATP-dependent nuclease subunit B YP_002742601.1 1112231 D 487213 CDS YP_002742602.1 225861093 7686343 1115527..1119177 1 NC_012469.1 identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785; recombination helicase AddA 1119177 addA 7686343 addA Streptococcus pneumoniae Taiwan19F-14 recombination helicase AddA YP_002742602.1 1115527 D 487213 CDS YP_002742603.1 225861094 7686730 1119392..1120570 1 NC_012469.1 hypothetical protein 1120570 7686730 SPT_1180 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742603.1 1119392 D 487213 CDS YP_002742604.1 225861095 7685636 1120779..1126793 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; immunoglobulin A1 protease 1126793 7685636 SPT_1181 Streptococcus pneumoniae Taiwan19F-14 immunoglobulin A1 protease YP_002742604.1 1120779 D 487213 CDS YP_002742605.1 225861096 7686562 1127241..1128092 1 NC_012469.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1128092 rbgA 7686562 rbgA Streptococcus pneumoniae Taiwan19F-14 ribosomal biogenesis GTPase YP_002742605.1 1127241 D 487213 CDS YP_002742606.1 225861097 7686111 1128079..1128858 1 NC_012469.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1128858 rnhB 7686111 rnhB Streptococcus pneumoniae Taiwan19F-14 ribonuclease HII YP_002742606.1 1128079 D 487213 CDS YP_002742607.1 225861098 7686293 1128874..1130424 1 NC_012469.1 identified by match to protein family HMM PF00654; match to protein family HMM PF02080; voltage-gated chloride channel family protein 1130424 7686293 SPT_1184 Streptococcus pneumoniae Taiwan19F-14 voltage-gated chloride channel family protein YP_002742607.1 1128874 D 487213 CDS YP_002742608.1 225861099 7686394 1130918..1131988 1 NC_012469.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1131988 xerS 7686394 xerS Streptococcus pneumoniae Taiwan19F-14 site-specific tyrosine recombinase XerS YP_002742608.1 1130918 D 487213 CDS YP_002742609.1 225861100 7685726 complement(1132061..1133050) 1 NC_012469.1 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate protein ligase A 1133050 7685726 SPT_1186 Streptococcus pneumoniae Taiwan19F-14 lipoate protein ligase A YP_002742609.1 1132061 R 487213 CDS YP_002742610.1 225861101 7685217 complement(1133114..1134799) 1 NC_012469.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoyl dehydrogenase 1134799 lpdA 7685217 lpdA Streptococcus pneumoniae Taiwan19F-14 dihydrolipoyl dehydrogenase YP_002742610.1 1133114 R 487213 CDS YP_002742611.1 225861102 7687111 complement(1134863..1135906) 1 NC_012469.1 unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase 1135906 7687111 SPT_1188 Streptococcus pneumoniae Taiwan19F-14 dihydrolipoamide acetyltransferase YP_002742611.1 1134863 R 487213 CDS YP_002742612.1 225861103 7686709 complement(1136124..1137116) 1 NC_012469.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; pyruvate dehydrogenase E1 component subunit beta 1137116 7686709 SPT_1189 Streptococcus pneumoniae Taiwan19F-14 pyruvate dehydrogenase E1 component subunit beta YP_002742612.1 1136124 R 487213 CDS YP_002742613.1 225861104 7685820 complement(1137132..1138100) 1 NC_012469.1 identified by match to protein family HMM PF00676; pyruvate dehydrogenase E1 component subunit alpha 1138100 7685820 SPT_1190 Streptococcus pneumoniae Taiwan19F-14 pyruvate dehydrogenase E1 component subunit alpha YP_002742613.1 1137132 R 487213 CDS YP_002742614.1 225861105 7687057 complement(1138254..1139615) 1 NC_012469.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein 1139615 7687057 SPT_1191 Streptococcus pneumoniae Taiwan19F-14 mate efflux family protein YP_002742614.1 1138254 R 487213 CDS YP_002742615.1 225861106 7686322 complement(1139900..1141168) 1 NC_012469.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1141168 pyrC 7686322 pyrC Streptococcus pneumoniae Taiwan19F-14 dihydroorotase YP_002742615.1 1139900 R 487213 CDS YP_002742616.1 225861107 7685500 complement(1141181..1141645) 1 NC_012469.1 identified by match to protein family HMM PF00293; mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) 1141645 7685500 SPT_1193 Streptococcus pneumoniae Taiwan19F-14 mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) YP_002742616.1 1141181 R 487213 CDS YP_002742617.1 225861108 7686239 complement(1141655..1142308) 1 NC_012469.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1142308 ung 7686239 ung Streptococcus pneumoniae Taiwan19F-14 uracil-DNA glycosylase YP_002742617.1 1141655 R 487213 CDS YP_002742618.1 225861109 7686355 complement(1142613..1143092) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1143092 7686355 SPT_1195 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742618.1 1142613 R 487213 CDS YP_002742619.1 225861110 7686891 complement(1143106..1143819) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; HAD superfamily (subfamily IA) hydrolase 1143819 7686891 SPT_1196 Streptococcus pneumoniae Taiwan19F-14 HAD superfamily (subfamily IA) hydrolase YP_002742619.1 1143106 R 487213 CDS YP_002742620.1 225861111 7685758 complement(1144278..1144658) 1 NC_012469.1 identified by match to protein family HMM PF03610; match to protein family HMM TIGR02364; phosphotransferase mannnose-specific family component IIA 1144658 7685758 SPT_1197 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase mannnose-specific family component IIA YP_002742620.1 1144278 R 487213 CDS YP_002742621.1 225861112 7687092 complement(1145080..1147560) 1 NC_012469.1 identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 1147560 7687092 SPT_1198 Streptococcus pneumoniae Taiwan19F-14 pneumococcal histidine triad protein B YP_002742621.1 1145080 R 487213 CDS YP_002742622.1 225861113 7686454 complement(1147568..1148485) 1 NC_012469.1 identified by match to protein family HMM PF01297; zinc-binding lipoprotein AdcA 1148485 7686454 SPT_1199 Streptococcus pneumoniae Taiwan19F-14 zinc-binding lipoprotein AdcA YP_002742622.1 1147568 R 487213 CDS YP_002742623.1 225861114 7686027 complement(1148628..1150019) 1 NC_012469.1 identified by match to protein family HMM PF00324; amino acid permease family protein 1150019 7686027 SPT_1200 Streptococcus pneumoniae Taiwan19F-14 amino acid permease family protein YP_002742623.1 1148628 R 487213 CDS YP_002742624.1 225861115 7686681 complement(1150393..1150950) 1 NC_012469.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 1150950 7686681 SPT_1201 Streptococcus pneumoniae Taiwan19F-14 thioredoxin family protein YP_002742624.1 1150393 R 487213 CDS YP_002742625.1 225861116 7687173 complement(1150961..1151668) 1 NC_012469.1 identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein CcdA 1151668 7687173 SPT_1202 Streptococcus pneumoniae Taiwan19F-14 cytochrome c-type biogenesis protein CcdA YP_002742625.1 1150961 R 487213 CDS YP_002742626.1 225861117 7685909 complement(1151899..1152315) 1 NC_012469.1 hypothetical protein 1152315 7685909 SPT_1203 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742626.1 1151899 R 487213 CDS YP_002742627.1 225861118 7687210 complement(1152340..1152540) 1 NC_012469.1 hypothetical protein 1152540 7687210 SPT_1204 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742627.1 1152340 R 487213 CDS YP_002742628.1 225861119 7687401 1152733..1152858 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1152858 7687401 SPT_1205 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742628.1 1152733 D 487213 CDS YP_002742629.1 225861120 7685464 complement(1153006..1153335) 1 NC_012469.1 identified by match to protein family HMM PF01710; transposase 1153335 7685464 SPT_1206 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742629.1 1153006 R 487213 CDS YP_002742630.1 225861121 7685809 complement(1155040..1156803) 1 NC_012469.1 identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein 1156803 7685809 SPT_1210 Streptococcus pneumoniae Taiwan19F-14 glycerophosphoryl diester phosphodiesterase family protein YP_002742630.1 1155040 R 487213 CDS YP_002742631.1 225861122 7685887 complement(1156812..1157402) 1 NC_012469.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1157402 7685887 SPT_1211 Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III subunit epsilon YP_002742631.1 1156812 R 487213 CDS YP_002742632.1 225861123 7686559 complement(1157500..1157979) 1 NC_012469.1 identified by match to protein family HMM PF04394; hypothetical protein 1157979 7686559 SPT_1212 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742632.1 1157500 R 487213 CDS YP_002742633.1 225861124 7685537 complement(1158068..1158760) 1 NC_012469.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1158760 mtnN 7685537 mtnN Streptococcus pneumoniae Taiwan19F-14 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002742633.1 1158068 R 487213 CDS YP_002742634.1 225861125 7685986 complement(1158777..1159091) 1 NC_012469.1 hypothetical protein 1159091 7685986 SPT_1214 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742634.1 1158777 R 487213 CDS YP_002742635.1 225861126 7685640 complement(1159103..1159648) 1 NC_012469.1 identified by match to protein family HMM PF00293; ADP-ribose pyrophosphatase 1159648 7685640 SPT_1215 Streptococcus pneumoniae Taiwan19F-14 ADP-ribose pyrophosphatase YP_002742635.1 1159103 R 487213 CDS YP_002742636.1 225861127 7686975 complement(1159658..1161037) 1 NC_012469.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 1161037 glmU 7686975 glmU Streptococcus pneumoniae Taiwan19F-14 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002742636.1 1159658 R 487213 CDS YP_002742637.1 225861128 7686199 1161181..1161969 1 NC_012469.1 identified by match to protein family HMM PF01183; lyzozyme M1 1161969 7686199 SPT_1217 Streptococcus pneumoniae Taiwan19F-14 lyzozyme M1 YP_002742637.1 1161181 D 487213 CDS YP_002742638.1 225861129 7687405 1162064..1162906 1 NC_012469.1 identified by match to protein family HMM PF04018; integral membrane protein 1162906 7687405 SPT_1218 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002742638.1 1162064 D 487213 CDS YP_002742639.1 225861130 7685458 1162937..1163389 1 NC_012469.1 identified by match to protein family HMM PF04073; regulatory protein 1163389 7685458 SPT_1219 Streptococcus pneumoniae Taiwan19F-14 regulatory protein YP_002742639.1 1162937 D 487213 CDS YP_002742640.1 225861131 7685625 1163389..1164009 1 NC_012469.1 identified by match to protein family HMM PF00300; phosphoglycerate mutase 1164009 7685625 SPT_1220 Streptococcus pneumoniae Taiwan19F-14 phosphoglycerate mutase YP_002742640.1 1163389 D 487213 CDS YP_002742641.1 225861132 7685266 complement(1165228..1166169) 1 NC_012469.1 cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 1166169 prsA 7685266 prsA Streptococcus pneumoniae Taiwan19F-14 foldase protein PrsA YP_002742641.1 1165228 R 487213 CDS YP_002742642.1 225861133 7687289 complement(1166236..1166913) 1 NC_012469.1 identified by match to protein family HMM PF01596; match to protein family HMM PF08241; O-methyltransferase family protein 1166913 7687289 SPT_1223 Streptococcus pneumoniae Taiwan19F-14 O-methyltransferase family protein YP_002742642.1 1166236 R 487213 CDS YP_002742643.1 225861134 7685739 complement(1166951..1168762) 1 NC_012469.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F 1168762 pepF1 7685739 pepF1 Streptococcus pneumoniae Taiwan19F-14 oligoendopeptidase F YP_002742643.1 1166951 R 487213 CDS YP_002742644.1 225861135 7686543 complement(1168781..1169734) 1 NC_012469.1 identified by match to protein family HMM PF06054; competence protein 1169734 7686543 SPT_1225 Streptococcus pneumoniae Taiwan19F-14 competence protein YP_002742644.1 1168781 R 487213 CDS YP_002742645.1 225861136 7685800 complement(1169807..1170667) 1 NC_012469.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1170667 tehB 7685800 tehB Streptococcus pneumoniae Taiwan19F-14 tellurite resistance protein TehB YP_002742645.1 1169807 R 487213 CDS YP_002742646.1 225861137 7686226 complement(1170683..1171150) 1 NC_012469.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1171150 smpB 7686226 smpB Streptococcus pneumoniae Taiwan19F-14 SsrA-binding protein YP_002742646.1 1170683 R 487213 CDS YP_002742647.1 225861138 7686851 complement(1171113..1173467) 1 NC_012469.1 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease R 1173467 rnr 7686851 rnr Streptococcus pneumoniae Taiwan19F-14 ribonuclease R YP_002742647.1 1171113 R 487213 CDS YP_002742648.1 225861139 7687223 complement(1173569..1173802) 1 NC_012469.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 1173802 secG 7687223 secG Streptococcus pneumoniae Taiwan19F-14 preprotein translocase subunit SecG YP_002742648.1 1173569 R 487213 CDS YP_002742649.1 225861140 7685926 complement(1173842..1173991) 1 NC_012469.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1173991 rpmG 7685926 rpmG Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L33 YP_002742649.1 1173842 R 487213 CDS YP_002742650.1 225861141 7687230 complement(1173991..1175190) 1 NC_012469.1 identified by match to protein family HMM PF07690; multidrug resistance protein MdtG 1175190 7687230 SPT_1231 Streptococcus pneumoniae Taiwan19F-14 multidrug resistance protein MdtG YP_002742650.1 1173991 R 487213 CDS YP_002742651.1 225861142 7686063 complement(1175177..1175782) 1 NC_012469.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1175782 coaE 7686063 coaE Streptococcus pneumoniae Taiwan19F-14 dephospho-CoA kinase YP_002742651.1 1175177 R 487213 CDS YP_002742652.1 225861143 7686296 complement(1175782..1176606) 1 NC_012469.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1176606 mutM 7686296 mutM Streptococcus pneumoniae Taiwan19F-14 formamidopyrimidine-DNA glycosylase YP_002742652.1 1175782 R 487213 CDS YP_002742653.1 225861144 7686967 complement(1176655..1177554) 1 NC_012469.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1177554 era 7686967 era Streptococcus pneumoniae Taiwan19F-14 GTP-binding protein Era YP_002742653.1 1176655 R 487213 CDS YP_002742654.1 225861145 7686076 complement(1177571..1177966) 1 NC_012469.1 identified by match to protein family HMM PF01219; diacylglycerol kinase (dagk) (diglyceride kinase)(dgk) 1177966 7686076 SPT_1235 Streptococcus pneumoniae Taiwan19F-14 diacylglycerol kinase (dagk) (diglyceride kinase)(dgk) YP_002742654.1 1177571 R 487213 CDS YP_002742655.1 225861146 7685455 complement(1177947..1178444) 1 NC_012469.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; putative metalloprotease 1178444 7685455 SPT_1236 Streptococcus pneumoniae Taiwan19F-14 putative metalloprotease YP_002742655.1 1177947 R 487213 CDS YP_002742656.1 225861147 7686349 1178549..1180204 1 NC_012469.1 identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin/fibrinogen binding protein 1180204 7686349 SPT_1237 Streptococcus pneumoniae Taiwan19F-14 fibronectin/fibrinogen binding protein YP_002742656.1 1178549 D 487213 CDS YP_002742657.1 225861148 7687338 complement(1180265..1182373) 1 NC_012469.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01832; endo-beta-N-acetylglucosaminidase 1182373 7687338 SPT_1238 Streptococcus pneumoniae Taiwan19F-14 endo-beta-N-acetylglucosaminidase YP_002742657.1 1180265 R 487213 CDS YP_002742658.1 225861149 7686692 complement(1182472..1183410) 1 NC_012469.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 1183410 7686692 SPT_1239 Streptococcus pneumoniae Taiwan19F-14 dihydroorotate dehydrogenase 1B YP_002742658.1 1182472 R 487213 CDS YP_002742659.1 225861150 7685776 complement(1183421..1184221) 1 NC_012469.1 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 1184221 7685776 SPT_1240 Streptococcus pneumoniae Taiwan19F-14 dihydroorotate dehydrogenase electron transfer subunit YP_002742659.1 1183421 R 487213 CDS YP_002742660.1 225861151 7687358 complement(1184471..1184851) 1 NC_012469.1 identified by match to protein family HMM PF00903; lactoylglutathione lyase 1184851 7687358 SPT_1241 Streptococcus pneumoniae Taiwan19F-14 lactoylglutathione lyase YP_002742660.1 1184471 R 487213 CDS YP_002742661.1 225861152 7685232 complement(1184909..1185268) 1 NC_012469.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1185268 rplT 7685232 rplT Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L20 YP_002742661.1 1184909 R 487213 CDS YP_002742662.1 225861153 7686791 complement(1185320..1185520) 1 NC_012469.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 1185520 rpmI 7686791 rpmI Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L35 YP_002742662.1 1185320 R 487213 CDS YP_002742663.1 225861154 7685382 complement(1185553..1186110) 1 NC_012469.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1186110 infC 7685382 infC Streptococcus pneumoniae Taiwan19F-14 translation initiation factor IF-3 YP_002742663.1 1185553 R 487213 CDS YP_002742664.1 225861155 7687084 complement(1186394..1187578) 1 NC_012469.1 hypothetical protein 1187578 7687084 SPT_1245 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742664.1 1186394 R 487213 CDS YP_002742665.1 225861156 7686657 complement(1187582..1188169) 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1188169 7686657 SPT_1246 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742665.1 1187582 R 487213 CDS YP_002742666.1 225861157 7686059 complement(1188568..1190808) 1 NC_012469.1 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; DNA internalization-related competence protein ComEC/Rec2 1190808 7686059 SPT_1247 Streptococcus pneumoniae Taiwan19F-14 DNA internalization-related competence protein ComEC/Rec2 YP_002742666.1 1188568 R 487213 CDS YP_002742667.1 225861158 7685624 complement(1190792..1191442) 1 NC_012469.1 identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; competence protein 1191442 7685624 SPT_1248 Streptococcus pneumoniae Taiwan19F-14 competence protein YP_002742667.1 1190792 R 487213 CDS YP_002742668.1 225861159 7686745 complement(1191510..1192079) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1192079 7686745 SPT_1249 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742668.1 1191510 R 487213 CDS YP_002742669.1 225861160 7685903 complement(1193767..1193994) 1 NC_012469.1 TfoX N- domain family protein 1193994 7685903 SPT_1253 Streptococcus pneumoniae Taiwan19F-14 TfoX N- domain family protein YP_002742669.1 1193767 R 487213 CDS YP_002742670.1 225861161 7686774 complement(1193997..1194497) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1194497 7686774 SPT_1254 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742670.1 1193997 R 487213 CDS YP_002742671.1 225861162 7686465 1194587..1194712 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1194712 7686465 SPT_1256 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742671.1 1194587 D 487213 CDS YP_002742672.1 225861163 7686762 complement(1194690..1195658) 1 NC_012469.1 identified by match to protein family HMM PF02562; PhoH family protein 1195658 7686762 SPT_1255 Streptococcus pneumoniae Taiwan19F-14 PhoH family protein YP_002742672.1 1194690 R 487213 CDS YP_002742673.1 225861164 7686538 complement(1195744..1195959) 1 NC_012469.1 identified by match to protein family HMM PF06855; hypothetical protein 1195959 7686538 SPT_1257 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742673.1 1195744 R 487213 CDS YP_002742674.1 225861165 7686093 complement(1195968..1196861) 1 NC_012469.1 s1 RNA binding domain protein 1196861 7686093 SPT_1258 Streptococcus pneumoniae Taiwan19F-14 s1 RNA binding domain protein YP_002742674.1 1195968 R 487213 CDS YP_002742675.1 225861166 7685393 complement(1196882..1197439) 1 NC_012469.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1197439 frr 7685393 frr Streptococcus pneumoniae Taiwan19F-14 ribosome recycling factor YP_002742675.1 1196882 R 487213 CDS YP_002742676.1 225861167 7687237 complement(1197448..1198185) 1 NC_012469.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1198185 pyrH 7687237 pyrH Streptococcus pneumoniae Taiwan19F-14 uridylate kinase YP_002742676.1 1197448 R 487213 CDS YP_002742677.1 225861168 7685341 complement(1198269..1199603) 1 NC_012469.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1199603 trmFO 7685341 trmFO Streptococcus pneumoniae Taiwan19F-14 tRNA (uracil-5-)-methyltransferase Gid YP_002742677.1 1198269 R 487213 CDS YP_002742678.1 225861169 7685483 complement(1199790..1200668) 1 NC_012469.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein 1200668 7685483 SPT_1262 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742678.1 1199790 R 487213 CDS YP_002742679.1 225861170 7685223 complement(1200671..1200988) 1 NC_012469.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 1200988 7685223 SPT_1263 Streptococcus pneumoniae Taiwan19F-14 DNA replication intiation control protein YabA YP_002742679.1 1200671 R 487213 CDS YP_002742680.1 225861171 7686726 complement(1201028..1201918) 1 NC_012469.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 1201918 7686726 SPT_1264 Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III subunit delta' YP_002742680.1 1201028 R 487213 CDS YP_002742681.1 225861172 7687222 complement(1201915..1202553) 1 NC_012469.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1202553 tmk 7687222 tmk Streptococcus pneumoniae Taiwan19F-14 thymidylate kinase YP_002742681.1 1201915 R 487213 CDS YP_002742682.1 225861173 7686197 complement(1202773..1203570) 1 NC_012469.1 identified by match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00112; pyrroline-5-carboxylate reductase 1203570 proC 7686197 proC Streptococcus pneumoniae Taiwan19F-14 pyrroline-5-carboxylate reductase YP_002742682.1 1202773 R 487213 CDS YP_002742683.1 225861174 7685520 complement(1203574..1204836) 1 NC_012469.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1204836 proA 7685520 proA Streptococcus pneumoniae Taiwan19F-14 gamma-glutamyl phosphate reductase YP_002742683.1 1203574 R 487213 CDS YP_002742684.1 225861175 7685359 complement(1204846..1205955) 1 NC_012469.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1205955 proB 7685359 proB Streptococcus pneumoniae Taiwan19F-14 gamma-glutamyl kinase YP_002742684.1 1204846 R 487213 CDS YP_002742685.1 225861176 7685637 complement(1206056..1207939) 1 NC_012469.1 identified by match to protein family HMM PF00753; match to protein family HMM PF01473; choline binding protein E 1207939 7685637 SPT_1269 Streptococcus pneumoniae Taiwan19F-14 choline binding protein E YP_002742685.1 1206056 R 487213 CDS YP_002742686.1 225861177 7686724 complement(1207942..1208829) 1 NC_012469.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D) (rRNA pseudouridylate synthase D) 1208829 7686724 SPT_1270 Streptococcus pneumoniae Taiwan19F-14 ribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D) (rRNA pseudouridylate synthase D) YP_002742686.1 1207942 R 487213 CDS YP_002742687.1 225861178 7685261 complement(1208819..1209280) 1 NC_012469.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1209280 lspA 7685261 lspA Streptococcus pneumoniae Taiwan19F-14 lipoprotein signal peptidase YP_002742687.1 1208819 R 487213 CDS YP_002742688.1 225861179 7685388 complement(1209277..1210185) 1 NC_012469.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; regulatory function on capsule expression in group B streptococci 1210185 7685388 SPT_1272 Streptococcus pneumoniae Taiwan19F-14 regulatory function on capsule expression in group B streptococci YP_002742688.1 1209277 R 487213 CDS YP_002742689.1 225861180 7685330 1210178..1210375 1 NC_012469.1 hypothetical protein 1210375 7685330 SPT_1273 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742689.1 1210178 D 487213 CDS YP_002742690.1 225861181 7685941 complement(1210427..1211098) 1 NC_012469.1 identified by match to protein family HMM PF02517; caax amino protease family 1211098 7685941 SPT_1274 Streptococcus pneumoniae Taiwan19F-14 caax amino protease family YP_002742690.1 1210427 R 487213 CDS YP_002742691.1 225861182 7686441 complement(1211152..1211373) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1211373 7686441 SPT_1275 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742691.1 1211152 R 487213 CDS YP_002742692.1 225861183 7685653 1211645..1212454 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1212454 7685653 SPT_1276 Streptococcus pneumoniae Taiwan19F-14 Cof family protein YP_002742692.1 1211645 D 487213 CDS YP_002742693.1 225861184 7686163 complement(1212635..1213510) 1 NC_012469.1 identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381; N-carbamoylputrescine amidase 1213510 aguB 7686163 aguB Streptococcus pneumoniae Taiwan19F-14 N-carbamoylputrescine amidase YP_002742693.1 1212635 R 487213 CDS YP_002742694.1 225861185 7686101 complement(1213520..1214605) 1 NC_012469.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 1214605 aguA 7686101 aguA Streptococcus pneumoniae Taiwan19F-14 agmatine deiminase YP_002742694.1 1213520 R 487213 CDS YP_002742695.1 225861186 7685845 complement(1214602..1215729) 1 NC_012469.1 identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 1215729 nspC 7685845 nspC Streptococcus pneumoniae Taiwan19F-14 carboxynorspermidine decarboxylase YP_002742695.1 1214602 R 487213 CDS YP_002742696.1 225861187 7686080 complement(1215729..1216988) 1 NC_012469.1 identified by match to protein family HMM PF03435; saccharopine dehydrogenase 1216988 lys 7686080 lys Streptococcus pneumoniae Taiwan19F-14 saccharopine dehydrogenase YP_002742696.1 1215729 R 487213 CDS YP_002742697.1 225861188 7686942 complement(1216985..1217845) 1 NC_012469.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 1217845 speE 7686942 speE Streptococcus pneumoniae Taiwan19F-14 spermidine synthase YP_002742697.1 1216985 R 487213 CDS YP_002742698.1 225861189 7686250 complement(1217876..1218013) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1218013 7686250 SPT_1282 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742698.1 1217876 R 487213 CDS YP_002742699.1 225861190 7686342 1218100..1218627 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1218627 7686342 SPT_1283 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742699.1 1218100 D 487213 CDS YP_002742700.1 225861191 7687294 1218579..1218815 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1218815 7687294 SPT_1285 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742700.1 1218579 D 487213 CDS YP_002742701.1 225861192 7686962 complement(1218781..1220256) 1 NC_012469.1 arginine decarboxylase 1220256 7686962 SPT_1284 Streptococcus pneumoniae Taiwan19F-14 arginine decarboxylase YP_002742701.1 1218781 R 487213 CDS YP_002742702.1 225861193 7686139 1220963..1221838 1 NC_012469.1 identified by match to protein family HMM PF00665; transposase 1221838 7686139 SPT_1286 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742702.1 1220963 D 487213 CDS YP_002742703.1 225861194 7686062 1221984..1222412 1 NC_012469.1 identified by match to protein family HMM PF01988; integral membrane protein 1222412 7686062 SPT_1287 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002742703.1 1221984 D 487213 CDS YP_002742704.1 225861195 7685449 complement(1222455..1224443) 1 NC_012469.1 identified by match to protein family HMM PF02687; antimicrobial peptide ABC transporter permease 1224443 7685449 SPT_1288 Streptococcus pneumoniae Taiwan19F-14 antimicrobial peptide ABC transporter permease YP_002742704.1 1222455 R 487213 CDS YP_002742705.1 225861196 7686599 complement(1224445..1225203) 1 NC_012469.1 identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA 1225203 7686599 SPT_1289 Streptococcus pneumoniae Taiwan19F-14 bacitracin export ATP-binding protein BceA YP_002742705.1 1224445 R 487213 CDS YP_002742706.1 225861197 7686323 1225632..1225823 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1225823 7686323 SPT_1290 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742706.1 1225632 D 487213 CDS YP_002742707.1 225861198 7686437 complement(1226177..1226449) 1 NC_012469.1 identified by match to protein family HMM PF04024; PspC domain family 1226449 7686437 SPT_1291 Streptococcus pneumoniae Taiwan19F-14 PspC domain family YP_002742707.1 1226177 R 487213 CDS YP_002742708.1 225861199 7685511 complement(1226508..1226957) 1 NC_012469.1 identified by match to protein family HMM PF03926; hypothetical protein 1226957 7685511 SPT_1292 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742708.1 1226508 R 487213 CDS YP_002742709.1 225861200 7685875 complement(1226944..1229073) 1 NC_012469.1 identified by match to protein family HMM PF00575; S1 RNA binding domain protein 1229073 7685875 SPT_1293 Streptococcus pneumoniae Taiwan19F-14 S1 RNA binding domain protein YP_002742709.1 1226944 R 487213 CDS YP_002742710.1 225861201 7687080 1229353..1229484 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1229484 7687080 SPT_1294 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742710.1 1229353 D 487213 CDS YP_002742711.1 225861202 7686879 1229485..1230390 1 NC_012469.1 identified by match to protein family HMM PF03773; membrane protein 1230390 7686879 SPT_1295 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002742711.1 1229485 D 487213 CDS YP_002742712.1 225861203 7687070 1230387..1231202 1 NC_012469.1 identified by match to protein family HMM PF09323; ABC transporter substrate-binding protein 1231202 7687070 SPT_1296 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002742712.1 1230387 D 487213 CDS YP_002742713.1 225861204 7687274 complement(1231332..1232048) 1 NC_012469.1 hypothetical protein 1232048 7687274 SPT_1297 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742713.1 1231332 R 487213 CDS YP_002742714.1 225861205 7685291 complement(1232083..1232364) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1232364 7685291 SPT_1298 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742714.1 1232083 R 487213 CDS YP_002742715.1 225861206 7687189 1232507..1232890 1 NC_012469.1 mobile genetic element 1232890 7687189 SPT_1299 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002742715.1 1232507 D 487213 CDS YP_002742716.1 225861207 7686723 complement(1232997..1233869) 1 NC_012469.1 lipoprotein, putative 1233869 7686723 SPT_1300 Streptococcus pneumoniae Taiwan19F-14 lipoprotein, putative YP_002742716.1 1232997 R 487213 CDS YP_002742717.1 225861208 7685856 1235381..1236727 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 1236727 7685856 SPT_1301 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742717.1 1235381 D 487213 CDS YP_002742718.1 225861209 7687251 complement(1237230..1238735) 1 NC_012469.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1238735 pyk 7687251 pyk Streptococcus pneumoniae Taiwan19F-14 pyruvate kinase YP_002742718.1 1237230 R 487213 CDS YP_002742719.1 225861210 7685730 complement(1238794..1239801) 1 NC_012469.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1239801 pfkA 7685730 pfkA Streptococcus pneumoniae Taiwan19F-14 6-phosphofructokinase YP_002742719.1 1238794 R 487213 CDS YP_002742720.1 225861211 7685766 complement(1239884..1242985) 1 NC_012469.1 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 1242985 dnaE 7685766 dnaE Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III DnaE YP_002742720.1 1239884 R 487213 CDS YP_002742721.1 225861212 7685807 1243332..1245605 1 NC_012469.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1245605 7685807 SPT_1305 Streptococcus pneumoniae Taiwan19F-14 x-prolyl-dipeptidyl aminopeptidase YP_002742721.1 1243332 D 487213 CDS YP_002742722.1 225861213 7685954 1245622..1246092 1 NC_012469.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; arginine repressor 1246092 7685954 SPT_1306 Streptococcus pneumoniae Taiwan19F-14 arginine repressor YP_002742722.1 1245622 D 487213 CDS YP_002742723.1 225861214 7685349 complement(1246209..1246364) 1 NC_012469.1 chlorohydrolase 1246364 7685349 SPT_1307 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742723.1 1246209 R 487213 CDS YP_002742724.1 225861215 7687145 complement(1246635..1249985) 1 NC_012469.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; type I restriction-modification system R subunit 1249985 7687145 SPT_1308 Streptococcus pneumoniae Taiwan19F-14 type I restriction-modification system R subunit YP_002742724.1 1246635 R 487213 CDS YP_002742725.1 225861216 7685374 complement(1250015..1251058) 1 NC_012469.1 identified by match to protein family HMM PF01420; type I restriction-modification system, S subunit 1251058 7685374 SPT_1309 Streptococcus pneumoniae Taiwan19F-14 type I restriction-modification system, S subunit YP_002742725.1 1250015 R 487213 CDS YP_002742726.1 225861217 7685691 complement(1251092..1252057) 1 NC_012469.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; integrase/recombinase, phage integrase family 1252057 7685691 SPT_1310 Streptococcus pneumoniae Taiwan19F-14 integrase/recombinase, phage integrase family YP_002742726.1 1251092 R 487213 CDS YP_002742727.1 225861218 7686187 complement(1252175..1252588) 1 NC_012469.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550; prophage maintenance system killer protein 1252588 7686187 SPT_1311 Streptococcus pneumoniae Taiwan19F-14 prophage maintenance system killer protein YP_002742727.1 1252175 R 487213 CDS YP_002742728.1 225861219 7686176 complement(1252585..1252821) 1 NC_012469.1 hypothetical protein 1252821 7686176 SPT_1312 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742728.1 1252585 R 487213 CDS YP_002742729.1 225861220 7686257 complement(1252881..1254002) 1 NC_012469.1 identified by match to protein family HMM PF01420; type I restriction-modification system, S subunit, putative 1254002 7686257 SPT_1313 Streptococcus pneumoniae Taiwan19F-14 type I restriction-modification system, S subunit, putative YP_002742729.1 1252881 R 487213 CDS YP_002742730.1 225861221 7687385 complement(1254015..1255508) 1 NC_012469.1 identified by match to protein family HMM PF02384; type I restriction modification enzyme methylase subunit 1255508 7687385 SPT_1314 Streptococcus pneumoniae Taiwan19F-14 type I restriction modification enzyme methylase subunit YP_002742730.1 1254015 R 487213 CDS YP_002742731.1 225861222 7687026 complement(1255631..1255756) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1255756 7687026 SPT_1315 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742731.1 1255631 R 487213 CDS YP_002742732.1 225861223 7685659 complement(1256016..1257182) 1 NC_012469.1 carbamoylphosphate synthase large subunit 1257182 7685659 SPT_1316 Streptococcus pneumoniae Taiwan19F-14 carbamoylphosphate synthase large subunit YP_002742732.1 1256016 R 487213 CDS YP_002742733.1 225861224 7686595 complement(1257195..1257602) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1257602 7686595 SPT_1317 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742733.1 1257195 R 487213 CDS YP_002742734.1 225861225 7686439 complement(1257599..1257934) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1257934 7686439 SPT_1318 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742734.1 1257599 R 487213 CDS YP_002742735.1 225861226 7686540 complement(1257956..1258780) 1 NC_012469.1 identified by match to protein family HMM PF00756; putative esterase superfamily 1258780 7686540 SPT_1319 Streptococcus pneumoniae Taiwan19F-14 putative esterase superfamily YP_002742735.1 1257956 R 487213 CDS YP_002742736.1 225861227 7686290 complement(1258917..1260131) 1 NC_012469.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1260131 thiI 7686290 thiI Streptococcus pneumoniae Taiwan19F-14 thiamine biosynthesis protein ThiI YP_002742736.1 1258917 R 487213 CDS YP_002742737.1 225861228 7686482 complement(1260140..1261282) 1 NC_012469.1 identified by match to protein family HMM PF00266; cysteine desulfurase 1261282 7686482 SPT_1321 Streptococcus pneumoniae Taiwan19F-14 cysteine desulfurase YP_002742737.1 1260140 R 487213 CDS YP_002742738.1 225861229 7687362 1261420..1261848 1 NC_012469.1 hypothetical protein 1261848 7687362 SPT_1322 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742738.1 1261420 D 487213 CDS YP_002742739.1 225861230 7686641 complement(1261892..1264117) 1 NC_012469.1 identified by match to protein family HMM PF01580; DNA translocase ftsk 1264117 7686641 SPT_1323 Streptococcus pneumoniae Taiwan19F-14 DNA translocase ftsk YP_002742739.1 1261892 R 487213 CDS YP_002742740.1 225861231 7686255 complement(1264281..1266233) 1 NC_012469.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; PTS system, fructose subfamily, IIABC component 1266233 fruA 7686255 fruA Streptococcus pneumoniae Taiwan19F-14 PTS system, fructose subfamily, IIABC component YP_002742740.1 1264281 R 487213 CDS YP_002742741.1 225861232 7686128 complement(1266230..1267141) 1 NC_012469.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase 1267141 pfkB 7686128 pfkB Streptococcus pneumoniae Taiwan19F-14 1-phosphofructokinase YP_002742741.1 1266230 R 487213 CDS YP_002742742.1 225861233 7687099 complement(1267138..1267878) 1 NC_012469.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; lactose phosphotransferase system repressor 1267878 7687099 SPT_1326 Streptococcus pneumoniae Taiwan19F-14 lactose phosphotransferase system repressor YP_002742742.1 1267138 R 487213 CDS YP_002742743.1 225861234 7686581 complement(1269314..1270345) 1 NC_012469.1 identified by match to protein family HMM PF01594; membrane protein 1270345 7686581 SPT_1328 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002742743.1 1269314 R 487213 CDS YP_002742744.1 225861235 7686808 1270526..1271767 1 NC_012469.1 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; penicillin-binding protein 3 1271767 7686808 SPT_1329 Streptococcus pneumoniae Taiwan19F-14 penicillin-binding protein 3 YP_002742744.1 1270526 D 487213 CDS YP_002742745.1 225861236 7686398 complement(1271966..1273378) 1 NC_012469.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980; FeS assembly protein SufB 1273378 sufB 7686398 sufB Streptococcus pneumoniae Taiwan19F-14 FeS assembly protein SufB YP_002742745.1 1271966 R 487213 CDS YP_002742746.1 225861237 7686719 complement(1273432..1273872) 1 NC_012469.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994; SUF system FeS assembly protein, NifU family 1273872 7686719 SPT_1331 Streptococcus pneumoniae Taiwan19F-14 SUF system FeS assembly protein, NifU family YP_002742746.1 1273432 R 487213 CDS YP_002742747.1 225861238 7687014 complement(1273859..1275085) 1 NC_012469.1 identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979; cysteine desulfurase (Selenocysteine lyase) (Selenocysteine reductase) (Selenocysteine beta-lyase) (SCL) 1275085 7687014 SPT_1332 Streptococcus pneumoniae Taiwan19F-14 cysteine desulfurase (Selenocysteine lyase) (Selenocysteine reductase) (Selenocysteine beta-lyase) (SCL) YP_002742747.1 1273859 R 487213 CDS YP_002742748.1 225861239 7685692 complement(1275096..1276358) 1 NC_012469.1 identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981; FeS assembly protein SufD 1276358 sufD 7685692 sufD Streptococcus pneumoniae Taiwan19F-14 FeS assembly protein SufD YP_002742748.1 1275096 R 487213 CDS YP_002742749.1 225861240 7685994 complement(1276386..1277156) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; FeS assembly ATPase SufC 1277156 sufC 7685994 sufC Streptococcus pneumoniae Taiwan19F-14 FeS assembly ATPase SufC YP_002742749.1 1276386 R 487213 CDS YP_002742750.1 225861241 7687121 complement(1277306..1277428) 1 NC_012469.1 identified by match to protein family HMM PF01610; hypothetical protein 1277428 7687121 SPT_1335 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742750.1 1277306 R 487213 CDS YP_002742751.1 225861242 7686522 complement(1277528..1279183) 1 NC_012469.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1279183 7686522 SPT_1336 Streptococcus pneumoniae Taiwan19F-14 DNA polymerase III subunits gamma and tau YP_002742751.1 1277528 R 487213 CDS YP_002742752.1 225861243 7685847 complement(1279183..1279680) 1 NC_012469.1 GAF domain-containing protein 1279680 7685847 SPT_1337 Streptococcus pneumoniae Taiwan19F-14 GAF domain-containing protein YP_002742752.1 1279183 R 487213 CDS YP_002742753.1 225861244 7685364 complement(1281266..1282468) 1 NC_012469.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1282468 rpsA 7685364 rpsA Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S1 YP_002742753.1 1281266 R 487213 CDS YP_002742754.1 225861245 7685588 complement(1282841..1283071) 1 NC_012469.1 hypothetical protein 1283071 7685588 SPT_1343 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742754.1 1282841 R 487213 CDS YP_002742755.1 225861246 7687357 complement(1283239..1283883) 1 NC_012469.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 1283883 pcp1 7687357 pcp1 Streptococcus pneumoniae Taiwan19F-14 pyrrolidone-carboxylate peptidase YP_002742755.1 1283239 R 487213 CDS YP_002742756.1 225861247 7685830 complement(1283898..1284821) 1 NC_012469.1 identified by match to protein family HMM PF06166; permease 1284821 7685830 SPT_1345 Streptococcus pneumoniae Taiwan19F-14 permease YP_002742756.1 1283898 R 487213 CDS YP_002742757.1 225861248 7686756 complement(1284818..1285507) 1 NC_012469.1 identified by match to protein family HMM PF06149; permease 1285507 7686756 SPT_1346 Streptococcus pneumoniae Taiwan19F-14 permease YP_002742757.1 1284818 R 487213 CDS YP_002742758.1 225861249 7685353 complement(1285572..1286276) 1 NC_012469.1 hypothetical protein 1286276 7685353 SPT_1347 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742758.1 1285572 R 487213 CDS YP_002742759.1 225861250 7686400 complement(1286332..1287354) 1 NC_012469.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1287354 ilvE 7686400 ilvE Streptococcus pneumoniae Taiwan19F-14 branched-chain amino acid aminotransferase YP_002742759.1 1286332 R 487213 CDS YP_002742760.1 225861251 7685406 complement(1287486..1289966) 1 NC_012469.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1289966 parC 7685406 parC Streptococcus pneumoniae Taiwan19F-14 DNA topoisomerase IV subunit A YP_002742760.1 1287486 R 487213 CDS YP_002742761.1 225861252 7686971 complement(1290131..1290256) 1 NC_012469.1 hypothetical protein 1290256 7686971 SPT_1350 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742761.1 1290131 R 487213 CDS YP_002742762.1 225861253 7686068 complement(1290377..1292320) 1 NC_012469.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1292320 parE 7686068 parE Streptococcus pneumoniae Taiwan19F-14 DNA topoisomerase IV subunit B YP_002742762.1 1290377 R 487213 CDS YP_002742763.1 225861254 7685813 1292456..1293097 1 NC_012469.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1293097 7685813 SPT_1352 Streptococcus pneumoniae Taiwan19F-14 putative glycerol-3-phosphate acyltransferase PlsY YP_002742763.1 1292456 D 487213 CDS YP_002742764.1 225861255 7686393 complement(1293142..1293975) 1 NC_012469.1 identified by match to protein family HMM PF00665; integrase core domain protein 1293975 7686393 SPT_1353 Streptococcus pneumoniae Taiwan19F-14 integrase core domain protein YP_002742764.1 1293142 R 487213 CDS YP_002742765.1 225861256 7685295 complement(1294498..1295454) 1 NC_012469.1 identified by match to protein family HMM PF02653; ribose/galactose ABC transporter permease 1295454 7685295 SPT_1355 Streptococcus pneumoniae Taiwan19F-14 ribose/galactose ABC transporter permease YP_002742765.1 1294498 R 487213 CDS YP_002742766.1 225861257 7687377 complement(1295457..1296515) 1 NC_012469.1 identified by match to protein family HMM PF02653; ribose/galactose ABC transporter permease 1296515 7687377 SPT_1356 Streptococcus pneumoniae Taiwan19F-14 ribose/galactose ABC transporter permease YP_002742766.1 1295457 R 487213 CDS YP_002742767.1 225861258 7685398 complement(1296508..1298043) 1 NC_012469.1 identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA 1298043 7685398 SPT_1357 Streptococcus pneumoniae Taiwan19F-14 ribose import ATP-binding protein RbsA YP_002742767.1 1296508 R 487213 CDS YP_002742768.1 225861259 7685301 complement(1298187..1299239) 1 NC_012469.1 identified by match to protein family HMM PF02608; lipoprotein 1299239 7685301 SPT_1358 Streptococcus pneumoniae Taiwan19F-14 lipoprotein YP_002742768.1 1298187 R 487213 CDS YP_002742769.1 225861260 7686729 complement(1299330..1299719) 1 NC_012469.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1299719 cdd 7686729 cdd Streptococcus pneumoniae Taiwan19F-14 cytidine deaminase YP_002742769.1 1299330 R 487213 CDS YP_002742770.1 225861261 7685258 complement(1299706..1300368) 1 NC_012469.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1300368 deoC 7685258 deoC Streptococcus pneumoniae Taiwan19F-14 deoxyribose-phosphate aldolase YP_002742770.1 1299706 R 487213 CDS YP_002742771.1 225861262 7686447 complement(1300386..1301663) 1 NC_012469.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 1301663 7686447 SPT_1361 Streptococcus pneumoniae Taiwan19F-14 pyrimidine-nucleoside phosphorylase YP_002742771.1 1300386 R 487213 CDS YP_002742772.1 225861263 7686584 complement(1301660..1302241) 1 NC_012469.1 identified by match to protein family HMM PF05175; methyltransferase small domain superfamily 1302241 7686584 SPT_1362 Streptococcus pneumoniae Taiwan19F-14 methyltransferase small domain superfamily YP_002742772.1 1301660 R 487213 CDS YP_002742773.1 225861264 7686676 complement(1302624..1302860) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1302860 7686676 SPT_1363 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742773.1 1302624 R 487213 CDS YP_002742774.1 225861265 7686122 1303050..1303970 1 NC_012469.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1303970 coaA 7686122 coaA Streptococcus pneumoniae Taiwan19F-14 pantothenate kinase YP_002742774.1 1303050 D 487213 CDS YP_002742775.1 225861266 7686047 1304038..1304274 1 NC_012469.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1304274 rpsT 7686047 rpsT Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S20 YP_002742775.1 1304038 D 487213 CDS YP_002742776.1 225861267 7686700 1304327..1304851 1 NC_012469.1 topology modulation protein 1304851 7686700 SPT_1366 Streptococcus pneumoniae Taiwan19F-14 topology modulation protein YP_002742776.1 1304327 D 487213 CDS YP_002742777.1 225861268 7686653 complement(1304874..1305584) 1 NC_012469.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 1305584 deoD 7686653 deoD Streptococcus pneumoniae Taiwan19F-14 purine nucleoside phosphorylase YP_002742777.1 1304874 R 487213 CDS YP_002742778.1 225861269 7685386 complement(1306242..1306754) 1 NC_012469.1 hemolysin-related protein 1306754 7685386 SPT_1368 Streptococcus pneumoniae Taiwan19F-14 hemolysin-related protein YP_002742778.1 1306242 R 487213 CDS YP_002742779.1 225861270 7686132 complement(1306779..1307354) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1307354 7686132 SPT_1369 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742779.1 1306779 R 487213 CDS YP_002742780.1 225861271 7685315 complement(1307364..1307771) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1307771 7685315 SPT_1370 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742780.1 1307364 R 487213 CDS YP_002742781.1 225861272 7687285 complement(1308235..1309044) 1 NC_012469.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1309044 7687285 SPT_1371 Streptococcus pneumoniae Taiwan19F-14 purine nucleoside phosphorylase YP_002742781.1 1308235 R 487213 CDS YP_002742782.1 225861273 7685855 complement(1309060..1309602) 1 NC_012469.1 identified by match to protein family HMM PF08002; hypothetical protein 1309602 7685855 SPT_1372 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742782.1 1309060 R 487213 CDS YP_002742783.1 225861274 7686167 complement(1309604..1310815) 1 NC_012469.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1310815 deoB 7686167 deoB Streptococcus pneumoniae Taiwan19F-14 phosphopentomutase YP_002742783.1 1309604 R 487213 CDS YP_002742784.1 225861275 7685746 complement(1310829..1311512) 1 NC_012469.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1311512 rpiA 7685746 rpiA Streptococcus pneumoniae Taiwan19F-14 ribose-5-phosphate isomerase A YP_002742784.1 1310829 R 487213 CDS YP_002742785.1 225861276 7686533 complement(1311794..1312666) 1 NC_012469.1 identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196; putative YjeF homolog, C-terminus 1312666 7686533 SPT_1375 Streptococcus pneumoniae Taiwan19F-14 putative YjeF homolog, C-terminus YP_002742785.1 1311794 R 487213 CDS YP_002742786.1 225861277 7685823 complement(1312808..1313686) 1 NC_012469.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1313686 7685823 SPT_1376 Streptococcus pneumoniae Taiwan19F-14 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002742786.1 1312808 R 487213 CDS YP_002742787.1 225861278 7686824 complement(1313819..1314553) 1 NC_012469.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 1314553 7686824 SPT_1377 Streptococcus pneumoniae Taiwan19F-14 glutamine transport ATP-binding protein GlnQ YP_002742787.1 1313819 R 487213 CDS YP_002742788.1 225861279 7686030 complement(1314553..1315182) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1315182 7686030 SPT_1378 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter permease YP_002742788.1 1314553 R 487213 CDS YP_002742789.1 225861280 7685914 1315424..1315654 1 NC_012469.1 identified by match to protein family HMM PF08796; hypothetical protein 1315654 7685914 SPT_1379 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742789.1 1315424 D 487213 CDS YP_002742790.1 225861281 7687122 1315883..1318141 1 NC_012469.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728; negative regulator of genetic competence ClpC/mecB 1318141 7687122 SPT_1380 Streptococcus pneumoniae Taiwan19F-14 negative regulator of genetic competence ClpC/mecB YP_002742790.1 1315883 D 487213 CDS YP_002742791.1 225861282 7686917 1318600..1318848 1 NC_012469.1 hypothetical protein 1318848 7686917 SPT_1381 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742791.1 1318600 D 487213 CDS YP_002742792.1 225861283 7687182 complement(1318887..1319216) 1 NC_012469.1 identified by match to protein family HMM PF01710; transposase 1319216 7687182 SPT_1382 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742792.1 1318887 R 487213 CDS YP_002742793.1 225861284 7686317 1319486..1319749 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1319749 7686317 SPT_1383 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742793.1 1319486 D 487213 CDS YP_002742794.1 225861285 7686476 1319914..1320213 1 NC_012469.1 identified by match to protein family HMM PF08860; hypothetical protein 1320213 7686476 SPT_1384 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742794.1 1319914 D 487213 CDS YP_002742795.1 225861286 7687287 complement(1320322..1321155) 1 NC_012469.1 identified by match to protein family HMM PF00665; integrase core domain protein 1321155 7687287 SPT_1385 Streptococcus pneumoniae Taiwan19F-14 integrase core domain protein YP_002742795.1 1320322 R 487213 CDS YP_002742796.1 225861287 7686622 complement(1321155..1321277) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1321277 7686622 SPT_1386 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742796.1 1321155 R 487213 CDS YP_002742797.1 225861288 7687226 1321835..1322185 1 NC_012469.1 identified by match to protein family HMM PF05717; transposase 1322185 7687226 SPT_1388 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742797.1 1321835 D 487213 CDS YP_002742798.1 225861289 7685982 complement(1323986..1325713) 1 NC_012469.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 1325713 ezrA 7685982 ezrA Streptococcus pneumoniae Taiwan19F-14 septation ring formation regulator EzrA YP_002742798.1 1323986 R 487213 CDS YP_002742799.1 225861290 7685715 complement(1325795..1327741) 1 NC_012469.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 1327741 gyrB 7685715 gyrB Streptococcus pneumoniae Taiwan19F-14 DNA gyrase subunit B YP_002742799.1 1325795 R 487213 CDS YP_002742800.1 225861291 7685891 complement(1327756..1328319) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphoglycolate phosphatase 1328319 7685891 SPT_1394 Streptococcus pneumoniae Taiwan19F-14 phosphoglycolate phosphatase YP_002742800.1 1327756 R 487213 CDS YP_002742801.1 225861292 7686563 complement(1328404..1328958) 1 NC_012469.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; putative 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein 1328958 7686563 SPT_1395 Streptococcus pneumoniae Taiwan19F-14 putative 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein YP_002742801.1 1328404 R 487213 CDS YP_002742802.1 225861293 7686827 complement(1328969..1330192) 1 NC_012469.1 identified by match to protein family HMM PF01098; RodA 1330192 7686827 SPT_1396 Streptococcus pneumoniae Taiwan19F-14 RodA YP_002742802.1 1328969 R 487213 CDS YP_002742803.1 225861294 7686087 complement(1330229..1332679) 1 NC_012469.1 unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 1332679 7686087 SPT_1397 Streptococcus pneumoniae Taiwan19F-14 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon YP_002742803.1 1330229 R 487213 CDS YP_002742804.1 225861295 7685992 complement(1332879..1333808) 1 NC_012469.1 identified by match to protein family HMM PF01136; protease 1333808 7685992 SPT_1398 Streptococcus pneumoniae Taiwan19F-14 protease YP_002742804.1 1332879 R 487213 CDS YP_002742805.1 225861296 7686348 1333948..1334235 1 NC_012469.1 hypothetical protein 1334235 7686348 SPT_1399 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742805.1 1333948 D 487213 CDS YP_002742806.1 225861297 7686994 complement(1334269..1335603) 1 NC_012469.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein CiaH 1335603 7686994 SPT_1400 Streptococcus pneumoniae Taiwan19F-14 sensor protein CiaH YP_002742806.1 1334269 R 487213 CDS YP_002742807.1 225861298 7686960 complement(1335593..1336267) 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein CiaR 1336267 7686960 SPT_1401 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulatory protein CiaR YP_002742807.1 1335593 R 487213 CDS YP_002742808.1 225861299 7687292 complement(1336376..1338922) 1 NC_012469.1 identified by match to protein family HMM PF01433; aminopeptidase N 1338922 7687292 SPT_1402 Streptococcus pneumoniae Taiwan19F-14 aminopeptidase N YP_002742808.1 1336376 R 487213 CDS YP_002742809.1 225861300 7687162 complement(1339045..1339485) 1 NC_012469.1 identified by match to protein family HMM PF06171; hypothetical protein 1339485 7687162 SPT_1403 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742809.1 1339045 R 487213 CDS YP_002742810.1 225861301 7686457 complement(1339460..1340329) 1 NC_012469.1 identified by match to protein family HMM PF02896; PEP-utilizing enzyme family protein 1340329 7686457 SPT_1404 Streptococcus pneumoniae Taiwan19F-14 PEP-utilizing enzyme family protein YP_002742810.1 1339460 R 487213 CDS YP_002742811.1 225861302 7686201 complement(1340307..1340807) 1 NC_012469.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1340807 7686201 SPT_1405 Streptococcus pneumoniae Taiwan19F-14 MutT/nudix family protein YP_002742811.1 1340307 R 487213 CDS YP_002742812.1 225861303 7685495 complement(1340818..1341516) 1 NC_012469.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1341516 fabG 7685495 fabG Streptococcus pneumoniae Taiwan19F-14 3-ketoacyl-ACP reductase YP_002742812.1 1340818 R 487213 CDS YP_002742813.1 225861304 7685673 complement(1341509..1341745) 1 NC_012469.1 hypothetical protein 1341745 7685673 SPT_1407 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742813.1 1341509 R 487213 CDS YP_002742814.1 225861305 7685403 complement(1341841..1342767) 1 NC_012469.1 identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family 1342767 7685403 SPT_1408 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase, aldo/keto reductase family YP_002742814.1 1341841 R 487213 CDS YP_002742815.1 225861306 7685264 complement(1342842..1343657) 1 NC_012469.1 hypothetical protein 1343657 7685264 SPT_1409 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742815.1 1342842 R 487213 CDS YP_002742816.1 225861307 7685356 complement(1343661..1343981) 1 NC_012469.1 identified by match to protein family HMM PF03551; transcriptional regulator, PadR family 1343981 7685356 SPT_1410 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, PadR family YP_002742816.1 1343661 R 487213 CDS YP_002742817.1 225861308 7685812 complement(1344071..1344532) 1 NC_012469.1 hypothetical protein 1344532 7685812 SPT_1411 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742817.1 1344071 R 487213 CDS YP_002742818.1 225861309 7686742 complement(1344582..1346579) 1 NC_012469.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1346579 metG 7686742 metG Streptococcus pneumoniae Taiwan19F-14 methionyl-tRNA synthetase YP_002742818.1 1344582 R 487213 CDS YP_002742819.1 225861310 7687322 complement(1346703..1347962) 1 NC_012469.1 identified by match to protein family HMM PF02687; antimicrobial peptide ABC transporter permease 1347962 7687322 SPT_1413 Streptococcus pneumoniae Taiwan19F-14 antimicrobial peptide ABC transporter permease YP_002742819.1 1346703 R 487213 CDS YP_002742820.1 225861311 7686878 complement(1347964..1348665) 1 NC_012469.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 1348665 7686878 SPT_1414 Streptococcus pneumoniae Taiwan19F-14 macrolide export ATP-binding/permease protein MacB YP_002742820.1 1347964 R 487213 CDS YP_002742821.1 225861312 7685974 complement(1348649..1349848) 1 NC_012469.1 identified by match to protein family HMM TIGR01730; membrane-fusion protein 1349848 7685974 SPT_1415 Streptococcus pneumoniae Taiwan19F-14 membrane-fusion protein YP_002742821.1 1348649 R 487213 CDS YP_002742822.1 225861313 7685865 1350134..1351480 1 NC_012469.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1351480 gor 7685865 gor Streptococcus pneumoniae Taiwan19F-14 glutathione reductase YP_002742822.1 1350134 D 487213 CDS YP_002742823.1 225861314 7686445 1351677..1352213 1 NC_012469.1 identified by match to protein family HMM PF02632; biotin synthase 1352213 7686445 SPT_1417 Streptococcus pneumoniae Taiwan19F-14 biotin synthase YP_002742823.1 1351677 D 487213 CDS YP_002742824.1 225861315 7686120 1352276..1352422 1 NC_012469.1 chlorohydrolase 1352422 7686120 SPT_1419 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742824.1 1352276 D 487213 CDS YP_002742825.1 225861316 7685700 complement(1352419..1352634) 1 NC_012469.1 hypothetical protein 1352634 7685700 SPT_1418 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742825.1 1352419 R 487213 CDS YP_002742826.1 225861317 7686686 1352732..1353052 1 NC_012469.1 hypothetical protein 1353052 7686686 SPT_1420 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742826.1 1352732 D 487213 CDS YP_002742827.1 225861318 7686683 complement(1353082..1353420) 1 NC_012469.1 identified by match to protein family HMM PF03477; oxygen-sensitive ribonucleoside-triphosphate reductase 1353420 7686683 SPT_1421 Streptococcus pneumoniae Taiwan19F-14 oxygen-sensitive ribonucleoside-triphosphate reductase YP_002742827.1 1353082 R 487213 CDS YP_002742828.1 225861319 7686152 complement(1353432..1354151) 1 NC_012469.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1354151 trmD 7686152 trmD Streptococcus pneumoniae Taiwan19F-14 tRNA (guanine-N(1)-)-methyltransferase YP_002742828.1 1353432 R 487213 CDS YP_002742829.1 225861320 7687395 complement(1354141..1354659) 1 NC_012469.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1354659 rimM 7687395 rimM Streptococcus pneumoniae Taiwan19F-14 16S rRNA-processing protein RimM YP_002742829.1 1354141 R 487213 CDS YP_002742830.1 225861321 7685304 complement(1354690..1355478) 1 NC_012469.1 identified by match to protein family HMM PF00561; hydrolase, alpha/beta fold family, putative 1355478 7685304 SPT_1424 Streptococcus pneumoniae Taiwan19F-14 hydrolase, alpha/beta fold family, putative YP_002742830.1 1354690 R 487213 CDS YP_002742831.1 225861322 7686395 1356025..1357371 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 1357371 7686395 SPT_1425 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742831.1 1356025 D 487213 CDS YP_002742832.1 225861323 7685530 complement(1357832..1359028) 1 NC_012469.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1359028 tuf 7685530 tuf Streptococcus pneumoniae Taiwan19F-14 elongation factor Tu YP_002742832.1 1357832 R 487213 CDS YP_002742833.1 225861324 7687283 complement(1359371..1359493) 1 NC_012469.1 hypothetical protein 1359493 7687283 SPT_1427 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742833.1 1359371 R 487213 CDS YP_002742834.1 225861325 7686490 complement(1359939..1360808) 1 NC_012469.1 identified by match to protein family HMM PF00230; glycerol facilitator-aquaporin gla (Aquaglyceroporin)(Glyceroaquaporin) 1360808 7686490 SPT_1428 Streptococcus pneumoniae Taiwan19F-14 glycerol facilitator-aquaporin gla (Aquaglyceroporin)(Glyceroaquaporin) YP_002742834.1 1359939 R 487213 CDS YP_002742835.1 225861326 7687009 complement(1361031..1361552) 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167; MucBP domain family 1361552 7687009 SPT_1429 Streptococcus pneumoniae Taiwan19F-14 MucBP domain family YP_002742835.1 1361031 R 487213 CDS YP_002742836.1 225861327 7685526 complement(1361524..1362615) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1362615 7685526 SPT_1430 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742836.1 1361524 R 487213 CDS YP_002742837.1 225861328 7686970 complement(1362726..1362980) 1 NC_012469.1 hypothetical protein 1362980 7686970 SPT_1431 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742837.1 1362726 R 487213 CDS YP_002742838.1 225861329 7687216 complement(1363320..1363853) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1363853 7687216 SPT_1432 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742838.1 1363320 R 487213 CDS YP_002742839.1 225861330 7686272 complement(1363840..1363974) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1363974 7686272 SPT_1433 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742839.1 1363840 R 487213 CDS YP_002742840.1 225861331 7686265 complement(1364022..1364165) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1364165 7686265 SPT_1434 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742840.1 1364022 R 487213 CDS YP_002742841.1 225861332 7685433 1364399..1366117 1 NC_012469.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 1366117 7685433 SPT_1435 Streptococcus pneumoniae Taiwan19F-14 phosphomannomutase YP_002742841.1 1364399 D 487213 CDS YP_002742842.1 225861333 7686415 1366228..1366575 1 NC_012469.1 identified by match to protein family HMM TIGR01295; bacterocin transport accessory protein 1366575 7686415 SPT_1436 Streptococcus pneumoniae Taiwan19F-14 bacterocin transport accessory protein YP_002742842.1 1366228 D 487213 CDS YP_002742843.1 225861334 7686912 complement(1366854..1367690) 1 NC_012469.1 identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport 1367690 7686912 SPT_1437 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - glutamine transport YP_002742843.1 1366854 R 487213 CDS YP_002742844.1 225861335 7686146 complement(1367703..1368332) 1 NC_012469.1 identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ 1368332 7686146 SPT_1438 Streptococcus pneumoniae Taiwan19F-14 glutamine transport ATP-binding protein GlnQ YP_002742844.1 1367703 R 487213 CDS YP_002742845.1 225861336 7686873 complement(1368342..1368983) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1368983 7686873 SPT_1439 Streptococcus pneumoniae Taiwan19F-14 amino acid ABC transporter permease YP_002742845.1 1368342 R 487213 CDS YP_002742846.1 225861337 7687169 complement(1369129..1370358) 1 NC_012469.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719; TPR domain protein 1370358 7687169 SPT_1440 Streptococcus pneumoniae Taiwan19F-14 TPR domain protein YP_002742846.1 1369129 R 487213 CDS YP_002742847.1 225861338 7685358 complement(1370348..1371514) 1 NC_012469.1 identified by match to protein family HMM PF01594; transport protein 1371514 7685358 SPT_1441 Streptococcus pneumoniae Taiwan19F-14 transport protein YP_002742847.1 1370348 R 487213 CDS YP_002742848.1 225861339 7686951 1371658..1372671 1 NC_012469.1 3-carboxymuconate cyclase 1372671 7686951 SPT_1442 Streptococcus pneumoniae Taiwan19F-14 3-carboxymuconate cyclase YP_002742848.1 1371658 D 487213 CDS YP_002742849.1 225861340 7686088 complement(1372716..1373135) 1 NC_012469.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 1373135 atpC 7686088 atpC Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit epsilon YP_002742849.1 1372716 R 487213 CDS YP_002742850.1 225861341 7686277 complement(1373146..1374552) 1 NC_012469.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1374552 atpD 7686277 atpD Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit beta YP_002742850.1 1373146 R 487213 CDS YP_002742851.1 225861342 7687228 complement(1374638..1375516) 1 NC_012469.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1375516 atpG 7687228 atpG Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit gamma YP_002742851.1 1374638 R 487213 CDS YP_002742852.1 225861343 7685872 complement(1375532..1377037) 1 NC_012469.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1377037 atpA 7685872 atpA Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit alpha YP_002742852.1 1375532 R 487213 CDS YP_002742853.1 225861344 7685972 complement(1377052..1377588) 1 NC_012469.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1377588 atpH 7685972 atpH Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit delta YP_002742853.1 1377052 R 487213 CDS YP_002742854.1 225861345 7685893 complement(1377588..1378082) 1 NC_012469.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1378082 atpF 7685893 atpF Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit B YP_002742854.1 1377588 R 487213 CDS YP_002742855.1 225861346 7686751 complement(1378096..1378812) 1 NC_012469.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1378812 atpB 7686751 atpB Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit A YP_002742855.1 1378096 R 487213 CDS YP_002742856.1 225861347 7685413 complement(1378847..1379047) 1 NC_012469.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1379047 7685413 SPT_1450 Streptococcus pneumoniae Taiwan19F-14 F0F1 ATP synthase subunit C YP_002742856.1 1378847 R 487213 CDS YP_002742857.1 225861348 7685757 complement(1380585..1380983) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 1380983 7685757 SPT_1453 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family protein YP_002742857.1 1380585 R 487213 CDS YP_002742858.1 225861349 7687257 1381111..1381254 1 NC_012469.1 chlorohydrolase 1381254 7687257 SPT_1454 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002742858.1 1381111 D 487213 CDS YP_002742859.1 225861350 7686708 complement(1381311..1381793) 1 NC_012469.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1381793 greA 7686708 greA Streptococcus pneumoniae Taiwan19F-14 transcription elongation factor GreA YP_002742859.1 1381311 R 487213 CDS YP_002742860.1 225861351 7685634 complement(1381864..1383519) 1 NC_012469.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; aminodeoxychorismate lyase 1383519 7685634 SPT_1456 Streptococcus pneumoniae Taiwan19F-14 aminodeoxychorismate lyase YP_002742860.1 1381864 R 487213 CDS YP_002742861.1 225861352 7685702 complement(1383600..1384094) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1384094 7685702 SPT_1457 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742861.1 1383600 R 487213 CDS YP_002742862.1 225861353 7685253 complement(1384091..1384555) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1384555 7685253 SPT_1458 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742862.1 1384091 R 487213 CDS YP_002742863.1 225861354 7685394 complement(1384565..1385899) 1 NC_012469.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1385899 murC 7685394 murC Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylmuramate--L-alanine ligase YP_002742863.1 1384565 R 487213 CDS YP_002742864.1 225861355 7686807 complement(1385910..1386527) 1 NC_012469.1 hypothetical protein 1386527 7686807 SPT_1460 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742864.1 1385910 R 487213 CDS YP_002742865.1 225861356 7685334 complement(1386575..1389673) 1 NC_012469.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455; Snf2 family protein 1389673 7685334 SPT_1461 Streptococcus pneumoniae Taiwan19F-14 Snf2 family protein YP_002742865.1 1386575 R 487213 CDS YP_002742866.1 225861357 7687355 complement(1389766..1390932) 1 NC_012469.1 identified by match to protein family HMM PF00155; putative aminotransferase B 1390932 7687355 SPT_1462 Streptococcus pneumoniae Taiwan19F-14 putative aminotransferase B YP_002742866.1 1389766 R 487213 CDS YP_002742867.1 225861358 7685619 complement(1390940..1392034) 1 NC_012469.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 1392034 7685619 SPT_1463 Streptococcus pneumoniae Taiwan19F-14 cystathionine gamma-synthase YP_002742867.1 1390940 R 487213 CDS YP_002742868.1 225861359 7687174 complement(1394045..1396006) 1 NC_012469.1 identified by match to protein family HMM PF00496; oligopeptide-binding protein AliB 1396006 7687174 SPT_1466 Streptococcus pneumoniae Taiwan19F-14 oligopeptide-binding protein AliB YP_002742868.1 1394045 R 487213 CDS YP_002742869.1 225861360 7687302 complement(1396207..1397829) 1 NC_012469.1 identified by match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide transporter 1397829 7687302 SPT_1467 Streptococcus pneumoniae Taiwan19F-14 polysaccharide transporter YP_002742869.1 1396207 R 487213 CDS YP_002742870.1 225861361 7686405 1397935..1399380 1 NC_012469.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1399380 7686405 SPT_1468 Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_002742870.1 1397935 D 487213 CDS YP_002742871.1 225861362 7686611 complement(1399426..1399620) 1 NC_012469.1 identified by match to protein family HMM PF05532; hypothetical protein 1399620 7686611 SPT_1469 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742871.1 1399426 R 487213 CDS YP_002742872.1 225861363 7685279 complement(1399721..1400317) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1400317 7685279 SPT_1470 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742872.1 1399721 R 487213 CDS YP_002742873.1 225861364 7687187 complement(1400354..1400866) 1 NC_012469.1 hypothetical protein 1400866 7687187 SPT_1471 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742873.1 1400354 R 487213 CDS YP_002742874.1 225861365 7686491 complement(1400953..1401888) 1 NC_012469.1 catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase 1401888 7686491 SPT_1472 Streptococcus pneumoniae Taiwan19F-14 putative manganese-dependent inorganic pyrophosphatase YP_002742874.1 1400953 R 487213 CDS YP_002742875.1 225861366 7686206 complement(1401959..1402258) 1 NC_012469.1 identified by match to protein family HMM PF01541; hypothetical protein 1402258 7686206 SPT_1473 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742875.1 1401959 R 487213 CDS YP_002742876.1 225861367 7685501 complement(1402248..1402997) 1 NC_012469.1 identified by match to protein family HMM PF05175; methyltransferase 1402997 7685501 SPT_1474 Streptococcus pneumoniae Taiwan19F-14 methyltransferase YP_002742876.1 1402248 R 487213 CDS YP_002742877.1 225861368 7686887 complement(1403051..1403437) 1 NC_012469.1 identified by match to protein family HMM PF00575; hypothetical protein 1403437 7686887 SPT_1475 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742877.1 1403051 R 487213 CDS YP_002742878.1 225861369 7686701 complement(1403412..1404812) 1 NC_012469.1 identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type 1404812 7686701 SPT_1476 Streptococcus pneumoniae Taiwan19F-14 Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_002742878.1 1403412 R 487213 CDS YP_002742879.1 225861370 7687299 complement(1405107..1405346) 1 NC_012469.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1405346 rpsR 7687299 rpsR Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S18 YP_002742879.1 1405107 R 487213 CDS YP_002742880.1 225861371 7687063 complement(1405378..1405848) 1 NC_012469.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1405848 7687063 SPT_1478 Streptococcus pneumoniae Taiwan19F-14 single-stranded DNA-binding protein YP_002742880.1 1405378 R 487213 CDS YP_002742881.1 225861372 7686307 complement(1405860..1406150) 1 NC_012469.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1406150 rpsF 7686307 rpsF Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S6 YP_002742881.1 1405860 R 487213 CDS YP_002742882.1 225861373 7685333 complement(1406303..1407646) 1 NC_012469.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1407646 asnC 7685333 asnC Streptococcus pneumoniae Taiwan19F-14 asparaginyl-tRNA synthetase YP_002742882.1 1406303 R 487213 CDS YP_002742883.1 225861374 7686142 complement(1407806..1408030) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; glyoxalase family protein, unverified point mutation 1408030 7686142 SPT_1481 Streptococcus pneumoniae Taiwan19F-14 glyoxalase family protein, unverified point mutation YP_002742883.1 1407806 R 487213 CDS YP_002742884.1 225861375 7686841 complement(1408023..1409210) 1 NC_012469.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1409210 7686841 SPT_1482 Streptococcus pneumoniae Taiwan19F-14 aspartate aminotransferase YP_002742884.1 1408023 R 487213 CDS YP_002742885.1 225861376 7687093 complement(1409207..1409695) 1 NC_012469.1 identified by match to protein family HMM PF03413; peptidase propeptide and ypeb domain protein 1409695 7687093 SPT_1483 Streptococcus pneumoniae Taiwan19F-14 peptidase propeptide and ypeb domain protein YP_002742885.1 1409207 R 487213 CDS YP_002742886.1 225861377 7686803 complement(1409762..1409878) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1409878 7686803 SPT_1484 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742886.1 1409762 R 487213 CDS YP_002742887.1 225861378 7685305 1410016..1410564 1 NC_012469.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358; oxidoreductase 1410564 7685305 SPT_1485 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase YP_002742887.1 1410016 D 487213 CDS YP_002742888.1 225861379 7685250 complement(1410801..1416422) 1 NC_012469.1 identified by match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; G5 domain family 1416422 7685250 SPT_1486 Streptococcus pneumoniae Taiwan19F-14 G5 domain family YP_002742888.1 1410801 R 487213 CDS YP_002742889.1 225861380 7685365 1416638..1418122 1 NC_012469.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280; M protein trans-acting positive transcriptional regulator 1418122 7685365 SPT_1487 Streptococcus pneumoniae Taiwan19F-14 M protein trans-acting positive transcriptional regulator YP_002742889.1 1416638 D 487213 CDS YP_002742890.1 225861381 7686541 complement(1418173..1418901) 1 NC_012469.1 identified by match to protein family HMM PF03883; hypothetical protein 1418901 7686541 SPT_1488 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742890.1 1418173 R 487213 CDS YP_002742891.1 225861382 7687300 complement(1418980..1419144) 1 NC_012469.1 hypothetical protein 1419144 7687300 SPT_1489 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742891.1 1418980 R 487213 CDS YP_002742892.1 225861383 7686796 complement(1419210..1420805) 1 NC_012469.1 hypothetical protein 1420805 7686796 SPT_1490 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742892.1 1419210 R 487213 CDS YP_002742893.1 225861384 7685290 complement(1420817..1421227) 1 NC_012469.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1421227 def2 7685290 def2 Streptococcus pneumoniae Taiwan19F-14 peptide deformylase YP_002742893.1 1420817 R 487213 CDS YP_002742894.1 225861385 7685421 complement(1421343..1422134) 1 NC_012469.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 1422134 7685421 SPT_1492 Streptococcus pneumoniae Taiwan19F-14 putative glutathione S-transferase YghU YP_002742894.1 1421343 R 487213 CDS YP_002742895.1 225861386 7685661 complement(1422147..1424843) 1 NC_012469.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; calcium-transporting ATPase 1 1424843 7685661 SPT_1493 Streptococcus pneumoniae Taiwan19F-14 calcium-transporting ATPase 1 YP_002742895.1 1422147 R 487213 CDS YP_002742896.1 225861387 7685316 1425147..1426331 1 NC_012469.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1426331 7685316 SPT_1494 Streptococcus pneumoniae Taiwan19F-14 cation efflux family protein YP_002742896.1 1425147 D 487213 CDS YP_002742897.1 225861388 7686812 complement(1426474..1428345) 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1428345 7686812 SPT_1495 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002742897.1 1426474 R 487213 CDS YP_002742898.1 225861389 7686950 complement(1428342..1429526) 1 NC_012469.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1429526 7686950 SPT_1496 Streptococcus pneumoniae Taiwan19F-14 tRNA CCA-pyrophosphorylase YP_002742898.1 1428342 R 487213 CDS YP_002742899.1 225861390 7685966 complement(1429538..1430305) 1 NC_012469.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1430305 dapB 7685966 dapB Streptococcus pneumoniae Taiwan19F-14 dihydrodipicolinate reductase YP_002742899.1 1429538 R 487213 CDS YP_002742900.1 225861391 7686902 complement(1430582..1431430) 1 NC_012469.1 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 1431430 7686902 SPT_1498 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742900.1 1430582 R 487213 CDS YP_002742901.1 225861392 7686409 complement(1431432..1431806) 1 NC_012469.1 identified by match to protein family HMM PF06619; hypothetical protein 1431806 7686409 SPT_1499 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742901.1 1431432 R 487213 CDS YP_002742902.1 225861393 7685729 complement(1431880..1433232) 1 NC_012469.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1433232 glmM 7685729 glmM Streptococcus pneumoniae Taiwan19F-14 phosphoglucosamine mutase YP_002742902.1 1431880 R 487213 CDS YP_002742903.1 225861394 7687242 complement(1433256..1434035) 1 NC_012469.1 identified by match to protein family HMM PF07949; lipoprotein, putative 1434035 7687242 SPT_1501 Streptococcus pneumoniae Taiwan19F-14 lipoprotein, putative YP_002742903.1 1433256 R 487213 CDS YP_002742904.1 225861395 7685452 complement(1434022..1434879) 1 NC_012469.1 identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein 1434879 7685452 SPT_1502 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742904.1 1434022 R 487213 CDS YP_002742905.1 225861396 7686835 1435015..1435983 1 NC_012469.1 identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992; thioredoxin reductase 1435983 7686835 SPT_1503 Streptococcus pneumoniae Taiwan19F-14 thioredoxin reductase YP_002742905.1 1435015 D 487213 CDS YP_002742906.1 225861397 7685418 complement(1436017..1436928) 1 NC_012469.1 identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 1436928 7685418 SPT_1504 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742906.1 1436017 R 487213 CDS YP_002742907.1 225861398 7685678 complement(1436925..1437902) 1 NC_012469.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; transporter 1437902 7685678 SPT_1505 Streptococcus pneumoniae Taiwan19F-14 transporter YP_002742907.1 1436925 R 487213 CDS YP_002742908.1 225861399 7686818 complement(1437899..1438789) 1 NC_012469.1 identified by match to protein family HMM PF03668; hypothetical protein 1438789 7686818 SPT_1506 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742908.1 1437899 R 487213 CDS YP_002742909.1 225861400 7685319 complement(1438841..1439221) 1 NC_012469.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP, putative 1439221 7685319 SPT_1507 Streptococcus pneumoniae Taiwan19F-14 endoribonuclease L-PSP, putative YP_002742909.1 1438841 R 487213 CDS YP_002742910.1 225861401 7686768 complement(1439232..1439819) 1 NC_012469.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1439819 engB 7686768 engB Streptococcus pneumoniae Taiwan19F-14 ribosome biogenesis GTP-binding protein YsxC YP_002742910.1 1439232 R 487213 CDS YP_002742911.1 225861402 7685876 complement(1439828..1441036) 1 NC_012469.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1441036 clpX 7685876 clpX Streptococcus pneumoniae Taiwan19F-14 ATP-dependent protease ATP-binding subunit ClpX YP_002742911.1 1439828 R 487213 CDS YP_002742912.1 225861403 7686549 complement(1441097..1441267) 1 NC_012469.1 hypothetical protein 1441267 7686549 SPT_1510 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742912.1 1441097 R 487213 CDS YP_002742913.1 225861404 7685846 complement(1441267..1441773) 1 NC_012469.1 identified by match to protein family HMM PF00186; dihydrofolate reductase 1441773 folA 7685846 folA Streptococcus pneumoniae Taiwan19F-14 dihydrofolate reductase YP_002742913.1 1441267 R 487213 CDS YP_002742914.1 225861405 7685517 complement(1441903..1442421) 1 NC_012469.1 identified by match to protein family HMM PF00210; DNA protection during starvation protein 1442421 7685517 SPT_1512 Streptococcus pneumoniae Taiwan19F-14 DNA protection during starvation protein YP_002742914.1 1441903 R 487213 CDS YP_002742915.1 225861406 7686966 complement(1442921..1444402) 1 NC_012469.1 identified by match to protein family HMM PF01183; match to protein family HMM PF01473; lysozyme 1444402 7686966 SPT_1513 Streptococcus pneumoniae Taiwan19F-14 lysozyme YP_002742915.1 1442921 R 487213 CDS YP_002742916.1 225861407 7687089 complement(1444473..1445231) 1 NC_012469.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1445231 tpiA 7687089 tpiA Streptococcus pneumoniae Taiwan19F-14 triosephosphate isomerase YP_002742916.1 1444473 R 487213 CDS YP_002742917.1 225861408 7686848 complement(1445329..1446006) 1 NC_012469.1 identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; DNA replication protein DnaD 1446006 7686848 SPT_1515 Streptococcus pneumoniae Taiwan19F-14 DNA replication protein DnaD YP_002742917.1 1445329 R 487213 CDS YP_002742918.1 225861409 7687135 complement(1446015..1446959) 1 NC_012469.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1446959 metA 7687135 metA Streptococcus pneumoniae Taiwan19F-14 homoserine O-succinyltransferase YP_002742918.1 1446015 R 487213 CDS YP_002742919.1 225861410 7685422 1446999..1447250 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1447250 7685422 SPT_1518 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742919.1 1446999 D 487213 CDS YP_002742920.1 225861411 7685354 complement(1447247..1447759) 1 NC_012469.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1447759 apt 7685354 apt Streptococcus pneumoniae Taiwan19F-14 adenine phosphoribosyltransferase YP_002742920.1 1447247 R 487213 CDS YP_002742921.1 225861412 7685644 complement(1447845..1448603) 1 NC_012469.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase 1448603 7685644 SPT_1519 Streptococcus pneumoniae Taiwan19F-14 SAM-dependent methyltransferase YP_002742921.1 1447845 R 487213 CDS YP_002742922.1 225861413 7686645 complement(1449104..1450234) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; multiple sugar-binding transport ATP-binding protein MsmK 1450234 7686645 SPT_1520 Streptococcus pneumoniae Taiwan19F-14 multiple sugar-binding transport ATP-binding protein MsmK YP_002742922.1 1449104 R 487213 CDS YP_002742923.1 225861414 7685579 complement(1450685..1451260) 1 NC_012469.1 identified by match to protein family HMM PF00857; isochorismatase 1451260 7685579 SPT_1522 Streptococcus pneumoniae Taiwan19F-14 isochorismatase YP_002742923.1 1450685 R 487213 CDS YP_002742924.1 225861415 7686158 complement(1451260..1452048) 1 NC_012469.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1452048 codY 7686158 codY Streptococcus pneumoniae Taiwan19F-14 transcriptional repressor CodY YP_002742924.1 1451260 R 487213 CDS YP_002742925.1 225861416 7687157 complement(1452313..1453887) 1 NC_012469.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; cold-shock DEAD box protein A 1453887 7687157 SPT_1524 Streptococcus pneumoniae Taiwan19F-14 cold-shock DEAD box protein A YP_002742925.1 1452313 R 487213 CDS YP_002742926.1 225861417 7686619 complement(1454086..1455312) 1 NC_012469.1 identified by match to protein family HMM PF07690; major facilitator:Oxalate:Formate Antiporter 1455312 7686619 SPT_1525 Streptococcus pneumoniae Taiwan19F-14 major facilitator:Oxalate:Formate Antiporter YP_002742926.1 1454086 R 487213 CDS YP_002742927.1 225861418 7687119 1455505..1456821 1 NC_012469.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1456821 7687119 SPT_1526 Streptococcus pneumoniae Taiwan19F-14 pyridine nucleotide-disulfide oxidoreductase YP_002742927.1 1455505 D 487213 CDS YP_002742928.1 225861419 7686855 1456920..1458263 1 NC_012469.1 identified by match to protein family HMM PF08245; match to protein family HMM PF08353; Mur ligase family protein 1458263 7686855 SPT_1527 Streptococcus pneumoniae Taiwan19F-14 Mur ligase family protein YP_002742928.1 1456920 D 487213 CDS YP_002742929.1 225861420 7687112 1458263..1459045 1 NC_012469.1 identified by match to protein family HMM PF07685; cobyric acid synthase 1459045 7687112 SPT_1528 Streptococcus pneumoniae Taiwan19F-14 cobyric acid synthase YP_002742929.1 1458263 D 487213 CDS YP_002742930.1 225861421 7686996 1459171..1460253 1 NC_012469.1 identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase (X-Pro dipeptidase) (Prolinedipeptidase) (Prolidase) (Imidodipeptidase) 1460253 7686996 SPT_1529 Streptococcus pneumoniae Taiwan19F-14 Xaa-Pro dipeptidase (X-Pro dipeptidase) (Prolinedipeptidase) (Prolidase) (Imidodipeptidase) YP_002742930.1 1459171 D 487213 CDS YP_002742931.1 225861422 7686253 1460303..1460449 1 NC_012469.1 acetyltransferase, gnat family 1460449 7686253 SPT_1530 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002742931.1 1460303 D 487213 CDS YP_002742932.1 225861423 7687234 complement(1460577..1460930) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1460930 7687234 SPT_1531 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742932.1 1460577 R 487213 CDS YP_002742933.1 225861424 7686300 complement(1460992..1461264) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1461264 7686300 SPT_1532 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742933.1 1460992 R 487213 CDS YP_002742934.1 225861425 7686097 complement(1461264..1461431) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1461431 7686097 SPT_1533 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742934.1 1461264 R 487213 CDS YP_002742935.1 225861426 7686907 complement(1461567..1461779) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1461779 7686907 SPT_1534 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002742935.1 1461567 R 487213 CDS YP_002742936.1 225861427 7685456 complement(1462010..1462471) 1 NC_012469.1 hypothetical protein 1462471 7685456 SPT_1535 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742936.1 1462010 R 487213 CDS YP_002742937.1 225861428 7685927 complement(1462449..1463222) 1 NC_012469.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1463222 7685927 SPT_1536 Streptococcus pneumoniae Taiwan19F-14 phosphomethylpyrimidine kinase YP_002742937.1 1462449 R 487213 CDS YP_002742938.1 225861429 7685493 complement(1463212..1463961) 1 NC_012469.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1463961 truA 7685493 truA Streptococcus pneumoniae Taiwan19F-14 tRNA pseudouridine synthase A YP_002742938.1 1463212 R 487213 CDS YP_002742939.1 225861430 7686881 1464140..1464301 1 NC_012469.1 hypothetical protein 1464301 7686881 SPT_1539 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742939.1 1464140 D 487213 CDS YP_002742940.1 225861431 7686589 complement(1464273..1465424) 1 NC_012469.1 identified by match to protein family HMM PF07690; major facilitator superfamily transporter 1465424 7686589 SPT_1538 Streptococcus pneumoniae Taiwan19F-14 major facilitator superfamily transporter YP_002742940.1 1464273 R 487213 CDS YP_002742941.1 225861432 7686344 1465396..1465512 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1465512 7686344 SPT_1540 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742941.1 1465396 D 487213 CDS YP_002742942.1 225861433 7686073 complement(1465664..1466293) 1 NC_012469.1 hypothetical protein 1466293 7686073 SPT_1541 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742942.1 1465664 R 487213 CDS YP_002742943.1 225861434 7686793 complement(1466296..1466634) 1 NC_012469.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA 1466634 phnA 7686793 phnA Streptococcus pneumoniae Taiwan19F-14 alkylphosphonate utilization operon protein PhnA YP_002742943.1 1466296 R 487213 CDS YP_002742944.1 225861435 7686478 complement(1466765..1467436) 1 NC_012469.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1467436 cmk 7686478 cmk Streptococcus pneumoniae Taiwan19F-14 cytidylate kinase YP_002742944.1 1466765 R 487213 CDS YP_002742945.1 225861436 7685955 complement(1467445..1467921) 1 NC_012469.1 hypothetical protein 1467921 7685955 SPT_1544 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742945.1 1467445 R 487213 CDS YP_002742946.1 225861437 7687143 1467967..1468179 1 NC_012469.1 ferredoxin 1468179 7687143 SPT_1545 Streptococcus pneumoniae Taiwan19F-14 ferredoxin YP_002742946.1 1467967 D 487213 CDS YP_002742947.1 225861438 7686783 complement(1468230..1469195) 1 NC_012469.1 identified by match to protein family HMM PF00535; bactoprenol glucosyl transferase 1469195 7686783 SPT_1546 Streptococcus pneumoniae Taiwan19F-14 bactoprenol glucosyl transferase YP_002742947.1 1468230 R 487213 CDS YP_002742948.1 225861439 7685643 complement(1469197..1470216) 1 NC_012469.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 1470216 galE1 7685643 galE1 Streptococcus pneumoniae Taiwan19F-14 UDP-glucose 4-epimerase YP_002742948.1 1469197 R 487213 CDS YP_002742949.1 225861440 7686758 complement(1470517..1471620) 1 NC_012469.1 identified by match to protein family HMM PF01266; FAD dependent oxidoreductase 1471620 7686758 SPT_1549 Streptococcus pneumoniae Taiwan19F-14 FAD dependent oxidoreductase YP_002742949.1 1470517 R 487213 CDS YP_002742950.1 225861441 7687028 complement(1471637..1472434) 1 NC_012469.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 1472434 7687028 SPT_1550 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742950.1 1471637 R 487213 CDS YP_002742951.1 225861442 7687083 complement(1472421..1473098) 1 NC_012469.1 identified by match to protein family HMM PF04816; Bcl-2 family protein 1473098 7687083 SPT_1551 Streptococcus pneumoniae Taiwan19F-14 Bcl-2 family protein YP_002742951.1 1472421 R 487213 CDS YP_002742952.1 225861443 7686397 1473647..1473823 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1473823 7686397 SPT_1552 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742952.1 1473647 D 487213 CDS YP_002742953.1 225861444 7685772 1474024..1474266 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1474266 7685772 SPT_1553 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742953.1 1474024 D 487213 CDS YP_002742954.1 225861445 7686280 complement(1474718..1475989) 1 NC_012469.1 identified by match to protein family HMM PF00665; IS3-Spn1, transposase 1475989 7686280 SPT_1554 Streptococcus pneumoniae Taiwan19F-14 IS3-Spn1, transposase YP_002742954.1 1474718 R 487213 CDS YP_002742955.1 225861446 7686564 complement(1476362..1478332) 1 NC_012469.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1478332 tkt1 7686564 tkt1 Streptococcus pneumoniae Taiwan19F-14 transketolase YP_002742955.1 1476362 R 487213 CDS YP_002742956.1 225861447 7686489 complement(1478369..1479064) 1 NC_012469.1 identified by match to protein family HMM PF00834; allulose-6-phosphate 3-epimerase 1479064 7686489 SPT_1556 Streptococcus pneumoniae Taiwan19F-14 allulose-6-phosphate 3-epimerase YP_002742956.1 1478369 R 487213 CDS YP_002742957.1 225861448 7686526 complement(1479075..1480160) 1 NC_012469.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system, IIC component 1480160 7686526 SPT_1557 Streptococcus pneumoniae Taiwan19F-14 PTS system, IIC component YP_002742957.1 1479075 R 487213 CDS YP_002742958.1 225861449 7686102 complement(1480525..1480974) 1 NC_012469.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848; PTS system, IIA component 1480974 7686102 SPT_1559 Streptococcus pneumoniae Taiwan19F-14 PTS system, IIA component YP_002742958.1 1480525 R 487213 CDS YP_002742959.1 225861450 7687023 complement(1480952..1481380) 1 NC_012469.1 identified by match to protein family HMM PF00359; PTS system, nitrogen regulatory component IIA, putative 1481380 7687023 SPT_1560 Streptococcus pneumoniae Taiwan19F-14 PTS system, nitrogen regulatory component IIA, putative YP_002742959.1 1480952 R 487213 CDS YP_002742960.1 225861451 7686387 complement(1481373..1482836) 1 NC_012469.1 identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; putative transcription antiterminator BglG family protein 1482836 7686387 SPT_1561 Streptococcus pneumoniae Taiwan19F-14 putative transcription antiterminator BglG family protein YP_002742960.1 1481373 R 487213 CDS YP_002742961.1 225861452 7687364 complement(1483365..1485701) 1 NC_012469.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; cation-transporting ATPase, E1-E2 family 1485701 7687364 SPT_1562 Streptococcus pneumoniae Taiwan19F-14 cation-transporting ATPase, E1-E2 family YP_002742961.1 1483365 R 487213 CDS YP_002742962.1 225861453 7687269 1485834..1486583 1 NC_012469.1 identified by match to protein family HMM PF01553; acyltransferase family protein 1486583 7687269 SPT_1563 Streptococcus pneumoniae Taiwan19F-14 acyltransferase family protein YP_002742962.1 1485834 D 487213 CDS YP_002742963.1 225861454 7685215 complement(1486876..1487490) 1 NC_012469.1 identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779; CadD 1487490 7685215 SPT_1564 Streptococcus pneumoniae Taiwan19F-14 CadD YP_002742963.1 1486876 R 487213 CDS YP_002742964.1 225861455 7685430 complement(1488307..1488576) 1 NC_012469.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1488576 rpsO 7685430 rpsO Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S15 YP_002742964.1 1488307 R 487213 CDS YP_002742965.1 225861456 7687170 complement(1488717..1489346) 1 NC_012469.1 YwnB 1489346 7687170 SPT_1566 Streptococcus pneumoniae Taiwan19F-14 YwnB YP_002742965.1 1488717 R 487213 CDS YP_002742966.1 225861457 7685902 1489409..1489531 1 NC_012469.1 hypothetical protein 1489531 7685902 SPT_1567 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742966.1 1489409 D 487213 CDS YP_002742967.1 225861458 7686180 1490362..1490538 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1490538 7686180 SPT_1569 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742967.1 1490362 D 487213 CDS YP_002742968.1 225861459 7685795 1490596..1492539 1 NC_012469.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1492539 thrS 7685795 thrS Streptococcus pneumoniae Taiwan19F-14 threonyl-tRNA synthetase YP_002742968.1 1490596 D 487213 CDS YP_002742969.1 225861460 7685759 complement(1492588..1493562) 1 NC_012469.1 identified by match to protein family HMM PF02518; histidine kinase 1493562 7685759 SPT_1571 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002742969.1 1492588 R 487213 CDS YP_002742970.1 225861461 7685761 complement(1493555..1494232) 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 1494232 7685761 SPT_1572 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002742970.1 1493555 R 487213 CDS YP_002742971.1 225861462 7687273 1494388..1495461 1 NC_012469.1 hypothetical protein 1495461 7687273 SPT_1573 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742971.1 1494388 D 487213 CDS YP_002742972.1 225861463 7685384 complement(1495552..1495854) 1 NC_012469.1 hypothetical protein 1495854 7685384 SPT_1574 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742972.1 1495552 R 487213 CDS YP_002742973.1 225861464 7686053 complement(1495922..1496359) 1 NC_012469.1 identified by match to protein family HMM PF02082; Rrf2 family protein 1496359 7686053 SPT_1575 Streptococcus pneumoniae Taiwan19F-14 Rrf2 family protein YP_002742973.1 1495922 R 487213 CDS YP_002742974.1 225861465 7687203 complement(1496435..1497277) 1 NC_012469.1 identified by match to protein family HMM PF00149; metallophosphoesterase 1497277 7687203 SPT_1576 Streptococcus pneumoniae Taiwan19F-14 metallophosphoesterase YP_002742974.1 1496435 R 487213 CDS YP_002742975.1 225861466 7686680 1497389..1498039 1 NC_012469.1 identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron-dependent transcriptional regulator 1498039 7686680 SPT_1577 Streptococcus pneumoniae Taiwan19F-14 iron-dependent transcriptional regulator YP_002742975.1 1497389 D 487213 CDS YP_002742976.1 225861467 7686861 1498020..1498211 1 NC_012469.1 hypothetical protein 1498211 7686861 SPT_1578 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742976.1 1498020 D 487213 CDS YP_002742977.1 225861468 7687136 1498237..1498755 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1498755 7687136 SPT_1579 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742977.1 1498237 D 487213 CDS YP_002742978.1 225861469 7687132 1498752..1498883 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1498883 7687132 SPT_1580 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742978.1 1498752 D 487213 CDS YP_002742979.1 225861470 7686908 complement(1499276..1500622) 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 1500622 7686908 SPT_1581 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002742979.1 1499276 R 487213 CDS YP_002742980.1 225861471 7686041 1500824..1501135 1 NC_012469.1 hypothetical protein 1501135 7686041 SPT_1582 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742980.1 1500824 D 487213 CDS YP_002742981.1 225861472 7686472 1501409..1501570 1 NC_012469.1 hypothetical protein 1501570 7686472 SPT_1583 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742981.1 1501409 D 487213 CDS YP_002742982.1 225861473 7687275 complement(1501609..1502052) 1 NC_012469.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1502052 dtd 7687275 dtd Streptococcus pneumoniae Taiwan19F-14 D-tyrosyl-tRNA(Tyr) deacylase YP_002742982.1 1501609 R 487213 CDS YP_002742983.1 225861474 7686828 complement(1502082..1504304) 1 NC_012469.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase 1504304 spoT 7686828 spoT Streptococcus pneumoniae Taiwan19F-14 guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase YP_002742983.1 1502082 R 487213 CDS YP_002742984.1 225861475 7685408 1505298..1505927 1 NC_012469.1 identified by match to protein family HMM PF00753; metallo-beta-lactamase superfamily protein 1505927 7685408 SPT_1586 Streptococcus pneumoniae Taiwan19F-14 metallo-beta-lactamase superfamily protein YP_002742984.1 1505298 D 487213 CDS YP_002742985.1 225861476 7685514 complement(1506050..1507942) 1 NC_012469.1 identified by match to protein family HMM PF01431; match to protein family HMM PF05649; endopeptidase O 1507942 7685514 SPT_1587 Streptococcus pneumoniae Taiwan19F-14 endopeptidase O YP_002742985.1 1506050 R 487213 CDS YP_002742986.1 225861477 7685352 1508233..1508955 1 NC_012469.1 identified by match to protein family HMM PF00005; manganese transport system ATP-binding protein MntA 1508955 7685352 SPT_1588 Streptococcus pneumoniae Taiwan19F-14 manganese transport system ATP-binding protein MntA YP_002742986.1 1508233 D 487213 CDS YP_002742987.1 225861478 7686376 1508952..1509800 1 NC_012469.1 identified by match to protein family HMM PF00950; manganese transport system membrane protein MntB 1509800 7686376 SPT_1589 Streptococcus pneumoniae Taiwan19F-14 manganese transport system membrane protein MntB YP_002742987.1 1508952 D 487213 CDS YP_002742988.1 225861479 7685851 1509832..1510761 1 NC_012469.1 identified by match to protein family HMM PF01297; manganese ABC transporter substrate-binding lipoprotein (Adhesin B) (Saliva-binding protein) 1510761 7685851 SPT_1590 Streptococcus pneumoniae Taiwan19F-14 manganese ABC transporter substrate-binding lipoprotein (Adhesin B) (Saliva-binding protein) YP_002742988.1 1509832 D 487213 CDS YP_002742989.1 225861480 7685991 1510884..1511375 1 NC_012469.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1511375 tpx 7685991 tpx Streptococcus pneumoniae Taiwan19F-14 thiol peroxidase YP_002742989.1 1510884 D 487213 CDS YP_002742990.1 225861481 7687259 complement(1511471..1514179) 1 NC_012469.1 identified by match to protein family HMM PF02687; efflux ABC transporter, permease protein 1514179 7687259 SPT_1592 Streptococcus pneumoniae Taiwan19F-14 efflux ABC transporter, permease protein YP_002742990.1 1511471 R 487213 CDS YP_002742991.1 225861482 7685735 complement(1514181..1514882) 1 NC_012469.1 identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 1514882 7685735 SPT_1593 Streptococcus pneumoniae Taiwan19F-14 macrolide export ATP-binding/permease protein MacB YP_002742991.1 1514181 R 487213 CDS YP_002742992.1 225861483 7685251 complement(1515132..1517543) 1 NC_012469.1 alpha-fucosidase 1517543 7685251 SPT_1594 Streptococcus pneumoniae Taiwan19F-14 alpha-fucosidase YP_002742992.1 1515132 R 487213 CDS YP_002742993.1 225861484 7685918 complement(1517596..1518288) 1 NC_012469.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1518288 gpmA 7685918 gpmA Streptococcus pneumoniae Taiwan19F-14 phosphoglyceromutase YP_002742993.1 1517596 R 487213 CDS YP_002742994.1 225861485 7686084 complement(1518339..1518527) 1 NC_012469.1 hypothetical protein 1518527 7686084 SPT_1596 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742994.1 1518339 R 487213 CDS YP_002742995.1 225861486 7685440 complement(1518823..1519185) 1 NC_012469.1 integral membrane protein 1519185 7685440 SPT_1597 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002742995.1 1518823 R 487213 CDS YP_002742996.1 225861487 7687113 complement(1519593..1522385) 1 NC_012469.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1522385 ileS 7687113 ileS Streptococcus pneumoniae Taiwan19F-14 isoleucyl-tRNA synthetase YP_002742996.1 1519593 R 487213 CDS YP_002742997.1 225861488 7686925 complement(1522638..1522754) 1 NC_012469.1 hypothetical protein 1522754 7686925 SPT_1599 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002742997.1 1522638 R 487213 CDS YP_002742998.1 225861489 7687366 complement(1522733..1523521) 1 NC_012469.1 identified by match to protein family HMM PF05103; cell-division initiation protein 1523521 7687366 SPT_1600 Streptococcus pneumoniae Taiwan19F-14 cell-division initiation protein YP_002742998.1 1522733 R 487213 CDS YP_002742999.1 225861490 7687042 complement(1523530..1524315) 1 NC_012469.1 identified by match to protein family HMM PF01479; YlmH protein 1524315 7687042 SPT_1601 Streptococcus pneumoniae Taiwan19F-14 YlmH protein YP_002742999.1 1523530 R 487213 CDS YP_002743000.1 225861491 7686121 complement(1524312..1524575) 1 NC_012469.1 identified by match to protein family HMM PF02325; yggt family, putative 1524575 7686121 SPT_1602 Streptococcus pneumoniae Taiwan19F-14 yggt family, putative YP_002743000.1 1524312 R 487213 CDS YP_002743001.1 225861492 7686230 complement(1524575..1525114) 1 NC_012469.1 identified by match to protein family HMM PF04472; YlmF protein 1525114 7686230 SPT_1603 Streptococcus pneumoniae Taiwan19F-14 YlmF protein YP_002743001.1 1524575 R 487213 CDS YP_002743002.1 225861493 7685696 complement(1525124..1525795) 1 NC_012469.1 identified by match to protein family HMM TIGR00044; pyridoxal phosphate enzyme, YggS family 1525795 7685696 SPT_1604 Streptococcus pneumoniae Taiwan19F-14 pyridoxal phosphate enzyme, YggS family YP_002743002.1 1525124 R 487213 CDS YP_002743003.1 225861494 7687248 complement(1525800..1527059) 1 NC_012469.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1527059 ftsZ 7687248 ftsZ Streptococcus pneumoniae Taiwan19F-14 cell division protein FtsZ YP_002743003.1 1525800 R 487213 CDS YP_002743004.1 225861495 7685747 complement(1527076..1528449) 1 NC_012469.1 identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1528449 ftsA 7685747 ftsA Streptococcus pneumoniae Taiwan19F-14 cell division protein FtsA YP_002743004.1 1527076 R 487213 CDS YP_002743005.1 225861496 7686388 complement(1528669..1529373) 1 NC_012469.1 identified by match to protein family HMM TIGR02206; hypothetical protein 1529373 7686388 SPT_1607 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743005.1 1528669 R 487213 CDS YP_002743006.1 225861497 7685373 complement(1529464..1530075) 1 NC_012469.1 identified by match to protein family HMM PF00293; MutT/nudix family protein 1530075 7685373 SPT_1608 Streptococcus pneumoniae Taiwan19F-14 MutT/nudix family protein YP_002743006.1 1529464 R 487213 CDS YP_002743007.1 225861498 7686112 complement(1530062..1531435) 1 NC_012469.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 1531435 7686112 SPT_1609 Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase YP_002743007.1 1530062 R 487213 CDS YP_002743008.1 225861499 7686678 complement(1531519..1532562) 1 NC_012469.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1532562 ddl 7686678 ddl Streptococcus pneumoniae Taiwan19F-14 D-alanyl-alanine synthetase A YP_002743008.1 1531519 R 487213 CDS YP_002743009.1 225861500 7686661 complement(1532738..1533334) 1 NC_012469.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1533334 recR 7686661 recR Streptococcus pneumoniae Taiwan19F-14 recombination protein RecR YP_002743009.1 1532738 R 487213 CDS YP_002743010.1 225861501 7687404 complement(1533345..1535387) 1 NC_012469.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 2B 1535387 7687404 SPT_1612 Streptococcus pneumoniae Taiwan19F-14 penicillin-binding protein 2B YP_002743010.1 1533345 R 487213 CDS YP_002743011.1 225861502 7686157 1535596..1536447 1 NC_012469.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; transcriptional regulator, RpiR family 1536447 7686157 SPT_1613 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, RpiR family YP_002743011.1 1535596 D 487213 CDS YP_002743012.1 225861503 7686090 complement(1536463..1537347) 1 NC_012469.1 identified by match to protein family HMM PF00480; glucokinase 1537347 7686090 SPT_1614 Streptococcus pneumoniae Taiwan19F-14 glucokinase YP_002743012.1 1536463 R 487213 CDS YP_002743013.1 225861504 7686621 complement(1537365..1538282) 1 NC_012469.1 identified by match to protein family HMM PF00701; N-acetylneuraminate lyase 1538282 7686621 SPT_1615 Streptococcus pneumoniae Taiwan19F-14 N-acetylneuraminate lyase YP_002743013.1 1537365 R 487213 CDS YP_002743014.1 225861505 7687036 complement(1539387..1539695) 1 NC_012469.1 hypothetical protein 1539695 7687036 SPT_1617 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743014.1 1539387 R 487213 CDS YP_002743015.1 225861506 7685848 complement(1539837..1540289) 1 NC_012469.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1540289 7685848 SPT_1618 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743015.1 1539837 R 487213 CDS YP_002743016.1 225861507 7685428 complement(1540562..1541401) 1 NC_012469.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1541401 7685428 SPT_1619 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter permease YP_002743016.1 1540562 R 487213 CDS YP_002743017.1 225861508 7685905 complement(1541417..1542304) 1 NC_012469.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1542304 7685905 SPT_1620 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter permease YP_002743017.1 1541417 R 487213 CDS YP_002743018.1 225861509 7685451 complement(1542536..1543864) 1 NC_012469.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1543864 7685451 SPT_1621 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter substrate-binding protein YP_002743018.1 1542536 R 487213 CDS YP_002743019.1 225861510 7686856 complement(1543989..1545506) 1 NC_012469.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; pts system maltose- and glucose-specific eiicb component 1545506 7686856 SPT_1622 Streptococcus pneumoniae Taiwan19F-14 pts system maltose- and glucose-specific eiicb component YP_002743019.1 1543989 R 487213 CDS YP_002743020.1 225861511 7687095 complement(1545525..1546223) 1 NC_012469.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1546223 7687095 SPT_1623 Streptococcus pneumoniae Taiwan19F-14 N-acetylmannosamine-6-phosphate 2-epimerase YP_002743020.1 1545525 R 487213 CDS YP_002743021.1 225861512 7685481 complement(1546397..1547500) 1 NC_012469.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447; putative oxidoreductase YjhC 1547500 7685481 SPT_1624 Streptococcus pneumoniae Taiwan19F-14 putative oxidoreductase YjhC YP_002743021.1 1546397 R 487213 CDS YP_002743022.1 225861513 7687190 complement(1547513..1549606) 1 NC_012469.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; sialidase B (Neuraminidase B) 1549606 7687190 SPT_1625 Streptococcus pneumoniae Taiwan19F-14 sialidase B (Neuraminidase B) YP_002743022.1 1547513 R 487213 CDS YP_002743023.1 225861514 7686188 complement(1549624..1550457) 1 NC_012469.1 identified by match to protein family HMM PF00528; ABC transporter permease 1550457 7686188 SPT_1626 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002743023.1 1549624 R 487213 CDS YP_002743024.1 225861515 7685457 complement(1550457..1551341) 1 NC_012469.1 identified by match to protein family HMM PF00528; ABC transporter permease 1551341 7685457 SPT_1627 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002743024.1 1550457 R 487213 CDS YP_002743025.1 225861516 7686224 complement(1551420..1552757) 1 NC_012469.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1552757 7686224 SPT_1628 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter substrate-binding protein YP_002743025.1 1551420 R 487213 CDS YP_002743026.1 225861517 7686134 complement(1552776..1553228) 1 NC_012469.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein 1553228 7686134 SPT_1629 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743026.1 1552776 R 487213 CDS YP_002743027.1 225861518 7685395 complement(1554242..1557118) 1 NC_012469.1 identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167; neuraminidase 1557118 7685395 SPT_1630 Streptococcus pneumoniae Taiwan19F-14 neuraminidase YP_002743027.1 1554242 R 487213 CDS YP_002743028.1 225861519 7685949 complement(1557475..1557702) 1 NC_012469.1 hypothetical protein 1557702 7685949 SPT_1631 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743028.1 1557475 R 487213 CDS YP_002743029.1 225861520 7686773 1558100..1558591 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1558591 7686773 SPT_1632 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743029.1 1558100 D 487213 CDS YP_002743030.1 225861521 7687332 complement(1560210..1562225) 1 NC_012469.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1562225 recG 7687332 recG Streptococcus pneumoniae Taiwan19F-14 ATP-dependent DNA helicase RecG YP_002743030.1 1560210 R 487213 CDS YP_002743031.1 225861522 7685534 complement(1562244..1563347) 1 NC_012469.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1563347 alr 7685534 alr Streptococcus pneumoniae Taiwan19F-14 alanine racemase YP_002743031.1 1562244 R 487213 CDS YP_002743032.1 225861523 7685677 complement(1563337..1563699) 1 NC_012469.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 1563699 acpS 7685677 acpS Streptococcus pneumoniae Taiwan19F-14 4'-phosphopantetheinyl transferase YP_002743032.1 1563337 R 487213 CDS YP_002743033.1 225861524 7685462 complement(1563744..1564775) 1 NC_012469.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1564775 7685462 SPT_1638 Streptococcus pneumoniae Taiwan19F-14 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002743033.1 1563744 R 487213 CDS YP_002743034.1 225861525 7685744 complement(1564777..1565808) 1 NC_012469.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 1565808 7685744 SPT_1639 Streptococcus pneumoniae Taiwan19F-14 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002743034.1 1564777 R 487213 CDS YP_002743035.1 225861526 7686493 complement(1565889..1568402) 1 NC_012469.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1568402 secA 7686493 secA Streptococcus pneumoniae Taiwan19F-14 preprotein translocase subunit SecA YP_002743035.1 1565889 R 487213 CDS YP_002743036.1 225861527 7685274 complement(1568548..1568835) 1 NC_012469.1 hypothetical protein 1568835 7685274 SPT_1641 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743036.1 1568548 R 487213 CDS YP_002743037.1 225861528 7685688 complement(1568846..1569496) 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1569496 7685688 SPT_1642 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002743037.1 1568846 R 487213 CDS YP_002743038.1 225861529 7686498 complement(1569500..1570141) 1 NC_012469.1 hypothetical protein 1570141 7686498 SPT_1643 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743038.1 1569500 R 487213 CDS YP_002743039.1 225861530 7687097 complement(1570134..1570925) 1 NC_012469.1 hypothetical protein 1570925 7687097 SPT_1644 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743039.1 1570134 R 487213 CDS YP_002743040.1 225861531 7687286 complement(1571110..1571448) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1571448 7687286 SPT_1645 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743040.1 1571110 R 487213 CDS YP_002743041.1 225861532 7686479 complement(1571585..1571932) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1571932 7686479 SPT_1646 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743041.1 1571585 R 487213 CDS YP_002743042.1 225861533 7685988 complement(1572011..1573321) 1 NC_012469.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1573321 engA 7685988 engA Streptococcus pneumoniae Taiwan19F-14 GTP-binding protein EngA YP_002743042.1 1572011 R 487213 CDS YP_002743043.1 225861534 7685763 complement(1573335..1574048) 1 NC_012469.1 identified by match to protein family HMM PF00881; nitroreductase family protein 1574048 7685763 SPT_1648 Streptococcus pneumoniae Taiwan19F-14 nitroreductase family protein YP_002743043.1 1573335 R 487213 CDS YP_002743044.1 225861535 7685230 complement(1574045..1574941) 1 NC_012469.1 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1574941 7685230 SPT_1649 Streptococcus pneumoniae Taiwan19F-14 primosomal protein DnaI YP_002743044.1 1574045 R 487213 CDS YP_002743045.1 225861536 7686407 complement(1574942..1576111) 1 NC_012469.1 identified by match to protein family HMM PF07261; replication initiation and membrane attachment protein 1576111 7686407 SPT_1650 Streptococcus pneumoniae Taiwan19F-14 replication initiation and membrane attachment protein YP_002743045.1 1574942 R 487213 CDS YP_002743046.1 225861537 7685412 complement(1576112..1576585) 1 NC_012469.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 1576585 nrdR 7685412 nrdR Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator NrdR YP_002743046.1 1576112 R 487213 CDS YP_002743047.1 225861538 7685960 1576725..1577090 1 NC_012469.1 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1577090 7685960 SPT_1652 Streptococcus pneumoniae Taiwan19F-14 GntR family transcriptional regulator YP_002743047.1 1576725 D 487213 CDS YP_002743048.1 225861539 7686212 1577095..1577790 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1577790 7686212 SPT_1653 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002743048.1 1577095 D 487213 CDS YP_002743049.1 225861540 7687314 1577807..1578574 1 NC_012469.1 hypothetical protein 1578574 7687314 SPT_1654 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743049.1 1577807 D 487213 CDS YP_002743050.1 225861541 7686734 complement(1578927..1580126) 1 NC_012469.1 Na+ ABC transporter permease 1580126 7686734 SPT_1655 Streptococcus pneumoniae Taiwan19F-14 Na+ ABC transporter permease YP_002743050.1 1578927 R 487213 CDS YP_002743051.1 225861542 7685263 complement(1580123..1581016) 1 NC_012469.1 identified by match to protein family HMM PF00005; Na+ ABC transporter ATP-binding protein 1581016 7685263 SPT_1656 Streptococcus pneumoniae Taiwan19F-14 Na+ ABC transporter ATP-binding protein YP_002743051.1 1580123 R 487213 CDS YP_002743052.1 225861543 7686385 1581139..1581330 1 NC_012469.1 chlorohydrolase 1581330 7686385 SPT_1657 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002743052.1 1581139 D 487213 CDS YP_002743053.1 225861544 7685727 1582332..1582949 1 NC_012469.1 identified by match to protein family HMM PF09335; hypothetical protein 1582949 7685727 SPT_1658 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743053.1 1582332 D 487213 CDS YP_002743054.1 225861545 7687319 complement(1583269..1584156) 1 NC_012469.1 identified by match to protein family HMM PF00480; fructokinase 1584156 7687319 SPT_1659 Streptococcus pneumoniae Taiwan19F-14 fructokinase YP_002743054.1 1583269 R 487213 CDS YP_002743055.1 225861546 7687402 complement(1584305..1586188) 1 NC_012469.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996; pts system, sucrose-specific iibc component 1586188 7687402 SPT_1660 Streptococcus pneumoniae Taiwan19F-14 pts system, sucrose-specific iibc component YP_002743055.1 1584305 R 487213 CDS YP_002743056.1 225861547 7686677 1586380..1586496 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1586496 7686677 SPT_1661 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743056.1 1586380 D 487213 CDS YP_002743057.1 225861548 7686151 1586565..1588019 1 NC_012469.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase (Sucrase) (Invertase) 1588019 7686151 SPT_1662 Streptococcus pneumoniae Taiwan19F-14 sucrose-6-phosphate hydrolase (Sucrase) (Invertase) YP_002743057.1 1586565 D 487213 CDS YP_002743058.1 225861549 7686442 1588000..1588965 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose operon repressor (Scr operon regulatory protein) 1588965 7686442 SPT_1663 Streptococcus pneumoniae Taiwan19F-14 sucrose operon repressor (Scr operon regulatory protein) YP_002743058.1 1588000 D 487213 CDS YP_002743059.1 225861550 7685311 complement(1589000..1590274) 1 NC_012469.1 identified by match to protein family HMM TIGR00532; hydroxymethylglutaryl-CoA reductase, degradative 1590274 7685311 SPT_1664 Streptococcus pneumoniae Taiwan19F-14 hydroxymethylglutaryl-CoA reductase, degradative YP_002743059.1 1589000 R 487213 CDS YP_002743060.1 225861551 7686772 complement(1590274..1591470) 1 NC_012469.1 identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835; hydroxymethylglutaryl-CoA synthase 1591470 7686772 SPT_1665 Streptococcus pneumoniae Taiwan19F-14 hydroxymethylglutaryl-CoA synthase YP_002743060.1 1590274 R 487213 CDS YP_002743061.1 225861552 7685423 complement(1592391..1592840) 1 NC_012469.1 hypothetical protein 1592840 7685423 SPT_1668 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743061.1 1592391 R 487213 CDS YP_002743062.1 225861553 7685725 complement(1592842..1593600) 1 NC_012469.1 identified by match to protein family HMM PF06738; hypothetical protein 1593600 7685725 SPT_1669 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743062.1 1592842 R 487213 CDS YP_002743063.1 225861554 7686287 complement(1593715..1595694) 1 NC_012469.1 identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793; Stk1 1595694 7686287 SPT_1670 Streptococcus pneumoniae Taiwan19F-14 Stk1 YP_002743063.1 1593715 R 487213 CDS YP_002743064.1 225861555 7686528 complement(1595691..1596431) 1 NC_012469.1 identified by match to protein family HMM PF00481; protein phosphatase PrpC 1596431 7686528 SPT_1671 Streptococcus pneumoniae Taiwan19F-14 protein phosphatase PrpC YP_002743064.1 1595691 R 487213 CDS YP_002743065.1 225861556 7686383 complement(1596446..1597759) 1 NC_012469.1 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; ribosomal RNA small subunit methyltransferase B 1597759 sun 7686383 sun Streptococcus pneumoniae Taiwan19F-14 ribosomal RNA small subunit methyltransferase B YP_002743065.1 1596446 R 487213 CDS YP_002743066.1 225861557 7685981 complement(1597752..1598687) 1 NC_012469.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1598687 fmt 7685981 fmt Streptococcus pneumoniae Taiwan19F-14 methionyl-tRNA formyltransferase YP_002743066.1 1597752 R 487213 CDS YP_002743067.1 225861558 7685536 complement(1598700..1601096) 1 NC_012469.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1601096 7685536 SPT_1674 Streptococcus pneumoniae Taiwan19F-14 primosome assembly protein PriA YP_002743067.1 1598700 R 487213 CDS YP_002743068.1 225861559 7686403 complement(1601162..1601476) 1 NC_012469.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1601476 7686403 SPT_1675 Streptococcus pneumoniae Taiwan19F-14 DNA-directed RNA polymerase subunit omega YP_002743068.1 1601162 R 487213 CDS YP_002743069.1 225861560 7685774 complement(1601501..1602127) 1 NC_012469.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1602127 gmk 7685774 gmk Streptococcus pneumoniae Taiwan19F-14 guanylate kinase YP_002743069.1 1601501 R 487213 CDS YP_002743070.1 225861561 7686378 complement(1602257..1603870) 1 NC_012469.1 identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319; hypothetical protein 1603870 7686378 SPT_1677 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743070.1 1602257 R 487213 CDS YP_002743071.1 225861562 7687356 complement(1604139..1604318) 1 NC_012469.1 prevent-host-death family protein 1604318 7687356 SPT_1678 Streptococcus pneumoniae Taiwan19F-14 prevent-host-death family protein YP_002743071.1 1604139 R 487213 CDS YP_002743072.1 225861563 7687247 1604478..1605824 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 1605824 7687247 SPT_1679 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002743072.1 1604478 D 487213 CDS YP_002743073.1 225861564 7686802 complement(1606315..1607412) 1 NC_012469.1 identified by match to protein family HMM PF05636; hypothetical protein 1607412 7686802 SPT_1680 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743073.1 1606315 R 487213 CDS YP_002743074.1 225861565 7685777 complement(1607422..1608168) 1 NC_012469.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase 1608168 7685777 SPT_1681 Streptococcus pneumoniae Taiwan19F-14 SAM-dependent methyltransferase YP_002743074.1 1607422 R 487213 CDS YP_002743075.1 225861566 7686365 complement(1608271..1608624) 1 NC_012469.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; putative iojap homolog 1608624 7686365 SPT_1682 Streptococcus pneumoniae Taiwan19F-14 putative iojap homolog YP_002743075.1 1608271 R 487213 CDS YP_002743076.1 225861567 7686598 complement(1608637..1609137) 1 NC_012469.1 identified by match to protein family HMM PF00857; isochorismatase family protein 1609137 7686598 SPT_1683 Streptococcus pneumoniae Taiwan19F-14 isochorismatase family protein YP_002743076.1 1608637 R 487213 CDS YP_002743077.1 225861568 7685522 complement(1609138..1609731) 1 NC_012469.1 identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488; hypothetical protein 1609731 7685522 SPT_1684 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743077.1 1609138 R 487213 CDS YP_002743078.1 225861569 7687048 complement(1609731..1610360) 1 NC_012469.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1610360 nadD 7687048 nadD Streptococcus pneumoniae Taiwan19F-14 nicotinic acid mononucleotide adenylyltransferase YP_002743078.1 1609731 R 487213 CDS YP_002743079.1 225861570 7686009 complement(1610412..1610723) 1 NC_012469.1 identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein 1610723 7686009 SPT_1686 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743079.1 1610412 R 487213 CDS YP_002743080.1 225861571 7685779 complement(1610937..1612043) 1 NC_012469.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1612043 7685779 SPT_1687 Streptococcus pneumoniae Taiwan19F-14 GTP-binding protein YqeH YP_002743080.1 1610937 R 487213 CDS YP_002743081.1 225861572 7685618 complement(1612046..1612573) 1 NC_012469.1 identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668; had superfamily (subfamily iiia) phosphatase 1612573 yqeG 7685618 yqeG Streptococcus pneumoniae Taiwan19F-14 had superfamily (subfamily iiia) phosphatase YP_002743081.1 1612046 R 487213 CDS YP_002743082.1 225861573 7686594 complement(1612588..1613496) 1 NC_012469.1 identified by match to protein family HMM PF01544; CorA - magnesium and cobalt transporter 1613496 7686594 SPT_1689 Streptococcus pneumoniae Taiwan19F-14 CorA - magnesium and cobalt transporter YP_002743082.1 1612588 R 487213 CDS YP_002743083.1 225861574 7686416 complement(1613553..1614149) 1 NC_012469.1 identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel 1614149 7686416 SPT_1690 Streptococcus pneumoniae Taiwan19F-14 small conductance mechanosensitive ion channel YP_002743083.1 1613553 R 487213 CDS YP_002743084.1 225861575 7686305 1615528..1616481 1 NC_012469.1 identified by match to protein family HMM PF06081; integral membrane protein 1616481 7686305 SPT_1693 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002743084.1 1615528 D 487213 CDS YP_002743085.1 225861576 7685752 1616624..1617004 1 NC_012469.1 identified by match to protein family HMM PF01047; transcriptional regulator, putative 1617004 7685752 SPT_1694 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, putative YP_002743085.1 1616624 D 487213 CDS YP_002743086.1 225861577 7686234 1617103..1617324 1 NC_012469.1 hypothetical protein 1617324 7686234 SPT_1695 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743086.1 1617103 D 487213 CDS YP_002743087.1 225861578 7686630 1617341..1617655 1 NC_012469.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 1617655 trx 7686630 trx Streptococcus pneumoniae Taiwan19F-14 thioredoxin YP_002743087.1 1617341 D 487213 CDS YP_002743088.1 225861579 7687246 1617960..1618493 1 NC_012469.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1618493 7687246 SPT_1697 Streptococcus pneumoniae Taiwan19F-14 7-cyano-7-deazaguanine reductase YP_002743088.1 1617960 D 487213 CDS YP_002743089.1 225861580 7686548 1618543..1618881 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1618881 7686548 SPT_1698 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743089.1 1618543 D 487213 CDS YP_002743090.1 225861581 7685831 complement(1618971..1619639) 1 NC_012469.1 identified by match to protein family HMM PF00230; aquaporin Z - water channel protein 1619639 7685831 SPT_1699 Streptococcus pneumoniae Taiwan19F-14 aquaporin Z - water channel protein YP_002743090.1 1618971 R 487213 CDS YP_002743091.1 225861582 7686770 complement(1619750..1619929) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1619929 7686770 SPT_1700 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743091.1 1619750 R 487213 CDS YP_002743092.1 225861583 7685362 complement(1619936..1620310) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1620310 7685362 SPT_1701 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743092.1 1619936 R 487213 CDS YP_002743093.1 225861584 7685952 complement(1620372..1620527) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1620527 7685952 SPT_1702 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743093.1 1620372 R 487213 CDS YP_002743094.1 225861585 7686864 complement(1620550..1622346) 1 NC_012469.1 identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F 1622346 pepF2 7686864 pepF2 Streptococcus pneumoniae Taiwan19F-14 oligoendopeptidase F YP_002743094.1 1620550 R 487213 CDS YP_002743095.1 225861586 7686050 complement(1622357..1623100) 1 NC_012469.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1623100 7686050 SPT_1704 Streptococcus pneumoniae Taiwan19F-14 16S ribosomal RNA methyltransferase RsmE YP_002743095.1 1622357 R 487213 CDS YP_002743096.1 225861587 7686514 complement(1623102..1624052) 1 NC_012469.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1624052 prmA 7686514 prmA Streptococcus pneumoniae Taiwan19F-14 ribosomal protein L11 methyltransferase YP_002743096.1 1623102 R 487213 CDS YP_002743097.1 225861588 7687126 complement(1625135..1627270) 1 NC_012469.1 hypothetical protein 1627270 7687126 SPT_1708 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743097.1 1625135 R 487213 CDS YP_002743098.1 225861589 7685973 complement(1627380..1628252) 1 NC_012469.1 identified by match to protein family HMM PF00004; ATPase of the AAA+ class 1628252 7685973 SPT_1709 Streptococcus pneumoniae Taiwan19F-14 ATPase of the AAA+ class YP_002743098.1 1627380 R 487213 CDS YP_002743099.1 225861590 7686048 complement(1628524..1628682) 1 NC_012469.1 7,8-dihydro-8-oxoguanine-triphosphatase 1628682 7686048 SPT_1710 Streptococcus pneumoniae Taiwan19F-14 7,8-dihydro-8-oxoguanine-triphosphatase YP_002743099.1 1628524 R 487213 CDS YP_002743100.1 225861591 7687376 complement(1628663..1629751) 1 NC_012469.1 identified by match to protein family HMM PF02163; peptidase, M50 family protein 1629751 7687376 SPT_1711 Streptococcus pneumoniae Taiwan19F-14 peptidase, M50 family protein YP_002743100.1 1628663 R 487213 CDS YP_002743101.1 225861592 7685808 complement(1629770..1630240) 1 NC_012469.1 hypothetical protein 1630240 7685808 SPT_1712 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743101.1 1629770 R 487213 CDS YP_002743102.1 225861593 7685617 complement(1630531..1630983) 1 NC_012469.1 identified by match to protein family HMM PF03681; hypothetical protein 1630983 7685617 SPT_1713 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743102.1 1630531 R 487213 CDS YP_002743103.1 225861594 7686931 complement(1631020..1631199) 1 NC_012469.1 identified by match to protein family HMM PF07927; hypothetical protein 1631199 7686931 SPT_1714 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743103.1 1631020 R 487213 CDS YP_002743104.1 225861595 7687326 complement(1631336..1631515) 1 NC_012469.1 hypothetical protein 1631515 7687326 SPT_1715 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743104.1 1631336 R 487213 CDS YP_002743105.1 225861596 7686859 complement(1631680..1631919) 1 NC_012469.1 hypothetical protein 1631919 7686859 SPT_1716 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743105.1 1631680 R 487213 CDS YP_002743106.1 225861597 7687218 1632189..1633460 1 NC_012469.1 identified by match to protein family HMM PF00004; recombination factor protein RarA 1633460 7687218 SPT_1717 Streptococcus pneumoniae Taiwan19F-14 recombination factor protein RarA YP_002743106.1 1632189 D 487213 CDS YP_002743107.1 225861598 7685604 complement(1634007..1635326) 1 NC_012469.1 identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 1635326 7685604 SPT_1719 Streptococcus pneumoniae Taiwan19F-14 sucrose-6-phosphate hydrolase YP_002743107.1 1634007 R 487213 CDS YP_002743108.1 225861599 7686303 complement(1635336..1636952) 1 NC_012469.1 identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 1636952 7686303 SPT_1720 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002743108.1 1635336 R 487213 CDS YP_002743109.1 225861600 7686820 complement(1636981..1637871) 1 NC_012469.1 protein LplC 1637871 7686820 SPT_1721 Streptococcus pneumoniae Taiwan19F-14 protein LplC YP_002743109.1 1636981 R 487213 CDS YP_002743110.1 225861601 7686955 complement(1637882..1638799) 1 NC_012469.1 identified by match to protein family HMM PF00528; protein LplB 1638799 7686955 SPT_1722 Streptococcus pneumoniae Taiwan19F-14 protein LplB YP_002743110.1 1637882 R 487213 CDS YP_002743111.1 225861602 7687151 complement(1638949..1639950) 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar-binding transcriptional regulator, LacI family 1639950 7687151 SPT_1723 Streptococcus pneumoniae Taiwan19F-14 sugar-binding transcriptional regulator, LacI family YP_002743111.1 1638949 R 487213 CDS YP_002743112.1 225861603 7686002 complement(1640312..1641793) 1 NC_012469.1 identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280; M protein trans-acting positive transcriptional regulator 1641793 7686002 SPT_1724 Streptococcus pneumoniae Taiwan19F-14 M protein trans-acting positive transcriptional regulator YP_002743112.1 1640312 R 487213 CDS YP_002743113.1 225861604 7685487 1642236..1642400 1 NC_012469.1 identified by match to protein family HMM PF04226; hypothetical protein 1642400 7685487 SPT_1725 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743113.1 1642236 D 487213 CDS YP_002743114.1 225861605 7685930 1642484..1643050 1 NC_012469.1 hypothetical protein 1643050 7685930 SPT_1726 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743114.1 1642484 D 487213 CDS YP_002743115.1 225861606 7687198 1643062..1643232 1 NC_012469.1 lipoprotein, putative 1643232 7687198 SPT_1727 Streptococcus pneumoniae Taiwan19F-14 lipoprotein, putative YP_002743115.1 1643062 D 487213 CDS YP_002743116.1 225861607 7685273 1643271..1643879 1 NC_012469.1 identified by match to protein family HMM PF03780; Gls24 protein 1643879 7685273 SPT_1728 Streptococcus pneumoniae Taiwan19F-14 Gls24 protein YP_002743116.1 1643271 D 487213 CDS YP_002743117.1 225861608 7685389 1643910..1644113 1 NC_012469.1 identified by match to protein family HMM PF05532; hypothetical protein 1644113 7685389 SPT_1729 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743117.1 1643910 D 487213 CDS YP_002743118.1 225861609 7685980 complement(1644640..1645086) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1645086 7685980 SPT_1730 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002743118.1 1644640 R 487213 CDS YP_002743119.1 225861610 7685853 1645156..1645815 1 NC_012469.1 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type 4 prepilin peptidase 1645815 7685853 SPT_1731 Streptococcus pneumoniae Taiwan19F-14 type 4 prepilin peptidase YP_002743119.1 1645156 D 487213 CDS YP_002743120.1 225861611 7686555 complement(1645867..1647018) 1 NC_012469.1 identified by match to protein family HMM PF01381; match to protein family HMM PF06114; transcriptional regulator 1647018 7686555 SPT_1732 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator YP_002743120.1 1645867 R 487213 CDS YP_002743121.1 225861612 7685734 complement(1647033..1647764) 1 NC_012469.1 hypothetical protein 1647764 7685734 SPT_1733 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743121.1 1647033 R 487213 CDS YP_002743122.1 225861613 7686060 complement(1648066..1648842) 1 NC_012469.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1648842 trpA 7686060 trpA Streptococcus pneumoniae Taiwan19F-14 tryptophan synthase subunit alpha YP_002743122.1 1648066 R 487213 CDS YP_002743123.1 225861614 7685391 complement(1648835..1650058) 1 NC_012469.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1650058 trpB 7685391 trpB Streptococcus pneumoniae Taiwan19F-14 tryptophan synthase subunit beta YP_002743123.1 1648835 R 487213 CDS YP_002743124.1 225861615 7685355 complement(1650036..1650635) 1 NC_012469.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1650635 trpF 7685355 trpF Streptococcus pneumoniae Taiwan19F-14 N-(5'-phosphoribosyl)anthranilate isomerase YP_002743124.1 1650036 R 487213 CDS YP_002743125.1 225861616 7686753 complement(1650622..1651389) 1 NC_012469.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1651389 trpC 7686753 trpC Streptococcus pneumoniae Taiwan19F-14 indole-3-glycerol-phosphate synthase YP_002743125.1 1650622 R 487213 CDS YP_002743126.1 225861617 7685916 complement(1651386..1652390) 1 NC_012469.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1652390 trpD 7685916 trpD Streptococcus pneumoniae Taiwan19F-14 anthranilate phosphoribosyltransferase YP_002743126.1 1651386 R 487213 CDS YP_002743127.1 225861618 7685471 complement(1652401..1652967) 1 NC_012469.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 1652967 pabA 7685471 pabA Streptococcus pneumoniae Taiwan19F-14 anthranilate synthase component II YP_002743127.1 1652401 R 487213 CDS YP_002743128.1 225861619 7686475 complement(1652964..1654325) 1 NC_012469.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1654325 trpE 7686475 trpE Streptococcus pneumoniae Taiwan19F-14 anthranilate synthase component I YP_002743128.1 1652964 R 487213 CDS YP_002743129.1 225861620 7686512 complement(1654697..1655038) 1 NC_012469.1 chlorohydrolase 1655038 7686512 SPT_1741 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002743129.1 1654697 R 487213 CDS YP_002743130.1 225861621 7685357 complement(1655646..1656647) 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; catabolite control protein 1656647 7685357 SPT_1742 Streptococcus pneumoniae Taiwan19F-14 catabolite control protein YP_002743130.1 1655646 R 487213 CDS YP_002743131.1 225861622 7686096 complement(1657218..1657928) 1 NC_012469.1 identified by match to protein family HMM PF02308; putative Mg2+ transporter-C (MgtC) family protein 1657928 7686096 SPT_1743 Streptococcus pneumoniae Taiwan19F-14 putative Mg2+ transporter-C (MgtC) family protein YP_002743131.1 1657218 R 487213 CDS YP_002743132.1 225861623 7686338 complement(1657931..1659622) 1 NC_012469.1 identified by match to protein family HMM PF00528; binding-protein-dependent transport systems inner membrane component 1659622 7686338 SPT_1744 Streptococcus pneumoniae Taiwan19F-14 binding-protein-dependent transport systems inner membrane component YP_002743132.1 1657931 R 487213 CDS YP_002743133.1 225861624 7687134 complement(1659634..1660644) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; spermidine/putrescine import ATP-binding protein PotA 1660644 7687134 SPT_1745 Streptococcus pneumoniae Taiwan19F-14 spermidine/putrescine import ATP-binding protein PotA YP_002743133.1 1659634 R 487213 CDS YP_002743134.1 225861625 7686706 complement(1660747..1661814) 1 NC_012469.1 ABC transporter substrate-binding protein 1661814 7686706 SPT_1746 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002743134.1 1660747 R 487213 CDS YP_002743135.1 225861626 7686218 complement(1661839..1662498) 1 NC_012469.1 identified by match to protein family HMM PF08975; hypothetical protein 1662498 7686218 SPT_1747 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743135.1 1661839 R 487213 CDS YP_002743136.1 225861627 7685733 complement(1662665..1663675) 1 NC_012469.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 1663675 galE2 7685733 galE2 Streptococcus pneumoniae Taiwan19F-14 UDP-glucose 4-epimerase YP_002743136.1 1662665 R 487213 CDS YP_002743137.1 225861628 7685524 complement(1663688..1665163) 1 NC_012469.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1665163 galT1 7685524 galT1 Streptococcus pneumoniae Taiwan19F-14 galactose-1-phosphate uridylyltransferase YP_002743137.1 1663688 R 487213 CDS YP_002743138.1 225861629 7686295 complement(1665176..1665817) 1 NC_012469.1 identified by match to protein family HMM PF01895; PhoU family 1665817 7686295 SPT_1750 Streptococcus pneumoniae Taiwan19F-14 PhoU family YP_002743138.1 1665176 R 487213 CDS YP_002743139.1 225861630 7686536 complement(1665875..1666621) 1 NC_012469.1 hypothetical protein 1666621 7686536 SPT_1751 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743139.1 1665875 R 487213 CDS YP_002743140.1 225861631 7686958 complement(1666605..1668683) 1 NC_012469.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168; cell wall surface anchor family protein 1668683 7686958 SPT_1752 Streptococcus pneumoniae Taiwan19F-14 cell wall surface anchor family protein YP_002743140.1 1666605 R 487213 CDS YP_002743141.1 225861632 7686077 complement(1669191..1669310) 1 NC_012469.1 hypothetical protein 1669310 7686077 SPT_1753 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743141.1 1669191 R 487213 CDS YP_002743142.1 225861633 7686164 complement(1669604..1670830) 1 NC_012469.1 identified by match to protein family HMM PF01041; Cps7G 1670830 7686164 SPT_1754 Streptococcus pneumoniae Taiwan19F-14 Cps7G YP_002743142.1 1669604 R 487213 CDS YP_002743143.1 225861634 7686462 complement(1670873..1671565) 1 NC_012469.1 identified by match to protein family HMM PF02397; sugar transferase family protein 1671565 7686462 SPT_1755 Streptococcus pneumoniae Taiwan19F-14 sugar transferase family protein YP_002743143.1 1670873 R 487213 CDS YP_002743144.1 225861635 7687152 complement(1671749..1673491) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1673491 7687152 SPT_1756 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002743144.1 1671749 R 487213 CDS YP_002743145.1 225861636 7685932 complement(1673481..1675226) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 1675226 7685932 SPT_1757 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002743145.1 1673481 R 487213 CDS YP_002743146.1 225861637 7686565 complement(1675432..1675728) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1675728 7686565 SPT_1758 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743146.1 1675432 R 487213 CDS YP_002743147.1 225861638 7686351 complement(1675881..1676150) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1676150 7686351 SPT_1759 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743147.1 1675881 R 487213 CDS YP_002743148.1 225861639 7687396 complement(1676181..1676336) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1676336 7687396 SPT_1760 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743148.1 1676181 R 487213 CDS YP_002743149.1 225861640 7687022 1676470..1677297 1 NC_012469.1 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1677297 xth 7687022 xth Streptococcus pneumoniae Taiwan19F-14 exodeoxyribonuclease III YP_002743149.1 1676470 D 487213 CDS YP_002743150.1 225861641 7686910 1678573..1679154 1 NC_012469.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1679154 xpt 7686910 xpt Streptococcus pneumoniae Taiwan19F-14 xanthine phosphoribosyltransferase YP_002743150.1 1678573 D 487213 CDS YP_002743151.1 225861642 7686665 1679154..1680416 1 NC_012469.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 1680416 7686665 SPT_1765 Streptococcus pneumoniae Taiwan19F-14 xanthine permease YP_002743151.1 1679154 D 487213 CDS YP_002743152.1 225861643 7685784 complement(1680467..1680928) 1 NC_012469.1 protein DpnD 1680928 7685784 SPT_1766 Streptococcus pneumoniae Taiwan19F-14 protein DpnD YP_002743152.1 1680467 R 487213 CDS YP_002743153.1 225861644 7686800 complement(1680925..1681689) 1 NC_012469.1 identified by match to protein family HMM PF06044; type II restriction enzyme 1681689 7686800 SPT_1767 Streptococcus pneumoniae Taiwan19F-14 type II restriction enzyme YP_002743153.1 1680925 R 487213 CDS YP_002743154.1 225861645 7687078 complement(1681870..1682274) 1 NC_012469.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; thioesterase family protein 1682274 7687078 SPT_1768 Streptococcus pneumoniae Taiwan19F-14 thioesterase family protein YP_002743154.1 1681870 R 487213 CDS YP_002743155.1 225861646 7686614 complement(1682344..1683825) 1 NC_012469.1 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 1683825 galT2 7686614 galT2 Streptococcus pneumoniae Taiwan19F-14 galactose-1-phosphate uridylyltransferase YP_002743155.1 1682344 R 487213 CDS YP_002743156.1 225861647 7685612 complement(1683844..1685022) 1 NC_012469.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1685022 galK 7685612 galK Streptococcus pneumoniae Taiwan19F-14 galactokinase YP_002743156.1 1683844 R 487213 CDS YP_002743157.1 225861648 7685788 1685186..1686193 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon 1686193 7685788 SPT_1771 Streptococcus pneumoniae Taiwan19F-14 GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon YP_002743157.1 1685186 D 487213 CDS YP_002743158.1 225861649 7686196 complement(1686239..1687276) 1 NC_012469.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase, zinc-containing 1687276 7686196 SPT_1772 Streptococcus pneumoniae Taiwan19F-14 alcohol dehydrogenase, zinc-containing YP_002743158.1 1686239 R 487213 CDS YP_002743159.1 225861650 7687043 complement(1687277..1687630) 1 NC_012469.1 identified by match to protein family HMM PF00376; transcriptional regulator, MerR family 1687630 7687043 SPT_1773 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, MerR family YP_002743159.1 1687277 R 487213 CDS YP_002743160.1 225861651 7687064 complement(1687874..1688764) 1 NC_012469.1 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation diffusion facilitator transporter - heavy metal transport 1688764 7687064 SPT_1774 Streptococcus pneumoniae Taiwan19F-14 cation diffusion facilitator transporter - heavy metal transport YP_002743160.1 1687874 R 487213 CDS YP_002743161.1 225861652 7685226 1688897..1689433 1 NC_012469.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1689433 7685226 SPT_1775 Streptococcus pneumoniae Taiwan19F-14 TetR family transcriptional regulator YP_002743161.1 1688897 D 487213 CDS YP_002743162.1 225861653 7686032 complement(1689599..1690405) 1 NC_012469.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter 1690405 7686032 SPT_1776 Streptococcus pneumoniae Taiwan19F-14 nicotinamide mononucleotide transporter YP_002743162.1 1689599 R 487213 CDS YP_002743163.1 225861654 7686853 complement(1690576..1690692) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1690692 7686853 SPT_1777 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743163.1 1690576 R 487213 CDS YP_002743164.1 225861655 7686915 complement(1690750..1692270) 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM PF04069; choline ABC transporter permease 1692270 7686915 SPT_1778 Streptococcus pneumoniae Taiwan19F-14 choline ABC transporter permease YP_002743164.1 1690750 R 487213 CDS YP_002743165.1 225861656 7686092 complement(1692263..1692991) 1 NC_012469.1 identified by match to protein family HMM PF00005; choline transport ATP-binding protein opuBA 1692991 7686092 SPT_1779 Streptococcus pneumoniae Taiwan19F-14 choline transport ATP-binding protein opuBA YP_002743165.1 1692263 R 487213 CDS YP_002743166.1 225861657 7687375 complement(1693006..1693770) 1 NC_012469.1 identified by match to protein family HMM PF07366; hypothetical protein 1693770 7687375 SPT_1780 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743166.1 1693006 R 487213 CDS YP_002743167.1 225861658 7685326 complement(1693774..1694217) 1 NC_012469.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 1694217 7685326 SPT_1781 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, MarR family YP_002743167.1 1693774 R 487213 CDS YP_002743168.1 225861659 7686842 complement(1694899..1695195) 1 NC_012469.1 hypothetical protein 1695195 7686842 SPT_1782 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743168.1 1694899 R 487213 CDS YP_002743169.1 225861660 7687101 complement(1695217..1696281) 1 NC_012469.1 identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107; glutamyl aminopeptidase 1696281 pepA 7687101 pepA Streptococcus pneumoniae Taiwan19F-14 glutamyl aminopeptidase YP_002743169.1 1695217 R 487213 CDS YP_002743170.1 225861661 7686620 1697398..1697550 1 NC_012469.1 hypothetical protein 1697550 7686620 SPT_1785 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743170.1 1697398 D 487213 CDS YP_002743171.1 225861662 7686025 1697847..1698806 1 NC_012469.1 identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 1698806 7686025 SPT_1786 Streptococcus pneumoniae Taiwan19F-14 Fe3+ ABC transporter permease YP_002743171.1 1697847 D 487213 CDS YP_002743172.1 225861663 7685280 1698796..1699752 1 NC_012469.1 identified by match to protein family HMM PF01032; iron-compound ABC transporter, permease protein 1699752 7685280 SPT_1787 Streptococcus pneumoniae Taiwan19F-14 iron-compound ABC transporter, permease protein YP_002743172.1 1698796 D 487213 CDS YP_002743173.1 225861664 7686117 1699749..1700501 1 NC_012469.1 identified by match to protein family HMM PF00005; ferrichrome transport ATP-binding protein FhuC 1700501 7686117 SPT_1788 Streptococcus pneumoniae Taiwan19F-14 ferrichrome transport ATP-binding protein FhuC YP_002743173.1 1699749 D 487213 CDS YP_002743174.1 225861665 7685815 1700597..1701562 1 NC_012469.1 identified by match to protein family HMM PF01497; iron-compound ABC transporter, iron-compound-binding protein 1701562 7685815 SPT_1789 Streptococcus pneumoniae Taiwan19F-14 iron-compound ABC transporter, iron-compound-binding protein YP_002743174.1 1700597 D 487213 CDS YP_002743175.1 225861666 7686895 complement(1701787..1702029) 1 NC_012469.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 1702029 7686895 SPT_1790 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743175.1 1701787 R 487213 CDS YP_002743176.1 225861667 7686353 complement(1702029..1702751) 1 NC_012469.1 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 1702751 rluB 7686353 rluB Streptococcus pneumoniae Taiwan19F-14 ribosomal large subunit pseudouridine synthase B YP_002743176.1 1702029 R 487213 CDS YP_002743177.1 225861668 7686868 complement(1702738..1703307) 1 NC_012469.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B 1703307 scpB 7686868 scpB Streptococcus pneumoniae Taiwan19F-14 segregation and condensation protein B YP_002743177.1 1702738 R 487213 CDS YP_002743178.1 225861669 7687129 complement(1703326..1704054) 1 NC_012469.1 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 1704054 scpA 7687129 scpA Streptococcus pneumoniae Taiwan19F-14 segregation and condensation protein A YP_002743178.1 1703326 R 487213 CDS YP_002743179.1 225861670 7686921 complement(1704054..1704794) 1 NC_012469.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein 1704794 xerD 7686921 xerD Streptococcus pneumoniae Taiwan19F-14 site-specific tyrosine recombinase XerD-like protein YP_002743179.1 1704054 R 487213 CDS YP_002743180.1 225861671 7686056 complement(1704785..1705246) 1 NC_012469.1 identified by match to protein family HMM PF00571; CBS domain protein 1705246 7686056 SPT_1795 Streptococcus pneumoniae Taiwan19F-14 CBS domain protein YP_002743180.1 1704785 R 487213 CDS YP_002743181.1 225861672 7685810 complement(1705243..1705764) 1 NC_012469.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase, family 1705764 7685810 SPT_1796 Streptococcus pneumoniae Taiwan19F-14 phosphodiesterase, family YP_002743181.1 1705243 R 487213 CDS YP_002743182.1 225861673 7687032 complement(1705740..1706711) 1 NC_012469.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein 1706711 7687032 SPT_1797 Streptococcus pneumoniae Taiwan19F-14 deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein YP_002743182.1 1705740 R 487213 CDS YP_002743183.1 225861674 7687343 complement(1706708..1707502) 1 NC_012469.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1707502 murI 7687343 murI Streptococcus pneumoniae Taiwan19F-14 glutamate racemase YP_002743183.1 1706708 R 487213 CDS YP_002743184.1 225861675 7686333 complement(1707709..1707957) 1 NC_012469.1 identified by match to protein family HMM PF03672; hypothetical protein 1707957 7686333 SPT_1799 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743184.1 1707709 R 487213 CDS YP_002743185.1 225861676 7687238 complement(1708213..1709838) 1 NC_012469.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; trehalose-6-phosphate hydrolase 1709838 7687238 SPT_1800 Streptococcus pneumoniae Taiwan19F-14 trehalose-6-phosphate hydrolase YP_002743185.1 1708213 R 487213 CDS YP_002743186.1 225861677 7686329 complement(1710016..1711983) 1 NC_012469.1 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992; pts system, trehalose-specific iibc component 1711983 treP 7686329 treP Streptococcus pneumoniae Taiwan19F-14 pts system, trehalose-specific iibc component YP_002743186.1 1710016 R 487213 CDS YP_002743187.1 225861678 7686736 1712168..1712878 1 NC_012469.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404; trehalose operon repressor 1712878 treR 7686736 treR Streptococcus pneumoniae Taiwan19F-14 trehalose operon repressor YP_002743187.1 1712168 D 487213 CDS YP_002743188.1 225861679 7686553 complement(1716144..1717070) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; oligopeptide transport ATP-binding protein AmiF 1717070 7686553 SPT_1809 Streptococcus pneumoniae Taiwan19F-14 oligopeptide transport ATP-binding protein AmiF YP_002743188.1 1716144 R 487213 CDS YP_002743189.1 225861680 7687011 complement(1717081..1718148) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein OppD 1718148 7687011 SPT_1810 Streptococcus pneumoniae Taiwan19F-14 oligopeptide transport ATP-binding protein OppD YP_002743189.1 1717081 R 487213 CDS YP_002743190.1 225861681 7685238 complement(1718157..1719083) 1 NC_012469.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AmiD 1719083 7685238 SPT_1811 Streptococcus pneumoniae Taiwan19F-14 oligopeptide transport system permease protein AmiD YP_002743190.1 1718157 R 487213 CDS YP_002743191.1 225861682 7685377 complement(1719083..1720579) 1 NC_012469.1 identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AmiC 1720579 7685377 SPT_1812 Streptococcus pneumoniae Taiwan19F-14 oligopeptide transport system permease protein AmiC YP_002743191.1 1719083 R 487213 CDS YP_002743192.1 225861683 7685252 complement(1720646..1722625) 1 NC_012469.1 identified by match to protein family HMM PF00496; AmiA protein 1722625 7685252 SPT_1813 Streptococcus pneumoniae Taiwan19F-14 AmiA protein YP_002743192.1 1720646 R 487213 CDS YP_002743193.1 225861684 7685292 complement(1723311..1724504) 1 NC_012469.1 identified by match to protein family HMM PF04932; O-antigen polymerase family 1724504 7685292 SPT_1814 Streptococcus pneumoniae Taiwan19F-14 O-antigen polymerase family YP_002743193.1 1723311 R 487213 CDS YP_002743194.1 225861685 7686799 complement(1724642..1726084) 1 NC_012469.1 identified by match to protein family HMM PF00128; sucrose phosphorylase (Sucrose glucosyltransferase)(Glucosyltransferase-A) (GTF-A) 1726084 7686799 SPT_1815 Streptococcus pneumoniae Taiwan19F-14 sucrose phosphorylase (Sucrose glucosyltransferase)(Glucosyltransferase-A) (GTF-A) YP_002743194.1 1724642 R 487213 CDS YP_002743195.1 225861686 7685787 complement(1726295..1726435) 1 NC_012469.1 chlorohydrolase 1726435 7685787 SPT_1816 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002743195.1 1726295 R 487213 CDS YP_002743196.1 225861687 7686870 complement(1726442..1727275) 1 NC_012469.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1727275 7686870 SPT_1817 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter permease YP_002743196.1 1726442 R 487213 CDS YP_002743197.1 225861688 7686192 complement(1727289..1728155) 1 NC_012469.1 identified by match to protein family HMM PF00528; sugar ABC transporter permease 1728155 7686192 SPT_1818 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter permease YP_002743197.1 1727289 R 487213 CDS YP_002743198.1 225861689 7687240 complement(1728169..1729428) 1 NC_012469.1 identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein 1729428 7687240 SPT_1819 Streptococcus pneumoniae Taiwan19F-14 sugar ABC transporter substrate-binding protein YP_002743198.1 1728169 R 487213 CDS YP_002743199.1 225861690 7685899 complement(1729520..1731682) 1 NC_012469.1 identified by match to protein family HMM PF02065; alpha-galactosidase (Melibiase) 1731682 7685899 SPT_1821 Streptococcus pneumoniae Taiwan19F-14 alpha-galactosidase (Melibiase) YP_002743199.1 1729520 R 487213 CDS YP_002743200.1 225861691 7685531 1731790..1732650 1 NC_012469.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; Msm operon regulatory protein 1732650 7685531 SPT_1822 Streptococcus pneumoniae Taiwan19F-14 Msm operon regulatory protein YP_002743200.1 1731790 D 487213 CDS YP_002743201.1 225861692 7686811 1732647..1733582 1 NC_012469.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1733582 7686811 SPT_1823 Streptococcus pneumoniae Taiwan19F-14 biotin--protein ligase YP_002743201.1 1732647 D 487213 CDS YP_002743202.1 225861693 7685581 complement(1740485..1741840) 1 NC_012469.1 identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 1741840 rumA2 7685581 rumA2 Streptococcus pneumoniae Taiwan19F-14 23S rRNA (uracil-5-)-methyltransferase RumA YP_002743202.1 1740485 R 487213 CDS YP_002743203.1 225861694 7687350 1741878..1742654 1 NC_012469.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1742654 recX 7687350 recX Streptococcus pneumoniae Taiwan19F-14 recombination regulator RecX YP_002743203.1 1741878 D 487213 CDS YP_002743204.1 225861695 7685794 1742743..1743276 1 NC_012469.1 identified by match to protein family HMM PF04167; hypothetical protein 1743276 7685794 SPT_1848 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743204.1 1742743 D 487213 CDS YP_002743205.1 225861696 7685287 complement(1743631..1743837) 1 NC_012469.1 hypothetical protein 1743837 7685287 SPT_1849 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743205.1 1743631 R 487213 CDS YP_002743206.1 225861697 7685227 complement(1744499..1745272) 1 NC_012469.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; MerR-family transcriptional regulator 1745272 7685227 SPT_1851 Streptococcus pneumoniae Taiwan19F-14 MerR-family transcriptional regulator YP_002743206.1 1744499 R 487213 CDS YP_002743207.1 225861698 7685300 1745345..1745464 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1745464 7685300 SPT_1852 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743207.1 1745345 D 487213 CDS YP_002743208.1 225861699 7686570 complement(1746613..1748235) 1 NC_012469.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1748235 groEL 7686570 groEL Streptococcus pneumoniae Taiwan19F-14 chaperonin GroEL YP_002743208.1 1746613 R 487213 CDS YP_002743209.1 225861700 7685519 complement(1748251..1748535) 1 NC_012469.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1748535 groES 7685519 groES Streptococcus pneumoniae Taiwan19F-14 co-chaperonin GroES YP_002743209.1 1748251 R 487213 CDS YP_002743210.1 225861701 7685402 complement(1748691..1749086) 1 NC_012469.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 1749086 7685402 SPT_1857 Streptococcus pneumoniae Taiwan19F-14 single-stranded DNA-binding protein YP_002743210.1 1748691 R 487213 CDS YP_002743211.1 225861702 7686412 complement(1749164..1749925) 1 NC_012469.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659; oxidoreductase, short chain dehydrogenase/reductase family 1749925 7686412 SPT_1858 Streptococcus pneumoniae Taiwan19F-14 oxidoreductase, short chain dehydrogenase/reductase family YP_002743211.1 1749164 R 487213 CDS YP_002743212.1 225861703 7687180 complement(1749958..1750584) 1 NC_012469.1 identified by match to protein family HMM PF01588; putative tRNA binding domain protein 1750584 7687180 SPT_1859 Streptococcus pneumoniae Taiwan19F-14 putative tRNA binding domain protein YP_002743212.1 1749958 R 487213 CDS YP_002743213.1 225861704 7685342 complement(1750600..1750917) 1 NC_012469.1 identified by match to protein family HMM PF00085; thioredoxin family protein 1750917 7685342 SPT_1860 Streptococcus pneumoniae Taiwan19F-14 thioredoxin family protein YP_002743213.1 1750600 R 487213 CDS YP_002743214.1 225861705 7686043 complement(1750914..1751213) 1 NC_012469.1 hypothetical protein 1751213 7686043 SPT_1861 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743214.1 1750914 R 487213 CDS YP_002743215.1 225861706 7686028 1751307..1751438 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1751438 7686028 SPT_1862 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743215.1 1751307 D 487213 CDS YP_002743216.1 225861707 7686654 complement(1751463..1751588) 1 NC_012469.1 identified by match to protein family HMM PF01473; choline binding protein G 1751588 7686654 SPT_1863 Streptococcus pneumoniae Taiwan19F-14 choline binding protein G YP_002743216.1 1751463 R 487213 CDS YP_002743217.1 225861708 7685871 complement(1751903..1752577) 1 NC_012469.1 hypothetical protein 1752577 7685871 SPT_1864 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743217.1 1751903 R 487213 CDS YP_002743218.1 225861709 7685496 complement(1752582..1753028) 1 NC_012469.1 identified by match to protein family HMM PF04397; response regulator of the LytR/AlgR family 1753028 7685496 SPT_1865 Streptococcus pneumoniae Taiwan19F-14 response regulator of the LytR/AlgR family YP_002743218.1 1752582 R 487213 CDS YP_002743219.1 225861710 7685460 complement(1753142..1753645) 1 NC_012469.1 identified by match to protein family HMM PF01569; PAP2 family protein 1753645 7685460 SPT_1866 Streptococcus pneumoniae Taiwan19F-14 PAP2 family protein YP_002743219.1 1753142 R 487213 CDS YP_002743220.1 225861711 7686900 complement(1753642..1754004) 1 NC_012469.1 hypothetical protein 1754004 7686900 SPT_1867 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743220.1 1753642 R 487213 CDS YP_002743221.1 225861712 7687155 complement(1754070..1755101) 1 NC_012469.1 identified by match to protein family HMM PF00005; multidrug resistance protein 3 (P-glycoprotein C) 1755101 7687155 SPT_1868 Streptococcus pneumoniae Taiwan19F-14 multidrug resistance protein 3 (P-glycoprotein C) YP_002743221.1 1754070 R 487213 CDS YP_002743222.1 225861713 7687345 complement(1755108..1755929) 1 NC_012469.1 identified by match to protein family HMM PF00664; ABC transporter permease 1755929 7687345 SPT_1869 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002743222.1 1755108 R 487213 CDS YP_002743223.1 225861714 7685862 complement(1756047..1756418) 1 NC_012469.1 identified by match to protein family HMM PF01047; transcriptional regulator, MarR family 1756418 7685862 SPT_1870 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, MarR family YP_002743223.1 1756047 R 487213 CDS YP_002743224.1 225861715 7686539 complement(1756542..1757258) 1 NC_012469.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 1757258 7686539 SPT_1871 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743224.1 1756542 R 487213 CDS YP_002743225.1 225861716 7685631 complement(1758139..1759554) 1 NC_012469.1 identified by match to protein family HMM PF01289; pneumolysin (Thiol-activated cytolysin) 1759554 7685631 SPT_1872 Streptococcus pneumoniae Taiwan19F-14 pneumolysin (Thiol-activated cytolysin) YP_002743225.1 1758139 R 487213 CDS YP_002743226.1 225861717 7685699 complement(1759565..1759897) 1 NC_012469.1 hypothetical protein 1759897 7685699 SPT_1873 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743226.1 1759565 R 487213 CDS YP_002743227.1 225861718 7686928 complement(1759968..1760576) 1 NC_012469.1 hypothetical protein 1760576 7686928 SPT_1874 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743227.1 1759968 R 487213 CDS YP_002743228.1 225861719 7687109 complement(1760589..1761047) 1 NC_012469.1 hypothetical protein 1761047 7687109 SPT_1875 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743228.1 1760589 R 487213 CDS YP_002743229.1 225861720 7686459 1761172..1761303 1 NC_012469.1 mobile genetic element 1761303 7686459 SPT_1876 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002743229.1 1761172 D 487213 CDS YP_002743230.1 225861721 7685987 1761308..1761571 1 NC_012469.1 mobile genetic element 1761571 7685987 SPT_1877 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002743230.1 1761308 D 487213 CDS YP_002743231.1 225861722 7686160 1762048..1762881 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1762881 7686160 SPT_1878 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743231.1 1762048 D 487213 CDS YP_002743232.1 225861723 7686529 1762908..1763969 1 NC_012469.1 ABC transporter substrate-binding protein 1763969 7686529 SPT_1879 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002743232.1 1762908 D 487213 CDS YP_002743233.1 225861724 7685743 1763986..1764990 1 NC_012469.1 identified by match to protein family HMM PF00005; spermidine/putrescine import ATP-binding protein PotA 1764990 7685743 SPT_1880 Streptococcus pneumoniae Taiwan19F-14 spermidine/putrescine import ATP-binding protein PotA YP_002743233.1 1763986 D 487213 CDS YP_002743234.1 225861725 7685445 1767445..1768044 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; hydrolase 1768044 7685445 SPT_1884 Streptococcus pneumoniae Taiwan19F-14 hydrolase YP_002743234.1 1767445 D 487213 CDS YP_002743235.1 225861726 7685303 1768054..1770081 1 NC_012469.1 identified by match to protein family HMM PF00356; transcriptional regulator, LacI family protein 1770081 7685303 SPT_1885 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, LacI family protein YP_002743235.1 1768054 D 487213 CDS YP_002743236.1 225861727 7685478 1770240..1770371 1 NC_012469.1 mobile genetic element 1770371 7685478 SPT_1886 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002743236.1 1770240 D 487213 CDS YP_002743237.1 225861728 7686358 1770376..1770639 1 NC_012469.1 mobile genetic element 1770639 7686358 SPT_1887 Streptococcus pneumoniae Taiwan19F-14 mobile genetic element YP_002743237.1 1770376 D 487213 CDS YP_002743238.1 225861729 7686542 complement(1771377..1771637) 1 NC_012469.1 hypothetical protein 1771637 7686542 SPT_1888 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743238.1 1771377 R 487213 CDS YP_002743239.1 225861730 7686545 complement(1771696..1772247) 1 NC_012469.1 hypothetical protein 1772247 7686545 SPT_1889 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743239.1 1771696 R 487213 CDS YP_002743240.1 225861731 7687206 complement(1772237..1772434) 1 NC_012469.1 hypothetical protein 1772434 7687206 SPT_1890 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743240.1 1772237 R 487213 CDS YP_002743241.1 225861732 7685272 complement(1772438..1773232) 1 NC_012469.1 hypothetical protein 1773232 7685272 SPT_1891 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743241.1 1772438 R 487213 CDS YP_002743242.1 225861733 7685510 complement(1773640..1774065) 1 NC_012469.1 hypothetical protein 1774065 7685510 SPT_1892 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743242.1 1773640 R 487213 CDS YP_002743243.1 225861734 7686198 complement(1774194..1774553) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1774553 7686198 SPT_1893 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743243.1 1774194 R 487213 CDS YP_002743244.1 225861735 7685844 complement(1774792..1774953) 1 NC_012469.1 type II restriction-modification system regulatory protein, putative 1774953 7685844 SPT_1894 Streptococcus pneumoniae Taiwan19F-14 type II restriction-modification system regulatory protein, putative YP_002743244.1 1774792 R 487213 CDS YP_002743245.1 225861736 7687253 complement(1775312..1776268) 1 NC_012469.1 identified by match to protein family HMM PF01473; match to protein family HMM PF01510; autolysin (N-acetylmuramoyl-L-alanine amidase) (Mureinhydrolase) (Mucopeptide aminohydrolase) (Cell wall hydrolase) 1776268 7687253 SPT_1895 Streptococcus pneumoniae Taiwan19F-14 autolysin (N-acetylmuramoyl-L-alanine amidase) (Mureinhydrolase) (Mucopeptide aminohydrolase) (Cell wall hydrolase) YP_002743245.1 1775312 R 487213 CDS YP_002743246.1 225861737 7685769 complement(1776396..1776509) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1776509 7685769 SPT_1896 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743246.1 1776396 R 487213 CDS YP_002743247.1 225861738 7687015 complement(1776644..1778014) 1 NC_012469.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible protein 1778014 7687015 SPT_1897 Streptococcus pneumoniae Taiwan19F-14 DNA-damage-inducible protein YP_002743247.1 1776644 R 487213 CDS YP_002743248.1 225861739 7686410 complement(1778321..1779487) 1 NC_012469.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1779487 recA 7686410 recA Streptococcus pneumoniae Taiwan19F-14 recombinase A YP_002743248.1 1778321 R 487213 CDS YP_002743249.1 225861740 7687088 complement(1779542..1780798) 1 NC_012469.1 identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; competence damage-inducible protein A 1780798 7687088 SPT_1899 Streptococcus pneumoniae Taiwan19F-14 competence damage-inducible protein A YP_002743249.1 1779542 R 487213 CDS YP_002743250.1 225861741 7687044 complement(1780883..1781899) 1 NC_012469.1 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; regulator of lytrabc operon 1781899 7687044 SPT_1900 Streptococcus pneumoniae Taiwan19F-14 regulator of lytrabc operon YP_002743250.1 1780883 R 487213 CDS YP_002743251.1 225861742 7687261 complement(1781907..1782425) 1 NC_012469.1 identified by match to protein family HMM PF00583; acetyltransferase, gnat family 1782425 7687261 SPT_1901 Streptococcus pneumoniae Taiwan19F-14 acetyltransferase, gnat family YP_002743251.1 1781907 R 487213 CDS YP_002743252.1 225861743 7686262 complement(1782415..1782858) 1 NC_012469.1 identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 1782858 7686262 SPT_1902 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743252.1 1782415 R 487213 CDS YP_002743253.1 225861744 7686556 complement(1782944..1783564) 1 NC_012469.1 lipoprotein, putative 1783564 7686556 SPT_1903 Streptococcus pneumoniae Taiwan19F-14 lipoprotein, putative YP_002743253.1 1782944 R 487213 CDS YP_002743254.1 225861745 7686453 complement(1783870..1784733) 1 NC_012469.1 identified by match to protein family HMM PF01381; transcriptional activator 1784733 7686453 SPT_1904 Streptococcus pneumoniae Taiwan19F-14 transcriptional activator YP_002743254.1 1783870 R 487213 CDS YP_002743255.1 225861746 7686766 1784924..1785094 1 NC_012469.1 hypothetical protein 1785094 7686766 SPT_1905 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743255.1 1784924 D 487213 CDS YP_002743256.1 225861747 7686422 1785354..1785473 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1785473 7686422 SPT_1906 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743256.1 1785354 D 487213 CDS YP_002743257.1 225861748 7685728 1785496..1785810 1 NC_012469.1 identified by match to protein family HMM PF06125; conjugative transposon protein 1785810 7685728 SPT_1907 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon protein YP_002743257.1 1785496 D 487213 CDS YP_002743258.1 225861749 7686036 1785829..1786212 1 NC_012469.1 identified by match to protein family HMM PF06125; conjugative transposon protein 1786212 7686036 SPT_1908 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon protein YP_002743258.1 1785829 D 487213 CDS YP_002743259.1 225861750 7686874 1786241..1787626 1 NC_012469.1 identified by match to protein family HMM PF01580; ftsk/spoiiie family protein 1787626 7686874 SPT_1909 Streptococcus pneumoniae Taiwan19F-14 ftsk/spoiiie family protein YP_002743259.1 1786241 D 487213 CDS YP_002743260.1 225861751 7687098 1787804..1789009 1 NC_012469.1 identified by match to protein family HMM PF01381; match to protein family HMM PF02486; transcriptional regulator, Cro/CI family 1789009 7687098 SPT_1910 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, Cro/CI family YP_002743260.1 1787804 D 487213 CDS YP_002743261.1 225861752 7685447 1789052..1789273 1 NC_012469.1 hypothetical protein 1789273 7685447 SPT_1911 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743261.1 1789052 D 487213 CDS YP_002743262.1 225861753 7686699 1789390..1789887 1 NC_012469.1 identified by match to protein family HMM PF07275; conjugative transposon protein 1789887 7686699 SPT_1912 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon protein YP_002743262.1 1789390 D 487213 CDS YP_002743263.1 225861754 7687290 1789862..1790368 1 NC_012469.1 conjugative transposon membrane protein 1790368 7687290 SPT_1913 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon membrane protein YP_002743263.1 1789862 D 487213 CDS YP_002743264.1 225861755 7685397 1790352..1792799 1 NC_012469.1 conjugative transposon protein 1792799 7685397 SPT_1914 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon protein YP_002743264.1 1790352 D 487213 CDS YP_002743265.1 225861756 7685240 1792802..1794979 1 NC_012469.1 conjugative transposon membrane protein 1794979 7685240 SPT_1915 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon membrane protein YP_002743265.1 1792802 D 487213 CDS YP_002743266.1 225861757 7685314 1794976..1795977 1 NC_012469.1 identified by match to protein family HMM PF00877; NLP/P60 family protein 1795977 7685314 SPT_1916 Streptococcus pneumoniae Taiwan19F-14 NLP/P60 family protein YP_002743266.1 1794976 D 487213 CDS YP_002743267.1 225861758 7686810 1795974..1796906 1 NC_012469.1 conjugative transposon protein 1796906 7686810 SPT_1917 Streptococcus pneumoniae Taiwan19F-14 conjugative transposon protein YP_002743267.1 1795974 D 487213 CDS YP_002743268.1 225861759 7687281 1797181..1797267 1 NC_012469.1 regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide 1797267 7687281 SPT_1918 Streptococcus pneumoniae Taiwan19F-14 tetracycline resistance determinant leader peptide YP_002743268.1 1797181 D 487213 CDS YP_002743269.1 225861760 7687252 1797283..1799202 1 NC_012469.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231; tetracycline resistance protein 1799202 7687252 SPT_1919 Streptococcus pneumoniae Taiwan19F-14 tetracycline resistance protein YP_002743269.1 1797283 D 487213 CDS YP_002743270.1 225861761 7686046 1799808..1800143 1 NC_012469.1 hypothetical protein 1800143 7686046 SPT_1922 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743270.1 1799808 D 487213 CDS YP_002743271.1 225861762 7686913 1800213..1800524 1 NC_012469.1 hypothetical protein 1800524 7686913 SPT_1923 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743271.1 1800213 D 487213 CDS YP_002743272.1 225861763 7686263 1800511..1800810 1 NC_012469.1 hypothetical protein 1800810 7686263 SPT_1924 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743272.1 1800511 D 487213 CDS YP_002743273.1 225861764 7685970 complement(1800928..1802391) 1 NC_012469.1 identified by match to protein family HMM PF00005; Mel protein 1802391 7685970 SPT_1925 Streptococcus pneumoniae Taiwan19F-14 Mel protein YP_002743273.1 1800928 R 487213 CDS YP_002743274.1 225861765 7685502 complement(1802511..1803728) 1 NC_012469.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00900; macrolide-efflux protein 1803728 7685502 SPT_1926 Streptococcus pneumoniae Taiwan19F-14 macrolide-efflux protein YP_002743274.1 1802511 R 487213 CDS YP_002743275.1 225861766 7686216 complement(1804114..1804284) 1 NC_012469.1 hypothetical protein 1804284 7686216 SPT_1927 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743275.1 1804114 R 487213 CDS YP_002743276.1 225861767 7687105 complement(1805057..1805410) 1 NC_012469.1 identified by match to protein family HMM PF01381; transcriptional regulator, putative 1805410 7687105 SPT_1928 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, putative YP_002743276.1 1805057 R 487213 CDS YP_002743277.1 225861768 7686843 1805915..1806337 1 NC_012469.1 identified by match to protein family HMM PF04545; match to protein family HMM PF08281; sigma-70, region 4 family 1806337 7686843 SPT_1929 Streptococcus pneumoniae Taiwan19F-14 sigma-70, region 4 family YP_002743277.1 1805915 D 487213 CDS YP_002743278.1 225861769 7687192 1807025..1807228 1 NC_012469.1 identified by match to protein family HMM PF09035; hypothetical protein 1807228 7687192 SPT_1930 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743278.1 1807025 D 487213 CDS YP_002743279.1 225861770 7686825 1807310..1808527 1 NC_012469.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02920; transposase 1808527 7686825 SPT_1931 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743279.1 1807310 D 487213 CDS YP_002743280.1 225861771 7685968 1808877..1809017 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1809017 7685968 SPT_1932 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743280.1 1808877 D 487213 CDS YP_002743281.1 225861772 7685745 1809418..1811433 1 NC_012469.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 1811433 7685745 SPT_1933 Streptococcus pneumoniae Taiwan19F-14 bacteriocin-associated integral membrane protein YP_002743281.1 1809418 D 487213 CDS YP_002743282.1 225861773 7686203 1811435..1812067 1 NC_012469.1 identified by match to protein family HMM PF00005; antimicrobial peptide ABC transporter ATPase 1812067 7686203 SPT_1934 Streptococcus pneumoniae Taiwan19F-14 antimicrobial peptide ABC transporter ATPase YP_002743282.1 1811435 D 487213 CDS YP_002743283.1 225861774 7686850 1812208..1812369 1 NC_012469.1 hypothetical protein 1812369 7686850 SPT_1935 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743283.1 1812208 D 487213 CDS YP_002743284.1 225861775 7686298 complement(1812995..1813408) 1 NC_012469.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1813408 ndk 7686298 ndk Streptococcus pneumoniae Taiwan19F-14 nucleoside diphosphate kinase YP_002743284.1 1812995 R 487213 CDS YP_002743285.1 225861776 7686821 complement(1813519..1817196) 1 NC_012469.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1817196 rpoC 7686821 rpoC Streptococcus pneumoniae Taiwan19F-14 DNA-directed RNA polymerase subunit beta' YP_002743285.1 1813519 R 487213 CDS YP_002743286.1 225861777 7686402 complement(1817229..1820840) 1 NC_012469.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1820840 rpoB 7686402 rpoB Streptococcus pneumoniae Taiwan19F-14 DNA-directed RNA polymerase subunit beta YP_002743286.1 1817229 R 487213 CDS YP_002743287.1 225861778 7685439 1820969..1821085 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1821085 7685439 SPT_1939 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743287.1 1820969 D 487213 CDS YP_002743288.1 225861779 7685601 complement(1821343..1821462) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1821462 7685601 SPT_1941 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743288.1 1821343 R 487213 CDS YP_002743289.1 225861780 7685754 complement(1821524..1822855) 1 NC_012469.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain protein 1822855 7685754 SPT_1942 Streptococcus pneumoniae Taiwan19F-14 CBS domain protein YP_002743289.1 1821524 R 487213 CDS YP_002743290.1 225861781 7685921 complement(1823146..1823970) 1 NC_012469.1 identified by match to protein family HMM PF01223; DNA-entry nuclease (Competence-specific nuclease) 1823970 7685921 SPT_1943 Streptococcus pneumoniae Taiwan19F-14 DNA-entry nuclease (Competence-specific nuclease) YP_002743290.1 1823146 R 487213 CDS YP_002743291.1 225861782 7685886 complement(1824009..1824197) 1 NC_012469.1 hypothetical protein 1824197 7685886 SPT_1944 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743291.1 1824009 R 487213 CDS YP_002743292.1 225861783 7686749 complement(1824190..1825473) 1 NC_012469.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1825473 murA 7686749 murA Streptococcus pneumoniae Taiwan19F-14 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002743292.1 1824190 R 487213 CDS YP_002743293.1 225861784 7685680 complement(1825497..1825628) 1 NC_012469.1 hypothetical protein 1825628 7685680 SPT_1946 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743293.1 1825497 R 487213 CDS YP_002743294.1 225861785 7687124 complement(1825785..1826822) 1 NC_012469.1 ATP-dependent protease La 1826822 7687124 SPT_1947 Streptococcus pneumoniae Taiwan19F-14 ATP-dependent protease La YP_002743294.1 1825785 R 487213 CDS YP_002743295.1 225861786 7686705 complement(1826806..1827294) 1 NC_012469.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1827294 coaD 7686705 coaD Streptococcus pneumoniae Taiwan19F-14 phosphopantetheine adenylyltransferase YP_002743295.1 1826806 R 487213 CDS YP_002743296.1 225861787 7685474 complement(1827284..1827823) 1 NC_012469.1 identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; RNA methyltransferase, RsmD family 1827823 rsmD 7685474 rsmD Streptococcus pneumoniae Taiwan19F-14 RNA methyltransferase, RsmD family YP_002743296.1 1827284 R 487213 CDS YP_002743297.1 225861788 7686487 complement(1827888..1828880) 1 NC_012469.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 1828880 asnA 7686487 asnA Streptococcus pneumoniae Taiwan19F-14 asparagine synthetase AsnA YP_002743297.1 1827888 R 487213 CDS YP_002743298.1 225861789 7686181 1828854..1828985 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1828985 7686181 SPT_1951 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743298.1 1828854 D 487213 CDS YP_002743299.1 225861790 7686108 complement(1828991..1829674) 1 NC_012469.1 identified by match to protein family HMM PF01027; membrane protein 1829674 7686108 SPT_1952 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002743299.1 1828991 R 487213 CDS YP_002743300.1 225861791 7686309 complement(1829730..1830470) 1 NC_012469.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032; SpoU rRNA Methylase family protein 1830470 7686309 SPT_1953 Streptococcus pneumoniae Taiwan19F-14 SpoU rRNA Methylase family protein YP_002743300.1 1829730 R 487213 CDS YP_002743301.1 225861792 7686939 1830504..1830782 1 NC_012469.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1830782 7686939 SPT_1954 Streptococcus pneumoniae Taiwan19F-14 acylphosphatase YP_002743301.1 1830504 D 487213 CDS YP_002743302.1 225861793 7685285 1830860..1831786 1 NC_012469.1 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1831786 7685285 SPT_1955 Streptococcus pneumoniae Taiwan19F-14 OxaA-like protein precursor YP_002743302.1 1830860 D 487213 CDS YP_002743303.1 225861794 7685775 complement(1831861..1832655) 1 NC_012469.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493; pyruvate formate-lyase 1-activating enzyme 1832655 pflA 7685775 pflA Streptococcus pneumoniae Taiwan19F-14 pyruvate formate-lyase 1-activating enzyme YP_002743303.1 1831861 R 487213 CDS YP_002743304.1 225861795 7686045 complement(1832781..1834031) 1 NC_012469.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; diaminopimelate decarboxylase 1834031 7686045 SPT_1957 Streptococcus pneumoniae Taiwan19F-14 diaminopimelate decarboxylase YP_002743304.1 1832781 R 487213 CDS YP_002743305.1 225861796 7686901 complement(1834098..1834925) 1 NC_012469.1 identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743; pur operon repressor 1834925 purR 7686901 purR Streptococcus pneumoniae Taiwan19F-14 pur operon repressor YP_002743305.1 1834098 R 487213 CDS YP_002743306.1 225861797 7687107 complement(1835192..1836133) 1 NC_012469.1 identified by match to protein family HMM PF01336; match to protein family HMM PF01966; 3'-5' exoribonuclease YhaM 1836133 7687107 SPT_1959 Streptococcus pneumoniae Taiwan19F-14 3'-5' exoribonuclease YhaM YP_002743306.1 1835192 R 487213 CDS YP_002743307.1 225861798 7686520 complement(1836123..1837379) 1 NC_012469.1 identified by match to protein family HMM PF02646; competence-induced protein Ccs50 1837379 7686520 SPT_1960 Streptococcus pneumoniae Taiwan19F-14 competence-induced protein Ccs50 YP_002743307.1 1836123 R 487213 CDS YP_002743308.1 225861799 7686225 complement(1837381..1838043) 1 NC_012469.1 identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378; thiamine pyrophosphokinase 1838043 7686225 SPT_1961 Streptococcus pneumoniae Taiwan19F-14 thiamine pyrophosphokinase YP_002743308.1 1837381 R 487213 CDS YP_002743309.1 225861800 7686171 complement(1838006..1838662) 1 NC_012469.1 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase 1838662 rpe 7686171 rpe Streptococcus pneumoniae Taiwan19F-14 ribulose-phosphate 3-epimerase YP_002743309.1 1838006 R 487213 CDS YP_002743310.1 225861801 7686450 complement(1838673..1839551) 1 NC_012469.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 1839551 rsgA 7686450 rsgA Streptococcus pneumoniae Taiwan19F-14 ribosome-associated GTPase YP_002743310.1 1838673 R 487213 CDS YP_002743311.1 225861802 7686370 complement(1839553..1840425) 1 NC_012469.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 1840425 ksgA 7686370 ksgA Streptococcus pneumoniae Taiwan19F-14 dimethyladenosine transferase YP_002743311.1 1839553 R 487213 CDS YP_002743312.1 225861803 7686961 complement(1840676..1840792) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1840792 7686961 SPT_1965 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743312.1 1840676 R 487213 CDS YP_002743313.1 225861804 7686109 complement(1840811..1840969) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1840969 7686109 SPT_1966 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743313.1 1840811 R 487213 CDS YP_002743314.1 225861805 7685835 complement(1840962..1841603) 1 NC_012469.1 identified by match to protein family HMM PF00005; antimicrobial peptide ABC transporter ATPase 1841603 7685835 SPT_1967 Streptococcus pneumoniae Taiwan19F-14 antimicrobial peptide ABC transporter ATPase YP_002743314.1 1840962 R 487213 CDS YP_002743315.1 225861806 7685836 complement(1841605..1843635) 1 NC_012469.1 identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; immunity protein, putative 1843635 7685836 SPT_1968 Streptococcus pneumoniae Taiwan19F-14 immunity protein, putative YP_002743315.1 1841605 R 487213 CDS YP_002743316.1 225861807 7686505 complement(1843903..1844802) 1 NC_012469.1 transcriptional activator 1844802 7686505 SPT_1969 Streptococcus pneumoniae Taiwan19F-14 transcriptional activator YP_002743316.1 1843903 R 487213 CDS YP_002743317.1 225861808 7687309 complement(1844874..1845434) 1 NC_012469.1 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; putative primase homolog 1845434 7687309 SPT_1970 Streptococcus pneumoniae Taiwan19F-14 putative primase homolog YP_002743317.1 1844874 R 487213 CDS YP_002743318.1 225861809 7686893 complement(1845434..1846207) 1 NC_012469.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; putative deoxyribonuclease YcfH 1846207 7686893 SPT_1971 Streptococcus pneumoniae Taiwan19F-14 putative deoxyribonuclease YcfH YP_002743318.1 1845434 R 487213 CDS YP_002743319.1 225861810 7686597 complement(1846512..1847516) 1 NC_012469.1 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167; cell wall surface anchor family protein 1847516 7686597 SPT_1972 Streptococcus pneumoniae Taiwan19F-14 cell wall surface anchor family protein YP_002743319.1 1846512 R 487213 CDS YP_002743320.1 225861811 7686748 complement(1847689..1847823) 1 NC_012469.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1847823 rpmH 7686748 rpmH Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L34 YP_002743320.1 1847689 R 487213 CDS YP_002743321.1 225861812 7685426 complement(1847968..1849182) 1 NC_012469.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 1849182 7685426 SPT_1974 Streptococcus pneumoniae Taiwan19F-14 aminotransferase AlaT YP_002743321.1 1847968 R 487213 CDS YP_002743322.1 225861813 7686346 complement(1849373..1849630) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1849630 7686346 SPT_1975 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743322.1 1849373 R 487213 CDS YP_002743323.1 225861814 7685705 1849792..1850244 1 NC_012469.1 identified by match to protein family HMM PF00582; universal stress protein family 1850244 7685705 SPT_1976 Streptococcus pneumoniae Taiwan19F-14 universal stress protein family YP_002743323.1 1849792 D 487213 CDS YP_002743324.1 225861815 7685513 complement(1850279..1851667) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1851667 7685513 SPT_1977 Streptococcus pneumoniae Taiwan19F-14 Cof family protein YP_002743324.1 1850279 R 487213 CDS YP_002743325.1 225861816 7685419 1851733..1852695 1 NC_012469.1 identified by match to protein family HMM PF00710; L-asparaginase 1852695 7685419 SPT_1978 Streptococcus pneumoniae Taiwan19F-14 L-asparaginase YP_002743325.1 1851733 D 487213 CDS YP_002743326.1 225861817 7686414 complement(1852724..1852972) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1852972 7686414 SPT_1979 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743326.1 1852724 R 487213 CDS YP_002743327.1 225861818 7685361 complement(1853036..1854046) 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481; catabolite control protein A 1854046 ccpA 7685361 ccpA Streptococcus pneumoniae Taiwan19F-14 catabolite control protein A YP_002743327.1 1853036 R 487213 CDS YP_002743328.1 225861819 7685978 complement(1854471..1855070) 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; response regulator 1855070 7685978 SPT_1981 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002743328.1 1854471 R 487213 CDS YP_002743329.1 225861820 7685819 complement(1855072..1856169) 1 NC_012469.1 identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 1856169 7685819 SPT_1982 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002743329.1 1855072 R 487213 CDS YP_002743330.1 225861821 7686537 complement(1856169..1856936) 1 NC_012469.1 multidrug ABC transporter permease 1856936 7686537 SPT_1983 Streptococcus pneumoniae Taiwan19F-14 multidrug ABC transporter permease YP_002743330.1 1856169 R 487213 CDS YP_002743331.1 225861822 7687062 complement(1856908..1857792) 1 NC_012469.1 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1857792 7687062 SPT_1984 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein YP_002743331.1 1856908 R 487213 CDS YP_002743332.1 225861823 7685633 complement(1857779..1857973) 1 NC_012469.1 hypothetical protein 1857973 7685633 SPT_1985 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743332.1 1857779 R 487213 CDS YP_002743333.1 225861824 7685950 complement(1857970..1858176) 1 NC_012469.1 hypothetical protein 1858176 7685950 SPT_1986 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743333.1 1857970 R 487213 CDS YP_002743334.1 225861825 7685324 1858649..1859995 1 NC_012469.1 identified by match to protein family HMM PF01609; Spn1 transposase 1859995 7685324 SPT_1987 Streptococcus pneumoniae Taiwan19F-14 Spn1 transposase YP_002743334.1 1858649 D 487213 CDS YP_002743335.1 225861826 7685599 complement(1866564..1867043) 1 NC_012469.1 competence-specific global transcription modulator 1867043 7685599 SPT_2002 Streptococcus pneumoniae Taiwan19F-14 competence-specific global transcription modulator YP_002743335.1 1866564 R 487213 CDS YP_002743336.1 225861827 7687297 complement(1867165..1867701) 1 NC_012469.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1867701 nusG 7687297 nusG Streptococcus pneumoniae Taiwan19F-14 transcription antitermination protein NusG YP_002743336.1 1867165 R 487213 CDS YP_002743337.1 225861828 7686707 complement(1867756..1867932) 1 NC_012469.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1867932 secE 7686707 secE Streptococcus pneumoniae Taiwan19F-14 preprotein translocase subunit SecE YP_002743337.1 1867756 R 487213 CDS YP_002743338.1 225861829 7687076 complement(1867942..1868094) 1 NC_012469.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 1868094 rpmG 7687076 rpmG Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L33 YP_002743338.1 1867942 R 487213 CDS YP_002743339.1 225861830 7685945 complement(1868147..1870342) 1 NC_012469.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 2A 1870342 7685945 SPT_2006 Streptococcus pneumoniae Taiwan19F-14 penicillin-binding protein 2A YP_002743339.1 1868147 R 487213 CDS YP_002743340.1 225861831 7686697 1870468..1871304 1 NC_012469.1 identified by match to protein family HMM PF00849; ribosomal large subunit pseudouridine synthase, RluD subfamily 1871304 7686697 SPT_2007 Streptococcus pneumoniae Taiwan19F-14 ribosomal large subunit pseudouridine synthase, RluD subfamily YP_002743340.1 1870468 D 487213 CDS YP_002743341.1 225861832 7686485 complement(1871373..1872380) 1 NC_012469.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase, type I 1872380 gap 7686485 gap Streptococcus pneumoniae Taiwan19F-14 glyceraldehyde-3-phosphate dehydrogenase, type I YP_002743341.1 1871373 R 487213 CDS YP_002743342.1 225861833 7686664 complement(1872560..1873522) 1 NC_012469.1 identified by match to protein family HMM PF02687; efflux ABC transporter, permease protein 1873522 7686664 SPT_2009 Streptococcus pneumoniae Taiwan19F-14 efflux ABC transporter, permease protein YP_002743342.1 1872560 R 487213 CDS YP_002743343.1 225861834 7685965 complement(1873545..1873673) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1873673 7685965 SPT_2010 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743343.1 1873545 R 487213 CDS YP_002743344.1 225861835 7685817 1873813..1874061 1 NC_012469.1 hypothetical protein 1874061 7685817 SPT_2011 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743344.1 1873813 D 487213 CDS YP_002743345.1 225861836 7686372 complement(1874100..1874429) 1 NC_012469.1 identified by match to protein family HMM PF01710; transposase 1874429 7686372 SPT_2012 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743345.1 1874100 R 487213 CDS YP_002743346.1 225861837 7686989 complement(1874560..1875432) 1 NC_012469.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 1875432 nadC 7686989 nadC Streptococcus pneumoniae Taiwan19F-14 nicotinate-nucleotide pyrophosphorylase YP_002743346.1 1874560 R 487213 CDS YP_002743347.1 225861838 7686616 1875669..1876979 1 NC_012469.1 identified by match to protein family HMM PF03600; match to protein family HMM PF07158; membrane protein 1876979 7686616 SPT_2014 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002743347.1 1875669 D 487213 CDS YP_002743348.1 225861839 7685650 complement(1877345..1877476) 1 NC_012469.1 hypothetical protein 1877476 7685650 SPT_2015 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743348.1 1877345 R 487213 CDS YP_002743349.1 225861840 7687012 complement(1877999..1878727) 1 NC_012469.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 1878727 7687012 SPT_2016 Streptococcus pneumoniae Taiwan19F-14 GntR family transcriptional regulator YP_002743349.1 1877999 R 487213 CDS YP_002743350.1 225861841 7687386 1878885..1880294 1 NC_012469.1 identified by match to protein family HMM PF00232; beta-glucosidase 1880294 7687386 SPT_2017 Streptococcus pneumoniae Taiwan19F-14 beta-glucosidase YP_002743350.1 1878885 D 487213 CDS YP_002743351.1 225861842 7686313 1880312..1881607 1 NC_012469.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; phosphotransferase system system, cellobiose-specific IIC component 1881607 7686313 SPT_2018 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system system, cellobiose-specific IIC component YP_002743351.1 1880312 D 487213 CDS YP_002743352.1 225861843 7685977 1881612..1881920 1 NC_012469.1 identified by match to protein family HMM PF02302; lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) 1881920 7685977 SPT_2019 Streptococcus pneumoniae Taiwan19F-14 lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) YP_002743352.1 1881612 D 487213 CDS YP_002743353.1 225861844 7685348 1881917..1882225 1 NC_012469.1 identified by match to protein family HMM PF02255; lichenan-specific phosphotransferase enzyme iia component (pts system lichenan-specific eiia component) (eiia-lic) (eiii-lic) 1882225 7685348 SPT_2020 Streptococcus pneumoniae Taiwan19F-14 lichenan-specific phosphotransferase enzyme iia component (pts system lichenan-specific eiia component) (eiia-lic) (eiii-lic) YP_002743353.1 1881917 D 487213 CDS YP_002743354.1 225861845 7687380 complement(1883211..1885862) 1 NC_012469.1 identified by match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1885862 7687380 SPT_2021 Streptococcus pneumoniae Taiwan19F-14 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002743354.1 1883211 R 487213 CDS YP_002743355.1 225861846 7687272 complement(1886162..1886572) 1 NC_012469.1 identified by match to protein family HMM PF02493; morn motif family protein 1886572 7687272 SPT_2022 Streptococcus pneumoniae Taiwan19F-14 morn motif family protein YP_002743355.1 1886162 R 487213 CDS YP_002743356.1 225861847 7685768 complement(1886574..1887002) 1 NC_012469.1 identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 1887002 7685768 SPT_2023 Streptococcus pneumoniae Taiwan19F-14 phosphotyrosine protein phosphatase YP_002743356.1 1886574 R 487213 CDS YP_002743357.1 225861848 7685207 complement(1887048..1887347) 1 NC_012469.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 1887347 yajC 7685207 yajC Streptococcus pneumoniae Taiwan19F-14 preprotein translocase subunit YajC YP_002743357.1 1887048 R 487213 CDS YP_002743358.1 225861849 7686425 complement(1887464..1889440) 1 NC_012469.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1889440 tkt2 7686425 tkt2 Streptococcus pneumoniae Taiwan19F-14 transketolase YP_002743358.1 1887464 R 487213 CDS YP_002743359.1 225861850 7687284 complement(1889554..1890645) 1 NC_012469.1 putative L-ascorbate 6-phosphate lactonase 1890645 7687284 SPT_2026 Streptococcus pneumoniae Taiwan19F-14 putative L-ascorbate 6-phosphate lactonase YP_002743359.1 1889554 R 487213 CDS YP_002743360.1 225861851 7685751 complement(1890757..1892430) 1 NC_012469.1 identified by match to protein family HMM PF00874; match to protein family HMM PF08279; transcriptional regulator, BglG family 1892430 7685751 SPT_2027 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, BglG family YP_002743360.1 1890757 R 487213 CDS YP_002743361.1 225861852 7685789 complement(1892611..1893315) 1 NC_012469.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase 1893315 araD 7685789 araD Streptococcus pneumoniae Taiwan19F-14 L-ribulose-5-phosphate 4-epimerase YP_002743361.1 1892611 R 487213 CDS YP_002743362.1 225861853 7687051 complement(1893317..1894180) 1 NC_012469.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 1894180 7687051 SPT_2029 Streptococcus pneumoniae Taiwan19F-14 putative L-xylulose 5-phosphate 3-epimerase YP_002743362.1 1893317 R 487213 CDS YP_002743363.1 225861854 7685209 complement(1894184..1894849) 1 NC_012469.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 1894849 ulaD 7685209 ulaD Streptococcus pneumoniae Taiwan19F-14 3-keto-L-gulonate-6-phosphate decarboxylase YP_002743363.1 1894184 R 487213 CDS YP_002743364.1 225861855 7686615 complement(1894866..1895351) 1 NC_012469.1 identified by match to protein family HMM PF00359; ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component) 1895351 7686615 SPT_2031 Streptococcus pneumoniae Taiwan19F-14 ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component) YP_002743364.1 1894866 R 487213 CDS YP_002743365.1 225861856 7685672 complement(1895427..1895708) 1 NC_012469.1 identified by match to protein family HMM PF02302; ascorbate-specific phosphotransferase enzyme iib component (ascorbate-specific pts system eiib component) 1895708 7685672 SPT_2032 Streptococcus pneumoniae Taiwan19F-14 ascorbate-specific phosphotransferase enzyme iib component (ascorbate-specific pts system eiib component) YP_002743365.1 1895427 R 487213 CDS YP_002743366.1 225861857 7686337 complement(1895731..1897188) 1 NC_012469.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1897188 7686337 SPT_2033 Streptococcus pneumoniae Taiwan19F-14 PTS system ascorbate-specific transporter subunit IIC YP_002743366.1 1895731 R 487213 CDS YP_002743367.1 225861858 7687352 complement(1897317..1897940) 1 NC_012469.1 hypothetical protein 1897940 7687352 SPT_2034 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743367.1 1897317 R 487213 CDS YP_002743368.1 225861859 7685923 complement(1897991..1898977) 1 NC_012469.1 identified by match to protein family HMM PF01424; jag protein 1898977 7685923 SPT_2035 Streptococcus pneumoniae Taiwan19F-14 jag protein YP_002743368.1 1897991 R 487213 CDS YP_002743369.1 225861860 7685709 complement(1898996..1899769) 1 NC_012469.1 identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592; membrane protein OxaA 1 1899769 7685709 SPT_2036 Streptococcus pneumoniae Taiwan19F-14 membrane protein OxaA 1 YP_002743369.1 1898996 R 487213 CDS YP_002743370.1 225861861 7687241 complement(1899795..1900166) 1 NC_012469.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1900166 rnpA 7687241 rnpA Streptococcus pneumoniae Taiwan19F-14 ribonuclease P YP_002743370.1 1899795 R 487213 CDS YP_002743371.1 225861862 7686244 complement(1900183..1900314) 1 NC_012469.1 hypothetical protein 1900314 7686244 SPT_2038 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743371.1 1900183 R 487213 CDS YP_002743372.1 225861863 7686115 complement(1900315..1901505) 1 NC_012469.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1901505 ackA 7686115 ackA Streptococcus pneumoniae Taiwan19F-14 acetate kinase YP_002743372.1 1900315 R 487213 CDS YP_002743373.1 225861864 7686427 complement(1901556..1902509) 1 NC_012469.1 adenine-specific DNA methylase 1902509 7686427 SPT_2040 Streptococcus pneumoniae Taiwan19F-14 adenine-specific DNA methylase YP_002743373.1 1901556 R 487213 CDS YP_002743374.1 225861865 7687239 complement(1902570..1903157) 1 NC_012469.1 identified by match to protein family HMM PF01209; match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; methyltransferase small domain superfamily 1903157 7687239 SPT_2041 Streptococcus pneumoniae Taiwan19F-14 methyltransferase small domain superfamily YP_002743374.1 1902570 R 487213 CDS YP_002743375.1 225861866 7686625 complement(1903294..1903707) 1 NC_012469.1 hypothetical protein 1903707 7686625 SPT_2042 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743375.1 1903294 R 487213 CDS YP_002743376.1 225861867 7686022 complement(1903685..1904146) 1 NC_012469.1 competence protein ComGF 1904146 7686022 SPT_2043 Streptococcus pneumoniae Taiwan19F-14 competence protein ComGF YP_002743376.1 1903685 R 487213 CDS YP_002743377.1 225861868 7687046 complement(1904109..1904369) 1 NC_012469.1 hypothetical protein 1904369 7687046 SPT_2044 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743377.1 1904109 R 487213 CDS YP_002743378.1 225861869 7687127 complement(1904374..1904778) 1 NC_012469.1 identified by match to protein family HMM TIGR02532; competence protein CglD 1904778 7687127 SPT_2045 Streptococcus pneumoniae Taiwan19F-14 competence protein CglD YP_002743378.1 1904374 R 487213 CDS YP_002743379.1 225861870 7686604 complement(1904771..1905097) 1 NC_012469.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; competence protein 1905097 7686604 SPT_2046 Streptococcus pneumoniae Taiwan19F-14 competence protein YP_002743379.1 1904771 R 487213 CDS YP_002743380.1 225861871 7685690 complement(1905099..1905971) 1 NC_012469.1 identified by match to protein family HMM PF00482; competence protein CglB 1905971 7685690 SPT_2047 Streptococcus pneumoniae Taiwan19F-14 competence protein CglB YP_002743380.1 1905099 R 487213 CDS YP_002743381.1 225861872 7686847 complement(1906063..1907004) 1 NC_012469.1 identified by match to protein family HMM PF00437; putative ABC transporter subunit ComYA 1907004 7686847 SPT_2048 Streptococcus pneumoniae Taiwan19F-14 putative ABC transporter subunit ComYA YP_002743381.1 1906063 R 487213 CDS YP_002743382.1 225861873 7685821 complement(1907080..1907445) 1 NC_012469.1 identified by match to protein family HMM PF06279; hypothetical protein 1907445 7685821 SPT_2049 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743382.1 1907080 R 487213 CDS YP_002743383.1 225861874 7686983 complement(1907596..1908654) 1 NC_012469.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase, zinc-containing 1908654 7686983 SPT_2050 Streptococcus pneumoniae Taiwan19F-14 alcohol dehydrogenase, zinc-containing YP_002743383.1 1907596 R 487213 CDS YP_002743384.1 225861875 7686377 complement(1908817..1909968) 1 NC_012469.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 1909968 nagA 7686377 nagA Streptococcus pneumoniae Taiwan19F-14 N-acetylglucosamine-6-phosphate deacetylase YP_002743384.1 1908817 R 487213 CDS YP_002743385.1 225861876 7686301 complement(1910121..1911938) 1 NC_012469.1 identified by match to protein family HMM PF01757; acyltransferase 1911938 7686301 SPT_2052 Streptococcus pneumoniae Taiwan19F-14 acyltransferase YP_002743385.1 1910121 R 487213 CDS YP_002743386.1 225861877 7686074 complement(1912039..1913181) 1 NC_012469.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1913181 tgt 7686074 tgt Streptococcus pneumoniae Taiwan19F-14 queuine tRNA-ribosyltransferase YP_002743386.1 1912039 R 487213 CDS YP_002743387.1 225861878 7686217 1913311..1914168 1 NC_012469.1 identified by match to protein family HMM PF06161; hypothetical protein 1914168 7686217 SPT_2054 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743387.1 1913311 D 487213 CDS YP_002743388.1 225861879 7686511 complement(1914196..1914840) 1 NC_012469.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 1914840 pcp2 7686511 pcp2 Streptococcus pneumoniae Taiwan19F-14 pyrrolidone-carboxylate peptidase YP_002743388.1 1914196 R 487213 CDS YP_002743389.1 225861880 7687301 complement(1914915..1915316) 1 NC_012469.1 identified by match to protein family HMM PF06993; hypothetical protein 1915316 7687301 SPT_2056 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743389.1 1914915 R 487213 CDS YP_002743390.1 225861881 7686714 complement(1915327..1915752) 1 NC_012469.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; transcriptional regulator, MarR family 1915752 7686714 SPT_2057 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, MarR family YP_002743390.1 1915327 R 487213 CDS YP_002743391.1 225861882 7686776 complement(1916075..1917217) 1 NC_012469.1 identified by match to protein family HMM PF01476; LysM domain-containing protein 1917217 7686776 SPT_2058 Streptococcus pneumoniae Taiwan19F-14 LysM domain-containing protein YP_002743391.1 1916075 R 487213 CDS YP_002743392.1 225861883 7685879 complement(1917383..1918003) 1 NC_012469.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD-superfamily hydrolase, subfamily IA, variant 1 1918003 7685879 SPT_2059 Streptococcus pneumoniae Taiwan19F-14 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_002743392.1 1917383 R 487213 CDS YP_002743393.1 225861884 7686371 complement(1918007..1919287) 1 NC_012469.1 identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR00797; multi antimicrobial extrusion 1919287 7686371 SPT_2060 Streptococcus pneumoniae Taiwan19F-14 multi antimicrobial extrusion YP_002743393.1 1918007 R 487213 CDS YP_002743394.1 225861885 7685427 complement(1919348..1920832) 1 NC_012469.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1920832 thrC 7685427 thrC Streptococcus pneumoniae Taiwan19F-14 threonine synthase YP_002743394.1 1919348 R 487213 CDS YP_002743395.1 225861886 7686837 complement(1920908..1922185) 1 NC_012469.1 hypothetical protein 1922185 7686837 SPT_2062 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743395.1 1920908 R 487213 CDS YP_002743396.1 225861887 7685586 complement(1928647..1929081) 1 NC_012469.1 cytidine/deoxycytidylate deaminase family protein 1929081 7685586 SPT_2079 Streptococcus pneumoniae Taiwan19F-14 cytidine/deoxycytidylate deaminase family protein YP_002743396.1 1928647 R 487213 CDS YP_002743397.1 225861888 7687328 complement(1929095..1930555) 1 NC_012469.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1930555 gltX 7687328 gltX Streptococcus pneumoniae Taiwan19F-14 glutamyl-tRNA synthetase YP_002743397.1 1929095 R 487213 CDS YP_002743398.1 225861889 7685282 complement(1930679..1932028) 1 NC_012469.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 1932028 pgi 7685282 pgi Streptococcus pneumoniae Taiwan19F-14 glucose-6-phosphate isomerase YP_002743398.1 1930679 R 487213 CDS YP_002743399.1 225861890 7686072 complement(1932015..1932194) 1 NC_012469.1 hypothetical protein 1932194 7686072 SPT_2082 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743399.1 1932015 R 487213 CDS YP_002743400.1 225861891 7685231 complement(1932198..1932887) 1 NC_012469.1 identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase 1932887 7685231 SPT_2083 Streptococcus pneumoniae Taiwan19F-14 glutamine amidotransferase YP_002743400.1 1932198 R 487213 CDS YP_002743401.1 225861892 7686669 complement(1933026..1934792) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1934792 7686669 SPT_2084 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein/permease YP_002743401.1 1933026 R 487213 CDS YP_002743402.1 225861893 7687315 1934939..1935253 1 NC_012469.1 transposase 1935253 7687315 SPT_2085 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743402.1 1934939 D 487213 CDS YP_002743403.1 225861894 7686431 complement(1935584..1937278) 1 NC_012469.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 1937278 7686431 SPT_2086 Streptococcus pneumoniae Taiwan19F-14 ABC transporter ATP-binding protein/permease YP_002743403.1 1935584 R 487213 CDS YP_002743404.1 225861895 7686656 complement(1937424..1939958) 1 NC_012469.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1939958 mutS 7686656 mutS Streptococcus pneumoniae Taiwan19F-14 DNA mismatch repair protein MutS YP_002743404.1 1937424 R 487213 CDS YP_002743405.1 225861896 7686210 complement(1940009..1940455) 1 NC_012469.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529; arginine repressor 1940455 argR 7686210 argR Streptococcus pneumoniae Taiwan19F-14 arginine repressor YP_002743405.1 1940009 R 487213 CDS YP_002743406.1 225861897 7685475 1940591..1942282 1 NC_012469.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1942282 argS 7685475 argS Streptococcus pneumoniae Taiwan19F-14 arginyl-tRNA synthetase YP_002743406.1 1940591 D 487213 CDS YP_002743407.1 225861898 7685275 complement(1942597..1942986) 1 NC_012469.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 1942986 7685275 SPT_2090 Streptococcus pneumoniae Taiwan19F-14 transposase (IS4 family) YP_002743407.1 1942597 R 487213 CDS YP_002743408.1 225861899 7687193 1943140..1943625 1 NC_012469.1 identified by match to protein family HMM PF06172; hypothetical protein 1943625 7687193 SPT_2091 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743408.1 1943140 D 487213 CDS YP_002743409.1 225861900 7686381 1943709..1944416 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 1944416 7686381 SPT_2092 Streptococcus pneumoniae Taiwan19F-14 alkaline phosphatase synthesis transcriptional regulatory proteinphoP YP_002743409.1 1943709 D 487213 CDS YP_002743410.1 225861901 7686334 1944417..1945748 1 NC_012469.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; histidine kinase PnpS 1945748 7686334 SPT_2093 Streptococcus pneumoniae Taiwan19F-14 histidine kinase PnpS YP_002743410.1 1944417 D 487213 CDS YP_002743411.1 225861902 7686911 1945915..1946790 1 NC_012469.1 ABC transporter substrate-binding protein - phosphate transport 1946790 7686911 SPT_2094 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein - phosphate transport YP_002743411.1 1945915 D 487213 CDS YP_002743412.1 225861903 7686044 1946908..1947771 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 1947771 pstC2 7686044 pstC2 Streptococcus pneumoniae Taiwan19F-14 phosphate ABC transporter permease YP_002743412.1 1946908 D 487213 CDS YP_002743413.1 225861904 7687104 1947764..1948579 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 1948579 pstA2 7687104 pstA2 Streptococcus pneumoniae Taiwan19F-14 phosphate ABC transporter permease YP_002743413.1 1947764 D 487213 CDS YP_002743414.1 225861905 7686904 1948581..1949333 1 NC_012469.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1949333 pstB3 7686904 pstB3 Streptococcus pneumoniae Taiwan19F-14 phosphate transporter ATP-binding protein YP_002743414.1 1948581 D 487213 CDS YP_002743415.1 225861906 7685826 1949348..1949998 1 NC_012469.1 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 1949998 phoU2 7685826 phoU2 Streptococcus pneumoniae Taiwan19F-14 phosphate transport system regulatory protein PhoU YP_002743415.1 1949348 D 487213 CDS YP_002743416.1 225861907 7686123 1950066..1950491 1 NC_012469.1 transposase, IS1380-Spn1 related, truncation 1950491 7686123 SPT_2099 Streptococcus pneumoniae Taiwan19F-14 transposase, IS1380-Spn1 related, truncation YP_002743416.1 1950066 D 487213 CDS YP_002743417.1 225861908 7686646 1951257..1952273 1 NC_012469.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1952273 gpsA 7686646 gpsA Streptococcus pneumoniae Taiwan19F-14 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002743417.1 1951257 D 487213 CDS YP_002743418.1 225861909 7687013 1952295..1953194 1 NC_012469.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 1953194 galU 7687013 galU Streptococcus pneumoniae Taiwan19F-14 UTP-glucose-1-phosphate uridylyltransferase YP_002743418.1 1952295 D 487213 CDS YP_002743419.1 225861910 7685722 complement(1953266..1953943) 1 NC_012469.1 identified by match to protein family HMM PF01694; peptidase, S54 1953943 7685722 SPT_2103 Streptococcus pneumoniae Taiwan19F-14 peptidase, S54 YP_002743419.1 1953266 R 487213 CDS YP_002743420.1 225861911 7686011 complement(1953927..1954466) 1 NC_012469.1 identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5-formyltetrahydrofolate cyclo-ligase 1954466 7686011 SPT_2104 Streptococcus pneumoniae Taiwan19F-14 5-formyltetrahydrofolate cyclo-ligase YP_002743420.1 1953927 R 487213 CDS YP_002743421.1 225861912 7686829 complement(1954478..1955608) 1 NC_012469.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; peptidase, M20/M25/M40 family 1955608 7686829 SPT_2105 Streptococcus pneumoniae Taiwan19F-14 peptidase, M20/M25/M40 family YP_002743421.1 1954478 R 487213 CDS YP_002743422.1 225861913 7686777 complement(1955676..1956374) 1 NC_012469.1 identified by match to protein family HMM PF00132; match to protein family HMM PF08503; galactoside O-acetyltransferase 1956374 7686777 SPT_2106 Streptococcus pneumoniae Taiwan19F-14 galactoside O-acetyltransferase YP_002743422.1 1955676 R 487213 CDS YP_002743423.1 225861914 7685336 complement(1956604..1957515) 1 NC_012469.1 identified by match to protein family HMM PF00892; membrane protein 1957515 7685336 SPT_2107 Streptococcus pneumoniae Taiwan19F-14 membrane protein YP_002743423.1 1956604 R 487213 CDS YP_002743424.1 225861915 7686550 complement(1957580..1960045) 1 NC_012469.1 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; penicillin-binding protein 1B 1960045 7686550 SPT_2108 Streptococcus pneumoniae Taiwan19F-14 penicillin-binding protein 1B YP_002743424.1 1957580 R 487213 CDS YP_002743425.1 225861916 7686283 1960187..1961443 1 NC_012469.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1961443 tyrS 7686283 tyrS Streptococcus pneumoniae Taiwan19F-14 tyrosyl-tRNA synthetase YP_002743425.1 1960187 D 487213 CDS YP_002743426.1 225861917 7686784 complement(1961521..1963584) 1 NC_012469.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525; P-type ATPase-metal/cation transport 1963584 7686784 SPT_2110 Streptococcus pneumoniae Taiwan19F-14 P-type ATPase-metal/cation transport YP_002743426.1 1961521 R 487213 CDS YP_002743427.1 225861918 7685656 complement(1963586..1963864) 1 NC_012469.1 hypothetical protein 1963864 7685656 SPT_2111 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743427.1 1963586 R 487213 CDS YP_002743428.1 225861919 7686980 1964016..1964864 1 NC_012469.1 identified by match to protein family HMM PF08241; 23S rRNA m1G745 methyltransferase 1964864 7686980 SPT_2112 Streptococcus pneumoniae Taiwan19F-14 23S rRNA m1G745 methyltransferase YP_002743428.1 1964016 D 487213 CDS YP_002743429.1 225861920 7686191 complement(1965425..1965631) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1965631 7686191 SPT_2113 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743429.1 1965425 R 487213 CDS YP_002743430.1 225861921 7685434 complement(1966586..1968844) 1 NC_012469.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase 1968844 7685434 SPT_2114 Streptococcus pneumoniae Taiwan19F-14 glycogen phosphorylase YP_002743430.1 1966586 R 487213 CDS YP_002743431.1 225861922 7687214 complement(1968870..1970387) 1 NC_012469.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 1970387 malQ 7687214 malQ Streptococcus pneumoniae Taiwan19F-14 4-alpha-glucanotransferase YP_002743431.1 1968870 R 487213 CDS YP_002743432.1 225861923 7686304 1970937..1972208 1 NC_012469.1 identified by match to protein family HMM PF01547; maltose/maltodextrin-binding protein 1972208 7686304 SPT_2116 Streptococcus pneumoniae Taiwan19F-14 maltose/maltodextrin-binding protein YP_002743432.1 1970937 D 487213 CDS YP_002743433.1 225861924 7686083 1972319..1973611 1 NC_012469.1 identified by match to protein family HMM PF00528; match to protein family HMM PF05154; maltodextrin transport system permease protein MalC 1973611 7686083 SPT_2117 Streptococcus pneumoniae Taiwan19F-14 maltodextrin transport system permease protein MalC YP_002743433.1 1972319 D 487213 CDS YP_002743434.1 225861925 7686957 1973613..1974455 1 NC_012469.1 identified by match to protein family HMM PF00528; maltose/maltodextrin ABC transporter permease 1974455 7686957 SPT_2118 Streptococcus pneumoniae Taiwan19F-14 maltose/maltodextrin ABC transporter permease YP_002743434.1 1973613 D 487213 CDS YP_002743435.1 225861926 7687148 1974708..1975508 1 NC_012469.1 maltodextrose utilization protein MalA 1975508 7687148 SPT_2119 Streptococcus pneumoniae Taiwan19F-14 maltodextrose utilization protein MalA YP_002743435.1 1974708 D 487213 CDS YP_002743436.1 225861927 7686906 1975518..1976504 1 NC_012469.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; HTH-type transcriptional regulator MalR (Maltose operontranscriptional repressor) 1976504 7686906 SPT_2120 Streptococcus pneumoniae Taiwan19F-14 HTH-type transcriptional regulator MalR (Maltose operontranscriptional repressor) YP_002743436.1 1975518 D 487213 CDS YP_002743437.1 225861928 7685490 complement(1976795..1977736) 1 NC_012469.1 identified by match to protein family HMM PF02588; YitT family protein 1977736 7685490 SPT_2121 Streptococcus pneumoniae Taiwan19F-14 YitT family protein YP_002743437.1 1976795 R 487213 CDS YP_002743438.1 225861929 7686213 complement(1977714..1979477) 1 NC_012469.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1979477 aspS 7686213 aspS Streptococcus pneumoniae Taiwan19F-14 aspartyl-tRNA synthetase YP_002743438.1 1977714 R 487213 CDS YP_002743439.1 225861930 7687188 complement(1979596..1979832) 1 NC_012469.1 chlorohydrolase 1979832 7687188 SPT_2123 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002743439.1 1979596 R 487213 CDS YP_002743440.1 225861931 7685942 complement(1979874..1980104) 1 NC_012469.1 hypothetical protein 1980104 7685942 SPT_2124 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743440.1 1979874 R 487213 CDS YP_002743441.1 225861932 7686474 complement(1980122..1980763) 1 NC_012469.1 identified by match to protein family HMM PF02517; caax amino protease family 1980763 7686474 SPT_2125 Streptococcus pneumoniae Taiwan19F-14 caax amino protease family YP_002743441.1 1980122 R 487213 CDS YP_002743442.1 225861933 7687313 complement(1980775..1981509) 1 NC_012469.1 hypothetical protein 1981509 7687313 SPT_2126 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743442.1 1980775 R 487213 CDS YP_002743443.1 225861934 7686715 complement(1981512..1981709) 1 NC_012469.1 hypothetical protein 1981709 7686715 SPT_2127 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743443.1 1981512 R 487213 CDS YP_002743444.1 225861935 7687260 complement(1981709..1981915) 1 NC_012469.1 identified by match to protein family HMM PF01381; hypothetical protein 1981915 7687260 SPT_2128 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743444.1 1981709 R 487213 CDS YP_002743445.1 225861936 7686717 complement(1981925..1982239) 1 NC_012469.1 hypothetical protein 1982239 7686717 SPT_2129 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743445.1 1981925 R 487213 CDS YP_002743446.1 225861937 7685327 complement(1982193..1982345) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1982345 7685327 SPT_2130 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743446.1 1982193 R 487213 CDS YP_002743447.1 225861938 7687056 complement(1982389..1982535) 1 NC_012469.1 chlorohydrolase 1982535 7687056 SPT_2131 Streptococcus pneumoniae Taiwan19F-14 chlorohydrolase YP_002743447.1 1982389 R 487213 CDS YP_002743448.1 225861939 7685785 complement(1982532..1983821) 1 NC_012469.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1983821 hisS 7685785 hisS Streptococcus pneumoniae Taiwan19F-14 histidyl-tRNA synthetase YP_002743448.1 1982532 R 487213 CDS YP_002743449.1 225861940 7686804 complement(1983899..1985146) 1 NC_012469.1 identified by match to protein family HMM PF07690; transporter, major facilitator family 1985146 7686804 SPT_2133 Streptococcus pneumoniae Taiwan19F-14 transporter, major facilitator family YP_002743449.1 1983899 R 487213 CDS YP_002743450.1 225861941 7686806 complement(1985337..1986098) 1 NC_012469.1 identified by match to protein family HMM TIGR01716; positive transcriptional regulator of glucosyltransferase and Spp phenotype 1986098 7686806 SPT_2134 Streptococcus pneumoniae Taiwan19F-14 positive transcriptional regulator of glucosyltransferase and Spp phenotype YP_002743450.1 1985337 R 487213 CDS YP_002743451.1 225861942 7686949 complement(1986163..1986297) 1 NC_012469.1 hypothetical protein 1986297 7686949 SPT_2135 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743451.1 1986163 R 487213 CDS YP_002743452.1 225861943 7686504 1986312..1986653 1 NC_012469.1 identified by match to protein family HMM PF01883; hypothetical protein 1986653 7686504 SPT_2136 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743452.1 1986312 D 487213 CDS YP_002743453.1 225861944 7685843 1986717..1986881 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 1986881 7685843 SPT_2137 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743453.1 1986717 D 487213 CDS YP_002743454.1 225861945 7687354 complement(1986907..1988610) 1 NC_012469.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1988610 ilvD 7687354 ilvD Streptococcus pneumoniae Taiwan19F-14 dihydroxy-acid dehydratase YP_002743454.1 1986907 R 487213 CDS YP_002743455.1 225861946 7685783 complement(1988843..1989775) 1 NC_012469.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase, C- subunit 1989775 7685783 SPT_2139 Streptococcus pneumoniae Taiwan19F-14 transketolase, C- subunit YP_002743455.1 1988843 R 487213 CDS YP_002743456.1 225861947 7686130 complement(1989772..1990629) 1 NC_012469.1 identified by match to protein family HMM PF00456; transketolase, thiamine disphosphate-binding subunit 1990629 7686130 SPT_2140 Streptococcus pneumoniae Taiwan19F-14 transketolase, thiamine disphosphate-binding subunit YP_002743456.1 1989772 R 487213 CDS YP_002743457.1 225861948 7686241 complement(1990633..1991979) 1 NC_012469.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1991979 ulaA 7686241 ulaA Streptococcus pneumoniae Taiwan19F-14 PTS system ascorbate-specific transporter subunit IIC YP_002743457.1 1990633 R 487213 CDS YP_002743458.1 225861949 7685882 complement(1991992..1992276) 1 NC_012469.1 identified by match to protein family HMM PF02302; phosphotransferase system, galactitol-specific IIB component 1992276 7685882 SPT_2142 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system, galactitol-specific IIB component YP_002743458.1 1991992 R 487213 CDS YP_002743459.1 225861950 7686531 complement(1992280..1994310) 1 NC_012469.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; transcriptional regulator, BglG family protein 1994310 7686531 SPT_2143 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator, BglG family protein YP_002743459.1 1992280 R 487213 CDS YP_002743460.1 225861951 7685689 1994501..1995508 1 NC_012469.1 identified by match to protein family HMM PF01145; integral membrane protein 1995508 7685689 SPT_2144 Streptococcus pneumoniae Taiwan19F-14 integral membrane protein YP_002743460.1 1994501 D 487213 CDS YP_002743461.1 225861952 7686822 1995511..1995711 1 NC_012469.1 hypothetical protein 1995711 7686822 SPT_2145 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743461.1 1995511 D 487213 CDS YP_002743462.1 225861953 7687086 1995863..1996045 1 NC_012469.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1996045 rpmF 7687086 rpmF Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L32 YP_002743462.1 1995863 D 487213 CDS YP_002743463.1 225861954 7686918 1996061..1996210 1 NC_012469.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1996210 rpmG 7686918 rpmG Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L33 YP_002743463.1 1996061 D 487213 CDS YP_002743464.1 225861955 7686488 complement(1996690..1998555) 1 NC_012469.1 identified by match to protein family HMM PF01473; choline binding protein PcpA 1998555 7686488 SPT_2148 Streptococcus pneumoniae Taiwan19F-14 choline binding protein PcpA YP_002743464.1 1996690 R 487213 CDS YP_002743465.1 225861956 7685975 1999029..1999250 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1999250 7685975 SPT_2151 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743465.1 1999029 D 487213 CDS YP_002743466.1 225861957 7685350 1999477..1999866 1 NC_012469.1 identified by match to protein family HMM PF01609; transposase (IS4 family) 1999866 7685350 SPT_2152 Streptococcus pneumoniae Taiwan19F-14 transposase (IS4 family) YP_002743466.1 1999477 D 487213 CDS YP_002743467.1 225861958 7685248 complement(1999918..2000193) 1 NC_012469.1 hypothetical protein 2000193 7685248 SPT_2153 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743467.1 1999918 R 487213 CDS YP_002743468.1 225861959 7686408 complement(2000571..2002451) 1 NC_012469.1 identified by match to protein family HMM PF00728; N-acetyl-beta-D-glucosaminidase 2002451 7686408 SPT_2154 Streptococcus pneumoniae Taiwan19F-14 N-acetyl-beta-D-glucosaminidase YP_002743468.1 2000571 R 487213 CDS YP_002743469.1 225861960 7686603 complement(2002445..2003314) 1 NC_012469.1 identified by match to protein family HMM PF00480; ROK family protein 2003314 7686603 SPT_2155 Streptococcus pneumoniae Taiwan19F-14 ROK family protein YP_002743469.1 2002445 R 487213 CDS YP_002743470.1 225861961 7686291 complement(2003398..2006043) 1 NC_012469.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748; glycosyl hydrolase, family 38 2006043 7686291 SPT_2156 Streptococcus pneumoniae Taiwan19F-14 glycosyl hydrolase, family 38 YP_002743470.1 2003398 R 487213 CDS YP_002743471.1 225861962 7686497 complement(2006134..2007414) 1 NC_012469.1 identified by match to protein family HMM PF06824; twin-arginine translocation pathway signal 2007414 7686497 SPT_2157 Streptococcus pneumoniae Taiwan19F-14 twin-arginine translocation pathway signal YP_002743471.1 2006134 R 487213 CDS YP_002743472.1 225861963 7687205 2007585..2009669 1 NC_012469.1 identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180; antigen, cell wall surface anchor family 2009669 7687205 SPT_2158 Streptococcus pneumoniae Taiwan19F-14 antigen, cell wall surface anchor family YP_002743472.1 2007585 D 487213 CDS YP_002743473.1 225861964 7685929 complement(2009709..2011388) 1 NC_012469.1 identified by match to protein family HMM PF00754; putative alpha-L-fucosidase 1 (Alpha-L-fucoside fucohydrolase) 2011388 7685929 SPT_2159 Streptococcus pneumoniae Taiwan19F-14 putative alpha-L-fucosidase 1 (Alpha-L-fucoside fucohydrolase) YP_002743473.1 2009709 R 487213 CDS YP_002743474.1 225861965 7685459 2012144..2013373 1 NC_012469.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2013373 arcA 7685459 arcA Streptococcus pneumoniae Taiwan19F-14 arginine deiminase YP_002743474.1 2012144 D 487213 CDS YP_002743475.1 225861966 7686897 2013431..2014447 1 NC_012469.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2014447 argF 7686897 argF Streptococcus pneumoniae Taiwan19F-14 ornithine carbamoyltransferase YP_002743475.1 2013431 D 487213 CDS YP_002743476.1 225861967 7687384 2014612..2015559 1 NC_012469.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2015559 arcC 7687384 arcC Streptococcus pneumoniae Taiwan19F-14 carbamate kinase YP_002743476.1 2014612 D 487213 CDS YP_002743477.1 225861968 7686237 2015770..2017281 1 NC_012469.1 identified by match to protein family HMM PF03606; arginine-ornithine antiporter 2017281 7686237 SPT_2163 Streptococcus pneumoniae Taiwan19F-14 arginine-ornithine antiporter YP_002743477.1 2015770 D 487213 CDS YP_002743478.1 225861969 7687141 2017303..2018634 1 NC_012469.1 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887; hypothetical protein 2018634 7687141 SPT_2164 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743478.1 2017303 D 487213 CDS YP_002743479.1 225861970 7685724 2018729..2018857 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 2018857 7685724 SPT_2165 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743479.1 2018729 D 487213 CDS YP_002743480.1 225861971 7685270 complement(2019115..2019330) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 2019330 7685270 SPT_2166 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743480.1 2019115 R 487213 CDS YP_002743481.1 225861972 7687176 complement(2019318..2019584) 1 NC_012469.1 identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168; gram-positive signal peptide, ysirk family protein 2019584 7687176 SPT_2167 Streptococcus pneumoniae Taiwan19F-14 gram-positive signal peptide, ysirk family protein YP_002743481.1 2019318 R 487213 CDS YP_002743482.1 225861973 7685623 2019773..2019940 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 2019940 7685623 SPT_2168 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743482.1 2019773 D 487213 CDS YP_002743483.1 225861974 7685792 complement(2019967..2020866) 1 NC_012469.1 identified by match to protein family HMM PF01145; spfh domain/band 7 family 2020866 7685792 SPT_2169 Streptococcus pneumoniae Taiwan19F-14 spfh domain/band 7 family YP_002743483.1 2019967 R 487213 CDS YP_002743484.1 225861975 7685204 complement(2020996..2022147) 1 NC_012469.1 identified by match to protein family HMM PF00465; NAD-dependent methanol dehydrogenase (medh) 2022147 7685204 SPT_2170 Streptococcus pneumoniae Taiwan19F-14 NAD-dependent methanol dehydrogenase (medh) YP_002743484.1 2020996 R 487213 CDS YP_002743485.1 225861976 7686718 complement(2022293..2024059) 1 NC_012469.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2024059 fucI 7686718 fucI Streptococcus pneumoniae Taiwan19F-14 L-fucose isomerase YP_002743485.1 2022293 R 487213 CDS YP_002743486.1 225861977 7686103 complement(2024116..2027034) 1 NC_012469.1 identified by match to protein family HMM PF00754; match to protein family HMM PF08307; glycosyl hydrolase family 98 C- domain protein 2027034 7686103 SPT_2172 Streptococcus pneumoniae Taiwan19F-14 glycosyl hydrolase family 98 C- domain protein YP_002743486.1 2024116 R 487213 CDS YP_002743487.1 225861978 7686089 complement(2027242..2029536) 1 NC_012469.1 large secreted protein 2029536 7686089 SPT_2173 Streptococcus pneumoniae Taiwan19F-14 large secreted protein YP_002743487.1 2027242 R 487213 CDS YP_002743488.1 225861979 7686872 complement(2029595..2030395) 1 NC_012469.1 identified by match to protein family HMM PF03613; mannose permease iid component (pts system mannose-specific eiidcomponent) (eiid-man) (eii-m-man) 2030395 7686872 SPT_2174 Streptococcus pneumoniae Taiwan19F-14 mannose permease iid component (pts system mannose-specific eiidcomponent) (eiid-man) (eii-m-man) YP_002743488.1 2029595 R 487213 CDS YP_002743489.1 225861980 7685849 complement(2030392..2031165) 1 NC_012469.1 identified by match to protein family HMM PF03609; phosphotransferase system sugar-specific EII component 2031165 7685849 SPT_2175 Streptococcus pneumoniae Taiwan19F-14 phosphotransferase system sugar-specific EII component YP_002743489.1 2030392 R 487213 CDS YP_002743490.1 225861981 7687336 complement(2031190..2031660) 1 NC_012469.1 identified by match to protein family HMM PF03830; PTS system, IIB component 2031660 7687336 SPT_2176 Streptococcus pneumoniae Taiwan19F-14 PTS system, IIB component YP_002743490.1 2031190 R 487213 CDS YP_002743491.1 225861982 7685615 complement(2031651..2032094) 1 NC_012469.1 identified by match to protein family HMM PF03610; PTS system, IIA component 2032094 7685615 SPT_2177 Streptococcus pneumoniae Taiwan19F-14 PTS system, IIA component YP_002743491.1 2031651 R 487213 CDS YP_002743492.1 225861983 7686332 complement(2032075..2032515) 1 NC_012469.1 identified by match to protein family HMM PF05025; fucose operon FucU protein 2032515 7686332 SPT_2178 Streptococcus pneumoniae Taiwan19F-14 fucose operon FucU protein YP_002743492.1 2032075 R 487213 CDS YP_002743493.1 225861984 7686923 complement(2032527..2033165) 1 NC_012469.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 2033165 7686923 SPT_2179 Streptococcus pneumoniae Taiwan19F-14 L-fuculose phosphate aldolase YP_002743493.1 2032527 R 487213 CDS YP_002743494.1 225861985 7686668 complement(2033280..2034683) 1 NC_012469.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; rhamnulokinase (Rhamnulose kinase) 2034683 7686668 SPT_2180 Streptococcus pneumoniae Taiwan19F-14 rhamnulokinase (Rhamnulose kinase) YP_002743494.1 2033280 R 487213 CDS YP_002743495.1 225861986 7685990 2034859..2035632 1 NC_012469.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; regulator of fucose operon 2035632 7685990 SPT_2181 Streptococcus pneumoniae Taiwan19F-14 regulator of fucose operon YP_002743495.1 2034859 D 487213 CDS YP_002743496.1 225861987 7687033 complement(2036803..2038308) 1 NC_012469.1 identified by match to protein family HMM PF01297; match to protein family HMM PF09223; zinc-binding lipoprotein AdcA 2038308 7687033 SPT_2182 Streptococcus pneumoniae Taiwan19F-14 zinc-binding lipoprotein AdcA YP_002743496.1 2036803 R 487213 CDS YP_002743497.1 225861988 7686552 complement(2038318..2039124) 1 NC_012469.1 identified by match to protein family HMM PF00950; zinc ABC transporter permease 2039124 7686552 SPT_2183 Streptococcus pneumoniae Taiwan19F-14 zinc ABC transporter permease YP_002743497.1 2038318 R 487213 CDS YP_002743498.1 225861989 7686310 complement(2039117..2039821) 1 NC_012469.1 identified by match to protein family HMM PF00005; zinc transport system ATP-binding protein AdcC 2039821 7686310 SPT_2184 Streptococcus pneumoniae Taiwan19F-14 zinc transport system ATP-binding protein AdcC YP_002743498.1 2039117 R 487213 CDS YP_002743499.1 225861990 7685323 complement(2039821..2040261) 1 NC_012469.1 identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279; putative transcriptional repressor 2040261 7685323 SPT_2185 Streptococcus pneumoniae Taiwan19F-14 putative transcriptional repressor YP_002743499.1 2039821 R 487213 CDS YP_002743500.1 225861991 7686817 2040246..2040383 1 NC_012469.1 hypothetical protein 2040383 7686817 SPT_2186 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743500.1 2040246 D 487213 CDS YP_002743501.1 225861992 7687349 complement(2041677..2041916) 1 NC_012469.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 2041916 dltC 7687349 dltC Streptococcus pneumoniae Taiwan19F-14 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_002743501.1 2041677 R 487213 CDS YP_002743502.1 225861993 7686464 complement(2041930..2043174) 1 NC_012469.1 identified by match to protein family HMM PF03062; protein DltB 2043174 7686464 SPT_2190 Streptococcus pneumoniae Taiwan19F-14 protein DltB YP_002743502.1 2041930 R 487213 CDS YP_002743503.1 225861994 7685450 complement(2043171..2044721) 1 NC_012469.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 2044721 dltA 7685450 dltA Streptococcus pneumoniae Taiwan19F-14 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_002743503.1 2043171 R 487213 CDS YP_002743504.1 225861995 7685299 complement(2044742..2044873) 1 NC_012469.1 hypothetical protein 2044873 7685299 SPT_2192 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743504.1 2044742 R 487213 CDS YP_002743505.1 225861996 7685884 complement(2045187..2046365) 1 NC_012469.1 identified by match to protein family HMM PF07690; permease of the major facilitator superfamily 2046365 7685884 SPT_2193 Streptococcus pneumoniae Taiwan19F-14 permease of the major facilitator superfamily YP_002743505.1 2045187 R 487213 CDS YP_002743506.1 225861997 7687320 2049214..2049801 1 NC_012469.1 hypothetical protein 2049801 7687320 SPT_2196 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743506.1 2049214 D 487213 CDS YP_002743507.1 225861998 7687329 complement(2049888..2050091) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 2050091 7687329 SPT_2197 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743507.1 2049888 R 487213 CDS YP_002743508.1 225861999 7685931 2050193..2050309 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 2050309 7685931 SPT_2198 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743508.1 2050193 D 487213 CDS YP_002743509.1 225862000 7685351 complement(2050388..2051092) 1 NC_012469.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 2051092 7685351 SPT_2199 Streptococcus pneumoniae Taiwan19F-14 glycerol uptake facilitator protein YP_002743509.1 2050388 R 487213 CDS YP_002743510.1 225862001 7686126 complement(2051162..2052988) 1 NC_012469.1 identified by match to protein family HMM PF01266; alpha-glycerophosphate oxidase (Glycerol-3-phosphateoxidase) (Exported protein 6) 2052988 7686126 SPT_2200 Streptococcus pneumoniae Taiwan19F-14 alpha-glycerophosphate oxidase (Glycerol-3-phosphateoxidase) (Exported protein 6) YP_002743510.1 2051162 R 487213 CDS YP_002743511.1 225862002 7685401 complement(2053030..2054538) 1 NC_012469.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 2054538 glpK 7685401 glpK Streptococcus pneumoniae Taiwan19F-14 glycerol kinase YP_002743511.1 2053030 R 487213 CDS YP_002743512.1 225862003 7686636 complement(2054697..2056106) 1 NC_012469.1 identified by match to protein family HMM PF05043; M protein trans-acting positive regulator (MGA) 2056106 7686636 SPT_2202 Streptococcus pneumoniae Taiwan19F-14 M protein trans-acting positive regulator (MGA) YP_002743512.1 2054697 R 487213 CDS YP_002743513.1 225862004 7686360 2056289..2057161 1 NC_012469.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2057161 hslO 7686360 hslO Streptococcus pneumoniae Taiwan19F-14 Hsp33-like chaperonin YP_002743513.1 2056289 D 487213 CDS YP_002743514.1 225862005 7687025 2057148..2058128 1 NC_012469.1 identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 2058128 7687025 SPT_2204 Streptococcus pneumoniae Taiwan19F-14 tRNA-dihydrouridine synthase B YP_002743514.1 2057148 D 487213 CDS YP_002743515.1 225862006 7685476 complement(2061822..2063525) 1 NC_012469.1 identified by match to protein family HMM PF01473; surface protein PspC 2063525 7685476 SPT_2208 Streptococcus pneumoniae Taiwan19F-14 surface protein PspC YP_002743515.1 2061822 R 487213 CDS YP_002743516.1 225862007 7686997 complement(2063940..2064467) 1 NC_012469.1 identified by match to protein family HMM PF04140; hypothetical protein 2064467 7686997 SPT_2209 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743516.1 2063940 R 487213 CDS YP_002743517.1 225862008 7686354 complement(2064562..2065893) 1 NC_012469.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 2065893 7686354 SPT_2210 Streptococcus pneumoniae Taiwan19F-14 histidine kinase YP_002743517.1 2064562 R 487213 CDS YP_002743518.1 225862009 7687208 complement(2065890..2066543) 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2066543 7687208 SPT_2211 Streptococcus pneumoniae Taiwan19F-14 DNA-binding response regulator YP_002743518.1 2065890 R 487213 CDS YP_002743519.1 225862010 7685647 2066983..2067114 1 NC_012469.1 DNA alkylation repair enzyme 2067114 7685647 SPT_2212 Streptococcus pneumoniae Taiwan19F-14 DNA alkylation repair enzyme YP_002743519.1 2066983 D 487213 CDS YP_002743520.1 225862011 7685499 complement(2067185..2069617) 1 NC_012469.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; chaperone ClpB 1 2069617 7685499 SPT_2213 Streptococcus pneumoniae Taiwan19F-14 chaperone ClpB 1 YP_002743520.1 2067185 R 487213 CDS YP_002743521.1 225862012 7686767 complement(2069619..2070077) 1 NC_012469.1 identified by match to protein family HMM PF05848; transcriptional regulator CtsR 2070077 7686767 SPT_2214 Streptococcus pneumoniae Taiwan19F-14 transcriptional regulator CtsR YP_002743521.1 2069619 R 487213 CDS YP_002743522.1 225862013 7686443 complement(2070196..2070924) 1 NC_012469.1 identified by match to protein family HMM PF00005; anion ABC transporter ATP-binding protein 2070924 7686443 SPT_2215 Streptococcus pneumoniae Taiwan19F-14 anion ABC transporter ATP-binding protein YP_002743522.1 2070196 R 487213 CDS YP_002743523.1 225862014 7686411 complement(2070924..2071931) 1 NC_012469.1 identified by match to protein family HMM PF09084; ABC transporter substrate-binding protein 2071931 7686411 SPT_2216 Streptococcus pneumoniae Taiwan19F-14 ABC transporter substrate-binding protein YP_002743523.1 2070924 R 487213 CDS YP_002743524.1 225862015 7686627 complement(2071969..2072730) 1 NC_012469.1 identified by match to protein family HMM PF00528; ABC transporter permease 2072730 7686627 SPT_2217 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002743524.1 2071969 R 487213 CDS YP_002743525.1 225862016 7687278 complement(2072690..2072980) 1 NC_012469.1 hypothetical protein 2072980 7687278 SPT_2218 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743525.1 2072690 R 487213 CDS YP_002743526.1 225862017 7686492 complement(2073236..2074582) 1 NC_012469.1 identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460; choline binding protein D 2074582 7686492 SPT_2219 Streptococcus pneumoniae Taiwan19F-14 choline binding protein D YP_002743526.1 2073236 R 487213 CDS YP_002743527.1 225862018 7686020 complement(2074671..2074937) 1 NC_012469.1 identified by match to protein family HMM PF06257; hypothetical protein 2074937 7686020 SPT_2220 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743527.1 2074671 R 487213 CDS YP_002743528.1 225862019 7685962 complement(2074939..2076291) 1 NC_012469.1 unwinds double stranded DNA; replicative DNA helicase 2076291 dnaB 7685962 dnaB Streptococcus pneumoniae Taiwan19F-14 replicative DNA helicase YP_002743528.1 2074939 R 487213 CDS YP_002743529.1 225862020 7686311 complement(2076335..2076787) 1 NC_012469.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 2076787 rplI 7686311 rplI Streptococcus pneumoniae Taiwan19F-14 50S ribosomal protein L9 YP_002743529.1 2076335 R 487213 CDS YP_002743530.1 225862021 7687140 complement(2076784..2078757) 1 NC_012469.1 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein 2078757 7687140 SPT_2223 Streptococcus pneumoniae Taiwan19F-14 DHH subfamily 1 protein YP_002743530.1 2076784 R 487213 CDS YP_002743531.1 225862022 7685892 complement(2078893..2079441) 1 NC_012469.1 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosome-associated protein Y 2079441 7685892 SPT_2224 Streptococcus pneumoniae Taiwan19F-14 ribosome-associated protein Y YP_002743531.1 2078893 R 487213 CDS YP_002743532.1 225862023 7685212 complement(2079521..2080183) 1 NC_012469.1 putative competence protein ComF 2080183 7685212 SPT_2225 Streptococcus pneumoniae Taiwan19F-14 putative competence protein ComF YP_002743532.1 2079521 R 487213 CDS YP_002743533.1 225862024 7685378 complement(2080180..2081478) 1 NC_012469.1 identified by match to protein family HMM PF00271; match to protein family HMM PF04851; superfamily II ATP-dependent DNA/RNA helicase required for DNA uptake 2081478 7685378 SPT_2226 Streptococcus pneumoniae Taiwan19F-14 superfamily II ATP-dependent DNA/RNA helicase required for DNA uptake YP_002743533.1 2080180 R 487213 CDS YP_002743534.1 225862025 7685630 2081534..2082169 1 NC_012469.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 2082169 7685630 SPT_2227 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743534.1 2081534 D 487213 CDS YP_002743535.1 225862026 7685718 2082454..2083374 1 NC_012469.1 identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 2083374 cysK 7685718 cysK Streptococcus pneumoniae Taiwan19F-14 cysteine synthase A YP_002743535.1 2082454 D 487213 CDS YP_002743536.1 225862027 7685620 complement(2083571..2083840) 1 NC_012469.1 an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 2083840 7685620 SPT_2229 Streptococcus pneumoniae Taiwan19F-14 transposase YP_002743536.1 2083571 R 487213 CDS YP_002743537.1 225862028 7685390 2084002..2084268 1 NC_012469.1 transposase family protein 2084268 7685390 SPT_2230 Streptococcus pneumoniae Taiwan19F-14 transposase family protein YP_002743537.1 2084002 D 487213 CDS YP_002743538.1 225862029 7686067 complement(2084409..2084732) 1 NC_012469.1 identified by match to protein family HMM PF05717; IS66 family element, Orf2 2084732 7686067 SPT_2231 Streptococcus pneumoniae Taiwan19F-14 IS66 family element, Orf2 YP_002743538.1 2084409 R 487213 CDS YP_002743539.1 225862030 7685339 complement(2084978..2086018) 1 NC_012469.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 2086018 tsf 7685339 tsf Streptococcus pneumoniae Taiwan19F-14 elongation factor Ts YP_002743539.1 2084978 R 487213 CDS YP_002743540.1 225862031 7687236 complement(2086097..2086876) 1 NC_012469.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 2086876 rpsB 7687236 rpsB Streptococcus pneumoniae Taiwan19F-14 30S ribosomal protein S2 YP_002743540.1 2086097 R 487213 CDS YP_002743541.1 225862032 7686418 complement(2087100..2088278) 1 NC_012469.1 identified by match to protein family HMM PF05257; general stress protein GSP-781 2088278 7686418 SPT_2234 Streptococcus pneumoniae Taiwan19F-14 general stress protein GSP-781 YP_002743541.1 2087100 R 487213 CDS YP_002743542.1 225862033 7686638 complement(2088372..2088866) 1 NC_012469.1 identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426; rod shape-determining protein MreD 2088866 mreD 7686638 mreD Streptococcus pneumoniae Taiwan19F-14 rod shape-determining protein MreD YP_002743542.1 2088372 R 487213 CDS YP_002743543.1 225862034 7686330 complement(2088866..2089684) 1 NC_012469.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 2089684 mreC 7686330 mreC Streptococcus pneumoniae Taiwan19F-14 rod shape-determining protein MreC YP_002743543.1 2088866 R 487213 CDS YP_002743544.1 225862035 7685740 complement(2089743..2090537) 1 NC_012469.1 identified by match to protein family HMM PF02361; ABC transporter permease 2090537 7685740 SPT_2237 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002743544.1 2089743 R 487213 CDS YP_002743545.1 225862036 7686200 complement(2090530..2091369) 1 NC_012469.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2091369 cbiO 7686200 cbiO Streptococcus pneumoniae Taiwan19F-14 cobalt transporter ATP-binding subunit YP_002743545.1 2090530 R 487213 CDS YP_002743546.1 225862037 7685614 complement(2091354..2092181) 1 NC_012469.1 with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2092181 cbiO 7685614 cbiO Streptococcus pneumoniae Taiwan19F-14 cobalt transporter ATP-binding subunit YP_002743546.1 2091354 R 487213 CDS YP_002743547.1 225862038 7686727 complement(2092178..2092723) 1 NC_012469.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2092723 pgsA 7686727 pgsA Streptococcus pneumoniae Taiwan19F-14 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_002743547.1 2092178 R 487213 CDS YP_002743548.1 225862039 7686366 complement(2092734..2093555) 1 NC_012469.1 hypothetical protein 2093555 7686366 SPT_2241 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743548.1 2092734 R 487213 CDS YP_002743549.1 225862040 7685804 complement(2093597..2094880) 1 NC_012469.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family 2094880 7685804 SPT_2242 Streptococcus pneumoniae Taiwan19F-14 peptidase, M16 family YP_002743549.1 2093597 R 487213 CDS YP_002743550.1 225862041 7685840 complement(2094877..2096127) 1 NC_012469.1 identified by match to protein family HMM PF05193; peptidase, M16 family 2096127 7685840 SPT_2243 Streptococcus pneumoniae Taiwan19F-14 peptidase, M16 family YP_002743550.1 2094877 R 487213 CDS YP_002743551.1 225862042 7686754 2096286..2096654 1 NC_012469.1 identified by match to protein family HMM TIGR02988; S4 domain protein YaaA, putative 2096654 7686754 SPT_2244 Streptococcus pneumoniae Taiwan19F-14 S4 domain protein YaaA, putative YP_002743551.1 2096286 D 487213 CDS YP_002743552.1 225862043 7685525 2096657..2097754 1 NC_012469.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2097754 recF 7685525 recF Streptococcus pneumoniae Taiwan19F-14 recombination protein F YP_002743552.1 2096657 D 487213 CDS YP_002743553.1 225862044 7686963 complement(2097805..2099283) 1 NC_012469.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2099283 guaB 7686963 guaB Streptococcus pneumoniae Taiwan19F-14 inosine 5'-monophosphate dehydrogenase YP_002743553.1 2097805 R 487213 CDS YP_002743554.1 225862045 7686534 complement(2099435..2100460) 1 NC_012469.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II 2100460 trpS 7686534 trpS Streptococcus pneumoniae Taiwan19F-14 tryptophanyl-tRNA synthetase II YP_002743554.1 2099435 R 487213 CDS YP_002743555.1 225862046 7686885 2100666..2102288 1 NC_012469.1 identified by match to protein family HMM PF00005; ATPase component of ABC transporters with duplicated ATPase domains 2102288 7686885 SPT_2248 Streptococcus pneumoniae Taiwan19F-14 ATPase component of ABC transporters with duplicated ATPase domains YP_002743555.1 2100666 D 487213 CDS YP_002743556.1 225862047 7686523 2102350..2104902 1 NC_012469.1 ABC transporter permease 2104902 7686523 SPT_2249 Streptococcus pneumoniae Taiwan19F-14 ABC transporter permease YP_002743556.1 2102350 D 487213 CDS YP_002743557.1 225862048 7685814 complement(2105003..2105356) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 2105356 7685814 SPT_2250 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743557.1 2105003 R 487213 CDS YP_002743558.1 225862049 7685976 complement(2105353..2105850) 1 NC_012469.1 identified by glimmer; putative; hypothetical protein 2105850 7685976 SPT_2251 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743558.1 2105353 R 487213 CDS YP_002743559.1 225862050 7685967 2106186..2106728 1 NC_012469.1 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2106728 7685967 SPT_2252 Streptococcus pneumoniae Taiwan19F-14 TetR family transcriptional regulator YP_002743559.1 2106186 D 487213 CDS YP_002743560.1 225862051 7686579 complement(2106971..2107723) 1 NC_012469.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 2107723 7686579 SPT_2255 Streptococcus pneumoniae Taiwan19F-14 response regulator YP_002743560.1 2106971 R 487213 CDS YP_002743561.1 225862052 7685710 complement(2107720..2109045) 1 NC_012469.1 identified by match to protein family HMM PF02518; histidine protein kinase 2109045 7685710 SPT_2256 Streptococcus pneumoniae Taiwan19F-14 histidine protein kinase YP_002743561.1 2107720 R 487213 CDS YP_002743562.1 225862053 7686999 complement(2109066..2109191) 1 NC_012469.1 identified by match to protein family HMM PF03047; hypothetical protein 2109191 7686999 SPT_2257 Streptococcus pneumoniae Taiwan19F-14 hypothetical protein YP_002743562.1 2109066 R 487213 CDS YP_002743563.1 225862054 7685572 complement(2109473..2109952) 1 NC_012469.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2109952 7685572 SPT_2259 Streptococcus pneumoniae Taiwan19F-14 rRNA large subunit methyltransferase YP_002743563.1 2109473 R 487213 CDS YP_002743564.1 225862055 7685639 2110135..2111316 1 NC_012469.1 identified by match to protein family HMM PF00089; trypsin domain protein 2111316 7685639 SPT_2260 Streptococcus pneumoniae Taiwan19F-14 trypsin domain protein YP_002743564.1 2110135 D 487213 CDS YP_002743565.1 225862056 7686551 2111374..2112132 1 NC_012469.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; stage 0 sporulation protein J 2112132 7686551 SPT_2261 Streptococcus pneumoniae Taiwan19F-14 stage 0 sporulation protein J YP_002743565.1 2111374 D 487213 CDS