-- dump date 20140620_085319 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 487213000001 SEQ_END SEQ_END NC_012469.1 2112148 2112148 DR NC_012469.1; contig end 2112148..2112148 Streptococcus pneumoniae Taiwan19F-14 YP_002741522.1 CDS dnaA NC_012469.1 197 1558 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 197..1558 Streptococcus pneumoniae Taiwan19F-14 7686582 YP_002741523.1 CDS dnaN NC_012469.1 1717 2853 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1717..2853 Streptococcus pneumoniae Taiwan19F-14 7686368 YP_002741524.1 CDS SPT_0003 NC_012469.1 2918 3112 D identified by match to protein family HMM PF06107; hypothetical protein 2918..3112 Streptococcus pneumoniae Taiwan19F-14 7685742 YP_002741525.1 CDS SPT_0004 NC_012469.1 3563 3982 R phage protein complement(3563..3982) Streptococcus pneumoniae Taiwan19F-14 7687256 YP_002741526.1 CDS SPT_0005 NC_012469.1 4106 4297 D identified by glimmer; putative; hypothetical protein 4106..4297 Streptococcus pneumoniae Taiwan19F-14 7686281 YP_002741527.1 CDS SPT_0006 NC_012469.1 4601 4852 R identified by glimmer; putative; hypothetical protein complement(4601..4852) Streptococcus pneumoniae Taiwan19F-14 7687346 YP_002741528.1 CDS SPT_0007 NC_012469.1 4839 5180 R phage replication protein complement(4839..5180) Streptococcus pneumoniae Taiwan19F-14 7686026 YP_002741529.1 CDS SPT_0008 NC_012469.1 5231 5356 R identified by glimmer; putative; hypothetical protein complement(5231..5356) Streptococcus pneumoniae Taiwan19F-14 7686106 YP_002741530.1 CDS SPT_0009 NC_012469.1 5560 6084 R phage protein complement(5560..6084) Streptococcus pneumoniae Taiwan19F-14 7687142 YP_002741531.1 CDS SPT_0010 NC_012469.1 6177 6374 R identified by glimmer; putative; hypothetical protein complement(6177..6374) Streptococcus pneumoniae Taiwan19F-14 7686735 YP_002741532.1 CDS SPT_0011 NC_012469.1 6694 8259 R identified by match to protein family HMM PF08706; match to protein family HMM TIGR01613; DNA primase complement(6694..8259) Streptococcus pneumoniae Taiwan19F-14 7687305 YP_002741533.1 CDS SPT_0012 NC_012469.1 8228 9088 R identified by match to protein family HMM PF08708; phage protein complement(8228..9088) Streptococcus pneumoniae Taiwan19F-14 7686857 YP_002741534.1 CDS SPT_0013 NC_012469.1 9085 9357 R identified by similarity to GB:AAV62370.1; hypothetical protein complement(9085..9357) Streptococcus pneumoniae Taiwan19F-14 7686247 YP_002741535.1 CDS SPT_0014 NC_012469.1 9350 9691 R phage protein complement(9350..9691) Streptococcus pneumoniae Taiwan19F-14 7685649 YP_002741536.1 CDS SPT_0015 NC_012469.1 9672 9848 R identified by glimmer; putative; hypothetical protein complement(9672..9848) Streptococcus pneumoniae Taiwan19F-14 7686127 YP_002741537.1 CDS SPT_0016 NC_012469.1 9962 10177 R identified by glimmer; putative; hypothetical protein complement(9962..10177) Streptococcus pneumoniae Taiwan19F-14 7685964 YP_002741538.1 CDS SPT_0017 NC_012469.1 10170 10436 R hypothetical protein complement(10170..10436) Streptococcus pneumoniae Taiwan19F-14 7685811 YP_002741539.1 CDS SPT_0018 NC_012469.1 10454 10594 R hypothetical protein complement(10454..10594) Streptococcus pneumoniae Taiwan19F-14 7686404 YP_002741540.1 CDS SPT_0019 NC_012469.1 10606 11106 R identified by glimmer; putative; hypothetical protein complement(10606..11106) Streptococcus pneumoniae Taiwan19F-14 7685863 YP_002741541.1 CDS SPT_0020 NC_012469.1 11103 11243 R identified by glimmer; putative; hypothetical protein complement(11103..11243) Streptococcus pneumoniae Taiwan19F-14 7686712 YP_002741542.1 CDS SPT_0021 NC_012469.1 11644 11790 R identified by glimmer; putative; hypothetical protein complement(11644..11790) Streptococcus pneumoniae Taiwan19F-14 7687308 YP_002741543.1 CDS SPT_0022 NC_012469.1 11794 12222 R identified by glimmer; putative; hypothetical protein complement(11794..12222) Streptococcus pneumoniae Taiwan19F-14 7687368 YP_002741544.1 CDS SPT_0023 NC_012469.1 12376 12549 R hypothetical protein complement(12376..12549) Streptococcus pneumoniae Taiwan19F-14 7685799 YP_002741545.1 CDS SPT_0024 NC_012469.1 12788 13036 R identified by glimmer; putative; hypothetical protein complement(12788..13036) Streptococcus pneumoniae Taiwan19F-14 7687298 YP_002741546.1 CDS SPT_0025 NC_012469.1 13048 13653 R hypothetical protein complement(13048..13653) Streptococcus pneumoniae Taiwan19F-14 7686744 YP_002741547.1 CDS SPT_0026 NC_012469.1 13675 13983 R identified by glimmer; putative; hypothetical protein complement(13675..13983) Streptococcus pneumoniae Taiwan19F-14 7685243 YP_002741548.1 CDS SPT_0027 NC_012469.1 14245 15591 D identified by match to protein family HMM PF01609; Spn1 transposase 14245..15591 Streptococcus pneumoniae Taiwan19F-14 7687199 YP_002741549.1 CDS SPT_0028 NC_012469.1 15835 15987 R transcription regulator complement(15835..15987) Streptococcus pneumoniae Taiwan19F-14 7685269 YP_002741550.1 CDS SPT_0029 NC_012469.1 16230 16946 D identified by match to protein family HMM PF00717; match to protein family HMM PF01381; cI repressor 16230..16946 Streptococcus pneumoniae Taiwan19F-14 7685509 YP_002741551.1 CDS SPT_0030 NC_012469.1 16965 17633 D LIM domain protein 16965..17633 Streptococcus pneumoniae Taiwan19F-14 7686202 YP_002741552.1 CDS SPT_0031 NC_012469.1 17772 18440 D identified by match to protein family HMM PF02661; Fic protein family 17772..18440 Streptococcus pneumoniae Taiwan19F-14 7687146 YP_002741553.1 CDS SPT_0032 NC_012469.1 18904 19362 R identified by glimmer; putative; hypothetical protein complement(18904..19362) Streptococcus pneumoniae Taiwan19F-14 7686722 YP_002741554.1 CDS SPT_0033 NC_012469.1 19720 19842 D hypothetical protein 19720..19842 Streptococcus pneumoniae Taiwan19F-14 7685218 YP_002741555.1 CDS SPT_0034 NC_012469.1 20266 20502 D identified by similarity to GB:CAG39798.1; hypothetical protein 20266..20502 Streptococcus pneumoniae Taiwan19F-14 7687058 YP_002741556.1 CDS SPT_0035 NC_012469.1 20785 21090 D replication protein 20785..21090 Streptococcus pneumoniae Taiwan19F-14 7686452 YP_002741557.1 CDS SPT_0036 NC_012469.1 21195 21755 D putative DNA damage inducible protein 21195..21755 Streptococcus pneumoniae Taiwan19F-14 7686229 YP_002741558.1 CDS SPT_0037 NC_012469.1 22191 23357 D identified by match to protein family HMM PF00589; integrase 22191..23357 Streptococcus pneumoniae Taiwan19F-14 7686635 YP_002741559.1 CDS ychF NC_012469.1 23477 24592 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 23477..24592 Streptococcus pneumoniae Taiwan19F-14 7686449 YP_002741560.1 CDS pth NC_012469.1 24663 25232 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 24663..25232 Streptococcus pneumoniae Taiwan19F-14 7686018 YP_002741561.1 CDS mfd NC_012469.1 25233 28742 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 25233..28742 Streptococcus pneumoniae Taiwan19F-14 7686609 YP_002741562.1 CDS SPT_0041 NC_012469.1 28800 29066 D identified by match to protein family HMM PF01479; ribosome-associated heat shock protein implicated in the recycling of the 50S subunit 28800..29066 Streptococcus pneumoniae Taiwan19F-14 7687103 YP_002741563.1 CDS SPT_0042 NC_012469.1 29059 29427 D identified by match to protein family HMM PF04977; septum formation initiator 29059..29427 Streptococcus pneumoniae Taiwan19F-14 7686137 YP_002741564.1 CDS SPT_0043 NC_012469.1 29432 29554 D hypothetical protein 29432..29554 Streptococcus pneumoniae Taiwan19F-14 7685652 YP_002741565.1 CDS SPT_0044 NC_012469.1 29547 30815 D beta-lactamase class A 29547..30815 Streptococcus pneumoniae Taiwan19F-14 7687007 YP_002741566.1 CDS SPT_0045 NC_012469.1 30812 32089 D identified by match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433; tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) 30812..32089 Streptococcus pneumoniae Taiwan19F-14 7687387 YP_002741567.1 CDS hpt NC_012469.1 32093 32635 D identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 32093..32635 Streptococcus pneumoniae Taiwan19F-14 7685907 YP_002741568.1 CDS SPT_0047 NC_012469.1 32651 34609 D identified by match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; putative Cell division protease FtsH homolog 32651..34609 Streptococcus pneumoniae Taiwan19F-14 7687010 YP_002741569.1 CDS SPT_0048 NC_012469.1 34731 35210 D competence-specific global transcription modulator 34731..35210 Streptococcus pneumoniae Taiwan19F-14 7686461 YP_002741570.1 CDS SPT_0058 NC_012469.1 42067 42303 D hypothetical protein 42067..42303 Streptococcus pneumoniae Taiwan19F-14 7687118 YP_002741571.1 CDS purA NC_012469.1 42492 43820 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 42492..43820 Streptococcus pneumoniae Taiwan19F-14 7685482 YP_002741572.1 CDS SPT_0060 NC_012469.1 44021 44488 D identified by match to protein family HMM PF00383; tRNA-specific adenosine deaminase 44021..44488 Streptococcus pneumoniae Taiwan19F-14 7685516 YP_002741573.1 CDS dut NC_012469.1 44675 45118 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 44675..45118 Streptococcus pneumoniae Taiwan19F-14 7685543 YP_002741574.1 CDS SPT_0062 NC_012469.1 45078 45635 D identified by match to protein family HMM PF00300; phosphoglycerate mutase family protein 45078..45635 Streptococcus pneumoniae Taiwan19F-14 7686375 YP_002741575.1 CDS radA NC_012469.1 45748 47010 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 45748..47010 Streptococcus pneumoniae Taiwan19F-14 7686982 YP_002741576.1 CDS SPT_0064 NC_012469.1 47083 47580 D identified by match to protein family HMM PF00484; carbonate dehydratase 47083..47580 Streptococcus pneumoniae Taiwan19F-14 7685506 YP_002741577.1 CDS SPT_0065 NC_012469.1 47605 48420 D hypothetical protein 47605..48420 Streptococcus pneumoniae Taiwan19F-14 7686314 YP_002741578.1 CDS SPT_0066 NC_012469.1 48565 49533 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 48565..49533 Streptococcus pneumoniae Taiwan19F-14 7687035 YP_002741579.1 CDS SPT_0067 NC_012469.1 50077 50310 R hypothetical protein complement(50077..50310) Streptococcus pneumoniae Taiwan19F-14 7686214 YP_002741580.1 CDS SPT_0068 NC_012469.1 50268 50594 R identified by glimmer; putative; hypothetical protein complement(50268..50594) Streptococcus pneumoniae Taiwan19F-14 7686932 YP_002741581.1 CDS SPT_0069 NC_012469.1 50634 50948 R hypothetical protein complement(50634..50948) Streptococcus pneumoniae Taiwan19F-14 7686640 YP_002741582.1 CDS SPT_0070 NC_012469.1 51240 53873 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 51240..53873 Streptococcus pneumoniae Taiwan19F-14 7687123 YP_002741583.1 CDS SPT_0071 NC_012469.1 53958 54395 D identified by match to protein family HMM PF02629; CoA binding protein 53958..54395 Streptococcus pneumoniae Taiwan19F-14 7685535 YP_002741584.1 CDS SPT_0072 NC_012469.1 54578 55588 R identified by match to protein family HMM PF03601; hypothetical protein complement(54578..55588) Streptococcus pneumoniae Taiwan19F-14 7686024 YP_002741585.1 CDS SPT_0073 NC_012469.1 55737 56906 D catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 55737..56906 Streptococcus pneumoniae Taiwan19F-14 7686532 YP_002741586.1 CDS recO NC_012469.1 56903 57673 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 56903..57673 Streptococcus pneumoniae Taiwan19F-14 7685958 YP_002741587.1 CDS plsX NC_012469.1 57670 58662 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 57670..58662 Streptococcus pneumoniae Taiwan19F-14 7685340 YP_002741588.1 CDS SPT_0076 NC_012469.1 58668 58901 D hypothetical protein 58668..58901 Streptococcus pneumoniae Taiwan19F-14 7687227 YP_002741589.1 CDS SPT_0077 NC_012469.1 58944 59237 D mobile genetic element 58944..59237 Streptococcus pneumoniae Taiwan19F-14 7685436 YP_002741590.1 CDS SPT_0078 NC_012469.1 59440 59670 D identified by match to protein family HMM TIGR01847; hypothetical protein 59440..59670 Streptococcus pneumoniae Taiwan19F-14 7685407 YP_002741591.1 CDS SPT_0079 NC_012469.1 59673 59798 D identified by glimmer; putative; hypothetical protein 59673..59798 Streptococcus pneumoniae Taiwan19F-14 7687245 YP_002741592.1 CDS SPT_0080 NC_012469.1 60385 62538 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM PF03412; match to protein family HMM TIGR01193; transport/processing ATP-binding protein ComA 60385..62538 Streptococcus pneumoniae Taiwan19F-14 7687293 YP_002741593.1 CDS SPT_0081 NC_012469.1 62551 63900 D identified by match to protein family HMM TIGR01000; transport protein ComB 62551..63900 Streptococcus pneumoniae Taiwan19F-14 7686484 YP_002741594.1 CDS purC NC_012469.1 64070 64777 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 64070..64777 Streptococcus pneumoniae Taiwan19F-14 7685246 YP_002741595.1 CDS SPT_0083 NC_012469.1 64788 64922 D phosphoribosylaminoimidazole-succinocarboxamide synthase (saicar synthetase) 64788..64922 Streptococcus pneumoniae Taiwan19F-14 7686710 YP_002741596.1 CDS SPT_0084 NC_012469.1 64979 68704 D identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857; phosphoribosylformylglycinamidine synthase 64979..68704 Streptococcus pneumoniae Taiwan19F-14 7686001 YP_002741597.1 CDS purF NC_012469.1 68797 70239 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 68797..70239 Streptococcus pneumoniae Taiwan19F-14 7686585 YP_002741598.1 CDS purM NC_012469.1 70276 71298 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 70276..71298 Streptococcus pneumoniae Taiwan19F-14 7685670 YP_002741599.1 CDS purN NC_012469.1 71295 71840 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 71295..71840 Streptococcus pneumoniae Taiwan19F-14 7686775 YP_002741600.1 CDS SPT_0088 NC_012469.1 71924 72433 D identified by match to protein family HMM PF04892; teicoplanin resistance protein 71924..72433 Streptococcus pneumoniae Taiwan19F-14 7685852 YP_002741601.1 CDS purH NC_012469.1 72458 74005 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 72458..74005 Streptococcus pneumoniae Taiwan19F-14 7687172 YP_002741602.1 CDS purD NC_012469.1 74127 75389 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 74127..75389 Streptococcus pneumoniae Taiwan19F-14 7686186 YP_002741603.1 CDS purE NC_012469.1 75792 76280 D identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 75792..76280 Streptococcus pneumoniae Taiwan19F-14 7685489 YP_002741604.1 CDS purK NC_012469.1 76267 77358 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 76267..77358 Streptococcus pneumoniae Taiwan19F-14 7686297 YP_002741605.1 CDS SPT_0093 NC_012469.1 77368 77595 D hypothetical protein 77368..77595 Streptococcus pneumoniae Taiwan19F-14 7685889 YP_002741606.1 CDS purB NC_012469.1 77658 78956 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 77658..78956 Streptococcus pneumoniae Taiwan19F-14 7685878 YP_002741607.1 CDS SPT_0095 NC_012469.1 79011 82949 R identified by match to protein family HMM PF00728; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-N-acetylhexosaminidase complement(79011..82949) Streptococcus pneumoniae Taiwan19F-14 7686763 YP_002741608.1 CDS SPT_0096 NC_012469.1 83265 84008 R identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator complement(83265..84008) Streptococcus pneumoniae Taiwan19F-14 7686832 YP_002741609.1 CDS SPT_0097 NC_012469.1 84329 86116 D identified by match to protein family HMM PF01301; match to protein family HMM PF02449; beta-galactosidase (Lactase) 84329..86116 Streptococcus pneumoniae Taiwan19F-14 7685731 YP_002741610.1 CDS SPT_0098 NC_012469.1 86113 86589 D identified by match to protein family HMM PF03830; phosphotransferase system sugar-specific eiib component 86113..86589 Streptococcus pneumoniae Taiwan19F-14 7685415 YP_002741611.1 CDS SPT_0099 NC_012469.1 86617 87522 D identified by match to protein family HMM PF03609; PTS system, IIC component 86617..87522 Streptococcus pneumoniae Taiwan19F-14 7686413 YP_002741612.1 CDS SPT_0100 NC_012469.1 87509 88324 D identified by match to protein family HMM PF03613; PTS system, IID component 87509..88324 Streptococcus pneumoniae Taiwan19F-14 7685697 YP_002741613.1 CDS SPT_0101 NC_012469.1 88331 88735 D identified by match to protein family HMM PF03610; phosphotransferase system sugar-specific EII component 88331..88735 Streptococcus pneumoniae Taiwan19F-14 7686509 YP_002741614.1 CDS SPT_0102 NC_012469.1 89029 90195 D identified by match to protein family HMM PF01380; putative tagatose-6-phosphate ketose/aldose isomerase 89029..90195 Streptococcus pneumoniae Taiwan19F-14 7686294 YP_002741615.1 CDS SPT_0103 NC_012469.1 90311 91348 D identified by match to protein family HMM PF01263; aldose 1-epimerase 90311..91348 Streptococcus pneumoniae Taiwan19F-14 7685477 YP_002741616.1 CDS SPT_0104 NC_012469.1 91555 92409 D identified by match to protein family HMM PF00903; glyoxalase family protein 91555..92409 Streptococcus pneumoniae Taiwan19F-14 7686114 YP_002741617.1 CDS SPT_0105 NC_012469.1 92559 92816 D identified by match to protein family HMM PF02583; hypothetical protein 92559..92816 Streptococcus pneumoniae Taiwan19F-14 7686249 YP_002741618.1 CDS SPT_0106 NC_012469.1 92858 93220 R chlorohydrolase complement(92858..93220) Streptococcus pneumoniae Taiwan19F-14 7685532 YP_002741619.1 CDS SPT_0107 NC_012469.1 93274 93570 R identified by match to protein family HMM PF00581; hypothetical protein complement(93274..93570) Streptococcus pneumoniae Taiwan19F-14 7686038 YP_002741620.1 CDS SPT_0108 NC_012469.1 93560 93679 R coenzyme A disulfide reductase complement(93560..93679) Streptococcus pneumoniae Taiwan19F-14 7687379 YP_002741621.1 CDS SPT_0109 NC_012469.1 93791 94555 D identified by match to protein family HMM PF01048; phosphorylase, Pnp/Udp family 93791..94555 Streptococcus pneumoniae Taiwan19F-14 7686468 YP_002741622.1 CDS SPT_0110 NC_012469.1 94795 94947 R identified by glimmer; putative; hypothetical protein complement(94795..94947) Streptococcus pneumoniae Taiwan19F-14 7685687 YP_002741623.1 CDS SPT_0111 NC_012469.1 95165 96544 D identified by match to protein family HMM PF02386; Trk transporter membrane-spanning protein - K+ transport 95165..96544 Streptococcus pneumoniae Taiwan19F-14 7686826 YP_002741624.1 CDS SPT_0112 NC_012469.1 96558 97223 D identified by match to protein family HMM PF02254; potassium uptake protein, Trk family 96558..97223 Streptococcus pneumoniae Taiwan19F-14 7686003 YP_002741625.1 CDS SPT_0113 NC_012469.1 97358 97516 D identified by glimmer; putative; hypothetical protein 97358..97516 Streptococcus pneumoniae Taiwan19F-14 7686602 YP_002741626.1 CDS SPT_0116 NC_012469.1 98710 101739 D identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 98710..101739 Streptococcus pneumoniae Taiwan19F-14 7685211 YP_002741627.1 CDS SPT_0117 NC_012469.1 101906 102604 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator SaeR 101906..102604 Streptococcus pneumoniae Taiwan19F-14 7686566 YP_002741628.1 CDS SPT_0118 NC_012469.1 102601 103653 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase 102601..103653 Streptococcus pneumoniae Taiwan19F-14 7685748 YP_002741629.1 CDS rpsD NC_012469.1 103848 104459 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 103848..104459 Streptococcus pneumoniae Taiwan19F-14 7685951 YP_002741630.1 CDS SPT_0120 NC_012469.1 105225 105485 D hypothetical protein 105225..105485 Streptococcus pneumoniae Taiwan19F-14 7685770 YP_002741631.1 CDS SPT_0121 NC_012469.1 105439 105660 D hypothetical protein 105439..105660 Streptococcus pneumoniae Taiwan19F-14 7687207 YP_002741632.1 CDS SPT_0122 NC_012469.1 105949 106908 D identified by match to protein family HMM PF00528; sugar ABC transporter permease 105949..106908 Streptococcus pneumoniae Taiwan19F-14 7686279 YP_002741633.1 CDS SPT_0123 NC_012469.1 106922 107845 D identified by match to protein family HMM PF00528; protein LplC 106922..107845 Streptococcus pneumoniae Taiwan19F-14 7685911 YP_002741634.1 CDS SPT_0124 NC_012469.1 108103 109578 D identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein 108103..109578 Streptococcus pneumoniae Taiwan19F-14 7687280 YP_002741635.1 CDS SPT_0125 NC_012469.1 109850 110836 D identified by match to protein family HMM PF00581; hypothetical protein 109850..110836 Streptococcus pneumoniae Taiwan19F-14 7686267 YP_002741636.1 CDS SPT_0126 NC_012469.1 111111 111971 D hypothetical protein 111111..111971 Streptococcus pneumoniae Taiwan19F-14 7687340 YP_002741637.1 CDS SPT_0127 NC_012469.1 112358 112522 D identified by glimmer; putative; hypothetical protein 112358..112522 Streptococcus pneumoniae Taiwan19F-14 7685669 YP_002741638.1 CDS SPT_0128 NC_012469.1 113248 114594 D identified by match to protein family HMM PF01609; Spn1 transposase 113248..114594 Streptococcus pneumoniae Taiwan19F-14 7686798 YP_002741639.1 CDS SPT_0129 NC_012469.1 115516 115641 D identified by glimmer; putative; hypothetical protein 115516..115641 Streptococcus pneumoniae Taiwan19F-14 7687094 YP_002741640.1 CDS SPT_0130 NC_012469.1 115666 115863 D macrolide export ATP-binding/permease protein MacB 115666..115863 Streptococcus pneumoniae Taiwan19F-14 7686481 YP_002741641.1 CDS SPT_0131 NC_012469.1 116100 117164 R hypothetical protein complement(116100..117164) Streptococcus pneumoniae Taiwan19F-14 7686780 YP_002741642.1 CDS SPT_0132 NC_012469.1 117227 118138 R hypothetical protein complement(117227..118138) Streptococcus pneumoniae Taiwan19F-14 7686035 YP_002741643.1 CDS SPT_0133 NC_012469.1 118131 118724 R hypothetical protein complement(118131..118724) Streptococcus pneumoniae Taiwan19F-14 7685205 YP_002741644.1 CDS SPT_0134 NC_012469.1 118711 119037 R identified by match to protein family HMM PF03551; transcriptional regulator, PadR family complement(118711..119037) Streptococcus pneumoniae Taiwan19F-14 7687049 YP_002741645.1 CDS SPT_0135 NC_012469.1 119176 120342 R identified by match to protein family HMM PF07690; cyanate permease complement(119176..120342) Streptococcus pneumoniae Taiwan19F-14 7687270 YP_002741646.1 CDS SPT_0136 NC_012469.1 120493 121557 D identified by match to protein family HMM PF00535; glycosyl transferase 120493..121557 Streptococcus pneumoniae Taiwan19F-14 7686691 YP_002741647.1 CDS SPT_0137 NC_012469.1 121599 123449 D identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; CapD protein, required for the biosynthesis of type 1 capsular polysaccharide 121599..123449 Streptococcus pneumoniae Taiwan19F-14 7685864 YP_002741648.1 CDS SPT_0138 NC_012469.1 123799 124431 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphoglycolate phosphatase complement(123799..124431) Streptococcus pneumoniae Taiwan19F-14 7686633 YP_002741649.1 CDS sdaAA NC_012469.1 124453 125325 R identified by match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase, iron-sulfur-dependent, alpha subunit complement(124453..125325) Streptococcus pneumoniae Taiwan19F-14 7685203 YP_002741650.1 CDS sdaAB NC_012469.1 125334 126005 R identified by match to protein family HMM PF01842; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase, iron-sulfur-dependent, beta subunit complement(125334..126005) Streptococcus pneumoniae Taiwan19F-14 7686118 YP_002741651.1 CDS SPT_0141 NC_012469.1 126247 126834 D identified by match to protein family HMM PF01476; LysM domain protein 126247..126834 Streptococcus pneumoniae Taiwan19F-14 7686193 YP_002741652.1 CDS SPT_0142 NC_012469.1 126886 127206 R hypothetical protein complement(126886..127206) Streptococcus pneumoniae Taiwan19F-14 7686860 YP_002741653.1 CDS SPT_0143 NC_012469.1 127658 127906 D identified by match to protein family HMM TIGR01653; bacteriocin, lactococcin 972 family 127658..127906 Streptococcus pneumoniae Taiwan19F-14 7686852 YP_002741654.1 CDS SPT_0144 NC_012469.1 127961 130069 D identified by match to protein family HMM TIGR01654; amino acid ABC transporter permease 127961..130069 Streptococcus pneumoniae Taiwan19F-14 7686039 YP_002741655.1 CDS SPT_0145 NC_012469.1 130066 130707 D identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB 130066..130707 Streptococcus pneumoniae Taiwan19F-14 7686946 YP_002741656.1 CDS SPT_0146 NC_012469.1 130914 131720 D identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 130914..131720 Streptococcus pneumoniae Taiwan19F-14 7686573 YP_002741657.1 CDS SPT_0147 NC_012469.1 131737 132156 D identified by match to protein family HMM PF00764; argininosuccinate synthase (Citrulline--aspartateligase) 131737..132156 Streptococcus pneumoniae Taiwan19F-14 7687194 YP_002741658.1 CDS SPT_0148 NC_012469.1 132446 132766 R hypothetical protein complement(132446..132766) Streptococcus pneumoniae Taiwan19F-14 7686275 YP_002741659.1 CDS SPT_0149 NC_012469.1 133525 133893 D hypothetical protein 133525..133893 Streptococcus pneumoniae Taiwan19F-14 7685713 YP_002741660.1 CDS SPT_0150 NC_012469.1 134293 135156 R identified by match to protein family HMM PF01381; helix-turn-helix domain protein complement(134293..135156) Streptococcus pneumoniae Taiwan19F-14 7685842 YP_002741661.1 CDS SPT_0151 NC_012469.1 135724 135960 D hypothetical protein 135724..135960 Streptococcus pneumoniae Taiwan19F-14 7686765 YP_002741662.1 CDS SPT_0152 NC_012469.1 136258 136434 D hypothetical protein 136258..136434 Streptococcus pneumoniae Taiwan19F-14 7685880 YP_002741663.1 CDS SPT_0153 NC_012469.1 136588 136800 D hypothetical protein 136588..136800 Streptococcus pneumoniae Taiwan19F-14 7686648 YP_002741664.1 CDS SPT_0154 NC_012469.1 137216 137578 D hypothetical protein 137216..137578 Streptococcus pneumoniae Taiwan19F-14 7685798 YP_002741665.1 CDS SPT_0155 NC_012469.1 137961 139019 D hypothetical protein 137961..139019 Streptococcus pneumoniae Taiwan19F-14 7685665 YP_002741666.1 CDS SPT_0156 NC_012469.1 139335 140312 D hypothetical protein 139335..140312 Streptococcus pneumoniae Taiwan19F-14 7685313 YP_002741667.1 CDS SPT_0157 NC_012469.1 140689 141063 D hypothetical protein 140689..141063 Streptococcus pneumoniae Taiwan19F-14 7687398 YP_002741668.1 CDS SPT_0158 NC_012469.1 141070 141252 D hypothetical protein 141070..141252 Streptococcus pneumoniae Taiwan19F-14 7685376 YP_002741669.1 CDS SPT_0159 NC_012469.1 141271 142173 D hypothetical protein 141271..142173 Streptococcus pneumoniae Taiwan19F-14 7686486 YP_002741670.1 CDS SPT_0160 NC_012469.1 142229 142582 D hypothetical protein 142229..142582 Streptococcus pneumoniae Taiwan19F-14 7686964 YP_002741671.1 CDS SPT_0161 NC_012469.1 142579 143307 D hypothetical protein 142579..143307 Streptococcus pneumoniae Taiwan19F-14 7686340 YP_002741672.1 CDS SPT_0162 NC_012469.1 144442 144681 D hypothetical protein 144442..144681 Streptococcus pneumoniae Taiwan19F-14 7686747 YP_002741673.1 CDS SPT_0163 NC_012469.1 145231 147405 D identified by match to protein family HMM PF01473; pneumococcal surface protein A 145231..147405 Streptococcus pneumoniae Taiwan19F-14 7687400 YP_002741674.1 CDS SPT_0164 NC_012469.1 147658 147783 D identified by glimmer; putative; hypothetical protein 147658..147783 Streptococcus pneumoniae Taiwan19F-14 7686972 YP_002741675.1 CDS mnmA NC_012469.1 147806 148927 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 147806..148927 Streptococcus pneumoniae Taiwan19F-14 7686674 YP_002741676.1 CDS SPT_0166 NC_012469.1 149068 149523 D identified by match to protein family HMM PF00293; MutT/nudix family protein 149068..149523 Streptococcus pneumoniae Taiwan19F-14 7686169 YP_002741677.1 CDS gidA NC_012469.1 149533 151446 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 149533..151446 Streptococcus pneumoniae Taiwan19F-14 7686637 YP_002741678.1 CDS SPT_0168 NC_012469.1 151578 151727 R chlorohydrolase complement(151578..151727) Streptococcus pneumoniae Taiwan19F-14 7686232 YP_002741679.1 CDS SPT_0169 NC_012469.1 151799 153478 R identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; metallo-beta-lactamase superfamily protein domain protein complement(151799..153478) Streptococcus pneumoniae Taiwan19F-14 7686082 YP_002741680.1 CDS SPT_0170 NC_012469.1 153480 153713 R identified by match to protein family HMM PF07288; hypothetical protein complement(153480..153713) Streptococcus pneumoniae Taiwan19F-14 7685658 YP_002741681.1 CDS SPT_0171 NC_012469.1 154039 154284 R identified by glimmer; putative; hypothetical protein complement(154039..154284) Streptococcus pneumoniae Taiwan19F-14 7687001 YP_002741682.1 CDS SPT_0172 NC_012469.1 154531 154683 R identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein complement(154531..154683) Streptococcus pneumoniae Taiwan19F-14 7686617 YP_002741683.1 CDS SPT_0173 NC_012469.1 154685 154870 R hypothetical protein complement(154685..154870) Streptococcus pneumoniae Taiwan19F-14 7686259 YP_002741684.1 CDS SPT_0174 NC_012469.1 155048 155731 D identified by match to protein family HMM PF00814; glycoprotein endopeptidase 155048..155731 Streptococcus pneumoniae Taiwan19F-14 7686125 YP_002741685.1 CDS rimI NC_012469.1 155728 156165 D identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 155728..156165 Streptococcus pneumoniae Taiwan19F-14 7686316 YP_002741686.1 CDS SPT_0176 NC_012469.1 156155 157165 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 156155..157165 Streptococcus pneumoniae Taiwan19F-14 7686986 YP_002741687.1 CDS SPT_0181 NC_012469.1 160948 161823 D identified by match to protein family HMM PF00535; glycosyl transferase, family 2 160948..161823 Streptococcus pneumoniae Taiwan19F-14 7687209 YP_002741688.1 CDS SPT_0182 NC_012469.1 161910 163526 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 161910..163526 Streptococcus pneumoniae Taiwan19F-14 7685463 YP_002741689.1 CDS SPT_0183 NC_012469.1 163546 163701 D identified by glimmer; putative; hypothetical protein 163546..163701 Streptococcus pneumoniae Taiwan19F-14 7686463 YP_002741690.1 CDS SPT_0184 NC_012469.1 164078 164302 D hypothetical protein 164078..164302 Streptococcus pneumoniae Taiwan19F-14 7687020 YP_002741691.1 CDS SPT_0185 NC_012469.1 164853 165053 D hypothetical protein 164853..165053 Streptococcus pneumoniae Taiwan19F-14 7687391 YP_002741692.1 CDS SPT_0188 NC_012469.1 166632 167495 D identified by match to protein family HMM TIGR01716; MutR 166632..167495 Streptococcus pneumoniae Taiwan19F-14 7686331 YP_002741693.1 CDS SPT_0189 NC_012469.1 167786 167983 D identified by glimmer; putative; hypothetical protein 167786..167983 Streptococcus pneumoniae Taiwan19F-14 7687165 YP_002741694.1 CDS SPT_0190 NC_012469.1 168051 168716 D identified by match to protein family HMM PF02517; caax amino protease family 168051..168716 Streptococcus pneumoniae Taiwan19F-14 7686292 YP_002741695.1 CDS SPT_0191 NC_012469.1 168788 170014 D identified by match to protein family HMM PF07690; transporter, major facilitator family protein 168788..170014 Streptococcus pneumoniae Taiwan19F-14 7687393 YP_002741696.1 CDS SPT_0192 NC_012469.1 170290 170487 R identified by glimmer; putative; hypothetical protein complement(170290..170487) Streptococcus pneumoniae Taiwan19F-14 7686248 YP_002741697.1 CDS SPT_0193 NC_012469.1 170558 171214 D identified by match to protein family HMM PF03591; branched-chain amino acid permease 170558..171214 Streptococcus pneumoniae Taiwan19F-14 7685894 YP_002741698.1 CDS SPT_0194 NC_012469.1 171204 171527 D identified by match to protein family HMM PF05437; branched-chain amino acid transport protein AzlD 171204..171527 Streptococcus pneumoniae Taiwan19F-14 7686816 YP_002741699.1 CDS SPT_0195 NC_012469.1 171631 172461 D identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 171631..172461 Streptococcus pneumoniae Taiwan19F-14 7685834 YP_002741700.1 CDS SPT_0196 NC_012469.1 172615 173469 D identified by match to protein family HMM PF03180; lipoprotein 172615..173469 Streptococcus pneumoniae Taiwan19F-14 7686524 YP_002741701.1 CDS SPT_0197 NC_012469.1 173569 174942 D identified by match to protein family HMM PF01546; match to protein family HMM PF07687; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase 173569..174942 Streptococcus pneumoniae Taiwan19F-14 7685704 YP_002741702.1 CDS SPT_0198 NC_012469.1 174935 175996 D identified by match to protein family HMM PF00005; methionine import ATP-binding protein MetN 174935..175996 Streptococcus pneumoniae Taiwan19F-14 7687262 YP_002741703.1 CDS SPT_0199 NC_012469.1 175998 176690 D identified by match to protein family HMM PF00528; ABC transporter permease 175998..176690 Streptococcus pneumoniae Taiwan19F-14 7685542 YP_002741704.1 CDS SPT_0200 NC_012469.1 176720 177289 R identified by match to protein family HMM TIGR02185; membrane-bound protein complement(176720..177289) Streptococcus pneumoniae Taiwan19F-14 7686339 YP_002741705.1 CDS SPT_0201 NC_012469.1 177424 178038 D identified by match to protein family HMM PF04854; hypothetical protein 177424..178038 Streptococcus pneumoniae Taiwan19F-14 7685773 YP_002741706.1 CDS SPT_0202 NC_012469.1 178088 179686 D identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF06580; sensor histidine kinase, putative 178088..179686 Streptococcus pneumoniae Taiwan19F-14 7686235 YP_002741707.1 CDS SPT_0203 NC_012469.1 179698 180984 D identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 179698..180984 Streptococcus pneumoniae Taiwan19F-14 7686675 YP_002741708.1 CDS SPT_0204 NC_012469.1 181036 181569 D hypothetical protein 181036..181569 Streptococcus pneumoniae Taiwan19F-14 7686659 YP_002741709.1 CDS SPT_0205 NC_012469.1 181647 182117 D has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 181647..182117 Streptococcus pneumoniae Taiwan19F-14 7687243 YP_002741710.1 CDS SPT_0206 NC_012469.1 182423 183769 R identified by match to protein family HMM PF01609; Spn1 transposase complement(182423..183769) Streptococcus pneumoniae Taiwan19F-14 7686155 YP_002741711.1 CDS SPT_0207 NC_012469.1 184118 185380 R mn2+ and fe2+ transporter of the nramp family complement(184118..185380) Streptococcus pneumoniae Taiwan19F-14 7686399 YP_002741712.1 CDS SPT_0208 NC_012469.1 185690 186148 R hypothetical protein complement(185690..186148) Streptococcus pneumoniae Taiwan19F-14 7685446 YP_002741713.1 CDS SPT_0209 NC_012469.1 186145 186585 R identified by match to protein family HMM PF04397; response regulator of the LytR/AlgR family complement(186145..186585) Streptococcus pneumoniae Taiwan19F-14 7686757 YP_002741714.1 CDS SPT_0210 NC_012469.1 186673 186798 R identified by glimmer; putative; hypothetical protein complement(186673..186798) Streptococcus pneumoniae Taiwan19F-14 7686148 YP_002741715.1 CDS mutL NC_012469.1 186941 188890 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 186941..188890 Streptococcus pneumoniae Taiwan19F-14 7687029 YP_002741716.1 CDS ribH NC_012469.1 189215 189682 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(189215..189682) Streptococcus pneumoniae Taiwan19F-14 7686005 YP_002741717.1 CDS SPT_0213 NC_012469.1 189683 190888 R identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; riboflavin biosynthesis protein ribAB complement(189683..190888) Streptococcus pneumoniae Taiwan19F-14 7686924 YP_002741718.1 CDS ribE NC_012469.1 190908 191543 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(190908..191543) Streptococcus pneumoniae Taiwan19F-14 7685646 YP_002741719.1 CDS ribD NC_012469.1 191528 192628 R identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00227; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD complement(191528..192628) Streptococcus pneumoniae Taiwan19F-14 7687181 YP_002741720.1 CDS ruvA NC_012469.1 193033 193626 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 193033..193626 Streptococcus pneumoniae Taiwan19F-14 7685296 YP_002741721.1 CDS SPT_0217 NC_012469.1 193636 194199 D identified by match to protein family HMM PF03352; DNA-3-methyladenine glycosylase 1 193636..194199 Streptococcus pneumoniae Taiwan19F-14 7685466 YP_002741722.1 CDS SPT_0218 NC_012469.1 194196 194873 D identified by match to protein family HMM PF02517; caax amino protease family 194196..194873 Streptococcus pneumoniae Taiwan19F-14 7687030 YP_002741723.1 CDS SPT_0219 NC_012469.1 195010 196041 R identified by match to protein family HMM PF02016; MccC family protein complement(195010..196041) Streptococcus pneumoniae Taiwan19F-14 7686014 YP_002741724.1 CDS SPT_0220 NC_012469.1 196296 196979 R identified by match to protein family HMM PF06570; hypothetical protein complement(196296..196979) Streptococcus pneumoniae Taiwan19F-14 7687215 YP_002741725.1 CDS SPT_0221 NC_012469.1 196991 197935 R identified by match to protein family HMM PF01544; magnesium and cobalt transporter complement(196991..197935) Streptococcus pneumoniae Taiwan19F-14 7686682 YP_002741726.1 CDS SPT_0222 NC_012469.1 198096 199262 R identified by match to protein family HMM PF00589; prophage Sa05, site-specific recombinase, phage integrase family complement(198096..199262) Streptococcus pneumoniae Taiwan19F-14 7685946 YP_002741727.1 CDS SPT_0223 NC_012469.1 199347 200861 R identified by match to protein family HMM PF04326; divergent AAA domain family complement(199347..200861) Streptococcus pneumoniae Taiwan19F-14 7687016 YP_002741728.1 CDS SPT_0224 NC_012469.1 201022 201735 R identified by match to protein family HMM PF01381; putative DNA-binding phage protein complement(201022..201735) Streptococcus pneumoniae Taiwan19F-14 7687271 YP_002741729.1 CDS SPT_0225 NC_012469.1 201936 202118 D putative DNA-binding phage protein 201936..202118 Streptococcus pneumoniae Taiwan19F-14 7686974 YP_002741730.1 CDS SPT_0226 NC_012469.1 202134 202760 D hypothetical protein 202134..202760 Streptococcus pneumoniae Taiwan19F-14 7686363 YP_002741731.1 CDS SPT_0227 NC_012469.1 203189 203584 D hypothetical protein 203189..203584 Streptococcus pneumoniae Taiwan19F-14 7686779 YP_002741732.1 CDS SPT_0228 NC_012469.1 203581 203781 D hypothetical protein 203581..203781 Streptococcus pneumoniae Taiwan19F-14 7685289 YP_002741733.1 CDS SPT_0229 NC_012469.1 203783 203998 D hypothetical protein 203783..203998 Streptococcus pneumoniae Taiwan19F-14 7686782 YP_002741734.1 CDS SPT_0230 NC_012469.1 203995 204336 D phage protein 203995..204336 Streptococcus pneumoniae Taiwan19F-14 7686223 YP_002741735.1 CDS SPT_0231 NC_012469.1 204329 204610 D phage protein 204329..204610 Streptococcus pneumoniae Taiwan19F-14 7686517 YP_002741736.1 CDS SPT_0232 NC_012469.1 204745 205611 D identified by match to protein family HMM PF08708; phage protein 204745..205611 Streptococcus pneumoniae Taiwan19F-14 7686451 YP_002741737.1 CDS SPT_0233 NC_012469.1 205664 207133 D identified by match to protein family HMM PF08706; match to protein family HMM TIGR01613; prophage Sa05, DNA primase, P4 family 205664..207133 Streptococcus pneumoniae Taiwan19F-14 7685890 YP_002741738.1 CDS SPT_0234 NC_012469.1 207486 207653 D identified by glimmer; putative; hypothetical protein 207486..207653 Streptococcus pneumoniae Taiwan19F-14 7686546 YP_002741739.1 CDS SPT_0235 NC_012469.1 207737 208267 D phage protein 207737..208267 Streptococcus pneumoniae Taiwan19F-14 7685858 YP_002741740.1 CDS SPT_0236 NC_012469.1 208716 208847 D phage protein 208716..208847 Streptococcus pneumoniae Taiwan19F-14 7686720 YP_002741741.1 CDS SPT_0237 NC_012469.1 210043 210462 D identified by match to protein family HMM PF08281; phage protein 210043..210462 Streptococcus pneumoniae Taiwan19F-14 7685527 YP_002741742.1 CDS uvrA NC_012469.1 210951 213782 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 210951..213782 Streptococcus pneumoniae Taiwan19F-14 7685760 YP_002741743.1 CDS SPT_0239 NC_012469.1 213775 214836 D identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase 213775..214836 Streptococcus pneumoniae Taiwan19F-14 7686419 YP_002741744.1 CDS spxA NC_012469.1 214968 215366 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 214968..215366 Streptococcus pneumoniae Taiwan19F-14 7685442 YP_002741745.1 CDS SPT_0241 NC_012469.1 215432 216001 D lipoprotein, putative 215432..216001 Streptococcus pneumoniae Taiwan19F-14 7685288 YP_002741746.1 CDS SPT_0242 NC_012469.1 216088 216354 D identified by match to protein family HMM PF06135; hypothetical protein 216088..216354 Streptococcus pneumoniae Taiwan19F-14 7686618 YP_002741747.1 CDS SPT_0243 NC_012469.1 216358 216777 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 216358..216777 Streptococcus pneumoniae Taiwan19F-14 7685839 YP_002741748.1 CDS SPT_0244 NC_012469.1 216793 217098 D identified by match to protein family HMM PF06949; hypothetical protein 216793..217098 Streptococcus pneumoniae Taiwan19F-14 7687197 YP_002741749.1 CDS SPT_0245 NC_012469.1 217406 218656 D identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; dihydrofolate:folylpolyglutamate synthetase 217406..218656 Streptococcus pneumoniae Taiwan19F-14 7685841 YP_002741750.1 CDS SPT_0246 NC_012469.1 218740 219195 D lipoprotein, putative 218740..219195 Streptococcus pneumoniae Taiwan19F-14 7686516 YP_002741751.1 CDS SPT_0247 NC_012469.1 219341 220873 D identified by match to protein family HMM PF00614; cardiolipin synthase 219341..220873 Streptococcus pneumoniae Taiwan19F-14 7685741 YP_002741752.1 CDS SPT_0248 NC_012469.1 221131 222669 D competence-induced protein Ccs4 221131..222669 Streptococcus pneumoniae Taiwan19F-14 7687282 YP_002741753.1 CDS nrdD NC_012469.1 222789 224996 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 222789..224996 Streptococcus pneumoniae Taiwan19F-14 7685533 YP_002741754.1 CDS SPT_0250 NC_012469.1 225028 225168 D anaerobic ribonucleoside-triphosphate reductase 225028..225168 Streptococcus pneumoniae Taiwan19F-14 7687087 YP_002741755.1 CDS SPT_0251 NC_012469.1 225180 225320 D hypothetical protein 225180..225320 Streptococcus pneumoniae Taiwan19F-14 7686593 YP_002741756.1 CDS SPT_0252 NC_012469.1 225364 225870 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 225364..225870 Streptococcus pneumoniae Taiwan19F-14 7685518 YP_002741757.1 CDS nrdG NC_012469.1 225863 226453 D identified by match to protein family HMM PF04055; match to protein family HMM TIGR02491; anaerobic ribonucleoside-triphosphate reductase activating protein 225863..226453 Streptococcus pneumoniae Taiwan19F-14 7685331 YP_002741758.1 CDS SPT_0254 NC_012469.1 226450 227067 D identified by match to protein family HMM PF00485; phosphoribulokinase / Uridine kinase family 226450..227067 Streptococcus pneumoniae Taiwan19F-14 7686105 YP_002741759.1 CDS rpsJ NC_012469.1 227333 227641 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 227333..227641 Streptococcus pneumoniae Taiwan19F-14 7685805 YP_002741760.1 CDS rplC NC_012469.1 227858 228484 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 227858..228484 Streptococcus pneumoniae Taiwan19F-14 7687330 YP_002741761.1 CDS rplD NC_012469.1 228509 229132 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 228509..229132 Streptococcus pneumoniae Taiwan19F-14 7687312 YP_002741762.1 CDS rplW NC_012469.1 229132 229428 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 229132..229428 Streptococcus pneumoniae Taiwan19F-14 7686477 YP_002741763.1 CDS rplB NC_012469.1 229446 230279 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 229446..230279 Streptococcus pneumoniae Taiwan19F-14 7685222 YP_002741764.1 CDS rpsS NC_012469.1 230383 230664 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 230383..230664 Streptococcus pneumoniae Taiwan19F-14 7687195 YP_002741765.1 CDS rplV NC_012469.1 230676 231020 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 230676..231020 Streptococcus pneumoniae Taiwan19F-14 7687163 YP_002741766.1 CDS rpsC NC_012469.1 231033 231686 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 231033..231686 Streptococcus pneumoniae Taiwan19F-14 7685281 YP_002741767.1 CDS rplP NC_012469.1 231690 232103 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 231690..232103 Streptococcus pneumoniae Taiwan19F-14 7687018 YP_002741768.1 CDS rpmC NC_012469.1 232113 232319 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 232113..232319 Streptococcus pneumoniae Taiwan19F-14 7686688 YP_002741769.1 CDS rpsQ NC_012469.1 232344 232604 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 232344..232604 Streptococcus pneumoniae Taiwan19F-14 7686000 YP_002741770.1 CDS rplN NC_012469.1 232630 232998 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 232630..232998 Streptococcus pneumoniae Taiwan19F-14 7686998 YP_002741771.1 CDS rplX NC_012469.1 233076 233381 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 233076..233381 Streptococcus pneumoniae Taiwan19F-14 7685682 YP_002741772.1 CDS rplE NC_012469.1 233405 233947 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 233405..233947 Streptococcus pneumoniae Taiwan19F-14 7685869 YP_002741773.1 CDS rpsN NC_012469.1 233965 234234 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 233965..234234 Streptococcus pneumoniae Taiwan19F-14 7686227 YP_002741774.1 CDS rpsH NC_012469.1 234519 234917 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 234519..234917 Streptococcus pneumoniae Taiwan19F-14 7686289 YP_002741775.1 CDS rplF NC_012469.1 235109 235645 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 235109..235645 Streptococcus pneumoniae Taiwan19F-14 7686364 YP_002741776.1 CDS rplR NC_012469.1 235729 236085 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 235729..236085 Streptococcus pneumoniae Taiwan19F-14 7685719 YP_002741777.1 CDS rpsE NC_012469.1 236103 236597 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 236103..236597 Streptococcus pneumoniae Taiwan19F-14 7685750 YP_002741778.1 CDS rpmD NC_012469.1 236611 236793 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 236611..236793 Streptococcus pneumoniae Taiwan19F-14 7687264 YP_002741779.1 CDS rplO NC_012469.1 236938 237378 D late assembly protein; 50S ribosomal protein L15 236938..237378 Streptococcus pneumoniae Taiwan19F-14 7687381 YP_002741780.1 CDS secY NC_012469.1 237391 238701 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 237391..238701 Streptococcus pneumoniae Taiwan19F-14 7685910 YP_002741781.1 CDS adk NC_012469.1 238852 239490 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 238852..239490 Streptococcus pneumoniae Taiwan19F-14 7686320 YP_002741782.1 CDS infA NC_012469.1 239607 239825 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 239607..239825 Streptococcus pneumoniae Taiwan19F-14 7687211 YP_002741783.1 CDS rpmJ NC_012469.1 239850 239966 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 239850..239966 Streptococcus pneumoniae Taiwan19F-14 7686183 YP_002741784.2 CDS SPT_0280 NC_012469.1 239984 >240298 D truncated; an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00416; ribosomal protein S13p/S18e, unverified frameshift 239984..>240298 Streptococcus pneumoniae Taiwan19F-14 7687403 YP_002741785.1 CDS rpsK NC_012469.1 240368 240751 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 240368..240751 Streptococcus pneumoniae Taiwan19F-14 7686228 YP_002741786.1 CDS rpoA NC_012469.1 240794 241729 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 240794..241729 Streptococcus pneumoniae Taiwan19F-14 7686834 YP_002741787.1 CDS rplQ NC_012469.1 241741 242127 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 241741..242127 Streptococcus pneumoniae Taiwan19F-14 7687303 YP_002741788.1 CDS SPT_0284 NC_012469.1 242392 242658 D ACT domain-containing protein; hypothetical protein 242392..242658 Streptococcus pneumoniae Taiwan19F-14 7686952 YP_002741789.1 CDS SPT_0285 NC_012469.1 242668 244005 D identified by match to protein family HMM PF05167; hypothetical protein 242668..244005 Streptococcus pneumoniae Taiwan19F-14 7685219 YP_002741790.1 CDS SPT_0286 NC_012469.1 244192 244941 D identified by match to protein family HMM PF00300; phosphoglycerate mutase 244192..244941 Streptococcus pneumoniae Taiwan19F-14 7686037 YP_002741791.1 CDS SPT_0289 NC_012469.1 246679 247770 R identified by match to protein family HMM PF00005; match to protein family HMM PF08402; Fe(3+) ions import ATP-binding protein FbpC complement(246679..247770) Streptococcus pneumoniae Taiwan19F-14 7685935 YP_002741792.1 CDS SPT_0292 NC_012469.1 249121 249318 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(249121..249318) Streptococcus pneumoniae Taiwan19F-14 7686953 YP_002741793.1 CDS SPT_0293 NC_012469.1 249393 250169 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494; pyruvate formate-lyase 3 complement(249393..250169) Streptococcus pneumoniae Taiwan19F-14 7685480 YP_002741794.1 CDS SPT_0294 NC_012469.1 250291 251037 D identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; putative HTH-type transcriptional regulator YciT 250291..251037 Streptococcus pneumoniae Taiwan19F-14 7687220 YP_002741795.1 CDS SPT_0295 NC_012469.1 251050 252030 D identified by match to protein family HMM PF04198; transcriptional regulator 251050..252030 Streptococcus pneumoniae Taiwan19F-14 7685925 YP_002741796.1 CDS SPT_0296 NC_012469.1 252225 252545 D identified by match to protein family HMM PF02255; phosphotransferase system sugar-specific eiia component 252225..252545 Streptococcus pneumoniae Taiwan19F-14 7685486 YP_002741797.1 CDS SPT_0297 NC_012469.1 252591 252899 D identified by match to protein family HMM PF02302; PTS system, IIB component 252591..252899 Streptococcus pneumoniae Taiwan19F-14 7685797 YP_002741798.1 CDS SPT_0298 NC_012469.1 252916 254214 D identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 252916..254214 Streptococcus pneumoniae Taiwan19F-14 7686737 YP_002741799.1 CDS SPT_0299 NC_012469.1 254365 256803 D identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774; pyruvate formate-lyase 254365..256803 Streptococcus pneumoniae Taiwan19F-14 7687317 YP_002741800.1 CDS SPT_0300 NC_012469.1 256822 257490 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 256822..257490 Streptococcus pneumoniae Taiwan19F-14 7685370 YP_002741801.1 CDS gldA NC_012469.1 257508 258596 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 257508..258596 Streptococcus pneumoniae Taiwan19F-14 7686510 YP_002741802.1 CDS leuS NC_012469.1 259051 261552 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 259051..261552 Streptococcus pneumoniae Taiwan19F-14 7685870 YP_002741803.1 CDS SPT_0303 NC_012469.1 261691 262533 D identified by glimmer; putative; hypothetical protein 261691..262533 Streptococcus pneumoniae Taiwan19F-14 7685979 YP_002741804.1 CDS SPT_0304 NC_012469.1 262589 263284 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 262589..263284 Streptococcus pneumoniae Taiwan19F-14 7686886 YP_002741805.1 CDS SPT_0305 NC_012469.1 263296 263712 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 263296..263712 Streptococcus pneumoniae Taiwan19F-14 7686502 YP_002741806.1 CDS ruvB NC_012469.1 264753 265751 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 264753..265751 Streptococcus pneumoniae Taiwan19F-14 7686959 YP_002741807.1 CDS uppS NC_012469.1 266535 267293 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 266535..267293 Streptococcus pneumoniae Taiwan19F-14 7687166 YP_002741808.1 CDS cdsA NC_012469.1 267302 268105 D identified by match to protein family HMM PF01148; phosphatidate cytidylyltransferase 267302..268105 Streptococcus pneumoniae Taiwan19F-14 7686390 YP_002741809.1 CDS rseP NC_012469.1 268127 269386 D identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; RIP metalloprotease RseP 268127..269386 Streptococcus pneumoniae Taiwan19F-14 7686149 YP_002741810.1 CDS proS NC_012469.1 269399 271252 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 269399..271252 Streptococcus pneumoniae Taiwan19F-14 7686880 YP_002741811.1 CDS SPT_0312 NC_012469.1 271352 272731 D identified by match to protein family HMM PF00232; 6-phospho-beta-glucosidase 271352..272731 Streptococcus pneumoniae Taiwan19F-14 7686732 YP_002741812.1 CDS glmS NC_012469.1 272923 274731 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 272923..274731 Streptococcus pneumoniae Taiwan19F-14 7687324 YP_002741813.1 CDS SPT_0314 NC_012469.1 274850 275899 D identified by match to protein family HMM PF00296; oxidoreductase 274850..275899 Streptococcus pneumoniae Taiwan19F-14 7685791 YP_002741814.1 CDS SPT_0315 NC_012469.1 275999 279796 R identified by match to protein family HMM PF00128; match to protein family HMM PF00746; match to protein family HMM PF02922; match to protein family HMM PF03714; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; match to protein family HMM TIGR02102; pullulanase, extracellular complement(275999..279796) Streptococcus pneumoniae Taiwan19F-14 7686814 YP_002741815.1 CDS rpsL NC_012469.1 280213 280626 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 280213..280626 Streptococcus pneumoniae Taiwan19F-14 7687185 YP_002741816.1 CDS rpsG NC_012469.1 280646 281116 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 280646..281116 Streptococcus pneumoniae Taiwan19F-14 7685233 YP_002741817.1 CDS fusA NC_012469.1 281541 283622 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 281541..283622 Streptococcus pneumoniae Taiwan19F-14 7685367 YP_002741818.1 CDS polC NC_012469.1 283726 288117 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 283726..288117 Streptococcus pneumoniae Taiwan19F-14 7687304 YP_002741819.1 CDS SPT_0320 NC_012469.1 288219 288482 D identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384; addiction module antitoxin, RelB/DinJ family 288219..288482 Streptococcus pneumoniae Taiwan19F-14 7687133 YP_002741820.1 CDS SPT_0321 NC_012469.1 288475 288753 D identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; DNA damage inducible protein 288475..288753 Streptococcus pneumoniae Taiwan19F-14 7685225 YP_002741821.1 CDS SPT_0322 NC_012469.1 288774 288926 D hypothetical protein 288774..288926 Streptococcus pneumoniae Taiwan19F-14 7685216 YP_002741822.1 CDS SPT_0323 NC_012469.1 288948 290189 D identified by match to protein family HMM PF02073; aminopeptidase PepS 288948..290189 Streptococcus pneumoniae Taiwan19F-14 7687066 YP_002741823.1 CDS SPT_0324 NC_012469.1 290199 290429 D identified by match to protein family HMM PF04226; integral membrane protein 290199..290429 Streptococcus pneumoniae Taiwan19F-14 7685989 YP_002741824.1 CDS SPT_0325 NC_012469.1 290652 291374 D identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A, putative 290652..291374 Streptococcus pneumoniae Taiwan19F-14 7686679 YP_002741825.1 CDS SPT_0326 NC_012469.1 291591 292925 D identified by match to protein family HMM PF03051; aminopeptidase C (Bleomycin hydrolase) 291591..292925 Streptococcus pneumoniae Taiwan19F-14 7685806 YP_002741826.1 CDS SPT_0327 NC_012469.1 292981 293892 R identified by match to protein family HMM PF03613; match to protein family HMM TIGR00828; PTS system, mannose/fructose/sorbose family, IID component complement(292981..293892) Streptococcus pneumoniae Taiwan19F-14 7685756 YP_002741827.1 CDS SPT_0328 NC_012469.1 293916 294719 R identified by match to protein family HMM PF03609; PTS system sorbose-specific IIc component complement(293916..294719) Streptococcus pneumoniae Taiwan19F-14 7685202 YP_002741828.1 CDS SPT_0329 NC_012469.1 294747 295736 R identified by match to protein family HMM PF03610; match to protein family HMM PF03830; mannose-specific phosphotransferase system component iiab complement(294747..295736) Streptococcus pneumoniae Taiwan19F-14 7685368 YP_002741829.1 CDS SPT_0330 NC_012469.1 295969 296988 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(295969..296988) Streptococcus pneumoniae Taiwan19F-14 7687071 YP_002741830.1 CDS SPT_0331 NC_012469.1 297097 297243 R identified by glimmer; putative; hypothetical protein complement(297097..297243) Streptococcus pneumoniae Taiwan19F-14 7686849 YP_002741831.1 CDS SPT_0332 NC_012469.1 297327 298139 R identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein complement(297327..298139) Streptococcus pneumoniae Taiwan19F-14 7686426 YP_002741832.1 CDS SPT_0333 NC_012469.1 298275 299747 D identified by match to protein family HMM PF00860; match to protein family HMM PF00916; inner membrane protein YicO 298275..299747 Streptococcus pneumoniae Taiwan19F-14 7686079 YP_002741833.1 CDS SPT_0334 NC_012469.1 299800 300507 D identified by match to protein family HMM PF02517; caax amino protease family protein 299800..300507 Streptococcus pneumoniae Taiwan19F-14 7686254 YP_002741834.1 CDS folP NC_012469.1 300601 301578 D identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 300601..301578 Streptococcus pneumoniae Taiwan19F-14 7686560 YP_002741835.1 CDS SPT_0336 NC_012469.1 301580 302902 D identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; folylpolyglutamate synthase (folylpoly-gamma-glutamatesynthetase) (fpgs) (tetrahydrofolate synthase)(tetrahydrofolylpolyglutamate synthase) 301580..302902 Streptococcus pneumoniae Taiwan19F-14 7686831 YP_002741836.1 CDS folE NC_012469.1 302883 303437 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 302883..303437 Streptococcus pneumoniae Taiwan19F-14 7686731 YP_002741837.1 CDS SPT_0338 NC_012469.1 303480 304292 D identified by match to protein family HMM PF01288; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; match to protein family HMM TIGR01498; bifunctional folate synthesis protein 303480..304292 Streptococcus pneumoniae Taiwan19F-14 7686359 YP_002741838.1 CDS SPT_0339 NC_012469.1 304337 304654 R hypothetical protein complement(304337..304654) Streptococcus pneumoniae Taiwan19F-14 7685420 YP_002741839.1 CDS rplM NC_012469.1 305010 305456 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 305010..305456 Streptococcus pneumoniae Taiwan19F-14 7686367 YP_002741840.1 CDS rpsI NC_012469.1 305475 305867 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 305475..305867 Streptococcus pneumoniae Taiwan19F-14 7686605 YP_002741841.1 CDS SPT_0342 NC_012469.1 305976 307196 R identified by match to protein family HMM PF00589; integrase/recombinase, phage integrase family complement(305976..307196) Streptococcus pneumoniae Taiwan19F-14 7686716 YP_002741842.1 CDS SPT_0343 NC_012469.1 307238 307507 R identified by match to protein family HMM PF05930; match to protein family HMM TIGR01764; transcriptional regulator, AlpA family complement(307238..307507) Streptococcus pneumoniae Taiwan19F-14 7687100 YP_002741843.1 CDS SPT_0344 NC_012469.1 307515 308309 R Rep protein complement(307515..308309) Streptococcus pneumoniae Taiwan19F-14 7686883 YP_002741844.1 CDS SPT_0345 NC_012469.1 308481 309254 R identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein complement(308481..309254) Streptococcus pneumoniae Taiwan19F-14 7685494 YP_002741845.1 CDS SPT_0346 NC_012469.1 309329 310057 R identified by match to protein family HMM PF00149; Ser/Thr protein phosphatase family protein complement(309329..310057) Streptococcus pneumoniae Taiwan19F-14 7686940 YP_002741846.1 CDS SPT_0347 NC_012469.1 310484 311803 R identified by match to protein family HMM PF01580; putative otitis media-associated H10 complement(310484..311803) Streptococcus pneumoniae Taiwan19F-14 7687144 YP_002741847.1 CDS SPT_0348 NC_012469.1 311880 312350 R hypothetical protein complement(311880..312350) Streptococcus pneumoniae Taiwan19F-14 7686787 YP_002741848.1 CDS SPT_0349 NC_012469.1 312363 312950 R hypothetical protein complement(312363..312950) Streptococcus pneumoniae Taiwan19F-14 7685302 YP_002741849.1 CDS SPT_0350 NC_012469.1 313508 314119 R identified by glimmer; putative; hypothetical protein complement(313508..314119) Streptococcus pneumoniae Taiwan19F-14 7686110 YP_002741850.1 CDS SPT_0351 NC_012469.1 314166 314561 R hypothetical protein complement(314166..314561) Streptococcus pneumoniae Taiwan19F-14 7685706 YP_002741851.1 CDS SPT_0352 NC_012469.1 315334 315516 D Spn1, transposase Orf2 315334..315516 Streptococcus pneumoniae Taiwan19F-14 7685515 YP_002741852.1 CDS SPT_0353 NC_012469.1 315672 316010 D identified by match to protein family HMM PF03992; antibiotic biosynthesis monooxygenase 315672..316010 Streptococcus pneumoniae Taiwan19F-14 7685538 YP_002741853.1 CDS celA NC_012469.1 316200 317636 D converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 316200..317636 Streptococcus pneumoniae Taiwan19F-14 7686269 YP_002741854.1 CDS SPT_0355 NC_012469.1 317688 317927 D identified by match to protein family HMM PF03083; glutathione synthetase 317688..317927 Streptococcus pneumoniae Taiwan19F-14 7687191 YP_002741855.1 CDS celB NC_012469.1 318057 318371 D required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIB component 318057..318371 Streptococcus pneumoniae Taiwan19F-14 7685822 YP_002741856.1 CDS SPT_0357 NC_012469.1 318495 320468 D identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; transcription antiterminator BglG family 318495..320468 Streptococcus pneumoniae Taiwan19F-14 7687217 YP_002741857.1 CDS celC NC_012469.1 320478 320792 D required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIA component 320478..320792 Streptococcus pneumoniae Taiwan19F-14 7685708 YP_002741858.1 CDS SPT_0359 NC_012469.1 320823 321329 D hypothetical protein 320823..321329 Streptococcus pneumoniae Taiwan19F-14 7685505 YP_002741859.1 CDS celD NC_012469.1 321409 322755 D required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIC component 321409..322755 Streptococcus pneumoniae Taiwan19F-14 7685409 YP_002741860.1 CDS SPT_0361 NC_012469.1 323136 323312 D hypothetical protein 323136..323312 Streptococcus pneumoniae Taiwan19F-14 7687365 YP_002741861.1 CDS SPT_0362 NC_012469.1 323713 325926 D identified by match to protein family HMM PF01055; glycosyl hydrolase, family 31 323713..325926 Streptococcus pneumoniae Taiwan19F-14 7687050 YP_002741862.1 CDS SPT_0363 NC_012469.1 326148 326624 R identified by match to protein family HMM PF00255; peroxiredoxin Hyr1 (hydrogen peroxide resistanceprotein 1) (oxidant receptor peroxidase 1) (glutathione peroxidase 3)(phospholipid hydroperoxide glutathione peroxidase 3) (phgpx3) complement(326148..326624) Streptococcus pneumoniae Taiwan19F-14 7687399 YP_002741863.1 CDS SPT_0364 NC_012469.1 326847 330050 D identified by match to protein family HMM PF00746; match to protein family HMM PF02018; match to protein family HMM PF02278; match to protein family HMM PF02884; match to protein family HMM PF08124; match to protein family HMM TIGR01167; hyaluronate lyase 326847..330050 Streptococcus pneumoniae Taiwan19F-14 7686987 YP_002741864.1 CDS SPT_0366 NC_012469.1 331151 331780 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(331151..331780) Streptococcus pneumoniae Taiwan19F-14 7686608 YP_002741865.1 CDS SPT_0367 NC_012469.1 331790 332791 R identified by match to protein family HMM PF00294; 2-keto-3-deoxygluconate kinase complement(331790..332791) Streptococcus pneumoniae Taiwan19F-14 7685693 YP_002741866.1 CDS SPT_0368 NC_012469.1 332822 333463 R identified by match to protein family HMM PF02502; hypothetical protein complement(332822..333463) Streptococcus pneumoniae Taiwan19F-14 7686455 YP_002741867.1 CDS SPT_0369 NC_012469.1 333482 334297 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(333482..334297) Streptococcus pneumoniae Taiwan19F-14 7687327 YP_002741868.1 CDS SPT_0370 NC_012469.1 334569 335003 D identified by match to protein family HMM PF03610; phosphotransferase system sugar-specific EII component 334569..335003 Streptococcus pneumoniae Taiwan19F-14 7686670 YP_002741869.1 CDS SPT_0371 NC_012469.1 335015 336205 D identified by match to protein family HMM PF07470; unsaturated glucuronyl hydrolase (UGL) (Glycuronidase)(Unsaturated uronic acid hydrolase) (Glycosaminoglycan hydrolase) 335015..336205 Streptococcus pneumoniae Taiwan19F-14 7687266 YP_002741870.1 CDS SPT_0372 NC_012469.1 336216 336707 D identified by match to protein family HMM PF03830; N-acetylgalactosamine-specific phosphotransferase enzyme iib component2 (pts system n-acetylgalactosamine-specific eiibcomponent 2) (eiib-aga') 336216..336707 Streptococcus pneumoniae Taiwan19F-14 7685437 YP_002741871.1 CDS SPT_0373 NC_012469.1 336722 337501 D identified by match to protein family HMM PF03609; phosphotransferase system sugar-specific EII component 336722..337501 Streptococcus pneumoniae Taiwan19F-14 7685338 YP_002741872.1 CDS SPT_0374 NC_012469.1 337488 338306 D identified by match to protein family HMM PF03613; PTS system, IID component 337488..338306 Streptococcus pneumoniae Taiwan19F-14 7685737 YP_002741873.1 CDS SPT_0375 NC_012469.1 338306 338599 D preprotein translocase, YajC subunit 338306..338599 Streptococcus pneumoniae Taiwan19F-14 7686391 YP_002741874.1 CDS SPT_0376 NC_012469.1 338621 340522 D identified by match to protein family HMM PF07940; oligohyaluronate lyase 338621..340522 Streptococcus pneumoniae Taiwan19F-14 7685485 YP_002741875.1 CDS SPT_0377 NC_012469.1 340582 341583 D identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar binding transcriptional regulator RegR 340582..341583 Streptococcus pneumoniae Taiwan19F-14 7686725 YP_002741876.1 CDS SPT_0378 NC_012469.1 341640 341762 D identified by glimmer; putative; hypothetical protein 341640..341762 Streptococcus pneumoniae Taiwan19F-14 7687235 YP_002741877.1 CDS SPT_0379 NC_012469.1 341854 342432 R identified by glimmer; putative; hypothetical protein complement(341854..342432) Streptococcus pneumoniae Taiwan19F-14 7686470 YP_002741878.1 CDS SPT_0380 NC_012469.1 342459 342590 R identified by glimmer; putative; hypothetical protein complement(342459..342590) Streptococcus pneumoniae Taiwan19F-14 7686069 YP_002741879.1 CDS SPT_0381 NC_012469.1 342658 342792 R identified by glimmer; putative; hypothetical protein complement(342658..342792) Streptococcus pneumoniae Taiwan19F-14 7686690 YP_002741880.1 CDS SPT_0382 NC_012469.1 342796 343338 R hypothetical protein complement(342796..343338) Streptococcus pneumoniae Taiwan19F-14 7687392 YP_002741881.1 CDS SPT_0383 NC_012469.1 343354 343548 R identified by match to protein family HMM PF01381; hypothetical protein complement(343354..343548) Streptococcus pneumoniae Taiwan19F-14 7686572 YP_002741882.1 CDS mraW NC_012469.1 343714 344664 D identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 343714..344664 Streptococcus pneumoniae Taiwan19F-14 7685685 YP_002741883.1 CDS ftsL NC_012469.1 344677 344994 D identified by match to protein family HMM TIGR02209; cell division protein FtsL 344677..344994 Streptococcus pneumoniae Taiwan19F-14 7685723 YP_002741884.1 CDS SPT_0386 NC_012469.1 344998 347250 D identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; penicillin-binding protein 2x 344998..347250 Streptococcus pneumoniae Taiwan19F-14 7687161 YP_002741885.1 CDS mraY NC_012469.1 347252 348232 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 347252..348232 Streptococcus pneumoniae Taiwan19F-14 7685541 YP_002741886.1 CDS SPT_0388 NC_012469.1 348796 350901 D identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; ATP-dependent Clp protease ATP-binding subunit ClpL 348796..350901 Streptococcus pneumoniae Taiwan19F-14 7685957 YP_002741887.1 CDS luxS NC_012469.1 351196 351678 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(351196..351678) Streptococcus pneumoniae Taiwan19F-14 7685557 YP_002741888.1 CDS SPT_0390 NC_012469.1 351773 353257 R identified by match to protein family HMM PF08903; hypothetical protein complement(351773..353257) Streptococcus pneumoniae Taiwan19F-14 7686207 YP_002741889.1 CDS SPT_0391 NC_012469.1 353410 355017 D identified by match to protein family HMM PF00128; trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase) 353410..355017 Streptococcus pneumoniae Taiwan19F-14 7686271 YP_002741890.1 CDS SPT_0392 NC_012469.1 356437 357882 D identified by match to protein family HMM PF02916; match to protein family HMM PF03816; match to protein family HMM TIGR00350; integral membrane regulatory protein Wzg 356437..357882 Streptococcus pneumoniae Taiwan19F-14 7686312 YP_002741891.1 CDS SPT_0393 NC_012469.1 357884 358615 D identified by match to protein family HMM PF02811; tyrosine-protein phosphatase CpsB 357884..358615 Streptococcus pneumoniae Taiwan19F-14 7685512 YP_002741892.1 CDS SPT_0394 NC_012469.1 358624 359316 D identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006; capsular polysaccharide biosynthesis protein CpsC 358624..359316 Streptococcus pneumoniae Taiwan19F-14 7686211 YP_002741893.1 CDS SPT_0395 NC_012469.1 359326 360009 D identified by match to protein family HMM TIGR01007; tyrosine-protein kinase CpsD 359326..360009 Streptococcus pneumoniae Taiwan19F-14 7686356 YP_002741894.1 CDS SPT_0396 NC_012469.1 360394 361392 D identified by match to protein family HMM PF02397; match to protein family HMM TIGR03025; galactosyl transferase CpsE 360394..361392 Streptococcus pneumoniae Taiwan19F-14 7687156 YP_002741895.1 CDS SPT_0397 NC_012469.1 361396 362139 D identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696; UDP-N-acetyl-D-mannosamine transferase 361396..362139 Streptococcus pneumoniae Taiwan19F-14 7686890 YP_002741896.1 CDS SPT_0398 NC_012469.1 362136 362960 D identified by match to protein family HMM PF04991; 31.6 kDa cps19fG gene product 362136..362960 Streptococcus pneumoniae Taiwan19F-14 7685904 YP_002741897.1 CDS SPT_0399 NC_012469.1 362962 363840 D identified by match to protein family HMM PF00535; putative rhamnosyl transferase 362962..363840 Streptococcus pneumoniae Taiwan19F-14 7686937 YP_002741898.1 CDS SPT_0400 NC_012469.1 363841 365178 D polysaccharide polymerase Cps19aI 363841..365178 Streptococcus pneumoniae Taiwan19F-14 7685947 YP_002741899.1 CDS SPT_0401 NC_012469.1 365201 366622 D flippase Wzx 365201..366622 Streptococcus pneumoniae Taiwan19F-14 7685648 YP_002741900.1 CDS SPT_0402 NC_012469.1 366686 367774 D identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase 366686..367774 Streptococcus pneumoniae Taiwan19F-14 7686401 YP_002741901.1 CDS rfbA NC_012469.1 367813 368682 D identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207; glucose-1-phosphate thymidylyltransferase 367813..368682 Streptococcus pneumoniae Taiwan19F-14 7686865 YP_002741902.1 CDS SPT_0404 NC_012469.1 368683 369279 D identified by match to protein family HMM PF00908; dTDP-4-dehydrorhamnose 3,5-epimerase 368683..369279 Streptococcus pneumoniae Taiwan19F-14 7687296 YP_002741903.1 CDS rfbB NC_012469.1 369289 370338 D identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181; dTDP-glucose 4,6-dehydratase 369289..370338 Streptococcus pneumoniae Taiwan19F-14 7686116 YP_002741904.1 CDS rfbD NC_012469.1 370404 371255 D identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01214; dTDP-4-dehydrorhamnose reductase 370404..371255 Streptococcus pneumoniae Taiwan19F-14 7686156 YP_002741905.1 CDS SPT_0408 NC_012469.1 372400 372522 R hypothetical protein complement(372400..372522) Streptococcus pneumoniae Taiwan19F-14 7686070 YP_002741906.1 CDS SPT_0410 NC_012469.1 372724 374706 D identified by match to protein family HMM PF00496; oligopeptide binding protein 372724..374706 Streptococcus pneumoniae Taiwan19F-14 7686066 YP_002741907.1 CDS SPT_0411 NC_012469.1 375007 380310 D identified by match to protein family HMM PF00754; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; endo-alpha-N-acetylgalactosaminidase 375007..380310 Streptococcus pneumoniae Taiwan19F-14 7685213 YP_002741908.1 CDS SPT_0412 NC_012469.1 380476 382635 R identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1a complement(380476..382635) Streptococcus pneumoniae Taiwan19F-14 7686147 YP_002741909.1 CDS recU NC_012469.1 382632 383228 R functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease complement(382632..383228) Streptococcus pneumoniae Taiwan19F-14 7686341 YP_002741910.1 CDS SPT_0414 NC_012469.1 383295 383822 D identified by match to protein family HMM PF06908; hypothetical protein 383295..383822 Streptococcus pneumoniae Taiwan19F-14 7685999 YP_002741911.1 CDS SPT_0415 NC_012469.1 383892 384233 D identified by match to protein family HMM PF05103; cell division initiation protein 383892..384233 Streptococcus pneumoniae Taiwan19F-14 7687034 YP_002741912.1 CDS SPT_0416 NC_012469.1 384719 385876 D identified by match to protein family HMM PF01170; methyltransferase 384719..385876 Streptococcus pneumoniae Taiwan19F-14 7685560 YP_002741913.1 CDS SPT_0417 NC_012469.1 385889 387283 D hypothetical protein 385889..387283 Streptococcus pneumoniae Taiwan19F-14 7687255 YP_002741914.1 CDS gnd NC_012469.1 387359 388783 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 387359..388783 Streptococcus pneumoniae Taiwan19F-14 7685671 YP_002741915.1 CDS SPT_0419 NC_012469.1 388795 389484 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator 388795..389484 Streptococcus pneumoniae Taiwan19F-14 7687055 YP_002741916.1 CDS SPT_0420 NC_012469.1 389582 390544 D identified by match to protein family HMM PF01473; choline-binding protein F 389582..390544 Streptococcus pneumoniae Taiwan19F-14 7685317 YP_002741917.1 CDS SPT_0421 NC_012469.1 390563 391561 D identified by match to protein family HMM PF01473; choline binding protein J 390563..391561 Streptococcus pneumoniae Taiwan19F-14 7686568 YP_002741918.1 CDS SPT_0422 NC_012469.1 391679 392911 R identified by match to protein family HMM PF07690; transporter, major facilitator family protein complement(391679..392911) Streptococcus pneumoniae Taiwan19F-14 7685425 YP_002741919.1 CDS SPT_0423 NC_012469.1 392954 393373 R identified by glimmer; putative; hypothetical protein complement(392954..393373) Streptococcus pneumoniae Taiwan19F-14 7685528 YP_002741920.1 CDS SPT_0424 NC_012469.1 393441 393779 R identified by glimmer; putative; hypothetical protein complement(393441..393779) Streptococcus pneumoniae Taiwan19F-14 7686760 YP_002741921.1 CDS SPT_0425 NC_012469.1 394649 394771 D identified by match to protein family HMM PF01473; choline-binding protein F 394649..394771 Streptococcus pneumoniae Taiwan19F-14 7685896 YP_002741922.1 CDS mvk NC_012469.1 394893 395771 D identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR00549; mevalonate kinase 394893..395771 Streptococcus pneumoniae Taiwan19F-14 7686527 YP_002741923.1 CDS mvaD NC_012469.1 395753 396706 D identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01240; diphosphomevalonate decarboxylase 395753..396706 Streptococcus pneumoniae Taiwan19F-14 7685832 YP_002741924.1 CDS SPT_0428 NC_012469.1 396693 397700 D identified by match to protein family HMM PF00288; match to protein family HMM PF08544; match to protein family HMM TIGR01220; phosphomevalonate kinase 396693..397700 Streptococcus pneumoniae Taiwan19F-14 7686057 YP_002741925.1 CDS fni NC_012469.1 397684 398694 D catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 397684..398694 Streptococcus pneumoniae Taiwan19F-14 7686941 YP_002741926.1 CDS SPT_0430 NC_012469.1 398772 399470 D hypothetical protein 398772..399470 Streptococcus pneumoniae Taiwan19F-14 7685915 YP_002741927.1 CDS SPT_0431 NC_012469.1 399467 400462 D identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase 399467..400462 Streptococcus pneumoniae Taiwan19F-14 7686013 YP_002741928.1 CDS SPT_0432 NC_012469.1 400476 401108 D identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281; response regulator 400476..401108 Streptococcus pneumoniae Taiwan19F-14 7686672 YP_002741929.1 CDS SPT_0433 NC_012469.1 401109 401255 D identified by glimmer; putative; hypothetical protein 401109..401255 Streptococcus pneumoniae Taiwan19F-14 7686153 YP_002741930.1 CDS SPT_0435 NC_012469.1 401702 401878 D identified by glimmer; putative; hypothetical protein 401702..401878 Streptococcus pneumoniae Taiwan19F-14 7685667 YP_002741931.1 CDS SPT_0436 NC_012469.1 402028 402942 D identified by match to protein family HMM PF00089; choline binding protein G 402028..402942 Streptococcus pneumoniae Taiwan19F-14 7686607 YP_002741932.1 CDS SPT_0437 NC_012469.1 403235 403600 D integrase 403235..403600 Streptococcus pneumoniae Taiwan19F-14 7686049 YP_002741933.1 CDS tig NC_012469.1 403794 405077 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 403794..405077 Streptococcus pneumoniae Taiwan19F-14 7686809 YP_002741934.1 CDS SPT_0439 NC_012469.1 405125 407491 R identified by match to protein family HMM TIGR01448; helicase, RecD/TraA family complement(405125..407491) Streptococcus pneumoniae Taiwan19F-14 7687061 YP_002741935.1 CDS lepB1 NC_012469.1 407619 408233 R identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase I complement(407619..408233) Streptococcus pneumoniae Taiwan19F-14 7687128 YP_002741936.1 CDS rnhC NC_012469.1 408237 409118 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII complement(408237..409118) Streptococcus pneumoniae Taiwan19F-14 7685523 YP_002741937.1 CDS SPT_0442 NC_012469.1 409283 409507 D hypothetical protein 409283..409507 Streptococcus pneumoniae Taiwan19F-14 7685711 YP_002741938.1 CDS cvpA NC_012469.1 409504 410052 D identified by match to protein family HMM PF02674; CvpA family protein 409504..410052 Streptococcus pneumoniae Taiwan19F-14 7685888 YP_002741939.1 CDS SPT_0444 NC_012469.1 410156 412492 D identified by match to protein family HMM PF00488; match to protein family HMM PF01713; match to protein family HMM TIGR01069; MutS2 family protein 410156..412492 Streptococcus pneumoniae Taiwan19F-14 7686544 YP_002741940.1 CDS SPT_0445 NC_012469.1 412835 414151 D identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 412835..414151 Streptococcus pneumoniae Taiwan19F-14 7685410 YP_002741941.1 CDS SPT_0446 NC_012469.1 414369 414917 D identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778; macrophage infectivity potentiator protein 414369..414917 Streptococcus pneumoniae Taiwan19F-14 7685953 YP_002741942.1 CDS SPT_0447 NC_012469.1 415027 415926 D identified by match to protein family HMM PF03595; exfoliative toxin A 415027..415926 Streptococcus pneumoniae Taiwan19F-14 7686981 YP_002741943.1 CDS serS NC_012469.1 415951 417225 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(415951..417225) Streptococcus pneumoniae Taiwan19F-14 7687154 YP_002741944.1 CDS SPT_0449 NC_012469.1 417439 417810 R identified by match to protein family HMM PF06115; ManO complement(417439..417810) Streptococcus pneumoniae Taiwan19F-14 7685837 YP_002741945.1 CDS SPT_0450 NC_012469.1 417813 419177 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(417813..419177) Streptococcus pneumoniae Taiwan19F-14 7686871 YP_002741946.1 CDS SPT_0451 NC_012469.1 419355 419510 R hypothetical protein complement(419355..419510) Streptococcus pneumoniae Taiwan19F-14 7686840 YP_002741947.1 CDS SPT_0452 NC_012469.1 419502 420287 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 419502..420287 Streptococcus pneumoniae Taiwan19F-14 7687160 YP_002741948.1 CDS SPT_0453 NC_012469.1 420381 420815 D identified by match to protein family HMM PF01047; match to protein family HMM PF03965; transcriptional regulator 420381..420815 Streptococcus pneumoniae Taiwan19F-14 7685346 YP_002741949.1 CDS SPT_0454 NC_012469.1 420815 421789 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 420815..421789 Streptococcus pneumoniae Taiwan19F-14 7686936 YP_002741950.1 CDS acpP NC_012469.1 421849 422073 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 421849..422073 Streptococcus pneumoniae Taiwan19F-14 7685443 YP_002741951.1 CDS SPT_0456 NC_012469.1 422192 423166 D identified by match to protein family HMM PF03060; match to protein family HMM TIGR03151; enoyl-ACP reductase II 422192..423166 Streptococcus pneumoniae Taiwan19F-14 7686012 YP_002741952.1 CDS fabD NC_012469.1 423159 424079 D identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-acyl carrier protein transacylase 423159..424079 Streptococcus pneumoniae Taiwan19F-14 7686236 YP_002741953.1 CDS fabG NC_012469.1 424113 424844 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 424113..424844 Streptococcus pneumoniae Taiwan19F-14 7686124 YP_002741954.1 CDS fabF NC_012469.1 424866 426101 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 424866..426101 Streptococcus pneumoniae Taiwan19F-14 7686131 YP_002741955.1 CDS accB NC_012469.1 426104 426589 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 426104..426589 Streptococcus pneumoniae Taiwan19F-14 7687024 YP_002741956.1 CDS fabZ NC_012469.1 426586 427008 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 426586..427008 Streptococcus pneumoniae Taiwan19F-14 7685782 YP_002741957.1 CDS accC NC_012469.1 427020 428387 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 427020..428387 Streptococcus pneumoniae Taiwan19F-14 7687212 YP_002741958.1 CDS accD NC_012469.1 428424 429290 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 428424..429290 Streptococcus pneumoniae Taiwan19F-14 7686590 YP_002741959.1 CDS accA NC_012469.1 429287 430054 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 429287..430054 Streptococcus pneumoniae Taiwan19F-14 7685666 YP_002741960.1 CDS SPT_0465 NC_012469.1 430317 430502 D hypothetical protein 430317..430502 Streptococcus pneumoniae Taiwan19F-14 7685686 YP_002741961.1 CDS SPT_0466 NC_012469.1 430559 430693 D identified by glimmer; putative; hypothetical protein 430559..430693 Streptococcus pneumoniae Taiwan19F-14 7687040 YP_002741962.1 CDS SPT_0467 NC_012469.1 430843 430971 D identified by glimmer; putative; hypothetical protein 430843..430971 Streptococcus pneumoniae Taiwan19F-14 7687079 YP_002741963.1 CDS nusB NC_012469.1 431270 431692 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(431270..431692) Streptococcus pneumoniae Taiwan19F-14 7685497 YP_002741964.1 CDS SPT_0469 NC_012469.1 431685 432074 R identified by match to protein family HMM PF03780; general stress protein, Gls24 family complement(431685..432074) Streptococcus pneumoniae Taiwan19F-14 7686815 YP_002741965.1 CDS efp NC_012469.1 432096 432656 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(432096..432656) Streptococcus pneumoniae Taiwan19F-14 7686480 YP_002741966.1 CDS SPT_0471 NC_012469.1 432824 433009 D chlorohydrolase 432824..433009 Streptococcus pneumoniae Taiwan19F-14 7686554 YP_002741967.1 CDS SPT_0472 NC_012469.1 433034 434077 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; L-iditol 2-dehydrogenase complement(433034..434077) Streptococcus pneumoniae Taiwan19F-14 7685721 YP_002741968.1 CDS gatB NC_012469.1 434201 435643 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(434201..435643) Streptococcus pneumoniae Taiwan19F-14 7686771 YP_002741969.1 CDS gatA NC_012469.1 435643 437109 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(435643..437109) Streptococcus pneumoniae Taiwan19F-14 7686830 YP_002741970.1 CDS gatC NC_012469.1 437109 437411 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(437109..437411) Streptococcus pneumoniae Taiwan19F-14 7685380 YP_002741971.1 CDS prfC NC_012469.1 437624 439168 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 437624..439168 Streptococcus pneumoniae Taiwan19F-14 7685897 YP_002741972.1 CDS rpmB NC_012469.1 440196 440384 D required for 70S ribosome assembly; 50S ribosomal protein L28 440196..440384 Streptococcus pneumoniae Taiwan19F-14 7686071 YP_002741973.1 CDS SPT_0479 NC_012469.1 440541 440906 D identified by match to protein family HMM PF03780; alkaline shock protein 440541..440906 Streptococcus pneumoniae Taiwan19F-14 7685328 YP_002741974.1 CDS SPT_0480 NC_012469.1 440909 442576 D identified by match to protein family HMM PF02734; dihydroxyacetone kinase family protein 440909..442576 Streptococcus pneumoniae Taiwan19F-14 7685488 YP_002741975.1 CDS ilvB NC_012469.1 442776 444476 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 442776..444476 Streptococcus pneumoniae Taiwan19F-14 7686182 YP_002741976.1 CDS ilvH NC_012469.1 444469 444945 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 444469..444945 Streptococcus pneumoniae Taiwan19F-14 7685508 YP_002741977.1 CDS ilvC NC_012469.1 445011 446033 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 445011..446033 Streptococcus pneumoniae Taiwan19F-14 7685793 YP_002741978.1 CDS SPT_0484 NC_012469.1 446140 446376 D hypothetical protein 446140..446376 Streptococcus pneumoniae Taiwan19F-14 7686643 YP_002741979.1 CDS SPT_0485 NC_012469.1 446614 446970 D hypothetical protein 446614..446970 Streptococcus pneumoniae Taiwan19F-14 7686642 YP_002741980.1 CDS ilvA NC_012469.1 447020 448270 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 447020..448270 Streptococcus pneumoniae Taiwan19F-14 7686058 YP_002741981.1 CDS SPT_0487 NC_012469.1 448412 448600 D hypothetical protein 448412..448600 Streptococcus pneumoniae Taiwan19F-14 7685429 YP_002741982.1 CDS SPT_0488 NC_012469.1 449141 449356 D hypothetical protein 449141..449356 Streptococcus pneumoniae Taiwan19F-14 7687388 YP_002741983.1 CDS gltL NC_012469.1 449465 450205 R identified by match to protein family HMM PF00005; glutamate/aspartate ABC transporter, ATP-binding protein complement(449465..450205) Streptococcus pneumoniae Taiwan19F-14 7686424 YP_002741984.1 CDS SPT_0490 NC_012469.1 450205 451770 R identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein complement(450205..451770) Streptococcus pneumoniae Taiwan19F-14 7687037 YP_002741985.1 CDS SPT_0492 NC_012469.1 451908 453797 D hypothetical protein 451908..453797 Streptococcus pneumoniae Taiwan19F-14 7687183 YP_002741986.1 CDS SPT_0491 NC_012469.1 453794 453964 R hypothetical protein complement(453794..453964) Streptococcus pneumoniae Taiwan19F-14 7686984 YP_002741987.1 CDS SPT_0494 NC_012469.1 454844 454966 R identified by glimmer; putative; hypothetical protein complement(454844..454966) Streptococcus pneumoniae Taiwan19F-14 7685996 YP_002741988.1 CDS SPT_0495 NC_012469.1 455222 456067 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 455222..456067 Streptococcus pneumoniae Taiwan19F-14 7687027 YP_002741989.1 CDS SPT_0496 NC_012469.1 456060 456188 D hypothetical protein 456060..456188 Streptococcus pneumoniae Taiwan19F-14 7686145 YP_002741990.1 CDS SPT_0497 NC_012469.1 456214 457275 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(456214..457275) Streptococcus pneumoniae Taiwan19F-14 7686242 YP_002741991.1 CDS pflB NC_012469.1 457623 459947 D identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 457623..459947 Streptococcus pneumoniae Taiwan19F-14 7686660 YP_002741992.1 CDS SPT_0499 NC_012469.1 460005 461267 R identified by match to protein family HMM PF01610; transposase complement(460005..461267) Streptococcus pneumoniae Taiwan19F-14 7685293 YP_002741993.1 CDS SPT_0500 NC_012469.1 461532 463061 R identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08280; transcriptional regulator, putative complement(461532..463061) Streptococcus pneumoniae Taiwan19F-14 7687341 YP_002741994.1 CDS SPT_0501 NC_012469.1 463577 466237 D identified by match to protein family HMM PF00092; match to protein family HMM PF05738; cell wall surface anchor family protein 463577..466237 Streptococcus pneumoniae Taiwan19F-14 7686189 YP_002741995.1 CDS SPT_0503 NC_012469.1 466460 468457 D identified by match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167; cell wall surface anchor family protein 466460..468457 Streptococcus pneumoniae Taiwan19F-14 7685492 YP_002741996.1 CDS SPT_0502 NC_012469.1 468423 468725 R identified by glimmer; putative; hypothetical protein complement(468423..468725) Streptococcus pneumoniae Taiwan19F-14 7687221 YP_002741997.1 CDS SPT_0504 NC_012469.1 468774 469685 D identified by match to protein family HMM PF05738; match to protein family HMM TIGR01167; cell wall surface anchor family protein 468774..469685 Streptococcus pneumoniae Taiwan19F-14 7686321 YP_002741998.1 CDS SPT_0505 NC_012469.1 470024 470920 D identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase family protein 470024..470920 Streptococcus pneumoniae Taiwan19F-14 7685998 YP_002741999.1 CDS SPT_0506 NC_012469.1 470989 471807 D identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase family protein 470989..471807 Streptococcus pneumoniae Taiwan19F-14 7686624 YP_002742000.1 CDS SPT_0507 NC_012469.1 471836 472645 D identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase, putative 471836..472645 Streptococcus pneumoniae Taiwan19F-14 7686119 YP_002742001.1 CDS SPT_0511 NC_012469.1 474158 474307 R hypothetical protein complement(474158..474307) Streptococcus pneumoniae Taiwan19F-14 7685484 YP_002742002.1 CDS SPT_0512 NC_012469.1 474300 474584 R hypothetical protein complement(474300..474584) Streptococcus pneumoniae Taiwan19F-14 7687335 YP_002742003.1 CDS SPT_0513 NC_012469.1 475181 475351 R hypothetical protein complement(475181..475351) Streptococcus pneumoniae Taiwan19F-14 7685308 YP_002742004.1 CDS SPT_0514 NC_012469.1 476005 477228 R identified by match to protein family HMM PF00480; ROK family protein complement(476005..477228) Streptococcus pneumoniae Taiwan19F-14 7686740 YP_002742005.1 CDS SPT_0515 NC_012469.1 477395 478717 D identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; lichenan permease iic component (pts system lichenan-specific eiiccomponent) (eiic-lic) 477395..478717 Streptococcus pneumoniae Taiwan19F-14 7685621 YP_002742006.1 CDS SPT_0516 NC_012469.1 478719 480605 D hypothetical protein 478719..480605 Streptococcus pneumoniae Taiwan19F-14 7685381 YP_002742007.1 CDS SPT_0517 NC_012469.1 480773 481117 D identified by match to protein family HMM PF02255; lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) 480773..481117 Streptococcus pneumoniae Taiwan19F-14 7685224 YP_002742008.1 CDS lacG1 NC_012469.1 481127 482539 D catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 481127..482539 Streptococcus pneumoniae Taiwan19F-14 7685343 YP_002742009.1 CDS SPT_0519 NC_012469.1 482608 484287 D identified by match to protein family HMM PF02302; match to protein family HMM PF02378; pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) 482608..484287 Streptococcus pneumoniae Taiwan19F-14 7686104 YP_002742010.1 CDS SPT_0520 NC_012469.1 484413 485852 R identified by match to protein family HMM PF02386; potassium uptake protein, Trk family complement(484413..485852) Streptococcus pneumoniae Taiwan19F-14 7686916 YP_002742011.1 CDS trkA NC_012469.1 485856 487205 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(485856..487205) Streptococcus pneumoniae Taiwan19F-14 7686302 YP_002742012.1 CDS SPT_0522 NC_012469.1 487393 488241 D identified by match to protein family HMM PF01887; hypothetical protein 487393..488241 Streptococcus pneumoniae Taiwan19F-14 7685908 YP_002742013.1 CDS SPT_0523 NC_012469.1 488256 488804 D identified by match to protein family HMM PF07155; hypothetical protein 488256..488804 Streptococcus pneumoniae Taiwan19F-14 7687159 YP_002742014.1 CDS SPT_0524 NC_012469.1 488811 489068 D hypothetical protein 488811..489068 Streptococcus pneumoniae Taiwan19F-14 7686867 YP_002742015.1 CDS SPT_0525 NC_012469.1 489170 490852 D identified by match to protein family HMM PF00005; putative ABC transporter ATP-binding protein 489170..490852 Streptococcus pneumoniae Taiwan19F-14 7686143 YP_002742016.1 CDS SPT_0526 NC_012469.1 490837 491667 D identified by match to protein family HMM PF02361; cobalt transport family protein 490837..491667 Streptococcus pneumoniae Taiwan19F-14 7687130 YP_002742017.1 CDS SPT_0527 NC_012469.1 491860 492363 D identified by match to protein family HMM PF00588; RNA methyltransferase, TrmH family, group 2 491860..492363 Streptococcus pneumoniae Taiwan19F-14 7686898 YP_002742018.1 CDS SPT_0528 NC_012469.1 492816 493379 D hypothetical protein 492816..493379 Streptococcus pneumoniae Taiwan19F-14 7686064 YP_002742019.1 CDS SPT_0529 NC_012469.1 493393 494019 D identified by match to protein family HMM PF01569; PAP2 family protein 493393..494019 Streptococcus pneumoniae Taiwan19F-14 7686968 YP_002742020.1 CDS SPT_0530 NC_012469.1 494046 494435 D hypothetical protein 494046..494435 Streptococcus pneumoniae Taiwan19F-14 7687150 YP_002742021.1 CDS SPT_0531 NC_012469.1 494440 494889 D hypothetical protein 494440..494889 Streptococcus pneumoniae Taiwan19F-14 7686016 YP_002742022.1 CDS rpoE NC_012469.1 495017 495604 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 495017..495604 Streptococcus pneumoniae Taiwan19F-14 7686606 YP_002742023.1 CDS pyrG NC_012469.1 495994 497601 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 495994..497601 Streptococcus pneumoniae Taiwan19F-14 7686004 YP_002742024.1 CDS SPT_0534 NC_012469.1 498160 499791 R identified by match to protein family HMM PF01895; match to protein family HMM PF02690; match to protein family HMM TIGR00704; sodium-dependent phosphate transporter complement(498160..499791) Streptococcus pneumoniae Taiwan19F-14 7687053 YP_002742025.1 CDS SPT_0535 NC_012469.1 500152 505020 D identified by match to protein family HMM PF00746; match to protein family HMM PF00754; match to protein family HMM PF03644; match to protein family HMM PF07501; match to protein family HMM PF07523; match to protein family HMM PF07554; match to protein family HMM TIGR01167; endo-beta-N-acetylglucosaminidase D 500152..505020 Streptococcus pneumoniae Taiwan19F-14 7686194 YP_002742026.1 CDS pgk NC_012469.1 505110 506306 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 505110..506306 Streptococcus pneumoniae Taiwan19F-14 7687347 YP_002742027.1 CDS SPT_0537 NC_012469.1 506442 506969 D hypothetical protein 506442..506969 Streptococcus pneumoniae Taiwan19F-14 7686438 YP_002742028.1 CDS SPT_0538 NC_012469.1 507046 507402 D identified by match to protein family HMM PF00376; HTH-type transcriptional regulator GlnR 507046..507402 Streptococcus pneumoniae Taiwan19F-14 7686785 YP_002742029.1 CDS glnA NC_012469.1 507439 508785 D identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase, type I 507439..508785 Streptococcus pneumoniae Taiwan19F-14 7686610 YP_002742030.1 CDS SPT_0540 NC_012469.1 508881 509000 R hypothetical protein complement(508881..509000) Streptococcus pneumoniae Taiwan19F-14 7686662 YP_002742031.1 CDS SPT_0541 NC_012469.1 508965 509114 D identified by glimmer; putative; hypothetical protein 508965..509114 Streptococcus pneumoniae Taiwan19F-14 7685778 YP_002742032.1 CDS SPT_0543 NC_012469.1 509567 510847 D identified by match to protein family HMM PF01420; type I restriction enzyme specificity protein 509567..510847 Streptococcus pneumoniae Taiwan19F-14 7686650 YP_002742033.1 CDS SPT_0542 NC_012469.1 510795 512360 R identified by match to protein family HMM PF01420; type I site-specific deoxyribonuclease chain S complement(510795..512360) Streptococcus pneumoniae Taiwan19F-14 7686429 YP_002742034.1 CDS SPT_0544 NC_012469.1 512360 513823 R identified by match to protein family HMM PF02384; type I restriction enzyme complement(512360..513823) Streptococcus pneumoniae Taiwan19F-14 7685210 YP_002742035.1 CDS SPT_0545 NC_012469.1 513836 516169 R identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463; type I restriction-modification system, R subunit complement(513836..516169) Streptococcus pneumoniae Taiwan19F-14 7686914 YP_002742036.1 CDS SPT_0546 NC_012469.1 516520 516648 R hypothetical protein complement(516520..516648) Streptococcus pneumoniae Taiwan19F-14 7687254 YP_002742037.1 CDS SPT_0547 NC_012469.1 516777 517286 D hypothetical protein 516777..517286 Streptococcus pneumoniae Taiwan19F-14 7685825 YP_002742038.1 CDS hrcA NC_012469.1 517450 518484 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 517450..518484 Streptococcus pneumoniae Taiwan19F-14 7686547 YP_002742039.1 CDS grpE NC_012469.1 518511 519035 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 518511..519035 Streptococcus pneumoniae Taiwan19F-14 7685906 YP_002742040.1 CDS dnaK NC_012469.1 519515 521338 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 519515..521338 Streptococcus pneumoniae Taiwan19F-14 7685969 YP_002742041.1 CDS SPT_0551 NC_012469.1 521351 521704 D identified by glimmer; putative; hypothetical protein 521351..521704 Streptococcus pneumoniae Taiwan19F-14 7686007 YP_002742042.1 CDS dnaJ NC_012469.1 521909 523045 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 521909..523045 Streptococcus pneumoniae Taiwan19F-14 7685453 YP_002742043.1 CDS SPT_0553 NC_012469.1 523367 523561 R chlorohydrolase complement(523367..523561) Streptococcus pneumoniae Taiwan19F-14 7686268 YP_002742044.1 CDS SPT_0554 NC_012469.1 523723 524010 R hypothetical protein complement(523723..524010) Streptococcus pneumoniae Taiwan19F-14 7687202 YP_002742045.1 CDS SPT_0555 NC_012469.1 524020 524430 R identified by match to protein family HMM PF01230; histidine triad domain protein complement(524020..524430) Streptococcus pneumoniae Taiwan19F-14 7685912 YP_002742046.1 CDS SPT_0556 NC_012469.1 524498 525229 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 524498..525229 Streptococcus pneumoniae Taiwan19F-14 7686175 YP_002742047.1 CDS SPT_0557 NC_012469.1 525226 526275 D identified by match to protein family HMM PF05975; ABC transporter permease 525226..526275 Streptococcus pneumoniae Taiwan19F-14 7687090 YP_002742048.1 CDS SPT_0558 NC_012469.1 526443 526772 R BlpT protein, fusion complement(526443..526772) Streptococcus pneumoniae Taiwan19F-14 7686746 YP_002742049.1 CDS SPT_0559 NC_012469.1 527068 528414 R identified by match to protein family HMM PF01609; Spn1 transposase complement(527068..528414) Streptococcus pneumoniae Taiwan19F-14 7685662 YP_002742050.1 CDS SPT_0560 NC_012469.1 528756 529094 D identified by match to protein family HMM PF04397; BlpS protein 528756..529094 Streptococcus pneumoniae Taiwan19F-14 7686336 YP_002742051.1 CDS SPT_0561 NC_012469.1 529099 529836 D identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator 529099..529836 Streptococcus pneumoniae Taiwan19F-14 7686639 YP_002742052.1 CDS SPT_0562 NC_012469.1 529849 531189 D histidine kinase 529849..531189 Streptococcus pneumoniae Taiwan19F-14 7686631 YP_002742053.1 CDS SPT_0563 NC_012469.1 531429 532775 R identified by match to protein family HMM PF01609; Spn1 transposase complement(531429..532775) Streptococcus pneumoniae Taiwan19F-14 7685318 YP_002742054.1 CDS SPT_0564 NC_012469.1 532942 533097 R identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein complement(532942..533097) Streptococcus pneumoniae Taiwan19F-14 7687178 YP_002742055.1 CDS SPT_0565 NC_012469.1 533154 534515 R identified by match to protein family HMM TIGR01000; BlpC ABC transporter complement(533154..534515) Streptococcus pneumoniae Taiwan19F-14 7685454 YP_002742056.1 CDS SPT_0568 NC_012469.1 536059 536307 D identified by match to protein family HMM TIGR01847; hypothetical protein 536059..536307 Streptococcus pneumoniae Taiwan19F-14 7685414 YP_002742057.1 CDS SPT_0569 NC_012469.1 536323 536532 D identified by match to protein family HMM TIGR01847; bacteriocin-type signal sequence domain protein 536323..536532 Streptococcus pneumoniae Taiwan19F-14 7687373 YP_002742058.1 CDS SPT_0570 NC_012469.1 537734 538309 D identified by match to protein family HMM PF02517; ABC transporter ATP-binding protein 537734..538309 Streptococcus pneumoniae Taiwan19F-14 7687073 YP_002742059.1 CDS SPT_0571 NC_012469.1 538536 538724 D hypothetical protein 538536..538724 Streptococcus pneumoniae Taiwan19F-14 7687307 YP_002742060.1 CDS SPT_0572 NC_012469.1 538820 539158 D immunity protein BlpL 538820..539158 Streptococcus pneumoniae Taiwan19F-14 7687224 YP_002742061.1 CDS SPT_0576 NC_012469.1 540314 540547 D identified by match to protein family HMM TIGR01847; bacteriocin BlpM 540314..540547 Streptococcus pneumoniae Taiwan19F-14 7686500 YP_002742062.1 CDS SPT_0577 NC_012469.1 541056 541745 D BlpY protein 541056..541745 Streptococcus pneumoniae Taiwan19F-14 7685473 YP_002742063.1 CDS SPT_0579 NC_012469.1 542171 542782 D identified by match to protein family HMM PF02517; ABC transporter ATP-binding protein 542171..542782 Streptococcus pneumoniae Taiwan19F-14 7685995 YP_002742064.1 CDS SPT_0580 NC_012469.1 542943 543737 D identified by match to protein family HMM PF01636; phosphotransferase enzyme family 542943..543737 Streptococcus pneumoniae Taiwan19F-14 7686583 YP_002742065.1 CDS trmB NC_012469.1 543734 544369 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 543734..544369 Streptococcus pneumoniae Taiwan19F-14 7685638 YP_002742066.1 CDS SPT_0582 NC_012469.1 544495 544974 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 544495..544974 Streptococcus pneumoniae Taiwan19F-14 7686085 YP_002742067.1 CDS nusA NC_012469.1 545018 546154 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 545018..546154 Streptococcus pneumoniae Taiwan19F-14 7685714 YP_002742068.1 CDS SPT_0584 NC_012469.1 546176 546469 D identified by match to protein family HMM PF04296; putative chain a, hypothetical cytosolic protein coded by gene from nusainfb, ylxr homologue 546176..546469 Streptococcus pneumoniae Taiwan19F-14 7686503 YP_002742069.1 CDS SPT_0585 NC_012469.1 546462 546761 D identified by match to protein family HMM PF01248; hypothetical protein 546462..546761 Streptococcus pneumoniae Taiwan19F-14 7687096 YP_002742070.1 CDS infB NC_012469.1 546778 549570 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 546778..549570 Streptococcus pneumoniae Taiwan19F-14 7687047 YP_002742071.1 CDS rbfA NC_012469.1 549821 550171 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 549821..550171 Streptococcus pneumoniae Taiwan19F-14 7686021 YP_002742072.1 CDS SPT_0588 NC_012469.1 550450 551229 D hypothetical protein 550450..551229 Streptococcus pneumoniae Taiwan19F-14 7686420 YP_002742073.1 CDS SPT_0589 NC_012469.1 551231 551413 D hypothetical protein 551231..551413 Streptococcus pneumoniae Taiwan19F-14 7685441 YP_002742074.1 CDS SPT_0590 NC_012469.1 551410 551562 D hypothetical protein 551410..551562 Streptococcus pneumoniae Taiwan19F-14 7686792 YP_002742075.1 CDS SPT_0591 NC_012469.1 551692 551844 R identified by glimmer; putative; hypothetical protein complement(551692..551844) Streptococcus pneumoniae Taiwan19F-14 7685933 YP_002742076.1 CDS SPT_0592 NC_012469.1 551875 552108 D identified by match to protein family HMM PF08984; hypothetical protein 551875..552108 Streptococcus pneumoniae Taiwan19F-14 7685940 YP_002742077.1 CDS SPT_0593 NC_012469.1 552108 553442 D identified by match to protein family HMM PF01814; match to protein family HMM PF04282; hemerythrin HHE cation binding domain subfamily, putative 552108..553442 Streptococcus pneumoniae Taiwan19F-14 7687249 YP_002742078.1 CDS SPT_0594 NC_012469.1 553452 553706 D identified by match to protein family HMM PF08930; hypothetical protein 553452..553706 Streptococcus pneumoniae Taiwan19F-14 7685298 YP_002742079.1 CDS SPT_0595 NC_012469.1 553802 554197 D superfamily II helicase 553802..554197 Streptococcus pneumoniae Taiwan19F-14 7686813 YP_002742080.1 CDS SPT_0596 NC_012469.1 554610 555059 D identified by glimmer; putative; hypothetical protein 554610..555059 Streptococcus pneumoniae Taiwan19F-14 7685371 YP_002742081.1 CDS SPT_0597 NC_012469.1 555046 555606 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 555046..555606 Streptococcus pneumoniae Taiwan19F-14 7685249 YP_002742082.1 CDS SPT_0598 NC_012469.1 555606 556184 D shikimate kinase 555606..556184 Streptococcus pneumoniae Taiwan19F-14 7686091 YP_002742083.1 CDS valS NC_012469.1 556177 558828 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 556177..558828 Streptococcus pneumoniae Taiwan19F-14 7686882 YP_002742084.1 CDS SPT_0600 NC_012469.1 558909 559073 D hypothetical protein 558909..559073 Streptococcus pneumoniae Taiwan19F-14 7686483 YP_002742085.1 CDS SPT_0602 NC_012469.1 561106 561909 D identified by match to protein family HMM PF02661; Fic protein family 561106..561909 Streptococcus pneumoniae Taiwan19F-14 7686947 YP_002742086.1 CDS SPT_0603 NC_012469.1 562025 562858 R identified by match to protein family HMM PF00665; integrase core domain protein complement(562025..562858) Streptococcus pneumoniae Taiwan19F-14 7686133 YP_002742087.1 CDS SPT_0605 NC_012469.1 563356 563538 D hypothetical protein 563356..563538 Streptococcus pneumoniae Taiwan19F-14 7686790 YP_002742088.1 CDS SPT_0606 NC_012469.1 563838 564677 D transcription antiterminator LicT 563838..564677 Streptococcus pneumoniae Taiwan19F-14 7685803 YP_002742089.1 CDS SPT_0607 NC_012469.1 564695 566533 D pts system beta-glucoside-specific eiibca component (eiibca-bgl) (eii-bgl) 564695..566533 Streptococcus pneumoniae Taiwan19F-14 7687374 YP_002742090.1 CDS SPT_0608 NC_012469.1 566546 567961 D identified by match to protein family HMM PF00232; beta-glucosidase (Gentiobiase) (Cellobiase) (Beta-D-glucoside glucohydrolase) (Amygdalase) 566546..567961 Streptococcus pneumoniae Taiwan19F-14 7686713 YP_002742091.1 CDS pheS NC_012469.1 568511 569599 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 568511..569599 Streptococcus pneumoniae Taiwan19F-14 7685802 YP_002742092.1 CDS SPT_0610 NC_012469.1 569599 570108 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 569599..570108 Streptococcus pneumoniae Taiwan19F-14 7687075 YP_002742093.1 CDS pheT NC_012469.1 570185 572590 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 570185..572590 Streptococcus pneumoniae Taiwan19F-14 7685221 YP_002742094.1 CDS SPT_0612 NC_012469.1 572658 573659 R identified by match to protein family HMM PF03372; endonuclease/exonuclease/phosphatase family complement(572658..573659) Streptococcus pneumoniae Taiwan19F-14 7686374 YP_002742095.1 CDS SPT_0614 NC_012469.1 574335 574601 D identified by match to protein family HMM PF01381; helix-turn-helix domain protein 574335..574601 Streptococcus pneumoniae Taiwan19F-14 7686954 YP_002742096.1 CDS metE NC_012469.1 574862 577111 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 574862..577111 Streptococcus pneumoniae Taiwan19F-14 7686738 YP_002742097.1 CDS metF NC_012469.1 577175 578041 D identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 577175..578041 Streptococcus pneumoniae Taiwan19F-14 7686258 YP_002742098.1 CDS SPT_0617 NC_012469.1 578726 580939 D identified by match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase/polyadenylase 578726..580939 Streptococcus pneumoniae Taiwan19F-14 7687318 YP_002742099.1 CDS cysE NC_012469.1 580955 581572 D identified by match to protein family HMM TIGR01172; serine O-acetyltransferase 580955..581572 Streptococcus pneumoniae Taiwan19F-14 7685396 YP_002742100.1 CDS SPT_0619 NC_012469.1 581584 582468 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 581584..582468 Streptococcus pneumoniae Taiwan19F-14 7685363 YP_002742101.1 CDS cysS NC_012469.1 582555 583898 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 582555..583898 Streptococcus pneumoniae Taiwan19F-14 7686819 YP_002742102.1 CDS SPT_0621 NC_012469.1 583891 584277 D identified by match to protein family HMM PF00636; ribonuclease III family protein 583891..584277 Streptococcus pneumoniae Taiwan19F-14 7685372 YP_002742103.1 CDS SPT_0622 NC_012469.1 584281 585165 D leucine-rich protein 584281..585165 Streptococcus pneumoniae Taiwan19F-14 7685235 YP_002742104.1 CDS SPT_0623 NC_012469.1 585213 585329 D identified by glimmer; putative; hypothetical protein 585213..585329 Streptococcus pneumoniae Taiwan19F-14 7685937 YP_002742105.1 CDS SPT_0624 NC_012469.1 585302 585901 D identified by glimmer; putative; hypothetical protein 585302..585901 Streptococcus pneumoniae Taiwan19F-14 7686794 YP_002742106.1 CDS SPT_0625 NC_012469.1 586047 586220 D identified by glimmer; putative; hypothetical protein 586047..586220 Streptococcus pneumoniae Taiwan19F-14 7685278 YP_002742107.1 CDS SPT_0626 NC_012469.1 586571 587848 D identified by match to protein family HMM PF02687; peptide ABC transporter permease 586571..587848 Streptococcus pneumoniae Taiwan19F-14 7685559 YP_002742108.1 CDS SPT_0627 NC_012469.1 587861 588508 D identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 587861..588508 Streptococcus pneumoniae Taiwan19F-14 7685922 YP_002742109.1 CDS SPT_0628 NC_012469.1 588560 589939 D identified by match to protein family HMM PF02687; peptide ABC transporter permease 588560..589939 Streptococcus pneumoniae Taiwan19F-14 7685498 YP_002742110.1 CDS SPT_0629 NC_012469.1 590250 590906 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; VncR, response regulator 590250..590906 Streptococcus pneumoniae Taiwan19F-14 7687316 YP_002742111.1 CDS SPT_0630 NC_012469.1 590903 592231 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; VncS, histidine kinase 590903..592231 Streptococcus pneumoniae Taiwan19F-14 7685369 YP_002742112.1 CDS SPT_0631 NC_012469.1 592372 593253 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 592372..593253 Streptococcus pneumoniae Taiwan19F-14 7686286 YP_002742113.1 CDS SPT_0632 NC_012469.1 593574 594764 R identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF01794; oxidoreductase, NAD-binding complement(593574..594764) Streptococcus pneumoniae Taiwan19F-14 7686499 YP_002742114.1 CDS SPT_0633 NC_012469.1 594908 595567 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease complement(594908..595567) Streptococcus pneumoniae Taiwan19F-14 7686976 YP_002742115.1 CDS SPT_0634 NC_012469.1 595577 596254 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease complement(595577..596254) Streptococcus pneumoniae Taiwan19F-14 7686369 YP_002742116.1 CDS SPT_0635 NC_012469.1 596267 597061 R identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor complement(596267..597061) Streptococcus pneumoniae Taiwan19F-14 7685286 YP_002742117.1 CDS SPT_0636 NC_012469.1 597072 597830 R identified by match to protein family HMM PF00005; ATP-binding protein complement(597072..597830) Streptococcus pneumoniae Taiwan19F-14 7685716 YP_002742118.1 CDS recJ NC_012469.1 598107 600329 D identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 598107..600329 Streptococcus pneumoniae Taiwan19F-14 7685997 YP_002742119.1 CDS SPT_0638 NC_012469.1 600504 602165 D identified by match to protein family HMM PF00753; match to protein family HMM PF07521; metallo-beta-lactamase family protein 600504..602165 Streptococcus pneumoniae Taiwan19F-14 7685816 YP_002742120.1 CDS SPT_0639 NC_012469.1 602234 603013 D identified by match to protein family HMM PF00756; tributyrin esterase 602234..603013 Streptococcus pneumoniae Taiwan19F-14 7686288 YP_002742121.1 CDS SPT_0640 NC_012469.1 603125 604345 D identified by match to protein family HMM PF02388; serine/alanine-adding enzyme MurM 603125..604345 Streptococcus pneumoniae Taiwan19F-14 7686100 YP_002742122.1 CDS SPT_0641 NC_012469.1 604350 605582 D identified by match to protein family HMM PF02388; alanine-adding enzyme MurN 604350..605582 Streptococcus pneumoniae Taiwan19F-14 7685651 YP_002742123.1 CDS SPT_0642 NC_012469.1 605661 606362 D identified by match to protein family HMM PF00413; matrixin family 605661..606362 Streptococcus pneumoniae Taiwan19F-14 7686629 YP_002742124.1 CDS uvrC NC_012469.1 606402 608246 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 606402..608246 Streptococcus pneumoniae Taiwan19F-14 7687072 YP_002742125.1 CDS SPT_0644 NC_012469.1 608278 609069 D hypothetical protein 608278..609069 Streptococcus pneumoniae Taiwan19F-14 7687306 YP_002742126.1 CDS SPT_0645 NC_012469.1 609251 610051 R identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor complement(609251..610051) Streptococcus pneumoniae Taiwan19F-14 7686308 YP_002742127.1 CDS SPT_0646 NC_012469.1 610222 610827 D identified by match to protein family HMM PF00881; oxidoreductase 610222..610827 Streptococcus pneumoniae Taiwan19F-14 7685504 YP_002742128.1 CDS pepV NC_012469.1 610840 612240 D divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 610840..612240 Streptococcus pneumoniae Taiwan19F-14 7686240 YP_002742129.1 CDS SPT_0648 NC_012469.1 612294 612872 D identified by match to protein family HMM PF03167; uracil DNA glycosylase family protein 612294..612872 Streptococcus pneumoniae Taiwan19F-14 7686652 YP_002742130.1 CDS SPT_0649 NC_012469.1 613032 613184 D identified by glimmer; putative; hypothetical protein 613032..613184 Streptococcus pneumoniae Taiwan19F-14 7685622 YP_002742131.1 CDS SPT_0650 NC_012469.1 613200 613319 D identified by glimmer; putative; hypothetical protein 613200..613319 Streptococcus pneumoniae Taiwan19F-14 7686209 YP_002742132.1 CDS SPT_0651 NC_012469.1 613490 614815 D branched-chain amino acid transport system II carrier protein 613490..614815 Streptococcus pneumoniae Taiwan19F-14 7687389 YP_002742133.1 CDS SPT_0652 NC_012469.1 614913 615950 D identified by match to protein family HMM PF05343; peptidase, M42 614913..615950 Streptococcus pneumoniae Taiwan19F-14 7685392 YP_002742134.1 CDS SPT_0653 NC_012469.1 615952 616413 D identified by match to protein family HMM PF01230; HIT family protein 615952..616413 Streptococcus pneumoniae Taiwan19F-14 7686586 YP_002742135.1 CDS SPT_0654 NC_012469.1 616431 617147 D D-alanyl-D-alanine carboxypeptidase 616431..617147 Streptococcus pneumoniae Taiwan19F-14 7685277 YP_002742136.1 CDS SPT_0655 NC_012469.1 617187 617324 R identified by glimmer; putative; hypothetical protein complement(617187..617324) Streptococcus pneumoniae Taiwan19F-14 7686165 YP_002742137.1 CDS rplK NC_012469.1 617456 617881 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 617456..617881 Streptococcus pneumoniae Taiwan19F-14 7686473 YP_002742138.1 CDS rplA NC_012469.1 618089 618778 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 618089..618778 Streptococcus pneumoniae Taiwan19F-14 7686386 YP_002742139.1 CDS SPT_0658 NC_012469.1 619370 619516 R chlorohydrolase complement(619370..619516) Streptococcus pneumoniae Taiwan19F-14 7685556 YP_002742140.1 CDS SPT_0659 NC_012469.1 619674 619892 D hypothetical protein 619674..619892 Streptococcus pneumoniae Taiwan19F-14 7686276 YP_002742141.1 CDS SPT_0660 NC_012469.1 620291 620527 D hypothetical protein 620291..620527 Streptococcus pneumoniae Taiwan19F-14 7685405 YP_002742142.1 CDS SPT_0661 NC_012469.1 620937 621929 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 620937..621929 Streptococcus pneumoniae Taiwan19F-14 7686260 YP_002742143.1 CDS SPT_0662 NC_012469.1 621931 622749 D identified by match to protein family HMM PF06182; membrane protein 621931..622749 Streptococcus pneumoniae Taiwan19F-14 7686162 YP_002742144.1 CDS SPT_0663 NC_012469.1 622751 623536 D identified by match to protein family HMM PF06182; ABC transporter permease 622751..623536 Streptococcus pneumoniae Taiwan19F-14 7686557 YP_002742145.1 CDS SPT_0666 NC_012469.1 624768 631199 D identified by match to protein family HMM PF00082; match to protein family HMM PF00746; match to protein family HMM PF02225; match to protein family HMM PF05922; match to protein family HMM PF06280; match to protein family HMM TIGR01167; serine protease 624768..631199 Streptococcus pneumoniae Taiwan19F-14 7686274 YP_002742146.1 CDS SPT_0667 NC_012469.1 631831 632307 D identified by match to protein family HMM PF00359; phosphotransferase system sugar-specific EII component 631831..632307 Streptococcus pneumoniae Taiwan19F-14 7686600 YP_002742147.1 CDS SPT_0668 NC_012469.1 632345 632650 D PTS system, galactose-specific IIB component 632345..632650 Streptococcus pneumoniae Taiwan19F-14 7685684 YP_002742148.1 CDS SPT_0669 NC_012469.1 632698 634173 D phosphotransferase system sugar-specific EII component 632698..634173 Streptococcus pneumoniae Taiwan19F-14 7686956 YP_002742149.1 CDS SPT_0670 NC_012469.1 634568 641269 D identified by match to protein family HMM PF00703; match to protein family HMM PF00746; match to protein family HMM PF02836; match to protein family HMM PF02837; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM PF07532; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; beta-galactosidase 634568..641269 Streptococcus pneumoniae Taiwan19F-14 7686051 YP_002742150.1 CDS SPT_0671 NC_012469.1 641517 641747 R identified by glimmer; putative; hypothetical protein complement(641517..641747) Streptococcus pneumoniae Taiwan19F-14 7686854 YP_002742151.1 CDS SPT_0672 NC_012469.1 641716 642129 R identified by glimmer; putative; hypothetical protein complement(641716..642129) Streptococcus pneumoniae Taiwan19F-14 7687131 YP_002742152.1 CDS SPT_0673 NC_012469.1 642129 642374 R identified by glimmer; putative; hypothetical protein complement(642129..642374) Streptococcus pneumoniae Taiwan19F-14 7685262 YP_002742153.1 CDS SPT_0674 NC_012469.1 642585 642944 R integral membrane protein complement(642585..642944) Streptococcus pneumoniae Taiwan19F-14 7686769 YP_002742154.1 CDS SPT_0677 NC_012469.1 643977 644534 D identified by match to protein family HMM PF06962; SAM-dependent methyltransferase 643977..644534 Streptococcus pneumoniae Taiwan19F-14 7686995 YP_002742155.1 CDS SPT_0678 NC_012469.1 644527 644781 D hypothetical protein 644527..644781 Streptococcus pneumoniae Taiwan19F-14 7685712 YP_002742156.1 CDS SPT_0679 NC_012469.1 644793 646847 D identified by match to protein family HMM PF00999; sodium/hydrogen exchanger family protein 644793..646847 Streptococcus pneumoniae Taiwan19F-14 7686934 YP_002742157.1 CDS SPT_0680 NC_012469.1 647026 647886 D identified by match to protein family HMM PF03631; ribonuclease BN 647026..647886 Streptococcus pneumoniae Taiwan19F-14 7687106 YP_002742158.1 CDS SPT_0682 NC_012469.1 648097 648807 D identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein 648097..648807 Streptococcus pneumoniae Taiwan19F-14 7686655 YP_002742159.1 CDS SPT_0683 NC_012469.1 648827 649393 D identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein 648827..649393 Streptococcus pneumoniae Taiwan19F-14 7686215 YP_002742160.1 CDS SPT_0684 NC_012469.1 649404 650516 D identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 649404..650516 Streptococcus pneumoniae Taiwan19F-14 7687360 YP_002742161.1 CDS SPT_0685 NC_012469.1 650739 651476 D identified by match to protein family HMM PF00072; match to protein family HMM PF00165; response regulator 650739..651476 Streptococcus pneumoniae Taiwan19F-14 7685959 YP_002742162.1 CDS SPT_0686 NC_012469.1 651473 653164 D identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF02743; match to protein family HMM PF06580; histidine kinase 651473..653164 Streptococcus pneumoniae Taiwan19F-14 7686220 YP_002742163.1 CDS SPT_0687 NC_012469.1 653280 653843 D identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440; hypothetical protein 653280..653843 Streptococcus pneumoniae Taiwan19F-14 7685241 YP_002742164.1 CDS zmpB NC_012469.1 653865 659573 D identified by match to protein family HMM PF00746; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM TIGR01167; zinc metalloprotease ZmpB 653865..659573 Streptococcus pneumoniae Taiwan19F-14 7686335 YP_002742165.1 CDS SPT_0689 NC_012469.1 659634 661355 D identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553; chorismate binding enzyme 659634..661355 Streptococcus pneumoniae Taiwan19F-14 7685694 YP_002742166.1 CDS SPT_0690 NC_012469.1 661356 661973 D hypothetical protein 661356..661973 Streptococcus pneumoniae Taiwan19F-14 7685260 YP_002742167.1 CDS SPT_0691 NC_012469.1 662023 663021 D identified by match to protein family HMM PF01473; match to protein family HMM PF05901; match to protein family HMM PF07553; hypothetical protein 662023..663021 Streptococcus pneumoniae Taiwan19F-14 7687359 YP_002742168.1 CDS SPT_0692 NC_012469.1 663148 664107 D identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744; glucokinase (Glucose kinase) 663148..664107 Streptococcus pneumoniae Taiwan19F-14 7685801 YP_002742169.1 CDS thyA NC_012469.1 664204 665043 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 664204..665043 Streptococcus pneumoniae Taiwan19F-14 7686588 YP_002742170.1 CDS SPT_0694 NC_012469.1 665090 665260 R hypothetical protein complement(665090..665260) Streptococcus pneumoniae Taiwan19F-14 7685654 YP_002742171.1 CDS miaA NC_012469.1 665381 666265 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 665381..666265 Streptococcus pneumoniae Taiwan19F-14 7687000 YP_002742172.1 CDS hflX NC_012469.1 666258 667496 D identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231; match to protein family HMM TIGR03156; GTP-binding proten HflX 666258..667496 Streptococcus pneumoniae Taiwan19F-14 7686508 YP_002742173.1 CDS SPT_0697 NC_012469.1 667489 668112 D cystathionine beta-lyase 667489..668112 Streptococcus pneumoniae Taiwan19F-14 7686251 YP_002742174.1 CDS rnz NC_012469.1 668127 669056 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 668127..669056 Streptococcus pneumoniae Taiwan19F-14 7685963 YP_002742175.1 CDS SPT_0699 NC_012469.1 669077 669832 D identified by match to protein family HMM PF00106; match to protein family HMM PF08659; oxidoreductase 669077..669832 Streptococcus pneumoniae Taiwan19F-14 7686494 YP_002742176.1 CDS SPT_0700 NC_012469.1 669886 670854 R identified by match to protein family HMM PF00126; regulatory function on capsule expression complement(669886..670854) Streptococcus pneumoniae Taiwan19F-14 7685254 YP_002742177.1 CDS SPT_0701 NC_012469.1 670858 671127 D identified by match to protein family HMM PF06014; hypothetical protein 670858..671127 Streptococcus pneumoniae Taiwan19F-14 7685695 YP_002742178.1 CDS SPT_0702 NC_012469.1 671127 671507 D identified by match to protein family HMM PF00581; rhodanese family protein 671127..671507 Streptococcus pneumoniae Taiwan19F-14 7686992 YP_002742179.1 CDS SPT_0703 NC_012469.1 671596 671823 D hypothetical protein 671596..671823 Streptococcus pneumoniae Taiwan19F-14 7686017 YP_002742180.1 CDS SPT_0704 NC_012469.1 671863 672588 R identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal small subunit pseudouridine synthase A, putative complement(671863..672588) Streptococcus pneumoniae Taiwan19F-14 7687054 YP_002742181.1 CDS typA NC_012469.1 672750 674591 D identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA/BipA 672750..674591 Streptococcus pneumoniae Taiwan19F-14 7686905 YP_002742182.1 CDS SPT_0706 NC_012469.1 674611 674865 D hypothetical protein 674611..674865 Streptococcus pneumoniae Taiwan19F-14 7686357 YP_002742183.1 CDS SPT_0707 NC_012469.1 675230 675529 D identified by match to protein family HMM TIGR01653; bacteriocin, lactococcin 972 family 675230..675529 Streptococcus pneumoniae Taiwan19F-14 7686136 YP_002742184.1 CDS SPT_0708 NC_012469.1 675600 677621 D identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 675600..677621 Streptococcus pneumoniae Taiwan19F-14 7685838 YP_002742185.1 CDS SPT_0709 NC_012469.1 677623 678264 D identified by match to protein family HMM PF00005; Na+ ABC transporter ATP-binding protein 677623..678264 Streptococcus pneumoniae Taiwan19F-14 7685321 YP_002742186.1 CDS murD NC_012469.1 678368 679720 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 678368..679720 Streptococcus pneumoniae Taiwan19F-14 7686078 YP_002742187.1 CDS murG NC_012469.1 679722 680780 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 679722..680780 Streptococcus pneumoniae Taiwan19F-14 7687006 YP_002742188.1 CDS SPT_0712 NC_012469.1 680790 682010 D identified by match to protein family HMM PF03799; match to protein family HMM PF08478; cell division protein DivIB 680790..682010 Streptococcus pneumoniae Taiwan19F-14 7687382 YP_002742189.1 CDS pyrF NC_012469.1 682243 682944 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 682243..682944 Streptococcus pneumoniae Taiwan19F-14 7686876 YP_002742190.1 CDS pyrE NC_012469.1 682978 683610 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 682978..683610 Streptococcus pneumoniae Taiwan19F-14 7685283 YP_002742191.1 CDS SPT_0715 NC_012469.1 684071 684193 D identified by glimmer; putative; hypothetical protein 684071..684193 Streptococcus pneumoniae Taiwan19F-14 7686938 YP_002742192.1 CDS SPT_0716 NC_012469.1 684289 685053 D hypothetical protein 684289..685053 Streptococcus pneumoniae Taiwan19F-14 7687177 YP_002742193.1 CDS SPT_0717 NC_012469.1 685002 685535 D identified by glimmer; putative; hypothetical protein 685002..685535 Streptococcus pneumoniae Taiwan19F-14 7685850 YP_002742194.1 CDS SPT_0718 NC_012469.1 685808 686512 D hypothetical protein 685808..686512 Streptococcus pneumoniae Taiwan19F-14 7686190 YP_002742195.1 CDS SPT_0719 NC_012469.1 686509 687156 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 686509..687156 Streptococcus pneumoniae Taiwan19F-14 7685470 YP_002742196.1 CDS SPT_0723 NC_012469.1 688871 689062 R glutamine ABC transporter permease complement(688871..689062) Streptococcus pneumoniae Taiwan19F-14 7685375 YP_002742197.1 CDS SPT_0726 NC_012469.1 690634 691257 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease complement(690634..691257) Streptococcus pneumoniae Taiwan19F-14 7686666 YP_002742198.1 CDS SPT_0727 NC_012469.1 691217 691897 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; glutamine ABC transporter permease complement(691217..691897) Streptococcus pneumoniae Taiwan19F-14 7686990 YP_002742199.1 CDS SPT_0728 NC_012469.1 692112 692258 D hypothetical protein 692112..692258 Streptococcus pneumoniae Taiwan19F-14 7686107 YP_002742200.1 CDS lysS NC_012469.1 692386 693876 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 692386..693876 Streptococcus pneumoniae Taiwan19F-14 7685201 YP_002742201.1 CDS SPT_0730 NC_012469.1 694296 695642 D identified by match to protein family HMM PF01609; Spn1 transposase 694296..695642 Streptococcus pneumoniae Taiwan19F-14 7686704 YP_002742202.1 CDS lctO NC_012469.1 696209 697345 D identified by match to protein family HMM PF01070; match to protein family HMM TIGR02708; L-lactate oxidase 696209..697345 Streptococcus pneumoniae Taiwan19F-14 7687291 YP_002742203.1 CDS SPT_0732 NC_012469.1 697901 698569 D identified by match to protein family HMM PF03070; tena/thi-4 family 697901..698569 Streptococcus pneumoniae Taiwan19F-14 7685818 YP_002742204.1 CDS thiM NC_012469.1 698806 699588 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 698806..699588 Streptococcus pneumoniae Taiwan19F-14 7686535 YP_002742205.1 CDS thiE1 NC_012469.1 699590 700219 D identified by match to protein family HMM PF02581; match to protein family HMM TIGR00693; thiamine-phosphate pyrophosphorylase 699590..700219 Streptococcus pneumoniae Taiwan19F-14 7686789 YP_002742206.1 CDS SPT_0735 NC_012469.1 700778 701338 D cobalt ABC transporter permease 700778..701338 Streptococcus pneumoniae Taiwan19F-14 7686252 YP_002742207.1 CDS SPT_0736 NC_012469.1 701339 702724 D identified by match to protein family HMM PF00005; cobalt ABC transporter ATP-binding protein 701339..702724 Streptococcus pneumoniae Taiwan19F-14 7685540 YP_002742208.1 CDS SPT_0737 NC_012469.1 702726 703376 D hypothetical protein 702726..703376 Streptococcus pneumoniae Taiwan19F-14 7686315 YP_002742209.1 CDS SPT_0738 NC_012469.1 703387 704079 D identified by match to protein family HMM PF03070; tena/thi-4 family 703387..704079 Streptococcus pneumoniae Taiwan19F-14 7685829 YP_002742210.1 CDS thiW NC_012469.1 704084 704608 D identified by match to protein family HMM TIGR02359; ThiW protein 704084..704608 Streptococcus pneumoniae Taiwan19F-14 7686515 YP_002742211.1 CDS SPT_0740 NC_012469.1 704608 705411 D identified by match to protein family HMM PF02110; hydroxyethylthiazole kinase 704608..705411 Streptococcus pneumoniae Taiwan19F-14 7685749 YP_002742212.1 CDS thiE NC_012469.1 705404 706036 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 705404..706036 Streptococcus pneumoniae Taiwan19F-14 7687268 YP_002742213.1 CDS thiD NC_012469.1 706245 707036 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(706245..707036) Streptococcus pneumoniae Taiwan19F-14 7686029 YP_002742214.1 CDS SPT_0743 NC_012469.1 707402 707797 D identified by match to protein family HMM PF03965; match to protein family HMM TIGR02698; copper transport repressor, CopY/TcrY family 707402..707797 Streptococcus pneumoniae Taiwan19F-14 7687004 YP_002742215.1 CDS SPT_0744 NC_012469.1 707808 708179 D hypothetical protein 707808..708179 Streptococcus pneumoniae Taiwan19F-14 7686140 YP_002742216.1 CDS SPT_0745 NC_012469.1 708189 710432 D cation-transporting ATPase PacS 708189..710432 Streptococcus pneumoniae Taiwan19F-14 7686325 YP_002742217.1 CDS spxB NC_012469.1 710639 712414 D identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR02720; pyruvate oxidase 710639..712414 Streptococcus pneumoniae Taiwan19F-14 7687021 YP_002742218.1 CDS SPT_0747 NC_012469.1 712525 712872 D identified by match to protein family HMM PF00903; glyoxalase family protein 712525..712872 Streptococcus pneumoniae Taiwan19F-14 7687397 YP_002742219.1 CDS SPT_0748 NC_012469.1 712989 713642 R transposase family protein complement(712989..713642) Streptococcus pneumoniae Taiwan19F-14 7686168 YP_002742220.1 CDS SPT_0749 NC_012469.1 713530 713796 R transposase complement(713530..713796) Streptococcus pneumoniae Taiwan19F-14 7687065 YP_002742221.1 CDS SPT_0750 NC_012469.1 713793 714035 R identified by glimmer; putative; hypothetical protein complement(713793..714035) Streptococcus pneumoniae Taiwan19F-14 7685294 YP_002742222.1 CDS SPT_0751 NC_012469.1 714100 714396 D 6-phospho-beta-glucosidase AscB 714100..714396 Streptococcus pneumoniae Taiwan19F-14 7686099 YP_002742223.1 CDS manA NC_012469.1 714517 715461 D identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase, class I 714517..715461 Streptococcus pneumoniae Taiwan19F-14 7685790 YP_002742224.1 CDS SPT_0753 NC_012469.1 715482 716813 R identified by match to protein family HMM PF00209; sodium-dependent transporter complement(715482..716813) Streptococcus pneumoniae Taiwan19F-14 7687348 YP_002742225.1 CDS SPT_0756 NC_012469.1 718145 719320 R identified by match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein complement(718145..719320) Streptococcus pneumoniae Taiwan19F-14 7685866 YP_002742226.1 CDS SPT_0757 NC_012469.1 719379 720224 R identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein complement(719379..720224) Streptococcus pneumoniae Taiwan19F-14 7685312 YP_002742227.1 CDS SPT_0758 NC_012469.1 720349 720906 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 720349..720906 Streptococcus pneumoniae Taiwan19F-14 7686285 YP_002742228.1 CDS SPT_0759 NC_012469.1 720925 721392 D identified by match to protein family HMM PF00383; ComE operon protein 2 720925..721392 Streptococcus pneumoniae Taiwan19F-14 7687201 YP_002742229.1 CDS upp NC_012469.1 721460 722110 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 721460..722110 Streptococcus pneumoniae Taiwan19F-14 7686392 YP_002742230.1 CDS clpP NC_012469.1 722284 722874 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 722284..722874 Streptococcus pneumoniae Taiwan19F-14 7686613 YP_002742231.1 CDS SPT_0762 NC_012469.1 722953 723201 D hypothetical protein 722953..723201 Streptococcus pneumoniae Taiwan19F-14 7685764 YP_002742232.1 CDS SPT_0763 NC_012469.1 723303 724463 D identified by match to protein family HMM PF01094; ABC transporter substrate-binding protein - branched chain amino acid transport 723303..724463 Streptococcus pneumoniae Taiwan19F-14 7686144 YP_002742233.1 CDS SPT_0764 NC_012469.1 724731 725600 D identified by match to protein family HMM PF02653; high-affinity branched-chain amino acid transport system permeaseprotein LivH (LIV-I protein H) 724731..725600 Streptococcus pneumoniae Taiwan19F-14 7686833 YP_002742234.1 CDS SPT_0765 NC_012469.1 725604 726560 D identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 725604..726560 Streptococcus pneumoniae Taiwan19F-14 7686571 YP_002742235.1 CDS SPT_0766 NC_012469.1 726560 727324 D identified by match to protein family HMM PF00005; high-affinity branched-chain amino acid transport ATP-binding proteinlivG (LIV-I protein G) 726560..727324 Streptococcus pneumoniae Taiwan19F-14 7687369 YP_002742236.1 CDS SPT_0767 NC_012469.1 727324 728034 D identified by match to protein family HMM PF00005; high-affinity branched-chain amino acid transport ATP-binding proteinlivF (LIV-I protein F) 727324..728034 Streptococcus pneumoniae Taiwan19F-14 7685332 YP_002742237.1 CDS SPT_0768 NC_012469.1 728448 729104 D identified by match to protein family HMM PF00571; AcuB family protein 728448..729104 Streptococcus pneumoniae Taiwan19F-14 7685674 YP_002742238.1 CDS prfB NC_012469.1 729318 730307 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 729318..730307 Streptococcus pneumoniae Taiwan19F-14 7686440 YP_002742239.1 CDS ftsE NC_012469.1 730325 731017 D identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673; cell division ATP-binding protein FtsE 730325..731017 Streptococcus pneumoniae Taiwan19F-14 7686591 YP_002742240.1 CDS SPT_0771 NC_012469.1 731010 731936 D cell division ABC transporter, permease protein FtsX 731010..731936 Streptococcus pneumoniae Taiwan19F-14 7685683 YP_002742241.1 CDS SPT_0772 NC_012469.1 732222 734402 D identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02003; pts system, iibc component 732222..734402 Streptococcus pneumoniae Taiwan19F-14 7687038 YP_002742242.1 CDS SPT_0773 NC_012469.1 734454 735269 D identified by match to protein family HMM PF03372; metal-dependent hydrolase 734454..735269 Streptococcus pneumoniae Taiwan19F-14 7686006 YP_002742243.1 CDS SPT_0774 NC_012469.1 735409 736752 D identified by match to protein family HMM PF00270; match to protein family HMM PF00271; superfamily II DNA and RNA helicase 735409..736752 Streptococcus pneumoniae Taiwan19F-14 7686161 YP_002742244.1 CDS metK NC_012469.1 737129 738319 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 737129..738319 Streptococcus pneumoniae Taiwan19F-14 7686243 YP_002742245.1 CDS SPT_0776 NC_012469.1 738409 738573 R hypothetical protein complement(738409..738573) Streptococcus pneumoniae Taiwan19F-14 7686634 YP_002742246.1 CDS SPT_0777 NC_012469.1 738872 739807 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 738872..739807 Streptococcus pneumoniae Taiwan19F-14 7686324 YP_002742247.1 CDS holA NC_012469.1 739841 740878 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 739841..740878 Streptococcus pneumoniae Taiwan19F-14 7687394 YP_002742248.1 CDS SPT_0779 NC_012469.1 741051 741656 D identified by match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase [Mn] (General stress protein 24)(GSP24) 741051..741656 Streptococcus pneumoniae Taiwan19F-14 7686877 YP_002742249.1 CDS SPT_0780 NC_012469.1 741813 742343 D identified by match to protein family HMM PF06265; transcriptional regulator 741813..742343 Streptococcus pneumoniae Taiwan19F-14 7686154 YP_002742250.1 CDS SPT_0781 NC_012469.1 742364 743266 D identified by match to protein family HMM TIGR00048; radical SAM enzyme, Cfr family 742364..743266 Streptococcus pneumoniae Taiwan19F-14 7685919 YP_002742251.1 CDS SPT_0782 NC_012469.1 743266 743748 D identified by match to protein family HMM PF04892; VanZ family protein 743266..743748 Streptococcus pneumoniae Taiwan19F-14 7685271 YP_002742252.1 CDS SPT_0783 NC_012469.1 743750 745291 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 743750..745291 Streptococcus pneumoniae Taiwan19F-14 7686150 YP_002742253.1 CDS SPT_0784 NC_012469.1 745347 746150 R identified by match to protein family HMM PF00160; peptidyl-prolyl cis-trans isomerase, cyclophilin-type complement(745347..746150) Streptococcus pneumoniae Taiwan19F-14 7687158 YP_002742254.1 CDS SPT_0785 NC_012469.1 746234 746446 R hypothetical protein complement(746234..746446) Streptococcus pneumoniae Taiwan19F-14 7685469 YP_002742255.1 CDS SPT_0786 NC_012469.1 746925 747125 R identified by glimmer; putative; hypothetical protein complement(746925..747125) Streptococcus pneumoniae Taiwan19F-14 7686086 YP_002742256.1 CDS rpsP NC_012469.1 747304 747576 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 747304..747576 Streptococcus pneumoniae Taiwan19F-14 7686965 YP_002742257.1 CDS SPT_0788 NC_012469.1 747596 747835 D hypothetical protein 747596..747835 Streptococcus pneumoniae Taiwan19F-14 7687200 YP_002742258.1 CDS SPT_0789 NC_012469.1 748227 749573 R identified by match to protein family HMM PF01609; Spn1 transposase complement(748227..749573) Streptococcus pneumoniae Taiwan19F-14 7686264 YP_002742259.1 CDS SPT_0792 NC_012469.1 749858 750208 D transposase family protein 749858..750208 Streptococcus pneumoniae Taiwan19F-14 7687233 YP_002742260.1 CDS SPT_0795 NC_012469.1 752031 753008 R identified by match to protein family HMM PF01118; match to protein family HMM PF01408; oxidoreductase complement(752031..753008) Streptococcus pneumoniae Taiwan19F-14 7686430 YP_002742261.1 CDS SPT_0796 NC_012469.1 753223 753600 D hypothetical protein 753223..753600 Streptococcus pneumoniae Taiwan19F-14 7685943 YP_002742262.1 CDS SPT_0797 NC_012469.1 753784 755226 D identified by match to protein family HMM PF01522; peptidoglycan GlcNAc deacetylase 753784..755226 Streptococcus pneumoniae Taiwan19F-14 7686623 YP_002742263.1 CDS SPT_0798 NC_012469.1 755340 756182 D identified by match to protein family HMM PF00248; 2,5-diketo-d-gluconic acid reductase a (2,5-dkgreductase a) (2,5-dkgr a) (25dkgr-a) (akr5c) 755340..756182 Streptococcus pneumoniae Taiwan19F-14 7685679 YP_002742264.1 CDS SPT_0799 NC_012469.1 756455 757216 D hypothetical protein 756455..757216 Streptococcus pneumoniae Taiwan19F-14 7687039 YP_002742265.1 CDS glyQ NC_012469.1 757409 758326 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 757409..758326 Streptococcus pneumoniae Taiwan19F-14 7686246 YP_002742266.1 CDS glyS NC_012469.1 758586 760622 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 758586..760622 Streptococcus pneumoniae Taiwan19F-14 7686174 YP_002742267.1 CDS SPT_0802 NC_012469.1 760664 760921 D identified by match to protein family HMM PF05979; hypothetical protein 760664..760921 Streptococcus pneumoniae Taiwan19F-14 7686458 YP_002742268.1 CDS SPT_0803 NC_012469.1 761038 762282 R identified by match to protein family HMM PF03358; NADPH-dependent fmn reductase domain protein complement(761038..762282) Streptococcus pneumoniae Taiwan19F-14 7686406 YP_002742269.1 CDS SPT_0804 NC_012469.1 762301 762906 R NADPH-dependent fmn reductase domain protein complement(762301..762906) Streptococcus pneumoniae Taiwan19F-14 7686506 YP_002742270.1 CDS SPT_0805 NC_012469.1 762966 763889 R identified by match to protein family HMM PF02424; thiamine biosynthesis lipoprotein complement(762966..763889) Streptococcus pneumoniae Taiwan19F-14 7685698 YP_002742271.1 CDS SPT_0806 NC_012469.1 764183 765562 D identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; NADH oxidase (noxase) 764183..765562 Streptococcus pneumoniae Taiwan19F-14 7686061 YP_002742272.1 CDS SPT_0807 NC_012469.1 765714 766589 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 765714..766589 Streptococcus pneumoniae Taiwan19F-14 7687069 YP_002742273.1 CDS SPT_0808 NC_012469.1 766590 767171 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 766590..767171 Streptococcus pneumoniae Taiwan19F-14 7686460 YP_002742274.1 CDS SPT_0809 NC_012469.1 767192 767839 R identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin-3 (Hemolysin III) (Hly-III) complement(767192..767839) Streptococcus pneumoniae Taiwan19F-14 7687167 YP_002742275.1 CDS SPT_0810 NC_012469.1 767836 768282 R identified by match to protein family HMM PF08876; hypothetical protein complement(767836..768282) Streptococcus pneumoniae Taiwan19F-14 7686233 YP_002742276.1 CDS SPT_0811 NC_012469.1 768417 768911 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 768417..768911 Streptococcus pneumoniae Taiwan19F-14 7686113 YP_002742277.1 CDS SPT_0812 NC_012469.1 768911 769441 D O6-methylguanine-DNA methyltransferase 768911..769441 Streptococcus pneumoniae Taiwan19F-14 7687074 YP_002742278.1 CDS SPT_0813 NC_012469.1 769435 769791 D identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; arsenate reductase 769435..769791 Streptococcus pneumoniae Taiwan19F-14 7685244 YP_002742279.1 CDS SPT_0814 NC_012469.1 769949 770749 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; aspartate/glutamate ABC transporter permease 769949..770749 Streptococcus pneumoniae Taiwan19F-14 7686944 YP_002742280.1 CDS SPT_0815 NC_012469.1 770749 771492 D identified by match to protein family HMM PF00005; L-cystine import ATP-binding protein TcyN 770749..771492 Streptococcus pneumoniae Taiwan19F-14 7687077 YP_002742281.1 CDS SPT_0816 NC_012469.1 771570 771794 D hypothetical protein 771570..771794 Streptococcus pneumoniae Taiwan19F-14 7686649 YP_002742282.1 CDS trxB NC_012469.1 771860 772771 D identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01292; thioredoxin-disulfide reductase 771860..772771 Streptococcus pneumoniae Taiwan19F-14 7685675 YP_002742283.1 CDS SPT_0818 NC_012469.1 772809 773537 R identified by match to protein family HMM PF00588; match to protein family HMM PF08032; match to protein family HMM TIGR00186; RNA methyltransferase, TrmH family, group 3 complement(772809..773537) Streptococcus pneumoniae Taiwan19F-14 7686170 YP_002742284.1 CDS def NC_012469.1 773582 774193 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(773582..774193) Streptococcus pneumoniae Taiwan19F-14 7686098 YP_002742285.1 CDS SPT_0820 NC_012469.1 774517 774630 R hypothetical protein complement(774517..774630) Streptococcus pneumoniae Taiwan19F-14 7686352 YP_002742286.1 CDS SPT_0823 NC_012469.1 775780 776607 D identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein 775780..776607 Streptococcus pneumoniae Taiwan19F-14 7686903 YP_002742287.1 CDS SPT_0824 NC_012469.1 776609 777244 D identified by match to protein family HMM PF00657; hypothetical protein 776609..777244 Streptococcus pneumoniae Taiwan19F-14 7687232 YP_002742288.1 CDS SPT_0825 NC_012469.1 777328 778053 D CppA protein 777328..778053 Streptococcus pneumoniae Taiwan19F-14 7686396 YP_002742289.1 CDS SPT_0826 NC_012469.1 778050 778985 D identified by match to protein family HMM PF00144; beta-lactamase 778050..778985 Streptococcus pneumoniae Taiwan19F-14 7686178 YP_002742290.1 CDS SPT_0827 NC_012469.1 778994 779890 D identified by match to protein family HMM PF00892; membrane protein 778994..779890 Streptococcus pneumoniae Taiwan19F-14 7685329 YP_002742291.1 CDS SPT_0828 NC_012469.1 779933 780631 R identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator complement(779933..780631) Streptococcus pneumoniae Taiwan19F-14 7686389 YP_002742292.1 CDS guaA NC_012469.1 780773 782335 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 780773..782335 Streptococcus pneumoniae Taiwan19F-14 7685432 YP_002742293.1 CDS SPT_0833 NC_012469.1 784177 784323 D hypothetical protein 784177..784323 Streptococcus pneumoniae Taiwan19F-14 7686284 YP_002742294.1 CDS SPT_0834 NC_012469.1 784445 785437 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(784445..785437) Streptococcus pneumoniae Taiwan19F-14 7685435 YP_002742295.1 CDS SPT_0835 NC_012469.1 785597 787351 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein/permease 785597..787351 Streptococcus pneumoniae Taiwan19F-14 7685660 YP_002742296.1 CDS SPT_0836 NC_012469.1 787335 789056 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 787335..789056 Streptococcus pneumoniae Taiwan19F-14 7685717 YP_002742297.1 CDS SPT_0837 NC_012469.1 789067 789651 D identified by match to protein family HMM TIGR02185; hypothetical protein 789067..789651 Streptococcus pneumoniae Taiwan19F-14 7687353 YP_002742298.1 CDS SPT_0838 NC_012469.1 789651 790346 D hypothetical protein 789651..790346 Streptococcus pneumoniae Taiwan19F-14 7685245 YP_002742299.1 CDS SPT_0839 NC_012469.1 790334 791698 D identified by match to protein family HMM PF00005; cobalt ABC transporter, ATPase component, CbiO 790334..791698 Streptococcus pneumoniae Taiwan19F-14 7685944 YP_002742300.1 CDS SPT_0843 NC_012469.1 792986 794176 R identified by match to protein family HMM PF01555; DNA modification methyltransferase M.XbaI complement(792986..794176) Streptococcus pneumoniae Taiwan19F-14 7686015 YP_002742301.1 CDS SPT_0846 NC_012469.1 795354 796640 D identified by match to protein family HMM PF01136; peptidase, U32 family protein 795354..796640 Streptococcus pneumoniae Taiwan19F-14 7686752 YP_002742302.1 CDS SPT_0847 NC_012469.1 796895 797044 R hypothetical protein complement(796895..797044) Streptococcus pneumoniae Taiwan19F-14 7685645 YP_002742303.1 CDS SPT_0848 NC_012469.1 797229 797954 D identified by match to protein family HMM PF01136; peptidase, U32 family 797229..797954 Streptococcus pneumoniae Taiwan19F-14 7687005 YP_002742304.1 CDS SPT_0849 NC_012469.1 798459 799181 D identified by match to protein family HMM PF00005; multidrug ABC transporter ATP-binding protein 798459..799181 Streptococcus pneumoniae Taiwan19F-14 7686345 YP_002742305.1 CDS SPT_0850 NC_012469.1 799197 799925 D hypothetical protein 799197..799925 Streptococcus pneumoniae Taiwan19F-14 7686671 YP_002742306.1 CDS SPT_0851 NC_012469.1 800311 800520 D identified by match to protein family HMM PF01381; hypothetical protein 800311..800520 Streptococcus pneumoniae Taiwan19F-14 7686172 YP_002742307.1 CDS SPT_0852 NC_012469.1 800510 800998 D identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM PF03328; match to protein family HMM TIGR01064; hypothetical protein 800510..800998 Streptococcus pneumoniae Taiwan19F-14 7685920 YP_002742308.1 CDS pncB NC_012469.1 801114 802574 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 801114..802574 Streptococcus pneumoniae Taiwan19F-14 7686755 YP_002742309.1 CDS nadE NC_012469.1 802571 803395 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 802571..803395 Streptococcus pneumoniae Taiwan19F-14 7686065 YP_002742310.1 CDS SPT_0855 NC_012469.1 803745 804296 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 803745..804296 Streptococcus pneumoniae Taiwan19F-14 7686844 YP_002742311.1 CDS SPT_0856 NC_012469.1 805758 806147 D identified by match to protein family HMM PF01473; choline binding protein 805758..806147 Streptococcus pneumoniae Taiwan19F-14 7686423 YP_002742312.1 CDS SPT_0857 NC_012469.1 806371 807717 D identified by match to protein family HMM PF01609; Spn1 transposase 806371..807717 Streptococcus pneumoniae Taiwan19F-14 7685874 YP_002742313.1 CDS queA NC_012469.1 808516 809544 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(808516..809544) Streptococcus pneumoniae Taiwan19F-14 7685936 YP_002742314.1 CDS SPT_0859 NC_012469.1 809695 810402 D identified by match to protein family HMM PF01182; glucosamine-6-phosphate deaminase (glucosamine-6-phosphate isomerase) (gnpda) (glcn6p deaminase) 809695..810402 Streptococcus pneumoniae Taiwan19F-14 7685472 YP_002742315.1 CDS rpsU NC_012469.1 810542 810718 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 810542..810718 Streptococcus pneumoniae Taiwan19F-14 7686278 YP_002742316.1 CDS hprK NC_012469.1 810848 811783 D catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 810848..811783 Streptococcus pneumoniae Taiwan19F-14 7687231 YP_002742317.1 CDS lgt NC_012469.1 811776 812564 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 811776..812564 Streptococcus pneumoniae Taiwan19F-14 7685539 YP_002742318.1 CDS SPT_0863 NC_012469.1 812565 812948 D identified by match to protein family HMM PF06103; hypothetical protein 812565..812948 Streptococcus pneumoniae Taiwan19F-14 7686350 YP_002742319.1 CDS SPT_0864 NC_012469.1 812964 813353 D hypothetical protein 812964..813353 Streptococcus pneumoniae Taiwan19F-14 7686326 YP_002742320.1 CDS SPT_0865 NC_012469.1 813437 814567 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 813437..814567 Streptococcus pneumoniae Taiwan19F-14 7685284 YP_002742321.1 CDS SPT_0866 NC_012469.1 814572 815309 D identified by match to protein family HMM PF01643; acyl-ACP thioesterase 814572..815309 Streptococcus pneumoniae Taiwan19F-14 7686221 YP_002742322.1 CDS SPT_0867 NC_012469.1 815320 816093 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460; HAD-superfamily subfamily IIA hydrolase 815320..816093 Streptococcus pneumoniae Taiwan19F-14 7686632 YP_002742323.1 CDS SPT_0868 NC_012469.1 816083 816700 D identified by match to protein family HMM PF07314; match to protein family HMM TIGR01906; integral membrane protein 816083..816700 Streptococcus pneumoniae Taiwan19F-14 7686741 YP_002742324.1 CDS spxA NC_012469.1 816910 817311 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 816910..817311 Streptococcus pneumoniae Taiwan19F-14 7686521 YP_002742325.1 CDS SPT_0870 NC_012469.1 817311 817589 D identified by match to protein family HMM PF05256; hypothetical protein 817311..817589 Streptococcus pneumoniae Taiwan19F-14 7685379 YP_002742326.1 CDS SPT_0871 NC_012469.1 817579 818352 D identified by match to protein family HMM PF00459; inositol monophosphatase family protein 817579..818352 Streptococcus pneumoniae Taiwan19F-14 7685632 YP_002742327.1 CDS SPT_0872 NC_012469.1 818353 819657 D identified by match to protein family HMM PF01189; NOL1/NOP2/sun family protein 818353..819657 Streptococcus pneumoniae Taiwan19F-14 7686081 YP_002742328.1 CDS SPT_0873 NC_012469.1 819888 820001 R hypothetical protein complement(819888..820001) Streptococcus pneumoniae Taiwan19F-14 7686978 YP_002742329.1 CDS SPT_0874 NC_012469.1 820231 821109 D identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate-binding protein PstS 1 (PBP 1) 820231..821109 Streptococcus pneumoniae Taiwan19F-14 7685796 YP_002742330.1 CDS pstC1 NC_012469.1 821109 822026 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 821109..822026 Streptococcus pneumoniae Taiwan19F-14 7687363 YP_002742331.1 CDS pstA1 NC_012469.1 822016 822900 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 822016..822900 Streptococcus pneumoniae Taiwan19F-14 7686733 YP_002742332.1 CDS pstB1 NC_012469.1 822911 823714 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 822911..823714 Streptococcus pneumoniae Taiwan19F-14 7685613 YP_002742333.1 CDS pstB2 NC_012469.1 823727 824485 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 823727..824485 Streptococcus pneumoniae Taiwan19F-14 7685307 YP_002742334.1 CDS phoU1 NC_012469.1 824497 825150 D identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 824497..825150 Streptococcus pneumoniae Taiwan19F-14 7687219 YP_002742335.1 CDS SPT_0880 NC_012469.1 825307 826122 D identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine-binding protein 825307..826122 Streptococcus pneumoniae Taiwan19F-14 7685657 YP_002742336.1 CDS SPT_0881 NC_012469.1 826142 827413 R identified by match to protein family HMM PF00392; GntR family transcriptional regulator complement(826142..827413) Streptococcus pneumoniae Taiwan19F-14 7686596 YP_002742337.1 CDS SPT_0882 NC_012469.1 827555 828286 D identified by match to protein family HMM PF03306; match to protein family HMM TIGR01252; alpha-acetolactate decarboxylase 827555..828286 Streptococcus pneumoniae Taiwan19F-14 7686159 YP_002742338.1 CDS SPT_0884 NC_012469.1 828296 829048 D hypothetical protein 828296..829048 Streptococcus pneumoniae Taiwan19F-14 7686428 YP_002742339.1 CDS murB NC_012469.1 829160 830110 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 829160..830110 Streptococcus pneumoniae Taiwan19F-14 7687334 YP_002742340.1 CDS SPT_0886 NC_012469.1 830169 831326 D identified by match to protein family HMM PF00005; match to protein family HMM PF08402; spermidine/putrescine import ATP-binding protein PotA 830169..831326 Streptococcus pneumoniae Taiwan19F-14 7687138 YP_002742341.1 CDS SPT_0887 NC_012469.1 831307 832113 D identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 831307..832113 Streptococcus pneumoniae Taiwan19F-14 7686943 YP_002742342.1 CDS SPT_0888 NC_012469.1 832110 832883 D identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 832110..832883 Streptococcus pneumoniae Taiwan19F-14 7685404 YP_002742343.1 CDS SPT_0889 NC_012469.1 832880 833950 D identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein - spermidine/putrescine transport 832880..833950 Streptococcus pneumoniae Taiwan19F-14 7685265 YP_002742344.1 CDS SPT_0890 NC_012469.1 834709 835194 D identified by match to protein family HMM PF04525; hypothetical protein 834709..835194 Streptococcus pneumoniae Taiwan19F-14 7685310 YP_002742345.1 CDS alaS NC_012469.1 835216 837834 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 835216..837834 Streptococcus pneumoniae Taiwan19F-14 7686141 YP_002742346.1 CDS SPT_0892 NC_012469.1 837924 839378 R converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase complement(837924..839378) Streptococcus pneumoniae Taiwan19F-14 7686694 YP_002742347.1 CDS SPT_0893 NC_012469.1 839557 840306 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 839557..840306 Streptococcus pneumoniae Taiwan19F-14 7687295 YP_002742348.1 CDS SPT_0894 NC_012469.1 840287 841921 D hypothetical protein 840287..841921 Streptococcus pneumoniae Taiwan19F-14 7686909 YP_002742349.1 CDS SPT_0895 NC_012469.1 842606 843769 D methyltransferase 842606..843769 Streptococcus pneumoniae Taiwan19F-14 7686042 YP_002742350.1 CDS aroD NC_012469.1 843766 844443 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 843766..844443 Streptococcus pneumoniae Taiwan19F-14 7686889 YP_002742351.1 CDS aroE NC_012469.1 844433 845287 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 844433..845287 Streptococcus pneumoniae Taiwan19F-14 7687115 YP_002742352.1 CDS aroB NC_012469.1 845306 846373 D catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 845306..846373 Streptococcus pneumoniae Taiwan19F-14 7685867 YP_002742353.1 CDS aroC NC_012469.1 846383 847549 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 846383..847549 Streptococcus pneumoniae Taiwan19F-14 7686138 YP_002742354.1 CDS SPT_0900 NC_012469.1 847559 848662 D catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 847559..848662 Streptococcus pneumoniae Taiwan19F-14 7685255 YP_002742355.1 CDS SPT_0901 NC_012469.1 848673 849011 D identified by match to protein family HMM PF06133; hypothetical protein 848673..849011 Streptococcus pneumoniae Taiwan19F-14 7687171 YP_002742356.1 CDS aroA NC_012469.1 849103 850386 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 849103..850386 Streptococcus pneumoniae Taiwan19F-14 7685626 YP_002742357.1 CDS aroK NC_012469.1 850379 850855 D identified by match to protein family HMM PF01202; shikimate kinase 850379..850855 Streptococcus pneumoniae Taiwan19F-14 7685387 YP_002742358.1 CDS SPT_0904 NC_012469.1 850852 851700 D catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 850852..851700 Streptococcus pneumoniae Taiwan19F-14 7687110 YP_002742359.1 CDS SPT_0905 NC_012469.1 851697 852971 D identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator, LytR family 851697..852971 Streptococcus pneumoniae Taiwan19F-14 7686839 YP_002742360.1 CDS SPT_0906 NC_012469.1 853250 854095 D identified by match to protein family HMM PF04991; LicD1 protein 853250..854095 Streptococcus pneumoniae Taiwan19F-14 7685681 YP_002742361.1 CDS SPT_0907 NC_012469.1 854085 855188 D identified by match to protein family HMM PF00534; glycosyl transferase, group 1 854085..855188 Streptococcus pneumoniae Taiwan19F-14 7685771 YP_002742362.1 CDS SPT_0908 NC_012469.1 855190 856176 D identified by match to protein family HMM PF00535; glycosyl transferase, family 2 855190..856176 Streptococcus pneumoniae Taiwan19F-14 7686919 YP_002742363.1 CDS SPT_0909 NC_012469.1 856192 857625 D hypothetical protein 856192..857625 Streptococcus pneumoniae Taiwan19F-14 7685208 YP_002742364.1 CDS SPT_0910 NC_012469.1 857654 858688 D hypothetical protein 857654..858688 Streptococcus pneumoniae Taiwan19F-14 7685984 YP_002742365.1 CDS SPT_0911 NC_012469.1 858888 859625 D enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 858888..859625 Streptococcus pneumoniae Taiwan19F-14 7685860 YP_002742366.1 CDS thrB NC_012469.1 861065 861934 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 861065..861934 Streptococcus pneumoniae Taiwan19F-14 7686644 YP_002742367.1 CDS SPT_0915 NC_012469.1 861950 862246 D hypothetical protein 861950..862246 Streptococcus pneumoniae Taiwan19F-14 7685898 YP_002742368.1 CDS SPT_0916 NC_012469.1 862275 863213 D identified by match to protein family HMM PF01625; match to protein family HMM PF01641; match to protein family HMM TIGR00357; match to protein family HMM TIGR00401; peptide methionine sulfoxide reductase MsrA/msrB 862275..863213 Streptococcus pneumoniae Taiwan19F-14 7687337 YP_002742369.1 CDS SPT_0917 NC_012469.1 863271 864995 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 863271..864995 Streptococcus pneumoniae Taiwan19F-14 7687175 YP_002742370.1 CDS SPT_0918 NC_012469.1 864997 866745 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 864997..866745 Streptococcus pneumoniae Taiwan19F-14 7686448 YP_002742371.1 CDS SPT_0919 NC_012469.1 867002 868261 D identified by match to protein family HMM PF01979; match to protein family HMM PF07969; chlorohydrolase 867002..868261 Streptococcus pneumoniae Taiwan19F-14 7686920 YP_002742372.1 CDS rplJ NC_012469.1 868511 869011 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 868511..869011 Streptococcus pneumoniae Taiwan19F-14 7685259 YP_002742373.1 CDS rplL NC_012469.1 869087 869455 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 869087..869455 Streptococcus pneumoniae Taiwan19F-14 7686945 YP_002742374.1 CDS SPT_0922 NC_012469.1 869702 873280 D identified by glimmer; putative; hypothetical protein 869702..873280 Streptococcus pneumoniae Taiwan19F-14 7686094 YP_002742375.1 CDS SPT_0923 NC_012469.1 873569 874915 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(873569..874915) Streptococcus pneumoniae Taiwan19F-14 7687351 YP_002742376.1 CDS SPT_0924 NC_012469.1 875752 875937 D identified by glimmer; putative; hypothetical protein 875752..875937 Streptococcus pneumoniae Taiwan19F-14 7686023 YP_002742377.1 CDS SPT_0925 NC_012469.1 875969 876478 D transposase family protein 875969..876478 Streptococcus pneumoniae Taiwan19F-14 7685913 YP_002742378.1 CDS SPT_0926 NC_012469.1 876475 876693 D high-affinity Fe2+/Pb2+ permease 876475..876693 Streptococcus pneumoniae Taiwan19F-14 7687325 YP_002742379.1 CDS rpmE2 NC_012469.1 876751 876993 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B complement(876751..876993) Streptococcus pneumoniae Taiwan19F-14 7687082 YP_002742380.1 CDS SPT_0928 NC_012469.1 877089 878024 R identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein complement(877089..878024) Streptococcus pneumoniae Taiwan19F-14 7687017 YP_002742381.1 CDS SPT_0929 NC_012469.1 878128 878571 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 878128..878571 Streptococcus pneumoniae Taiwan19F-14 7687263 YP_002742382.1 CDS SPT_0930 NC_012469.1 878687 878953 D identified by match to protein family HMM PF01817; match to protein family HMM TIGR01805; hypothetical protein 878687..878953 Streptococcus pneumoniae Taiwan19F-14 7686927 YP_002742383.1 CDS SPT_0931 NC_012469.1 878950 879324 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 878950..879324 Streptococcus pneumoniae Taiwan19F-14 7686034 YP_002742384.1 CDS SPT_0932 NC_012469.1 879318 879647 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 879318..879647 Streptococcus pneumoniae Taiwan19F-14 7686922 YP_002742385.1 CDS rplS NC_012469.1 879766 880113 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 879766..880113 Streptococcus pneumoniae Taiwan19F-14 7687213 YP_002742386.1 CDS SPT_0935 NC_012469.1 880398 881396 R identified by match to protein family HMM PF02037; SAP domain protein complement(880398..881396) Streptococcus pneumoniae Taiwan19F-14 7686580 YP_002742387.1 CDS SPT_0936 NC_012469.1 881439 882245 R identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; phosphatase YidA complement(881439..882245) Streptococcus pneumoniae Taiwan19F-14 7685242 YP_002742388.1 CDS SPT_0937 NC_012469.1 882258 883562 R identified by match to protein family HMM PF01966; HD superfamily phosphohydrolase complement(882258..883562) Streptococcus pneumoniae Taiwan19F-14 7686892 YP_002742389.1 CDS SPT_0938 NC_012469.1 883634 884011 D identified by match to protein family HMM PF09148; hypothetical protein 883634..884011 Streptococcus pneumoniae Taiwan19F-14 7685993 YP_002742390.1 CDS SPT_0939 NC_012469.1 884102 884434 D identified by match to protein family HMM PF04297; match to protein family HMM PF04967; match to protein family HMM PF08281; putative DNA-binding protein 884102..884434 Streptococcus pneumoniae Taiwan19F-14 7685360 YP_002742391.1 CDS ffh NC_012469.1 884446 886017 D identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 884446..886017 Streptococcus pneumoniae Taiwan19F-14 7686382 YP_002742392.1 CDS SPT_0941 NC_012469.1 886212 887495 R identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease (Uracil transporter) complement(886212..887495) Streptococcus pneumoniae Taiwan19F-14 7685424 YP_002742393.1 CDS gidB NC_012469.1 887749 888462 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(887749..888462) Streptococcus pneumoniae Taiwan19F-14 7685438 YP_002742394.1 CDS SPT_0943 NC_012469.1 888556 889116 D identified by match to protein family HMM PF04011; cytoplasmic membrane protein 888556..889116 Streptococcus pneumoniae Taiwan19F-14 7685877 YP_002742395.1 CDS SPT_0944 NC_012469.1 889118 890017 D putative metalloprotease; heat shock protein HtpX 889118..890017 Streptococcus pneumoniae Taiwan19F-14 7685948 YP_002742396.1 CDS SPT_0945 NC_012469.1 890061 891587 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(890061..891587) Streptococcus pneumoniae Taiwan19F-14 7687060 YP_002742397.1 CDS SPT_0946 NC_012469.1 892036 892224 R identified by glimmer; putative; hypothetical protein complement(892036..892224) Streptococcus pneumoniae Taiwan19F-14 7685214 YP_002742398.1 CDS SPT_0947 NC_012469.1 892346 892888 D identified by match to protein family HMM PF02620; hypothetical protein 892346..892888 Streptococcus pneumoniae Taiwan19F-14 7686711 YP_002742399.1 CDS nth NC_012469.1 892888 893517 D identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 892888..893517 Streptococcus pneumoniae Taiwan19F-14 7685707 YP_002742400.1 CDS SPT_0949 NC_012469.1 893728 894249 D regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 893728..894249 Streptococcus pneumoniae Taiwan19F-14 7685521 YP_002742401.1 CDS pyrB NC_012469.1 894268 895191 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 894268..895191 Streptococcus pneumoniae Taiwan19F-14 7685431 YP_002742402.1 CDS carA NC_012469.1 895241 896320 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 895241..896320 Streptococcus pneumoniae Taiwan19F-14 7686433 YP_002742403.1 CDS carB NC_012469.1 896633 899809 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 896633..899809 Streptococcus pneumoniae Taiwan19F-14 7686673 YP_002742404.1 CDS SPT_0953 NC_012469.1 900084 900893 R identified by match to protein family HMM PF04991; LicD Protein complement(900084..900893) Streptococcus pneumoniae Taiwan19F-14 7686801 YP_002742405.1 CDS SPT_0954 NC_012469.1 900895 901698 R required for phosphorylcholine incorporation in teichoic and lipoteichoic acids; identified by match to protein family HMM PF04991; phosphotransferase complement(900895..901698) Streptococcus pneumoniae Taiwan19F-14 7687045 YP_002742406.1 CDS SPT_0956 NC_012469.1 901708 903195 R identified by match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide biosynthesis protein complement(901708..903195) Streptococcus pneumoniae Taiwan19F-14 7687114 YP_002742407.1 CDS ispD NC_012469.1 903531 904238 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 903531..904238 Streptococcus pneumoniae Taiwan19F-14 7685828 YP_002742408.1 CDS SPT_0958 NC_012469.1 904243 905265 D identified by match to protein family HMM PF08240; xylitol dehydrogenase 904243..905265 Streptococcus pneumoniae Taiwan19F-14 7687265 YP_002742409.1 CDS SPT_0959 NC_012469.1 905282 906151 D identified by match to protein family HMM PF01633; match to protein family HMM PF01636; choline kinase 905282..906151 Streptococcus pneumoniae Taiwan19F-14 7685767 YP_002742410.1 CDS SPT_0960 NC_012469.1 906141 907019 D identified by match to protein family HMM PF00892; LPS epitope expression regulatory protein 906141..907019 Streptococcus pneumoniae Taiwan19F-14 7686379 YP_002742411.1 CDS SPT_0961 NC_012469.1 907031 907720 D identified by match to protein family HMM PF00483; LPS epitope expression regulatory protein 907031..907720 Streptococcus pneumoniae Taiwan19F-14 7685411 YP_002742412.1 CDS dprA NC_012469.1 907816 908664 D identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA protecting protein DprA 907816..908664 Streptococcus pneumoniae Taiwan19F-14 7686261 YP_002742413.1 CDS SPT_0963 NC_012469.1 908847 908969 R chlorohydrolase complement(908847..908969) Streptococcus pneumoniae Taiwan19F-14 7687342 YP_002742414.1 CDS SPT_0964 NC_012469.1 909546 910589 D identified by match to protein family HMM PF04087; hypothetical protein 909546..910589 Streptococcus pneumoniae Taiwan19F-14 7687279 YP_002742415.1 CDS topA NC_012469.1 910756 912843 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 910756..912843 Streptococcus pneumoniae Taiwan19F-14 7687311 YP_002742416.1 CDS SPT_0966 NC_012469.1 912949 913308 D identified by match to protein family HMM PF04304; hypothetical protein 912949..913308 Streptococcus pneumoniae Taiwan19F-14 7686507 YP_002742417.1 CDS SPT_0967 NC_012469.1 913401 914033 D identified by match to protein family HMM PF03932; copper sensitivity 913401..914033 Streptococcus pneumoniae Taiwan19F-14 7686222 YP_002742418.1 CDS SPT_0968 NC_012469.1 914077 914733 D identified by match to protein family HMM PF04237; hypothetical protein 914077..914733 Streptococcus pneumoniae Taiwan19F-14 7685344 YP_002742419.1 CDS leuB NC_012469.1 915858 916895 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 915858..916895 Streptococcus pneumoniae Taiwan19F-14 7685229 YP_002742420.1 CDS SPT_0972 NC_012469.1 916892 917161 D identified by match to protein family HMM PF06961; hypothetical protein 916892..917161 Streptococcus pneumoniae Taiwan19F-14 7685780 YP_002742421.1 CDS SPT_0973 NC_012469.1 917165 917524 D hypothetical protein 917165..917524 Streptococcus pneumoniae Taiwan19F-14 7687361 YP_002742422.1 CDS SPT_0974 NC_012469.1 917743 917886 D identified by glimmer; putative; hypothetical protein 917743..917886 Streptococcus pneumoniae Taiwan19F-14 7685335 YP_002742423.1 CDS SPT_0975 NC_012469.1 917892 918158 D identified by glimmer; putative; hypothetical protein 917892..918158 Streptococcus pneumoniae Taiwan19F-14 7686179 YP_002742424.1 CDS SPT_0976 NC_012469.1 918139 918309 D identified by glimmer; putative; hypothetical protein 918139..918309 Streptococcus pneumoniae Taiwan19F-14 7685765 YP_002742425.1 CDS SPT_0977 NC_012469.1 918475 920406 D hypothetical protein 918475..920406 Streptococcus pneumoniae Taiwan19F-14 7685868 YP_002742426.1 CDS SPT_0978 NC_012469.1 920390 921709 D hypothetical protein 920390..921709 Streptococcus pneumoniae Taiwan19F-14 7686930 YP_002742427.1 CDS guaC NC_012469.1 921884 922870 D identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306; guanosine 5'-monophosphate oxidoreductase 921884..922870 Streptococcus pneumoniae Taiwan19F-14 7687204 YP_002742428.1 CDS rnc NC_012469.1 923188 923886 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 923188..923886 Streptococcus pneumoniae Taiwan19F-14 7685605 YP_002742429.1 CDS smc NC_012469.1 923877 927416 D identified by match to protein family HMM PF02463; match to protein family HMM PF06470; match to protein family HMM TIGR02168; chromosome segregation protein SMC 923877..927416 Streptococcus pneumoniae Taiwan19F-14 7685468 YP_002742430.1 CDS SPT_0983 NC_012469.1 927413 928207 D identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 927413..928207 Streptococcus pneumoniae Taiwan19F-14 7687091 YP_002742431.1 CDS SPT_0984 NC_012469.1 928207 929025 D identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 928207..929025 Streptococcus pneumoniae Taiwan19F-14 7687052 YP_002742432.1 CDS SPT_0985 NC_012469.1 929029 930318 D identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; cell division protein FtsY 929029..930318 Streptococcus pneumoniae Taiwan19F-14 7685642 YP_002742433.1 CDS zwf NC_012469.1 930362 931849 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(930362..931849) Streptococcus pneumoniae Taiwan19F-14 7686823 YP_002742434.1 CDS SPT_0987 NC_012469.1 931998 932738 R identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ complement(931998..932738) Streptococcus pneumoniae Taiwan19F-14 7687116 YP_002742435.1 CDS SPT_0988 NC_012469.1 932738 934903 R identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein complement(932738..934903) Streptococcus pneumoniae Taiwan19F-14 7686628 YP_002742436.1 CDS SPT_0989 NC_012469.1 935073 936026 D identified by match to protein family HMM PF02517; caax amino protease family 935073..936026 Streptococcus pneumoniae Taiwan19F-14 7686361 YP_002742437.1 CDS uvrB NC_012469.1 936103 938091 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 936103..938091 Streptococcus pneumoniae Taiwan19F-14 7686977 YP_002742438.1 CDS SPT_0991 NC_012469.1 938101 938664 D acetyltransferase, gnat family 938101..938664 Streptococcus pneumoniae Taiwan19F-14 7685961 YP_002742439.1 CDS SPT_0992 NC_012469.1 938630 939118 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family 938630..939118 Streptococcus pneumoniae Taiwan19F-14 7686327 YP_002742440.1 CDS SPT_0994 NC_012469.1 939191 939658 D identified by match to protein family HMM PF00293; NTP pyrophosphohydrolase including oxidative damage repair enzymes 939191..939658 Streptococcus pneumoniae Taiwan19F-14 7686530 YP_002742441.1 CDS SPT_0993 NC_012469.1 939655 940170 R identified by match to protein family HMM PF02829; match to protein family HMM PF08279; transcriptional regulator, biotin repressor family complement(939655..940170) Streptococcus pneumoniae Taiwan19F-14 7686862 YP_002742442.1 CDS SPT_0995 NC_012469.1 940182 940709 R hypothetical protein complement(940182..940709) Streptococcus pneumoniae Taiwan19F-14 7686219 YP_002742443.1 CDS SPT_0996 NC_012469.1 941005 941568 R integral membrane protein complement(941005..941568) Streptococcus pneumoniae Taiwan19F-14 7686845 YP_002742444.1 CDS coaC NC_012469.1 941552 942103 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(941552..942103) Streptococcus pneumoniae Taiwan19F-14 7686797 YP_002742445.1 CDS coaB NC_012469.1 942115 942804 R identified by match to protein family HMM PF04127; match to protein family HMM TIGR02114; phosphopantothenate--cysteine ligase complement(942115..942804) Streptococcus pneumoniae Taiwan19F-14 7685885 YP_002742446.1 CDS fhs NC_012469.1 943034 944704 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 943034..944704 Streptococcus pneumoniae Taiwan19F-14 7685206 YP_002742447.1 CDS mutY NC_012469.1 945033 946208 D identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 945033..946208 Streptococcus pneumoniae Taiwan19F-14 7685956 YP_002742448.1 CDS SPT_1001 NC_012469.1 946263 946967 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 946263..946967 Streptococcus pneumoniae Taiwan19F-14 7685629 YP_002742449.1 CDS SPT_1002 NC_012469.1 946960 948309 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensor protein YycG 946960..948309 Streptococcus pneumoniae Taiwan19F-14 7685736 YP_002742450.1 CDS SPT_1003 NC_012469.1 948311 949120 D identified by match to protein family HMM PF00753; VicX protein 948311..949120 Streptococcus pneumoniae Taiwan19F-14 7685857 YP_002742451.1 CDS SPT_1004 NC_012469.1 949211 949453 D hypothetical protein 949211..949453 Streptococcus pneumoniae Taiwan19F-14 7687276 YP_002742452.1 CDS SPT_1005 NC_012469.1 949455 949709 D identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385; cytotoxic translational repressor of toxin-antitoxin stability system 949455..949709 Streptococcus pneumoniae Taiwan19F-14 7685883 YP_002742453.1 CDS SPT_1006 NC_012469.1 949756 950529 D identified by match to protein family HMM PF00520; match to protein family HMM PF07885; potassium/ion channel protein 949756..950529 Streptococcus pneumoniae Taiwan19F-14 7685417 YP_002742454.1 CDS SPT_1007 NC_012469.1 950845 952191 R identified by match to protein family HMM PF01609; Spn1 transposase complement(950845..952191) Streptococcus pneumoniae Taiwan19F-14 7686469 YP_002742455.1 CDS ldh NC_012469.1 952500 953486 R Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase complement(952500..953486) Streptococcus pneumoniae Taiwan19F-14 7686761 YP_002742456.1 CDS gyrA NC_012469.1 953680 956148 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 953680..956148 Streptococcus pneumoniae Taiwan19F-14 7686721 YP_002742457.1 CDS SPT_1011 NC_012469.1 956148 956891 D identified by match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase 956148..956891 Streptococcus pneumoniae Taiwan19F-14 7687068 YP_002742458.1 CDS SPT_1012 NC_012469.1 957135 957932 D identified by match to protein family HMM PF01226; formate-nitrate transporter 957135..957932 Streptococcus pneumoniae Taiwan19F-14 7686205 YP_002742459.1 CDS SPT_1015 NC_012469.1 959435 960709 D hypothetical protein 959435..960709 Streptococcus pneumoniae Taiwan19F-14 7686513 YP_002742460.1 CDS truB NC_012469.1 960719 961597 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 960719..961597 Streptococcus pneumoniae Taiwan19F-14 7687196 YP_002742461.1 CDS SPT_1017 NC_012469.1 961838 962179 D identified by glimmer; putative; hypothetical protein 961838..962179 Streptococcus pneumoniae Taiwan19F-14 7686929 YP_002742462.1 CDS udk NC_012469.1 962244 962882 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 962244..962882 Streptococcus pneumoniae Taiwan19F-14 7686055 YP_002742463.1 CDS xseA NC_012469.1 963010 964350 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 963010..964350 Streptococcus pneumoniae Taiwan19F-14 7685491 YP_002742464.1 CDS SPT_1020 NC_012469.1 964328 964540 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 964328..964540 Streptococcus pneumoniae Taiwan19F-14 7686010 YP_002742465.1 CDS SPT_1021 NC_012469.1 964537 965412 D identified by match to protein family HMM PF00348; geranyltranstransferase (Farnesyl-diphosphate synthase)(FPP synthase) 964537..965412 Streptococcus pneumoniae Taiwan19F-14 7686031 YP_002742466.1 CDS tylA NC_012469.1 965405 966220 D identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 965405..966220 Streptococcus pneumoniae Taiwan19F-14 7685267 YP_002742467.1 CDS SPT_1023 NC_012469.1 966213 966644 D identified by match to protein family HMM PF01316; match to protein family HMM PF02863; transcriptional regulator of arginine metabolism expression 966213..966644 Streptococcus pneumoniae Taiwan19F-14 7686008 YP_002742468.1 CDS recN NC_012469.1 966651 968318 D identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634; DNA repair protein RecN 966651..968318 Streptococcus pneumoniae Taiwan19F-14 7685732 YP_002742469.1 CDS SPT_1025 NC_012469.1 968320 969048 D identified by match to protein family HMM PF00149; serine/threonine protein phosphatase 968320..969048 Streptococcus pneumoniae Taiwan19F-14 7686204 YP_002742470.1 CDS lepA NC_012469.1 969127 970950 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 969127..970950 Streptococcus pneumoniae Taiwan19F-14 7686739 YP_002742471.1 CDS SPT_1027 NC_012469.1 971031 971183 R chlorohydrolase complement(971031..971183) Streptococcus pneumoniae Taiwan19F-14 7686836 YP_002742472.1 CDS SPT_1028 NC_012469.1 971363 971839 D identified by match to protein family HMM PF00359; phosphotransferase system sugar-specific EII component 971363..971839 Streptococcus pneumoniae Taiwan19F-14 7686778 YP_002742473.1 CDS SPT_1029 NC_012469.1 971877 972179 D PTS system, galactose-specific IIB component 971877..972179 Streptococcus pneumoniae Taiwan19F-14 7686788 YP_002742474.1 CDS SPT_1031 NC_012469.1 972523 972990 D identified by match to protein family HMM PF01609; transposase (IS4 family) 972523..972990 Streptococcus pneumoniae Taiwan19F-14 7685234 YP_002742475.1 CDS SPT_1032 NC_012469.1 973027 973503 D identified by glimmer; putative; hypothetical protein 973027..973503 Streptococcus pneumoniae Taiwan19F-14 7685400 YP_002742476.1 CDS lacA NC_012469.1 973660 974085 D catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 973660..974085 Streptococcus pneumoniae Taiwan19F-14 7685628 YP_002742477.1 CDS lacB NC_012469.1 974116 974631 D catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 974116..974631 Streptococcus pneumoniae Taiwan19F-14 7686601 YP_002742478.1 CDS lacC NC_012469.1 974642 975571 D catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 974642..975571 Streptococcus pneumoniae Taiwan19F-14 7685228 YP_002742479.1 CDS lacD NC_012469.1 975573 976553 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 975573..976553 Streptococcus pneumoniae Taiwan19F-14 7686698 YP_002742480.1 CDS SPT_1037 NC_012469.1 976786 977622 D identified by match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator LacT 976786..977622 Streptococcus pneumoniae Taiwan19F-14 7686858 YP_002742481.1 CDS SPT_1038 NC_012469.1 977658 977975 D identified by match to protein family HMM PF02255; match to protein family HMM TIGR00823; lactose-specific phosphotransferase enzyme iia component (pts system lactose-specific eiia component) (eiia-lac) (eiii-lac) 977658..977975 Streptococcus pneumoniae Taiwan19F-14 7685461 YP_002742482.1 CDS SPT_1039 NC_012469.1 977975 979666 D pts system lactose-specific eiicb component (eiicb-lac) (eii-lac) 977975..979666 Streptococcus pneumoniae Taiwan19F-14 7685881 YP_002742483.1 CDS lacG2 NC_012469.1 979881 981287 D catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 979881..981287 Streptococcus pneumoniae Taiwan19F-14 7686658 YP_002742484.1 CDS SPT_1041 NC_012469.1 981408 981587 D hypothetical protein 981408..981587 Streptococcus pneumoniae Taiwan19F-14 7687323 YP_002742485.1 CDS SPT_1042 NC_012469.1 981866 982627 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; lactose phosphotransferase system repressor complement(981866..982627) Streptococcus pneumoniae Taiwan19F-14 7686466 YP_002742486.1 CDS nrdF NC_012469.1 982809 983771 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(982809..983771) Streptococcus pneumoniae Taiwan19F-14 7685416 YP_002742487.1 CDS SPT_1044 NC_012469.1 983959 986118 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(983959..986118) Streptococcus pneumoniae Taiwan19F-14 7686273 YP_002742488.1 CDS SPT_1045 NC_012469.1 986199 986417 R identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194; glutaredoxin complement(986199..986417) Streptococcus pneumoniae Taiwan19F-14 7685256 YP_002742489.1 CDS SPT_1046 NC_012469.1 986768 987031 D identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 986768..987031 Streptococcus pneumoniae Taiwan19F-14 7686444 YP_002742490.1 CDS ptsP NC_012469.1 987037 988770 D identified by match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 987037..988770 Streptococcus pneumoniae Taiwan19F-14 7686518 YP_002742491.1 CDS SPT_1048 NC_012469.1 988789 988902 R identified by glimmer; putative; hypothetical protein complement(988789..988902) Streptococcus pneumoniae Taiwan19F-14 7686612 YP_002742492.1 CDS SPT_1049 NC_012469.1 989023 991581 D identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B 989023..991581 Streptococcus pneumoniae Taiwan19F-14 7685983 YP_002742493.1 CDS SPT_1050 NC_012469.1 991791 994910 D identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein E 991791..994910 Streptococcus pneumoniae Taiwan19F-14 7686846 YP_002742494.1 CDS SPT_1053 NC_012469.1 997214 997783 D identified by match to protein family HMM PF04270; pneumococcal histidine triad protein E 997214..997783 Streptococcus pneumoniae Taiwan19F-14 7685753 YP_002742495.1 CDS SPT_1054 NC_012469.1 998078 998707 D hypothetical protein 998078..998707 Streptococcus pneumoniae Taiwan19F-14 7687186 YP_002742496.1 CDS pepT NC_012469.1 998743 999966 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(998743..999966) Streptococcus pneumoniae Taiwan19F-14 7687067 YP_002742497.1 CDS SPT_1056 NC_012469.1 1000325 1000828 D collagen adhesion protein 1000325..1000828 Streptococcus pneumoniae Taiwan19F-14 7685309 YP_002742498.1 CDS SPT_1057 NC_012469.1 1001150 1002910 D identified by glimmer; putative; hypothetical protein 1001150..1002910 Streptococcus pneumoniae Taiwan19F-14 7686781 YP_002742499.1 CDS lepB2 NC_012469.1 1002910 1003461 D identified by match to protein family HMM TIGR02227; signal peptidase I 1002910..1003461 Streptococcus pneumoniae Taiwan19F-14 7687137 YP_002742500.1 CDS SPT_1059 NC_012469.1 1003461 1004702 D hypothetical protein 1003461..1004702 Streptococcus pneumoniae Taiwan19F-14 7686587 YP_002742501.1 CDS srtB NC_012469.1 1004720 1005718 D identified by match to protein family HMM PF07170; match to protein family HMM TIGR03064; sortase, SrtB family 1004720..1005718 Streptococcus pneumoniae Taiwan19F-14 7685755 YP_002742502.1 CDS SPT_1061 NC_012469.1 1005959 1006594 D identified by match to protein family HMM PF07170; surface protein cell wall anchor, sortase_B family 1005959..1006594 Streptococcus pneumoniae Taiwan19F-14 7686033 YP_002742503.1 CDS hemH NC_012469.1 1006697 1007791 D identified by match to protein family HMM PF00762; match to protein family HMM TIGR00109; ferrochelatase 1006697..1007791 Streptococcus pneumoniae Taiwan19F-14 7686838 YP_002742504.1 CDS mscL NC_012469.1 1007833 1008210 R identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220; large conductance mechanosensitive channel protein complement(1007833..1008210) Streptococcus pneumoniae Taiwan19F-14 7686561 YP_002742505.1 CDS SPT_1064 NC_012469.1 1008292 1008723 R identified by match to protein family HMM PF04138; MesH protein complement(1008292..1008723) Streptococcus pneumoniae Taiwan19F-14 7687168 YP_002742506.1 CDS SPT_1065 NC_012469.1 1008846 1009355 D identified by match to protein family HMM PF06177; citrulline cluster-linked protein 1008846..1009355 Streptococcus pneumoniae Taiwan19F-14 7686685 YP_002742507.1 CDS asd NC_012469.1 1009870 1010946 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1009870..1010946 Streptococcus pneumoniae Taiwan19F-14 7685570 YP_002742508.1 CDS dapA NC_012469.1 1011002 1011937 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1011002..1011937 Streptococcus pneumoniae Taiwan19F-14 7686948 YP_002742509.1 CDS trmE NC_012469.1 1011984 1013357 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(1011984..1013357) Streptococcus pneumoniae Taiwan19F-14 7687390 YP_002742510.1 CDS SPT_1070 NC_012469.1 1013493 1013675 R 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase complement(1013493..1013675) Streptococcus pneumoniae Taiwan19F-14 7686567 YP_002742511.1 CDS tdk NC_012469.1 1013799 1014389 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1013799..1014389 Streptococcus pneumoniae Taiwan19F-14 7685854 YP_002742512.1 CDS prfA NC_012469.1 1014386 1015465 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1014386..1015465 Streptococcus pneumoniae Taiwan19F-14 7685985 YP_002742513.1 CDS hemK NC_012469.1 1015465 1016304 D identified by match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00536; match to protein family HMM TIGR03387; protein-(glutamine-N5) methyltransferase, release factor-specific 1015465..1016304 Streptococcus pneumoniae Taiwan19F-14 7685873 YP_002742514.1 CDS SPT_1074 NC_012469.1 1016288 1016890 D identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 1016288..1016890 Streptococcus pneumoniae Taiwan19F-14 7685247 YP_002742515.1 CDS SPT_1075 NC_012469.1 1016892 1017323 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 1016892..1017323 Streptococcus pneumoniae Taiwan19F-14 7687019 YP_002742516.1 CDS glyA NC_012469.1 1017385 1018641 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1017385..1018641 Streptococcus pneumoniae Taiwan19F-14 7687250 YP_002742517.1 CDS SPT_1077 NC_012469.1 1018649 1019623 D hypothetical protein 1018649..1019623 Streptococcus pneumoniae Taiwan19F-14 7687059 YP_002742518.1 CDS SPT_1078 NC_012469.1 1019623 1020237 D pneumococcal vaccine antigen A 1019623..1020237 Streptococcus pneumoniae Taiwan19F-14 7687081 YP_002742519.1 CDS SPT_1079 NC_012469.1 1020311 1021285 D identified by match to protein family HMM PF06207; hypothetical protein 1020311..1021285 Streptococcus pneumoniae Taiwan19F-14 7686667 YP_002742520.1 CDS rumA1 NC_012469.1 1021359 1022990 D identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA 1021359..1022990 Streptococcus pneumoniae Taiwan19F-14 7687031 YP_002742521.1 CDS SPT_1081 NC_012469.1 1023728 1023946 D hypothetical protein 1023728..1023946 Streptococcus pneumoniae Taiwan19F-14 7685655 YP_002742522.1 CDS SPT_1082 NC_012469.1 1024339 1025364 D identified by match to protein family HMM PF01497; ABC transporter substrate-binding protein - iron transport 1024339..1025364 Streptococcus pneumoniae Taiwan19F-14 7686592 YP_002742523.1 CDS SPT_1083 NC_012469.1 1025354 1026361 D identified by match to protein family HMM PF01032; iron-compound ABC transporter, permease protein 1025354..1026361 Streptococcus pneumoniae Taiwan19F-14 7686434 YP_002742524.1 CDS SPT_1084 NC_012469.1 1026361 1027368 D identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 1026361..1027368 Streptococcus pneumoniae Taiwan19F-14 7686166 YP_002742525.1 CDS SPT_1085 NC_012469.1 1027368 1028162 D identified by match to protein family HMM PF00005; ferric enterobactin transport ATP-binding protein FepC 1027368..1028162 Streptococcus pneumoniae Taiwan19F-14 7686245 YP_002742526.1 CDS SPT_1086 NC_012469.1 1028850 1029164 D hypothetical protein 1028850..1029164 Streptococcus pneumoniae Taiwan19F-14 7686525 YP_002742527.1 CDS SPT_1087 NC_012469.1 1029478 1031118 D identified by match to protein family HMM PF03389; MobA/MobL family protein 1029478..1031118 Streptococcus pneumoniae Taiwan19F-14 7686195 YP_002742528.1 CDS SPT_1088 NC_012469.1 1031192 1031365 D identified by glimmer; putative; hypothetical protein 1031192..1031365 Streptococcus pneumoniae Taiwan19F-14 7686626 YP_002742529.1 CDS SPT_1091 NC_012469.1 1033259 1033792 D hypothetical protein 1033259..1033792 Streptococcus pneumoniae Taiwan19F-14 7685641 YP_002742530.1 CDS SPT_1092 NC_012469.1 1033919 1034641 D identified by match to protein family HMM TIGR01714; putative phage-associated protein 1033919..1034641 Streptococcus pneumoniae Taiwan19F-14 7687085 YP_002742531.1 CDS SPT_1093 NC_012469.1 1035325 1035486 D hypothetical protein 1035325..1035486 Streptococcus pneumoniae Taiwan19F-14 7687008 YP_002742532.1 CDS SPT_1096 NC_012469.1 1037525 1038091 D hypothetical protein 1037525..1038091 Streptococcus pneumoniae Taiwan19F-14 7685220 YP_002742533.1 CDS SPT_1097 NC_012469.1 1038412 1038600 D hypothetical protein 1038412..1038600 Streptococcus pneumoniae Taiwan19F-14 7685827 YP_002742534.1 CDS SPT_1098 NC_012469.1 1038662 1039420 D identified by glimmer; putative; hypothetical protein 1038662..1039420 Streptococcus pneumoniae Taiwan19F-14 7687310 YP_002742535.1 CDS SPT_1099 NC_012469.1 1039478 1040332 D identified by match to protein family HMM PF03747; ADP-ribosylglycohydrolase superfamily 1039478..1040332 Streptococcus pneumoniae Taiwan19F-14 7686703 YP_002742536.1 CDS SPT_1100 NC_012469.1 1040444 1041328 D identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147; hypothetical protein 1040444..1041328 Streptococcus pneumoniae Taiwan19F-14 7685237 YP_002742537.1 CDS SPT_1104 NC_012469.1 1043505 1043807 D identified by glimmer; putative; hypothetical protein 1043505..1043807 Streptococcus pneumoniae Taiwan19F-14 7686884 YP_002742538.1 CDS SPT_1105 NC_012469.1 1043863 1044291 D identified by match to protein family HMM PF00583; aminoglycoside 6'-N-acetyltransferase 1043863..1044291 Streptococcus pneumoniae Taiwan19F-14 7685616 YP_002742539.1 CDS SPT_1106 NC_012469.1 1044388 1044645 D identified by glimmer; putative; hypothetical protein 1044388..1044645 Streptococcus pneumoniae Taiwan19F-14 7686467 YP_002742540.1 CDS SPT_1107 NC_012469.1 1044674 1044958 D hypothetical ABC transporter ATP-binding protein 1044674..1044958 Streptococcus pneumoniae Taiwan19F-14 7686786 YP_002742541.1 CDS SPT_1109 NC_012469.1 1045592 1045786 D transposase 1045592..1045786 Streptococcus pneumoniae Taiwan19F-14 7686569 YP_002742542.1 CDS SPT_1110 NC_012469.1 1046050 1047279 D identified by match to protein family HMM PF01098; cell division protein FtsW 1046050..1047279 Streptococcus pneumoniae Taiwan19F-14 7685479 YP_002742543.1 CDS ppc NC_012469.1 1047299 1049995 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 1047299..1049995 Streptococcus pneumoniae Taiwan19F-14 7685939 YP_002742544.1 CDS SPT_1112 NC_012469.1 1050408 1051412 D identified by match to protein family HMM PF04392; ABC transporter substrate-binding protein 1050408..1051412 Streptococcus pneumoniae Taiwan19F-14 7687120 YP_002742545.1 CDS SPT_1113 NC_012469.1 1051481 1052347 D identified by match to protein family HMM PF02653; ABC transporter 1051481..1052347 Streptococcus pneumoniae Taiwan19F-14 7686869 YP_002742546.1 CDS SPT_1114 NC_012469.1 1052344 1053102 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1052344..1053102 Streptococcus pneumoniae Taiwan19F-14 7685703 YP_002742547.1 CDS dnaG NC_012469.1 1053192 1054952 D synthesizes RNA primers at the replication forks; DNA primase 1053192..1054952 Streptococcus pneumoniae Taiwan19F-14 7686421 YP_002742548.1 CDS SPT_1116 NC_012469.1 1054955 1056064 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1054955..1056064 Streptococcus pneumoniae Taiwan19F-14 7687229 YP_002742549.1 CDS SPT_1117 NC_012469.1 1056078 1056407 D identified by match to protein family HMM PF01883; N-6 Adenine-specific DNA methylase YitW 1056078..1056407 Streptococcus pneumoniae Taiwan19F-14 7685833 YP_002742550.1 CDS SPT_1118 NC_012469.1 1056522 1057565 D identified by match to protein family HMM PF00534; glycosyl transferase CpoA 1056522..1057565 Streptococcus pneumoniae Taiwan19F-14 7686135 YP_002742551.1 CDS SPT_1119 NC_012469.1 1057581 1058906 D identified by match to protein family HMM PF00534; glycosyl transferase, group 1 1057581..1058906 Streptococcus pneumoniae Taiwan19F-14 7685325 YP_002742552.1 CDS SPT_1120 NC_012469.1 1058937 1059113 D identified by match to protein family HMM PF04024; hypothetical protein 1058937..1059113 Streptococcus pneumoniae Taiwan19F-14 7687372 YP_002742553.1 CDS SPT_1121 NC_012469.1 1059172 1059306 D hypothetical protein 1059172..1059306 Streptococcus pneumoniae Taiwan19F-14 7686054 YP_002742554.1 CDS obgE NC_012469.1 1059376 1060680 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1059376..1060680 Streptococcus pneumoniae Taiwan19F-14 7686933 YP_002742555.1 CDS SPT_1123 NC_012469.1 1060690 1060848 D hypothetical protein 1060690..1060848 Streptococcus pneumoniae Taiwan19F-14 7686866 YP_002742556.1 CDS SPT_1127 NC_012469.1 1063402 1064661 D adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1063402..1064661 Streptococcus pneumoniae Taiwan19F-14 7686935 YP_002742557.1 CDS SPT_1128 NC_012469.1 1064677 1065228 D identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein 1064677..1065228 Streptococcus pneumoniae Taiwan19F-14 7686040 YP_002742558.1 CDS SPT_1129 NC_012469.1 1065221 1066498 D identified by match to protein family HMM PF00571; match to protein family HMM PF07085; match to protein family HMM PF08279; cytosolic protein containing multiple CBS domains 1065221..1066498 Streptococcus pneumoniae Taiwan19F-14 7686270 YP_002742559.1 CDS map NC_012469.1 1066514 1067374 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase 1066514..1067374 Streptococcus pneumoniae Taiwan19F-14 7687225 YP_002742560.1 CDS SPT_1131 NC_012469.1 1067473 1068153 D mobile genetic element 1067473..1068153 Streptococcus pneumoniae Taiwan19F-14 7687371 YP_002742561.1 CDS SPT_1132 NC_012469.1 1068170 1068559 D identified by match to protein family HMM PF01609; transposase (IS4 family) 1068170..1068559 Streptococcus pneumoniae Taiwan19F-14 7686328 YP_002742562.1 CDS pcrA NC_012469.1 1068751 1071042 D identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073; ATP-dependent DNA helicase PcrA 1068751..1071042 Streptococcus pneumoniae Taiwan19F-14 7685627 YP_002742563.1 CDS radC NC_012469.1 1071085 1071765 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1071085..1071765 Streptococcus pneumoniae Taiwan19F-14 7685934 YP_002742564.1 CDS SPT_1134 NC_012469.1 1071762 1072451 R identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase, class I complement(1071762..1072451) Streptococcus pneumoniae Taiwan19F-14 7686446 YP_002742565.1 CDS SPT_1136 NC_012469.1 1072469 1073110 R modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex complement(1072469..1073110) Streptococcus pneumoniae Taiwan19F-14 7686985 YP_002742566.1 CDS SPT_1137 NC_012469.1 1073193 1073336 R hypothetical protein complement(1073193..1073336) Streptococcus pneumoniae Taiwan19F-14 7687383 YP_002742567.1 CDS SPT_1138 NC_012469.1 1073416 1073763 R identified by match to protein family HMM PF08866; hypothetical protein complement(1073416..1073763) Streptococcus pneumoniae Taiwan19F-14 7685738 YP_002742568.1 CDS SPT_1139 NC_012469.1 1073768 1074883 R identified by match to protein family HMM PF00266; cysteine desulfurase complement(1073768..1074883) Streptococcus pneumoniae Taiwan19F-14 7685917 YP_002742569.1 CDS SPT_1140 NC_012469.1 1074893 1075852 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1074893..1075852) Streptococcus pneumoniae Taiwan19F-14 7685507 YP_002742570.1 CDS SPT_1141 NC_012469.1 1075965 1076534 R identified by match to protein family HMM PF01928; adenylate cyclase complement(1075965..1076534) Streptococcus pneumoniae Taiwan19F-14 7686318 YP_002742571.1 CDS SPT_1142 NC_012469.1 1076662 1077333 D identified by match to protein family HMM PF04607; GTP pyrophosphokinase 1076662..1077333 Streptococcus pneumoniae Taiwan19F-14 7687184 YP_002742572.1 CDS ppnK NC_012469.1 1077317 1078135 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1077317..1078135 Streptococcus pneumoniae Taiwan19F-14 7685762 YP_002742573.1 CDS SPT_1144 NC_012469.1 1078132 1079028 D identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase, RluD subfamily 1078132..1079028 Streptococcus pneumoniae Taiwan19F-14 7687288 YP_002742574.1 CDS eutD NC_012469.1 1079072 1080046 D in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 1079072..1080046 Streptococcus pneumoniae Taiwan19F-14 7685383 YP_002742575.1 CDS SPT_1149 NC_012469.1 1081939 1082238 R identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein complement(1081939..1082238) Streptococcus pneumoniae Taiwan19F-14 7686256 YP_002742576.1 CDS SPT_1150 NC_012469.1 1082640 1083338 D identified by match to protein family HMM PF06912; hypothetical protein 1082640..1083338 Streptococcus pneumoniae Taiwan19F-14 7687153 YP_002742577.1 CDS rplU NC_012469.1 1083526 1083840 D identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1083526..1083840 Streptococcus pneumoniae Taiwan19F-14 7685895 YP_002742578.1 CDS SPT_1152 NC_012469.1 1083856 1084200 D identified by match to protein family HMM PF04327; hypothetical protein 1083856..1084200 Streptococcus pneumoniae Taiwan19F-14 7686519 YP_002742579.1 CDS rpmA NC_012469.1 1084217 1084510 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1084217..1084510 Streptococcus pneumoniae Taiwan19F-14 7687117 YP_002742580.1 CDS SPT_1154 NC_012469.1 1084750 1084920 R identified by glimmer; putative; hypothetical protein complement(1084750..1084920) Streptococcus pneumoniae Taiwan19F-14 7686894 YP_002742581.1 CDS SPT_1155 NC_012469.1 1084892 1085020 R hypothetical protein complement(1084892..1085020) Streptococcus pneumoniae Taiwan19F-14 7686696 YP_002742582.1 CDS ribF NC_012469.1 1085358 1086275 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1085358..1086275 Streptococcus pneumoniae Taiwan19F-14 7686384 YP_002742583.1 CDS SPT_1157 NC_012469.1 1086368 1087216 R identified by match to protein family HMM PF02588; hypothetical protein complement(1086368..1087216) Streptococcus pneumoniae Taiwan19F-14 7687147 YP_002742584.1 CDS SPT_1158 NC_012469.1 1087358 1088197 D identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 1087358..1088197 Streptococcus pneumoniae Taiwan19F-14 7686899 YP_002742585.1 CDS SPT_1159 NC_012469.1 1088304 1088579 D identified by match to protein family HMM PF00216; DNA-binding protein HU 1 (DNA-binding protein II) (HB) 1088304..1088579 Streptococcus pneumoniae Taiwan19F-14 7686173 YP_002742586.1 CDS SPT_1160 NC_012469.1 1089006 1090907 D identified by match to protein family HMM PF00005; ATPase component of ABC transporter with duplicated ATPase domains 1089006..1090907 Streptococcus pneumoniae Taiwan19F-14 7686208 YP_002742587.1 CDS SPT_1161 NC_012469.1 1090910 1091773 D identified by match to protein family HMM TIGR01716; transcriptional regulator 1090910..1091773 Streptococcus pneumoniae Taiwan19F-14 7686501 YP_002742588.1 CDS SPT_1162 NC_012469.1 1091853 1093031 D identified by match to protein family HMM PF07690; macrolide ABC transporter permease 1091853..1093031 Streptococcus pneumoniae Taiwan19F-14 7686319 YP_002742589.1 CDS ligA NC_012469.1 1093124 1095082 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1093124..1095082 Streptococcus pneumoniae Taiwan19F-14 7685448 YP_002742590.1 CDS pulA NC_012469.1 1095194 1097473 D identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02104; pullulanase, type I 1095194..1097473 Streptococcus pneumoniae Taiwan19F-14 7685924 YP_002742591.1 CDS SPT_1165 NC_012469.1 1098017 1099441 D identified by match to protein family HMM PF00171; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase 1098017..1099441 Streptococcus pneumoniae Taiwan19F-14 7686495 YP_002742592.1 CDS glgB NC_012469.1 1099925 1101853 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1099925..1101853 Streptococcus pneumoniae Taiwan19F-14 7686266 YP_002742593.1 CDS glgC NC_012469.1 1101843 1102985 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1101843..1102985 Streptococcus pneumoniae Taiwan19F-14 7685399 YP_002742594.1 CDS glgD NC_012469.1 1102975 1104114 D identified by match to protein family HMM PF00483; match to protein family HMM TIGR02092; glucose-1-phosphate adenylyltransferase, GlgD subunit 1102975..1104114 Streptococcus pneumoniae Taiwan19F-14 7686075 YP_002742595.1 CDS glgA NC_012469.1 1104111 1105544 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 1104111..1105544 Streptococcus pneumoniae Taiwan19F-14 7686743 YP_002742596.1 CDS SPT_1172 NC_012469.1 1106257 1107372 D identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 1106257..1107372 Streptococcus pneumoniae Taiwan19F-14 7685900 YP_002742597.1 CDS SPT_1171 NC_012469.1 1107369 1107815 R identified by match to protein family HMM PF07997; hypothetical protein complement(1107369..1107815) Streptococcus pneumoniae Taiwan19F-14 7686875 YP_002742598.1 CDS eno NC_012469.1 1107979 1109283 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1107979..1109283 Streptococcus pneumoniae Taiwan19F-14 7686663 YP_002742599.1 CDS SPT_1176 NC_012469.1 1110970 1111221 R transposase complement(1110970..1111221) Streptococcus pneumoniae Taiwan19F-14 7686693 YP_002742600.1 CDS SPT_1177 NC_012469.1 1111400 1111729 R identified by match to protein family HMM PF01710; transposase complement(1111400..1111729) Streptococcus pneumoniae Taiwan19F-14 7685444 YP_002742601.1 CDS rexB NC_012469.1 1112231 1115530 D identified by match to protein family HMM TIGR02774; ATP-dependent nuclease subunit B 1112231..1115530 Streptococcus pneumoniae Taiwan19F-14 7686373 YP_002742602.1 CDS addA NC_012469.1 1115527 1119177 D identified by match to protein family HMM PF00580; match to protein family HMM TIGR02785; recombination helicase AddA 1115527..1119177 Streptococcus pneumoniae Taiwan19F-14 7686343 YP_002742603.1 CDS SPT_1180 NC_012469.1 1119392 1120570 D hypothetical protein 1119392..1120570 Streptococcus pneumoniae Taiwan19F-14 7686730 YP_002742604.1 CDS SPT_1181 NC_012469.1 1120779 1126793 D identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05342; match to protein family HMM PF07501; match to protein family HMM PF07580; match to protein family HMM PF07581; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; immunoglobulin A1 protease 1120779..1126793 Streptococcus pneumoniae Taiwan19F-14 7685636 YP_002742605.1 CDS rbgA NC_012469.1 1127241 1128092 D essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1127241..1128092 Streptococcus pneumoniae Taiwan19F-14 7686562 YP_002742606.1 CDS rnhB NC_012469.1 1128079 1128858 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1128079..1128858 Streptococcus pneumoniae Taiwan19F-14 7686111 YP_002742607.1 CDS SPT_1184 NC_012469.1 1128874 1130424 D identified by match to protein family HMM PF00654; match to protein family HMM PF02080; voltage-gated chloride channel family protein 1128874..1130424 Streptococcus pneumoniae Taiwan19F-14 7686293 YP_002742608.1 CDS xerS NC_012469.1 1130918 1131988 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS 1130918..1131988 Streptococcus pneumoniae Taiwan19F-14 7686394 YP_002742609.1 CDS SPT_1186 NC_012469.1 1132061 1133050 R identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate protein ligase A complement(1132061..1133050) Streptococcus pneumoniae Taiwan19F-14 7685726 YP_002742610.1 CDS lpdA NC_012469.1 1133114 1134799 R identified by match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR01350; dihydrolipoyl dehydrogenase complement(1133114..1134799) Streptococcus pneumoniae Taiwan19F-14 7685217 YP_002742611.1 CDS SPT_1188 NC_012469.1 1134863 1135906 R unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase complement(1134863..1135906) Streptococcus pneumoniae Taiwan19F-14 7687111 YP_002742612.1 CDS SPT_1189 NC_012469.1 1136124 1137116 R identified by match to protein family HMM PF02779; match to protein family HMM PF02780; pyruvate dehydrogenase E1 component subunit beta complement(1136124..1137116) Streptococcus pneumoniae Taiwan19F-14 7686709 YP_002742613.1 CDS SPT_1190 NC_012469.1 1137132 1138100 R identified by match to protein family HMM PF00676; pyruvate dehydrogenase E1 component subunit alpha complement(1137132..1138100) Streptococcus pneumoniae Taiwan19F-14 7685820 YP_002742614.1 CDS SPT_1191 NC_012469.1 1138254 1139615 R identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; mate efflux family protein complement(1138254..1139615) Streptococcus pneumoniae Taiwan19F-14 7687057 YP_002742615.1 CDS pyrC NC_012469.1 1139900 1141168 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1139900..1141168) Streptococcus pneumoniae Taiwan19F-14 7686322 YP_002742616.1 CDS SPT_1193 NC_012469.1 1141181 1141645 R identified by match to protein family HMM PF00293; mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase) complement(1141181..1141645) Streptococcus pneumoniae Taiwan19F-14 7685500 YP_002742617.1 CDS ung NC_012469.1 1141655 1142308 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1141655..1142308) Streptococcus pneumoniae Taiwan19F-14 7686239 YP_002742618.1 CDS SPT_1195 NC_012469.1 1142613 1143092 R identified by glimmer; putative; hypothetical protein complement(1142613..1143092) Streptococcus pneumoniae Taiwan19F-14 7686355 YP_002742619.1 CDS SPT_1196 NC_012469.1 1143106 1143819 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; HAD superfamily (subfamily IA) hydrolase complement(1143106..1143819) Streptococcus pneumoniae Taiwan19F-14 7686891 YP_002742620.1 CDS SPT_1197 NC_012469.1 1144278 1144658 R identified by match to protein family HMM PF03610; match to protein family HMM TIGR02364; phosphotransferase mannnose-specific family component IIA complement(1144278..1144658) Streptococcus pneumoniae Taiwan19F-14 7685758 YP_002742621.1 CDS SPT_1198 NC_012469.1 1145080 1147560 R identified by match to protein family HMM PF04270; match to protein family HMM TIGR01363; pneumococcal histidine triad protein B complement(1145080..1147560) Streptococcus pneumoniae Taiwan19F-14 7687092 YP_002742622.1 CDS SPT_1199 NC_012469.1 1147568 1148485 R identified by match to protein family HMM PF01297; zinc-binding lipoprotein AdcA complement(1147568..1148485) Streptococcus pneumoniae Taiwan19F-14 7686454 YP_002742623.1 CDS SPT_1200 NC_012469.1 1148628 1150019 R identified by match to protein family HMM PF00324; amino acid permease family protein complement(1148628..1150019) Streptococcus pneumoniae Taiwan19F-14 7686027 YP_002742624.1 CDS SPT_1201 NC_012469.1 1150393 1150950 R identified by match to protein family HMM PF00578; match to protein family HMM PF08534; thioredoxin family protein complement(1150393..1150950) Streptococcus pneumoniae Taiwan19F-14 7686681 YP_002742625.1 CDS SPT_1202 NC_012469.1 1150961 1151668 R identified by match to protein family HMM PF02683; cytochrome c-type biogenesis protein CcdA complement(1150961..1151668) Streptococcus pneumoniae Taiwan19F-14 7687173 YP_002742626.1 CDS SPT_1203 NC_012469.1 1151899 1152315 R hypothetical protein complement(1151899..1152315) Streptococcus pneumoniae Taiwan19F-14 7685909 YP_002742627.1 CDS SPT_1204 NC_012469.1 1152340 1152540 R hypothetical protein complement(1152340..1152540) Streptococcus pneumoniae Taiwan19F-14 7687210 YP_002742628.1 CDS SPT_1205 NC_012469.1 1152733 1152858 D identified by glimmer; putative; hypothetical protein 1152733..1152858 Streptococcus pneumoniae Taiwan19F-14 7687401 YP_002742629.1 CDS SPT_1206 NC_012469.1 1153006 1153335 R identified by match to protein family HMM PF01710; transposase complement(1153006..1153335) Streptococcus pneumoniae Taiwan19F-14 7685464 YP_002742630.1 CDS SPT_1210 NC_012469.1 1155040 1156803 R identified by match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase family protein complement(1155040..1156803) Streptococcus pneumoniae Taiwan19F-14 7685809 YP_002742631.1 CDS SPT_1211 NC_012469.1 1156812 1157402 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1156812..1157402) Streptococcus pneumoniae Taiwan19F-14 7685887 YP_002742632.1 CDS SPT_1212 NC_012469.1 1157500 1157979 R identified by match to protein family HMM PF04394; hypothetical protein complement(1157500..1157979) Streptococcus pneumoniae Taiwan19F-14 7686559 YP_002742633.1 CDS mtnN NC_012469.1 1158068 1158760 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(1158068..1158760) Streptococcus pneumoniae Taiwan19F-14 7685537 YP_002742634.1 CDS SPT_1214 NC_012469.1 1158777 1159091 R hypothetical protein complement(1158777..1159091) Streptococcus pneumoniae Taiwan19F-14 7685986 YP_002742635.1 CDS SPT_1215 NC_012469.1 1159103 1159648 R identified by match to protein family HMM PF00293; ADP-ribose pyrophosphatase complement(1159103..1159648) Streptococcus pneumoniae Taiwan19F-14 7685640 YP_002742636.1 CDS glmU NC_012469.1 1159658 1161037 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(1159658..1161037) Streptococcus pneumoniae Taiwan19F-14 7686975 YP_002742637.1 CDS SPT_1217 NC_012469.1 1161181 1161969 D identified by match to protein family HMM PF01183; lyzozyme M1 1161181..1161969 Streptococcus pneumoniae Taiwan19F-14 7686199 YP_002742638.1 CDS SPT_1218 NC_012469.1 1162064 1162906 D identified by match to protein family HMM PF04018; integral membrane protein 1162064..1162906 Streptococcus pneumoniae Taiwan19F-14 7687405 YP_002742639.1 CDS SPT_1219 NC_012469.1 1162937 1163389 D identified by match to protein family HMM PF04073; regulatory protein 1162937..1163389 Streptococcus pneumoniae Taiwan19F-14 7685458 YP_002742640.1 CDS SPT_1220 NC_012469.1 1163389 1164009 D identified by match to protein family HMM PF00300; phosphoglycerate mutase 1163389..1164009 Streptococcus pneumoniae Taiwan19F-14 7685625 YP_002742641.1 CDS prsA NC_012469.1 1165228 1166169 R cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA complement(1165228..1166169) Streptococcus pneumoniae Taiwan19F-14 7685266 YP_002742642.1 CDS SPT_1223 NC_012469.1 1166236 1166913 R identified by match to protein family HMM PF01596; match to protein family HMM PF08241; O-methyltransferase family protein complement(1166236..1166913) Streptococcus pneumoniae Taiwan19F-14 7687289 YP_002742643.1 CDS pepF1 NC_012469.1 1166951 1168762 R identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F complement(1166951..1168762) Streptococcus pneumoniae Taiwan19F-14 7685739 YP_002742644.1 CDS SPT_1225 NC_012469.1 1168781 1169734 R identified by match to protein family HMM PF06054; competence protein complement(1168781..1169734) Streptococcus pneumoniae Taiwan19F-14 7686543 YP_002742645.1 CDS tehB NC_012469.1 1169807 1170667 R with TehA confers resistance to tellurite; tellurite resistance protein TehB complement(1169807..1170667) Streptococcus pneumoniae Taiwan19F-14 7685800 YP_002742646.1 CDS smpB NC_012469.1 1170683 1171150 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1170683..1171150) Streptococcus pneumoniae Taiwan19F-14 7686226 YP_002742647.1 CDS rnr NC_012469.1 1171113 1173467 R identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM PF08206; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; ribonuclease R complement(1171113..1173467) Streptococcus pneumoniae Taiwan19F-14 7686851 YP_002742648.1 CDS secG NC_012469.1 1173569 1173802 R identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG complement(1173569..1173802) Streptococcus pneumoniae Taiwan19F-14 7687223 YP_002742649.1 CDS rpmG NC_012469.1 1173842 1173991 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(1173842..1173991) Streptococcus pneumoniae Taiwan19F-14 7685926 YP_002742650.1 CDS SPT_1231 NC_012469.1 1173991 1175190 R identified by match to protein family HMM PF07690; multidrug resistance protein MdtG complement(1173991..1175190) Streptococcus pneumoniae Taiwan19F-14 7687230 YP_002742651.1 CDS coaE NC_012469.1 1175177 1175782 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(1175177..1175782) Streptococcus pneumoniae Taiwan19F-14 7686063 YP_002742652.1 CDS mutM NC_012469.1 1175782 1176606 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(1175782..1176606) Streptococcus pneumoniae Taiwan19F-14 7686296 YP_002742653.1 CDS era NC_012469.1 1176655 1177554 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(1176655..1177554) Streptococcus pneumoniae Taiwan19F-14 7686967 YP_002742654.1 CDS SPT_1235 NC_012469.1 1177571 1177966 R identified by match to protein family HMM PF01219; diacylglycerol kinase (dagk) (diglyceride kinase)(dgk) complement(1177571..1177966) Streptococcus pneumoniae Taiwan19F-14 7686076 YP_002742655.1 CDS SPT_1236 NC_012469.1 1177947 1178444 R identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043; putative metalloprotease complement(1177947..1178444) Streptococcus pneumoniae Taiwan19F-14 7685455 YP_002742656.1 CDS SPT_1237 NC_012469.1 1178549 1180204 D identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin/fibrinogen binding protein 1178549..1180204 Streptococcus pneumoniae Taiwan19F-14 7686349 YP_002742657.1 CDS SPT_1238 NC_012469.1 1180265 1182373 R identified by match to protein family HMM PF01473; match to protein family HMM PF01832; endo-beta-N-acetylglucosaminidase complement(1180265..1182373) Streptococcus pneumoniae Taiwan19F-14 7687338 YP_002742658.1 CDS SPT_1239 NC_012469.1 1182472 1183410 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B complement(1182472..1183410) Streptococcus pneumoniae Taiwan19F-14 7686692 YP_002742659.1 CDS SPT_1240 NC_012469.1 1183421 1184221 R responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit complement(1183421..1184221) Streptococcus pneumoniae Taiwan19F-14 7685776 YP_002742660.1 CDS SPT_1241 NC_012469.1 1184471 1184851 R identified by match to protein family HMM PF00903; lactoylglutathione lyase complement(1184471..1184851) Streptococcus pneumoniae Taiwan19F-14 7687358 YP_002742661.1 CDS rplT NC_012469.1 1184909 1185268 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1184909..1185268) Streptococcus pneumoniae Taiwan19F-14 7685232 YP_002742662.1 CDS rpmI NC_012469.1 1185320 1185520 R identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 complement(1185320..1185520) Streptococcus pneumoniae Taiwan19F-14 7686791 YP_002742663.1 CDS infC NC_012469.1 1185553 1186110 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1185553..1186110) Streptococcus pneumoniae Taiwan19F-14 7685382 YP_002742664.1 CDS SPT_1245 NC_012469.1 1186394 1187578 R hypothetical protein complement(1186394..1187578) Streptococcus pneumoniae Taiwan19F-14 7687084 YP_002742665.1 CDS SPT_1246 NC_012469.1 1187582 1188169 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1187582..1188169) Streptococcus pneumoniae Taiwan19F-14 7686657 YP_002742666.1 CDS SPT_1247 NC_012469.1 1188568 1190808 R identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; DNA internalization-related competence protein ComEC/Rec2 complement(1188568..1190808) Streptococcus pneumoniae Taiwan19F-14 7686059 YP_002742667.1 CDS SPT_1248 NC_012469.1 1190792 1191442 R identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426; match to protein family HMM TIGR01259; competence protein complement(1190792..1191442) Streptococcus pneumoniae Taiwan19F-14 7685624 YP_002742668.1 CDS SPT_1249 NC_012469.1 1191510 1192079 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family complement(1191510..1192079) Streptococcus pneumoniae Taiwan19F-14 7686745 YP_002742669.1 CDS SPT_1253 NC_012469.1 1193767 1193994 R TfoX N- domain family protein complement(1193767..1193994) Streptococcus pneumoniae Taiwan19F-14 7685903 YP_002742670.1 CDS SPT_1254 NC_012469.1 1193997 1194497 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family complement(1193997..1194497) Streptococcus pneumoniae Taiwan19F-14 7686774 YP_002742671.1 CDS SPT_1256 NC_012469.1 1194587 1194712 D identified by glimmer; putative; hypothetical protein 1194587..1194712 Streptococcus pneumoniae Taiwan19F-14 7686465 YP_002742672.1 CDS SPT_1255 NC_012469.1 1194690 1195658 R identified by match to protein family HMM PF02562; PhoH family protein complement(1194690..1195658) Streptococcus pneumoniae Taiwan19F-14 7686762 YP_002742673.1 CDS SPT_1257 NC_012469.1 1195744 1195959 R identified by match to protein family HMM PF06855; hypothetical protein complement(1195744..1195959) Streptococcus pneumoniae Taiwan19F-14 7686538 YP_002742674.1 CDS SPT_1258 NC_012469.1 1195968 1196861 R s1 RNA binding domain protein complement(1195968..1196861) Streptococcus pneumoniae Taiwan19F-14 7686093 YP_002742675.1 CDS frr NC_012469.1 1196882 1197439 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1196882..1197439) Streptococcus pneumoniae Taiwan19F-14 7685393 YP_002742676.1 CDS pyrH NC_012469.1 1197448 1198185 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1197448..1198185) Streptococcus pneumoniae Taiwan19F-14 7687237 YP_002742677.1 CDS trmFO NC_012469.1 1198269 1199603 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(1198269..1199603) Streptococcus pneumoniae Taiwan19F-14 7685341 YP_002742678.1 CDS SPT_1262 NC_012469.1 1199790 1200668 R identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; hypothetical protein complement(1199790..1200668) Streptococcus pneumoniae Taiwan19F-14 7685483 YP_002742679.1 CDS SPT_1263 NC_012469.1 1200671 1200988 R in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA complement(1200671..1200988) Streptococcus pneumoniae Taiwan19F-14 7685223 YP_002742680.1 CDS SPT_1264 NC_012469.1 1201028 1201918 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' complement(1201028..1201918) Streptococcus pneumoniae Taiwan19F-14 7686726 YP_002742681.1 CDS tmk NC_012469.1 1201915 1202553 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1201915..1202553) Streptococcus pneumoniae Taiwan19F-14 7687222 YP_002742682.1 CDS proC NC_012469.1 1202773 1203570 R identified by match to protein family HMM PF01210; match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR00112; pyrroline-5-carboxylate reductase complement(1202773..1203570) Streptococcus pneumoniae Taiwan19F-14 7686197 YP_002742683.1 CDS proA NC_012469.1 1203574 1204836 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1203574..1204836) Streptococcus pneumoniae Taiwan19F-14 7685520 YP_002742684.1 CDS proB NC_012469.1 1204846 1205955 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1204846..1205955) Streptococcus pneumoniae Taiwan19F-14 7685359 YP_002742685.1 CDS SPT_1269 NC_012469.1 1206056 1207939 R identified by match to protein family HMM PF00753; match to protein family HMM PF01473; choline binding protein E complement(1206056..1207939) Streptococcus pneumoniae Taiwan19F-14 7685637 YP_002742686.1 CDS SPT_1270 NC_012469.1 1207942 1208829 R identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D (rRNA-uridine isomerase D) (rRNA pseudouridylate synthase D) complement(1207942..1208829) Streptococcus pneumoniae Taiwan19F-14 7686724 YP_002742687.1 CDS lspA NC_012469.1 1208819 1209280 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(1208819..1209280) Streptococcus pneumoniae Taiwan19F-14 7685261 YP_002742688.1 CDS SPT_1272 NC_012469.1 1209277 1210185 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; regulatory function on capsule expression in group B streptococci complement(1209277..1210185) Streptococcus pneumoniae Taiwan19F-14 7685388 YP_002742689.1 CDS SPT_1273 NC_012469.1 1210178 1210375 D hypothetical protein 1210178..1210375 Streptococcus pneumoniae Taiwan19F-14 7685330 YP_002742690.1 CDS SPT_1274 NC_012469.1 1210427 1211098 R identified by match to protein family HMM PF02517; caax amino protease family complement(1210427..1211098) Streptococcus pneumoniae Taiwan19F-14 7685941 YP_002742691.1 CDS SPT_1275 NC_012469.1 1211152 1211373 R identified by glimmer; putative; hypothetical protein complement(1211152..1211373) Streptococcus pneumoniae Taiwan19F-14 7686441 YP_002742692.1 CDS SPT_1276 NC_012469.1 1211645 1212454 D identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein 1211645..1212454 Streptococcus pneumoniae Taiwan19F-14 7685653 YP_002742693.1 CDS aguB NC_012469.1 1212635 1213510 R identified by match to protein family HMM PF00795; match to protein family HMM TIGR03381; N-carbamoylputrescine amidase complement(1212635..1213510) Streptococcus pneumoniae Taiwan19F-14 7686163 YP_002742694.1 CDS aguA NC_012469.1 1213520 1214605 R catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase complement(1213520..1214605) Streptococcus pneumoniae Taiwan19F-14 7686101 YP_002742695.1 CDS nspC NC_012469.1 1214602 1215729 R identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase complement(1214602..1215729) Streptococcus pneumoniae Taiwan19F-14 7685845 YP_002742696.1 CDS lys NC_012469.1 1215729 1216988 R identified by match to protein family HMM PF03435; saccharopine dehydrogenase complement(1215729..1216988) Streptococcus pneumoniae Taiwan19F-14 7686080 YP_002742697.1 CDS speE NC_012469.1 1216985 1217845 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(1216985..1217845) Streptococcus pneumoniae Taiwan19F-14 7686942 YP_002742698.1 CDS SPT_1282 NC_012469.1 1217876 1218013 R identified by glimmer; putative; hypothetical protein complement(1217876..1218013) Streptococcus pneumoniae Taiwan19F-14 7686250 YP_002742699.1 CDS SPT_1283 NC_012469.1 1218100 1218627 D an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1218100..1218627 Streptococcus pneumoniae Taiwan19F-14 7686342 YP_002742700.1 CDS SPT_1285 NC_012469.1 1218579 1218815 D an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 1218579..1218815 Streptococcus pneumoniae Taiwan19F-14 7687294 YP_002742701.1 CDS SPT_1284 NC_012469.1 1218781 1220256 R arginine decarboxylase complement(1218781..1220256) Streptococcus pneumoniae Taiwan19F-14 7686962 YP_002742702.1 CDS SPT_1286 NC_012469.1 1220963 1221838 D identified by match to protein family HMM PF00665; transposase 1220963..1221838 Streptococcus pneumoniae Taiwan19F-14 7686139 YP_002742703.1 CDS SPT_1287 NC_012469.1 1221984 1222412 D identified by match to protein family HMM PF01988; integral membrane protein 1221984..1222412 Streptococcus pneumoniae Taiwan19F-14 7686062 YP_002742704.1 CDS SPT_1288 NC_012469.1 1222455 1224443 R identified by match to protein family HMM PF02687; antimicrobial peptide ABC transporter permease complement(1222455..1224443) Streptococcus pneumoniae Taiwan19F-14 7685449 YP_002742705.1 CDS SPT_1289 NC_012469.1 1224445 1225203 R identified by match to protein family HMM PF00005; bacitracin export ATP-binding protein BceA complement(1224445..1225203) Streptococcus pneumoniae Taiwan19F-14 7686599 YP_002742706.1 CDS SPT_1290 NC_012469.1 1225632 1225823 D identified by glimmer; putative; hypothetical protein 1225632..1225823 Streptococcus pneumoniae Taiwan19F-14 7686323 YP_002742707.1 CDS SPT_1291 NC_012469.1 1226177 1226449 R identified by match to protein family HMM PF04024; PspC domain family complement(1226177..1226449) Streptococcus pneumoniae Taiwan19F-14 7686437 YP_002742708.1 CDS SPT_1292 NC_012469.1 1226508 1226957 R identified by match to protein family HMM PF03926; hypothetical protein complement(1226508..1226957) Streptococcus pneumoniae Taiwan19F-14 7685511 YP_002742709.1 CDS SPT_1293 NC_012469.1 1226944 1229073 R identified by match to protein family HMM PF00575; S1 RNA binding domain protein complement(1226944..1229073) Streptococcus pneumoniae Taiwan19F-14 7685875 YP_002742710.1 CDS SPT_1294 NC_012469.1 1229353 1229484 D identified by glimmer; putative; hypothetical protein 1229353..1229484 Streptococcus pneumoniae Taiwan19F-14 7687080 YP_002742711.1 CDS SPT_1295 NC_012469.1 1229485 1230390 D identified by match to protein family HMM PF03773; membrane protein 1229485..1230390 Streptococcus pneumoniae Taiwan19F-14 7686879 YP_002742712.1 CDS SPT_1296 NC_012469.1 1230387 1231202 D identified by match to protein family HMM PF09323; ABC transporter substrate-binding protein 1230387..1231202 Streptococcus pneumoniae Taiwan19F-14 7687070 YP_002742713.1 CDS SPT_1297 NC_012469.1 1231332 1232048 R hypothetical protein complement(1231332..1232048) Streptococcus pneumoniae Taiwan19F-14 7687274 YP_002742714.1 CDS SPT_1298 NC_012469.1 1232083 1232364 R identified by glimmer; putative; hypothetical protein complement(1232083..1232364) Streptococcus pneumoniae Taiwan19F-14 7685291 YP_002742715.1 CDS SPT_1299 NC_012469.1 1232507 1232890 D mobile genetic element 1232507..1232890 Streptococcus pneumoniae Taiwan19F-14 7687189 YP_002742716.1 CDS SPT_1300 NC_012469.1 1232997 1233869 R lipoprotein, putative complement(1232997..1233869) Streptococcus pneumoniae Taiwan19F-14 7686723 YP_002742717.1 CDS SPT_1301 NC_012469.1 1235381 1236727 D identified by match to protein family HMM PF01609; Spn1 transposase 1235381..1236727 Streptococcus pneumoniae Taiwan19F-14 7685856 YP_002742718.1 CDS pyk NC_012469.1 1237230 1238735 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1237230..1238735) Streptococcus pneumoniae Taiwan19F-14 7687251 YP_002742719.1 CDS pfkA NC_012469.1 1238794 1239801 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(1238794..1239801) Streptococcus pneumoniae Taiwan19F-14 7685730 YP_002742720.1 CDS dnaE NC_012469.1 1239884 1242985 R Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE complement(1239884..1242985) Streptococcus pneumoniae Taiwan19F-14 7685766 YP_002742721.1 CDS SPT_1305 NC_012469.1 1243332 1245605 D catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase 1243332..1245605 Streptococcus pneumoniae Taiwan19F-14 7685807 YP_002742722.1 CDS SPT_1306 NC_012469.1 1245622 1246092 D identified by match to protein family HMM PF01316; match to protein family HMM PF02863; arginine repressor 1245622..1246092 Streptococcus pneumoniae Taiwan19F-14 7685954 YP_002742723.1 CDS SPT_1307 NC_012469.1 1246209 1246364 R chlorohydrolase complement(1246209..1246364) Streptococcus pneumoniae Taiwan19F-14 7685349 YP_002742724.1 CDS SPT_1308 NC_012469.1 1246635 1249985 R identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; type I restriction-modification system R subunit complement(1246635..1249985) Streptococcus pneumoniae Taiwan19F-14 7687145 YP_002742725.1 CDS SPT_1309 NC_012469.1 1250015 1251058 R identified by match to protein family HMM PF01420; type I restriction-modification system, S subunit complement(1250015..1251058) Streptococcus pneumoniae Taiwan19F-14 7685374 YP_002742726.1 CDS SPT_1310 NC_012469.1 1251092 1252057 R identified by match to protein family HMM PF00589; match to protein family HMM PF02899; integrase/recombinase, phage integrase family complement(1251092..1252057) Streptococcus pneumoniae Taiwan19F-14 7685691 YP_002742727.1 CDS SPT_1311 NC_012469.1 1252175 1252588 R identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550; prophage maintenance system killer protein complement(1252175..1252588) Streptococcus pneumoniae Taiwan19F-14 7686187 YP_002742728.1 CDS SPT_1312 NC_012469.1 1252585 1252821 R hypothetical protein complement(1252585..1252821) Streptococcus pneumoniae Taiwan19F-14 7686176 YP_002742729.1 CDS SPT_1313 NC_012469.1 1252881 1254002 R identified by match to protein family HMM PF01420; type I restriction-modification system, S subunit, putative complement(1252881..1254002) Streptococcus pneumoniae Taiwan19F-14 7686257 YP_002742730.1 CDS SPT_1314 NC_012469.1 1254015 1255508 R identified by match to protein family HMM PF02384; type I restriction modification enzyme methylase subunit complement(1254015..1255508) Streptococcus pneumoniae Taiwan19F-14 7687385 YP_002742731.1 CDS SPT_1315 NC_012469.1 1255631 1255756 R identified by glimmer; putative; hypothetical protein complement(1255631..1255756) Streptococcus pneumoniae Taiwan19F-14 7687026 YP_002742732.1 CDS SPT_1316 NC_012469.1 1256016 1257182 R carbamoylphosphate synthase large subunit complement(1256016..1257182) Streptococcus pneumoniae Taiwan19F-14 7685659 YP_002742733.1 CDS SPT_1317 NC_012469.1 1257195 1257602 R identified by glimmer; putative; hypothetical protein complement(1257195..1257602) Streptococcus pneumoniae Taiwan19F-14 7686595 YP_002742734.1 CDS SPT_1318 NC_012469.1 1257599 1257934 R identified by glimmer; putative; hypothetical protein complement(1257599..1257934) Streptococcus pneumoniae Taiwan19F-14 7686439 YP_002742735.1 CDS SPT_1319 NC_012469.1 1257956 1258780 R identified by match to protein family HMM PF00756; putative esterase superfamily complement(1257956..1258780) Streptococcus pneumoniae Taiwan19F-14 7686540 YP_002742736.1 CDS thiI NC_012469.1 1258917 1260131 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(1258917..1260131) Streptococcus pneumoniae Taiwan19F-14 7686290 YP_002742737.1 CDS SPT_1321 NC_012469.1 1260140 1261282 R identified by match to protein family HMM PF00266; cysteine desulfurase complement(1260140..1261282) Streptococcus pneumoniae Taiwan19F-14 7686482 YP_002742738.1 CDS SPT_1322 NC_012469.1 1261420 1261848 D hypothetical protein 1261420..1261848 Streptococcus pneumoniae Taiwan19F-14 7687362 YP_002742739.1 CDS SPT_1323 NC_012469.1 1261892 1264117 R identified by match to protein family HMM PF01580; DNA translocase ftsk complement(1261892..1264117) Streptococcus pneumoniae Taiwan19F-14 7686641 YP_002742740.1 CDS fruA NC_012469.1 1264281 1266233 R identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; PTS system, fructose subfamily, IIABC component complement(1264281..1266233) Streptococcus pneumoniae Taiwan19F-14 7686255 YP_002742741.1 CDS pfkB NC_012469.1 1266230 1267141 R identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; 1-phosphofructokinase complement(1266230..1267141) Streptococcus pneumoniae Taiwan19F-14 7686128 YP_002742742.1 CDS SPT_1326 NC_012469.1 1267138 1267878 R identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; lactose phosphotransferase system repressor complement(1267138..1267878) Streptococcus pneumoniae Taiwan19F-14 7687099 YP_002742743.1 CDS SPT_1328 NC_012469.1 1269314 1270345 R identified by match to protein family HMM PF01594; membrane protein complement(1269314..1270345) Streptococcus pneumoniae Taiwan19F-14 7686581 YP_002742744.1 CDS SPT_1329 NC_012469.1 1270526 1271767 D identified by match to protein family HMM PF00144; match to protein family HMM PF00768; match to protein family HMM PF07943; penicillin-binding protein 3 1270526..1271767 Streptococcus pneumoniae Taiwan19F-14 7686808 YP_002742745.1 CDS sufB NC_012469.1 1271966 1273378 R identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980; FeS assembly protein SufB complement(1271966..1273378) Streptococcus pneumoniae Taiwan19F-14 7686398 YP_002742746.1 CDS SPT_1331 NC_012469.1 1273432 1273872 R identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994; SUF system FeS assembly protein, NifU family complement(1273432..1273872) Streptococcus pneumoniae Taiwan19F-14 7686719 YP_002742747.1 CDS SPT_1332 NC_012469.1 1273859 1275085 R identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979; cysteine desulfurase (Selenocysteine lyase) (Selenocysteine reductase) (Selenocysteine beta-lyase) (SCL) complement(1273859..1275085) Streptococcus pneumoniae Taiwan19F-14 7687014 YP_002742748.1 CDS sufD NC_012469.1 1275096 1276358 R identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981; FeS assembly protein SufD complement(1275096..1276358) Streptococcus pneumoniae Taiwan19F-14 7685692 YP_002742749.1 CDS sufC NC_012469.1 1276386 1277156 R identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; FeS assembly ATPase SufC complement(1276386..1277156) Streptococcus pneumoniae Taiwan19F-14 7685994 YP_002742750.1 CDS SPT_1335 NC_012469.1 1277306 1277428 R identified by match to protein family HMM PF01610; hypothetical protein complement(1277306..1277428) Streptococcus pneumoniae Taiwan19F-14 7687121 YP_002742751.1 CDS SPT_1336 NC_012469.1 1277528 1279183 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(1277528..1279183) Streptococcus pneumoniae Taiwan19F-14 7686522 YP_002742752.1 CDS SPT_1337 NC_012469.1 1279183 1279680 R GAF domain-containing protein complement(1279183..1279680) Streptococcus pneumoniae Taiwan19F-14 7685847 YP_002742753.1 CDS rpsA NC_012469.1 1281266 1282468 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(1281266..1282468) Streptococcus pneumoniae Taiwan19F-14 7685364 YP_002742754.1 CDS SPT_1343 NC_012469.1 1282841 1283071 R hypothetical protein complement(1282841..1283071) Streptococcus pneumoniae Taiwan19F-14 7685588 YP_002742755.1 CDS pcp1 NC_012469.1 1283239 1283883 R catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase complement(1283239..1283883) Streptococcus pneumoniae Taiwan19F-14 7687357 YP_002742756.1 CDS SPT_1345 NC_012469.1 1283898 1284821 R identified by match to protein family HMM PF06166; permease complement(1283898..1284821) Streptococcus pneumoniae Taiwan19F-14 7685830 YP_002742757.1 CDS SPT_1346 NC_012469.1 1284818 1285507 R identified by match to protein family HMM PF06149; permease complement(1284818..1285507) Streptococcus pneumoniae Taiwan19F-14 7686756 YP_002742758.1 CDS SPT_1347 NC_012469.1 1285572 1286276 R hypothetical protein complement(1285572..1286276) Streptococcus pneumoniae Taiwan19F-14 7685353 YP_002742759.1 CDS ilvE NC_012469.1 1286332 1287354 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(1286332..1287354) Streptococcus pneumoniae Taiwan19F-14 7686400 YP_002742760.1 CDS parC NC_012469.1 1287486 1289966 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(1287486..1289966) Streptococcus pneumoniae Taiwan19F-14 7685406 YP_002742761.1 CDS SPT_1350 NC_012469.1 1290131 1290256 R hypothetical protein complement(1290131..1290256) Streptococcus pneumoniae Taiwan19F-14 7686971 YP_002742762.1 CDS parE NC_012469.1 1290377 1292320 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(1290377..1292320) Streptococcus pneumoniae Taiwan19F-14 7686068 YP_002742763.1 CDS SPT_1352 NC_012469.1 1292456 1293097 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 1292456..1293097 Streptococcus pneumoniae Taiwan19F-14 7685813 YP_002742764.1 CDS SPT_1353 NC_012469.1 1293142 1293975 R identified by match to protein family HMM PF00665; integrase core domain protein complement(1293142..1293975) Streptococcus pneumoniae Taiwan19F-14 7686393 YP_002742765.1 CDS SPT_1355 NC_012469.1 1294498 1295454 R identified by match to protein family HMM PF02653; ribose/galactose ABC transporter permease complement(1294498..1295454) Streptococcus pneumoniae Taiwan19F-14 7685295 YP_002742766.1 CDS SPT_1356 NC_012469.1 1295457 1296515 R identified by match to protein family HMM PF02653; ribose/galactose ABC transporter permease complement(1295457..1296515) Streptococcus pneumoniae Taiwan19F-14 7687377 YP_002742767.1 CDS SPT_1357 NC_012469.1 1296508 1298043 R identified by match to protein family HMM PF00005; ribose import ATP-binding protein RbsA complement(1296508..1298043) Streptococcus pneumoniae Taiwan19F-14 7685398 YP_002742768.1 CDS SPT_1358 NC_012469.1 1298187 1299239 R identified by match to protein family HMM PF02608; lipoprotein complement(1298187..1299239) Streptococcus pneumoniae Taiwan19F-14 7685301 YP_002742769.1 CDS cdd NC_012469.1 1299330 1299719 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(1299330..1299719) Streptococcus pneumoniae Taiwan19F-14 7686729 YP_002742770.1 CDS deoC NC_012469.1 1299706 1300368 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(1299706..1300368) Streptococcus pneumoniae Taiwan19F-14 7685258 YP_002742771.1 CDS SPT_1361 NC_012469.1 1300386 1301663 R Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase complement(1300386..1301663) Streptococcus pneumoniae Taiwan19F-14 7686447 YP_002742772.1 CDS SPT_1362 NC_012469.1 1301660 1302241 R identified by match to protein family HMM PF05175; methyltransferase small domain superfamily complement(1301660..1302241) Streptococcus pneumoniae Taiwan19F-14 7686584 YP_002742773.1 CDS SPT_1363 NC_012469.1 1302624 1302860 R identified by glimmer; putative; hypothetical protein complement(1302624..1302860) Streptococcus pneumoniae Taiwan19F-14 7686676 YP_002742774.1 CDS coaA NC_012469.1 1303050 1303970 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 1303050..1303970 Streptococcus pneumoniae Taiwan19F-14 7686122 YP_002742775.1 CDS rpsT NC_012469.1 1304038 1304274 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1304038..1304274 Streptococcus pneumoniae Taiwan19F-14 7686047 YP_002742776.1 CDS SPT_1366 NC_012469.1 1304327 1304851 D topology modulation protein 1304327..1304851 Streptococcus pneumoniae Taiwan19F-14 7686700 YP_002742777.1 CDS deoD NC_012469.1 1304874 1305584 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(1304874..1305584) Streptococcus pneumoniae Taiwan19F-14 7686653 YP_002742778.1 CDS SPT_1368 NC_012469.1 1306242 1306754 R hemolysin-related protein complement(1306242..1306754) Streptococcus pneumoniae Taiwan19F-14 7685386 YP_002742779.1 CDS SPT_1369 NC_012469.1 1306779 1307354 R identified by glimmer; putative; hypothetical protein complement(1306779..1307354) Streptococcus pneumoniae Taiwan19F-14 7686132 YP_002742780.1 CDS SPT_1370 NC_012469.1 1307364 1307771 R identified by glimmer; putative; hypothetical protein complement(1307364..1307771) Streptococcus pneumoniae Taiwan19F-14 7685315 YP_002742781.1 CDS SPT_1371 NC_012469.1 1308235 1309044 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(1308235..1309044) Streptococcus pneumoniae Taiwan19F-14 7687285 YP_002742782.1 CDS SPT_1372 NC_012469.1 1309060 1309602 R identified by match to protein family HMM PF08002; hypothetical protein complement(1309060..1309602) Streptococcus pneumoniae Taiwan19F-14 7685855 YP_002742783.1 CDS deoB NC_012469.1 1309604 1310815 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1309604..1310815) Streptococcus pneumoniae Taiwan19F-14 7686167 YP_002742784.1 CDS rpiA NC_012469.1 1310829 1311512 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(1310829..1311512) Streptococcus pneumoniae Taiwan19F-14 7685746 YP_002742785.1 CDS SPT_1375 NC_012469.1 1311794 1312666 R identified by match to protein family HMM PF01256; match to protein family HMM TIGR00196; putative YjeF homolog, C-terminus complement(1311794..1312666) Streptococcus pneumoniae Taiwan19F-14 7686533 YP_002742786.1 CDS SPT_1376 NC_012469.1 1312808 1313686 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(1312808..1313686) Streptococcus pneumoniae Taiwan19F-14 7685823 YP_002742787.1 CDS SPT_1377 NC_012469.1 1313819 1314553 R identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ complement(1313819..1314553) Streptococcus pneumoniae Taiwan19F-14 7686824 YP_002742788.1 CDS SPT_1378 NC_012469.1 1314553 1315182 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease complement(1314553..1315182) Streptococcus pneumoniae Taiwan19F-14 7686030 YP_002742789.1 CDS SPT_1379 NC_012469.1 1315424 1315654 D identified by match to protein family HMM PF08796; hypothetical protein 1315424..1315654 Streptococcus pneumoniae Taiwan19F-14 7685914 YP_002742790.1 CDS SPT_1380 NC_012469.1 1315883 1318141 D identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF07724; match to protein family HMM PF07728; negative regulator of genetic competence ClpC/mecB 1315883..1318141 Streptococcus pneumoniae Taiwan19F-14 7687122 YP_002742791.1 CDS SPT_1381 NC_012469.1 1318600 1318848 D hypothetical protein 1318600..1318848 Streptococcus pneumoniae Taiwan19F-14 7686917 YP_002742792.1 CDS SPT_1382 NC_012469.1 1318887 1319216 R identified by match to protein family HMM PF01710; transposase complement(1318887..1319216) Streptococcus pneumoniae Taiwan19F-14 7687182 YP_002742793.1 CDS SPT_1383 NC_012469.1 1319486 1319749 D identified by glimmer; putative; hypothetical protein 1319486..1319749 Streptococcus pneumoniae Taiwan19F-14 7686317 YP_002742794.1 CDS SPT_1384 NC_012469.1 1319914 1320213 D identified by match to protein family HMM PF08860; hypothetical protein 1319914..1320213 Streptococcus pneumoniae Taiwan19F-14 7686476 YP_002742795.1 CDS SPT_1385 NC_012469.1 1320322 1321155 R identified by match to protein family HMM PF00665; integrase core domain protein complement(1320322..1321155) Streptococcus pneumoniae Taiwan19F-14 7687287 YP_002742796.1 CDS SPT_1386 NC_012469.1 1321155 1321277 R identified by glimmer; putative; hypothetical protein complement(1321155..1321277) Streptococcus pneumoniae Taiwan19F-14 7686622 YP_002742797.1 CDS SPT_1388 NC_012469.1 1321835 1322185 D identified by match to protein family HMM PF05717; transposase 1321835..1322185 Streptococcus pneumoniae Taiwan19F-14 7687226 YP_002742798.1 CDS ezrA NC_012469.1 1323986 1325713 R acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA complement(1323986..1325713) Streptococcus pneumoniae Taiwan19F-14 7685982 YP_002742799.1 CDS gyrB NC_012469.1 1325795 1327741 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(1325795..1327741) Streptococcus pneumoniae Taiwan19F-14 7685715 YP_002742800.1 CDS SPT_1394 NC_012469.1 1327756 1328319 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; phosphoglycolate phosphatase complement(1327756..1328319) Streptococcus pneumoniae Taiwan19F-14 7685891 YP_002742801.1 CDS SPT_1395 NC_012469.1 1328404 1328958 R identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383; putative 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein complement(1328404..1328958) Streptococcus pneumoniae Taiwan19F-14 7686563 YP_002742802.1 CDS SPT_1396 NC_012469.1 1328969 1330192 R identified by match to protein family HMM PF01098; RodA complement(1328969..1330192) Streptococcus pneumoniae Taiwan19F-14 7686827 YP_002742803.1 CDS SPT_1397 NC_012469.1 1330229 1332679 R unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon complement(1330229..1332679) Streptococcus pneumoniae Taiwan19F-14 7686087 YP_002742804.1 CDS SPT_1398 NC_012469.1 1332879 1333808 R identified by match to protein family HMM PF01136; protease complement(1332879..1333808) Streptococcus pneumoniae Taiwan19F-14 7685992 YP_002742805.1 CDS SPT_1399 NC_012469.1 1333948 1334235 D hypothetical protein 1333948..1334235 Streptococcus pneumoniae Taiwan19F-14 7686348 YP_002742806.1 CDS SPT_1400 NC_012469.1 1334269 1335603 R identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor protein CiaH complement(1334269..1335603) Streptococcus pneumoniae Taiwan19F-14 7686994 YP_002742807.1 CDS SPT_1401 NC_012469.1 1335593 1336267 R identified by match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein CiaR complement(1335593..1336267) Streptococcus pneumoniae Taiwan19F-14 7686960 YP_002742808.1 CDS SPT_1402 NC_012469.1 1336376 1338922 R identified by match to protein family HMM PF01433; aminopeptidase N complement(1336376..1338922) Streptococcus pneumoniae Taiwan19F-14 7687292 YP_002742809.1 CDS SPT_1403 NC_012469.1 1339045 1339485 R identified by match to protein family HMM PF06171; hypothetical protein complement(1339045..1339485) Streptococcus pneumoniae Taiwan19F-14 7687162 YP_002742810.1 CDS SPT_1404 NC_012469.1 1339460 1340329 R identified by match to protein family HMM PF02896; PEP-utilizing enzyme family protein complement(1339460..1340329) Streptococcus pneumoniae Taiwan19F-14 7686457 YP_002742811.1 CDS SPT_1405 NC_012469.1 1340307 1340807 R identified by match to protein family HMM PF00293; MutT/nudix family protein complement(1340307..1340807) Streptococcus pneumoniae Taiwan19F-14 7686201 YP_002742812.1 CDS fabG NC_012469.1 1340818 1341516 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1340818..1341516) Streptococcus pneumoniae Taiwan19F-14 7685495 YP_002742813.1 CDS SPT_1407 NC_012469.1 1341509 1341745 R hypothetical protein complement(1341509..1341745) Streptococcus pneumoniae Taiwan19F-14 7685673 YP_002742814.1 CDS SPT_1408 NC_012469.1 1341841 1342767 R identified by match to protein family HMM PF00248; oxidoreductase, aldo/keto reductase family complement(1341841..1342767) Streptococcus pneumoniae Taiwan19F-14 7685403 YP_002742815.1 CDS SPT_1409 NC_012469.1 1342842 1343657 R hypothetical protein complement(1342842..1343657) Streptococcus pneumoniae Taiwan19F-14 7685264 YP_002742816.1 CDS SPT_1410 NC_012469.1 1343661 1343981 R identified by match to protein family HMM PF03551; transcriptional regulator, PadR family complement(1343661..1343981) Streptococcus pneumoniae Taiwan19F-14 7685356 YP_002742817.1 CDS SPT_1411 NC_012469.1 1344071 1344532 R hypothetical protein complement(1344071..1344532) Streptococcus pneumoniae Taiwan19F-14 7685812 YP_002742818.1 CDS metG NC_012469.1 1344582 1346579 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1344582..1346579) Streptococcus pneumoniae Taiwan19F-14 7686742 YP_002742819.1 CDS SPT_1413 NC_012469.1 1346703 1347962 R identified by match to protein family HMM PF02687; antimicrobial peptide ABC transporter permease complement(1346703..1347962) Streptococcus pneumoniae Taiwan19F-14 7687322 YP_002742820.1 CDS SPT_1414 NC_012469.1 1347964 1348665 R identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB complement(1347964..1348665) Streptococcus pneumoniae Taiwan19F-14 7686878 YP_002742821.1 CDS SPT_1415 NC_012469.1 1348649 1349848 R identified by match to protein family HMM TIGR01730; membrane-fusion protein complement(1348649..1349848) Streptococcus pneumoniae Taiwan19F-14 7685974 YP_002742822.1 CDS gor NC_012469.1 1350134 1351480 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 1350134..1351480 Streptococcus pneumoniae Taiwan19F-14 7685865 YP_002742823.1 CDS SPT_1417 NC_012469.1 1351677 1352213 D identified by match to protein family HMM PF02632; biotin synthase 1351677..1352213 Streptococcus pneumoniae Taiwan19F-14 7686445 YP_002742824.1 CDS SPT_1419 NC_012469.1 1352276 1352422 D chlorohydrolase 1352276..1352422 Streptococcus pneumoniae Taiwan19F-14 7686120 YP_002742825.1 CDS SPT_1418 NC_012469.1 1352419 1352634 R hypothetical protein complement(1352419..1352634) Streptococcus pneumoniae Taiwan19F-14 7685700 YP_002742826.1 CDS SPT_1420 NC_012469.1 1352732 1353052 D hypothetical protein 1352732..1353052 Streptococcus pneumoniae Taiwan19F-14 7686686 YP_002742827.1 CDS SPT_1421 NC_012469.1 1353082 1353420 R identified by match to protein family HMM PF03477; oxygen-sensitive ribonucleoside-triphosphate reductase complement(1353082..1353420) Streptococcus pneumoniae Taiwan19F-14 7686683 YP_002742828.1 CDS trmD NC_012469.1 1353432 1354151 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1353432..1354151) Streptococcus pneumoniae Taiwan19F-14 7686152 YP_002742829.1 CDS rimM NC_012469.1 1354141 1354659 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1354141..1354659) Streptococcus pneumoniae Taiwan19F-14 7687395 YP_002742830.1 CDS SPT_1424 NC_012469.1 1354690 1355478 R identified by match to protein family HMM PF00561; hydrolase, alpha/beta fold family, putative complement(1354690..1355478) Streptococcus pneumoniae Taiwan19F-14 7685304 YP_002742831.1 CDS SPT_1425 NC_012469.1 1356025 1357371 D identified by match to protein family HMM PF01609; Spn1 transposase 1356025..1357371 Streptococcus pneumoniae Taiwan19F-14 7686395 YP_002742832.1 CDS tuf NC_012469.1 1357832 1359028 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1357832..1359028) Streptococcus pneumoniae Taiwan19F-14 7685530 YP_002742833.1 CDS SPT_1427 NC_012469.1 1359371 1359493 R hypothetical protein complement(1359371..1359493) Streptococcus pneumoniae Taiwan19F-14 7687283 YP_002742834.1 CDS SPT_1428 NC_012469.1 1359939 1360808 R identified by match to protein family HMM PF00230; glycerol facilitator-aquaporin gla (Aquaglyceroporin)(Glyceroaquaporin) complement(1359939..1360808) Streptococcus pneumoniae Taiwan19F-14 7686490 YP_002742835.1 CDS SPT_1429 NC_012469.1 1361031 1361552 R identified by match to protein family HMM PF00746; match to protein family HMM PF06458; match to protein family HMM TIGR01167; MucBP domain family complement(1361031..1361552) Streptococcus pneumoniae Taiwan19F-14 7687009 YP_002742836.1 CDS SPT_1430 NC_012469.1 1361524 1362615 R identified by glimmer; putative; hypothetical protein complement(1361524..1362615) Streptococcus pneumoniae Taiwan19F-14 7685526 YP_002742837.1 CDS SPT_1431 NC_012469.1 1362726 1362980 R hypothetical protein complement(1362726..1362980) Streptococcus pneumoniae Taiwan19F-14 7686970 YP_002742838.1 CDS SPT_1432 NC_012469.1 1363320 1363853 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase complement(1363320..1363853) Streptococcus pneumoniae Taiwan19F-14 7687216 YP_002742839.1 CDS SPT_1433 NC_012469.1 1363840 1363974 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase complement(1363840..1363974) Streptococcus pneumoniae Taiwan19F-14 7686272 YP_002742840.1 CDS SPT_1434 NC_012469.1 1364022 1364165 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase complement(1364022..1364165) Streptococcus pneumoniae Taiwan19F-14 7686265 YP_002742841.1 CDS SPT_1435 NC_012469.1 1364399 1366117 D identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 1364399..1366117 Streptococcus pneumoniae Taiwan19F-14 7685433 YP_002742842.1 CDS SPT_1436 NC_012469.1 1366228 1366575 D identified by match to protein family HMM TIGR01295; bacterocin transport accessory protein 1366228..1366575 Streptococcus pneumoniae Taiwan19F-14 7686415 YP_002742843.1 CDS SPT_1437 NC_012469.1 1366854 1367690 R identified by match to protein family HMM PF00497; ABC transporter substrate-binding protein - glutamine transport complement(1366854..1367690) Streptococcus pneumoniae Taiwan19F-14 7686912 YP_002742844.1 CDS SPT_1438 NC_012469.1 1367703 1368332 R identified by match to protein family HMM PF00005; glutamine transport ATP-binding protein GlnQ complement(1367703..1368332) Streptococcus pneumoniae Taiwan19F-14 7686146 YP_002742845.1 CDS SPT_1439 NC_012469.1 1368342 1368983 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease complement(1368342..1368983) Streptococcus pneumoniae Taiwan19F-14 7686873 YP_002742846.1 CDS SPT_1440 NC_012469.1 1369129 1370358 R identified by match to protein family HMM PF00515; match to protein family HMM PF07719; TPR domain protein complement(1369129..1370358) Streptococcus pneumoniae Taiwan19F-14 7687169 YP_002742847.1 CDS SPT_1441 NC_012469.1 1370348 1371514 R identified by match to protein family HMM PF01594; transport protein complement(1370348..1371514) Streptococcus pneumoniae Taiwan19F-14 7685358 YP_002742848.1 CDS SPT_1442 NC_012469.1 1371658 1372671 D 3-carboxymuconate cyclase 1371658..1372671 Streptococcus pneumoniae Taiwan19F-14 7686951 YP_002742849.1 CDS atpC NC_012469.1 1372716 1373135 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1372716..1373135) Streptococcus pneumoniae Taiwan19F-14 7686088 YP_002742850.1 CDS atpD NC_012469.1 1373146 1374552 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1373146..1374552) Streptococcus pneumoniae Taiwan19F-14 7686277 YP_002742851.1 CDS atpG NC_012469.1 1374638 1375516 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1374638..1375516) Streptococcus pneumoniae Taiwan19F-14 7687228 YP_002742852.1 CDS atpA NC_012469.1 1375532 1377037 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1375532..1377037) Streptococcus pneumoniae Taiwan19F-14 7685872 YP_002742853.1 CDS atpH NC_012469.1 1377052 1377588 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1377052..1377588) Streptococcus pneumoniae Taiwan19F-14 7685972 YP_002742854.1 CDS atpF NC_012469.1 1377588 1378082 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1377588..1378082) Streptococcus pneumoniae Taiwan19F-14 7685893 YP_002742855.1 CDS atpB NC_012469.1 1378096 1378812 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1378096..1378812) Streptococcus pneumoniae Taiwan19F-14 7686751 YP_002742856.1 CDS SPT_1450 NC_012469.1 1378847 1379047 R produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1378847..1379047) Streptococcus pneumoniae Taiwan19F-14 7685413 YP_002742857.1 CDS SPT_1453 NC_012469.1 1380585 1380983 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family protein complement(1380585..1380983) Streptococcus pneumoniae Taiwan19F-14 7685757 YP_002742858.1 CDS SPT_1454 NC_012469.1 1381111 1381254 D chlorohydrolase 1381111..1381254 Streptococcus pneumoniae Taiwan19F-14 7687257 YP_002742859.1 CDS greA NC_012469.1 1381311 1381793 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1381311..1381793) Streptococcus pneumoniae Taiwan19F-14 7686708 YP_002742860.1 CDS SPT_1456 NC_012469.1 1381864 1383519 R identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247; aminodeoxychorismate lyase complement(1381864..1383519) Streptococcus pneumoniae Taiwan19F-14 7685634 YP_002742861.1 CDS SPT_1457 NC_012469.1 1383600 1384094 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family complement(1383600..1384094) Streptococcus pneumoniae Taiwan19F-14 7685702 YP_002742862.1 CDS SPT_1458 NC_012469.1 1384091 1384555 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family complement(1384091..1384555) Streptococcus pneumoniae Taiwan19F-14 7685253 YP_002742863.1 CDS murC NC_012469.1 1384565 1385899 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1384565..1385899) Streptococcus pneumoniae Taiwan19F-14 7685394 YP_002742864.1 CDS SPT_1460 NC_012469.1 1385910 1386527 R hypothetical protein complement(1385910..1386527) Streptococcus pneumoniae Taiwan19F-14 7686807 YP_002742865.1 CDS SPT_1461 NC_012469.1 1386575 1389673 R identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434; match to protein family HMM PF08455; Snf2 family protein complement(1386575..1389673) Streptococcus pneumoniae Taiwan19F-14 7685334 YP_002742866.1 CDS SPT_1462 NC_012469.1 1389766 1390932 R identified by match to protein family HMM PF00155; putative aminotransferase B complement(1389766..1390932) Streptococcus pneumoniae Taiwan19F-14 7687355 YP_002742867.1 CDS SPT_1463 NC_012469.1 1390940 1392034 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(1390940..1392034) Streptococcus pneumoniae Taiwan19F-14 7685619 YP_002742868.1 CDS SPT_1466 NC_012469.1 1394045 1396006 R identified by match to protein family HMM PF00496; oligopeptide-binding protein AliB complement(1394045..1396006) Streptococcus pneumoniae Taiwan19F-14 7687174 YP_002742869.1 CDS SPT_1467 NC_012469.1 1396207 1397829 R identified by match to protein family HMM PF01943; match to protein family HMM PF03023; polysaccharide transporter complement(1396207..1397829) Streptococcus pneumoniae Taiwan19F-14 7687302 YP_002742870.1 CDS SPT_1468 NC_012469.1 1397935 1399380 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1397935..1399380 Streptococcus pneumoniae Taiwan19F-14 7686405 YP_002742871.1 CDS SPT_1469 NC_012469.1 1399426 1399620 R identified by match to protein family HMM PF05532; hypothetical protein complement(1399426..1399620) Streptococcus pneumoniae Taiwan19F-14 7686611 YP_002742872.1 CDS SPT_1470 NC_012469.1 1399721 1400317 R identified by glimmer; putative; hypothetical protein complement(1399721..1400317) Streptococcus pneumoniae Taiwan19F-14 7685279 YP_002742873.1 CDS SPT_1471 NC_012469.1 1400354 1400866 R hypothetical protein complement(1400354..1400866) Streptococcus pneumoniae Taiwan19F-14 7687187 YP_002742874.1 CDS SPT_1472 NC_012469.1 1400953 1401888 R catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase complement(1400953..1401888) Streptococcus pneumoniae Taiwan19F-14 7686491 YP_002742875.1 CDS SPT_1473 NC_012469.1 1401959 1402258 R identified by match to protein family HMM PF01541; hypothetical protein complement(1401959..1402258) Streptococcus pneumoniae Taiwan19F-14 7686206 YP_002742876.1 CDS SPT_1474 NC_012469.1 1402248 1402997 R identified by match to protein family HMM PF05175; methyltransferase complement(1402248..1402997) Streptococcus pneumoniae Taiwan19F-14 7685501 YP_002742877.1 CDS SPT_1475 NC_012469.1 1403051 1403437 R identified by match to protein family HMM PF00575; hypothetical protein complement(1403051..1403437) Streptococcus pneumoniae Taiwan19F-14 7686887 YP_002742878.1 CDS SPT_1476 NC_012469.1 1403412 1404812 R identified by match to protein family HMM PF00160; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type complement(1403412..1404812) Streptococcus pneumoniae Taiwan19F-14 7686701 YP_002742879.1 CDS rpsR NC_012469.1 1405107 1405346 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1405107..1405346) Streptococcus pneumoniae Taiwan19F-14 7687299 YP_002742880.1 CDS SPT_1478 NC_012469.1 1405378 1405848 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1405378..1405848) Streptococcus pneumoniae Taiwan19F-14 7687063 YP_002742881.1 CDS rpsF NC_012469.1 1405860 1406150 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1405860..1406150) Streptococcus pneumoniae Taiwan19F-14 7686307 YP_002742882.1 CDS asnC NC_012469.1 1406303 1407646 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1406303..1407646) Streptococcus pneumoniae Taiwan19F-14 7685333 YP_002742883.1 CDS SPT_1481 NC_012469.1 1407806 1408030 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; glyoxalase family protein, unverified point mutation complement(1407806..1408030) Streptococcus pneumoniae Taiwan19F-14 7686142 YP_002742884.1 CDS SPT_1482 NC_012469.1 1408023 1409210 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(1408023..1409210) Streptococcus pneumoniae Taiwan19F-14 7686841 YP_002742885.1 CDS SPT_1483 NC_012469.1 1409207 1409695 R identified by match to protein family HMM PF03413; peptidase propeptide and ypeb domain protein complement(1409207..1409695) Streptococcus pneumoniae Taiwan19F-14 7687093 YP_002742886.1 CDS SPT_1484 NC_012469.1 1409762 1409878 R identified by glimmer; putative; hypothetical protein complement(1409762..1409878) Streptococcus pneumoniae Taiwan19F-14 7686803 YP_002742887.1 CDS SPT_1485 NC_012469.1 1410016 1410564 D identified by match to protein family HMM PF02525; match to protein family HMM PF03358; oxidoreductase 1410016..1410564 Streptococcus pneumoniae Taiwan19F-14 7685305 YP_002742888.1 CDS SPT_1486 NC_012469.1 1410801 1416422 R identified by match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; G5 domain family complement(1410801..1416422) Streptococcus pneumoniae Taiwan19F-14 7685250 YP_002742889.1 CDS SPT_1487 NC_012469.1 1416638 1418122 D identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280; M protein trans-acting positive transcriptional regulator 1416638..1418122 Streptococcus pneumoniae Taiwan19F-14 7685365 YP_002742890.1 CDS SPT_1488 NC_012469.1 1418173 1418901 R identified by match to protein family HMM PF03883; hypothetical protein complement(1418173..1418901) Streptococcus pneumoniae Taiwan19F-14 7686541 YP_002742891.1 CDS SPT_1489 NC_012469.1 1418980 1419144 R hypothetical protein complement(1418980..1419144) Streptococcus pneumoniae Taiwan19F-14 7687300 YP_002742892.1 CDS SPT_1490 NC_012469.1 1419210 1420805 R hypothetical protein complement(1419210..1420805) Streptococcus pneumoniae Taiwan19F-14 7686796 YP_002742893.1 CDS def2 NC_012469.1 1420817 1421227 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1420817..1421227) Streptococcus pneumoniae Taiwan19F-14 7685290 YP_002742894.1 CDS SPT_1492 NC_012469.1 1421343 1422134 R YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU complement(1421343..1422134) Streptococcus pneumoniae Taiwan19F-14 7685421 YP_002742895.1 CDS SPT_1493 NC_012469.1 1422147 1424843 R identified by match to protein family HMM PF00122; match to protein family HMM PF00689; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; calcium-transporting ATPase 1 complement(1422147..1424843) Streptococcus pneumoniae Taiwan19F-14 7685661 YP_002742896.1 CDS SPT_1494 NC_012469.1 1425147 1426331 D identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1425147..1426331 Streptococcus pneumoniae Taiwan19F-14 7685316 YP_002742897.1 CDS SPT_1495 NC_012469.1 1426474 1428345 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1426474..1428345) Streptococcus pneumoniae Taiwan19F-14 7686812 YP_002742898.1 CDS SPT_1496 NC_012469.1 1428342 1429526 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(1428342..1429526) Streptococcus pneumoniae Taiwan19F-14 7686950 YP_002742899.1 CDS dapB NC_012469.1 1429538 1430305 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(1429538..1430305) Streptococcus pneumoniae Taiwan19F-14 7685966 YP_002742900.1 CDS SPT_1498 NC_012469.1 1430582 1431430 R identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein complement(1430582..1431430) Streptococcus pneumoniae Taiwan19F-14 7686902 YP_002742901.1 CDS SPT_1499 NC_012469.1 1431432 1431806 R identified by match to protein family HMM PF06619; hypothetical protein complement(1431432..1431806) Streptococcus pneumoniae Taiwan19F-14 7686409 YP_002742902.1 CDS glmM NC_012469.1 1431880 1433232 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1431880..1433232) Streptococcus pneumoniae Taiwan19F-14 7685729 YP_002742903.1 CDS SPT_1501 NC_012469.1 1433256 1434035 R identified by match to protein family HMM PF07949; lipoprotein, putative complement(1433256..1434035) Streptococcus pneumoniae Taiwan19F-14 7687242 YP_002742904.1 CDS SPT_1502 NC_012469.1 1434022 1434879 R identified by match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein complement(1434022..1434879) Streptococcus pneumoniae Taiwan19F-14 7685452 YP_002742905.1 CDS SPT_1503 NC_012469.1 1435015 1435983 D identified by match to protein family HMM PF00070; match to protein family HMM PF03486; match to protein family HMM PF07992; thioredoxin reductase 1435015..1435983 Streptococcus pneumoniae Taiwan19F-14 7686835 YP_002742906.1 CDS SPT_1504 NC_012469.1 1436017 1436928 R identified by match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein complement(1436017..1436928) Streptococcus pneumoniae Taiwan19F-14 7685418 YP_002742907.1 CDS SPT_1505 NC_012469.1 1436925 1437902 R identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826; transporter complement(1436925..1437902) Streptococcus pneumoniae Taiwan19F-14 7685678 YP_002742908.1 CDS SPT_1506 NC_012469.1 1437899 1438789 R identified by match to protein family HMM PF03668; hypothetical protein complement(1437899..1438789) Streptococcus pneumoniae Taiwan19F-14 7686818 YP_002742909.1 CDS SPT_1507 NC_012469.1 1438841 1439221 R identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP, putative complement(1438841..1439221) Streptococcus pneumoniae Taiwan19F-14 7685319 YP_002742910.1 CDS engB NC_012469.1 1439232 1439819 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1439232..1439819) Streptococcus pneumoniae Taiwan19F-14 7686768 YP_002742911.1 CDS clpX NC_012469.1 1439828 1441036 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1439828..1441036) Streptococcus pneumoniae Taiwan19F-14 7685876 YP_002742912.1 CDS SPT_1510 NC_012469.1 1441097 1441267 R hypothetical protein complement(1441097..1441267) Streptococcus pneumoniae Taiwan19F-14 7686549 YP_002742913.1 CDS folA NC_012469.1 1441267 1441773 R identified by match to protein family HMM PF00186; dihydrofolate reductase complement(1441267..1441773) Streptococcus pneumoniae Taiwan19F-14 7685846 YP_002742914.1 CDS SPT_1512 NC_012469.1 1441903 1442421 R identified by match to protein family HMM PF00210; DNA protection during starvation protein complement(1441903..1442421) Streptococcus pneumoniae Taiwan19F-14 7685517 YP_002742915.1 CDS SPT_1513 NC_012469.1 1442921 1444402 R identified by match to protein family HMM PF01183; match to protein family HMM PF01473; lysozyme complement(1442921..1444402) Streptococcus pneumoniae Taiwan19F-14 7686966 YP_002742916.1 CDS tpiA NC_012469.1 1444473 1445231 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1444473..1445231) Streptococcus pneumoniae Taiwan19F-14 7687089 YP_002742917.1 CDS SPT_1515 NC_012469.1 1445329 1446006 R identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446; DNA replication protein DnaD complement(1445329..1446006) Streptococcus pneumoniae Taiwan19F-14 7686848 YP_002742918.1 CDS metA NC_012469.1 1446015 1446959 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(1446015..1446959) Streptococcus pneumoniae Taiwan19F-14 7687135 YP_002742919.1 CDS SPT_1518 NC_012469.1 1446999 1447250 D identified by glimmer; putative; hypothetical protein 1446999..1447250 Streptococcus pneumoniae Taiwan19F-14 7685422 YP_002742920.1 CDS apt NC_012469.1 1447247 1447759 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1447247..1447759) Streptococcus pneumoniae Taiwan19F-14 7685354 YP_002742921.1 CDS SPT_1519 NC_012469.1 1447845 1448603 R identified by match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase complement(1447845..1448603) Streptococcus pneumoniae Taiwan19F-14 7685644 YP_002742922.1 CDS SPT_1520 NC_012469.1 1449104 1450234 R identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; multiple sugar-binding transport ATP-binding protein MsmK complement(1449104..1450234) Streptococcus pneumoniae Taiwan19F-14 7686645 YP_002742923.1 CDS SPT_1522 NC_012469.1 1450685 1451260 R identified by match to protein family HMM PF00857; isochorismatase complement(1450685..1451260) Streptococcus pneumoniae Taiwan19F-14 7685579 YP_002742924.1 CDS codY NC_012469.1 1451260 1452048 R CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY complement(1451260..1452048) Streptococcus pneumoniae Taiwan19F-14 7686158 YP_002742925.1 CDS SPT_1524 NC_012469.1 1452313 1453887 R identified by match to protein family HMM PF00270; match to protein family HMM PF00271; cold-shock DEAD box protein A complement(1452313..1453887) Streptococcus pneumoniae Taiwan19F-14 7687157 YP_002742926.1 CDS SPT_1525 NC_012469.1 1454086 1455312 R identified by match to protein family HMM PF07690; major facilitator:Oxalate:Formate Antiporter complement(1454086..1455312) Streptococcus pneumoniae Taiwan19F-14 7686619 YP_002742927.1 CDS SPT_1526 NC_012469.1 1455505 1456821 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1455505..1456821 Streptococcus pneumoniae Taiwan19F-14 7687119 YP_002742928.1 CDS SPT_1527 NC_012469.1 1456920 1458263 D identified by match to protein family HMM PF08245; match to protein family HMM PF08353; Mur ligase family protein 1456920..1458263 Streptococcus pneumoniae Taiwan19F-14 7686855 YP_002742929.1 CDS SPT_1528 NC_012469.1 1458263 1459045 D identified by match to protein family HMM PF07685; cobyric acid synthase 1458263..1459045 Streptococcus pneumoniae Taiwan19F-14 7687112 YP_002742930.1 CDS SPT_1529 NC_012469.1 1459171 1460253 D identified by match to protein family HMM PF00557; match to protein family HMM PF01321; Xaa-Pro dipeptidase (X-Pro dipeptidase) (Prolinedipeptidase) (Prolidase) (Imidodipeptidase) 1459171..1460253 Streptococcus pneumoniae Taiwan19F-14 7686996 YP_002742931.1 CDS SPT_1530 NC_012469.1 1460303 1460449 D acetyltransferase, gnat family 1460303..1460449 Streptococcus pneumoniae Taiwan19F-14 7686253 YP_002742932.1 CDS SPT_1531 NC_012469.1 1460577 1460930 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase complement(1460577..1460930) Streptococcus pneumoniae Taiwan19F-14 7687234 YP_002742933.1 CDS SPT_1532 NC_012469.1 1460992 1461264 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase complement(1460992..1461264) Streptococcus pneumoniae Taiwan19F-14 7686300 YP_002742934.1 CDS SPT_1533 NC_012469.1 1461264 1461431 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase complement(1461264..1461431) Streptococcus pneumoniae Taiwan19F-14 7686097 YP_002742935.1 CDS SPT_1534 NC_012469.1 1461567 1461779 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase complement(1461567..1461779) Streptococcus pneumoniae Taiwan19F-14 7686907 YP_002742936.1 CDS SPT_1535 NC_012469.1 1462010 1462471 R hypothetical protein complement(1462010..1462471) Streptococcus pneumoniae Taiwan19F-14 7685456 YP_002742937.1 CDS SPT_1536 NC_012469.1 1462449 1463222 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(1462449..1463222) Streptococcus pneumoniae Taiwan19F-14 7685927 YP_002742938.1 CDS truA NC_012469.1 1463212 1463961 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1463212..1463961) Streptococcus pneumoniae Taiwan19F-14 7685493 YP_002742939.1 CDS SPT_1539 NC_012469.1 1464140 1464301 D hypothetical protein 1464140..1464301 Streptococcus pneumoniae Taiwan19F-14 7686881 YP_002742940.1 CDS SPT_1538 NC_012469.1 1464273 1465424 R identified by match to protein family HMM PF07690; major facilitator superfamily transporter complement(1464273..1465424) Streptococcus pneumoniae Taiwan19F-14 7686589 YP_002742941.1 CDS SPT_1540 NC_012469.1 1465396 1465512 D identified by glimmer; putative; hypothetical protein 1465396..1465512 Streptococcus pneumoniae Taiwan19F-14 7686344 YP_002742942.1 CDS SPT_1541 NC_012469.1 1465664 1466293 R hypothetical protein complement(1465664..1466293) Streptococcus pneumoniae Taiwan19F-14 7686073 YP_002742943.1 CDS phnA NC_012469.1 1466296 1466634 R identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686; alkylphosphonate utilization operon protein PhnA complement(1466296..1466634) Streptococcus pneumoniae Taiwan19F-14 7686793 YP_002742944.1 CDS cmk NC_012469.1 1466765 1467436 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1466765..1467436) Streptococcus pneumoniae Taiwan19F-14 7686478 YP_002742945.1 CDS SPT_1544 NC_012469.1 1467445 1467921 R hypothetical protein complement(1467445..1467921) Streptococcus pneumoniae Taiwan19F-14 7685955 YP_002742946.1 CDS SPT_1545 NC_012469.1 1467967 1468179 D ferredoxin 1467967..1468179 Streptococcus pneumoniae Taiwan19F-14 7687143 YP_002742947.1 CDS SPT_1546 NC_012469.1 1468230 1469195 R identified by match to protein family HMM PF00535; bactoprenol glucosyl transferase complement(1468230..1469195) Streptococcus pneumoniae Taiwan19F-14 7686783 YP_002742948.1 CDS galE1 NC_012469.1 1469197 1470216 R identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase complement(1469197..1470216) Streptococcus pneumoniae Taiwan19F-14 7685643 YP_002742949.1 CDS SPT_1549 NC_012469.1 1470517 1471620 R identified by match to protein family HMM PF01266; FAD dependent oxidoreductase complement(1470517..1471620) Streptococcus pneumoniae Taiwan19F-14 7686758 YP_002742950.1 CDS SPT_1550 NC_012469.1 1471637 1472434 R identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein complement(1471637..1472434) Streptococcus pneumoniae Taiwan19F-14 7687028 YP_002742951.1 CDS SPT_1551 NC_012469.1 1472421 1473098 R identified by match to protein family HMM PF04816; Bcl-2 family protein complement(1472421..1473098) Streptococcus pneumoniae Taiwan19F-14 7687083 YP_002742952.1 CDS SPT_1552 NC_012469.1 1473647 1473823 D identified by glimmer; putative; hypothetical protein 1473647..1473823 Streptococcus pneumoniae Taiwan19F-14 7686397 YP_002742953.1 CDS SPT_1553 NC_012469.1 1474024 1474266 D identified by glimmer; putative; hypothetical protein 1474024..1474266 Streptococcus pneumoniae Taiwan19F-14 7685772 YP_002742954.1 CDS SPT_1554 NC_012469.1 1474718 1475989 R identified by match to protein family HMM PF00665; IS3-Spn1, transposase complement(1474718..1475989) Streptococcus pneumoniae Taiwan19F-14 7686280 YP_002742955.1 CDS tkt1 NC_012469.1 1476362 1478332 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1476362..1478332) Streptococcus pneumoniae Taiwan19F-14 7686564 YP_002742956.1 CDS SPT_1556 NC_012469.1 1478369 1479064 R identified by match to protein family HMM PF00834; allulose-6-phosphate 3-epimerase complement(1478369..1479064) Streptococcus pneumoniae Taiwan19F-14 7686489 YP_002742957.1 CDS SPT_1557 NC_012469.1 1479075 1480160 R identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427; PTS system, IIC component complement(1479075..1480160) Streptococcus pneumoniae Taiwan19F-14 7686526 YP_002742958.1 CDS SPT_1559 NC_012469.1 1480525 1480974 R identified by match to protein family HMM PF00359; match to protein family HMM TIGR00848; PTS system, IIA component complement(1480525..1480974) Streptococcus pneumoniae Taiwan19F-14 7686102 YP_002742959.1 CDS SPT_1560 NC_012469.1 1480952 1481380 R identified by match to protein family HMM PF00359; PTS system, nitrogen regulatory component IIA, putative complement(1480952..1481380) Streptococcus pneumoniae Taiwan19F-14 7687023 YP_002742960.1 CDS SPT_1561 NC_012469.1 1481373 1482836 R identified by match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279; putative transcription antiterminator BglG family protein complement(1481373..1482836) Streptococcus pneumoniae Taiwan19F-14 7686387 YP_002742961.1 CDS SPT_1562 NC_012469.1 1483365 1485701 R identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; cation-transporting ATPase, E1-E2 family complement(1483365..1485701) Streptococcus pneumoniae Taiwan19F-14 7687364 YP_002742962.1 CDS SPT_1563 NC_012469.1 1485834 1486583 D identified by match to protein family HMM PF01553; acyltransferase family protein 1485834..1486583 Streptococcus pneumoniae Taiwan19F-14 7687269 YP_002742963.1 CDS SPT_1564 NC_012469.1 1486876 1487490 R identified by match to protein family HMM PF03596; match to protein family HMM TIGR00779; CadD complement(1486876..1487490) Streptococcus pneumoniae Taiwan19F-14 7685215 YP_002742964.1 CDS rpsO NC_012469.1 1488307 1488576 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1488307..1488576) Streptococcus pneumoniae Taiwan19F-14 7685430 YP_002742965.1 CDS SPT_1566 NC_012469.1 1488717 1489346 R YwnB complement(1488717..1489346) Streptococcus pneumoniae Taiwan19F-14 7687170 YP_002742966.1 CDS SPT_1567 NC_012469.1 1489409 1489531 D hypothetical protein 1489409..1489531 Streptococcus pneumoniae Taiwan19F-14 7685902 YP_002742967.1 CDS SPT_1569 NC_012469.1 1490362 1490538 D identified by glimmer; putative; hypothetical protein 1490362..1490538 Streptococcus pneumoniae Taiwan19F-14 7686180 YP_002742968.1 CDS thrS NC_012469.1 1490596 1492539 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1490596..1492539 Streptococcus pneumoniae Taiwan19F-14 7685795 YP_002742969.1 CDS SPT_1571 NC_012469.1 1492588 1493562 R identified by match to protein family HMM PF02518; histidine kinase complement(1492588..1493562) Streptococcus pneumoniae Taiwan19F-14 7685759 YP_002742970.1 CDS SPT_1572 NC_012469.1 1493555 1494232 R identified by match to protein family HMM PF00072; match to protein family HMM PF00486; response regulator complement(1493555..1494232) Streptococcus pneumoniae Taiwan19F-14 7685761 YP_002742971.1 CDS SPT_1573 NC_012469.1 1494388 1495461 D hypothetical protein 1494388..1495461 Streptococcus pneumoniae Taiwan19F-14 7687273 YP_002742972.1 CDS SPT_1574 NC_012469.1 1495552 1495854 R hypothetical protein complement(1495552..1495854) Streptococcus pneumoniae Taiwan19F-14 7685384 YP_002742973.1 CDS SPT_1575 NC_012469.1 1495922 1496359 R identified by match to protein family HMM PF02082; Rrf2 family protein complement(1495922..1496359) Streptococcus pneumoniae Taiwan19F-14 7686053 YP_002742974.1 CDS SPT_1576 NC_012469.1 1496435 1497277 R identified by match to protein family HMM PF00149; metallophosphoesterase complement(1496435..1497277) Streptococcus pneumoniae Taiwan19F-14 7687203 YP_002742975.1 CDS SPT_1577 NC_012469.1 1497389 1498039 D identified by match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron-dependent transcriptional regulator 1497389..1498039 Streptococcus pneumoniae Taiwan19F-14 7686680 YP_002742976.1 CDS SPT_1578 NC_012469.1 1498020 1498211 D hypothetical protein 1498020..1498211 Streptococcus pneumoniae Taiwan19F-14 7686861 YP_002742977.1 CDS SPT_1579 NC_012469.1 1498237 1498755 D identified by glimmer; putative; hypothetical protein 1498237..1498755 Streptococcus pneumoniae Taiwan19F-14 7687136 YP_002742978.1 CDS SPT_1580 NC_012469.1 1498752 1498883 D identified by glimmer; putative; hypothetical protein 1498752..1498883 Streptococcus pneumoniae Taiwan19F-14 7687132 YP_002742979.1 CDS SPT_1581 NC_012469.1 1499276 1500622 R identified by match to protein family HMM PF01609; Spn1 transposase complement(1499276..1500622) Streptococcus pneumoniae Taiwan19F-14 7686908 YP_002742980.1 CDS SPT_1582 NC_012469.1 1500824 1501135 D hypothetical protein 1500824..1501135 Streptococcus pneumoniae Taiwan19F-14 7686041 YP_002742981.1 CDS SPT_1583 NC_012469.1 1501409 1501570 D hypothetical protein 1501409..1501570 Streptococcus pneumoniae Taiwan19F-14 7686472 YP_002742982.1 CDS dtd NC_012469.1 1501609 1502052 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1501609..1502052) Streptococcus pneumoniae Taiwan19F-14 7687275 YP_002742983.1 CDS spoT NC_012469.1 1502082 1504304 R identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; guanosine-3,5-bis(diphosphate) 3-pyrophosphohydrolase complement(1502082..1504304) Streptococcus pneumoniae Taiwan19F-14 7686828 YP_002742984.1 CDS SPT_1586 NC_012469.1 1505298 1505927 D identified by match to protein family HMM PF00753; metallo-beta-lactamase superfamily protein 1505298..1505927 Streptococcus pneumoniae Taiwan19F-14 7685408 YP_002742985.1 CDS SPT_1587 NC_012469.1 1506050 1507942 R identified by match to protein family HMM PF01431; match to protein family HMM PF05649; endopeptidase O complement(1506050..1507942) Streptococcus pneumoniae Taiwan19F-14 7685514 YP_002742986.1 CDS SPT_1588 NC_012469.1 1508233 1508955 D identified by match to protein family HMM PF00005; manganese transport system ATP-binding protein MntA 1508233..1508955 Streptococcus pneumoniae Taiwan19F-14 7685352 YP_002742987.1 CDS SPT_1589 NC_012469.1 1508952 1509800 D identified by match to protein family HMM PF00950; manganese transport system membrane protein MntB 1508952..1509800 Streptococcus pneumoniae Taiwan19F-14 7686376 YP_002742988.1 CDS SPT_1590 NC_012469.1 1509832 1510761 D identified by match to protein family HMM PF01297; manganese ABC transporter substrate-binding lipoprotein (Adhesin B) (Saliva-binding protein) 1509832..1510761 Streptococcus pneumoniae Taiwan19F-14 7685851 YP_002742989.1 CDS tpx NC_012469.1 1510884 1511375 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1510884..1511375 Streptococcus pneumoniae Taiwan19F-14 7685991 YP_002742990.1 CDS SPT_1592 NC_012469.1 1511471 1514179 R identified by match to protein family HMM PF02687; efflux ABC transporter, permease protein complement(1511471..1514179) Streptococcus pneumoniae Taiwan19F-14 7687259 YP_002742991.1 CDS SPT_1593 NC_012469.1 1514181 1514882 R identified by match to protein family HMM PF00005; macrolide export ATP-binding/permease protein MacB complement(1514181..1514882) Streptococcus pneumoniae Taiwan19F-14 7685735 YP_002742992.1 CDS SPT_1594 NC_012469.1 1515132 1517543 R alpha-fucosidase complement(1515132..1517543) Streptococcus pneumoniae Taiwan19F-14 7685251 YP_002742993.1 CDS gpmA NC_012469.1 1517596 1518288 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1517596..1518288) Streptococcus pneumoniae Taiwan19F-14 7685918 YP_002742994.1 CDS SPT_1596 NC_012469.1 1518339 1518527 R hypothetical protein complement(1518339..1518527) Streptococcus pneumoniae Taiwan19F-14 7686084 YP_002742995.1 CDS SPT_1597 NC_012469.1 1518823 1519185 R integral membrane protein complement(1518823..1519185) Streptococcus pneumoniae Taiwan19F-14 7685440 YP_002742996.1 CDS ileS NC_012469.1 1519593 1522385 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1519593..1522385) Streptococcus pneumoniae Taiwan19F-14 7687113 YP_002742997.1 CDS SPT_1599 NC_012469.1 1522638 1522754 R hypothetical protein complement(1522638..1522754) Streptococcus pneumoniae Taiwan19F-14 7686925 YP_002742998.1 CDS SPT_1600 NC_012469.1 1522733 1523521 R identified by match to protein family HMM PF05103; cell-division initiation protein complement(1522733..1523521) Streptococcus pneumoniae Taiwan19F-14 7687366 YP_002742999.1 CDS SPT_1601 NC_012469.1 1523530 1524315 R identified by match to protein family HMM PF01479; YlmH protein complement(1523530..1524315) Streptococcus pneumoniae Taiwan19F-14 7687042 YP_002743000.1 CDS SPT_1602 NC_012469.1 1524312 1524575 R identified by match to protein family HMM PF02325; yggt family, putative complement(1524312..1524575) Streptococcus pneumoniae Taiwan19F-14 7686121 YP_002743001.1 CDS SPT_1603 NC_012469.1 1524575 1525114 R identified by match to protein family HMM PF04472; YlmF protein complement(1524575..1525114) Streptococcus pneumoniae Taiwan19F-14 7686230 YP_002743002.1 CDS SPT_1604 NC_012469.1 1525124 1525795 R identified by match to protein family HMM TIGR00044; pyridoxal phosphate enzyme, YggS family complement(1525124..1525795) Streptococcus pneumoniae Taiwan19F-14 7685696 YP_002743003.1 CDS ftsZ NC_012469.1 1525800 1527059 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1525800..1527059) Streptococcus pneumoniae Taiwan19F-14 7687248 YP_002743004.1 CDS ftsA NC_012469.1 1527076 1528449 R identified by match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA complement(1527076..1528449) Streptococcus pneumoniae Taiwan19F-14 7685747 YP_002743005.1 CDS SPT_1607 NC_012469.1 1528669 1529373 R identified by match to protein family HMM TIGR02206; hypothetical protein complement(1528669..1529373) Streptococcus pneumoniae Taiwan19F-14 7686388 YP_002743006.1 CDS SPT_1608 NC_012469.1 1529464 1530075 R identified by match to protein family HMM PF00293; MutT/nudix family protein complement(1529464..1530075) Streptococcus pneumoniae Taiwan19F-14 7685373 YP_002743007.1 CDS SPT_1609 NC_012469.1 1530062 1531435 R identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase complement(1530062..1531435) Streptococcus pneumoniae Taiwan19F-14 7686112 YP_002743008.1 CDS ddl NC_012469.1 1531519 1532562 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(1531519..1532562) Streptococcus pneumoniae Taiwan19F-14 7686678 YP_002743009.1 CDS recR NC_012469.1 1532738 1533334 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(1532738..1533334) Streptococcus pneumoniae Taiwan19F-14 7686661 YP_002743010.1 CDS SPT_1612 NC_012469.1 1533345 1535387 R identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 2B complement(1533345..1535387) Streptococcus pneumoniae Taiwan19F-14 7687404 YP_002743011.1 CDS SPT_1613 NC_012469.1 1535596 1536447 D identified by match to protein family HMM PF01380; match to protein family HMM PF01418; transcriptional regulator, RpiR family 1535596..1536447 Streptococcus pneumoniae Taiwan19F-14 7686157 YP_002743012.1 CDS SPT_1614 NC_012469.1 1536463 1537347 R identified by match to protein family HMM PF00480; glucokinase complement(1536463..1537347) Streptococcus pneumoniae Taiwan19F-14 7686090 YP_002743013.1 CDS SPT_1615 NC_012469.1 1537365 1538282 R identified by match to protein family HMM PF00701; N-acetylneuraminate lyase complement(1537365..1538282) Streptococcus pneumoniae Taiwan19F-14 7686621 YP_002743014.1 CDS SPT_1617 NC_012469.1 1539387 1539695 R hypothetical protein complement(1539387..1539695) Streptococcus pneumoniae Taiwan19F-14 7687036 YP_002743015.1 CDS SPT_1618 NC_012469.1 1539837 1540289 R identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein complement(1539837..1540289) Streptococcus pneumoniae Taiwan19F-14 7685848 YP_002743016.1 CDS SPT_1619 NC_012469.1 1540562 1541401 R identified by match to protein family HMM PF00528; sugar ABC transporter permease complement(1540562..1541401) Streptococcus pneumoniae Taiwan19F-14 7685428 YP_002743017.1 CDS SPT_1620 NC_012469.1 1541417 1542304 R identified by match to protein family HMM PF00528; sugar ABC transporter permease complement(1541417..1542304) Streptococcus pneumoniae Taiwan19F-14 7685905 YP_002743018.1 CDS SPT_1621 NC_012469.1 1542536 1543864 R identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein complement(1542536..1543864) Streptococcus pneumoniae Taiwan19F-14 7685451 YP_002743019.1 CDS SPT_1622 NC_012469.1 1543989 1545506 R identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; pts system maltose- and glucose-specific eiicb component complement(1543989..1545506) Streptococcus pneumoniae Taiwan19F-14 7686856 YP_002743020.1 CDS SPT_1623 NC_012469.1 1545525 1546223 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(1545525..1546223) Streptococcus pneumoniae Taiwan19F-14 7687095 YP_002743021.1 CDS SPT_1624 NC_012469.1 1546397 1547500 R identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894; match to protein family HMM PF03447; putative oxidoreductase YjhC complement(1546397..1547500) Streptococcus pneumoniae Taiwan19F-14 7685481 YP_002743022.1 CDS SPT_1625 NC_012469.1 1547513 1549606 R identified by match to protein family HMM PF02012; match to protein family HMM PF02973; sialidase B (Neuraminidase B) complement(1547513..1549606) Streptococcus pneumoniae Taiwan19F-14 7687190 YP_002743023.1 CDS SPT_1626 NC_012469.1 1549624 1550457 R identified by match to protein family HMM PF00528; ABC transporter permease complement(1549624..1550457) Streptococcus pneumoniae Taiwan19F-14 7686188 YP_002743024.1 CDS SPT_1627 NC_012469.1 1550457 1551341 R identified by match to protein family HMM PF00528; ABC transporter permease complement(1550457..1551341) Streptococcus pneumoniae Taiwan19F-14 7685457 YP_002743025.1 CDS SPT_1628 NC_012469.1 1551420 1552757 R identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein complement(1551420..1552757) Streptococcus pneumoniae Taiwan19F-14 7686224 YP_002743026.1 CDS SPT_1629 NC_012469.1 1552776 1553228 R identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022; hypothetical protein complement(1552776..1553228) Streptococcus pneumoniae Taiwan19F-14 7686134 YP_002743027.1 CDS SPT_1630 NC_012469.1 1554242 1557118 R identified by match to protein family HMM PF02012; match to protein family HMM PF02973; match to protein family HMM TIGR01167; neuraminidase complement(1554242..1557118) Streptococcus pneumoniae Taiwan19F-14 7685395 YP_002743028.1 CDS SPT_1631 NC_012469.1 1557475 1557702 R hypothetical protein complement(1557475..1557702) Streptococcus pneumoniae Taiwan19F-14 7685949 YP_002743029.1 CDS SPT_1632 NC_012469.1 1558100 1558591 D identified by glimmer; putative; hypothetical protein 1558100..1558591 Streptococcus pneumoniae Taiwan19F-14 7686773 YP_002743030.1 CDS recG NC_012469.1 1560210 1562225 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1560210..1562225) Streptococcus pneumoniae Taiwan19F-14 7687332 YP_002743031.1 CDS alr NC_012469.1 1562244 1563347 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1562244..1563347) Streptococcus pneumoniae Taiwan19F-14 7685534 YP_002743032.1 CDS acpS NC_012469.1 1563337 1563699 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1563337..1563699) Streptococcus pneumoniae Taiwan19F-14 7685677 YP_002743033.1 CDS SPT_1638 NC_012469.1 1563744 1564775 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1563744..1564775) Streptococcus pneumoniae Taiwan19F-14 7685462 YP_002743034.1 CDS SPT_1639 NC_012469.1 1564777 1565808 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1564777..1565808) Streptococcus pneumoniae Taiwan19F-14 7685744 YP_002743035.1 CDS secA NC_012469.1 1565889 1568402 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1565889..1568402) Streptococcus pneumoniae Taiwan19F-14 7686493 YP_002743036.1 CDS SPT_1641 NC_012469.1 1568548 1568835 R hypothetical protein complement(1568548..1568835) Streptococcus pneumoniae Taiwan19F-14 7685274 YP_002743037.1 CDS SPT_1642 NC_012469.1 1568846 1569496 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1568846..1569496) Streptococcus pneumoniae Taiwan19F-14 7685688 YP_002743038.1 CDS SPT_1643 NC_012469.1 1569500 1570141 R hypothetical protein complement(1569500..1570141) Streptococcus pneumoniae Taiwan19F-14 7686498 YP_002743039.1 CDS SPT_1644 NC_012469.1 1570134 1570925 R hypothetical protein complement(1570134..1570925) Streptococcus pneumoniae Taiwan19F-14 7687097 YP_002743040.1 CDS SPT_1645 NC_012469.1 1571110 1571448 R identified by glimmer; putative; hypothetical protein complement(1571110..1571448) Streptococcus pneumoniae Taiwan19F-14 7687286 YP_002743041.1 CDS SPT_1646 NC_012469.1 1571585 1571932 R identified by glimmer; putative; hypothetical protein complement(1571585..1571932) Streptococcus pneumoniae Taiwan19F-14 7686479 YP_002743042.1 CDS engA NC_012469.1 1572011 1573321 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(1572011..1573321) Streptococcus pneumoniae Taiwan19F-14 7685988 YP_002743043.1 CDS SPT_1648 NC_012469.1 1573335 1574048 R identified by match to protein family HMM PF00881; nitroreductase family protein complement(1573335..1574048) Streptococcus pneumoniae Taiwan19F-14 7685763 YP_002743044.1 CDS SPT_1649 NC_012469.1 1574045 1574941 R Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI complement(1574045..1574941) Streptococcus pneumoniae Taiwan19F-14 7685230 YP_002743045.1 CDS SPT_1650 NC_012469.1 1574942 1576111 R identified by match to protein family HMM PF07261; replication initiation and membrane attachment protein complement(1574942..1576111) Streptococcus pneumoniae Taiwan19F-14 7686407 YP_002743046.1 CDS nrdR NC_012469.1 1576112 1576585 R identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR complement(1576112..1576585) Streptococcus pneumoniae Taiwan19F-14 7685412 YP_002743047.1 CDS SPT_1652 NC_012469.1 1576725 1577090 D identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1576725..1577090 Streptococcus pneumoniae Taiwan19F-14 7685960 YP_002743048.1 CDS SPT_1653 NC_012469.1 1577095 1577790 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1577095..1577790 Streptococcus pneumoniae Taiwan19F-14 7686212 YP_002743049.1 CDS SPT_1654 NC_012469.1 1577807 1578574 D hypothetical protein 1577807..1578574 Streptococcus pneumoniae Taiwan19F-14 7687314 YP_002743050.1 CDS SPT_1655 NC_012469.1 1578927 1580126 R Na+ ABC transporter permease complement(1578927..1580126) Streptococcus pneumoniae Taiwan19F-14 7686734 YP_002743051.1 CDS SPT_1656 NC_012469.1 1580123 1581016 R identified by match to protein family HMM PF00005; Na+ ABC transporter ATP-binding protein complement(1580123..1581016) Streptococcus pneumoniae Taiwan19F-14 7685263 YP_002743052.1 CDS SPT_1657 NC_012469.1 1581139 1581330 D chlorohydrolase 1581139..1581330 Streptococcus pneumoniae Taiwan19F-14 7686385 YP_002743053.1 CDS SPT_1658 NC_012469.1 1582332 1582949 D identified by match to protein family HMM PF09335; hypothetical protein 1582332..1582949 Streptococcus pneumoniae Taiwan19F-14 7685727 YP_002743054.1 CDS SPT_1659 NC_012469.1 1583269 1584156 R identified by match to protein family HMM PF00480; fructokinase complement(1583269..1584156) Streptococcus pneumoniae Taiwan19F-14 7687319 YP_002743055.1 CDS SPT_1660 NC_012469.1 1584305 1586188 R identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01996; pts system, sucrose-specific iibc component complement(1584305..1586188) Streptococcus pneumoniae Taiwan19F-14 7687402 YP_002743056.1 CDS SPT_1661 NC_012469.1 1586380 1586496 D identified by glimmer; putative; hypothetical protein 1586380..1586496 Streptococcus pneumoniae Taiwan19F-14 7686677 YP_002743057.1 CDS SPT_1662 NC_012469.1 1586565 1588019 D identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase (Sucrase) (Invertase) 1586565..1588019 Streptococcus pneumoniae Taiwan19F-14 7686151 YP_002743058.1 CDS SPT_1663 NC_012469.1 1588000 1588965 D identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose operon repressor (Scr operon regulatory protein) 1588000..1588965 Streptococcus pneumoniae Taiwan19F-14 7686442 YP_002743059.1 CDS SPT_1664 NC_012469.1 1589000 1590274 R identified by match to protein family HMM TIGR00532; hydroxymethylglutaryl-CoA reductase, degradative complement(1589000..1590274) Streptococcus pneumoniae Taiwan19F-14 7685311 YP_002743060.1 CDS SPT_1665 NC_012469.1 1590274 1591470 R identified by match to protein family HMM PF01154; match to protein family HMM PF08540; match to protein family HMM TIGR01835; hydroxymethylglutaryl-CoA synthase complement(1590274..1591470) Streptococcus pneumoniae Taiwan19F-14 7686772 YP_002743061.1 CDS SPT_1668 NC_012469.1 1592391 1592840 R hypothetical protein complement(1592391..1592840) Streptococcus pneumoniae Taiwan19F-14 7685423 YP_002743062.1 CDS SPT_1669 NC_012469.1 1592842 1593600 R identified by match to protein family HMM PF06738; hypothetical protein complement(1592842..1593600) Streptococcus pneumoniae Taiwan19F-14 7685725 YP_002743063.1 CDS SPT_1670 NC_012469.1 1593715 1595694 R identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793; Stk1 complement(1593715..1595694) Streptococcus pneumoniae Taiwan19F-14 7686287 YP_002743064.1 CDS SPT_1671 NC_012469.1 1595691 1596431 R identified by match to protein family HMM PF00481; protein phosphatase PrpC complement(1595691..1596431) Streptococcus pneumoniae Taiwan19F-14 7686528 YP_002743065.1 CDS sun NC_012469.1 1596446 1597759 R identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; ribosomal RNA small subunit methyltransferase B complement(1596446..1597759) Streptococcus pneumoniae Taiwan19F-14 7686383 YP_002743066.1 CDS fmt NC_012469.1 1597752 1598687 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1597752..1598687) Streptococcus pneumoniae Taiwan19F-14 7685981 YP_002743067.1 CDS SPT_1674 NC_012469.1 1598700 1601096 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1598700..1601096) Streptococcus pneumoniae Taiwan19F-14 7685536 YP_002743068.1 CDS SPT_1675 NC_012469.1 1601162 1601476 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1601162..1601476) Streptococcus pneumoniae Taiwan19F-14 7686403 YP_002743069.1 CDS gmk NC_012469.1 1601501 1602127 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1601501..1602127) Streptococcus pneumoniae Taiwan19F-14 7685774 YP_002743070.1 CDS SPT_1677 NC_012469.1 1602257 1603870 R identified by match to protein family HMM PF00013; match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR03319; hypothetical protein complement(1602257..1603870) Streptococcus pneumoniae Taiwan19F-14 7686378 YP_002743071.1 CDS SPT_1678 NC_012469.1 1604139 1604318 R prevent-host-death family protein complement(1604139..1604318) Streptococcus pneumoniae Taiwan19F-14 7687356 YP_002743072.1 CDS SPT_1679 NC_012469.1 1604478 1605824 D identified by match to protein family HMM PF01609; Spn1 transposase 1604478..1605824 Streptococcus pneumoniae Taiwan19F-14 7687247 YP_002743073.1 CDS SPT_1680 NC_012469.1 1606315 1607412 R identified by match to protein family HMM PF05636; hypothetical protein complement(1606315..1607412) Streptococcus pneumoniae Taiwan19F-14 7686802 YP_002743074.1 CDS SPT_1681 NC_012469.1 1607422 1608168 R identified by match to protein family HMM PF08241; match to protein family HMM PF08242; SAM-dependent methyltransferase complement(1607422..1608168) Streptococcus pneumoniae Taiwan19F-14 7685777 YP_002743075.1 CDS SPT_1682 NC_012469.1 1608271 1608624 R identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; putative iojap homolog complement(1608271..1608624) Streptococcus pneumoniae Taiwan19F-14 7686365 YP_002743076.1 CDS SPT_1683 NC_012469.1 1608637 1609137 R identified by match to protein family HMM PF00857; isochorismatase family protein complement(1608637..1609137) Streptococcus pneumoniae Taiwan19F-14 7686598 YP_002743077.1 CDS SPT_1684 NC_012469.1 1609138 1609731 R identified by match to protein family HMM PF01966; match to protein family HMM TIGR00488; hypothetical protein complement(1609138..1609731) Streptococcus pneumoniae Taiwan19F-14 7685522 YP_002743078.1 CDS nadD NC_012469.1 1609731 1610360 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1609731..1610360) Streptococcus pneumoniae Taiwan19F-14 7687048 YP_002743079.1 CDS SPT_1686 NC_012469.1 1610412 1610723 R identified by match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein complement(1610412..1610723) Streptococcus pneumoniae Taiwan19F-14 7686009 YP_002743080.1 CDS SPT_1687 NC_012469.1 1610937 1612043 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH complement(1610937..1612043) Streptococcus pneumoniae Taiwan19F-14 7685779 YP_002743081.1 CDS yqeG NC_012469.1 1612046 1612573 R identified by match to protein family HMM TIGR01662; match to protein family HMM TIGR01668; had superfamily (subfamily iiia) phosphatase complement(1612046..1612573) Streptococcus pneumoniae Taiwan19F-14 7685618 YP_002743082.1 CDS SPT_1689 NC_012469.1 1612588 1613496 R identified by match to protein family HMM PF01544; CorA - magnesium and cobalt transporter complement(1612588..1613496) Streptococcus pneumoniae Taiwan19F-14 7686594 YP_002743083.1 CDS SPT_1690 NC_012469.1 1613553 1614149 R identified by match to protein family HMM PF00924; small conductance mechanosensitive ion channel complement(1613553..1614149) Streptococcus pneumoniae Taiwan19F-14 7686416 YP_002743084.1 CDS SPT_1693 NC_012469.1 1615528 1616481 D identified by match to protein family HMM PF06081; integral membrane protein 1615528..1616481 Streptococcus pneumoniae Taiwan19F-14 7686305 YP_002743085.1 CDS SPT_1694 NC_012469.1 1616624 1617004 D identified by match to protein family HMM PF01047; transcriptional regulator, putative 1616624..1617004 Streptococcus pneumoniae Taiwan19F-14 7685752 YP_002743086.1 CDS SPT_1695 NC_012469.1 1617103 1617324 D hypothetical protein 1617103..1617324 Streptococcus pneumoniae Taiwan19F-14 7686234 YP_002743087.1 CDS trx NC_012469.1 1617341 1617655 D identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 1617341..1617655 Streptococcus pneumoniae Taiwan19F-14 7686630 YP_002743088.1 CDS SPT_1697 NC_012469.1 1617960 1618493 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1617960..1618493 Streptococcus pneumoniae Taiwan19F-14 7687246 YP_002743089.1 CDS SPT_1698 NC_012469.1 1618543 1618881 D identified by glimmer; putative; hypothetical protein 1618543..1618881 Streptococcus pneumoniae Taiwan19F-14 7686548 YP_002743090.1 CDS SPT_1699 NC_012469.1 1618971 1619639 R identified by match to protein family HMM PF00230; aquaporin Z - water channel protein complement(1618971..1619639) Streptococcus pneumoniae Taiwan19F-14 7685831 YP_002743091.1 CDS SPT_1700 NC_012469.1 1619750 1619929 R identified by glimmer; putative; hypothetical protein complement(1619750..1619929) Streptococcus pneumoniae Taiwan19F-14 7686770 YP_002743092.1 CDS SPT_1701 NC_012469.1 1619936 1620310 R identified by glimmer; putative; hypothetical protein complement(1619936..1620310) Streptococcus pneumoniae Taiwan19F-14 7685362 YP_002743093.1 CDS SPT_1702 NC_012469.1 1620372 1620527 R identified by glimmer; putative; hypothetical protein complement(1620372..1620527) Streptococcus pneumoniae Taiwan19F-14 7685952 YP_002743094.1 CDS pepF2 NC_012469.1 1620550 1622346 R identified by match to protein family HMM PF01432; match to protein family HMM PF08439; match to protein family HMM TIGR00181; oligoendopeptidase F complement(1620550..1622346) Streptococcus pneumoniae Taiwan19F-14 7686864 YP_002743095.1 CDS SPT_1704 NC_012469.1 1622357 1623100 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1622357..1623100) Streptococcus pneumoniae Taiwan19F-14 7686050 YP_002743096.1 CDS prmA NC_012469.1 1623102 1624052 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(1623102..1624052) Streptococcus pneumoniae Taiwan19F-14 7686514 YP_002743097.1 CDS SPT_1708 NC_012469.1 1625135 1627270 R hypothetical protein complement(1625135..1627270) Streptococcus pneumoniae Taiwan19F-14 7687126 YP_002743098.1 CDS SPT_1709 NC_012469.1 1627380 1628252 R identified by match to protein family HMM PF00004; ATPase of the AAA+ class complement(1627380..1628252) Streptococcus pneumoniae Taiwan19F-14 7685973 YP_002743099.1 CDS SPT_1710 NC_012469.1 1628524 1628682 R 7,8-dihydro-8-oxoguanine-triphosphatase complement(1628524..1628682) Streptococcus pneumoniae Taiwan19F-14 7686048 YP_002743100.1 CDS SPT_1711 NC_012469.1 1628663 1629751 R identified by match to protein family HMM PF02163; peptidase, M50 family protein complement(1628663..1629751) Streptococcus pneumoniae Taiwan19F-14 7687376 YP_002743101.1 CDS SPT_1712 NC_012469.1 1629770 1630240 R hypothetical protein complement(1629770..1630240) Streptococcus pneumoniae Taiwan19F-14 7685808 YP_002743102.1 CDS SPT_1713 NC_012469.1 1630531 1630983 R identified by match to protein family HMM PF03681; hypothetical protein complement(1630531..1630983) Streptococcus pneumoniae Taiwan19F-14 7685617 YP_002743103.1 CDS SPT_1714 NC_012469.1 1631020 1631199 R identified by match to protein family HMM PF07927; hypothetical protein complement(1631020..1631199) Streptococcus pneumoniae Taiwan19F-14 7686931 YP_002743104.1 CDS SPT_1715 NC_012469.1 1631336 1631515 R hypothetical protein complement(1631336..1631515) Streptococcus pneumoniae Taiwan19F-14 7687326 YP_002743105.1 CDS SPT_1716 NC_012469.1 1631680 1631919 R hypothetical protein complement(1631680..1631919) Streptococcus pneumoniae Taiwan19F-14 7686859 YP_002743106.1 CDS SPT_1717 NC_012469.1 1632189 1633460 D identified by match to protein family HMM PF00004; recombination factor protein RarA 1632189..1633460 Streptococcus pneumoniae Taiwan19F-14 7687218 YP_002743107.1 CDS SPT_1719 NC_012469.1 1634007 1635326 R identified by match to protein family HMM PF00251; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase complement(1634007..1635326) Streptococcus pneumoniae Taiwan19F-14 7685604 YP_002743108.1 CDS SPT_1720 NC_012469.1 1635336 1636952 R identified by match to protein family HMM PF01547; ABC transporter substrate-binding protein complement(1635336..1636952) Streptococcus pneumoniae Taiwan19F-14 7686303 YP_002743109.1 CDS SPT_1721 NC_012469.1 1636981 1637871 R protein LplC complement(1636981..1637871) Streptococcus pneumoniae Taiwan19F-14 7686820 YP_002743110.1 CDS SPT_1722 NC_012469.1 1637882 1638799 R identified by match to protein family HMM PF00528; protein LplB complement(1637882..1638799) Streptococcus pneumoniae Taiwan19F-14 7686955 YP_002743111.1 CDS SPT_1723 NC_012469.1 1638949 1639950 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; sugar-binding transcriptional regulator, LacI family complement(1638949..1639950) Streptococcus pneumoniae Taiwan19F-14 7687151 YP_002743112.1 CDS SPT_1724 NC_012469.1 1640312 1641793 R identified by match to protein family HMM PF05043; match to protein family HMM PF08270; match to protein family HMM PF08279; match to protein family HMM PF08280; M protein trans-acting positive transcriptional regulator complement(1640312..1641793) Streptococcus pneumoniae Taiwan19F-14 7686002 YP_002743113.1 CDS SPT_1725 NC_012469.1 1642236 1642400 D identified by match to protein family HMM PF04226; hypothetical protein 1642236..1642400 Streptococcus pneumoniae Taiwan19F-14 7685487 YP_002743114.1 CDS SPT_1726 NC_012469.1 1642484 1643050 D hypothetical protein 1642484..1643050 Streptococcus pneumoniae Taiwan19F-14 7685930 YP_002743115.1 CDS SPT_1727 NC_012469.1 1643062 1643232 D lipoprotein, putative 1643062..1643232 Streptococcus pneumoniae Taiwan19F-14 7687198 YP_002743116.1 CDS SPT_1728 NC_012469.1 1643271 1643879 D identified by match to protein family HMM PF03780; Gls24 protein 1643271..1643879 Streptococcus pneumoniae Taiwan19F-14 7685273 YP_002743117.1 CDS SPT_1729 NC_012469.1 1643910 1644113 D identified by match to protein family HMM PF05532; hypothetical protein 1643910..1644113 Streptococcus pneumoniae Taiwan19F-14 7685389 YP_002743118.1 CDS SPT_1730 NC_012469.1 1644640 1645086 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family complement(1644640..1645086) Streptococcus pneumoniae Taiwan19F-14 7685980 YP_002743119.1 CDS SPT_1731 NC_012469.1 1645156 1645815 D identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type 4 prepilin peptidase 1645156..1645815 Streptococcus pneumoniae Taiwan19F-14 7685853 YP_002743120.1 CDS SPT_1732 NC_012469.1 1645867 1647018 R identified by match to protein family HMM PF01381; match to protein family HMM PF06114; transcriptional regulator complement(1645867..1647018) Streptococcus pneumoniae Taiwan19F-14 7686555 YP_002743121.1 CDS SPT_1733 NC_012469.1 1647033 1647764 R hypothetical protein complement(1647033..1647764) Streptococcus pneumoniae Taiwan19F-14 7685734 YP_002743122.1 CDS trpA NC_012469.1 1648066 1648842 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1648066..1648842) Streptococcus pneumoniae Taiwan19F-14 7686060 YP_002743123.1 CDS trpB NC_012469.1 1648835 1650058 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1648835..1650058) Streptococcus pneumoniae Taiwan19F-14 7685391 YP_002743124.1 CDS trpF NC_012469.1 1650036 1650635 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(1650036..1650635) Streptococcus pneumoniae Taiwan19F-14 7685355 YP_002743125.1 CDS trpC NC_012469.1 1650622 1651389 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase complement(1650622..1651389) Streptococcus pneumoniae Taiwan19F-14 7686753 YP_002743126.1 CDS trpD NC_012469.1 1651386 1652390 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1651386..1652390) Streptococcus pneumoniae Taiwan19F-14 7685916 YP_002743127.1 CDS pabA NC_012469.1 1652401 1652967 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1652401..1652967) Streptococcus pneumoniae Taiwan19F-14 7685471 YP_002743128.1 CDS trpE NC_012469.1 1652964 1654325 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1652964..1654325) Streptococcus pneumoniae Taiwan19F-14 7686475 YP_002743129.1 CDS SPT_1741 NC_012469.1 1654697 1655038 R chlorohydrolase complement(1654697..1655038) Streptococcus pneumoniae Taiwan19F-14 7686512 YP_002743130.1 CDS SPT_1742 NC_012469.1 1655646 1656647 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; catabolite control protein complement(1655646..1656647) Streptococcus pneumoniae Taiwan19F-14 7685357 YP_002743131.1 CDS SPT_1743 NC_012469.1 1657218 1657928 R identified by match to protein family HMM PF02308; putative Mg2+ transporter-C (MgtC) family protein complement(1657218..1657928) Streptococcus pneumoniae Taiwan19F-14 7686096 YP_002743132.1 CDS SPT_1744 NC_012469.1 1657931 1659622 R identified by match to protein family HMM PF00528; binding-protein-dependent transport systems inner membrane component complement(1657931..1659622) Streptococcus pneumoniae Taiwan19F-14 7686338 YP_002743133.1 CDS SPT_1745 NC_012469.1 1659634 1660644 R identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402; spermidine/putrescine import ATP-binding protein PotA complement(1659634..1660644) Streptococcus pneumoniae Taiwan19F-14 7687134 YP_002743134.1 CDS SPT_1746 NC_012469.1 1660747 1661814 R ABC transporter substrate-binding protein complement(1660747..1661814) Streptococcus pneumoniae Taiwan19F-14 7686706 YP_002743135.1 CDS SPT_1747 NC_012469.1 1661839 1662498 R identified by match to protein family HMM PF08975; hypothetical protein complement(1661839..1662498) Streptococcus pneumoniae Taiwan19F-14 7686218 YP_002743136.1 CDS galE2 NC_012469.1 1662665 1663675 R identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase complement(1662665..1663675) Streptococcus pneumoniae Taiwan19F-14 7685733 YP_002743137.1 CDS galT1 NC_012469.1 1663688 1665163 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(1663688..1665163) Streptococcus pneumoniae Taiwan19F-14 7685524 YP_002743138.1 CDS SPT_1750 NC_012469.1 1665176 1665817 R identified by match to protein family HMM PF01895; PhoU family complement(1665176..1665817) Streptococcus pneumoniae Taiwan19F-14 7686295 YP_002743139.1 CDS SPT_1751 NC_012469.1 1665875 1666621 R hypothetical protein complement(1665875..1666621) Streptococcus pneumoniae Taiwan19F-14 7686536 YP_002743140.1 CDS SPT_1752 NC_012469.1 1666605 1668683 R identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168; cell wall surface anchor family protein complement(1666605..1668683) Streptococcus pneumoniae Taiwan19F-14 7686958 YP_002743141.1 CDS SPT_1753 NC_012469.1 1669191 1669310 R hypothetical protein complement(1669191..1669310) Streptococcus pneumoniae Taiwan19F-14 7686077 YP_002743142.1 CDS SPT_1754 NC_012469.1 1669604 1670830 R identified by match to protein family HMM PF01041; Cps7G complement(1669604..1670830) Streptococcus pneumoniae Taiwan19F-14 7686164 YP_002743143.1 CDS SPT_1755 NC_012469.1 1670873 1671565 R identified by match to protein family HMM PF02397; sugar transferase family protein complement(1670873..1671565) Streptococcus pneumoniae Taiwan19F-14 7686462 YP_002743144.1 CDS SPT_1756 NC_012469.1 1671749 1673491 R identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein complement(1671749..1673491) Streptococcus pneumoniae Taiwan19F-14 7687152 YP_002743145.1 CDS SPT_1757 NC_012469.1 1673481 1675226 R identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein complement(1673481..1675226) Streptococcus pneumoniae Taiwan19F-14 7685932 YP_002743146.1 CDS SPT_1758 NC_012469.1 1675432 1675728 R identified by glimmer; putative; hypothetical protein complement(1675432..1675728) Streptococcus pneumoniae Taiwan19F-14 7686565 YP_002743147.1 CDS SPT_1759 NC_012469.1 1675881 1676150 R identified by glimmer; putative; hypothetical protein complement(1675881..1676150) Streptococcus pneumoniae Taiwan19F-14 7686351 YP_002743148.1 CDS SPT_1760 NC_012469.1 1676181 1676336 R identified by glimmer; putative; hypothetical protein complement(1676181..1676336) Streptococcus pneumoniae Taiwan19F-14 7687396 YP_002743149.1 CDS xth NC_012469.1 1676470 1677297 D identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1676470..1677297 Streptococcus pneumoniae Taiwan19F-14 7687022 YP_002743150.1 CDS xpt NC_012469.1 1678573 1679154 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1678573..1679154 Streptococcus pneumoniae Taiwan19F-14 7686910 YP_002743151.1 CDS SPT_1765 NC_012469.1 1679154 1680416 D identified by match to protein family HMM PF00860; match to protein family HMM PF00916; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173; xanthine permease 1679154..1680416 Streptococcus pneumoniae Taiwan19F-14 7686665 YP_002743152.1 CDS SPT_1766 NC_012469.1 1680467 1680928 R protein DpnD complement(1680467..1680928) Streptococcus pneumoniae Taiwan19F-14 7685784 YP_002743153.1 CDS SPT_1767 NC_012469.1 1680925 1681689 R identified by match to protein family HMM PF06044; type II restriction enzyme complement(1680925..1681689) Streptococcus pneumoniae Taiwan19F-14 7686800 YP_002743154.1 CDS SPT_1768 NC_012469.1 1681870 1682274 R identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; thioesterase family protein complement(1681870..1682274) Streptococcus pneumoniae Taiwan19F-14 7687078 YP_002743155.1 CDS galT2 NC_012469.1 1682344 1683825 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(1682344..1683825) Streptococcus pneumoniae Taiwan19F-14 7686614 YP_002743156.1 CDS galK NC_012469.1 1683844 1685022 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(1683844..1685022) Streptococcus pneumoniae Taiwan19F-14 7685612 YP_002743157.1 CDS SPT_1771 NC_012469.1 1685186 1686193 D identified by match to protein family HMM PF00356; match to protein family HMM PF00532; GalR, member of GalR-LacI family of transcriptional regulators, binds DNA; regulator of gal operon 1685186..1686193 Streptococcus pneumoniae Taiwan19F-14 7685788 YP_002743158.1 CDS SPT_1772 NC_012469.1 1686239 1687276 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase, zinc-containing complement(1686239..1687276) Streptococcus pneumoniae Taiwan19F-14 7686196 YP_002743159.1 CDS SPT_1773 NC_012469.1 1687277 1687630 R identified by match to protein family HMM PF00376; transcriptional regulator, MerR family complement(1687277..1687630) Streptococcus pneumoniae Taiwan19F-14 7687043 YP_002743160.1 CDS SPT_1774 NC_012469.1 1687874 1688764 R identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation diffusion facilitator transporter - heavy metal transport complement(1687874..1688764) Streptococcus pneumoniae Taiwan19F-14 7687064 YP_002743161.1 CDS SPT_1775 NC_012469.1 1688897 1689433 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1688897..1689433 Streptococcus pneumoniae Taiwan19F-14 7685226 YP_002743162.1 CDS SPT_1776 NC_012469.1 1689599 1690405 R identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528; nicotinamide mononucleotide transporter complement(1689599..1690405) Streptococcus pneumoniae Taiwan19F-14 7686032 YP_002743163.1 CDS SPT_1777 NC_012469.1 1690576 1690692 R identified by glimmer; putative; hypothetical protein complement(1690576..1690692) Streptococcus pneumoniae Taiwan19F-14 7686853 YP_002743164.1 CDS SPT_1778 NC_012469.1 1690750 1692270 R identified by match to protein family HMM PF00528; match to protein family HMM PF04069; choline ABC transporter permease complement(1690750..1692270) Streptococcus pneumoniae Taiwan19F-14 7686915 YP_002743165.1 CDS SPT_1779 NC_012469.1 1692263 1692991 R identified by match to protein family HMM PF00005; choline transport ATP-binding protein opuBA complement(1692263..1692991) Streptococcus pneumoniae Taiwan19F-14 7686092 YP_002743166.1 CDS SPT_1780 NC_012469.1 1693006 1693770 R identified by match to protein family HMM PF07366; hypothetical protein complement(1693006..1693770) Streptococcus pneumoniae Taiwan19F-14 7687375 YP_002743167.1 CDS SPT_1781 NC_012469.1 1693774 1694217 R identified by match to protein family HMM PF01047; transcriptional regulator, MarR family complement(1693774..1694217) Streptococcus pneumoniae Taiwan19F-14 7685326 YP_002743168.1 CDS SPT_1782 NC_012469.1 1694899 1695195 R hypothetical protein complement(1694899..1695195) Streptococcus pneumoniae Taiwan19F-14 7686842 YP_002743169.1 CDS pepA NC_012469.1 1695217 1696281 R identified by match to protein family HMM PF05343; match to protein family HMM TIGR03107; glutamyl aminopeptidase complement(1695217..1696281) Streptococcus pneumoniae Taiwan19F-14 7687101 YP_002743170.1 CDS SPT_1785 NC_012469.1 1697398 1697550 D hypothetical protein 1697398..1697550 Streptococcus pneumoniae Taiwan19F-14 7686620 YP_002743171.1 CDS SPT_1786 NC_012469.1 1697847 1698806 D identified by match to protein family HMM PF01032; Fe3+ ABC transporter permease 1697847..1698806 Streptococcus pneumoniae Taiwan19F-14 7686025 YP_002743172.1 CDS SPT_1787 NC_012469.1 1698796 1699752 D identified by match to protein family HMM PF01032; iron-compound ABC transporter, permease protein 1698796..1699752 Streptococcus pneumoniae Taiwan19F-14 7685280 YP_002743173.1 CDS SPT_1788 NC_012469.1 1699749 1700501 D identified by match to protein family HMM PF00005; ferrichrome transport ATP-binding protein FhuC 1699749..1700501 Streptococcus pneumoniae Taiwan19F-14 7686117 YP_002743174.1 CDS SPT_1789 NC_012469.1 1700597 1701562 D identified by match to protein family HMM PF01497; iron-compound ABC transporter, iron-compound-binding protein 1700597..1701562 Streptococcus pneumoniae Taiwan19F-14 7685815 YP_002743175.1 CDS SPT_1790 NC_012469.1 1701787 1702029 R identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein complement(1701787..1702029) Streptococcus pneumoniae Taiwan19F-14 7686895 YP_002743176.1 CDS rluB NC_012469.1 1702029 1702751 R identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B complement(1702029..1702751) Streptococcus pneumoniae Taiwan19F-14 7686353 YP_002743177.1 CDS scpB NC_012469.1 1702738 1703307 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B complement(1702738..1703307) Streptococcus pneumoniae Taiwan19F-14 7686868 YP_002743178.1 CDS scpA NC_012469.1 1703326 1704054 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(1703326..1704054) Streptococcus pneumoniae Taiwan19F-14 7687129 YP_002743179.1 CDS xerD NC_012469.1 1704054 1704794 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD-like protein complement(1704054..1704794) Streptococcus pneumoniae Taiwan19F-14 7686921 YP_002743180.1 CDS SPT_1795 NC_012469.1 1704785 1705246 R identified by match to protein family HMM PF00571; CBS domain protein complement(1704785..1705246) Streptococcus pneumoniae Taiwan19F-14 7686056 YP_002743181.1 CDS SPT_1796 NC_012469.1 1705243 1705764 R identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040; phosphodiesterase, family complement(1705243..1705764) Streptococcus pneumoniae Taiwan19F-14 7685810 YP_002743182.1 CDS SPT_1797 NC_012469.1 1705740 1706711 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein complement(1705740..1706711) Streptococcus pneumoniae Taiwan19F-14 7687032 YP_002743183.1 CDS murI NC_012469.1 1706708 1707502 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1706708..1707502) Streptococcus pneumoniae Taiwan19F-14 7687343 YP_002743184.1 CDS SPT_1799 NC_012469.1 1707709 1707957 R identified by match to protein family HMM PF03672; hypothetical protein complement(1707709..1707957) Streptococcus pneumoniae Taiwan19F-14 7686333 YP_002743185.1 CDS SPT_1800 NC_012469.1 1708213 1709838 R identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403; trehalose-6-phosphate hydrolase complement(1708213..1709838) Streptococcus pneumoniae Taiwan19F-14 7687238 YP_002743186.1 CDS treP NC_012469.1 1710016 1711983 R identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR01992; pts system, trehalose-specific iibc component complement(1710016..1711983) Streptococcus pneumoniae Taiwan19F-14 7686329 YP_002743187.1 CDS treR NC_012469.1 1712168 1712878 D identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02404; trehalose operon repressor 1712168..1712878 Streptococcus pneumoniae Taiwan19F-14 7686736 YP_002743188.1 CDS SPT_1809 NC_012469.1 1716144 1717070 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; oligopeptide transport ATP-binding protein AmiF complement(1716144..1717070) Streptococcus pneumoniae Taiwan19F-14 7686553 YP_002743189.1 CDS SPT_1810 NC_012469.1 1717081 1718148 R identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727; oligopeptide transport ATP-binding protein OppD complement(1717081..1718148) Streptococcus pneumoniae Taiwan19F-14 7687011 YP_002743190.1 CDS SPT_1811 NC_012469.1 1718157 1719083 R identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AmiD complement(1718157..1719083) Streptococcus pneumoniae Taiwan19F-14 7685238 YP_002743191.1 CDS SPT_1812 NC_012469.1 1719083 1720579 R identified by match to protein family HMM PF00528; oligopeptide transport system permease protein AmiC complement(1719083..1720579) Streptococcus pneumoniae Taiwan19F-14 7685377 YP_002743192.1 CDS SPT_1813 NC_012469.1 1720646 1722625 R identified by match to protein family HMM PF00496; AmiA protein complement(1720646..1722625) Streptococcus pneumoniae Taiwan19F-14 7685252 YP_002743193.1 CDS SPT_1814 NC_012469.1 1723311 1724504 R identified by match to protein family HMM PF04932; O-antigen polymerase family complement(1723311..1724504) Streptococcus pneumoniae Taiwan19F-14 7685292 YP_002743194.1 CDS SPT_1815 NC_012469.1 1724642 1726084 R identified by match to protein family HMM PF00128; sucrose phosphorylase (Sucrose glucosyltransferase)(Glucosyltransferase-A) (GTF-A) complement(1724642..1726084) Streptococcus pneumoniae Taiwan19F-14 7686799 YP_002743195.1 CDS SPT_1816 NC_012469.1 1726295 1726435 R chlorohydrolase complement(1726295..1726435) Streptococcus pneumoniae Taiwan19F-14 7685787 YP_002743196.1 CDS SPT_1817 NC_012469.1 1726442 1727275 R identified by match to protein family HMM PF00528; sugar ABC transporter permease complement(1726442..1727275) Streptococcus pneumoniae Taiwan19F-14 7686870 YP_002743197.1 CDS SPT_1818 NC_012469.1 1727289 1728155 R identified by match to protein family HMM PF00528; sugar ABC transporter permease complement(1727289..1728155) Streptococcus pneumoniae Taiwan19F-14 7686192 YP_002743198.1 CDS SPT_1819 NC_012469.1 1728169 1729428 R identified by match to protein family HMM PF01547; sugar ABC transporter substrate-binding protein complement(1728169..1729428) Streptococcus pneumoniae Taiwan19F-14 7687240 YP_002743199.1 CDS SPT_1821 NC_012469.1 1729520 1731682 R identified by match to protein family HMM PF02065; alpha-galactosidase (Melibiase) complement(1729520..1731682) Streptococcus pneumoniae Taiwan19F-14 7685899 YP_002743200.1 CDS SPT_1822 NC_012469.1 1731790 1732650 D identified by match to protein family HMM PF00165; match to protein family HMM PF02311; Msm operon regulatory protein 1731790..1732650 Streptococcus pneumoniae Taiwan19F-14 7685531 YP_002743201.1 CDS SPT_1823 NC_012469.1 1732647 1733582 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1732647..1733582 Streptococcus pneumoniae Taiwan19F-14 7686811 YP_002743202.1 CDS rumA2 NC_012469.1 1740485 1741840 R identified by match to protein family HMM PF01938; match to protein family HMM PF05958; match to protein family HMM TIGR00479; 23S rRNA (uracil-5-)-methyltransferase RumA complement(1740485..1741840) Streptococcus pneumoniae Taiwan19F-14 7685581 YP_002743203.1 CDS recX NC_012469.1 1741878 1742654 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1741878..1742654 Streptococcus pneumoniae Taiwan19F-14 7687350 YP_002743204.1 CDS SPT_1848 NC_012469.1 1742743 1743276 D identified by match to protein family HMM PF04167; hypothetical protein 1742743..1743276 Streptococcus pneumoniae Taiwan19F-14 7685794 YP_002743205.1 CDS SPT_1849 NC_012469.1 1743631 1743837 R hypothetical protein complement(1743631..1743837) Streptococcus pneumoniae Taiwan19F-14 7685287 YP_002743206.1 CDS SPT_1851 NC_012469.1 1744499 1745272 R identified by match to protein family HMM PF08241; match to protein family HMM PF08242; MerR-family transcriptional regulator complement(1744499..1745272) Streptococcus pneumoniae Taiwan19F-14 7685227 YP_002743207.1 CDS SPT_1852 NC_012469.1 1745345 1745464 D an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1745345..1745464 Streptococcus pneumoniae Taiwan19F-14 7685300 YP_002743208.1 CDS groEL NC_012469.1 1746613 1748235 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(1746613..1748235) Streptococcus pneumoniae Taiwan19F-14 7686570 YP_002743209.1 CDS groES NC_012469.1 1748251 1748535 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1748251..1748535) Streptococcus pneumoniae Taiwan19F-14 7685519 YP_002743210.1 CDS SPT_1857 NC_012469.1 1748691 1749086 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1748691..1749086) Streptococcus pneumoniae Taiwan19F-14 7685402 YP_002743211.1 CDS SPT_1858 NC_012469.1 1749164 1749925 R identified by match to protein family HMM PF00106; match to protein family HMM PF08659; oxidoreductase, short chain dehydrogenase/reductase family complement(1749164..1749925) Streptococcus pneumoniae Taiwan19F-14 7686412 YP_002743212.1 CDS SPT_1859 NC_012469.1 1749958 1750584 R identified by match to protein family HMM PF01588; putative tRNA binding domain protein complement(1749958..1750584) Streptococcus pneumoniae Taiwan19F-14 7687180 YP_002743213.1 CDS SPT_1860 NC_012469.1 1750600 1750917 R identified by match to protein family HMM PF00085; thioredoxin family protein complement(1750600..1750917) Streptococcus pneumoniae Taiwan19F-14 7685342 YP_002743214.1 CDS SPT_1861 NC_012469.1 1750914 1751213 R hypothetical protein complement(1750914..1751213) Streptococcus pneumoniae Taiwan19F-14 7686043 YP_002743215.1 CDS SPT_1862 NC_012469.1 1751307 1751438 D identified by glimmer; putative; hypothetical protein 1751307..1751438 Streptococcus pneumoniae Taiwan19F-14 7686028 YP_002743216.1 CDS SPT_1863 NC_012469.1 1751463 1751588 R identified by match to protein family HMM PF01473; choline binding protein G complement(1751463..1751588) Streptococcus pneumoniae Taiwan19F-14 7686654 YP_002743217.1 CDS SPT_1864 NC_012469.1 1751903 1752577 R hypothetical protein complement(1751903..1752577) Streptococcus pneumoniae Taiwan19F-14 7685871 YP_002743218.1 CDS SPT_1865 NC_012469.1 1752582 1753028 R identified by match to protein family HMM PF04397; response regulator of the LytR/AlgR family complement(1752582..1753028) Streptococcus pneumoniae Taiwan19F-14 7685496 YP_002743219.1 CDS SPT_1866 NC_012469.1 1753142 1753645 R identified by match to protein family HMM PF01569; PAP2 family protein complement(1753142..1753645) Streptococcus pneumoniae Taiwan19F-14 7685460 YP_002743220.1 CDS SPT_1867 NC_012469.1 1753642 1754004 R hypothetical protein complement(1753642..1754004) Streptococcus pneumoniae Taiwan19F-14 7686900 YP_002743221.1 CDS SPT_1868 NC_012469.1 1754070 1755101 R identified by match to protein family HMM PF00005; multidrug resistance protein 3 (P-glycoprotein C) complement(1754070..1755101) Streptococcus pneumoniae Taiwan19F-14 7687155 YP_002743222.1 CDS SPT_1869 NC_012469.1 1755108 1755929 R identified by match to protein family HMM PF00664; ABC transporter permease complement(1755108..1755929) Streptococcus pneumoniae Taiwan19F-14 7687345 YP_002743223.1 CDS SPT_1870 NC_012469.1 1756047 1756418 R identified by match to protein family HMM PF01047; transcriptional regulator, MarR family complement(1756047..1756418) Streptococcus pneumoniae Taiwan19F-14 7685862 YP_002743224.1 CDS SPT_1871 NC_012469.1 1756542 1757258 R identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein complement(1756542..1757258) Streptococcus pneumoniae Taiwan19F-14 7686539 YP_002743225.1 CDS SPT_1872 NC_012469.1 1758139 1759554 R identified by match to protein family HMM PF01289; pneumolysin (Thiol-activated cytolysin) complement(1758139..1759554) Streptococcus pneumoniae Taiwan19F-14 7685631 YP_002743226.1 CDS SPT_1873 NC_012469.1 1759565 1759897 R hypothetical protein complement(1759565..1759897) Streptococcus pneumoniae Taiwan19F-14 7685699 YP_002743227.1 CDS SPT_1874 NC_012469.1 1759968 1760576 R hypothetical protein complement(1759968..1760576) Streptococcus pneumoniae Taiwan19F-14 7686928 YP_002743228.1 CDS SPT_1875 NC_012469.1 1760589 1761047 R hypothetical protein complement(1760589..1761047) Streptococcus pneumoniae Taiwan19F-14 7687109 YP_002743229.1 CDS SPT_1876 NC_012469.1 1761172 1761303 D mobile genetic element 1761172..1761303 Streptococcus pneumoniae Taiwan19F-14 7686459 YP_002743230.1 CDS SPT_1877 NC_012469.1 1761308 1761571 D mobile genetic element 1761308..1761571 Streptococcus pneumoniae Taiwan19F-14 7685987 YP_002743231.1 CDS SPT_1878 NC_012469.1 1762048 1762881 D identified by glimmer; putative; hypothetical protein 1762048..1762881 Streptococcus pneumoniae Taiwan19F-14 7686160 YP_002743232.1 CDS SPT_1879 NC_012469.1 1762908 1763969 D ABC transporter substrate-binding protein 1762908..1763969 Streptococcus pneumoniae Taiwan19F-14 7686529 YP_002743233.1 CDS SPT_1880 NC_012469.1 1763986 1764990 D identified by match to protein family HMM PF00005; spermidine/putrescine import ATP-binding protein PotA 1763986..1764990 Streptococcus pneumoniae Taiwan19F-14 7685743 YP_002743234.1 CDS SPT_1884 NC_012469.1 1767445 1768044 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; hydrolase 1767445..1768044 Streptococcus pneumoniae Taiwan19F-14 7685445 YP_002743235.1 CDS SPT_1885 NC_012469.1 1768054 1770081 D identified by match to protein family HMM PF00356; transcriptional regulator, LacI family protein 1768054..1770081 Streptococcus pneumoniae Taiwan19F-14 7685303 YP_002743236.1 CDS SPT_1886 NC_012469.1 1770240 1770371 D mobile genetic element 1770240..1770371 Streptococcus pneumoniae Taiwan19F-14 7685478 YP_002743237.1 CDS SPT_1887 NC_012469.1 1770376 1770639 D mobile genetic element 1770376..1770639 Streptococcus pneumoniae Taiwan19F-14 7686358 YP_002743238.1 CDS SPT_1888 NC_012469.1 1771377 1771637 R hypothetical protein complement(1771377..1771637) Streptococcus pneumoniae Taiwan19F-14 7686542 YP_002743239.1 CDS SPT_1889 NC_012469.1 1771696 1772247 R hypothetical protein complement(1771696..1772247) Streptococcus pneumoniae Taiwan19F-14 7686545 YP_002743240.1 CDS SPT_1890 NC_012469.1 1772237 1772434 R hypothetical protein complement(1772237..1772434) Streptococcus pneumoniae Taiwan19F-14 7687206 YP_002743241.1 CDS SPT_1891 NC_012469.1 1772438 1773232 R hypothetical protein complement(1772438..1773232) Streptococcus pneumoniae Taiwan19F-14 7685272 YP_002743242.1 CDS SPT_1892 NC_012469.1 1773640 1774065 R hypothetical protein complement(1773640..1774065) Streptococcus pneumoniae Taiwan19F-14 7685510 YP_002743243.1 CDS SPT_1893 NC_012469.1 1774194 1774553 R identified by glimmer; putative; hypothetical protein complement(1774194..1774553) Streptococcus pneumoniae Taiwan19F-14 7686198 YP_002743244.1 CDS SPT_1894 NC_012469.1 1774792 1774953 R type II restriction-modification system regulatory protein, putative complement(1774792..1774953) Streptococcus pneumoniae Taiwan19F-14 7685844 YP_002743245.1 CDS SPT_1895 NC_012469.1 1775312 1776268 R identified by match to protein family HMM PF01473; match to protein family HMM PF01510; autolysin (N-acetylmuramoyl-L-alanine amidase) (Mureinhydrolase) (Mucopeptide aminohydrolase) (Cell wall hydrolase) complement(1775312..1776268) Streptococcus pneumoniae Taiwan19F-14 7687253 YP_002743246.1 CDS SPT_1896 NC_012469.1 1776396 1776509 R identified by glimmer; putative; hypothetical protein complement(1776396..1776509) Streptococcus pneumoniae Taiwan19F-14 7685769 YP_002743247.1 CDS SPT_1897 NC_012469.1 1776644 1778014 R identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible protein complement(1776644..1778014) Streptococcus pneumoniae Taiwan19F-14 7687015 YP_002743248.1 CDS recA NC_012469.1 1778321 1779487 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1778321..1779487) Streptococcus pneumoniae Taiwan19F-14 7686410 YP_002743249.1 CDS SPT_1899 NC_012469.1 1779542 1780798 R identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; competence damage-inducible protein A complement(1779542..1780798) Streptococcus pneumoniae Taiwan19F-14 7687088 YP_002743250.1 CDS SPT_1900 NC_012469.1 1780883 1781899 R identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; regulator of lytrabc operon complement(1780883..1781899) Streptococcus pneumoniae Taiwan19F-14 7687044 YP_002743251.1 CDS SPT_1901 NC_012469.1 1781907 1782425 R identified by match to protein family HMM PF00583; acetyltransferase, gnat family complement(1781907..1782425) Streptococcus pneumoniae Taiwan19F-14 7687261 YP_002743252.1 CDS SPT_1902 NC_012469.1 1782415 1782858 R identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein complement(1782415..1782858) Streptococcus pneumoniae Taiwan19F-14 7686262 YP_002743253.1 CDS SPT_1903 NC_012469.1 1782944 1783564 R lipoprotein, putative complement(1782944..1783564) Streptococcus pneumoniae Taiwan19F-14 7686556 YP_002743254.1 CDS SPT_1904 NC_012469.1 1783870 1784733 R identified by match to protein family HMM PF01381; transcriptional activator complement(1783870..1784733) Streptococcus pneumoniae Taiwan19F-14 7686453 YP_002743255.1 CDS SPT_1905 NC_012469.1 1784924 1785094 D hypothetical protein 1784924..1785094 Streptococcus pneumoniae Taiwan19F-14 7686766 YP_002743256.1 CDS SPT_1906 NC_012469.1 1785354 1785473 D identified by glimmer; putative; hypothetical protein 1785354..1785473 Streptococcus pneumoniae Taiwan19F-14 7686422 YP_002743257.1 CDS SPT_1907 NC_012469.1 1785496 1785810 D identified by match to protein family HMM PF06125; conjugative transposon protein 1785496..1785810 Streptococcus pneumoniae Taiwan19F-14 7685728 YP_002743258.1 CDS SPT_1908 NC_012469.1 1785829 1786212 D identified by match to protein family HMM PF06125; conjugative transposon protein 1785829..1786212 Streptococcus pneumoniae Taiwan19F-14 7686036 YP_002743259.1 CDS SPT_1909 NC_012469.1 1786241 1787626 D identified by match to protein family HMM PF01580; ftsk/spoiiie family protein 1786241..1787626 Streptococcus pneumoniae Taiwan19F-14 7686874 YP_002743260.1 CDS SPT_1910 NC_012469.1 1787804 1789009 D identified by match to protein family HMM PF01381; match to protein family HMM PF02486; transcriptional regulator, Cro/CI family 1787804..1789009 Streptococcus pneumoniae Taiwan19F-14 7687098 YP_002743261.1 CDS SPT_1911 NC_012469.1 1789052 1789273 D hypothetical protein 1789052..1789273 Streptococcus pneumoniae Taiwan19F-14 7685447 YP_002743262.1 CDS SPT_1912 NC_012469.1 1789390 1789887 D identified by match to protein family HMM PF07275; conjugative transposon protein 1789390..1789887 Streptococcus pneumoniae Taiwan19F-14 7686699 YP_002743263.1 CDS SPT_1913 NC_012469.1 1789862 1790368 D conjugative transposon membrane protein 1789862..1790368 Streptococcus pneumoniae Taiwan19F-14 7687290 YP_002743264.1 CDS SPT_1914 NC_012469.1 1790352 1792799 D conjugative transposon protein 1790352..1792799 Streptococcus pneumoniae Taiwan19F-14 7685397 YP_002743265.1 CDS SPT_1915 NC_012469.1 1792802 1794979 D conjugative transposon membrane protein 1792802..1794979 Streptococcus pneumoniae Taiwan19F-14 7685240 YP_002743266.1 CDS SPT_1916 NC_012469.1 1794976 1795977 D identified by match to protein family HMM PF00877; NLP/P60 family protein 1794976..1795977 Streptococcus pneumoniae Taiwan19F-14 7685314 YP_002743267.1 CDS SPT_1917 NC_012469.1 1795974 1796906 D conjugative transposon protein 1795974..1796906 Streptococcus pneumoniae Taiwan19F-14 7686810 YP_002743268.1 CDS SPT_1918 NC_012469.1 1797181 1797267 D regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide 1797181..1797267 Streptococcus pneumoniae Taiwan19F-14 7687281 YP_002743269.1 CDS SPT_1919 NC_012469.1 1797283 1799202 D identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231; tetracycline resistance protein 1797283..1799202 Streptococcus pneumoniae Taiwan19F-14 7687252 YP_002743270.1 CDS SPT_1922 NC_012469.1 1799808 1800143 D hypothetical protein 1799808..1800143 Streptococcus pneumoniae Taiwan19F-14 7686046 YP_002743271.1 CDS SPT_1923 NC_012469.1 1800213 1800524 D hypothetical protein 1800213..1800524 Streptococcus pneumoniae Taiwan19F-14 7686913 YP_002743272.1 CDS SPT_1924 NC_012469.1 1800511 1800810 D hypothetical protein 1800511..1800810 Streptococcus pneumoniae Taiwan19F-14 7686263 YP_002743273.1 CDS SPT_1925 NC_012469.1 1800928 1802391 R identified by match to protein family HMM PF00005; Mel protein complement(1800928..1802391) Streptococcus pneumoniae Taiwan19F-14 7685970 YP_002743274.1 CDS SPT_1926 NC_012469.1 1802511 1803728 R identified by match to protein family HMM PF07690; match to protein family HMM TIGR00900; macrolide-efflux protein complement(1802511..1803728) Streptococcus pneumoniae Taiwan19F-14 7685502 YP_002743275.1 CDS SPT_1927 NC_012469.1 1804114 1804284 R hypothetical protein complement(1804114..1804284) Streptococcus pneumoniae Taiwan19F-14 7686216 YP_002743276.1 CDS SPT_1928 NC_012469.1 1805057 1805410 R identified by match to protein family HMM PF01381; transcriptional regulator, putative complement(1805057..1805410) Streptococcus pneumoniae Taiwan19F-14 7687105 YP_002743277.1 CDS SPT_1929 NC_012469.1 1805915 1806337 D identified by match to protein family HMM PF04545; match to protein family HMM PF08281; sigma-70, region 4 family 1805915..1806337 Streptococcus pneumoniae Taiwan19F-14 7686843 YP_002743278.1 CDS SPT_1930 NC_012469.1 1807025 1807228 D identified by match to protein family HMM PF09035; hypothetical protein 1807025..1807228 Streptococcus pneumoniae Taiwan19F-14 7687192 YP_002743279.1 CDS SPT_1931 NC_012469.1 1807310 1808527 D identified by match to protein family HMM PF00589; match to protein family HMM PF02920; transposase 1807310..1808527 Streptococcus pneumoniae Taiwan19F-14 7686825 YP_002743280.1 CDS SPT_1932 NC_012469.1 1808877 1809017 D identified by glimmer; putative; hypothetical protein 1808877..1809017 Streptococcus pneumoniae Taiwan19F-14 7685968 YP_002743281.1 CDS SPT_1933 NC_012469.1 1809418 1811433 D identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; bacteriocin-associated integral membrane protein 1809418..1811433 Streptococcus pneumoniae Taiwan19F-14 7685745 YP_002743282.1 CDS SPT_1934 NC_012469.1 1811435 1812067 D identified by match to protein family HMM PF00005; antimicrobial peptide ABC transporter ATPase 1811435..1812067 Streptococcus pneumoniae Taiwan19F-14 7686203 YP_002743283.1 CDS SPT_1935 NC_012469.1 1812208 1812369 D hypothetical protein 1812208..1812369 Streptococcus pneumoniae Taiwan19F-14 7686850 YP_002743284.1 CDS ndk NC_012469.1 1812995 1813408 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1812995..1813408) Streptococcus pneumoniae Taiwan19F-14 7686298 YP_002743285.1 CDS rpoC NC_012469.1 1813519 1817196 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1813519..1817196) Streptococcus pneumoniae Taiwan19F-14 7686821 YP_002743286.1 CDS rpoB NC_012469.1 1817229 1820840 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1817229..1820840) Streptococcus pneumoniae Taiwan19F-14 7686402 YP_002743287.1 CDS SPT_1939 NC_012469.1 1820969 1821085 D identified by glimmer; putative; hypothetical protein 1820969..1821085 Streptococcus pneumoniae Taiwan19F-14 7685439 YP_002743288.1 CDS SPT_1941 NC_012469.1 1821343 1821462 R identified by glimmer; putative; hypothetical protein complement(1821343..1821462) Streptococcus pneumoniae Taiwan19F-14 7685601 YP_002743289.1 CDS SPT_1942 NC_012469.1 1821524 1822855 R identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain protein complement(1821524..1822855) Streptococcus pneumoniae Taiwan19F-14 7685754 YP_002743290.1 CDS SPT_1943 NC_012469.1 1823146 1823970 R identified by match to protein family HMM PF01223; DNA-entry nuclease (Competence-specific nuclease) complement(1823146..1823970) Streptococcus pneumoniae Taiwan19F-14 7685921 YP_002743291.1 CDS SPT_1944 NC_012469.1 1824009 1824197 R hypothetical protein complement(1824009..1824197) Streptococcus pneumoniae Taiwan19F-14 7685886 YP_002743292.1 CDS murA NC_012469.1 1824190 1825473 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1824190..1825473) Streptococcus pneumoniae Taiwan19F-14 7686749 YP_002743293.1 CDS SPT_1946 NC_012469.1 1825497 1825628 R hypothetical protein complement(1825497..1825628) Streptococcus pneumoniae Taiwan19F-14 7685680 YP_002743294.1 CDS SPT_1947 NC_012469.1 1825785 1826822 R ATP-dependent protease La complement(1825785..1826822) Streptococcus pneumoniae Taiwan19F-14 7687124 YP_002743295.1 CDS coaD NC_012469.1 1826806 1827294 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1826806..1827294) Streptococcus pneumoniae Taiwan19F-14 7686705 YP_002743296.1 CDS rsmD NC_012469.1 1827284 1827823 R identified by match to protein family HMM PF03602; match to protein family HMM TIGR00095; RNA methyltransferase, RsmD family complement(1827284..1827823) Streptococcus pneumoniae Taiwan19F-14 7685474 YP_002743297.1 CDS asnA NC_012469.1 1827888 1828880 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(1827888..1828880) Streptococcus pneumoniae Taiwan19F-14 7686487 YP_002743298.1 CDS SPT_1951 NC_012469.1 1828854 1828985 D identified by glimmer; putative; hypothetical protein 1828854..1828985 Streptococcus pneumoniae Taiwan19F-14 7686181 YP_002743299.1 CDS SPT_1952 NC_012469.1 1828991 1829674 R identified by match to protein family HMM PF01027; membrane protein complement(1828991..1829674) Streptococcus pneumoniae Taiwan19F-14 7686108 YP_002743300.1 CDS SPT_1953 NC_012469.1 1829730 1830470 R identified by match to protein family HMM PF00588; match to protein family HMM PF08032; SpoU rRNA Methylase family protein complement(1829730..1830470) Streptococcus pneumoniae Taiwan19F-14 7686309 YP_002743301.1 CDS SPT_1954 NC_012469.1 1830504 1830782 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1830504..1830782 Streptococcus pneumoniae Taiwan19F-14 7686939 YP_002743302.1 CDS SPT_1955 NC_012469.1 1830860 1831786 D involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1830860..1831786 Streptococcus pneumoniae Taiwan19F-14 7685285 YP_002743303.1 CDS pflA NC_012469.1 1831861 1832655 R identified by match to protein family HMM PF04055; match to protein family HMM TIGR02493; pyruvate formate-lyase 1-activating enzyme complement(1831861..1832655) Streptococcus pneumoniae Taiwan19F-14 7685775 YP_002743304.1 CDS SPT_1957 NC_012469.1 1832781 1834031 R identified by match to protein family HMM PF00278; match to protein family HMM PF02784; diaminopimelate decarboxylase complement(1832781..1834031) Streptococcus pneumoniae Taiwan19F-14 7686045 YP_002743305.1 CDS purR NC_012469.1 1834098 1834925 R identified by match to protein family HMM PF00156; match to protein family HMM PF09182; match to protein family HMM TIGR01743; pur operon repressor complement(1834098..1834925) Streptococcus pneumoniae Taiwan19F-14 7686901 YP_002743306.1 CDS SPT_1959 NC_012469.1 1835192 1836133 R identified by match to protein family HMM PF01336; match to protein family HMM PF01966; 3'-5' exoribonuclease YhaM complement(1835192..1836133) Streptococcus pneumoniae Taiwan19F-14 7687107 YP_002743307.1 CDS SPT_1960 NC_012469.1 1836123 1837379 R identified by match to protein family HMM PF02646; competence-induced protein Ccs50 complement(1836123..1837379) Streptococcus pneumoniae Taiwan19F-14 7686520 YP_002743308.1 CDS SPT_1961 NC_012469.1 1837381 1838043 R identified by match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378; thiamine pyrophosphokinase complement(1837381..1838043) Streptococcus pneumoniae Taiwan19F-14 7686225 YP_002743309.1 CDS rpe NC_012469.1 1838006 1838662 R identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase complement(1838006..1838662) Streptococcus pneumoniae Taiwan19F-14 7686171 YP_002743310.1 CDS rsgA NC_012469.1 1838673 1839551 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1838673..1839551) Streptococcus pneumoniae Taiwan19F-14 7686450 YP_002743311.1 CDS ksgA NC_012469.1 1839553 1840425 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1839553..1840425) Streptococcus pneumoniae Taiwan19F-14 7686370 YP_002743312.1 CDS SPT_1965 NC_012469.1 1840676 1840792 R identified by glimmer; putative; hypothetical protein complement(1840676..1840792) Streptococcus pneumoniae Taiwan19F-14 7686961 YP_002743313.1 CDS SPT_1966 NC_012469.1 1840811 1840969 R identified by glimmer; putative; hypothetical protein complement(1840811..1840969) Streptococcus pneumoniae Taiwan19F-14 7686109 YP_002743314.1 CDS SPT_1967 NC_012469.1 1840962 1841603 R identified by match to protein family HMM PF00005; antimicrobial peptide ABC transporter ATPase complement(1840962..1841603) Streptococcus pneumoniae Taiwan19F-14 7685835 YP_002743315.1 CDS SPT_1968 NC_012469.1 1841605 1843635 R identified by match to protein family HMM PF07242; match to protein family HMM TIGR01654; immunity protein, putative complement(1841605..1843635) Streptococcus pneumoniae Taiwan19F-14 7685836 YP_002743316.1 CDS SPT_1969 NC_012469.1 1843903 1844802 R transcriptional activator complement(1843903..1844802) Streptococcus pneumoniae Taiwan19F-14 7686505 YP_002743317.1 CDS SPT_1970 NC_012469.1 1844874 1845434 R identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; putative primase homolog complement(1844874..1845434) Streptococcus pneumoniae Taiwan19F-14 7687309 YP_002743318.1 CDS SPT_1971 NC_012469.1 1845434 1846207 R identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; putative deoxyribonuclease YcfH complement(1845434..1846207) Streptococcus pneumoniae Taiwan19F-14 7686893 YP_002743319.1 CDS SPT_1972 NC_012469.1 1846512 1847516 R identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167; cell wall surface anchor family protein complement(1846512..1847516) Streptococcus pneumoniae Taiwan19F-14 7686597 YP_002743320.1 CDS rpmH NC_012469.1 1847689 1847823 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1847689..1847823) Streptococcus pneumoniae Taiwan19F-14 7686748 YP_002743321.1 CDS SPT_1974 NC_012469.1 1847968 1849182 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(1847968..1849182) Streptococcus pneumoniae Taiwan19F-14 7685426 YP_002743322.1 CDS SPT_1975 NC_012469.1 1849373 1849630 R identified by glimmer; putative; hypothetical protein complement(1849373..1849630) Streptococcus pneumoniae Taiwan19F-14 7686346 YP_002743323.1 CDS SPT_1976 NC_012469.1 1849792 1850244 D identified by match to protein family HMM PF00582; universal stress protein family 1849792..1850244 Streptococcus pneumoniae Taiwan19F-14 7685705 YP_002743324.1 CDS SPT_1977 NC_012469.1 1850279 1851667 R identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; Cof family protein complement(1850279..1851667) Streptococcus pneumoniae Taiwan19F-14 7685513 YP_002743325.1 CDS SPT_1978 NC_012469.1 1851733 1852695 D identified by match to protein family HMM PF00710; L-asparaginase 1851733..1852695 Streptococcus pneumoniae Taiwan19F-14 7685419 YP_002743326.1 CDS SPT_1979 NC_012469.1 1852724 1852972 R identified by glimmer; putative; hypothetical protein complement(1852724..1852972) Streptococcus pneumoniae Taiwan19F-14 7686414 YP_002743327.1 CDS ccpA NC_012469.1 1853036 1854046 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481; catabolite control protein A complement(1853036..1854046) Streptococcus pneumoniae Taiwan19F-14 7685361 YP_002743328.1 CDS SPT_1981 NC_012469.1 1854471 1855070 R identified by match to protein family HMM PF00072; match to protein family HMM PF00196; response regulator complement(1854471..1855070) Streptococcus pneumoniae Taiwan19F-14 7685978 YP_002743329.1 CDS SPT_1982 NC_012469.1 1855072 1856169 R identified by match to protein family HMM PF02518; match to protein family HMM PF07730; histidine kinase complement(1855072..1856169) Streptococcus pneumoniae Taiwan19F-14 7685819 YP_002743330.1 CDS SPT_1983 NC_012469.1 1856169 1856936 R multidrug ABC transporter permease complement(1856169..1856936) Streptococcus pneumoniae Taiwan19F-14 7686537 YP_002743331.1 CDS SPT_1984 NC_012469.1 1856908 1857792 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1856908..1857792) Streptococcus pneumoniae Taiwan19F-14 7687062 YP_002743332.1 CDS SPT_1985 NC_012469.1 1857779 1857973 R hypothetical protein complement(1857779..1857973) Streptococcus pneumoniae Taiwan19F-14 7685633 YP_002743333.1 CDS SPT_1986 NC_012469.1 1857970 1858176 R hypothetical protein complement(1857970..1858176) Streptococcus pneumoniae Taiwan19F-14 7685950 YP_002743334.1 CDS SPT_1987 NC_012469.1 1858649 1859995 D identified by match to protein family HMM PF01609; Spn1 transposase 1858649..1859995 Streptococcus pneumoniae Taiwan19F-14 7685324 YP_002743335.1 CDS SPT_2002 NC_012469.1 1866564 1867043 R competence-specific global transcription modulator complement(1866564..1867043) Streptococcus pneumoniae Taiwan19F-14 7685599 YP_002743336.1 CDS nusG NC_012469.1 1867165 1867701 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1867165..1867701) Streptococcus pneumoniae Taiwan19F-14 7687297 YP_002743337.1 CDS secE NC_012469.1 1867756 1867932 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1867756..1867932) Streptococcus pneumoniae Taiwan19F-14 7686707 YP_002743338.1 CDS rpmG NC_012469.1 1867942 1868094 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 complement(1867942..1868094) Streptococcus pneumoniae Taiwan19F-14 7687076 YP_002743339.1 CDS SPT_2006 NC_012469.1 1868147 1870342 R identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 2A complement(1868147..1870342) Streptococcus pneumoniae Taiwan19F-14 7685945 YP_002743340.1 CDS SPT_2007 NC_012469.1 1870468 1871304 D identified by match to protein family HMM PF00849; ribosomal large subunit pseudouridine synthase, RluD subfamily 1870468..1871304 Streptococcus pneumoniae Taiwan19F-14 7686697 YP_002743341.1 CDS gap NC_012469.1 1871373 1872380 R identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde-3-phosphate dehydrogenase, type I complement(1871373..1872380) Streptococcus pneumoniae Taiwan19F-14 7686485 YP_002743342.1 CDS SPT_2009 NC_012469.1 1872560 1873522 R identified by match to protein family HMM PF02687; efflux ABC transporter, permease protein complement(1872560..1873522) Streptococcus pneumoniae Taiwan19F-14 7686664 YP_002743343.1 CDS SPT_2010 NC_012469.1 1873545 1873673 R identified by glimmer; putative; hypothetical protein complement(1873545..1873673) Streptococcus pneumoniae Taiwan19F-14 7685965 YP_002743344.1 CDS SPT_2011 NC_012469.1 1873813 1874061 D hypothetical protein 1873813..1874061 Streptococcus pneumoniae Taiwan19F-14 7685817 YP_002743345.1 CDS SPT_2012 NC_012469.1 1874100 1874429 R identified by match to protein family HMM PF01710; transposase complement(1874100..1874429) Streptococcus pneumoniae Taiwan19F-14 7686372 YP_002743346.1 CDS nadC NC_012469.1 1874560 1875432 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1874560..1875432) Streptococcus pneumoniae Taiwan19F-14 7686989 YP_002743347.1 CDS SPT_2014 NC_012469.1 1875669 1876979 D identified by match to protein family HMM PF03600; match to protein family HMM PF07158; membrane protein 1875669..1876979 Streptococcus pneumoniae Taiwan19F-14 7686616 YP_002743348.1 CDS SPT_2015 NC_012469.1 1877345 1877476 R hypothetical protein complement(1877345..1877476) Streptococcus pneumoniae Taiwan19F-14 7685650 YP_002743349.1 CDS SPT_2016 NC_012469.1 1877999 1878727 R identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator complement(1877999..1878727) Streptococcus pneumoniae Taiwan19F-14 7687012 YP_002743350.1 CDS SPT_2017 NC_012469.1 1878885 1880294 D identified by match to protein family HMM PF00232; beta-glucosidase 1878885..1880294 Streptococcus pneumoniae Taiwan19F-14 7687386 YP_002743351.1 CDS SPT_2018 NC_012469.1 1880312 1881607 D identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410; phosphotransferase system system, cellobiose-specific IIC component 1880312..1881607 Streptococcus pneumoniae Taiwan19F-14 7686313 YP_002743352.1 CDS SPT_2019 NC_012469.1 1881612 1881920 D identified by match to protein family HMM PF02302; lichenan-specific phosphotransferase enzyme iib component (pts system lichenan-specific eiib component) (eiib-lic) 1881612..1881920 Streptococcus pneumoniae Taiwan19F-14 7685977 YP_002743353.1 CDS SPT_2020 NC_012469.1 1881917 1882225 D identified by match to protein family HMM PF02255; lichenan-specific phosphotransferase enzyme iia component (pts system lichenan-specific eiia component) (eiia-lic) (eiii-lic) 1881917..1882225 Streptococcus pneumoniae Taiwan19F-14 7685348 YP_002743354.1 CDS SPT_2021 NC_012469.1 1883211 1885862 R identified by match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1883211..1885862) Streptococcus pneumoniae Taiwan19F-14 7687380 YP_002743355.1 CDS SPT_2022 NC_012469.1 1886162 1886572 R identified by match to protein family HMM PF02493; morn motif family protein complement(1886162..1886572) Streptococcus pneumoniae Taiwan19F-14 7687272 YP_002743356.1 CDS SPT_2023 NC_012469.1 1886574 1887002 R identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase complement(1886574..1887002) Streptococcus pneumoniae Taiwan19F-14 7685768 YP_002743357.1 CDS yajC NC_012469.1 1887048 1887347 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(1887048..1887347) Streptococcus pneumoniae Taiwan19F-14 7685207 YP_002743358.1 CDS tkt2 NC_012469.1 1887464 1889440 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1887464..1889440) Streptococcus pneumoniae Taiwan19F-14 7686425 YP_002743359.1 CDS SPT_2026 NC_012469.1 1889554 1890645 R putative L-ascorbate 6-phosphate lactonase complement(1889554..1890645) Streptococcus pneumoniae Taiwan19F-14 7687284 YP_002743360.1 CDS SPT_2027 NC_012469.1 1890757 1892430 R identified by match to protein family HMM PF00874; match to protein family HMM PF08279; transcriptional regulator, BglG family complement(1890757..1892430) Streptococcus pneumoniae Taiwan19F-14 7685751 YP_002743361.1 CDS araD NC_012469.1 1892611 1893315 R catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase complement(1892611..1893315) Streptococcus pneumoniae Taiwan19F-14 7685789 YP_002743362.1 CDS SPT_2029 NC_012469.1 1893317 1894180 R L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase complement(1893317..1894180) Streptococcus pneumoniae Taiwan19F-14 7687051 YP_002743363.1 CDS ulaD NC_012469.1 1894184 1894849 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1894184..1894849) Streptococcus pneumoniae Taiwan19F-14 7685209 YP_002743364.1 CDS SPT_2031 NC_012469.1 1894866 1895351 R identified by match to protein family HMM PF00359; ascorbate-specific phosphotransferase enzyme iia component (pts system ascorbate-specific eiia component) complement(1894866..1895351) Streptococcus pneumoniae Taiwan19F-14 7686615 YP_002743365.1 CDS SPT_2032 NC_012469.1 1895427 1895708 R identified by match to protein family HMM PF02302; ascorbate-specific phosphotransferase enzyme iib component (ascorbate-specific pts system eiib component) complement(1895427..1895708) Streptococcus pneumoniae Taiwan19F-14 7685672 YP_002743366.1 CDS SPT_2033 NC_012469.1 1895731 1897188 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(1895731..1897188) Streptococcus pneumoniae Taiwan19F-14 7686337 YP_002743367.1 CDS SPT_2034 NC_012469.1 1897317 1897940 R hypothetical protein complement(1897317..1897940) Streptococcus pneumoniae Taiwan19F-14 7687352 YP_002743368.1 CDS SPT_2035 NC_012469.1 1897991 1898977 R identified by match to protein family HMM PF01424; jag protein complement(1897991..1898977) Streptococcus pneumoniae Taiwan19F-14 7685923 YP_002743369.1 CDS SPT_2036 NC_012469.1 1898996 1899769 R identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592; membrane protein OxaA 1 complement(1898996..1899769) Streptococcus pneumoniae Taiwan19F-14 7685709 YP_002743370.1 CDS rnpA NC_012469.1 1899795 1900166 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(1899795..1900166) Streptococcus pneumoniae Taiwan19F-14 7687241 YP_002743371.1 CDS SPT_2038 NC_012469.1 1900183 1900314 R hypothetical protein complement(1900183..1900314) Streptococcus pneumoniae Taiwan19F-14 7686244 YP_002743372.1 CDS ackA NC_012469.1 1900315 1901505 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1900315..1901505) Streptococcus pneumoniae Taiwan19F-14 7686115 YP_002743373.1 CDS SPT_2040 NC_012469.1 1901556 1902509 R adenine-specific DNA methylase complement(1901556..1902509) Streptococcus pneumoniae Taiwan19F-14 7686427 YP_002743374.1 CDS SPT_2041 NC_012469.1 1902570 1903157 R identified by match to protein family HMM PF01209; match to protein family HMM PF05175; match to protein family HMM PF08241; match to protein family HMM PF08242; methyltransferase small domain superfamily complement(1902570..1903157) Streptococcus pneumoniae Taiwan19F-14 7687239 YP_002743375.1 CDS SPT_2042 NC_012469.1 1903294 1903707 R hypothetical protein complement(1903294..1903707) Streptococcus pneumoniae Taiwan19F-14 7686625 YP_002743376.1 CDS SPT_2043 NC_012469.1 1903685 1904146 R competence protein ComGF complement(1903685..1904146) Streptococcus pneumoniae Taiwan19F-14 7686022 YP_002743377.1 CDS SPT_2044 NC_012469.1 1904109 1904369 R hypothetical protein complement(1904109..1904369) Streptococcus pneumoniae Taiwan19F-14 7687046 YP_002743378.1 CDS SPT_2045 NC_012469.1 1904374 1904778 R identified by match to protein family HMM TIGR02532; competence protein CglD complement(1904374..1904778) Streptococcus pneumoniae Taiwan19F-14 7687127 YP_002743379.1 CDS SPT_2046 NC_012469.1 1904771 1905097 R identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532; competence protein complement(1904771..1905097) Streptococcus pneumoniae Taiwan19F-14 7686604 YP_002743380.1 CDS SPT_2047 NC_012469.1 1905099 1905971 R identified by match to protein family HMM PF00482; competence protein CglB complement(1905099..1905971) Streptococcus pneumoniae Taiwan19F-14 7685690 YP_002743381.1 CDS SPT_2048 NC_012469.1 1906063 1907004 R identified by match to protein family HMM PF00437; putative ABC transporter subunit ComYA complement(1906063..1907004) Streptococcus pneumoniae Taiwan19F-14 7686847 YP_002743382.1 CDS SPT_2049 NC_012469.1 1907080 1907445 R identified by match to protein family HMM PF06279; hypothetical protein complement(1907080..1907445) Streptococcus pneumoniae Taiwan19F-14 7685821 YP_002743383.1 CDS SPT_2050 NC_012469.1 1907596 1908654 R identified by match to protein family HMM PF00107; match to protein family HMM PF08240; alcohol dehydrogenase, zinc-containing complement(1907596..1908654) Streptococcus pneumoniae Taiwan19F-14 7686983 YP_002743384.1 CDS nagA NC_012469.1 1908817 1909968 R identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase complement(1908817..1909968) Streptococcus pneumoniae Taiwan19F-14 7686377 YP_002743385.1 CDS SPT_2052 NC_012469.1 1910121 1911938 R identified by match to protein family HMM PF01757; acyltransferase complement(1910121..1911938) Streptococcus pneumoniae Taiwan19F-14 7686301 YP_002743386.1 CDS tgt NC_012469.1 1912039 1913181 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1912039..1913181) Streptococcus pneumoniae Taiwan19F-14 7686074 YP_002743387.1 CDS SPT_2054 NC_012469.1 1913311 1914168 D identified by match to protein family HMM PF06161; hypothetical protein 1913311..1914168 Streptococcus pneumoniae Taiwan19F-14 7686217 YP_002743388.1 CDS pcp2 NC_012469.1 1914196 1914840 R catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase complement(1914196..1914840) Streptococcus pneumoniae Taiwan19F-14 7686511 YP_002743389.1 CDS SPT_2056 NC_012469.1 1914915 1915316 R identified by match to protein family HMM PF06993; hypothetical protein complement(1914915..1915316) Streptococcus pneumoniae Taiwan19F-14 7687301 YP_002743390.1 CDS SPT_2057 NC_012469.1 1915327 1915752 R identified by match to protein family HMM PF01022; match to protein family HMM PF01047; transcriptional regulator, MarR family complement(1915327..1915752) Streptococcus pneumoniae Taiwan19F-14 7686714 YP_002743391.1 CDS SPT_2058 NC_012469.1 1916075 1917217 R identified by match to protein family HMM PF01476; LysM domain-containing protein complement(1916075..1917217) Streptococcus pneumoniae Taiwan19F-14 7686776 YP_002743392.1 CDS SPT_2059 NC_012469.1 1917383 1918003 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD-superfamily hydrolase, subfamily IA, variant 1 complement(1917383..1918003) Streptococcus pneumoniae Taiwan19F-14 7685879 YP_002743393.1 CDS SPT_2060 NC_012469.1 1918007 1919287 R identified by match to protein family HMM PF01554; match to protein family HMM PF03023; match to protein family HMM TIGR00797; multi antimicrobial extrusion complement(1918007..1919287) Streptococcus pneumoniae Taiwan19F-14 7686371 YP_002743394.1 CDS thrC NC_012469.1 1919348 1920832 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(1919348..1920832) Streptococcus pneumoniae Taiwan19F-14 7685427 YP_002743395.1 CDS SPT_2062 NC_012469.1 1920908 1922185 R hypothetical protein complement(1920908..1922185) Streptococcus pneumoniae Taiwan19F-14 7686837 YP_002743396.1 CDS SPT_2079 NC_012469.1 1928647 1929081 R cytidine/deoxycytidylate deaminase family protein complement(1928647..1929081) Streptococcus pneumoniae Taiwan19F-14 7685586 YP_002743397.1 CDS gltX NC_012469.1 1929095 1930555 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(1929095..1930555) Streptococcus pneumoniae Taiwan19F-14 7687328 YP_002743398.1 CDS pgi NC_012469.1 1930679 1932028 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(1930679..1932028) Streptococcus pneumoniae Taiwan19F-14 7685282 YP_002743399.1 CDS SPT_2082 NC_012469.1 1932015 1932194 R hypothetical protein complement(1932015..1932194) Streptococcus pneumoniae Taiwan19F-14 7686072 YP_002743400.1 CDS SPT_2083 NC_012469.1 1932198 1932887 R identified by match to protein family HMM PF00117; match to protein family HMM PF07722; glutamine amidotransferase complement(1932198..1932887) Streptococcus pneumoniae Taiwan19F-14 7685231 YP_002743401.1 CDS SPT_2084 NC_012469.1 1933026 1934792 R identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease complement(1933026..1934792) Streptococcus pneumoniae Taiwan19F-14 7686669 YP_002743402.1 CDS SPT_2085 NC_012469.1 1934939 1935253 D transposase 1934939..1935253 Streptococcus pneumoniae Taiwan19F-14 7687315 YP_002743403.1 CDS SPT_2086 NC_012469.1 1935584 1937278 R identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease complement(1935584..1937278) Streptococcus pneumoniae Taiwan19F-14 7686431 YP_002743404.1 CDS mutS NC_012469.1 1937424 1939958 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(1937424..1939958) Streptococcus pneumoniae Taiwan19F-14 7686656 YP_002743405.1 CDS argR NC_012469.1 1940009 1940455 R identified by match to protein family HMM PF01316; match to protein family HMM PF02863; match to protein family HMM TIGR01529; arginine repressor complement(1940009..1940455) Streptococcus pneumoniae Taiwan19F-14 7686210 YP_002743406.1 CDS argS NC_012469.1 1940591 1942282 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1940591..1942282 Streptococcus pneumoniae Taiwan19F-14 7685475 YP_002743407.1 CDS SPT_2090 NC_012469.1 1942597 1942986 R identified by match to protein family HMM PF01609; transposase (IS4 family) complement(1942597..1942986) Streptococcus pneumoniae Taiwan19F-14 7685275 YP_002743408.1 CDS SPT_2091 NC_012469.1 1943140 1943625 D identified by match to protein family HMM PF06172; hypothetical protein 1943140..1943625 Streptococcus pneumoniae Taiwan19F-14 7687193 YP_002743409.1 CDS SPT_2092 NC_012469.1 1943709 1944416 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory proteinphoP 1943709..1944416 Streptococcus pneumoniae Taiwan19F-14 7686381 YP_002743410.1 CDS SPT_2093 NC_012469.1 1944417 1945748 D identified by match to protein family HMM PF00512; match to protein family HMM PF02518; histidine kinase PnpS 1944417..1945748 Streptococcus pneumoniae Taiwan19F-14 7686334 YP_002743411.1 CDS SPT_2094 NC_012469.1 1945915 1946790 D ABC transporter substrate-binding protein - phosphate transport 1945915..1946790 Streptococcus pneumoniae Taiwan19F-14 7686911 YP_002743412.1 CDS pstC2 NC_012469.1 1946908 1947771 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 1946908..1947771 Streptococcus pneumoniae Taiwan19F-14 7686044 YP_002743413.1 CDS pstA2 NC_012469.1 1947764 1948579 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 1947764..1948579 Streptococcus pneumoniae Taiwan19F-14 7687104 YP_002743414.1 CDS pstB3 NC_012469.1 1948581 1949333 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1948581..1949333 Streptococcus pneumoniae Taiwan19F-14 7686904 YP_002743415.1 CDS phoU2 NC_012469.1 1949348 1949998 D identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 1949348..1949998 Streptococcus pneumoniae Taiwan19F-14 7685826 YP_002743416.1 CDS SPT_2099 NC_012469.1 1950066 1950491 D transposase, IS1380-Spn1 related, truncation 1950066..1950491 Streptococcus pneumoniae Taiwan19F-14 7686123 YP_002743417.1 CDS gpsA NC_012469.1 1951257 1952273 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1951257..1952273 Streptococcus pneumoniae Taiwan19F-14 7686646 YP_002743418.1 CDS galU NC_012469.1 1952295 1953194 D identified by match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 1952295..1953194 Streptococcus pneumoniae Taiwan19F-14 7687013 YP_002743419.1 CDS SPT_2103 NC_012469.1 1953266 1953943 R identified by match to protein family HMM PF01694; peptidase, S54 complement(1953266..1953943) Streptococcus pneumoniae Taiwan19F-14 7685722 YP_002743420.1 CDS SPT_2104 NC_012469.1 1953927 1954466 R identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; 5-formyltetrahydrofolate cyclo-ligase complement(1953927..1954466) Streptococcus pneumoniae Taiwan19F-14 7686011 YP_002743421.1 CDS SPT_2105 NC_012469.1 1954478 1955608 R identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; peptidase, M20/M25/M40 family complement(1954478..1955608) Streptococcus pneumoniae Taiwan19F-14 7686829 YP_002743422.1 CDS SPT_2106 NC_012469.1 1955676 1956374 R identified by match to protein family HMM PF00132; match to protein family HMM PF08503; galactoside O-acetyltransferase complement(1955676..1956374) Streptococcus pneumoniae Taiwan19F-14 7686777 YP_002743423.1 CDS SPT_2107 NC_012469.1 1956604 1957515 R identified by match to protein family HMM PF00892; membrane protein complement(1956604..1957515) Streptococcus pneumoniae Taiwan19F-14 7685336 YP_002743424.1 CDS SPT_2108 NC_012469.1 1957580 1960045 R identified by match to protein family HMM PF00905; match to protein family HMM PF00912; penicillin-binding protein 1B complement(1957580..1960045) Streptococcus pneumoniae Taiwan19F-14 7686550 YP_002743425.1 CDS tyrS NC_012469.1 1960187 1961443 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1960187..1961443 Streptococcus pneumoniae Taiwan19F-14 7686283 YP_002743426.1 CDS SPT_2110 NC_012469.1 1961521 1963584 R identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01525; P-type ATPase-metal/cation transport complement(1961521..1963584) Streptococcus pneumoniae Taiwan19F-14 7686784 YP_002743427.1 CDS SPT_2111 NC_012469.1 1963586 1963864 R hypothetical protein complement(1963586..1963864) Streptococcus pneumoniae Taiwan19F-14 7685656 YP_002743428.1 CDS SPT_2112 NC_012469.1 1964016 1964864 D identified by match to protein family HMM PF08241; 23S rRNA m1G745 methyltransferase 1964016..1964864 Streptococcus pneumoniae Taiwan19F-14 7686980 YP_002743429.1 CDS SPT_2113 NC_012469.1 1965425 1965631 R identified by glimmer; putative; hypothetical protein complement(1965425..1965631) Streptococcus pneumoniae Taiwan19F-14 7686191 YP_002743430.1 CDS SPT_2114 NC_012469.1 1966586 1968844 R identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093; glycogen phosphorylase complement(1966586..1968844) Streptococcus pneumoniae Taiwan19F-14 7685434 YP_002743431.1 CDS malQ NC_012469.1 1968870 1970387 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(1968870..1970387) Streptococcus pneumoniae Taiwan19F-14 7687214 YP_002743432.1 CDS SPT_2116 NC_012469.1 1970937 1972208 D identified by match to protein family HMM PF01547; maltose/maltodextrin-binding protein 1970937..1972208 Streptococcus pneumoniae Taiwan19F-14 7686304 YP_002743433.1 CDS SPT_2117 NC_012469.1 1972319 1973611 D identified by match to protein family HMM PF00528; match to protein family HMM PF05154; maltodextrin transport system permease protein MalC 1972319..1973611 Streptococcus pneumoniae Taiwan19F-14 7686083 YP_002743434.1 CDS SPT_2118 NC_012469.1 1973613 1974455 D identified by match to protein family HMM PF00528; maltose/maltodextrin ABC transporter permease 1973613..1974455 Streptococcus pneumoniae Taiwan19F-14 7686957 YP_002743435.1 CDS SPT_2119 NC_012469.1 1974708 1975508 D maltodextrose utilization protein MalA 1974708..1975508 Streptococcus pneumoniae Taiwan19F-14 7687148 YP_002743436.1 CDS SPT_2120 NC_012469.1 1975518 1976504 D identified by match to protein family HMM PF00356; match to protein family HMM PF00532; HTH-type transcriptional regulator MalR (Maltose operontranscriptional repressor) 1975518..1976504 Streptococcus pneumoniae Taiwan19F-14 7686906 YP_002743437.1 CDS SPT_2121 NC_012469.1 1976795 1977736 R identified by match to protein family HMM PF02588; YitT family protein complement(1976795..1977736) Streptococcus pneumoniae Taiwan19F-14 7685490 YP_002743438.1 CDS aspS NC_012469.1 1977714 1979477 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1977714..1979477) Streptococcus pneumoniae Taiwan19F-14 7686213 YP_002743439.1 CDS SPT_2123 NC_012469.1 1979596 1979832 R chlorohydrolase complement(1979596..1979832) Streptococcus pneumoniae Taiwan19F-14 7687188 YP_002743440.1 CDS SPT_2124 NC_012469.1 1979874 1980104 R hypothetical protein complement(1979874..1980104) Streptococcus pneumoniae Taiwan19F-14 7685942 YP_002743441.1 CDS SPT_2125 NC_012469.1 1980122 1980763 R identified by match to protein family HMM PF02517; caax amino protease family complement(1980122..1980763) Streptococcus pneumoniae Taiwan19F-14 7686474 YP_002743442.1 CDS SPT_2126 NC_012469.1 1980775 1981509 R hypothetical protein complement(1980775..1981509) Streptococcus pneumoniae Taiwan19F-14 7687313 YP_002743443.1 CDS SPT_2127 NC_012469.1 1981512 1981709 R hypothetical protein complement(1981512..1981709) Streptococcus pneumoniae Taiwan19F-14 7686715 YP_002743444.1 CDS SPT_2128 NC_012469.1 1981709 1981915 R identified by match to protein family HMM PF01381; hypothetical protein complement(1981709..1981915) Streptococcus pneumoniae Taiwan19F-14 7687260 YP_002743445.1 CDS SPT_2129 NC_012469.1 1981925 1982239 R hypothetical protein complement(1981925..1982239) Streptococcus pneumoniae Taiwan19F-14 7686717 YP_002743446.1 CDS SPT_2130 NC_012469.1 1982193 1982345 R identified by glimmer; putative; hypothetical protein complement(1982193..1982345) Streptococcus pneumoniae Taiwan19F-14 7685327 YP_002743447.1 CDS SPT_2131 NC_012469.1 1982389 1982535 R chlorohydrolase complement(1982389..1982535) Streptococcus pneumoniae Taiwan19F-14 7687056 YP_002743448.1 CDS hisS NC_012469.1 1982532 1983821 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1982532..1983821) Streptococcus pneumoniae Taiwan19F-14 7685785 YP_002743449.1 CDS SPT_2133 NC_012469.1 1983899 1985146 R identified by match to protein family HMM PF07690; transporter, major facilitator family complement(1983899..1985146) Streptococcus pneumoniae Taiwan19F-14 7686804 YP_002743450.1 CDS SPT_2134 NC_012469.1 1985337 1986098 R identified by match to protein family HMM TIGR01716; positive transcriptional regulator of glucosyltransferase and Spp phenotype complement(1985337..1986098) Streptococcus pneumoniae Taiwan19F-14 7686806 YP_002743451.1 CDS SPT_2135 NC_012469.1 1986163 1986297 R hypothetical protein complement(1986163..1986297) Streptococcus pneumoniae Taiwan19F-14 7686949 YP_002743452.1 CDS SPT_2136 NC_012469.1 1986312 1986653 D identified by match to protein family HMM PF01883; hypothetical protein 1986312..1986653 Streptococcus pneumoniae Taiwan19F-14 7686504 YP_002743453.1 CDS SPT_2137 NC_012469.1 1986717 1986881 D identified by glimmer; putative; hypothetical protein 1986717..1986881 Streptococcus pneumoniae Taiwan19F-14 7685843 YP_002743454.1 CDS ilvD NC_012469.1 1986907 1988610 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1986907..1988610) Streptococcus pneumoniae Taiwan19F-14 7687354 YP_002743455.1 CDS SPT_2139 NC_012469.1 1988843 1989775 R identified by match to protein family HMM PF02779; match to protein family HMM PF02780; transketolase, C- subunit complement(1988843..1989775) Streptococcus pneumoniae Taiwan19F-14 7685783 YP_002743456.1 CDS SPT_2140 NC_012469.1 1989772 1990629 R identified by match to protein family HMM PF00456; transketolase, thiamine disphosphate-binding subunit complement(1989772..1990629) Streptococcus pneumoniae Taiwan19F-14 7686130 YP_002743457.1 CDS ulaA NC_012469.1 1990633 1991979 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(1990633..1991979) Streptococcus pneumoniae Taiwan19F-14 7686241 YP_002743458.1 CDS SPT_2142 NC_012469.1 1991992 1992276 R identified by match to protein family HMM PF02302; phosphotransferase system, galactitol-specific IIB component complement(1991992..1992276) Streptococcus pneumoniae Taiwan19F-14 7685882 YP_002743459.1 CDS SPT_2143 NC_012469.1 1992280 1994310 R identified by match to protein family HMM PF00359; match to protein family HMM PF00874; transcriptional regulator, BglG family protein complement(1992280..1994310) Streptococcus pneumoniae Taiwan19F-14 7686531 YP_002743460.1 CDS SPT_2144 NC_012469.1 1994501 1995508 D identified by match to protein family HMM PF01145; integral membrane protein 1994501..1995508 Streptococcus pneumoniae Taiwan19F-14 7685689 YP_002743461.1 CDS SPT_2145 NC_012469.1 1995511 1995711 D hypothetical protein 1995511..1995711 Streptococcus pneumoniae Taiwan19F-14 7686822 YP_002743462.1 CDS rpmF NC_012469.1 1995863 1996045 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1995863..1996045 Streptococcus pneumoniae Taiwan19F-14 7687086 YP_002743463.1 CDS rpmG NC_012469.1 1996061 1996210 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1996061..1996210 Streptococcus pneumoniae Taiwan19F-14 7686918 YP_002743464.1 CDS SPT_2148 NC_012469.1 1996690 1998555 R identified by match to protein family HMM PF01473; choline binding protein PcpA complement(1996690..1998555) Streptococcus pneumoniae Taiwan19F-14 7686488 YP_002743465.1 CDS SPT_2151 NC_012469.1 1999029 1999250 D an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; transposase 1999029..1999250 Streptococcus pneumoniae Taiwan19F-14 7685975 YP_002743466.1 CDS SPT_2152 NC_012469.1 1999477 1999866 D identified by match to protein family HMM PF01609; transposase (IS4 family) 1999477..1999866 Streptococcus pneumoniae Taiwan19F-14 7685350 YP_002743467.1 CDS SPT_2153 NC_012469.1 1999918 2000193 R hypothetical protein complement(1999918..2000193) Streptococcus pneumoniae Taiwan19F-14 7685248 YP_002743468.1 CDS SPT_2154 NC_012469.1 2000571 2002451 R identified by match to protein family HMM PF00728; N-acetyl-beta-D-glucosaminidase complement(2000571..2002451) Streptococcus pneumoniae Taiwan19F-14 7686408 YP_002743469.1 CDS SPT_2155 NC_012469.1 2002445 2003314 R identified by match to protein family HMM PF00480; ROK family protein complement(2002445..2003314) Streptococcus pneumoniae Taiwan19F-14 7686603 YP_002743470.1 CDS SPT_2156 NC_012469.1 2003398 2006043 R identified by match to protein family HMM PF01074; match to protein family HMM PF07748; glycosyl hydrolase, family 38 complement(2003398..2006043) Streptococcus pneumoniae Taiwan19F-14 7686291 YP_002743471.1 CDS SPT_2157 NC_012469.1 2006134 2007414 R identified by match to protein family HMM PF06824; twin-arginine translocation pathway signal complement(2006134..2007414) Streptococcus pneumoniae Taiwan19F-14 7686497 YP_002743472.1 CDS SPT_2158 NC_012469.1 2007585 2009669 D identified by match to protein family HMM PF07971; match to protein family HMM TIGR01180; antigen, cell wall surface anchor family 2007585..2009669 Streptococcus pneumoniae Taiwan19F-14 7687205 YP_002743473.1 CDS SPT_2159 NC_012469.1 2009709 2011388 R identified by match to protein family HMM PF00754; putative alpha-L-fucosidase 1 (Alpha-L-fucoside fucohydrolase) complement(2009709..2011388) Streptococcus pneumoniae Taiwan19F-14 7685929 YP_002743474.1 CDS arcA NC_012469.1 2012144 2013373 D catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2012144..2013373 Streptococcus pneumoniae Taiwan19F-14 7685459 YP_002743475.1 CDS argF NC_012469.1 2013431 2014447 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2013431..2014447 Streptococcus pneumoniae Taiwan19F-14 7686897 YP_002743476.1 CDS arcC NC_012469.1 2014612 2015559 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2014612..2015559 Streptococcus pneumoniae Taiwan19F-14 7687384 YP_002743477.1 CDS SPT_2163 NC_012469.1 2015770 2017281 D identified by match to protein family HMM PF03606; arginine-ornithine antiporter 2015770..2017281 Streptococcus pneumoniae Taiwan19F-14 7686237 YP_002743478.1 CDS SPT_2164 NC_012469.1 2017303 2018634 D identified by match to protein family HMM PF01546; match to protein family HMM TIGR01887; hypothetical protein 2017303..2018634 Streptococcus pneumoniae Taiwan19F-14 7687141 YP_002743479.1 CDS SPT_2165 NC_012469.1 2018729 2018857 D an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase 2018729..2018857 Streptococcus pneumoniae Taiwan19F-14 7685724 YP_002743480.1 CDS SPT_2166 NC_012469.1 2019115 2019330 R identified by glimmer; putative; hypothetical protein complement(2019115..2019330) Streptococcus pneumoniae Taiwan19F-14 7685270 YP_002743481.1 CDS SPT_2167 NC_012469.1 2019318 2019584 R identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168; gram-positive signal peptide, ysirk family protein complement(2019318..2019584) Streptococcus pneumoniae Taiwan19F-14 7687176 YP_002743482.1 CDS SPT_2168 NC_012469.1 2019773 2019940 D identified by glimmer; putative; hypothetical protein 2019773..2019940 Streptococcus pneumoniae Taiwan19F-14 7685623 YP_002743483.1 CDS SPT_2169 NC_012469.1 2019967 2020866 R identified by match to protein family HMM PF01145; spfh domain/band 7 family complement(2019967..2020866) Streptococcus pneumoniae Taiwan19F-14 7685792 YP_002743484.1 CDS SPT_2170 NC_012469.1 2020996 2022147 R identified by match to protein family HMM PF00465; NAD-dependent methanol dehydrogenase (medh) complement(2020996..2022147) Streptococcus pneumoniae Taiwan19F-14 7685204 YP_002743485.1 CDS fucI NC_012469.1 2022293 2024059 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(2022293..2024059) Streptococcus pneumoniae Taiwan19F-14 7686718 YP_002743486.1 CDS SPT_2172 NC_012469.1 2024116 2027034 R identified by match to protein family HMM PF00754; match to protein family HMM PF08307; glycosyl hydrolase family 98 C- domain protein complement(2024116..2027034) Streptococcus pneumoniae Taiwan19F-14 7686103 YP_002743487.1 CDS SPT_2173 NC_012469.1 2027242 2029536 R large secreted protein complement(2027242..2029536) Streptococcus pneumoniae Taiwan19F-14 7686089 YP_002743488.1 CDS SPT_2174 NC_012469.1 2029595 2030395 R identified by match to protein family HMM PF03613; mannose permease iid component (pts system mannose-specific eiidcomponent) (eiid-man) (eii-m-man) complement(2029595..2030395) Streptococcus pneumoniae Taiwan19F-14 7686872 YP_002743489.1 CDS SPT_2175 NC_012469.1 2030392 2031165 R identified by match to protein family HMM PF03609; phosphotransferase system sugar-specific EII component complement(2030392..2031165) Streptococcus pneumoniae Taiwan19F-14 7685849 YP_002743490.1 CDS SPT_2176 NC_012469.1 2031190 2031660 R identified by match to protein family HMM PF03830; PTS system, IIB component complement(2031190..2031660) Streptococcus pneumoniae Taiwan19F-14 7687336 YP_002743491.1 CDS SPT_2177 NC_012469.1 2031651 2032094 R identified by match to protein family HMM PF03610; PTS system, IIA component complement(2031651..2032094) Streptococcus pneumoniae Taiwan19F-14 7685615 YP_002743492.1 CDS SPT_2178 NC_012469.1 2032075 2032515 R identified by match to protein family HMM PF05025; fucose operon FucU protein complement(2032075..2032515) Streptococcus pneumoniae Taiwan19F-14 7686332 YP_002743493.1 CDS SPT_2179 NC_012469.1 2032527 2033165 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(2032527..2033165) Streptococcus pneumoniae Taiwan19F-14 7686923 YP_002743494.1 CDS SPT_2180 NC_012469.1 2033280 2034683 R identified by match to protein family HMM PF00370; match to protein family HMM PF02782; rhamnulokinase (Rhamnulose kinase) complement(2033280..2034683) Streptococcus pneumoniae Taiwan19F-14 7686668 YP_002743495.1 CDS SPT_2181 NC_012469.1 2034859 2035632 D identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279; regulator of fucose operon 2034859..2035632 Streptococcus pneumoniae Taiwan19F-14 7685990 YP_002743496.1 CDS SPT_2182 NC_012469.1 2036803 2038308 R identified by match to protein family HMM PF01297; match to protein family HMM PF09223; zinc-binding lipoprotein AdcA complement(2036803..2038308) Streptococcus pneumoniae Taiwan19F-14 7687033 YP_002743497.1 CDS SPT_2183 NC_012469.1 2038318 2039124 R identified by match to protein family HMM PF00950; zinc ABC transporter permease complement(2038318..2039124) Streptococcus pneumoniae Taiwan19F-14 7686552 YP_002743498.1 CDS SPT_2184 NC_012469.1 2039117 2039821 R identified by match to protein family HMM PF00005; zinc transport system ATP-binding protein AdcC complement(2039117..2039821) Streptococcus pneumoniae Taiwan19F-14 7686310 YP_002743499.1 CDS SPT_2185 NC_012469.1 2039821 2040261 R identified by match to protein family HMM PF01022; match to protein family HMM PF01047; match to protein family HMM PF01325; match to protein family HMM PF01978; match to protein family HMM PF08279; putative transcriptional repressor complement(2039821..2040261) Streptococcus pneumoniae Taiwan19F-14 7685323 YP_002743500.1 CDS SPT_2186 NC_012469.1 2040246 2040383 D hypothetical protein 2040246..2040383 Streptococcus pneumoniae Taiwan19F-14 7686817 YP_002743501.1 CDS dltC NC_012469.1 2041677 2041916 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(2041677..2041916) Streptococcus pneumoniae Taiwan19F-14 7687349 YP_002743502.1 CDS SPT_2190 NC_012469.1 2041930 2043174 R identified by match to protein family HMM PF03062; protein DltB complement(2041930..2043174) Streptococcus pneumoniae Taiwan19F-14 7686464 YP_002743503.1 CDS dltA NC_012469.1 2043171 2044721 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(2043171..2044721) Streptococcus pneumoniae Taiwan19F-14 7685450 YP_002743504.1 CDS SPT_2192 NC_012469.1 2044742 2044873 R hypothetical protein complement(2044742..2044873) Streptococcus pneumoniae Taiwan19F-14 7685299 YP_002743505.1 CDS SPT_2193 NC_012469.1 2045187 2046365 R identified by match to protein family HMM PF07690; permease of the major facilitator superfamily complement(2045187..2046365) Streptococcus pneumoniae Taiwan19F-14 7685884 YP_002743506.1 CDS SPT_2196 NC_012469.1 2049214 2049801 D hypothetical protein 2049214..2049801 Streptococcus pneumoniae Taiwan19F-14 7687320 YP_002743507.1 CDS SPT_2197 NC_012469.1 2049888 2050091 R identified by glimmer; putative; hypothetical protein complement(2049888..2050091) Streptococcus pneumoniae Taiwan19F-14 7687329 YP_002743508.1 CDS SPT_2198 NC_012469.1 2050193 2050309 D identified by glimmer; putative; hypothetical protein 2050193..2050309 Streptococcus pneumoniae Taiwan19F-14 7685931 YP_002743509.1 CDS SPT_2199 NC_012469.1 2050388 2051092 R identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein complement(2050388..2051092) Streptococcus pneumoniae Taiwan19F-14 7685351 YP_002743510.1 CDS SPT_2200 NC_012469.1 2051162 2052988 R identified by match to protein family HMM PF01266; alpha-glycerophosphate oxidase (Glycerol-3-phosphateoxidase) (Exported protein 6) complement(2051162..2052988) Streptococcus pneumoniae Taiwan19F-14 7686126 YP_002743511.1 CDS glpK NC_012469.1 2053030 2054538 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(2053030..2054538) Streptococcus pneumoniae Taiwan19F-14 7685401 YP_002743512.1 CDS SPT_2202 NC_012469.1 2054697 2056106 R identified by match to protein family HMM PF05043; M protein trans-acting positive regulator (MGA) complement(2054697..2056106) Streptococcus pneumoniae Taiwan19F-14 7686636 YP_002743513.1 CDS hslO NC_012469.1 2056289 2057161 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2056289..2057161 Streptococcus pneumoniae Taiwan19F-14 7686360 YP_002743514.1 CDS SPT_2204 NC_012469.1 2057148 2058128 D identified by match to protein family HMM PF00724; match to protein family HMM PF01180; match to protein family HMM PF01207; match to protein family HMM TIGR00737; tRNA-dihydrouridine synthase B 2057148..2058128 Streptococcus pneumoniae Taiwan19F-14 7687025 YP_002743515.1 CDS SPT_2208 NC_012469.1 2061822 2063525 R identified by match to protein family HMM PF01473; surface protein PspC complement(2061822..2063525) Streptococcus pneumoniae Taiwan19F-14 7685476 YP_002743516.1 CDS SPT_2209 NC_012469.1 2063940 2064467 R identified by match to protein family HMM PF04140; hypothetical protein complement(2063940..2064467) Streptococcus pneumoniae Taiwan19F-14 7686997 YP_002743517.1 CDS SPT_2210 NC_012469.1 2064562 2065893 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; histidine kinase complement(2064562..2065893) Streptococcus pneumoniae Taiwan19F-14 7686354 YP_002743518.1 CDS SPT_2211 NC_012469.1 2065890 2066543 R identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator complement(2065890..2066543) Streptococcus pneumoniae Taiwan19F-14 7687208 YP_002743519.1 CDS SPT_2212 NC_012469.1 2066983 2067114 D DNA alkylation repair enzyme 2066983..2067114 Streptococcus pneumoniae Taiwan19F-14 7685647 YP_002743520.1 CDS SPT_2213 NC_012469.1 2067185 2069617 R identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; chaperone ClpB 1 complement(2067185..2069617) Streptococcus pneumoniae Taiwan19F-14 7685499 YP_002743521.1 CDS SPT_2214 NC_012469.1 2069619 2070077 R identified by match to protein family HMM PF05848; transcriptional regulator CtsR complement(2069619..2070077) Streptococcus pneumoniae Taiwan19F-14 7686767 YP_002743522.1 CDS SPT_2215 NC_012469.1 2070196 2070924 R identified by match to protein family HMM PF00005; anion ABC transporter ATP-binding protein complement(2070196..2070924) Streptococcus pneumoniae Taiwan19F-14 7686443 YP_002743523.1 CDS SPT_2216 NC_012469.1 2070924 2071931 R identified by match to protein family HMM PF09084; ABC transporter substrate-binding protein complement(2070924..2071931) Streptococcus pneumoniae Taiwan19F-14 7686411 YP_002743524.1 CDS SPT_2217 NC_012469.1 2071969 2072730 R identified by match to protein family HMM PF00528; ABC transporter permease complement(2071969..2072730) Streptococcus pneumoniae Taiwan19F-14 7686627 YP_002743525.1 CDS SPT_2218 NC_012469.1 2072690 2072980 R hypothetical protein complement(2072690..2072980) Streptococcus pneumoniae Taiwan19F-14 7687278 YP_002743526.1 CDS SPT_2219 NC_012469.1 2073236 2074582 R identified by match to protein family HMM PF01473; match to protein family HMM PF05257; match to protein family HMM PF08460; choline binding protein D complement(2073236..2074582) Streptococcus pneumoniae Taiwan19F-14 7686492 YP_002743527.1 CDS SPT_2220 NC_012469.1 2074671 2074937 R identified by match to protein family HMM PF06257; hypothetical protein complement(2074671..2074937) Streptococcus pneumoniae Taiwan19F-14 7686020 YP_002743528.1 CDS dnaB NC_012469.1 2074939 2076291 R unwinds double stranded DNA; replicative DNA helicase complement(2074939..2076291) Streptococcus pneumoniae Taiwan19F-14 7685962 YP_002743529.1 CDS rplI NC_012469.1 2076335 2076787 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(2076335..2076787) Streptococcus pneumoniae Taiwan19F-14 7686311 YP_002743530.1 CDS SPT_2223 NC_012469.1 2076784 2078757 R identified by match to protein family HMM PF01368; match to protein family HMM PF02272; DHH subfamily 1 protein complement(2076784..2078757) Streptococcus pneumoniae Taiwan19F-14 7687140 YP_002743531.1 CDS SPT_2224 NC_012469.1 2078893 2079441 R identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosome-associated protein Y complement(2078893..2079441) Streptococcus pneumoniae Taiwan19F-14 7685892 YP_002743532.1 CDS SPT_2225 NC_012469.1 2079521 2080183 R putative competence protein ComF complement(2079521..2080183) Streptococcus pneumoniae Taiwan19F-14 7685212 YP_002743533.1 CDS SPT_2226 NC_012469.1 2080180 2081478 R identified by match to protein family HMM PF00271; match to protein family HMM PF04851; superfamily II ATP-dependent DNA/RNA helicase required for DNA uptake complement(2080180..2081478) Streptococcus pneumoniae Taiwan19F-14 7685378 YP_002743534.1 CDS SPT_2227 NC_012469.1 2081534 2082169 D identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257; hypothetical protein 2081534..2082169 Streptococcus pneumoniae Taiwan19F-14 7685630 YP_002743535.1 CDS cysK NC_012469.1 2082454 2083374 D identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase A 2082454..2083374 Streptococcus pneumoniae Taiwan19F-14 7685718 YP_002743536.1 CDS SPT_2229 NC_012469.1 2083571 2083840 R an automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; transposase complement(2083571..2083840) Streptococcus pneumoniae Taiwan19F-14 7685620 YP_002743537.1 CDS SPT_2230 NC_012469.1 2084002 2084268 D transposase family protein 2084002..2084268 Streptococcus pneumoniae Taiwan19F-14 7685390 YP_002743538.1 CDS SPT_2231 NC_012469.1 2084409 2084732 R identified by match to protein family HMM PF05717; IS66 family element, Orf2 complement(2084409..2084732) Streptococcus pneumoniae Taiwan19F-14 7686067 YP_002743539.1 CDS tsf NC_012469.1 2084978 2086018 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(2084978..2086018) Streptococcus pneumoniae Taiwan19F-14 7685339 YP_002743540.1 CDS rpsB NC_012469.1 2086097 2086876 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(2086097..2086876) Streptococcus pneumoniae Taiwan19F-14 7687236 YP_002743541.1 CDS SPT_2234 NC_012469.1 2087100 2088278 R identified by match to protein family HMM PF05257; general stress protein GSP-781 complement(2087100..2088278) Streptococcus pneumoniae Taiwan19F-14 7686418 YP_002743542.1 CDS mreD NC_012469.1 2088372 2088866 R identified by match to protein family HMM PF04093; match to protein family HMM TIGR03426; rod shape-determining protein MreD complement(2088372..2088866) Streptococcus pneumoniae Taiwan19F-14 7686638 YP_002743543.1 CDS mreC NC_012469.1 2088866 2089684 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(2088866..2089684) Streptococcus pneumoniae Taiwan19F-14 7686330 YP_002743544.1 CDS SPT_2237 NC_012469.1 2089743 2090537 R identified by match to protein family HMM PF02361; ABC transporter permease complement(2089743..2090537) Streptococcus pneumoniae Taiwan19F-14 7685740 YP_002743545.1 CDS cbiO NC_012469.1 2090530 2091369 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2090530..2091369) Streptococcus pneumoniae Taiwan19F-14 7686200 YP_002743546.1 CDS cbiO NC_012469.1 2091354 2092181 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2091354..2092181) Streptococcus pneumoniae Taiwan19F-14 7685614 YP_002743547.1 CDS pgsA NC_012469.1 2092178 2092723 R identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2092178..2092723) Streptococcus pneumoniae Taiwan19F-14 7686727 YP_002743548.1 CDS SPT_2241 NC_012469.1 2092734 2093555 R hypothetical protein complement(2092734..2093555) Streptococcus pneumoniae Taiwan19F-14 7686366 YP_002743549.1 CDS SPT_2242 NC_012469.1 2093597 2094880 R identified by match to protein family HMM PF00675; match to protein family HMM PF05193; peptidase, M16 family complement(2093597..2094880) Streptococcus pneumoniae Taiwan19F-14 7685804 YP_002743550.1 CDS SPT_2243 NC_012469.1 2094877 2096127 R identified by match to protein family HMM PF05193; peptidase, M16 family complement(2094877..2096127) Streptococcus pneumoniae Taiwan19F-14 7685840 YP_002743551.1 CDS SPT_2244 NC_012469.1 2096286 2096654 D identified by match to protein family HMM TIGR02988; S4 domain protein YaaA, putative 2096286..2096654 Streptococcus pneumoniae Taiwan19F-14 7686754 YP_002743552.1 CDS recF NC_012469.1 2096657 2097754 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2096657..2097754 Streptococcus pneumoniae Taiwan19F-14 7685525 YP_002743553.1 CDS guaB NC_012469.1 2097805 2099283 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2097805..2099283) Streptococcus pneumoniae Taiwan19F-14 7686963 YP_002743554.1 CDS trpS NC_012469.1 2099435 2100460 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II complement(2099435..2100460) Streptococcus pneumoniae Taiwan19F-14 7686534 YP_002743555.1 CDS SPT_2248 NC_012469.1 2100666 2102288 D identified by match to protein family HMM PF00005; ATPase component of ABC transporters with duplicated ATPase domains 2100666..2102288 Streptococcus pneumoniae Taiwan19F-14 7686885 YP_002743556.1 CDS SPT_2249 NC_012469.1 2102350 2104902 D ABC transporter permease 2102350..2104902 Streptococcus pneumoniae Taiwan19F-14 7686523 YP_002743557.1 CDS SPT_2250 NC_012469.1 2105003 2105356 R identified by glimmer; putative; hypothetical protein complement(2105003..2105356) Streptococcus pneumoniae Taiwan19F-14 7685814 YP_002743558.1 CDS SPT_2251 NC_012469.1 2105353 2105850 R identified by glimmer; putative; hypothetical protein complement(2105353..2105850) Streptococcus pneumoniae Taiwan19F-14 7685976 YP_002743559.1 CDS SPT_2252 NC_012469.1 2106186 2106728 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2106186..2106728 Streptococcus pneumoniae Taiwan19F-14 7685967 YP_002743560.1 CDS SPT_2255 NC_012469.1 2106971 2107723 R identified by match to protein family HMM PF00072; match to protein family HMM PF04397; response regulator complement(2106971..2107723) Streptococcus pneumoniae Taiwan19F-14 7686579 YP_002743561.1 CDS SPT_2256 NC_012469.1 2107720 2109045 R identified by match to protein family HMM PF02518; histidine protein kinase complement(2107720..2109045) Streptococcus pneumoniae Taiwan19F-14 7685710 YP_002743562.1 CDS SPT_2257 NC_012469.1 2109066 2109191 R identified by match to protein family HMM PF03047; hypothetical protein complement(2109066..2109191) Streptococcus pneumoniae Taiwan19F-14 7686999 YP_002743563.1 CDS SPT_2259 NC_012469.1 2109473 2109952 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2109473..2109952) Streptococcus pneumoniae Taiwan19F-14 7685572 YP_002743564.1 CDS SPT_2260 NC_012469.1 2110135 2111316 D identified by match to protein family HMM PF00089; trypsin domain protein 2110135..2111316 Streptococcus pneumoniae Taiwan19F-14 7685639 YP_002743565.1 CDS SPT_2261 NC_012469.1 2111374 2112132 D identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; stage 0 sporulation protein J 2111374..2112132 Streptococcus pneumoniae Taiwan19F-14 7686551 SPT_0049 tRNA SPT_0049 NC_012469.1 35304 35378 D tRNA-Glu 35304..35378 Streptococcus pneumoniae Taiwan19F-14 7687331 SPT_0051 tRNA SPT_0051 NC_012469.1 37224 37301 D tRNA-Ala 37224..37301 Streptococcus pneumoniae Taiwan19F-14 7685553 SPT_0055 tRNA SPT_0055 NC_012469.1 40521 40597 D tRNA-Asn 40521..40597 Streptococcus pneumoniae Taiwan19F-14 7685552 SPT_0934 tRNA SPT_0934 NC_012469.1 880155 880229 D tRNA-Arg 880155..880229 Streptococcus pneumoniae Taiwan19F-14 7685861 SPT_0980 tRNA SPT_0980 NC_012469.1 922933 923009 D tRNA-Arg 922933..923009 Streptococcus pneumoniae Taiwan19F-14 7686471 SPT_1066 tRNA SPT_1066 NC_012469.1 1009455 1009530 D tRNA-Thr 1009455..1009530 Streptococcus pneumoniae Taiwan19F-14 7686052 SPT_1327 tRNA SPT_1327 NC_012469.1 1268040 1268132 D tRNA-Ser 1268040..1268132 Streptococcus pneumoniae Taiwan19F-14 7685320 SPT_1341 tRNA SPT_1341 NC_012469.1 1282627 1282701 R tRNA-Gln complement(1282627..1282701) Streptococcus pneumoniae Taiwan19F-14 7687003 SPT_1342 tRNA SPT_1342 NC_012469.1 1282708 1282791 R tRNA-Tyr complement(1282708..1282791) Streptococcus pneumoniae Taiwan19F-14 7685592 SPT_1521 tRNA SPT_1521 NC_012469.1 1450515 1450603 R tRNA-Leu complement(1450515..1450603) Streptococcus pneumoniae Taiwan19F-14 7685824 SPT_1718 tRNA SPT_1718 NC_012469.1 1633724 1633801 D tRNA-Lys 1633724..1633801 Streptococcus pneumoniae Taiwan19F-14 7685786 SPT_1824 tRNA SPT_1824 NC_012469.1 1733704 1733796 R tRNA-Ser complement(1733704..1733796) Streptococcus pneumoniae Taiwan19F-14 7686695 SPT_1825 tRNA SPT_1825 NC_012469.1 1733798 1733876 R tRNA-Ile complement(1733798..1733876) Streptococcus pneumoniae Taiwan19F-14 7685600 SPT_1826 tRNA SPT_1826 NC_012469.1 1733908 1733981 R tRNA-Gly complement(1733908..1733981) Streptococcus pneumoniae Taiwan19F-14 7685607 SPT_1827 tRNA SPT_1827 NC_012469.1 1733998 1734073 R tRNA-Phe complement(1733998..1734073) Streptococcus pneumoniae Taiwan19F-14 7685576 SPT_1828 tRNA SPT_1828 NC_012469.1 1734074 1734150 R tRNA-Met complement(1734074..1734150) Streptococcus pneumoniae Taiwan19F-14 7685597 SPT_1829 tRNA SPT_1829 NC_012469.1 1734158 1734250 R tRNA-Ser complement(1734158..1734250) Streptococcus pneumoniae Taiwan19F-14 7685567 SPT_1830 tRNA SPT_1830 NC_012469.1 1734258 1734334 R tRNA-Met complement(1734258..1734334) Streptococcus pneumoniae Taiwan19F-14 7685587 SPT_1831 tRNA SPT_1831 NC_012469.1 1734344 1734422 R tRNA-Met complement(1734344..1734422) Streptococcus pneumoniae Taiwan19F-14 7685598 SPT_1832 tRNA SPT_1832 NC_012469.1 1734423 1734501 R tRNA-Pro complement(1734423..1734501) Streptococcus pneumoniae Taiwan19F-14 7685575 SPT_1833 tRNA SPT_1833 NC_012469.1 1734513 1734589 R tRNA-Arg complement(1734513..1734589) Streptococcus pneumoniae Taiwan19F-14 7685584 SPT_1834 tRNA SPT_1834 NC_012469.1 1734596 1734684 R tRNA-Leu complement(1734596..1734684) Streptococcus pneumoniae Taiwan19F-14 7685564 SPT_1835 tRNA SPT_1835 NC_012469.1 1734689 1734763 R tRNA-Gly complement(1734689..1734763) Streptococcus pneumoniae Taiwan19F-14 7685566 SPT_1836 tRNA SPT_1836 NC_012469.1 1734783 1734858 R tRNA-Thr complement(1734783..1734858) Streptococcus pneumoniae Taiwan19F-14 7685611 SPT_1837 tRNA SPT_1837 NC_012469.1 1734873 1734959 R tRNA-Leu complement(1734873..1734959) Streptococcus pneumoniae Taiwan19F-14 7685596 SPT_1838 tRNA SPT_1838 NC_012469.1 1734961 1735036 R tRNA-Lys complement(1734961..1735036) Streptococcus pneumoniae Taiwan19F-14 7685589 SPT_1839 tRNA SPT_1839 NC_012469.1 1735061 1735133 R tRNA-Asp complement(1735061..1735133) Streptococcus pneumoniae Taiwan19F-14 7686576 SPT_2264 tRNA SPT_2264 NC_012469.1 1735136 1735208 R tRNA-Val complement(1735136..1735208) Streptococcus pneumoniae Taiwan19F-14 7685609 SPT_1843 tRNA SPT_1843 NC_012469.1 1738427 1738504 R tRNA-Ala complement(1738427..1738504) Streptococcus pneumoniae Taiwan19F-14 7685548 SPT_1845 tRNA SPT_1845 NC_012469.1 1740349 1740423 R tRNA-Glu complement(1740349..1740423) Streptococcus pneumoniae Taiwan19F-14 7685545 SPT_1940 tRNA SPT_1940 NC_012469.1 1821255 1821330 D tRNA-Cys 1821255..1821330 Streptococcus pneumoniae Taiwan19F-14 7687244 SPT_1988 tRNA SPT_1988 NC_012469.1 1860469 1860547 R tRNA-Pro complement(1860469..1860547) Streptococcus pneumoniae Taiwan19F-14 7687378 SPT_1989 tRNA SPT_1989 NC_012469.1 1860559 1860635 R tRNA-Arg complement(1860559..1860635) Streptococcus pneumoniae Taiwan19F-14 7685565 SPT_1990 tRNA SPT_1990 NC_012469.1 1860642 1860730 R tRNA-Leu complement(1860642..1860730) Streptococcus pneumoniae Taiwan19F-14 7685561 SPT_1991 tRNA SPT_1991 NC_012469.1 1860735 1860809 R tRNA-Gly complement(1860735..1860809) Streptococcus pneumoniae Taiwan19F-14 7685602 SPT_1992 tRNA SPT_1992 NC_012469.1 1860829 1860904 R tRNA-Thr complement(1860829..1860904) Streptococcus pneumoniae Taiwan19F-14 7685608 SPT_1993 tRNA SPT_1993 NC_012469.1 1860919 1861005 R tRNA-Leu complement(1860919..1861005) Streptococcus pneumoniae Taiwan19F-14 7685583 SPT_1994 tRNA SPT_1994 NC_012469.1 1861007 1861082 R tRNA-Lys complement(1861007..1861082) Streptococcus pneumoniae Taiwan19F-14 7685603 SPT_1995 tRNA SPT_1995 NC_012469.1 1861107 1861179 R tRNA-Asp complement(1861107..1861179) Streptococcus pneumoniae Taiwan19F-14 7685580 SPT_2266 tRNA SPT_2266 NC_012469.1 1861182 1861254 R tRNA-Val complement(1861182..1861254) Streptococcus pneumoniae Taiwan19F-14 7686575 SPT_1999 tRNA SPT_1999 NC_012469.1 1864473 1864550 R tRNA-Ala complement(1864473..1864550) Streptococcus pneumoniae Taiwan19F-14 7685547 SPT_2001 tRNA SPT_2001 NC_012469.1 1866396 1866470 R tRNA-Glu complement(1866396..1866470) Streptococcus pneumoniae Taiwan19F-14 7685550 SPT_2063 tRNA SPT_2063 NC_012469.1 1922288 1922376 R tRNA-Leu complement(1922288..1922376) Streptococcus pneumoniae Taiwan19F-14 7685720 SPT_2064 tRNA SPT_2064 NC_012469.1 1922381 1922457 R tRNA-Gln complement(1922381..1922457) Streptococcus pneumoniae Taiwan19F-14 7685582 SPT_2065 tRNA SPT_2065 NC_012469.1 1922463 1922540 R tRNA-His complement(1922463..1922540) Streptococcus pneumoniae Taiwan19F-14 7685574 SPT_2066 tRNA SPT_2066 NC_012469.1 1922554 1922626 R tRNA-Trp complement(1922554..1922626) Streptococcus pneumoniae Taiwan19F-14 7685606 SPT_2265 tRNA SPT_2265 NC_012469.1 1922629 1922709 R tRNA-Tyr complement(1922629..1922709) Streptococcus pneumoniae Taiwan19F-14 7685610 SPT_2067 tRNA SPT_2067 NC_012469.1 1922719 1922794 R tRNA-Phe complement(1922719..1922794) Streptococcus pneumoniae Taiwan19F-14 7685593 SPT_2068 tRNA SPT_2068 NC_012469.1 1922795 1922871 R tRNA-Met complement(1922795..1922871) Streptococcus pneumoniae Taiwan19F-14 7685569 SPT_2069 tRNA SPT_2069 NC_012469.1 1922879 1922971 R tRNA-Ser complement(1922879..1922971) Streptococcus pneumoniae Taiwan19F-14 7686574 SPT_2070 tRNA SPT_2070 NC_012469.1 1923050 1923128 R tRNA-Ile complement(1923050..1923128) Streptococcus pneumoniae Taiwan19F-14 7685578 SPT_2071 tRNA SPT_2071 NC_012469.1 1923158 1923233 R tRNA-Gly complement(1923158..1923233) Streptococcus pneumoniae Taiwan19F-14 7685573 SPT_2072 tRNA SPT_2072 NC_012469.1 1923235 1923310 R tRNA-Val complement(1923235..1923310) Streptococcus pneumoniae Taiwan19F-14 7686577 SPT_2076 tRNA SPT_2076 NC_012469.1 1926529 1926606 R tRNA-Ala complement(1926529..1926606) Streptococcus pneumoniae Taiwan19F-14 7685554 SPT_2078 tRNA SPT_2078 NC_012469.1 1928452 1928526 R tRNA-Glu complement(1928452..1928526) Streptococcus pneumoniae Taiwan19F-14 7685544 SPT_2253 tRNA SPT_2253 NC_012469.1 2106766 2106842 R tRNA-Asn complement(2106766..2106842) Streptococcus pneumoniae Taiwan19F-14 7685347 SPT_2254 tRNA SPT_2254 NC_012469.1 2106845 2106919 R tRNA-Glu complement(2106845..2106919) Streptococcus pneumoniae Taiwan19F-14 7685571 SPT_2258 tRNA SPT_2258 NC_012469.1 2109353 2109429 R tRNA-Arg complement(2109353..2109429) Streptococcus pneumoniae Taiwan19F-14 7686750 SPT_0050 rRNA rrs1 NC_012469.1 35641 37098 D 16S ribosomal RNA 35641..37098 Streptococcus pneumoniae Taiwan19F-14 7685585 SPT_0053 rRNA rrl1 NC_012469.1 37422 40323 D 23S ribosomal RNA 37422..40323 Streptococcus pneumoniae Taiwan19F-14 7685591 SPT_0054 rRNA rrf_1 NC_012469.1 40400 40515 D 5S ribosomal RNA 40400..40515 Streptococcus pneumoniae Taiwan19F-14 7685551 SPT_1840 rRNA rrf_2 NC_012469.1 1735213 1735328 R 5S ribosomal RNA complement(1735213..1735328) Streptococcus pneumoniae Taiwan19F-14 7686578 SPT_1841 rRNA rrl2 NC_012469.1 1735405 1738306 R 23S ribosomal RNA complement(1735405..1738306) Streptococcus pneumoniae Taiwan19F-14 7685546 SPT_1844 rRNA rrs2 NC_012469.1 1738630 1740087 R 16S ribosomal RNA complement(1738630..1740087) Streptococcus pneumoniae Taiwan19F-14 7685563 SPT_1996 rRNA rrf NC_012469.1 1861259 1861374 R 5S ribosomal RNA complement(1861259..1861374) Streptococcus pneumoniae Taiwan19F-14 7685577 SPT_1997 rRNA rrl3 NC_012469.1 1861451 1864352 R 23S ribosomal RNA complement(1861451..1864352) Streptococcus pneumoniae Taiwan19F-14 7685555 SPT_2000 rRNA rrs3 NC_012469.1 1864676 1866133 R 16S ribosomal RNA complement(1864676..1866133) Streptococcus pneumoniae Taiwan19F-14 7685594 SPT_2073 rRNA rrf_3 NC_012469.1 1923315 1923430 R 5S ribosomal RNA complement(1923315..1923430) Streptococcus pneumoniae Taiwan19F-14 7685590 SPT_2074 rRNA rrl4 NC_012469.1 1923507 1926408 R 23S ribosomal RNA complement(1923507..1926408) Streptococcus pneumoniae Taiwan19F-14 7685549 SPT_2077 rRNA rrs4 NC_012469.1 1926732 1928189 R 16S ribosomal RNA complement(1926732..1928189) Streptococcus pneumoniae Taiwan19F-14 7685562